@prefix rdf: . @prefix : . @prefix cl: . @prefix dc: . @prefix go: . @prefix pr: . @prefix obo: . @prefix owl: . @prefix xml: . @prefix xsd: . @prefix caro: . @prefix cito: . @prefix core: . @prefix fbbt: . @prefix foaf: . @prefix obo3: . @prefix pato: . @prefix rdfs: . @prefix skos: . @prefix swrl: . @prefix chebi: . @prefix swrla: . @prefix swrlb: . @prefix terms: . @prefix chebi2: . @prefix chebi4: . @prefix chebi5: . @prefix chebi6: . @prefix terms1: . @prefix ubprop: . @prefix protege: . @prefix subsets: . @prefix oboInOwl: . @prefix ncbitaxon: . @prefix wbphenotype: . @prefix caloha-reqs-vetted: . protege:defaultLanguage a owl:AnnotationProperty . obo:BFO_0000001 obo:BFO_0000179 "entity" ; obo:BFO_0000180 "Entity" ; obo:IAO_0000112 "Julius Caesar"@en, "Verdi’s Requiem"@en, "the Second World War"@en, "your body mass index"@en ; obo:IAO_0000116 "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81"@en, "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"@en ; obo:IAO_0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])"@en ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "entity"@en . obo:BFO_0000002 obo:BFO_0000179 "continuant" ; obo:BFO_0000180 "Continuant" ; obo:IAO_0000115 "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ; obo:IAO_0000116 "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240"@en, "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants"@en ; obo:IAO_0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])"@en ; obo:IAO_0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])"@en, "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])"@en, "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])"@en ; obo:IAO_0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] ", "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] ", "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] ", "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "continuant"@en ; rdfs:subClassOf obo:BFO_0000001, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000002 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith obo:BFO_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:BFO_0000003 ] . obo:BFO_0000003 obo:BFO_0000179 "occurrent" ; obo:BFO_0000180 "Occurrent" ; obo:IAO_0000115 "An entity that has temporal parts and that happens, unfolds or develops through time."@en ; obo:IAO_0000116 "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region"@en, "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players."@en, "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process."@en, "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." ; obo:IAO_0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])"@en ; obo:IAO_0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])"@en, "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] ", "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "occurrent"@en ; rdfs:subClassOf obo:BFO_0000001, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000003 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:BFO_0000002 ] . obo:BFO_0000004 obo:BFO_0000179 "ic" ; obo:BFO_0000180 "IndependentContinuant" ; obo:IAO_0000112 "a chair"@en, "a heart"@en, "a leg"@en, "a molecule"@en, "a spatial region"@en, "an atom"@en, "an orchestra."@en, "an organism"@en, "the bottom right portion of a human torso"@en, "the interior of your mouth"@en ; obo:IAO_0000115 "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything."@en, "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ; obo:IAO_0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])"@en, "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])"@en ; obo:IAO_0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] ", "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] ", "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "independent continuant"@en ; rdfs:subClassOf obo:BFO_0000002, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000004 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith obo:BFO_0000020, obo:BFO_0000031 . obo:BFO_0000006 a owl:Class ; rdfs:label "spatial region"@en ; rdfs:subClassOf obo:BFO_0000141 . obo:BFO_0000009 a owl:Class . obo:BFO_0000015 obo:IAO_0000115 "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t."@en ; a owl:Class ; rdfs:label "process"@en ; rdfs:subClassOf obo:BFO_0000003 . obo:BFO_0000016 obo:BFO_0000179 "disposition" ; obo:BFO_0000180 "Disposition" ; obo:IAO_0000112 "an atom of element X has the disposition to decay to an atom of element Y"@en, "certain people have a predisposition to colon cancer"@en, "children are innately disposed to categorize objects in certain ways."@en, "the cell wall is disposed to filter chemicals in endocytosis and exocytosis"@en ; obo:IAO_0000116 "BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type."@en ; obo:IAO_0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])"@en ; obo:IAO_0000601 "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])"@en ; obo:IAO_0000602 "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] ", "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "disposition"@en ; rdfs:subClassOf obo:BFO_0000017 ; owl:disjointWith obo:BFO_0000023 . obo:BFO_0000017 obo:BFO_0000179 "realizable" ; obo:BFO_0000180 "RealizableEntity" ; obo:IAO_0000112 "the disposition of this piece of metal to conduct electricity."@en, "the disposition of your blood to coagulate"@en, "the function of your reproductive organs"@en, "the role of being a doctor"@en, "the role of this boundary to delineate where Utah and Colorado meet"@en ; obo:IAO_0000115 "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ; obo:IAO_0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])"@en ; obo:IAO_0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])"@en ; obo:IAO_0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] ", "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "realizable entity"@en ; rdfs:subClassOf obo:BFO_0000020, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000017 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith obo:BFO_0000019 . obo:BFO_0000019 obo:BFO_0000179 "quality" ; obo:BFO_0000180 "Quality" ; obo:IAO_0000112 "the ambient temperature of this portion of air"@en, "the color of a tomato"@en, "the length of the circumference of your waist"@en, "the mass of this piece of gold."@en, "the shape of your nose"@en, "the shape of your nostril"@en ; obo:IAO_0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])"@en ; obo:IAO_0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] ", "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "quality"@en ; rdfs:subClassOf obo:BFO_0000020, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000019 ; owl:onProperty obo:BFO_0000050 ] . obo:BFO_0000020 obo:BFO_0000179 "sdc" ; obo:BFO_0000180 "SpecificallyDependentContinuant" ; obo:IAO_0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key"@en, "of one-sided specifically dependent continuants: the mass of this tomato"@en, "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates."@en, "the disposition of this fish to decay"@en, "the function of this heart: to pump blood"@en, "the mutual dependence of proton donors and acceptors in chemical reactions [79"@en, "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction"@en, "the pink color of a medium rare piece of grilled filet mignon at its center"@en, "the role of being a doctor"@en, "the shape of this hole."@en, "the smell of this portion of mozzarella"@en ; obo:IAO_0000115 "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en, "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en ; obo:IAO_0000116 "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc."@en ; obo:IAO_0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "specifically dependent continuant"@en ; rdfs:subClassOf obo:BFO_0000002, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000020 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith obo:BFO_0000031 . obo:BFO_0000023 obo:BFO_0000179 "role" ; obo:BFO_0000180 "Role" ; obo:IAO_0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married."@en, "the priest role"@en, "the role of a boundary to demarcate two neighboring administrative territories"@en, "the role of a building in serving as a military target"@en, "the role of a stone in marking a property boundary"@en, "the role of subject in a clinical trial"@en, "the student role"@en ; obo:IAO_0000115 "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts."@en ; obo:IAO_0000116 "BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives."@en ; obo:IAO_0000600 "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "role"@en ; rdfs:subClassOf obo:CHEBI_50906 ; owl:equivalentClass obo:CHEBI_50906 . obo:BFO_0000031 obo:BFO_0000179 "gdc" ; obo:BFO_0000180 "GenericallyDependentContinuant" ; obo:IAO_0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity."@en, "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop"@en, "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule."@en ; obo:IAO_0000115 "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en ; obo:IAO_0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "generically dependent continuant"@en ; rdfs:subClassOf obo:BFO_0000002 . obo:BFO_0000034 obo:BFO_0000179 "function" ; obo:BFO_0000180 "Function" ; obo:IAO_0000112 "the function of a hammer to drive in nails"@en, "the function of a heart pacemaker to regulate the beating of a heart through electricity"@en, "the function of amylase in saliva to break down starch into sugar"@en ; obo:IAO_0000116 "BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc."@en ; obo:IAO_0000600 "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "function"@en ; rdfs:subClassOf obo:BFO_0000016 . obo:BFO_0000040 obo:IAO_0000115 "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ; a owl:Class ; rdfs:label "material entity"@en ; rdfs:subClassOf obo:BFO_0000004 ; owl:disjointWith obo:BFO_0000141, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:BFO_0000141 ] . obo:BFO_0000050 obo:IAO_0000111 "is part of"@en ; obo:IAO_0000112 "my brain is part of my body (continuant parthood, two material entities)"@en, "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"@en, "this day is part of this year (occurrent parthood)"@en ; obo:IAO_0000115 "a core relation that holds between a part and its whole"@en ; obo:IAO_0000116 "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."@en, "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en, """Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."""@en ; obo:IAO_0000118 "part_of"@en ; obo:RO_0001900 obo:RO_0001901 ; obo:RO_0040042 obo:BFO_0000002, obo:BFO_0000003, obo:BFO_0000004, obo:BFO_0000017, obo:BFO_0000019, obo:BFO_0000020, obo:BFO_0000031 ; oboInOwl:hasDbXref "BFO:0000050" ; oboInOwl:hasOBONamespace "external", "quality", "uberon", "worm_anatomy", "worm_development" ; oboInOwl:id "part_of" ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_gp2term, obo:valid_for_go_ontology, obo:valid_for_gocam ; oboInOwl:shorthand "part_of" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "part of", "part of"@en, "part_of" ; rdfs:seeAlso , , "http://www.obofoundry.org/ro/#OBO_REL:part_of" ; rdfs:subPropertyOf obo:RO_0002131 ; owl:inverseOf obo:BFO_0000051 . obo:BFO_0000051 obo:IAO_0000111 "has part"@en ; obo:IAO_0000112 "my body has part my brain (continuant parthood, two material entities)"@en, "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"@en, "this year has part this day (occurrent parthood)"@en ; obo:IAO_0000115 "a core relation that holds between a whole and its part"@en ; obo:IAO_0000116 "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."@en, "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en, """Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."""@en ; obo:IAO_0000118 "has_part"@en ; obo:RO_0001900 obo:RO_0001901 ; oboInOwl:hasDbXref "BFO:0000051" ; oboInOwl:hasOBONamespace "chebi_ontology", "external", "quality", "uberon" ; oboInOwl:id "has_part" ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; oboInOwl:is_cyclic false ; oboInOwl:shorthand "has_part" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "has part", "has part"@en, "has_part" ; rdfs:subPropertyOf obo:RO_0002131 . obo:BFO_0000062 obo:IAO_0000111 "preceded by"@en ; obo:IAO_0000115 "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ; obo:IAO_0000116 "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."@en ; obo:IAO_0000118 "is preceded by"@en, "preceded_by"@en ; dc:source "http://www.obofoundry.org/ro/#OBO_REL:preceded_by" ; oboInOwl:hasDbXref "BFO:0000062" ; oboInOwl:hasOBONamespace "external", "uberon", "worm_development" ; oboInOwl:id "preceded_by" ; oboInOwl:inSubset subsets:ro-eco ; oboInOwl:shorthand "preceded_by" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "preceded by", "preceded by"@en, "preceded_by" ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:RO_0002086 ; owl:inverseOf obo:BFO_0000063 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000062 ) . obo:BFO_0000063 obo:IAO_0000111 "precedes"@en ; obo:IAO_0000115 "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ; oboInOwl:hasDbXref "BFO:0000063" ; oboInOwl:hasOBONamespace "external", "uberon" ; oboInOwl:id "precedes" ; oboInOwl:inSubset subsets:ro-eco ; oboInOwl:shorthand "precedes" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "precedes", "precedes"@en ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:RO_0002222 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000063 ) . obo:BFO_0000066 obo:IAO_0000111 "occurs in"@en ; obo:IAO_0000115 "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ; obo:IAO_0000118 "occurs_in"@en, "unfolds in"@en, "unfolds_in"@en ; oboInOwl:hasDbXref "BFO:0000066" ; oboInOwl:hasOBONamespace "external", "gene_ontology" ; oboInOwl:id "occurs_in" ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; oboInOwl:shorthand "occurs_in" ; a owl:ObjectProperty ; rdfs:comment "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant" ; rdfs:domain obo:BFO_0000003 ; rdfs:isDefinedBy ; rdfs:label "occurs in", "occurs in"@en ; rdfs:range obo:BFO_0000004 ; owl:inverseOf obo:BFO_0000067 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000066 ), (obo:BFO_0000066 obo:BFO_0000050 ) . obo:BFO_0000067 obo:IAO_0000111 "site of"@en ; obo:IAO_0000115 "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ; oboInOwl:hasDbXref "BFO:0000067" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "contains_process" ; oboInOwl:shorthand "contains_process" ; a owl:ObjectProperty ; rdfs:comment "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant" ; rdfs:isDefinedBy ; rdfs:label "contains process", "contains process"@en . obo:BFO_0000070 a owl:ObjectProperty . obo:BFO_0000141 a owl:Class ; rdfs:label "immaterial entity"@en ; rdfs:subClassOf obo:BFO_0000004 ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:BFO_0000040 ] . obo:BFO_0000179 a owl:AnnotationProperty . obo:BFO_0000180 a owl:AnnotationProperty . obo:BSPO_0000096 oboInOwl:hasDbXref "BSPO:0000096" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "anterior_to" ; oboInOwl:shorthand "anterior_to" ; a owl:ObjectProperty ; rdfs:label "anterior to" . obo:BSPO_0000097 oboInOwl:hasDbXref "BSPO:0000097" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "distal_to" ; oboInOwl:shorthand "distal_to" ; a owl:ObjectProperty ; rdfs:label "distal to" . obo:BSPO_0000098 oboInOwl:hasDbXref "BSPO:0000098" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "dorsal_to" ; oboInOwl:shorthand "dorsal_to" ; a owl:ObjectProperty ; rdfs:label "dorsal to" . obo:BSPO_0000099 oboInOwl:hasDbXref "BSPO:0000099" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "posterior_to" ; oboInOwl:shorthand "posterior_to" ; a owl:ObjectProperty ; rdfs:label "posterior to" . obo:BSPO_0000100 oboInOwl:hasDbXref "BSPO:0000100" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "proximal_to" ; oboInOwl:shorthand "proximal_to" ; a owl:ObjectProperty ; rdfs:label "proximal to" . obo:BSPO_0000102 oboInOwl:hasDbXref "BSPO:0000102" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "ventral_to" ; oboInOwl:shorthand "ventral_to" ; a owl:ObjectProperty ; rdfs:label "ventral to" . obo:BSPO_0000107 oboInOwl:hasDbXref "BSPO:0000107" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "deep_to" ; oboInOwl:shorthand "deep_to" ; a owl:ObjectProperty ; rdfs:label "deep to" . obo:BSPO_0000108 oboInOwl:hasDbXref "BSPO:0000108" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "superficial_to" ; oboInOwl:shorthand "superficial_to" ; a owl:ObjectProperty ; rdfs:label "superficial to" . obo:BSPO_0000120 oboInOwl:hasDbXref "BSPO:0000120" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "in_left_side_of" ; oboInOwl:shorthand "in_left_side_of" ; a owl:ObjectProperty ; rdfs:label "in left side of" . obo:BSPO_0000121 oboInOwl:hasDbXref "BSPO:0000121" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "in_right_side_of" ; oboInOwl:shorthand "in_right_side_of" ; a owl:ObjectProperty ; rdfs:label "in right side of" . obo:BSPO_0000122 oboInOwl:hasDbXref "BSPO:0000122" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "in_posterior_side_of" ; oboInOwl:shorthand "in_posterior_side_of" ; a owl:ObjectProperty ; rdfs:label "in posterior side of" . obo:BSPO_0000123 oboInOwl:hasDbXref "BSPO:0000123" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "in_anterior_side_of" ; oboInOwl:shorthand "in_anterior_side_of" ; a owl:ObjectProperty ; rdfs:label "in anterior side of" . obo:BSPO_0000126 oboInOwl:hasDbXref "BSPO:0000126" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "in_lateral_side_of" ; oboInOwl:shorthand "in_lateral_side_of" ; a owl:ObjectProperty ; rdfs:label "in lateral side of" . obo:BSPO_0001106 oboInOwl:hasDbXref "BSPO:0001106" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "proximalmost_part_of" ; oboInOwl:shorthand "proximalmost_part_of" ; a owl:ObjectProperty ; rdfs:label "proximalmost part of" . obo:BSPO_0001107 oboInOwl:hasDbXref "BSPO:0001107" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "immediately_deep_to" ; oboInOwl:shorthand "immediately_deep_to" ; a owl:ObjectProperty ; rdfs:label "immediately deep to" . obo:BSPO_0001108 oboInOwl:hasDbXref "BSPO:0001108" ; oboInOwl:hasOBONamespace "uberon" ; oboInOwl:id "distalmost_part_of" ; oboInOwl:shorthand "distalmost_part_of" ; a owl:ObjectProperty ; rdfs:label "distalmost part of" . obo:CARO_0000000 obo:IAO_0000115 "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." ; oboInOwl:id "CARO:0000000" ; a owl:Class ; rdfs:comment "Following BFO, material anatomical entities may have immaterial parts (the lumen of your stomach is part of your stomach). The granularity limit follows the limits set by the Gene Ontology on the granularity limit for GO:cellular_component. Note that substances produced by an organism (sweat, feaces, urine) do not need to be part of an organism to qualify as an anatomical structure." ; rdfs:label "anatomical entity" ; rdfs:subClassOf obo:CARO_0030000 ; owl:disjointUnionOf (obo:CARO_0000006 obo:CARO_0000007 ) . obo:CARO_0000003 obo:IAO_0000115 "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ; oboInOwl:id "CARO:0000003" ; oboInOwl:inSubset caro:core ; a owl:Class ; rdfs:comment "Note that the definition does not say 'generated exclusively by the co-ordinated expression of the organism's own genome', so this is still valid for cases where normal morphogenesis requires the actions of a facultative symbiont, or some looser dependency such as the a requirement for the presence of gut flora for normal gut development." ; rdfs:label "connected anatomical structure" ; rdfs:subClassOf obo:CARO_0000006, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002266 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0010000 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CARO_0000006 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002266 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0010000 ] ) ] . obo:CARO_0000004 obo:IAO_0000112 "Examples include feces, urine, blood, blood plasma, lymph, hemolymph, cerbro-spinal fluid. This class does not encompass anatomical entities with inherent 3D structure such as dentine and arthropod cuticle." ; obo:IAO_0000115 "Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body and that does not have inherent 3D shape generated by coordinated expression of the organism's own genome." ; oboInOwl:hasExactSynonym "portion of organism substance" ; oboInOwl:id "CARO:0000004" ; a owl:Class ; rdfs:comment "Note - CARO explicitly declares organisms substances to be part of (some) organism." ; rdfs:label "organism substance" ; rdfs:subClassOf obo:CARO_0001008 . obo:CARO_0000006 obo:IAO_0000115 "An anatomical entity that has mass." ; oboInOwl:id "CARO:0000006" ; oboInOwl:inSubset caro:core ; a owl:Class ; rdfs:label "material anatomical entity" ; rdfs:subClassOf obo:CARO_0000000, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000125 ] ; owl:disjointWith obo:CARO_0000007, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CARO_0000007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CARO_0000000 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000125 ] ) ] . obo:CARO_0000007 obo:IAO_0000115 "Anatomical entity that has no mass." ; oboInOwl:id "CARO:0000007" ; oboInOwl:inSubset caro:core ; a owl:Class ; rdfs:label "immaterial anatomical entity" ; rdfs:subClassOf obo:BFO_0000141, obo:CARO_0000000 ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CARO_0000006 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CARO_0000000 [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000125 ] ] ) ] . obo:CARO_0000010 obo:IAO_0000115 "A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures." ; a owl:Class ; rdfs:comment "Except in the case of abstracted fiat boundaries such as the midline plane of an organism, all 2D anatomical entities have a 3 dimensional projection. For example, the surface of the shell of a muscle has a distinct shape that projects into the third dimension. Note that boundaries are 2D structures. They have no thickness - and so can not be sites of gene expression or gene product localisation. For this, use boundary region terms." ; rdfs:label "anatomical boundary" ; rdfs:subClassOf obo:BFO_0000009, obo:CARO_0000007 . obo:CARO_0000012 obo:IAO_0000115 "Anatomical structure that is an individual member of a clade and, at some point in its life-cycle, consists of more than one cell." ; oboInOwl:id "CARO:0000012" ; a owl:Class ; rdfs:comment """MH: Can't define this class based on 2 or more cells because most multi cellular organisms (if not all) have only a single cell at some point in life history. MH: sexual subtypes should probably be logically defined based on sexual processes or sex qualities.""" ; rdfs:label "multicellular organism" ; rdfs:subClassOf obo:CARO_0010004 . obo:CARO_0000013 obo:IAO_0000115 "An anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ; oboInOwl:hasDbXref "CL:0000000", "GO:0005623" ; oboInOwl:id "CARO:0000013" ; a owl:Class ; rdfs:comment "deprecate and replace with CL or GO term?" ; rdfs:label "cell" ; rdfs:subClassOf obo:CARO_0000003, obo:CARO_0020003 ; owl:disjointWith obo:CARO_0000014, obo:CARO_0000040, obo:CARO_0000042, obo:CARO_0001000, obo:CARO_0010000 . obo:CARO_0000014 obo:IAO_0000115 "Anatomical structure that is part of a cell and that has a granularity level equal to that of a protein complex or higher." ; obo:IAO_0000118 "cell component" ; oboInOwl:id "CARO:0000014" ; a owl:Class ; rdfs:comment "This is declared equivalent with GO:0044464. The definition should be co-ordinated with GO. We could obsolete the CARO class and just use the GO class." ; rdfs:label "cell part"@en ; rdfs:subClassOf obo:CARO_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CARO_0000013 ] ; owl:disjointWith obo:CARO_0000040, obo:CARO_0000042, obo:CARO_0001000, obo:CARO_0010000 . obo:CARO_0000032 obo:IAO_0000115 "Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument."@en ; obo:IAO_0000116 "Old definition: Anatomical structure which is a primary subdivision of whole organism. The mereological sum of these is the whole organism." ; oboInOwl:id "CARO:0000032" ; oboInOwl:inSubset caro:core ; a owl:Class ; rdfs:label "organism subdivision" ; rdfs:subClassOf obo:CARO_0010000 . obo:CARO_0000040 obo:IAO_0000115 "An anatomical structure that has no cells or cell parts as a part." ; oboInOwl:id "CARO:0000040" ; a owl:Class ; rdfs:comment "Example. Insect cuticle, eggshell, hair." ; rdfs:label "acellular anatomical structure" ; rdfs:subClassOf obo:CARO_0000003, obo:CARO_0001008 ; owl:disjointWith obo:CARO_0000042, obo:CARO_0001000, obo:CARO_0010000 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CARO_0000003 [ a owl:Restriction ; owl:onClass obo:CARO_0000013 ; owl:onProperty obo:RO_0002180 ; owl:qualifiedCardinality "0"^^xsd:nonNegativeInteger ] [ a owl:Restriction ; owl:onClass obo:CARO_0000014 ; owl:onProperty obo:RO_0002180 ; owl:qualifiedCardinality "0"^^xsd:nonNegativeInteger ] ) ] . obo:CARO_0000042 obo:IAO_0000115 "A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis." ; oboInOwl:id "CARO:0000042" ; oboInOwl:inSubset caro:plus ; a owl:Class ; rdfs:comment """MH: define as not part of embryo, or will not develop into embryo? MH: changed def to exclude cells so this class could be included in gross anatomical part. DOS: Changed to something that I think works for both vertebrates and invertebrates and that keeps the restriction to multicellular structures. Old def: \"Anatomical structure that is contiguous with the embryo and is comprised of portions of tissue that will not contribute to the embryo.\". One remaining question - perhaps zygote is too restrictive given that some organisms have parthenogenesis e.g. aphids? """ ; rdfs:label "extraembryonic structure" ; rdfs:subClassOf obo:CARO_0000003, obo:CARO_0001008 ; owl:disjointWith obo:CARO_0001000, obo:CARO_0010000 . obo:CARO_0001000 obo:IAO_0000115 "A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part." ; obo:IAO_0000118 "multi-cell-component structure" ; oboInOwl:id "CARO:0001000" ; oboInOwl:inSubset caro:core ; a owl:Class ; rdfs:comment "Examples: a bundle of neuron projections in the brain; a region neuropil in an arthropod central nervous system; a region of cortex (preikaryal rind) in an arthropod brain." ; rdfs:label "multi-cell-part structure" ; rdfs:subClassOf obo:CARO_0001008, [ a owl:Class ; owl:intersectionOf (obo:CARO_0000003 [ a owl:Restriction ; owl:allValuesFrom [ a owl:Class ; owl:complementOf obo:CARO_0000013 ] ; owl:onProperty obo:BFO_0000051 ] [ a owl:Restriction ; owl:minQualifiedCardinality "2"^^xsd:nonNegativeInteger ; owl:onClass obo:CARO_0000014 ; owl:onProperty obo:RO_0002180 ] ) ] ; owl:disjointWith obo:CARO_0010000 . obo:CARO_0001001 obo:IAO_0000115 "A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses." ; obo:IAO_0000118 "nerve fiber bundle" ; oboInOwl:id "CARO:0001001" ; a owl:Class ; rdfs:label "neuron projection bundle" ; rdfs:subClassOf obo:CARO_0001000, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002309 ] . obo:CARO_0001008 obo:IAO_0000115 "Anatomical structure that is part of a multicellular organism and is at the gross anatomical level, e.g. above the level of a cell. Included are portions of organism substances such as blood, multi-cell-part structures such as axon tracts, acellular anatomical structures such as hair, and organism subdivisions such as head. Excluded is the whole organism and more granular parts of the organism, such as atoms, molecules, macromolecular complexes and cells. " ; obo:IAO_0000117 ; obo:IAO_creation_date "10.7.2011" ; oboInOwl:inSubset caro:plus ; a owl:Class ; rdfs:label "gross anatomical part"@en ; rdfs:subClassOf obo:CARO_0000006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CARO_0000012 ] ; owl:equivalentClass [ a owl:Class ; owl:unionOf (obo:CARO_0000004 obo:CARO_0000032 obo:CARO_0000040 obo:CARO_0000042 obo:CARO_0001000 obo:CARO_0010000 ) ] . obo:CARO_0001010 obo:IAO_0000115 "Material anatomical entity that is a member of an individual species or is a viral or viroid particle." ; obo:IAO_0000117 "Melissa Haendel" ; obo:IAO_creation_date "9/18/11" ; oboInOwl:hasExactSynonym "organism or virus or viroid" ; a owl:Class ; rdfs:label "organism" ; rdfs:subClassOf obo:BFO_0000040 . obo:CARO_0010000 obo:IAO_0000115 "An anatomical structure that has more than one cell as a part." ; obo:IAO_0000117 "djs93" ; obo:IAO_creation_date "Sun Feb 27 10:53:00 GMT 2011" ; oboInOwl:id "CARO:0010000" ; oboInOwl:inSubset caro:core ; a owl:Class ; rdfs:label "multicellular anatomical structure" ; rdfs:subClassOf obo:CARO_0000003, obo:CARO_0001008, _:genid428 ; owl:equivalentClass _:genid414 . obo:CARO_0010004 obo:IAO_0000115 "An individual member of a clade of cellular organisms." ; obo:IAO_0000117 ; obo:IAO_creation_date "7.16.2011" ; oboInOwl:id "CARO:0010004" ; a owl:Class ; rdfs:comment "A general term for organism that is agnostic about single cell vs multi-cellular. Note that this is a subclass of 'anatomical structure', meaning that an organism must be a connected structure. For example, if I take one plant and make a rooted cutting from a it, I now have two (clonally related) organisms. " ; rdfs:label "cellular organism" ; rdfs:subClassOf obo:CARO_0000003, obo:CARO_0001010 . obo:CARO_0020000 obo:IAO_0000115 "Material anatomical entity consisting of multiple anatomical structures that are not connected to each other." ; oboInOwl:id "CARO:0000054" ; oboInOwl:inSubset caro:core ; a owl:Class ; rdfs:label "disconnected anatomical group" ; rdfs:subClassOf obo:CARO_0000006, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0010001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002180 ; owl:someValuesFrom obo:CARO_0000003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CARO_0000006 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0010001 ] [ a owl:Restriction ; owl:minQualifiedCardinality "2"^^xsd:nonNegativeInteger ; owl:onClass obo:CARO_0000003 ; owl:onProperty obo:RO_0002180 ] ) ] . obo:CARO_0020003 obo:IAO_0000115 "An anatomical structure consisting of one or more cells." ; oboInOwl:created_by ; oboInOwl:creation_date "2018-09-28T14:20:19Z"^^xsd:dateTime ; a owl:Class ; rdfs:label "cellular anatomical structure"@en ; rdfs:subClassOf obo:CARO_0000006 ; owl:equivalentClass _:genid428 . obo:CARO_0030000 obo:IAO_0000115 "Entity that is, is part of, or derived from an organism, virus, or viroid or a collection of them." ; a owl:Class ; rdfs:comment "Important for alignment with Darwin Core class \"Organism\"." ; rdfs:label "biological entity" ; rdfs:subClassOf obo:BFO_0000004 . obo:CHEBI_10545 obo:IAO_0000115 "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." ; chebi:charge "-1" ; chebi:mass "0.000548579903" ; chebi:monoisotopicmass "0.0" ; oboInOwl:hasDbXref "KEGG:C05359", "PMID:21614077", "Wikipedia:Electron" ; oboInOwl:hasExactSynonym "electron" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Elektron", "beta", "beta(-)", "beta-particle", "e", "e(-)", "e-", "negatron" ; oboInOwl:id "CHEBI:10545" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "electron" ; rdfs:subClassOf obo:CHEBI_36338 . obo:CHEBI_131604 obo:IAO_0000115 "Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Mycoplasma genitalium metabolites" ; oboInOwl:id "CHEBI:131604" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "Mycoplasma genitalium metabolite" ; rdfs:subClassOf obo:CHEBI_76969 . obo:CHEBI_131927 obo:IAO_0000115 "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dicarboxylic acids and derivatives" ; oboInOwl:id "CHEBI:131927" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dicarboxylic acids and O-substituted derivatives" ; rdfs:subClassOf obo:CHEBI_36586 . obo:CHEBI_132153 obo:IAO_0000115 "A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "(C14H20NO11)n.H2O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hyaluronan", "hyaluronate polyanion" ; oboInOwl:id "CHEBI:132153" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hyaluronate" ; rdfs:subClassOf obo:CHEBI_61469, obo:CHEBI_63551, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16336 ] . obo:CHEBI_132717 obo:IAO_0000115 "A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties." ; oboInOwl:hasDbXref "Wikipedia:Bleach" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:132717" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bleaching agent" ; rdfs:subClassOf obo:CHEBI_33893 . obo:CHEBI_132992 obo:IAO_0000115 "A drug that makes increases the sensitivity of tumour cells to radiation therapy." ; oboInOwl:hasDbXref "PMID:12520460", "Wikipedia:Radiosensitizer" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "radiosensitiser", "radiosensitisers", "radiosensitising agent", "radiosensitising agents", "radiosensitizer", "radiosensitizers", "radiosensitizing agents" ; oboInOwl:id "CHEBI:132992" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "radiosensitizing agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_134179 obo:IAO_0000115 "Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa." ; oboInOwl:hasDbXref "Wikipedia:Volatile_organic_compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "VOC", "VOCs", "volatile organic compounds" ; oboInOwl:id "CHEBI:134179" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "volatile organic compound" ; rdfs:subClassOf obo:CHEBI_72695 . obo:CHEBI_134249 obo:IAO_0000115 "An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups." ; chebi:charge "-1" ; chebi:formula "CH2O3SR" ; chebi:mass "94.091" ; chebi:monoisotopicmass "93.97246" ; chebi:smiles "C(S([O-])(=O)=O)*" ; oboInOwl:hasAlternativeId "CHEBI:22318" ; oboInOwl:hasDbXref "MetaCyc:Alkanesulfonates" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkanesulfonate oxoanions", "alkanesulfonates", "an alkanesulfonate" ; oboInOwl:id "CHEBI:134249" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkanesulfonate oxoanion" ; rdfs:subClassOf obo:CHEBI_33554 . obo:CHEBI_136859 obo:IAO_0000115 "A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent." ; oboInOwl:hasDbXref "PMID:26449612" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pro-agents", "proagent", "proagents" ; oboInOwl:id "CHEBI:136859" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pro-agent" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_136889 obo:IAO_0000115 "Any steroid that has beta-configuration at position 5." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5beta steroids", "5beta-steroid", "5beta-steroids" ; oboInOwl:id "CHEBI:136889" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "5beta steroid" ; rdfs:subClassOf obo:CHEBI_35341 . obo:CHEBI_137041 obo:IAO_0000115 "The monoprotonated form of quinine, the predominant species at pH7.3." ; chebi:charge "+1" ; chebi:formula "C20H25N2O2" ; chebi:inchi "InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/p+1/t13-,14-,19-,20+/m0/s1" ; chebi:inchikey "LOUPRKONTZGTKE-WZBLMQSHSA-O" ; chebi:mass "325.42470" ; chebi:monoisotopicmass "325.19105" ; chebi:smiles "[H][C@]1(C[C@@H]2CC[N@H+]1C[C@@H]2C=C)[C@H](O)c1ccnc2ccc(OC)cc12" ; oboInOwl:hasExactSynonym "(9R)-9-hydroxy-6'-methoxy-8alpha-cinchonan-1-ium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "quinine" ; oboInOwl:id "CHEBI:137041" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "quinine(1+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_51323, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_51371 ], [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_59138 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15854 ] . obo:CHEBI_137980 obo:IAO_0000115 "An atom of an element that exhibits properties that are between those of metals and nonmetals, or that has a mixture of them. The term generally includes boron, silicon, germanium, arsenic, antimony, and tellurium, while carbon, aluminium, selenium, polonium, and astatine are less commonly included." ; oboInOwl:hasDbXref "Wikipedia:Metalloid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metalloid", "metalloids" ; oboInOwl:id "CHEBI:137980" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "metalloid atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_137982 obo:IAO_0000115 "An organic cation obtained by protonation of the amino group of any tertiary amino compound." ; chebi:charge "+1" ; chebi:formula "HNR3" ; chebi:mass "15.015" ; chebi:monoisotopicmass "15.01090" ; chebi:smiles "[NH+](*)(*)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a tertiary amine", "tertiary amine(1+)", "tertiary ammonium ions" ; oboInOwl:id "CHEBI:137982" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tertiary ammonium ion" ; rdfs:subClassOf obo:CHEBI_25697, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_50996 ] . obo:CHEBI_138000 obo:IAO_0000115 "An N-alkylpyrrolidine that consists of N-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2." ; chebi:charge "0" ; chebi:formula "C10H14N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3" ; chebi:inchikey "SNICXCGAKADSCV-UHFFFAOYSA-N" ; chebi:mass "162.232" ; chebi:monoisotopicmass "162.11570" ; chebi:smiles "C=1C=C(C2N(CCC2)C)C=NC1" ; oboInOwl:hasExactSynonym "3-(1-methylpyrrolidin-2-yl)pyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:138000" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "3-(1-methylpyrrolidin-2-yl)pyridine" ; rdfs:subClassOf obo:CHEBI_26416, obo:CHEBI_26456, obo:CHEBI_46775 . obo:CHEBI_138015 obo:IAO_0000115 "Any compound that can disrupt the functions of the endocrine (hormone) system" ; oboInOwl:hasDbXref "PMID:27929035", "PMID:28356401", "PMID:28526231", "Wikipedia:Endocrine_disruptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "endocrine disrupting chemical", "endocrine disrupting chemicals", "endocrine disrupting compound", "endocrine disrupting compounds", "endocrine disruptors", "endocrine-disrupting chemical", "endocrine-disrupting chemicals", "hormonally active agent", "hormonally active agents" ; oboInOwl:id "CHEBI:138015" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "endocrine disruptor" ; rdfs:subClassOf obo:CHEBI_51061 . obo:CHEBI_138103 obo:IAO_0000115 "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." ; oboInOwl:hasDbXref "Wikipedia:Mineral_acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic acids", "mineral acid", "mineral acids" ; oboInOwl:id "CHEBI:138103" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic acid" ; rdfs:subClassOf obo:CHEBI_39141 . obo:CHEBI_138366 obo:IAO_0000115 "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:138366" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bile acids" ; rdfs:subClassOf obo:CHEBI_25384, obo:CHEBI_35350, obo:CHEBI_36078 . obo:CHEBI_138675 obo:IAO_0000115 "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." ; oboInOwl:hasDbXref "Wikipedia:https://en.wikipedia.org/wiki/Gas" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gas molecular entities", "gaseous molecular entities", "gaseous molecular entity" ; oboInOwl:id "CHEBI:138675" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "gas molecular entity" ; rdfs:subClassOf obo:CHEBI_33579 . obo:CHEBI_13941 chebi:charge "-1" ; chebi:formula "CH2NO2" ; chebi:inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1" ; chebi:inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-M" ; chebi:mass "60.03212" ; chebi:monoisotopicmass "60.00910" ; chebi:smiles "NC([O-])=O" ; oboInOwl:hasDbXref "Beilstein:3903503", "CAS:302-11-4", "Gmelin:239604" ; oboInOwl:hasExactSynonym "carbamate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Carbamat", "Karbamat", "carbamate ion", "carbamic acid, ion(1-)" ; oboInOwl:id "CHEBI:13941" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbamate" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_28616 ] . obo:CHEBI_139588 obo:IAO_0000115 "An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety." ; oboInOwl:hasDbXref "PMID:15326516", "PMID:19908854", "PMID:20382022", "PMID:23295224" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-hydroxy ketones", "alpha-hydroxy-ketone", "alpha-hydroxy-ketones", "alpha-hydroxyketone", "alpha-hydroxyketones" ; oboInOwl:id "CHEBI:139588" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-hydroxy ketone" ; rdfs:subClassOf obo:CHEBI_30879, obo:CHEBI_52396 . obo:CHEBI_139592 obo:IAO_0000115 "An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups." ; chebi:charge "0" ; chebi:formula "C2HO2R3" ; chebi:mass "57.028" ; chebi:monoisotopicmass "56.99765" ; chebi:smiles "C(C(=O)*)(O)(*)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tertiary alpha-hydroxy ketones", "tertiary alpha-hydroxy-ketone", "tertiary alpha-hydroxy-ketones", "tertiary alpha-hydroxyketone", "tertiary alpha-hydroxyketones" ; oboInOwl:id "CHEBI:139592" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tertiary alpha-hydroxy ketone" ; rdfs:subClassOf obo:CHEBI_139588, obo:CHEBI_26878 . obo:CHEBI_140601 obo:IAO_0000115 "Any saturated fatty acid containing 4 carbons." ; chebi:charge "0" ; chebi:formula "CHO2R" ; chebi:mass "45.017" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "*C(O)=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:140601" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fatty acid 4:0" ; rdfs:subClassOf obo:CHEBI_26666, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_78115 ] . obo:CHEBI_142163 obo:IAO_0000115 "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22." ; chebi:charge "0" ; chebi:formula "C7H6N2O" ; chebi:mass "134.136" ; chebi:monoisotopicmass "134.04801" ; chebi:smiles "C(=CC(NC(=*)*)=*)(NC(C(C)=*)=O)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:142163" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "24G7 epitope" ; rdfs:subClassOf obo:CHEBI_24433, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_53000 ] . obo:CHEBI_142355 obo:IAO_0000115 "A purine ribonucleoside that is a purine derivative attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage." ; chebi:charge "0" ; chebi:formula "C10H11N4O4R2" ; chebi:mass "251.219" ; chebi:monoisotopicmass "251.07803" ; chebi:smiles "C1(=*)NC(=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a purine D-ribonucleoside" ; oboInOwl:id "CHEBI:142355" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purines D-ribonucleoside" ; rdfs:subClassOf obo:CHEBI_26399, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_26386 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_47013 ] . obo:CHEBI_142513 obo:IAO_0000115 "A organic ion resulting from the deprotonation of the hydroxy group of any oxime." ; chebi:charge "-1" ; chebi:formula "CNO" ; chebi:mass "42.017" ; chebi:monoisotopicmass "41.99799" ; chebi:smiles "C(*)(=N[O-])*" ; oboInOwl:hasExactSynonym "oxime anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oximate", "oximates", "oxime anions" ; oboInOwl:id "CHEBI:142513" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxime anion" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_25750 ] . obo:CHEBI_145798 obo:IAO_0000115 "An organic anion that is the conjugate base of ouabain resulting from the deprotonation of the furanone moiety; major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C29H43O12" ; chebi:inchi "InChI=1S/C29H43O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,11,13,15-19,21-25,30-32,34-38H,3-6,8-10,12H2,1-2H3/q-1/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1" ; chebi:inchikey "MPLJNVZJPLASQC-HBYQJFLCSA-N" ; chebi:mass "583.652" ; chebi:monoisotopicmass "583.27600" ; chebi:smiles "O1[C@H]([C@@H]([C@H]([C@H]([C@@H]1O[C@H]2C[C@H]([C@]3([C@@](C2)(CC[C@]4([C@]5(CC[C@@H]([C@]5(C[C@H]([C@]34[H])O)C)C=6[CH-]OC(C6)=O)O)[H])O)CO)O)O)O)O)C" ; oboInOwl:hasDbXref "PMID:31075189", "PMID:31087249", "PMID:31170971", "PMID:32326025", "PMID:32368275", "PMID:32488807", "PMID:32651756" ; oboInOwl:hasExactSynonym "1beta,5,11alpha,14,19-pentahydroxy-17beta-(5-oxo-2,5-dihydrofuran-2-id-3-yl)-5beta,14beta-androstan-3beta-yl 6-deoxy-alpha-L-mannopyranoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ouabain", "ouabain anion" ; oboInOwl:id "CHEBI:145798" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ouabain(1-)" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_472805 ] . obo:CHEBI_146270 obo:IAO_0000115 "Any substance that produces or enhances dream-like states of consciousness." ; oboInOwl:hasDbXref "Wikipedia:Oneirogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oneirogens" ; oboInOwl:id "CHEBI:146270" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oneirogen" ; rdfs:subClassOf obo:CHEBI_35471 . obo:CHEBI_149484 obo:IAO_0000115 "A quinolinium ion obtained by protonation of the quinoline nitrogen and tertiary amino group of the antimalarial drug chloroquine. It is the major species at pH 7.3." ; chebi:charge "+2" ; chebi:formula "C18H28ClN3" ; chebi:inchi "InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)/p+2" ; chebi:inchikey "WHTVZRBIWZFKQO-UHFFFAOYSA-P" ; chebi:mass "321.890" ; chebi:monoisotopicmass "321.19608" ; chebi:smiles "[NH+]1=CC=C(C=2C1=CC(Cl)=CC2)NC(CCC[NH+](CC)CC)C" ; oboInOwl:hasDbXref "PMID:25693996" ; oboInOwl:hasExactSynonym "7-chloro-4-{[5-(diethylazaniumyl)pentan-2-yl]amino}quinolinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chloroquine dication", "di-protonated chloroquine" ; oboInOwl:id "CHEBI:149484" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chloroquine(2+)" ; rdfs:subClassOf obo:CHEBI_137982, obo:CHEBI_52837, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_3638 ] . obo:CHEBI_149548 obo:IAO_0000115 "An ammonium ion derivative obtained from protonation of the nitrogens of emetine. It is the major species at pH 7.3." ; chebi:charge "+2" ; chebi:formula "C29H42N2O4" ; chebi:inchi "InChI=1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/p+2/t18-,21-,24+,25-/m0/s1" ; chebi:inchikey "AUVVAXYIELKVAI-CKBKHPSWSA-P" ; chebi:mass "482.664" ; chebi:monoisotopicmass "482.31336" ; chebi:smiles "C=1C(=C(C=C2C1CC[NH+]3C[C@@H]([C@@](C[C@@]23[H])([H])C[C@@]4([H])[NH2+]CCC=5C4=CC(=C(C5)OC)OC)CC)OC)OC" ; oboInOwl:hasDbXref "MetaCyc:CPD-14817", "PMID:5985282" ; oboInOwl:hasExactSynonym "(2S)-6',7',10,11-tetramethoxyemetan-2',5-diium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "emetine dication" ; oboInOwl:id "CHEBI:149548" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "emetine(2+)" ; rdfs:subClassOf obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_4781 ] . obo:CHEBI_149552 obo:IAO_0000115 "Any agent that induces nausea and vomiting." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "emetics" ; oboInOwl:id "CHEBI:149552" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "emetic" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_149553 obo:IAO_0000115 "Any antiviral agent which inhibits the activity of coronaviruses." ; oboInOwl:hasDbXref "Wikipedia:Coronavirus" ; oboInOwl:hasExactSynonym "anticoronaviral agent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-coronaviral agent", "anti-coronaviral agents", "anti-coronavirus agent", "anti-coronavirus agents", "anticoronaviral agents", "anticoronaviral drug", "anticoronaviral drugs", "anticoronavirus agent", "anticoronavirus agents", "anticoronviral agent", "anticoronviral agents" ; oboInOwl:id "CHEBI:149553" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anticoronaviral agent" ; rdfs:subClassOf obo:CHEBI_22587 . obo:CHEBI_15138 obo:IAO_0000115 "A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide." ; chebi:charge "-2" ; chebi:formula "S" ; chebi:inchi "InChI=1S/S/q-2" ; chebi:inchikey "UCKMPCXJQFINFW-UHFFFAOYSA-N" ; chebi:mass "32.06600" ; chebi:monoisotopicmass "31.97317" ; chebi:smiles "[S--]" ; oboInOwl:hasDbXref "CAS:18496-25-8", "UM-BBD_compID:c0569" ; oboInOwl:hasExactSynonym "sulfanediide", "sulfide(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "S(2-)", "Sulfide", "sulphide" ; oboInOwl:id "CHEBI:15138" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfide(2-)" ; rdfs:subClassOf obo:CHEBI_79388, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29919 ] . obo:CHEBI_15318 obo:IAO_0000115 "A purine nucleobase found in humans and other organisms." ; chebi:charge "0" ; chebi:formula "C5H4N4O2" ; chebi:mass "152.111" ; chebi:monoisotopicmass "152.03343" ; oboInOwl:hasDbXref "ECMDB:ECMDB00292", "KNApSAcK:C00019660", "PMID:1557408", "PMID:24629268", "PMID:9007687", "YMDB:YMDB00263" ; oboInOwl:hasExactSynonym "xanthine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,6-dioxopurine", "2,6-dioxopurines", "xanthines" ; oboInOwl:id "CHEBI:15318" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "xanthine" ; rdfs:subClassOf obo:CHEBI_25810, obo:CHEBI_26386, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16235 ] . obo:CHEBI_15339 obo:IAO_0000115 "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." ; oboInOwl:hasAlternativeId "CHEBI:13699", "CHEBI:2377" ; oboInOwl:hasDbXref "KEGG:C00028", "KEGG:C16722" ; oboInOwl:hasExactSynonym "Acceptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "A", "Akzeptor", "Hydrogen-acceptor", "Oxidized donor", "accepteur" ; oboInOwl:id "CHEBI:15339" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acceptor" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_15347 obo:IAO_0000115 "A methyl ketone that consists of propane bearing an oxo group at C2." ; chebi:charge "0" ; chebi:formula "C3H6O" ; chebi:inchi "InChI=1S/C3H6O/c1-3(2)4/h1-2H3" ; chebi:inchikey "CSCPPACGZOOCGX-UHFFFAOYSA-N" ; chebi:mass "58.07914" ; chebi:monoisotopicmass "58.04186" ; chebi:smiles "CC(C)=O" ; oboInOwl:hasAlternativeId "CHEBI:13708", "CHEBI:22182", "CHEBI:2398", "CHEBI:40571" ; oboInOwl:hasDbXref "Beilstein:635680", "CAS:67-64-1", "Gmelin:1466", "HMDB:HMDB0001659", "KEGG:C00207", "KEGG:D02311", "LIPID_MAPS_instance:LMFA12000057", "MetaCyc:ACETONE", "PDBeChem:ACN", "PMID:17190852", "PMID:17347819", "Reaxys:635680", "UM-BBD_compID:c0556", "Wikipedia:Acetone" ; oboInOwl:hasExactSynonym "ACETONE", "Acetone", "acetone", "propan-2-one" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-Propanone", "Aceton", "Azeton", "Dimethyl ketone", "Dimethylketon", "Propanon", "Pyroacetic ether", "beta-Ketopropane", "dimethylcetone", "dimethylketone", "methyl ketone", "propanone" ; oboInOwl:id "CHEBI:15347" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acetone" ; rdfs:subClassOf obo:CHEBI_134179, obo:CHEBI_26292, obo:CHEBI_51867, obo:CHEBI_73693, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48358 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77941 ] . obo:CHEBI_15355 obo:IAO_0000115 "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." ; chebi:charge "+1" ; chebi:formula "C7H16NO2" ; chebi:inchi "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1" ; chebi:inchikey "OIPILFWXSMYKGL-UHFFFAOYSA-N" ; chebi:mass "146.20748" ; chebi:monoisotopicmass "146.11756" ; chebi:smiles "CC(=O)OCC[N+](C)(C)C" ; oboInOwl:hasAlternativeId "CHEBI:12686", "CHEBI:13715", "CHEBI:22197", "CHEBI:2416", "CHEBI:40559" ; oboInOwl:hasDbXref "Beilstein:1764436", "CAS:51-84-3", "DrugBank:DB03128", "Drug_Central:65", "Gmelin:326108", "KEGG:C01996", "LINCS:LSM-5888", "PDBeChem:ACH", "PMID:14764638", "PMID:15014918", "PMID:15231705", "PMID:15361288", "PMID:18050502", "PMID:18407448", "PMID:19255787", "PMID:20963497", "PMID:21130809", "PMID:21246223", "PMID:21545631", "PMID:21601579", "Wikipedia:Acetylcholine" ; oboInOwl:hasExactSynonym "2-acetyloxy-N,N,N-trimethylethanaminium", "ACETYLCHOLINE", "Acetylcholine", "acetylcholine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ACh", "Azetylcholin", "C7H16NO2", "CC(=O)OCC[N+](C)(C)C", "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1", "InChIKey=OIPILFWXSMYKGL-UHFFFAOYSA-N", "O-Acetylcholine", "choline acetate" ; oboInOwl:id "CHEBI:15355" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acetylcholine" ; rdfs:subClassOf obo:CHEBI_35287, obo:CHEBI_47622, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24621 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25512 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38325 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ] . obo:CHEBI_15356 obo:IAO_0000115 "A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3." ; chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "NC(CS)C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:14061", "CHEBI:23508", "CHEBI:4050" ; oboInOwl:hasDbXref "Beilstein:1721406", "CAS:3374-22-9", "Gmelin:2933", "KEGG:C00736", "KNApSAcK:C00001351", "KNApSAcK:C00007323", "PMID:17439666", "PMID:25181601", "Reaxys:1721406", "Wikipedia:Cysteine" ; oboInOwl:hasExactSynonym "Cysteine", "cysteine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-Amino-3-mercaptopropionic acid", "2-amino-3-mercaptopropanoic acid", "2-amino-3-sulfanylpropanoic acid", "C", "Cys", "Cystein", "Hcys", "Zystein", "cisteina" ; oboInOwl:id "CHEBI:15356" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cysteine" ; rdfs:subClassOf obo:CHEBI_26167, obo:CHEBI_26834, obo:CHEBI_33704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50326 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32456 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32458 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35237 ] . obo:CHEBI_15366 obo:IAO_0000115 "A simple monocarboxylic acid containing two carbons." ; chebi:charge "0" ; chebi:formula "C2H4O2" ; chebi:inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)" ; chebi:inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-N" ; chebi:mass "60.05200" ; chebi:monoisotopicmass "60.02113" ; chebi:smiles "CC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:22169", "CHEBI:2387", "CHEBI:40486" ; oboInOwl:hasDbXref "Beilstein:506007", "CAS:64-19-7", "Drug_Central:4211", "Gmelin:1380", "HMDB:HMDB0000042", "KEGG:C00033", "KEGG:D00010", "KNApSAcK:C00001176", "LIPID_MAPS_instance:LMFA01010002", "MetaCyc:ACET", "PDBeChem:ACT", "PDBeChem:ACY", "PMID:12005138", "PMID:15107950", "PMID:16630552", "PMID:16774200", "PMID:17190852", "PMID:19416101", "PMID:19469536", "PMID:22153255", "PMID:22173419", "PPDB:1333", "Reaxys:506007", "Wikipedia:Acetic_acid" ; oboInOwl:hasExactSynonym "ACETIC ACID", "Acetic acid", "acetic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "AcOH", "CH3-COOH", "CH3CO2H", "E 260", "E-260", "E260", "Essigsaeure", "Ethanoic acid", "Ethylic acid", "HOAc", "INS No. 260", "MeCO2H", "MeCOOH", "Methanecarboxylic acid", "acide acetique", "ethoic acid" ; oboInOwl:id "CHEBI:15366" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acetic acid" ; rdfs:subClassOf obo:CHEBI_25384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48356 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64049 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_65256 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30089 ] . obo:CHEBI_15379 chebi:charge "0" ; chebi:formula "O2" ; chebi:inchi "InChI=1S/O2/c1-2" ; chebi:inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-N" ; chebi:mass "31.998" ; chebi:monoisotopicmass "31.98983" ; chebi:smiles "O=O" ; oboInOwl:hasAlternativeId "CHEBI:10745", "CHEBI:13416", "CHEBI:23833", "CHEBI:25366", "CHEBI:30491", "CHEBI:44742", "CHEBI:7860" ; oboInOwl:hasDbXref "CAS:7782-44-7", "Gmelin:485", "HMDB:HMDB0001377", "KEGG:C00007", "KEGG:D00003", "MetaCyc:OXYGEN-MOLECULE", "MolBase:750", "PDBeChem:OXY", "PMID:10906528", "PMID:16977326", "PMID:18210929", "PMID:18638417", "PMID:19840863", "PMID:7710549", "PMID:9463773", "Wikipedia:Oxygen" ; oboInOwl:hasExactSynonym "dioxygen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Disauerstoff", "E 948", "E-948", "E948", "O2", "OXYGEN MOLECULE", "Oxygen", "[OO]", "dioxygene", "molecular oxygen" ; oboInOwl:id "CHEBI:15379" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dioxygen" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_25362, obo:CHEBI_33263, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33893 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35472 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63248 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77974 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29793 ] . obo:CHEBI_15422 obo:IAO_0000115 "An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways." ; chebi:charge "0" ; chebi:formula "C10H16N5O13P3" ; chebi:inchi "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "ZKHQWZAMYRWXGA-KQYNXXCUSA-N" ; chebi:mass "507.18100" ; chebi:monoisotopicmass "506.99575" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:10789", "CHEBI:10841", "CHEBI:13236", "CHEBI:22249", "CHEBI:2359", "CHEBI:40938" ; oboInOwl:hasDbXref "Beilstein:73010", "CAS:56-65-5", "DrugBank:DB00171", "Drug_Central:91", "Gmelin:34857", "HMDB:HMDB0000538", "KEGG:C00002", "KEGG:D08646", "KNApSAcK:C00001491", "PDBeChem:ATP", "Patent:US3079379", "Reaxys:73010", "Wikipedia:Adenosine_triphosphate" ; oboInOwl:hasExactSynonym "ATP", "adenosine 5'-(tetrahydrogen triphosphate)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ADENOSINE-5'-TRIPHOSPHATE", "Adenosine 5'-triphosphate", "Adenosine triphosphate", "H4atp" ; oboInOwl:id "CHEBI:15422" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ATP" ; rdfs:subClassOf obo:CHEBI_37045, obo:CHEBI_37096, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50733 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_57299 ] . obo:CHEBI_155837 obo:IAO_0000115 "A peptide zwitterion obtained from the tranfer of a proton from the carboxy group to the amino group of any tripeptide. It contains an equal number of positively-charged and negatively-charged functional groups. Major structure at pH 7.3." ; chebi:charge "0" ; chebi:formula "C6H8N3O4R3" ; chebi:mass "186.146" ; chebi:monoisotopicmass "186.05148" ; chebi:smiles "C(=O)([C@@H]([NH3+])*)N[C@H](C(=O)N[C@H](C(=O)[O-])*)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-amino acid tripeptide zwitterion", "L-amino acid tripeptide zwitterions", "amino acid tripeptide zwitterion", "amino acid tripeptide zwitterions", "an L-amino acid tripeptide" ; oboInOwl:id "CHEBI:155837" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tripeptide zwitterion" ; rdfs:subClassOf obo:CHEBI_60466, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_47923 ] . obo:CHEBI_15693 obo:IAO_0000115 "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals." ; chebi:charge "0" ; chebi:formula "C2H4O2(CH2O)n" ; oboInOwl:hasAlternativeId "CHEBI:13755", "CHEBI:22305", "CHEBI:2561" ; oboInOwl:hasDbXref "KEGG:C01370", "Wikipedia:Aldose" ; oboInOwl:hasExactSynonym "Aldose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldoses", "an aldose" ; oboInOwl:id "CHEBI:15693" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aldose" ; rdfs:subClassOf obo:CHEBI_35381 . obo:CHEBI_15705 obo:IAO_0000115 "Any alpha-amino acid having L-configuration at the alpha-carbon." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.05870" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "N[C@@H]([*])C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:13072", "CHEBI:13243", "CHEBI:13797", "CHEBI:21224", "CHEBI:6175" ; oboInOwl:hasDbXref "KEGG:C00151" ; oboInOwl:hasExactSynonym "L-alpha-amino acid", "L-alpha-amino acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-2-Amino acid", "L-Amino acid", "L-alpha-amino acids" ; oboInOwl:id "CHEBI:15705" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-alpha-amino acid" ; rdfs:subClassOf obo:CHEBI_33704, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_59814 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_59869 ] . obo:CHEBI_15734 obo:IAO_0000115 "A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." ; chebi:charge "0" ; chebi:formula "CH3OR" ; chebi:mass "31.034" ; chebi:monoisotopicmass "31.01839" ; chebi:smiles "*C(O)([H])[H]" ; oboInOwl:hasAlternativeId "CHEBI:13676", "CHEBI:14887", "CHEBI:26262", "CHEBI:57489", "CHEBI:8406" ; oboInOwl:hasDbXref "KEGG:C00226" ; oboInOwl:hasExactSynonym "Primary alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-Alcohol", "a primary alcohol", "primary alcohols" ; oboInOwl:id "CHEBI:15734" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "primary alcohol" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_15740 obo:IAO_0000115 "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects." ; chebi:charge "-1" ; chebi:formula "CHO2" ; chebi:inchi "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1" ; chebi:inchikey "BDAGIHXWWSANSR-UHFFFAOYSA-M" ; chebi:mass "45.01744" ; chebi:monoisotopicmass "44.99820" ; chebi:smiles "[H]C([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:14276", "CHEBI:24081" ; oboInOwl:hasDbXref "Beilstein:1901205", "CAS:71-47-6", "Gmelin:1006", "HMDB:HMDB0000142", "KEGG:C00058", "MetaCyc:FORMATE", "PMID:17190852", "PMID:3946945", "Reaxys:1901205", "UM-BBD_compID:c0106", "Wikipedia:Formate" ; oboInOwl:hasExactSynonym "formate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HCO2 anion", "aminate", "formiate", "formic acid, ion(1-)", "formylate", "hydrogen carboxylate", "methanoate" ; oboInOwl:id "CHEBI:15740" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "formate" ; rdfs:subClassOf obo:CHEBI_35757, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_30751 ] . obo:CHEBI_15837 obo:IAO_0000115 "An primary alcohol that is butan-1-ol in which a hydrogen at position 3 has been replaced by a methyl group." ; chebi:charge "0" ; chebi:formula "C5H12O" ; chebi:inchi "InChI=1S/C5H12O/c1-5(2)3-4-6/h5-6H,3-4H2,1-2H3" ; chebi:inchikey "PHTQWCKDNZKARW-UHFFFAOYSA-N" ; chebi:mass "88.14818" ; chebi:monoisotopicmass "88.08882" ; chebi:smiles "CC(C)CCO" ; oboInOwl:hasAlternativeId "CHEBI:11855", "CHEBI:1597", "CHEBI:20125", "CHEBI:43359" ; oboInOwl:hasDbXref "Beilstein:1718835", "CAS:123-51-3", "DrugBank:DB02296", "Gmelin:49460", "HMDB:HMDB0006007", "KEGG:C07328", "PMID:23043843", "PMID:23698045", "PMID:24487533", "PMID:24767042", "PMID:24804072", "PMID:24862930", "Reaxys:1718835", "YMDB:YMDB00570" ; oboInOwl:hasExactSynonym "3-methylbutan-1-ol", "isoamylol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-HYDROXY-3-METHYLBUTANE", "2-methyl-4-butanol", "3-Methylbutanol", "3-methyl-1-butanol", "3-methylbutanol", "Iso-amylalkohol", "Isoamyl alcohol", "Isopentyl alcohol", "Isopentylalkohol", "alcool isoamylique", "i-amyl alcohol", "isobutylcarbinol", "isopentan-1-ol", "isopentanol", "primary isoamyl alcohol" ; oboInOwl:id "CHEBI:15837" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isoamylol" ; rdfs:subClassOf obo:CHEBI_134179, obo:CHEBI_15734, obo:CHEBI_50584, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35718 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76206 ], [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_30362 ] . obo:CHEBI_15841 obo:IAO_0000115 "A peptide containing ten or more amino acid residues." ; chebi:formula "C4H6N2O3R2(C2H2NOR)n" ; oboInOwl:hasAlternativeId "CHEBI:14860", "CHEBI:8314" ; oboInOwl:hasDbXref "KEGG:C00403" ; oboInOwl:hasExactSynonym "Polypeptide", "polypeptides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Polypeptid", "polipeptido" ; oboInOwl:id "CHEBI:15841" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polypeptide" ; rdfs:subClassOf obo:CHEBI_16670, obo:CHEBI_33839 . obo:CHEBI_15854 obo:IAO_0000115 "A cinchona alkaloid that is cinchonidine in which the hydrogen at the 6-position of the quinoline ring is substituted by methoxy." ; chebi:charge "0" ; chebi:formula "C20H24N2O2" ; chebi:inchi "InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1" ; chebi:inchikey "LOUPRKONTZGTKE-WZBLMQSHSA-N" ; chebi:mass "324.41680" ; chebi:monoisotopicmass "324.18378" ; chebi:smiles "[H][C@]1(C[C@@H]2CC[N@]1C[C@@H]2C=C)[C@H](O)c1ccnc2ccc(OC)cc12" ; oboInOwl:hasAlternativeId "CHEBI:127176", "CHEBI:15001", "CHEBI:26499", "CHEBI:355947", "CHEBI:569215", "CHEBI:602929", "CHEBI:8723" ; oboInOwl:hasDbXref "Beilstein:91867", "CAS:130-95-0", "DrugBank:DB00468", "Drug_Central:4523", "KEGG:C06526", "KEGG:D08460", "KNApSAcK:C00002193", "PMID:10821711", "PMID:10891117", "PMID:10937718", "PMID:11212126", "PMID:11549443", "PMID:11728183", "PMID:11844668", "PMID:11855978", "PMID:12127529", "PMID:12213073", "PMID:12217353", "PMID:12477351", "PMID:12502361", "PMID:12798326", "PMID:12873511", "PMID:14761192", "PMID:15026051", "PMID:15027870", "PMID:15225721", "PMID:15857133", "PMID:16524728", "PMID:16933872", "PMID:17482816", "PMID:17506538", "PMID:17570664", "PMID:17850126", "PMID:18348514", "PMID:18788725", "PMID:2579237", "PMID:2657065", "PMID:7009867", "PMID:8182707", "Wikipedia:Quinine" ; oboInOwl:hasExactSynonym "(9R)-6'-methoxy-8alpha-cinchonan-9-ol", "Quinine", "quinine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-Quinine", "(-)-quinine", "(8S,9R)-quinine", "(R)-(-)-quinine", "(R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol", "6'-methoxycinchonidine", "Chinin", "chinine", "chininum", "quinina" ; oboInOwl:id "CHEBI:15854" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "quinine" ; rdfs:subClassOf obo:CHEBI_51323, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35481 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_51371 ], [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_59138 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_137041 ] . obo:CHEBI_15858 chebi:charge "-1" ; chebi:formula "Br" ; chebi:inchi "InChI=1S/BrH/h1H/p-1" ; chebi:inchikey "CPELXLSAUQHCOX-UHFFFAOYSA-M" ; chebi:mass "79.90400" ; chebi:monoisotopicmass "78.91889" ; chebi:smiles "[Br-]" ; oboInOwl:hasAlternativeId "CHEBI:13918", "CHEBI:3178", "CHEBI:49515" ; oboInOwl:hasDbXref "Beilstein:3587179", "CAS:24959-67-9", "Gmelin:14908", "KEGG:C00720", "KEGG:C01324", "PDBeChem:BR" ; oboInOwl:hasExactSynonym "Bromide", "bromide", "bromide(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "BROMIDE ION", "Br(-)", "Br-", "bromine anion" ; oboInOwl:id "CHEBI:15858" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bromide" ; rdfs:subClassOf obo:CHEBI_16042, obo:CHEBI_36896, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_47266 ] . obo:CHEBI_15986 obo:IAO_0000115 "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." ; chebi:charge "0" ; chebi:formula "(C5H8O6PR)n.C10H17O10PR2" ; oboInOwl:hasAlternativeId "CHEBI:13672", "CHEBI:14859", "CHEBI:8312" ; oboInOwl:hasDbXref "KEGG:C00419" ; oboInOwl:hasExactSynonym "Polynucleotide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polynucleotides" ; oboInOwl:id "CHEBI:15986" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polynucleotide" ; rdfs:subClassOf obo:CHEBI_33695, obo:CHEBI_61120, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50319 ] . obo:CHEBI_16042 obo:IAO_0000115 "A monoatomic monoanion resulting from the addition of an electron to any halogen atom." ; chebi:charge "-1" ; chebi:formula "X" ; chebi:mass "0.0" ; chebi:monoisotopicmass "0.0" ; chebi:smiles "[*-]" ; oboInOwl:hasAlternativeId "CHEBI:14384", "CHEBI:5605" ; oboInOwl:hasDbXref "KEGG:C00462" ; oboInOwl:hasExactSynonym "halide ions" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HX", "Halide", "a halide anion", "halide anions", "halide(1-)", "halides", "halogen anion" ; oboInOwl:id "CHEBI:16042" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halide anion" ; rdfs:subClassOf obo:CHEBI_33429, obo:CHEBI_79389 . obo:CHEBI_16133 obo:IAO_0000115 "The simplest member of the class of cyclopentanols bearing a single hydroxy substituent. The parent of the class of cyclopentanols." ; chebi:charge "0" ; chebi:formula "C5H10O" ; chebi:inchi "InChI=1S/C5H10O/c6-5-3-1-2-4-5/h5-6H,1-4H2" ; chebi:inchikey "XCIXKGXIYUWCLL-UHFFFAOYSA-N" ; chebi:mass "86.13230" ; chebi:monoisotopicmass "86.07316" ; chebi:smiles "OC1CCCC1" ; oboInOwl:hasAlternativeId "CHEBI:14057", "CHEBI:23494", "CHEBI:4022" ; oboInOwl:hasDbXref "CAS:96-41-3", "KEGG:C02020", "MetaCyc:CYCLOPENTANOL", "PMID:22145629", "PMID:24273356", "Reaxys:1900556", "Wikipedia:Cyclopentanol" ; oboInOwl:hasExactSynonym "Cyclopentanol", "cyclopentanol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cyclopentyl alcohol", "Hydroxycyclopentane" ; oboInOwl:id "CHEBI:16133" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclopentanol" ; rdfs:subClassOf obo:CHEBI_23495 . obo:CHEBI_16134 obo:IAO_0000115 "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." ; chebi:charge "0" ; chebi:formula "H3N" ; chebi:inchi "InChI=1S/H3N/h1H3" ; chebi:inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-N" ; chebi:mass "17.03056" ; chebi:monoisotopicmass "17.02655" ; chebi:smiles "[H]N([H])[H]" ; oboInOwl:hasAlternativeId "CHEBI:13405", "CHEBI:13406", "CHEBI:13407", "CHEBI:13771", "CHEBI:22533", "CHEBI:44269", "CHEBI:44284", "CHEBI:44404", "CHEBI:7434" ; oboInOwl:hasDbXref "Beilstein:3587154", "CAS:7664-41-7", "Drug_Central:4625", "Gmelin:79", "HMDB:HMDB0000051", "KEGG:C00014", "KEGG:D02916", "KNApSAcK:C00007267", "MetaCyc:AMMONIA", "MolBase:930", "PDBeChem:NH3", "PMID:110589", "PMID:11139349", "PMID:11540049", "PMID:11746427", "PMID:11783653", "PMID:13753780", "PMID:14663195", "PMID:15092448", "PMID:15094021", "PMID:15554424", "PMID:15969015", "PMID:16008360", "PMID:16050680", "PMID:16348008", "PMID:16349403", "PMID:16614889", "PMID:16664306", "PMID:16842901", "PMID:17025297", "PMID:17439666", "PMID:17569513", "PMID:17737668", "PMID:18670398", "PMID:22002069", "PMID:22081570", "PMID:22088435", "PMID:22100291", "PMID:22130175", "PMID:22150211", "PMID:22240068", "PMID:22290316", "PMID:22342082", "PMID:22385337", "PMID:22443779", "PMID:22560242", "Reaxys:3587154", "Wikipedia:Ammonia" ; oboInOwl:hasExactSynonym "AMMONIA", "Ammonia", "ammonia", "azane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ammoniak", "NH3", "R-717", "[NH3]", "ammoniac", "amoniaco", "spirit of hartshorn" ; oboInOwl:id "CHEBI:16134" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ammonia" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_35107, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59740 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77941 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29337 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_28938 ] . obo:CHEBI_16136 obo:IAO_0000115 "A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen." ; chebi:charge "0" ; chebi:formula "H2S" ; chebi:inchi "InChI=1S/H2S/h1H2" ; chebi:inchikey "RWSOTUBLDIXVET-UHFFFAOYSA-N" ; chebi:mass "34.08188" ; chebi:monoisotopicmass "33.98772" ; chebi:smiles "[H]S[H]" ; oboInOwl:hasAlternativeId "CHEBI:13356", "CHEBI:14414", "CHEBI:24639", "CHEBI:43058", "CHEBI:45489", "CHEBI:5787" ; oboInOwl:hasDbXref "Beilstein:3535004", "CAS:7783-06-4", "Drug_Central:4260", "Gmelin:303", "KEGG:C00283", "KNApSAcK:C00007266", "MolBase:1709", "PDBeChem:H2S", "PMID:11788560", "PMID:14654297", "PMID:15003943", "PMID:15607739", "PMID:16446402", "PMID:18098324", "PMID:18524810", "PMID:18948540", "PMID:19695225", "PMID:22004989", "PMID:22378060", "PMID:22448627", "PMID:22473176", "PMID:22486842", "PMID:22520971", "PMID:22787557", "UM-BBD_compID:c0239", "Wikipedia:Hydrogen_sulfide" ; oboInOwl:hasExactSynonym "Hydrogen sulfide", "dihydridosulfur", "dihydrogen(sulfide)", "hydrogen sulfide", "sulfane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2S", "HYDROSULFURIC ACID", "Hydrogen-sulfide", "Schwefelwasserstoff", "Sulfide", "[SH2]", "acide sulfhydrique", "dihydrogen monosulfide", "dihydrogen sulfide", "hydrogen monosulfide", "hydrogen sulphide", "hydrogene sulfure", "sulfure d'hydrogene" ; oboInOwl:id "CHEBI:16136" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogen sulfide" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_33405, obo:CHEBI_33535, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27026 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_62488 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29919 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_30488 ] . obo:CHEBI_16183 obo:IAO_0000115 "A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC)." ; chebi:charge "0" ; chebi:formula "CH4" ; chebi:inchi "InChI=1S/CH4/h1H4" ; chebi:inchikey "VNWKTOKETHGBQD-UHFFFAOYSA-N" ; chebi:mass "16.04246" ; chebi:monoisotopicmass "16.03130" ; chebi:smiles "[H]C([H])([H])[H]" ; oboInOwl:hasAlternativeId "CHEBI:14585", "CHEBI:25220", "CHEBI:6811" ; oboInOwl:hasDbXref "Beilstein:1718732", "CAS:74-82-8", "Gmelin:59", "HMDB:HMDB0002714", "KEGG:C01438", "MetaCyc:CH4", "PMID:17791569", "PMID:23104415", "PMID:23353606", "PMID:23376302", "PMID:23397538", "PMID:23718889", "PMID:23739479", "PMID:23742231", "PMID:23756351", "PMID:24132456", "PMID:24161402", "PMID:24259373", "Patent:FR994032", "Patent:US2583090", "Reaxys:1718732", "UM-BBD_compID:c0095", "Wikipedia:Methane" ; oboInOwl:hasExactSynonym "Methane", "methane", "tetrahydridocarbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH4", "Methan", "marsh gas", "metano", "methyl hydride" ; oboInOwl:id "CHEBI:16183" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methane" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_18310, obo:CHEBI_37176, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35230 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76413 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76969 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29438 ] . obo:CHEBI_16189 obo:IAO_0000115 "A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid." ; chebi:charge "-2" ; chebi:formula "O4S" ; chebi:inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2" ; chebi:inchikey "QAOWNCQODCNURD-UHFFFAOYSA-L" ; chebi:mass "96.06360" ; chebi:monoisotopicmass "95.95283" ; chebi:smiles "[O-]S([O-])(=O)=O" ; oboInOwl:hasAlternativeId "CHEBI:15135", "CHEBI:45687", "CHEBI:9335" ; oboInOwl:hasDbXref "Beilstein:3648446", "CAS:14808-79-8", "Gmelin:2120", "HMDB:HMDB0001448", "KEGG:C00059", "KEGG:D05963", "MetaCyc:SULFATE", "PDBeChem:SO4", "PMID:11200094", "PMID:11452993", "PMID:11581495", "PMID:11798107", "PMID:12166931", "PMID:12668033", "PMID:14597181", "PMID:15093386", "PMID:15984785", "PMID:16186560", "PMID:16345535", "PMID:16347366", "PMID:16348007", "PMID:16483812", "PMID:16534979", "PMID:16656509", "PMID:16742508", "PMID:16742518", "PMID:17120760", "PMID:17420092", "PMID:17439666", "PMID:17709180", "PMID:18398178", "PMID:18815700", "PMID:18846414", "PMID:19047345", "PMID:19244483", "PMID:19544990", "PMID:19628332", "PMID:19812358", "PMID:30398859", "Reaxys:3648446", "Wikipedia:Sulfate" ; oboInOwl:hasExactSynonym "Sulfate", "sulfate", "tetraoxidosulfate(2-)", "tetraoxosulfate(2-)", "tetraoxosulfate(VI)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SO4(2-)", "SULFATE ION", "Sulfate anion(2-)", "Sulfate dianion", "Sulfate(2-)", "Sulfuric acid ion(2-)", "[SO4](2-)", "sulphate", "sulphate ion" ; oboInOwl:id "CHEBI:16189" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfate" ; rdfs:subClassOf obo:CHEBI_33482, obo:CHEBI_48154, obo:CHEBI_79388, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_45696 ] . obo:CHEBI_16199 obo:IAO_0000115 "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O)." ; chebi:charge "0" ; chebi:formula "CH4N2O" ; chebi:inchi "InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)" ; chebi:inchikey "XSQUKJJJFZCRTK-UHFFFAOYSA-N" ; chebi:mass "60.05534" ; chebi:monoisotopicmass "60.03236" ; chebi:smiles "NC(N)=O" ; oboInOwl:hasAlternativeId "CHEBI:15292", "CHEBI:27218", "CHEBI:46379", "CHEBI:9888" ; oboInOwl:hasDbXref "Beilstein:635724", "CAS:57-13-6", "DrugBank:DB03904", "Drug_Central:4264", "ECMDB:ECMDB04172", "Gmelin:1378", "HMDB:HMDB0000294", "KEGG:C00086", "KEGG:D00023", "KNApSAcK:C00007314", "MetaCyc:UREA", "PDBeChem:URE", "PMID:18037357", "PMID:22770225", "PPDB:1728", "Reaxys:635724", "UM-BBD_compID:c0165", "Wikipedia:Urea", "YMDB:YMDB00003" ; oboInOwl:hasExactSynonym "UREA", "Urea", "urea" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1728", "Carbamide", "E927b", "H2NC(O)NH2", "Harnstoff", "Karbamid", "carbamide", "carbonyldiamide", "ur", "uree" ; oboInOwl:id "CHEBI:16199" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "urea" ; rdfs:subClassOf obo:CHEBI_29347, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33287 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64577 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_28976 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_48376 ] . obo:CHEBI_16235 obo:IAO_0000115 "A 2-aminopurine carrying a 6-oxo substituent." ; chebi:charge "0" ; chebi:formula "C5H5N5O" ; chebi:inchi "InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)" ; chebi:inchikey "UYTPUPDQBNUYGX-UHFFFAOYSA-N" ; chebi:mass "151.126" ; chebi:monoisotopicmass "151.04941" ; chebi:smiles "C12=C(N=C(NC1=O)N)NC=N2" ; oboInOwl:hasAlternativeId "CHEBI:14371", "CHEBI:14372", "CHEBI:24443", "CHEBI:42948", "CHEBI:5563" ; oboInOwl:hasDbXref "Beilstein:147911", "CAS:73-40-5", "DrugBank:DB02377", "Gmelin:431879", "HMDB:HMDB0000132", "KEGG:C00242", "KNApSAcK:C00001501", "MetaCyc:GUANINE", "PDBeChem:GUN", "PMID:22770225", "PMID:8070089", "Reaxys:147911", "Wikipedia:Guanine" ; oboInOwl:hasExactSynonym "2-amino-1,9-dihydro-6H-purin-6-one", "GUANINE", "Guanine", "guanine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-Amino-6-hydroxypurine", "2-amino-6-oxopurine", "G", "Gua" ; oboInOwl:id "CHEBI:16235" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "guanine" ; rdfs:subClassOf obo:CHEBI_20702, obo:CHEBI_25810, obo:CHEBI_26386, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84735 ], [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_16236 obo:IAO_0000115 "A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group." ; chebi:charge "0" ; chebi:formula "C2H6O" ; chebi:inchi "InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3" ; chebi:inchikey "LFQSCWFLJHTTHZ-UHFFFAOYSA-N" ; chebi:mass "46.06844" ; chebi:monoisotopicmass "46.04186" ; chebi:smiles "CCO" ; oboInOwl:hasAlternativeId "CHEBI:14222", "CHEBI:23978", "CHEBI:30878", "CHEBI:30880", "CHEBI:42377", "CHEBI:44594", "CHEBI:4879" ; oboInOwl:hasDbXref "Beilstein:1718733", "CAS:64-17-5", "DrugBank:DB00898", "Drug_Central:1076", "Gmelin:787", "HMDB:HMDB0000108", "KEGG:C00469", "KEGG:D00068", "KEGG:D06542", "KNApSAcK:C00019560", "MetaCyc:ETOH", "MolBase:858", "MolBase:859", "PDBeChem:EOH", "PMID:11046114", "PMID:11090978", "PMID:11198720", "PMID:11200745", "PMID:11262320", "PMID:11303910", "PMID:11333032", "PMID:11505026", "PMID:11590970", "PMID:11728426", "PMID:11750186", "PMID:11754521", "PMID:11810019", "PMID:11826039", "PMID:11981228", "PMID:12824058", "PMID:12829422", "PMID:12888778", "PMID:12946583", "PMID:14674846", "PMID:15019421", "PMID:15239123", "PMID:15285839", "PMID:15464411", "PMID:15465973", "PMID:15749123", "PMID:15900217", "PMID:15902919", "PMID:16084479", "PMID:16133132", "PMID:16352430", "PMID:16390872", "PMID:16737463", "PMID:16891664", "PMID:16934862", "PMID:17043811", "PMID:17190852", "PMID:17663926", "PMID:17687877", "PMID:18095657", "PMID:18249266", "PMID:18320157", "PMID:18347649", "PMID:18408978", "PMID:18411066", "PMID:18456322", "PMID:18513832", "PMID:18922656", "PMID:18925476", "PMID:19280886", "PMID:19359288", "PMID:19384566", "PMID:19458312", "PMID:19851413", "PMID:19901811", "PMID:21600756", "PMID:21762181", "PMID:21881875", "PMID:21967628", "PMID:22019193", "PMID:22222864", "PMID:22261437", "PMID:22286266", "PMID:22306018", "PMID:22331491", "PMID:22336593", "PPDB:1373", "Reaxys:1718733", "UM-BBD_compID:c0038", "Wikipedia:Ethanol" ; oboInOwl:hasExactSynonym "ETHANOL", "Ethanol", "ethanol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-hydroxyethane", "Aethanol", "Aethylalkohol", "Alkohol", "C2H5OH", "Dehydrated ethanol", "EtOH", "Ethyl alcohol", "Methylcarbinol", "[CH2Me(OH)]", "[OEtH]", "alcohol", "alcohol etilico", "alcool ethylique", "etanol", "hydroxyethane", "spiritus vini" ; oboInOwl:id "CHEBI:16236" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ethanol" ; rdfs:subClassOf obo:CHEBI_134179, obo:CHEBI_23982, obo:CHEBI_50584, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35488 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48218 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48219 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48354 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_60643 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64018 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_52092 ] . obo:CHEBI_16240 obo:IAO_0000115 "An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond." ; chebi:charge "0" ; chebi:formula "H2O2" ; chebi:inchi "InChI=1S/H2O2/c1-2/h1-2H" ; chebi:inchikey "MHAJPDPJQMAIIY-UHFFFAOYSA-N" ; chebi:mass "34.01468" ; chebi:monoisotopicmass "34.00548" ; chebi:smiles "[H]OO[H]" ; oboInOwl:hasAlternativeId "CHEBI:13354", "CHEBI:13355", "CHEBI:24637", "CHEBI:44812", "CHEBI:5586" ; oboInOwl:hasDbXref "Beilstein:3587191", "CAS:7722-84-1", "Drug_Central:3281", "Gmelin:509", "HMDB:HMDB0003125", "KEGG:C00027", "KEGG:D00008", "MetaCyc:HYDROGEN-PEROXIDE", "MolBase:932", "PDBeChem:PEO", "PMID:10455187", "PMID:10557015", "PMID:10849784", "PMID:11033421", "PMID:11105916", "PMID:11318558", "PMID:11387393", "PMID:11809417", "PMID:11864786", "PMID:11893576", "PMID:12867293", "PMID:12934880", "PMID:14679422", "PMID:15028418", "PMID:15133946", "PMID:15298493", "PMID:16337875", "PMID:16463018", "PMID:16864869", "PMID:17020896", "PMID:17179007", "PMID:17610934", "PMID:17948137", "PMID:18179203", "PMID:18182702", "PMID:18306736", "PMID:18443210", "PMID:18592736", "PMID:19107210", "PMID:19229032", "PMID:19297450", "PMID:19509065", "PMID:26352695", "PMID:26365231", "PMID:7548021", "PMID:7581816", "PMID:8048546", "PMID:8375042", "PMID:8451754", "PMID:9051670", "PMID:9100841", "PMID:9168257", "PMID:9202721", "PMID:9558114", "PPDB:387", "Reaxys:3587191", "Wikipedia:Hydrogen_peroxide" ; oboInOwl:hasExactSynonym "HYDROGEN PEROXIDE", "Hydrogen peroxide", "bis(hydridooxygen)(O--O)", "dihydrogen peroxide", "dihydrogen(peroxide)", "dioxidane", "hydrogen peroxide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2O2", "HOOH", "Oxydol", "[OH(OH)]", "dihydrogen dioxide", "perhydrol" ; oboInOwl:id "CHEBI:16240" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogen peroxide" ; rdfs:subClassOf obo:CHEBI_24837, obo:CHEBI_26523, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_132717 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149552 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48219 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59163 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63490 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_65259 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_68495 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76967 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29192 ] . obo:CHEBI_16247 obo:IAO_0000115 "A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides." ; oboInOwl:hasAlternativeId "CHEBI:14816", "CHEBI:26063", "CHEBI:8150" ; oboInOwl:hasDbXref "KEGG:C00865" ; oboInOwl:hasExactSynonym "Phospholipid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a phospholipid derivative", "phospholipids" ; oboInOwl:id "CHEBI:16247" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phospholipid" ; rdfs:subClassOf obo:CHEBI_18059, obo:CHEBI_25703, obo:CHEBI_37734, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_62643 ] . obo:CHEBI_16335 obo:IAO_0000115 "A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond." ; chebi:charge "0" ; chebi:formula "C10H13N5O4" ; chebi:inchi "InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "OIRDTQYFTABQOQ-KQYNXXCUSA-N" ; chebi:mass "267.24152" ; chebi:monoisotopicmass "267.09675" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:13734", "CHEBI:22237", "CHEBI:2472", "CHEBI:40558", "CHEBI:40825", "CHEBI:40906" ; oboInOwl:hasDbXref "Beilstein:93029", "CAS:58-61-7", "DrugBank:DB00640", "Drug_Central:90", "ECMDB:ECMDB00050", "Gmelin:53385", "HMDB:HMDB0000050", "KEGG:C00212", "KEGG:D00045", "KNApSAcK:C00007444", "LINCS:LSM-28568", "MetaCyc:ADENOSINE", "PDBeChem:ADN", "PMID:11213237", "PMID:11820865", "PMID:11978011", "PMID:16183671", "PMID:16917093", "PMID:17190852", "PMID:18000974", "PMID:323854", "Reaxys:93029", "Wikipedia:Adenosine", "YMDB:YMDB00058" ; oboInOwl:hasExactSynonym "ADENOSINE", "Adenosine", "adenosine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol", "6-Amino-9-beta-D-ribofuranosyl-9H-purine", "9-beta-D-Ribofuranosidoadenine", "9-beta-D-Ribofuranosyl-9H-purin-6-amine", "9-beta-D-ribofuranosyl-9H-purin-6-amine", "Ade-Rib", "Adenine Deoxyribonucleoside", "Adenocard", "Adenocor", "Adenoscan", "Adenosin", "Adenyldeoxyriboside", "Ado", "Deoxyadenosine", "Desoxyadenosine", "beta-D-Adenosine" ; oboInOwl:id "CHEBI:16335" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adenosine" ; rdfs:subClassOf obo:CHEBI_142355, obo:CHEBI_22260, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35480 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38070 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ] . obo:CHEBI_16336 obo:IAO_0000115 "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells." ; chebi:charge "0" ; chebi:formula "(C14H21NO12)n" ; oboInOwl:hasAlternativeId "CHEBI:14412", "CHEBI:24622", "CHEBI:24623", "CHEBI:5772" ; oboInOwl:hasDbXref "Beilstein:8538277", "CAS:9004-61-9", "HMDB:HMDB0010366", "KEGG:C00518", "KEGG:D08043", "KEGG:G10505", "PMID:11122186", "PMID:18056362", "PMID:18290544", "Reaxys:8187837", "Wikipedia:Hyaluronan" ; oboInOwl:hasExactSynonym "Hyaluronic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Hyaluronsaeure", "[beta-D-glucopyranuronosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)]n", "[beta-N-Acetyl-D-glucosaminyl(1,4)beta-D-glucuronosyl(1,3)]n", "acide hyaluronique", "acido hialuronico", "hyaluronan" ; oboInOwl:id "CHEBI:16336" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hyaluronic acid" ; rdfs:subClassOf obo:CHEBI_37395, obo:CHEBI_72813, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_132153 ] . obo:CHEBI_16375 obo:IAO_0000115 "An optically active form of cysteine having D-configuration." ; chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "N[C@H](CS)C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:12919", "CHEBI:20921", "CHEBI:4111", "CHEBI:41887" ; oboInOwl:hasDbXref "Beilstein:1721407", "CAS:921-01-7", "DrugBank:DB03201", "ECMDB:ECMDB03417", "Gmelin:363236", "HMDB:HMDB0003417", "KEGG:C00793", "KNApSAcK:C00007323", "PDBeChem:DCY", "PMID:13761469", "PMID:23340406", "PMID:24800864", "Reaxys:1721407", "YMDB:YMDB00913" ; oboInOwl:hasExactSynonym "D-CYSTEINE", "D-Cysteine", "D-cysteine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2S)-2-amino-3-mercaptopropanoic acid", "(2S)-2-amino-3-sulfanylpropanoic acid", "(S)-2-amino-3-mercaptopropanoic acid", "D-Amino-3-mercaptopropionic acid", "D-Cystein", "D-Zystein", "DCY" ; oboInOwl:id "CHEBI:16375" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-cysteine" ; rdfs:subClassOf obo:CHEBI_15356, obo:CHEBI_16733, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32449 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32451 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_17561 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35236 ] . obo:CHEBI_16382 chebi:charge "-1" ; chebi:formula "I" ; chebi:inchi "InChI=1S/HI/h1H/p-1" ; chebi:inchikey "XMBWDFGMSWQBCA-UHFFFAOYSA-M" ; chebi:mass "126.90447" ; chebi:monoisotopicmass "126.90502" ; chebi:smiles "[I-]" ; oboInOwl:hasAlternativeId "CHEBI:14460", "CHEBI:49698", "CHEBI:5946" ; oboInOwl:hasDbXref "Beilstein:3587184", "CAS:20461-54-5", "Gmelin:14912", "KEGG:C00708", "PDBeChem:IOD" ; oboInOwl:hasExactSynonym "Iodide", "iodide", "iodide(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "I(-)", "I-", "IODIDE ION", "iodine anion" ; oboInOwl:id "CHEBI:16382" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iodide" ; rdfs:subClassOf obo:CHEBI_16042, obo:CHEBI_36897, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_43451 ] . obo:CHEBI_16385 obo:IAO_0000115 "Compounds having the structure RSR (R =/= H). Such compounds were once called thioethers." ; chebi:charge "0" ; chebi:formula "SR2" ; chebi:mass "32.066" ; chebi:monoisotopicmass "31.97207" ; oboInOwl:hasAlternativeId "CHEBI:13694", "CHEBI:26960", "CHEBI:9340" ; oboInOwl:hasDbXref "KEGG:C00297" ; oboInOwl:hasExactSynonym "sulfides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RSR", "Sulfide", "Thioether", "organic sulfides", "thioethers" ; oboInOwl:id "CHEBI:16385" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic sulfide" ; rdfs:subClassOf obo:CHEBI_26822, obo:CHEBI_33261 . obo:CHEBI_16526 obo:IAO_0000115 "A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food." ; chebi:charge "0" ; chebi:formula "CO2" ; chebi:inchi "InChI=1S/CO2/c2-1-3" ; chebi:inchikey "CURLTUGMZLYLDI-UHFFFAOYSA-N" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "O=C=O" ; oboInOwl:hasAlternativeId "CHEBI:13282", "CHEBI:13283", "CHEBI:13284", "CHEBI:13285", "CHEBI:23011", "CHEBI:3283", "CHEBI:48829" ; oboInOwl:hasDbXref "Beilstein:1900390", "CAS:124-38-9", "Drug_Central:4256", "Gmelin:989", "HMDB:HMDB0001967", "KEGG:C00011", "KEGG:D00004", "MetaCyc:CARBON-DIOXIDE", "MolBase:752", "PDBeChem:CO2", "PMID:10826146", "PMID:11094503", "PMID:11584085", "PMID:11802652", "PMID:14639145", "PMID:15050588", "PMID:16591971", "PMID:16656478", "PMID:16659660", "PMID:17190796", "PMID:17448243", "PMID:17878298", "PMID:17884085", "PMID:19043767", "PMID:19259576", "PMID:19854893", "PMID:23384758", "PMID:23828359", "PMID:24258718", "PMID:8482095", "PMID:8818713", "PMID:8869828", "PMID:9611769", "PMID:9730350", "PPDB:119", "Reaxys:1900390", "UM-BBD_compID:c0131", "Wikipedia:Carbon_dioxide" ; oboInOwl:hasExactSynonym "CARBON DIOXIDE", "Carbon dioxide", "carbon dioxide", "dioxidocarbon", "methanedione" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CO2", "E 290", "E-290", "E290", "R-744", "[CO2]", "carbonic anhydride" ; oboInOwl:id "CHEBI:16526" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbon dioxide" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_23014, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38867 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48706 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76413 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77974 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78017 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_16541 obo:IAO_0000115 "A naturally occurring polypeptide synthesized at the ribosome." ; oboInOwl:hasAlternativeId "CHEBI:8526" ; oboInOwl:hasDbXref "KEGG:C00017" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Protein", "a protein", "polypeptide chain", "protein polypeptide chains" ; oboInOwl:id "CHEBI:16541" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "protein polypeptide chain" ; rdfs:subClassOf obo:CHEBI_15841, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33700 ] . obo:CHEBI_16555 obo:IAO_0000115 "A thioacetic acid that is acetic acid in which the oxygen atom of the hydroxy group has been replaced by a sulfur atom." ; chebi:charge "0" ; chebi:formula "C2H4OS" ; chebi:inchi "InChI=1S/C2H4OS/c1-2(3)4/h1H3,(H,3,4)" ; chebi:inchikey "DUYAAUVXQSMXQP-UHFFFAOYSA-N" ; chebi:mass "76.11856" ; chebi:monoisotopicmass "75.99829" ; chebi:smiles "CC(S)=O" ; oboInOwl:hasAlternativeId "CHEBI:9547" ; oboInOwl:hasDbXref "Beilstein:773684", "CAS:507-09-5", "Gmelin:49262", "KEGG:C01857", "PMID:23298036", "Reaxys:773684" ; oboInOwl:hasExactSynonym "ethanethioic S-acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3COSH", "Thioacetic acid", "acetyl mercaptan", "thioacetic S-acid" ; oboInOwl:id "CHEBI:16555" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ethanethioic S-acid" ; rdfs:subClassOf obo:CHEBI_26952, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_46800 ] . obo:CHEBI_16583 obo:IAO_0000115 "An alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation." ; chebi:charge "0" ; chebi:formula "C4H6O2" ; chebi:inchi "InChI=1S/C4H6O2/c1-3(5)4(2)6/h1-2H3" ; chebi:inchikey "QSJXEFYPDANLFS-UHFFFAOYSA-N" ; chebi:mass "86.08924" ; chebi:monoisotopicmass "86.03678" ; chebi:smiles "CC(=O)C(C)=O" ; oboInOwl:hasAlternativeId "CHEBI:14134", "CHEBI:4479" ; oboInOwl:hasDbXref "Beilstein:605398", "CAS:431-03-8", "HMDB:HMDB0003407", "KEGG:C00741", "PMID:15654607", "PMID:24614328", "Reaxys:605398" ; oboInOwl:hasExactSynonym "butane-2,3-dione" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,3-Butadione", "2,3-Butanedione", "2,3-Diketobutane", "2,3-Dioxobutane", "2,3-butandione", "Biacetyl", "Diacetyl", "Dimethyl glyoxal", "Dimethylglyoxal", "diacetyl" ; oboInOwl:id "CHEBI:16583" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "butane-2,3-dione" ; rdfs:subClassOf obo:CHEBI_51869, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_16646 obo:IAO_0000115 "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." ; oboInOwl:hasAlternativeId "CHEBI:15131", "CHEBI:23008", "CHEBI:9318" ; oboInOwl:hasDbXref "Wikipedia:Carbohydrate" ; oboInOwl:hasExactSynonym "carbohydrate", "carbohydrates" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kohlenhydrat", "Kohlenhydrate", "a carbohydrate", "carbohidrato", "carbohidratos", "glucide", "glucides", "glucido", "glucidos", "hydrates de carbone", "saccharide", "saccharides", "saccharidum" ; oboInOwl:id "CHEBI:16646" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbohydrate" ; rdfs:subClassOf obo:CHEBI_78616 . obo:CHEBI_16670 obo:IAO_0000115 "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid.", "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ; chebi:charge "0" ; chebi:formula "(C2H2NOR)nC2H3NOR" ; oboInOwl:hasAlternativeId "CHEBI:14753", "CHEBI:25906", "CHEBI:7990" ; oboInOwl:hasDbXref "KEGG:C00012" ; oboInOwl:hasExactSynonym "Peptide", "peptides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C2H4NO2R(C2H2NOR)n", "Peptid", "peptido", "peptidos" ; oboInOwl:id "CHEBI:16670" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "peptide" ; rdfs:subClassOf obo:CHEBI_37622, obo:CHEBI_50047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33708 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_60466 ] . obo:CHEBI_166902 chebi:charge "+1" ; chebi:formula "C8H12NO3" ; chebi:inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1" ; chebi:inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-O" ; chebi:mass "170.187" ; chebi:monoisotopicmass "170.08117" ; chebi:smiles "C1=CC(=CC(=C1O)O)C(C[NH3+])O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "noradrenaline" ; oboInOwl:id "CHEBI:166902" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "noradrenaline(1+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33569 ] . obo:CHEBI_16701 obo:IAO_0000115 "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-5 of the ribose ring is mono-, di-, tri- or tetra-phosphorylated." ; chebi:charge "0" ; chebi:formula "C5H9O6PR2" ; chebi:mass "196.09510" ; chebi:monoisotopicmass "196.01367" ; chebi:smiles "O[C@H]1[C@@H]([*])[C@H]([*])O[C@@H]1COP(O)(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:14674", "CHEBI:25603", "CHEBI:7650" ; oboInOwl:hasDbXref "KEGG:C01117" ; oboInOwl:hasExactSynonym "Nucleoside 5'-phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleoside 5'-phosphates" ; oboInOwl:id "CHEBI:16701" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-phosphate" ; rdfs:subClassOf obo:CHEBI_29075, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_57867 ] . obo:CHEBI_16708 obo:IAO_0000115 "The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6." ; chebi:charge "0" ; chebi:formula "C5H5N5" ; chebi:inchi "InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)" ; chebi:inchikey "GFFGJBXGBJISGV-UHFFFAOYSA-N" ; chebi:mass "135.12690" ; chebi:monoisotopicmass "135.05450" ; chebi:smiles "Nc1ncnc2[nH]cnc12" ; oboInOwl:hasAlternativeId "CHEBI:13733", "CHEBI:22236", "CHEBI:2470", "CHEBI:40579" ; oboInOwl:hasDbXref "Beilstein:608603", "CAS:73-24-5", "DrugBank:DB00173", "Drug_Central:89", "Gmelin:3903", "HMDB:HMDB0000034", "KEGG:C00147", "KEGG:D00034", "KNApSAcK:C00001490", "MetaCyc:ADENINE", "PDBeChem:ADE", "PMID:11985597", "PMID:12829005", "PMID:12951489", "PMID:15063338", "PMID:15715490", "PMID:17439666", "PMID:8070089", "Reaxys:608603", "Wikipedia:Adenine" ; oboInOwl:hasExactSynonym "9H-purin-6-amine", "ADENINE", "Adenine", "adenine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "6-Aminopurine", "A", "Ade", "Adenin" ; oboInOwl:id "CHEBI:16708" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adenine" ; rdfs:subClassOf obo:CHEBI_20706, obo:CHEBI_26386, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_16733 chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.05870" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "N[C@H]([*])C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:12909", "CHEBI:13625", "CHEBI:20906", "CHEBI:4097" ; oboInOwl:hasDbXref "KEGG:C00405" ; oboInOwl:hasExactSynonym "D-alpha-amino acid", "D-alpha-amino acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "D-Amino acid", "D-alpha-amino acids" ; oboInOwl:id "CHEBI:16733" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-alpha-amino acid" ; rdfs:subClassOf obo:CHEBI_83925, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_60895 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_59871 ] . obo:CHEBI_167559 obo:IAO_0000115 "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glycans" ; oboInOwl:id "CHEBI:167559" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycan" ; rdfs:subClassOf obo:CHEBI_78616 . obo:CHEBI_16765 obo:IAO_0000115 "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." ; chebi:charge "0" ; chebi:formula "C10H12N2" ; chebi:inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2" ; chebi:inchikey "APJYDQYYACXCRM-UHFFFAOYSA-N" ; chebi:mass "160.21570" ; chebi:monoisotopicmass "160.10005" ; chebi:smiles "NCCc1c[nH]c2ccccc12" ; oboInOwl:hasAlternativeId "CHEBI:15274", "CHEBI:27161", "CHEBI:46157", "CHEBI:9767" ; oboInOwl:hasDbXref "Beilstein:125513", "CAS:61-54-1", "DrugBank:DB08653", "Gmelin:603448", "HMDB:HMDB0000303", "KEGG:C00398", "KNApSAcK:C00001434", "MetaCyc:TRYPTAMINE", "PDBeChem:TSS", "PMID:16126914", "PMID:22770225", "PMID:24345948", "PMID:24558969", "Reaxys:125513", "Wikipedia:Tryptamine" ; oboInOwl:hasExactSynonym "2-(1H-indol-3-yl)ethanamine", "Tryptamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1H-indole-3-ethanamine", "2-(1H-INDOL-3-YL)ETHANAMINE", "2-(3-indolyl)ethylamine", "3-(2-Aminoethyl)indole" ; oboInOwl:id "CHEBI:16765" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tryptamine" ; rdfs:subClassOf obo:CHEBI_27162, obo:CHEBI_38631, obo:CHEBI_38958, obo:CHEBI_64365, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_57887 ] . obo:CHEBI_16856 obo:IAO_0000115 "A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine." ; chebi:charge "0" ; chebi:formula "C10H17N3O6S" ; chebi:inchi "InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1" ; chebi:inchikey "RWSXRVCMGQZWBV-WDSKDSINSA-N" ; chebi:mass "307.320" ; chebi:monoisotopicmass "307.08381" ; chebi:smiles "N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O" ; oboInOwl:hasAlternativeId "CHEBI:12402", "CHEBI:14327", "CHEBI:24334", "CHEBI:42873", "CHEBI:43049", "CHEBI:5437" ; oboInOwl:hasDbXref "CAS:70-18-8", "Chemspider:111188", "DrugBank:DB00143", "Drug_Central:1312", "FooDB:FDB001498", "HMDB:HMDB0000125", "KEGG:C00051", "KEGG:D00014", "KNApSAcK:C00001518", "MetaCyc:GLUTATHIONE", "PDBeChem:GSH", "PMID:10577998", "PMID:1362956", "PMID:14988435", "PMID:16112416", "PMID:16316931", "PMID:16391576", "PMID:16404476", "PMID:16621738", "PMID:16650398", "PMID:16780237", "PMID:16877380", "PMID:17439666", "PMID:19580823", "PMID:4200890", "PMID:4745654", "PMID:8207209", "Reaxys:1729812", "Wikipedia:Glutathione" ; oboInOwl:hasExactSynonym "Glutathione", "L-gamma-glutamyl-L-cysteinylglycine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-L-Glutamyl-L-cysteinylglycine", "GSH", "Glutathione-SH", "N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine", "Reduced glutathione", "gamma-L-Glutamyl-L-cysteinyl-glycine" ; oboInOwl:id "CHEBI:16856" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glutathione" ; rdfs:subClassOf obo:CHEBI_29256, obo:CHEBI_47923, obo:CHEBI_83824, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22586 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_85046 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_57925 ] . obo:CHEBI_16865 obo:IAO_0000115 "A gamma-amino acid that is butanoic acid with the amino substituent located at C-4." ; chebi:charge "0" ; chebi:formula "C4H9NO2" ; chebi:inchi "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" ; chebi:inchikey "BTCSSZJGUNDROE-UHFFFAOYSA-N" ; chebi:mass "103.11980" ; chebi:monoisotopicmass "103.06333" ; chebi:smiles "NCCCC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:1786", "CHEBI:193777", "CHEBI:20318", "CHEBI:40483" ; oboInOwl:hasDbXref "BPDB:2298", "Beilstein:906818", "CAS:56-12-2", "DrugBank:DB02530", "Drug_Central:1262", "Gmelin:49775", "HMDB:HMDB0000112", "KEGG:C00334", "KEGG:D00058", "KNApSAcK:C00001337", "LIPID_MAPS_instance:LMFA01100039", "MetaCyc:4-AMINO-BUTYRATE", "PDBeChem:ABU", "PMID:10630630", "PMID:10930630", "PMID:16276116", "PMID:21614609", "PMID:22770225", "Reaxys:906818", "Wikipedia:Gamma-Aminobutyric_acid" ; oboInOwl:hasExactSynonym "4-aminobutanoic acid", "gamma-Aminobutyric acid", "gamma-aminobutyric acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-Aminobutanoic acid", "4-Aminobutyric acid", "4-aminobutanoic acid", "4-aminobutyric acid", "4Abu", "GABA", "GAMMA-AMINO-BUTANOIC ACID", "gamma-Aminobuttersaeure", "gamma-amino-n-butyric acid", "gamma-aminobutanoic acid", "omega-aminobutyric acid", "piperidic acid", "piperidinic acid" ; oboInOwl:id "CHEBI:16865" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "gamma-aminobutyric acid" ; rdfs:subClassOf obo:CHEBI_25384, obo:CHEBI_33707, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25512 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_62488 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_30772 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30566 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_59888 ] . obo:CHEBI_16988 obo:IAO_0000115 "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in D-glyceraldehyde." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:mass "150.12990" ; chebi:monoisotopicmass "150.05282" ; oboInOwl:hasAlternativeId "CHEBI:13011", "CHEBI:21078" ; oboInOwl:hasDbXref "DrugBank:DB01936", "PMID:24404872", "PMID:24752650" ; oboInOwl:hasExactSynonym "D-ribo-pentose", "D-ribose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "D-Rib" ; oboInOwl:id "CHEBI:16988" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-ribose" ; rdfs:subClassOf obo:CHEBI_33942, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_46997 ] . obo:CHEBI_16990 obo:IAO_0000115 "A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin." ; chebi:charge "0" ; chebi:formula "C33H36N4O6" ; chebi:inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-" ; chebi:inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-N" ; chebi:mass "584.673" ; chebi:monoisotopicmass "584.26348" ; chebi:smiles "CC1=C(C=C)\\C(NC1=O)=C\\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\\C=C2/NC(=O)C(C=C)=C2C)N1" ; oboInOwl:hasAlternativeId "CHEBI:13898", "CHEBI:22870", "CHEBI:3099" ; oboInOwl:hasDbXref "Beilstein:74376", "CAS:635-65-4", "Gmelin:411033", "HMDB:HMDB0000054", "KEGG:C00486", "KNApSAcK:C00029828", "MetaCyc:BILIRUBIN", "PDBeChem:BLR", "PMID:12799017", "PMID:18442622", "PMID:23763371", "PMID:23768684", "PMID:30224965", "PMID:8605219", "PMID:9587403", "Reaxys:74376", "Wikipedia:Bilirubin" ; oboInOwl:hasExactSynonym "3,18-diethenyl-2,7,13,17-tetramethyl-1,19-dioxo-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid", "bilirubin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinylbiline-8,12-dipropionic acid", "2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid", "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoic acid", "8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbiladiene-ac-1,19(21H,24H)-dione", "Bilirubin", "bilirubin(Z,Z)", "bilirubin-IXalpha" ; oboInOwl:id "CHEBI:16990" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bilirubin IXalpha" ; rdfs:subClassOf obo:CHEBI_35692, obo:CHEBI_36735, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_142163 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22586 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_57977 ] . obo:CHEBI_16991 obo:IAO_0000115 "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms." ; oboInOwl:hasAlternativeId "CHEBI:13302", "CHEBI:21123", "CHEBI:33698", "CHEBI:4291" ; oboInOwl:hasDbXref "CAS:9007-49-2", "KEGG:C00039" ; oboInOwl:hasExactSynonym "Deoxyribonucleic acid", "deoxyribonucleic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(Deoxyribonucleotide)m", "(Deoxyribonucleotide)n", "(Deoxyribonucleotide)n+m", "DNA", "DNAn", "DNAn+1", "DNS", "Desoxyribonukleinsaeure", "deoxyribonucleic acids", "desoxyribose nucleic acid", "thymus nucleic acid" ; oboInOwl:id "CHEBI:16991" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "deoxyribonucleic acid" ; rdfs:subClassOf obo:CHEBI_33696, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33793 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50298 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ] . obo:CHEBI_17051 chebi:charge "-1" ; chebi:formula "F" ; chebi:inchi "InChI=1S/FH/h1H/p-1" ; chebi:inchikey "KRHYYFGTRYWZRS-UHFFFAOYSA-M" ; chebi:mass "18.99840" ; chebi:monoisotopicmass "18.99895" ; chebi:smiles "[F-]" ; oboInOwl:hasAlternativeId "CHEBI:14271", "CHEBI:49593", "CHEBI:5113" ; oboInOwl:hasDbXref "CAS:16984-48-8", "Gmelin:14905", "KEGG:C00742", "PDBeChem:F" ; oboInOwl:hasExactSynonym "Fluoride", "fluoride", "fluoride(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "F(-)", "F-", "FLUORIDE ION", "Fluoride ion", "Fluorine anion" ; oboInOwl:id "CHEBI:17051" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluoride" ; rdfs:subClassOf obo:CHEBI_16042, obo:CHEBI_36895, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29228 ] . obo:CHEBI_17062 chebi:charge "0" ; chebi:formula "CH4NR" ; chebi:mass "30.04920" ; chebi:monoisotopicmass "30.03437" ; chebi:smiles "NC[*]" ; oboInOwl:hasAlternativeId "CHEBI:13431", "CHEBI:8749" ; oboInOwl:hasDbXref "KEGG:C00375" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RCH2NH2", "primary aliphatic amines" ; oboInOwl:id "CHEBI:17062" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "primary aliphatic amine" ; rdfs:subClassOf obo:CHEBI_32877, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_58001 ] . obo:CHEBI_17087 obo:IAO_0000115 "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." ; chebi:charge "0" ; chebi:formula "COR2" ; chebi:mass "28.010" ; chebi:monoisotopicmass "27.99491" ; chebi:smiles "[*]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13427", "CHEBI:13646", "CHEBI:24974", "CHEBI:6127", "CHEBI:8742" ; oboInOwl:hasDbXref "KEGG:C01450", "Wikipedia:Ketone" ; oboInOwl:hasExactSynonym "Ketone", "ketones" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Keton", "R-CO-R'", "a ketone", "cetone", "ketones" ; oboInOwl:id "CHEBI:17087" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ketone" ; rdfs:subClassOf obo:CHEBI_36586 . obo:CHEBI_17089 obo:IAO_0000115 "A compound in which a carbohydrate component is covalently bound to a protein component." ; oboInOwl:hasAlternativeId "CHEBI:14349", "CHEBI:5481", "CHEBI:5493" ; oboInOwl:hasDbXref "KEGG:C00326" ; oboInOwl:hasExactSynonym "Glycoprotein", "glycoproteins" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Glykoprotein", "Glykoproteine", "a glycoprotein", "glicoproteina", "glicoproteinas", "glycoproteine", "glycoproteines" ; oboInOwl:id "CHEBI:17089" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycoprotein" ; rdfs:subClassOf obo:CHEBI_33837, obo:CHEBI_63299 . obo:CHEBI_17120 obo:IAO_0000115 "A short-chain fatty acid anion that is the conjugate base of hexanoic acid (also known as caproic acid)." ; chebi:charge "-1" ; chebi:formula "C6H11O2" ; chebi:inchi "InChI=1S/C6H12O2/c1-2-3-4-5-6(7)8/h2-5H2,1H3,(H,7,8)/p-1" ; chebi:inchikey "FUZZWVXGSFPDMH-UHFFFAOYSA-M" ; chebi:mass "115.15034" ; chebi:monoisotopicmass "115.07645" ; chebi:smiles "CCCCCC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:14398", "CHEBI:24569" ; oboInOwl:hasDbXref "Beilstein:3601453", "CAS:151-33-7", "ECMDB:ECMDB21229", "Gmelin:326340", "KEGG:C01585", "MetaCyc:HEXANOATE" ; oboInOwl:hasExactSynonym "hexanoate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-hexanoate", "1-pentacarboxylate", "1-pentanecarboxylate", "CH3-[CH2]4-COO(-)", "butylacetate", "caproate", "capronate", "hexoate", "hexylate", "n-caproate", "n-hexanoate", "n-hexoate", "n-hexylate", "nPnCO2 anion", "pentanecarboxylate", "pentylformate" ; oboInOwl:id "CHEBI:17120" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hexanoate" ; rdfs:subClassOf obo:CHEBI_58951, obo:CHEBI_58954, obo:CHEBI_78116, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_30776 ] . obo:CHEBI_17134 obo:IAO_0000115 "A member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates." ; chebi:charge "0" ; chebi:formula "C8H11NO2" ; chebi:inchi "InChI=1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2" ; chebi:inchikey "QHGUCRYDKWKLMG-UHFFFAOYSA-N" ; chebi:mass "153.17848" ; chebi:monoisotopicmass "153.07898" ; chebi:smiles "NCC(O)c1ccc(O)cc1" ; oboInOwl:hasAlternativeId "CHEBI:11191", "CHEBI:25655", "CHEBI:571" ; oboInOwl:hasDbXref "Beilstein:1211019", "CAS:104-14-3", "Drug_Central:3396", "KEGG:C04227", "LINCS:LSM-4975" ; oboInOwl:hasExactSynonym "4-(2-amino-1-hydroxyethyl)phenol", "Octopamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-(4-Hydroxyphenyl)-2-aminoethanol", "1-(p-hydroxyphenyl)-2-aminoethanol", "Octopamin", "alpha-(aminomethyl)-4-hydroxybenzenemethanol", "alpha-(aminomethyl)-p-hydroxybenzyl alcohol", "beta-hydroxytyramine", "norsynephrine", "octopaminum", "p-Hydroxyphenylethanolamine" ; oboInOwl:id "CHEBI:17134" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "octopamine" ; rdfs:subClassOf obo:CHEBI_25990, obo:CHEBI_27175, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25512 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_58025 ] . obo:CHEBI_17137 chebi:charge "-1" ; chebi:formula "HO3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1" ; chebi:inchikey "LSNNMFCWUKXFEE-UHFFFAOYSA-M" ; chebi:mass "81.07214" ; chebi:monoisotopicmass "80.96519" ; chebi:smiles "OS([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:13367", "CHEBI:5598" ; oboInOwl:hasDbXref "CAS:15181-46-1", "Gmelin:1455", "KEGG:C11481", "PDBeChem:SO3" ; oboInOwl:hasExactSynonym "hydrogen(trioxidosulfate)(1-)", "hydrogensulfite(1-)", "hydrogentrioxosulfate(1-)", "hydrogentrioxosulfate(IV)", "hydroxidodioxidosulfate(1-)", "monohydrogentrioxosulfate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bisulfite", "HSO3(-)", "HSO3-", "Hydrogen sulfite", "[SO2(OH)](-)", "bisulfite", "bisulphite", "hydrogen sulfite(1-)", "hydrosulfite anion" ; oboInOwl:id "CHEBI:17137" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogensulfite" ; rdfs:subClassOf obo:CHEBI_33482, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17359 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_48854 ] . obo:CHEBI_171664 obo:IAO_0000115 "An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amebicide", "amebicides", "amoebicide", "amoebicides", "anti-amoebic agent", "anti-amoebic agents", "anti-amoebic drug", "anti-amoebic drugs", "antiamoebic", "antiamoebic agents", "antiamoebic drug", "antiamoebic drugs", "antiamoebics" ; oboInOwl:id "CHEBI:171664" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antiamoebic agent" ; rdfs:subClassOf obo:CHEBI_35442 . obo:CHEBI_17234 obo:IAO_0000115 "An aldohexose used as a source of energy and metabolic intermediate." ; chebi:charge "0" ; chebi:formula "C6H12O6" ; chebi:mass "180.15588" ; chebi:monoisotopicmass "180.06339" ; oboInOwl:hasAlternativeId "CHEBI:14313", "CHEBI:24277", "CHEBI:33929", "CHEBI:5418" ; oboInOwl:hasDbXref "CAS:50-99-7", "KEGG:C00293", "Wikipedia:Glucose" ; oboInOwl:hasExactSynonym "Glucose", "gluco-hexose", "glucose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "DL-glucose", "Glc", "Glukose" ; oboInOwl:id "CHEBI:17234" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glucose" ; rdfs:subClassOf obo:CHEBI_33917, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ] . obo:CHEBI_17258 obo:IAO_0000115 "The 7H-tautomer of purine." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" ; chebi:inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" ; chebi:mass "120.11222" ; chebi:monoisotopicmass "120.04360" ; chebi:smiles "c1ncc2[nH]cnc2n1" ; oboInOwl:hasAlternativeId "CHEBI:14968", "CHEBI:8639" ; oboInOwl:hasDbXref "Beilstein:3200", "Gmelin:601779", "HMDB:HMDB0001366", "KEGG:C15587", "Reaxys:3200" ; oboInOwl:hasExactSynonym "7H-purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Purine", "Purine base" ; oboInOwl:id "CHEBI:17258" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "7H-purine" ; rdfs:subClassOf obo:CHEBI_35584, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35586 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35588 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_173084 obo:IAO_0000115 "Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms." ; oboInOwl:hasDbXref "PMID:32015325", "PMID:32256352", "PMID:32413317", "PMID:33495651", "Wikipedia:Ferroptosis" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ferroptosis inhibitors" ; oboInOwl:id "CHEBI:173084" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ferroptosis inhibitor" ; rdfs:subClassOf obo:CHEBI_35222, obo:CHEBI_52206 . obo:CHEBI_17326 chebi:charge "0" ; chebi:formula "C5H12O13P3R" ; chebi:mass "373.063" ; chebi:monoisotopicmass "372.94908" ; chebi:smiles "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)(O)O)(=O)O)(=O)O" ; oboInOwl:hasAlternativeId "CHEBI:13411", "CHEBI:14677", "CHEBI:25610", "CHEBI:7442", "CHEBI:7655" ; oboInOwl:hasDbXref "KEGG:C00201" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NTP", "Nucleoside triphosphate", "nucleoside triphosphates" ; oboInOwl:id "CHEBI:17326" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-triphoshate" ; rdfs:subClassOf obo:CHEBI_25608, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58104 ] . obo:CHEBI_17359 obo:IAO_0000115 "A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3)." ; chebi:charge "-2" ; chebi:formula "O3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2" ; chebi:inchikey "LSNNMFCWUKXFEE-UHFFFAOYSA-L" ; chebi:mass "80.06420" ; chebi:monoisotopicmass "79.95791" ; chebi:smiles "[O-]S([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:15139", "CHEBI:45548" ; oboInOwl:hasDbXref "CAS:14265-45-3", "Gmelin:1449", "PDBeChem:SO3" ; oboInOwl:hasExactSynonym "sulfite", "trioxidosulfate(2-)", "trioxosulfate(2-)", "trioxosulfate(IV)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SO3", "SO3(2-)", "SULFITE ION", "[SO3](2-)", "sulphite" ; oboInOwl:id "CHEBI:17359" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfite" ; rdfs:subClassOf obo:CHEBI_33482, obo:CHEBI_48154, obo:CHEBI_79388, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17137 ] . obo:CHEBI_17478 obo:IAO_0000115 "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group." ; chebi:charge "0" ; chebi:formula "CHOR" ; chebi:mass "29.01800" ; chebi:monoisotopicmass "29.00274" ; chebi:smiles "[H]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13432", "CHEBI:13753", "CHEBI:13805", "CHEBI:13806", "CHEBI:22291", "CHEBI:2554", "CHEBI:8750" ; oboInOwl:hasDbXref "KEGG:C00071" ; oboInOwl:hasExactSynonym "Aldehyde", "aldehyde", "aldehydes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aldehyd", "RC(=O)H", "RCHO", "aldehido", "aldehidos", "aldehydes", "aldehydum", "an aldehyde" ; oboInOwl:id "CHEBI:17478" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aldehyde" ; rdfs:subClassOf obo:CHEBI_36586, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_42485 ] . obo:CHEBI_17489 obo:IAO_0000115 "A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase." ; chebi:charge "0" ; chebi:formula "C10H12N5O6P" ; chebi:inchi "InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "IVOMOUWHDPKRLL-KQYNXXCUSA-N" ; chebi:mass "329.20614" ; chebi:monoisotopicmass "329.05252" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:11673", "CHEBI:1325", "CHEBI:19827", "CHEBI:41588" ; oboInOwl:hasDbXref "Beilstein:52645", "CAS:60-92-4", "DrugBank:DB02527", "HMDB:HMDB0000058", "KEGG:C00575", "KNApSAcK:C00001497", "MetaCyc:CAMP", "PDBeChem:CMP", "PMID:16295522", "PMID:18372334", "PMID:22770225", "Reaxys:52645", "Wikipedia:Cyclic_AMP" ; oboInOwl:hasExactSynonym "3',5'-Cyclic AMP", "adenosine 3',5'-(hydrogen phosphate)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE", "Adenosine 3',5'-cyclic phosphate", "Adenosine 3',5'-phosphate", "Cyclic AMP", "Cyclic adenylic acid", "adenosine 3',5'-cyclic monophosphate", "cAMP" ; oboInOwl:id "CHEBI:17489" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "3',5'-cyclic AMP" ; rdfs:subClassOf obo:CHEBI_19834, obo:CHEBI_61296, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58165 ] . obo:CHEBI_17522 obo:IAO_0000115 "A carbohydrate that is an acyclic polyol having the general formula HOCH2[CH(OH)]nCH2OH (formally derivable from an aldose by reduction of the carbonyl group)." ; chebi:charge "0" ; chebi:formula "(CH2O)nC2H6O2" ; oboInOwl:hasAlternativeId "CHEBI:13754", "CHEBI:22298", "CHEBI:2556" ; oboInOwl:hasDbXref "KEGG:C00717", "Wikipedia:Glycerin" ; oboInOwl:hasExactSynonym "Alditol", "alditol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Glycitol", "Sugar alcohol", "alditols" ; oboInOwl:id "CHEBI:17522" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alditol" ; rdfs:subClassOf obo:CHEBI_16646, obo:CHEBI_26191 . obo:CHEBI_17544 obo:IAO_0000115 "The carbon oxoanion resulting from the removal of a proton from carbonic acid." ; chebi:charge "-1" ; chebi:formula "CHO3" ; chebi:inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1" ; chebi:inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-M" ; chebi:mass "61.01684" ; chebi:monoisotopicmass "60.99312" ; chebi:smiles "OC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:13363", "CHEBI:22863", "CHEBI:40961", "CHEBI:5589" ; oboInOwl:hasDbXref "Beilstein:3903504", "CAS:71-52-3", "Gmelin:49249", "HMDB:HMDB0000595", "KEGG:C00288", "MetaCyc:HCO3", "PDBeChem:BCT", "PMID:17215880", "PMID:17505962", "PMID:18439416", "PMID:28732801", "PMID:29150416", "PMID:29460248", "PMID:29466234", "PMID:4208463", "Wikipedia:Bicarbonate" ; oboInOwl:hasExactSynonym "Hydrogencarbonate", "hydrogen(trioxidocarbonate)(1-)", "hydrogencarbonate", "hydrogencarbonate(1-)", "hydrogentrioxocarbonate(1-)", "hydrogentrioxocarbonate(IV)", "hydroxidodioxidocarbonate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Acid carbonate", "BICARBONATE ION", "Bicarbonate", "HCO3(-)", "HCO3-", "[CO2(OH)](-)", "hydrogen carbonate" ; oboInOwl:id "CHEBI:17544" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogencarbonate" ; rdfs:subClassOf obo:CHEBI_35604, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_41609 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_28976 ] . obo:CHEBI_17561 obo:IAO_0000115 "An optically active form of cysteine having L-configuration." ; chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-N" ; chebi:mass "121.15800" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "N[C@@H](CS)C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:13095", "CHEBI:21261", "CHEBI:41227", "CHEBI:41700", "CHEBI:41768", "CHEBI:41781", "CHEBI:41811", "CHEBI:6207" ; oboInOwl:hasDbXref "Beilstein:1721408", "CAS:52-90-4", "DrugBank:DB00151", "Drug_Central:769", "ECMDB:ECMDB00574", "Gmelin:49991", "HMDB:HMDB0000574", "KEGG:C00097", "KEGG:D00026", "KNApSAcK:C00001351", "MetaCyc:CYS", "PDBeChem:CYS", "PMID:11732994", "PMID:13761469", "PMID:22735334", "Reaxys:1721408", "Wikipedia:Cysteine", "YMDB:YMDB00046" ; oboInOwl:hasExactSynonym "L-Cysteine", "L-cysteine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R)-2-amino-3-mercaptopropanoic acid", "(2R)-2-amino-3-sulfanylpropanoic acid", "(R)-2-amino-3-mercaptopropanoic acid", "C", "CYSTEINE", "Cys", "E 920", "E-920", "E920", "FREE CYSTEINE", "L-2-Amino-3-mercaptopropionic acid", "L-Cystein", "L-Zystein" ; oboInOwl:id "CHEBI:17561" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-cysteine" ; rdfs:subClassOf obo:CHEBI_15356, obo:CHEBI_26650, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64577 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32442 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32445 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_16375 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35235 ] . obo:CHEBI_17568 obo:IAO_0000115 "A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription." ; chebi:charge "0" ; chebi:formula "C4H4N2O2" ; chebi:inchi "InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)" ; chebi:inchikey "ISAKRJDGNUQOIC-UHFFFAOYSA-N" ; chebi:mass "112.08684" ; chebi:monoisotopicmass "112.02728" ; chebi:smiles "O=c1cc[nH]c(=O)[nH]1" ; oboInOwl:hasAlternativeId "CHEBI:15288", "CHEBI:27210", "CHEBI:46375", "CHEBI:9882" ; oboInOwl:hasDbXref "Beilstein:606623", "CAS:66-22-8", "DrugBank:DB03419", "Gmelin:2896", "HMDB:HMDB0000300", "KEGG:C00106", "KEGG:D00027", "KNApSAcK:C00001513", "MetaCyc:URACIL", "PDBeChem:URA", "PMID:11279060", "PMID:12855717", "PMID:15274295", "PMID:16834123", "PMID:17439666", "PMID:18533995", "PMID:18815805", "PMID:19175333", "PMID:22020693", "PMID:22074393", "PMID:22120518", "PMID:22171528", "PMID:22237209", "PMID:22299724", "PMID:22356544", "PMID:22447672", "PMID:22483865", "PMID:22567906", "PMID:22685418", "PMID:3654008", "Reaxys:606623", "Wikipedia:Uracil" ; oboInOwl:hasExactSynonym "URACIL", "Uracil", "pyrimidine-2,4(1H,3H)-dione", "uracil" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,4(1H,3H)-pyrimidinedione", "2,4-Dioxopyrimidine", "2,4-Pyrimidinedione", "U", "Ura", "Urazil" ; oboInOwl:id "CHEBI:17568" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "uracil" ; rdfs:subClassOf obo:CHEBI_26432, obo:CHEBI_38337, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50266 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50904 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_43254 ] . obo:CHEBI_17590 obo:IAO_0000115 "A straight chain alkane composed of 8 carbon atoms." ; chebi:charge "0" ; chebi:formula "C8H18" ; chebi:inchi "InChI=1S/C8H18/c1-3-5-7-8-6-4-2/h3-8H2,1-2H3" ; chebi:inchikey "TVMXDCGIABBOFY-UHFFFAOYSA-N" ; chebi:mass "114.22852" ; chebi:monoisotopicmass "114.14085" ; chebi:smiles "CCCCCCCC" ; oboInOwl:hasAlternativeId "CHEBI:14680", "CHEBI:25465", "CHEBI:25645", "CHEBI:44621", "CHEBI:7723" ; oboInOwl:hasDbXref "Beilstein:1696875", "CAS:111-65-9", "DrugBank:DB02440", "Gmelin:82412", "HMDB:HMDB0001485", "KEGG:C01387", "LIPID_MAPS_instance:LMFA11000002", "MetaCyc:CPD-148", "PDBeChem:OCT", "PMID:11255151", "PMID:24354334", "Reaxys:1696875", "UM-BBD_compID:c0044", "Wikipedia:Octane" ; oboInOwl:hasExactSynonym "Octane", "octane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3-[CH2]6-CH3", "N-OCTANE", "Oktan", "n-Octane", "n-Oktan" ; oboInOwl:id "CHEBI:17590" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "octane" ; rdfs:subClassOf obo:CHEBI_18310, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ] . obo:CHEBI_176497 obo:IAO_0000115 "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan." ; oboInOwl:hasDbXref "PMID:23372317", "PMID:28580190", "PMID:30885572", "PMID:33144142", "PMID:33973253", "PMID:34606237", "Wikipedia:Geroprotector" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-aging agent", "anti-aging agents", "anti-aging drug", "anti-aging drugs", "geroprotective agent", "geroprotective agents", "geroprotectors" ; oboInOwl:id "CHEBI:176497" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "geroprotector" ; rdfs:subClassOf obo:CHEBI_50267 . obo:CHEBI_17688 obo:IAO_0000115 "A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum." ; chebi:charge "0" ; chebi:formula "C10H14N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1" ; chebi:inchikey "SNICXCGAKADSCV-JTQLQIEISA-N" ; chebi:mass "162.236" ; chebi:monoisotopicmass "162.11570" ; chebi:smiles "[H][C@]1(CCCN1C)C1=CC=CN=C1" ; oboInOwl:hasAlternativeId "CHEBI:14653", "CHEBI:25536", "CHEBI:44268", "CHEBI:7562" ; oboInOwl:hasDbXref "BPDB:485", "Beilstein:3604351", "Beilstein:82109", "CAS:54-11-5", "DrugBank:DB00184", "Drug_Central:1920", "HMDB:HMDB0001934", "KEGG:C00745", "KEGG:D03365", "KNApSAcK:C00002057", "LINCS:LSM-2093", "MetaCyc:NICOTINE", "PDBeChem:NCT", "PMID:11209966", "PMID:11322615", "PMID:11406005", "PMID:11719700", "PMID:11768184", "PMID:11821649", "PMID:11851194", "PMID:12575980", "PMID:12692774", "PMID:12769614", "PMID:12850578", "PMID:12971663", "PMID:13590907", "PMID:14674846", "PMID:14761239", "PMID:14975706", "PMID:15019421", "PMID:15027713", "PMID:15251917", "PMID:15276225", "PMID:15380834", "PMID:15502843", "PMID:15527885", "PMID:15707677", "PMID:15734728", "PMID:15826609", "PMID:15894687", "PMID:15902919", "PMID:15960296", "PMID:15963341", "PMID:16059663", "PMID:16212709", "PMID:16333621", "PMID:16370520", "PMID:16496293", "PMID:17023324", "PMID:17206646", "PMID:17292347", "PMID:17350101", "PMID:17498763", "PMID:17504235", "PMID:17525204", "PMID:17560039", "PMID:17683794", "PMID:18380035", "PMID:18383130", "PMID:18490768", "PMID:18683238", "PMID:18685152", "PMID:18805442", "PMID:18922921", "PMID:19100291", "PMID:19100331", "PMID:19287496", "PMID:19389046", "PMID:19448649", "PMID:19465085", "PMID:19850423", "PMID:19954906", "PMID:21521420", "PMID:21636612", "PMID:21822688", "PMID:21945235", "PMID:21947355", "PMID:22030716", "PMID:22129149", "PMID:22218403", "PMID:22265518", "PMID:22331007", "PMID:22377934", "PMID:22459798", "PMID:22529223", "PMID:22530136", "PMID:27951416", "PMID:28187919", "PMID:28391535", "PMID:28574230", "PMID:28641297", "PMID:28678400", "PMID:28683421", "PMID:28686840", "PMID:28698187", "PMID:28700952", "PMID:28704277", "PMID:28710519", "PMID:28711472", "PMID:28714396", "PMID:28718768", "PMID:28718828", "PMID:28726253", "PMID:28735272", "Reaxys:82109", "Wikipedia:Nicotine" ; oboInOwl:hasExactSynonym "(S)-Nicotine", "(S)-nicotine", "3-[(2S)-1-methylpyrrolidin-2-yl]pyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-3-(1-Methyl-2-pyrrolidyl)pyridine", "(-)-3-(N-Methylpyrrolidino)pyridine", "(-)-nicotine", "(R)-3-(1-Methyl-2-pyrrolidinyl)pyridine", "(S)-(-)-nicotine", "(S)-3-(1-methylpyrrolidin-2-yl)pyridine", "(S)-3-(N-methylpyrrolidin-2-yl)pyridine", "1-Methyl-2-(3-pyridyl)pyrrolidine", "3-(1-Methyl-2-pyrollidinyl)pyridine", "3-(1-Methylpyrrolidin-2-yl)pyridine", "3-(2-(N-methylpyrrolidinyl))pyridine", "3-(N-methylpyrollidino)pyridine", "L(-)-nicotine", "L-3-(1-Methyl-2-pyrrolidyl)pyridine", "L-Nicotine", "Nicotine" ; oboInOwl:id "CHEBI:17688" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(S)-nicotine" ; rdfs:subClassOf obo:CHEBI_138000, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22917 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35474 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_47958 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_49110 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50846 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_52290 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59163 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_59806 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_39162 ] . obo:CHEBI_17754 obo:IAO_0000115 "A triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups." ; chebi:charge "0" ; chebi:formula "C3H8O3" ; chebi:inchi "InChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2" ; chebi:inchikey "PEDCQBHIVMGVHV-UHFFFAOYSA-N" ; chebi:mass "92.09382" ; chebi:monoisotopicmass "92.04734" ; chebi:smiles "OCC(O)CO" ; oboInOwl:hasAlternativeId "CHEBI:131422", "CHEBI:14334", "CHEBI:24351", "CHEBI:42998", "CHEBI:5448" ; oboInOwl:hasDbXref "Beilstein:635685", "CAS:56-81-5", "Chemspider:733", "DrugBank:DB04077", "Drug_Central:1316", "ECMDB:ECMDB00131", "FooDB:FDB000756", "Gmelin:26279", "HMDB:HMDB0000131", "KEGG:C00116", "KEGG:D00028", "KNApSAcK:C00001163", "LINCS:LSM-37180", "MetaCyc:GLYCEROL", "PDB:2AJS", "PDB:2D03", "PDBeChem:GOL", "PMID:11302662", "PMID:11958517", "PMID:11994365", "PMID:12672239", "PMID:12687625", "PMID:12689633", "PMID:12713573", "PMID:14559393", "PMID:14563847", "PMID:15026783", "PMID:15342117", "PMID:15786693", "PMID:15983192", "PMID:16244855", "PMID:16258193", "PMID:16319039", "PMID:16349488", "PMID:16475911", "PMID:16651733", "PMID:16664750", "PMID:16901854", "PMID:17336832", "PMID:17439666", "PMID:17979222", "PMID:19184438", "PMID:19231894", "PMID:19460032", "PMID:19548674", "PMID:19795216", "PMID:19956799", "PMID:22705534", "PMID:23562176", "PMID:23747440", "PMID:24643482", "PMID:24835191", "PMID:25108762", "PMID:558160", "PMID:6299616", "PMID:7031247", "PMID:7392035", "PPDB:1317", "Reaxys:635685", "UM-BBD_compID:c0066", "Wikipedia:Glycerol", "YMDB:YMDB00283" ; oboInOwl:hasExactSynonym "GLYCEROL", "Glycerol", "glycerol", "propane-1,2,3-triol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2,3-Propanetriol", "1,2,3-Trihydroxypropane", "Glycerin", "Glyceritol", "Glyzerin", "Gro", "Oelsuess", "Propanetriol", "Trihydroxypropane", "glycerine", "glycerol", "glycerolum", "glycyl alcohol" ; oboInOwl:id "CHEBI:17754" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycerol" ; rdfs:subClassOf obo:CHEBI_17522, obo:CHEBI_27136, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25728 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27780 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84735 ] . obo:CHEBI_17790 obo:IAO_0000115 "The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group." ; chebi:charge "0" ; chebi:formula "CH4O" ; chebi:inchi "InChI=1S/CH4O/c1-2/h2H,1H3" ; chebi:inchikey "OKKJLVBELUTLKV-UHFFFAOYSA-N" ; chebi:mass "32.04186" ; chebi:monoisotopicmass "32.02621" ; chebi:smiles "CO" ; oboInOwl:hasAlternativeId "CHEBI:14588", "CHEBI:25227", "CHEBI:44080", "CHEBI:44553", "CHEBI:6816" ; oboInOwl:hasDbXref "Beilstein:1098229", "CAS:67-56-1", "Gmelin:449", "HMDB:HMDB0001875", "KEGG:C00132", "KEGG:D02309", "MetaCyc:METOH", "PDBeChem:MOH", "PMID:11141607", "PMID:11430978", "PMID:11489599", "PMID:11680737", "PMID:11684179", "PMID:14012711", "PMID:14678513", "PMID:14760634", "PMID:15172721", "PMID:15906011", "PMID:16705261", "PMID:17451998", "PMID:17733096", "PMID:19064074", "PMID:19850112", "PMID:20314698", "Reaxys:1098229", "UM-BBD_compID:c0132", "Wikipedia:Methanol" ; oboInOwl:hasExactSynonym "METHANOL", "Methanol", "methanol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3OH", "MeOH", "Methyl alcohol", "Methylalkohol", "carbinol", "spirit of wood", "wood alcohol", "wood naphtha", "wood spirit" ; oboInOwl:id "CHEBI:17790" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methanol" ; rdfs:subClassOf obo:CHEBI_134179, obo:CHEBI_15734, obo:CHEBI_50584, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_131604 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33292 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48360 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_52090 ] . obo:CHEBI_17792 obo:IAO_0000115 "A compound containing at least one carbon-halogen bond (where X is a halogen atom)." ; chebi:charge "0" ; chebi:formula "RX" ; chebi:smiles "**" ; oboInOwl:hasAlternativeId "CHEBI:13444", "CHEBI:36684", "CHEBI:8767" ; oboInOwl:hasDbXref "KEGG:C01322", "MetaCyc:Organohalogen-Compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RX", "organic halide", "organic halides", "organohalogen compounds" ; oboInOwl:id "CHEBI:17792" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organohalogen compound" ; rdfs:subClassOf obo:CHEBI_33285, obo:CHEBI_37578 . obo:CHEBI_17883 obo:IAO_0000115 "A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms." ; chebi:charge "0" ; chebi:formula "ClH", "HCl" ; chebi:inchi "InChI=1S/ClH/h1H" ; chebi:inchikey "VEXZGXHMUGYJMC-UHFFFAOYSA-N" ; chebi:mass "36.46064" ; chebi:monoisotopicmass "35.97668" ; chebi:smiles "Cl[H]" ; oboInOwl:hasAlternativeId "CHEBI:13364", "CHEBI:24635", "CHEBI:5590" ; oboInOwl:hasDbXref "CAS:7647-01-0", "Drug_Central:4568", "Gmelin:322", "HMDB:HMDB0002306", "KEGG:C01327", "KEGG:D02057", "MetaCyc:HCL", "PMID:15823700", "PMID:17492841", "PMID:22804993", "Reaxys:1098214", "Wikipedia:HCl", "Wikipedia:Hydrochloric_acid" ; oboInOwl:hasExactSynonym "Hydrogen chloride", "chlorane", "chloridohydrogen", "hydrogen chloride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Chlorwasserstoff", "HCl", "Hydrochloride", "Hydrogenchlorid", "Wasserstoffchlorid", "[HCl]", "chlorure d'hydrogene", "cloruro de hidrogeno", "hydrochloric acid" ; oboInOwl:id "CHEBI:17883" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogen chloride" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_18140, obo:CHEBI_23117, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17996 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_50315 ] . obo:CHEBI_17891 obo:IAO_0000115 "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." ; oboInOwl:hasAlternativeId "CHEBI:14202", "CHEBI:4697" ; oboInOwl:hasDbXref "KEGG:C01351" ; oboInOwl:hasExactSynonym "Donor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Donator", "donneur" ; oboInOwl:id "CHEBI:17891" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "donor" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_17968 obo:IAO_0000115 "A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group." ; chebi:charge "-1" ; chebi:formula "C4H7O2" ; chebi:inchi "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)/p-1" ; chebi:inchikey "FERIUCNNQQJTOY-UHFFFAOYSA-M" ; chebi:mass "87.09718" ; chebi:monoisotopicmass "87.04515" ; chebi:smiles "CCCC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:13924", "CHEBI:22946" ; oboInOwl:hasDbXref "Beilstein:3601060", "CAS:461-55-2", "Gmelin:324289", "KEGG:C00246", "MetaCyc:BUTYRIC_ACID", "PMID:17190852", "PMID:7496326", "Reaxys:3601060", "UM-BBD_compID:c0035" ; oboInOwl:hasExactSynonym "butanoate", "butyrate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-butanoate", "1-butyrate", "1-propanecarboxylate", "CH3-[CH2]2-COO(-)", "butanate", "butanoate", "butanoic acid, ion(1-)", "n-butanoate", "n-butyrate", "propanecarboxylate", "propylformate" ; oboInOwl:id "CHEBI:17968" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "butyrate" ; rdfs:subClassOf obo:CHEBI_78115, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_61115 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_30772 ] . obo:CHEBI_17972 chebi:charge "0" ; chebi:formula "C5H12O13P3R" ; chebi:mass "373.063" ; chebi:monoisotopicmass "372.94908" ; oboInOwl:hasAlternativeId "CHEBI:15047", "CHEBI:26559", "CHEBI:8846" ; oboInOwl:hasDbXref "KEGG:C03802" ; oboInOwl:hasExactSynonym "Ribonucleoside triphosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleoside triphosphates" ; oboInOwl:id "CHEBI:17972" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribonucleoside triphosphate" ; rdfs:subClassOf obo:CHEBI_17326 . obo:CHEBI_17996 obo:IAO_0000115 "A halide anion formed when chlorine picks up an electron to form an an anion." ; chebi:charge "-1" ; chebi:formula "Cl" ; chebi:inchi "InChI=1S/ClH/h1H/p-1" ; chebi:inchikey "VEXZGXHMUGYJMC-UHFFFAOYSA-M" ; chebi:mass "35.45270" ; chebi:monoisotopicmass "34.96940" ; chebi:smiles "[Cl-]" ; oboInOwl:hasAlternativeId "CHEBI:13291", "CHEBI:13970", "CHEBI:3616", "CHEBI:3731", "CHEBI:48804" ; oboInOwl:hasDbXref "Beilstein:3587171", "CAS:16887-00-6", "Gmelin:14910", "KEGG:C00115", "KEGG:C00698", "PDBeChem:CL", "UM-BBD_compID:c0884" ; oboInOwl:hasExactSynonym "Chloride", "chloride", "chloride(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CHLORIDE ION", "Chloride ion", "Chloride(1-)", "Chlorine anion", "Cl(-)", "Cl-" ; oboInOwl:id "CHEBI:17996" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chloride" ; rdfs:subClassOf obo:CHEBI_16042, obo:CHEBI_33432, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17883 ] . obo:CHEBI_18059 obo:IAO_0000115 "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." ; oboInOwl:hasAlternativeId "CHEBI:14517", "CHEBI:25054", "CHEBI:6486" ; oboInOwl:hasDbXref "KEGG:C01356" ; oboInOwl:hasExactSynonym "Lipid", "lipid", "lipids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:18059" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "lipid" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_18085 obo:IAO_0000115 "Any polysaccharide containing a substantial proportion of aminomonosaccharide residues." ; oboInOwl:hasAlternativeId "CHEBI:14361", "CHEBI:24398", "CHEBI:5495" ; oboInOwl:hasDbXref "KEGG:C02545", "Wikipedia:Glycosaminoglycan" ; oboInOwl:hasExactSynonym "Glycosaminoglycan", "glycosaminoglycan" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Glykosaminoglykan", "glicosaminoglicano", "glycosaminoglycane", "glycosaminoglycans" ; oboInOwl:id "CHEBI:18085" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycosaminoglycan" ; rdfs:subClassOf obo:CHEBI_22506 . obo:CHEBI_18099 obo:IAO_0000115 "An alcohol that consists of cyclohexane bearing a single hydroxy substituent. The parent of the class of cyclohexanols." ; chebi:charge "0" ; chebi:formula "C6H12O" ; chebi:inchi "InChI=1S/C6H12O/c7-6-4-2-1-3-5-6/h6-7H,1-5H2" ; chebi:inchikey "HPXRVTGHNJAIIH-UHFFFAOYSA-N" ; chebi:mass "100.15888" ; chebi:monoisotopicmass "100.08882" ; chebi:smiles "OC1CCCCC1" ; oboInOwl:hasAlternativeId "CHEBI:14051", "CHEBI:23471", "CHEBI:4013", "CHEBI:41739" ; oboInOwl:hasDbXref "CAS:108-93-0", "DrugBank:DB03703", "KEGG:C00854", "MetaCyc:CYCLOHEXANOL", "PDBeChem:CXL", "PMID:11682644", "PMID:23825601", "Reaxys:906744", "UM-BBD_compID:c0175", "Wikipedia:Cyclohexanol" ; oboInOwl:hasExactSynonym "Cyclohexanol", "cyclohexanol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-Cyclohexanol", "Cyclohexan-1-ol", "Cyclohexyl alcohol", "Hexahydrophenol", "Hexalin", "Hydrophenol", "Hydroxycyclohexane" ; oboInOwl:id "CHEBI:18099" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclohexanol" ; rdfs:subClassOf obo:CHEBI_23480, obo:CHEBI_35681, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ] . obo:CHEBI_18133 obo:IAO_0000115 "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." ; oboInOwl:hasAlternativeId "CHEBI:14399", "CHEBI:24590", "CHEBI:5709" ; oboInOwl:hasDbXref "GlyGen:G70994MS", "GlyTouCan:G70994MS", "KEGG:C00738" ; oboInOwl:hasExactSynonym "Hexose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/", "hexoses" ; oboInOwl:id "CHEBI:18133" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hexose" ; rdfs:subClassOf obo:CHEBI_35381 . obo:CHEBI_18140 chebi:charge "0" ; chebi:formula "HX" ; chebi:mass "1.008" ; chebi:monoisotopicmass "1.00783" ; chebi:smiles "[F,Cl,Br,I]" ; oboInOwl:hasAlternativeId "CHEBI:13368", "CHEBI:37140", "CHEBI:5599" ; oboInOwl:hasExactSynonym "hydrogen halide", "hydrogen halides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HX", "hydrogen halides" ; oboInOwl:id "CHEBI:18140" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogen halide" ; rdfs:subClassOf obo:CHEBI_33405, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138103 ] . obo:CHEBI_18154 obo:IAO_0000115 "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." ; oboInOwl:hasAlternativeId "CHEBI:14864", "CHEBI:26205", "CHEBI:8322" ; oboInOwl:hasDbXref "KEGG:C00420" ; oboInOwl:hasExactSynonym "Polysaccharide", "polysaccharides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Glycan", "Glycane", "Glykan", "Glykane", "glycans", "polisacarido", "polisacaridos" ; oboInOwl:id "CHEBI:18154" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polysaccharide" ; rdfs:subClassOf obo:CHEBI_16646, obo:CHEBI_167559, obo:CHEBI_33694 . obo:CHEBI_18179 obo:IAO_0000115 "Any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol." ; oboInOwl:hasAlternativeId "CHEBI:14806", "CHEBI:60751", "CHEBI:8132" ; oboInOwl:hasDbXref "PMID:10782093", "PMID:15269334", "PMID:17035995", "PMID:19154715" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:18179" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphoinositide" ; rdfs:subClassOf obo:CHEBI_28874 . obo:CHEBI_18243 obo:IAO_0000115 "Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group." ; chebi:charge "0" ; chebi:formula "C8H11NO2" ; chebi:inchi "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2" ; chebi:inchikey "VYFYYTLLBUKUHU-UHFFFAOYSA-N" ; chebi:mass "153.17840" ; chebi:monoisotopicmass "153.07898" ; chebi:smiles "NCCc1ccc(O)c(O)c1" ; oboInOwl:hasAlternativeId "CHEBI:11695", "CHEBI:11930", "CHEBI:14203", "CHEBI:1764", "CHEBI:23886", "CHEBI:43686" ; oboInOwl:hasDbXref "CAS:51-61-6", "DrugBank:DB00988", "Drug_Central:947", "HMDB:HMDB0000073", "KEGG:C03758", "KEGG:D07870", "KNApSAcK:C00001408", "LINCS:LSM-4630", "MetaCyc:DOPAMINE", "PMID:10629745", "PMID:11149432", "PMID:9422813", "Reaxys:1072822", "Wikipedia:Dopamine" ; oboInOwl:hasExactSynonym "4-(2-aminoethyl)benzene-1,2-diol", "Dopamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-(3,4-Dihydroxyphenyl)ethylamine", "2-(3,4-dihydroxyphenyl)ethylamine", "3,4-Dihydroxyphenethylamine", "3-Hydroxytyramine", "4-(2-Aminoethyl)-1,2-benzenediol", "4-(2-Aminoethyl)benzene-1,2-diol", "4-(2-aminoethyl)-1,2-benzenediol", "4-(2-aminoethyl)catechol", "4-(2-aminoethyl)pyrocatechol", "Deoxyepinephrine", "Hydroxytyramin", "dopamina", "dopamine", "dopaminum" ; oboInOwl:id "CHEBI:18243" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dopamine" ; rdfs:subClassOf obo:CHEBI_33567, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35522 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35524 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38147 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48560 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_59905 ] . obo:CHEBI_18248 obo:IAO_0000115 "An iron group element atom that has atomic number 26." ; chebi:charge "0" ; chebi:formula "Fe" ; chebi:inchi "InChI=1S/Fe" ; chebi:inchikey "XEEYBQQBJWHFJM-UHFFFAOYSA-N" ; chebi:mass "55.84500" ; chebi:monoisotopicmass "55.93494" ; chebi:smiles "[Fe]" ; oboInOwl:hasAlternativeId "CHEBI:13322", "CHEBI:24872", "CHEBI:5974" ; oboInOwl:hasDbXref "CAS:7439-89-6", "DrugBank:DB01592", "HMDB:HMDB0015531", "KEGG:C00023", "Reaxys:4122945", "WebElements:Fe" ; oboInOwl:hasExactSynonym "iron" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "26Fe", "Eisen", "Fe", "Iron", "fer", "ferrum", "hierro", "iron" ; oboInOwl:id "CHEBI:18248" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iron atom" ; rdfs:subClassOf obo:CHEBI_33356, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_18254 obo:IAO_0000115 "Any nucleoside where the sugar component is D-ribose." ; chebi:charge "0" ; chebi:formula "C5H9O4R" ; chebi:mass "133.123" ; chebi:monoisotopicmass "133.05008" ; chebi:smiles "OC[C@H]1O[C@@H]([*])[C@H](O)[C@@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:13014", "CHEBI:13015", "CHEBI:13685", "CHEBI:21085", "CHEBI:26560", "CHEBI:4240", "CHEBI:8844" ; oboInOwl:hasDbXref "KEGG:C00911" ; oboInOwl:hasExactSynonym "Ribonucleoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a ribonucleoside", "ribonucleosides" ; oboInOwl:id "CHEBI:18254" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribonucleoside" ; rdfs:subClassOf obo:CHEBI_33838, obo:CHEBI_47019 . obo:CHEBI_18282 obo:IAO_0000115 "That part of DNA or RNA that may be involved in pairing." ; oboInOwl:hasAlternativeId "CHEBI:13873", "CHEBI:25598", "CHEBI:2995" ; oboInOwl:hasDbXref "KEGG:C00701", "Wikipedia:Nucleobase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Base", "nucleobases" ; oboInOwl:id "CHEBI:18282" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleobase" ; rdfs:subClassOf obo:CHEBI_38101 . obo:CHEBI_18291 chebi:charge "0" ; chebi:formula "Mn" ; chebi:inchi "InChI=1S/Mn" ; chebi:inchikey "PWHULOQIROXLJO-UHFFFAOYSA-N" ; chebi:mass "54.93805" ; chebi:monoisotopicmass "54.93804" ; chebi:smiles "[Mn]" ; oboInOwl:hasAlternativeId "CHEBI:13382", "CHEBI:25153", "CHEBI:6681" ; oboInOwl:hasDbXref "CAS:7439-96-5", "KEGG:C00034", "WebElements:Mn" ; oboInOwl:hasExactSynonym "manganese" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "25Mn", "Mangan", "Manganese", "Mn", "manganese", "manganeso", "manganum" ; oboInOwl:id "CHEBI:18291" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "manganese atom" ; rdfs:subClassOf obo:CHEBI_33352, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_18310 obo:IAO_0000115 "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms." ; chebi:charge "0" ; chebi:formula "CH3R" ; chebi:mass "15.035" ; chebi:monoisotopicmass "15.02348" ; chebi:smiles "C[*]" ; oboInOwl:hasAlternativeId "CHEBI:13435", "CHEBI:22317", "CHEBI:2576" ; oboInOwl:hasDbXref "KEGG:C01371" ; oboInOwl:hasExactSynonym "Alkane", "alkane", "alkanes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Alkan", "RH", "alcane", "alcanes", "alcano", "alcanos", "an alkane" ; oboInOwl:id "CHEBI:18310" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkane" ; rdfs:subClassOf obo:CHEBI_24632, obo:CHEBI_33653 . obo:CHEBI_18357 obo:IAO_0000115 "The R-enantiomer of noradrenaline." ; chebi:charge "0" ; chebi:formula "C8H11NO3" ; chebi:inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1" ; chebi:inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-N" ; chebi:mass "169.17780" ; chebi:monoisotopicmass "169.07389" ; chebi:smiles "NC[C@H](O)c1ccc(O)c(O)c1" ; oboInOwl:hasAlternativeId "CHEBI:1", "CHEBI:14668", "CHEBI:25592", "CHEBI:258884", "CHEBI:43725" ; oboInOwl:hasDbXref "Beilstein:2804840", "Beilstein:4231961", "CAS:51-41-2", "DrugBank:DB00368", "Drug_Central:1960", "HMDB:HMDB0000216", "KEGG:C00547", "KEGG:D00076", "KNApSAcK:C00001424", "PDBeChem:LNR", "Reaxys:2804840", "Wikipedia:Norepinephrine" ; oboInOwl:hasExactSynonym "4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-arterenol", "(-)-noradrenaline", "(-)-norepinephrine", "(R)-(-)-norepinephrine", "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol", "(R)-norepinephrine", "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol", "Arterenol", "L-NOREPINEPHRINE", "L-Noradrenaline", "Noradrenaline", "Norepinephrine", "norepinefrina", "norepinephrine", "norepinephrinum" ; oboInOwl:id "CHEBI:18357" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(R)-noradrenaline" ; rdfs:subClassOf obo:CHEBI_33569, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25512 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35524 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35569 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50514 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_72587 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_33571 ] . obo:CHEBI_18367 obo:IAO_0000115 "A phosphate ion that is the conjugate base of hydrogenphosphate." ; chebi:charge "-3" ; chebi:formula "O4P" ; chebi:inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3" ; chebi:inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-K" ; chebi:mass "94.97136" ; chebi:monoisotopicmass "94.95507" ; chebi:smiles "[O-]P([O-])([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:14791", "CHEBI:45024", "CHEBI:7793" ; oboInOwl:hasDbXref "Beilstein:3903772", "CAS:14265-44-2", "Gmelin:1997", "KEGG:C00009", "PDBeChem:PO4", "Reaxys:3903772" ; oboInOwl:hasExactSynonym "phosphate", "tetraoxidophosphate(3-)", "tetraoxophosphate(3-)", "tetraoxophosphate(V)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Orthophosphate", "PHOSPHATE ION", "PO4(3-)", "Phosphate", "[PO4](3-)" ; oboInOwl:id "CHEBI:18367" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphate(3-)" ; rdfs:subClassOf obo:CHEBI_35780, obo:CHEBI_79387, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_43474 ] . obo:CHEBI_18375 obo:IAO_0000115 "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-3 and C-5 of the ribose ring are engaged in formation of a cyclic mono-, di-, tri- or tetra-phosphate." ; chebi:charge "0" ; chebi:formula "C5H7O5PR2" ; chebi:mass "178.07980" ; chebi:monoisotopicmass "178.00311" ; chebi:smiles "OP1(=O)OC[C@H]2O[C@@H]([*])[C@H]([*])[C@@H]2O1" ; oboInOwl:hasAlternativeId "CHEBI:1331", "CHEBI:14672", "CHEBI:19833" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleoside 3',5'-cyclic phosphates" ; oboInOwl:id "CHEBI:18375" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside 3',5'-cyclic phosphate" ; rdfs:subClassOf obo:CHEBI_23447, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58464 ] . obo:CHEBI_18723 obo:IAO_0000115 "A racemate composed of equimolar amounts of (R)- and (S)-nicotine." ; oboInOwl:hasDbXref "Beilstein:82108", "Beilstein:82111", "CAS:22083-74-5", "DrugBank:DB00184", "HMDB:HMDB0014330", "KEGG:C16150", "KNApSAcK:C00002057", "PMID:10751565", "PMID:11192937", "PMID:11471991", "PMID:11559179", "PMID:11682702", "PMID:11714820", "PMID:11719700", "PMID:11801622", "PMID:11818389", "PMID:11860617", "PMID:12197757", "PMID:12700710", "PMID:12965231", "PMID:14715938", "PMID:15183514", "PMID:15251917", "PMID:15313135", "PMID:15458549", "PMID:15707677", "PMID:15894687", "PMID:15960296", "PMID:15961264", "PMID:16496293", "PMID:16950410", "PMID:17167832", "PMID:17206646", "PMID:17438652", "PMID:17498149", "PMID:17942810", "PMID:18077004", "PMID:18311975", "PMID:18380035", "PMID:18383130", "PMID:18651995", "PMID:18922921", "PMID:19100331", "PMID:19287496", "PMID:19389046", "PMID:19465085", "PMID:20338106", "PMID:20528766", "PMID:21636612", "PMID:21822688", "PMID:21945235", "PMID:22129149", "PMID:22218403", "PMID:22331007", "PMID:22377934", "PMID:22448647", "PMID:22459798", "PMID:22529223", "PMID:22573728", "PMID:22585541", "PMID:22589423", "PMID:22770225", "PMID:22792725", "PMID:22855884", "PMID:22930863", "PMID:22935730", "PMID:23108361", "PMID:23117126", "PMID:7097594", "PMID:7564279", "PMID:7566693", "PMID:7807214", "PMID:7896575", "PMID:8156919", "PMID:8545712", "PMID:8764340", "PMID:9203638", "PMID:9450943", "PMID:9621392", "Reaxys:82108", "UM-BBD_compID:c0468", "Wikipedia:Nicotine" ; oboInOwl:hasExactSynonym "rac-3-(1-methylpyrrolidin-2-yl)pyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine", "(+-)-nicotine", "(R,S)-nicotine", "(RS)-nicotine", "nicotin", "nikotin" ; oboInOwl:id "CHEBI:18723" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nicotine" ; rdfs:subClassOf obo:CHEBI_60911, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17688 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_39162 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35474 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_47958 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_49110 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50846 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_52290 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59163 ] . obo:CHEBI_19129 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "11alpha-hydroxy steroids" ; oboInOwl:id "CHEBI:19129" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "11alpha-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_36841 . obo:CHEBI_193111 obo:IAO_0000115 "The conjugate base of methylcarbamic acid; major microspecies at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C2H4NO2" ; chebi:inchi "InChI=1S/C2H5NO2/c1-3-2(4)5/h3H,1H3,(H,4,5)/p-1" ; chebi:inchikey "UFEJKYYYVXYMMS-UHFFFAOYSA-M" ; chebi:mass "74.060" ; chebi:monoisotopicmass "74.02475" ; chebi:smiles "CNC([O-])=O" ; oboInOwl:hasDbXref "MetaCyc:CPD-22706" ; oboInOwl:hasExactSynonym "methylcarbamate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-methyl carbamate", "N-methylcarbamate" ; oboInOwl:id "CHEBI:193111" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "methylcarbamate" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_13941 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_45379 ] . obo:CHEBI_194338 obo:IAO_0000115 "Any agent that interferes with the activity of T-type calcium channels." ; oboInOwl:hasDbXref "PMID:30372652", "PMID:36738196", "Wikipedia:T-type_calcium_channel" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "T-type calcium channel antagonist", "T-type calcium channel antagonists", "T-type calcium channel blockers" ; oboInOwl:id "CHEBI:194338" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "T-type calcium channel blocker" ; rdfs:subClassOf obo:CHEBI_38215 . obo:CHEBI_19834 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3',5'-cyclic purine nucleotides" ; oboInOwl:id "CHEBI:19834" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "3',5'-cyclic purine nucleotide" ; rdfs:subClassOf obo:CHEBI_18375, obo:CHEBI_36982 . obo:CHEBI_20664 chebi:charge "0" ; chebi:formula "C24H42" ; chebi:inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18+,19+,20-,21+,22+,23+,24-/m1/s1" ; chebi:inchikey "QSHQKIURKJITMZ-OBUPQJQESA-N" ; chebi:mass "330.59028" ; chebi:monoisotopicmass "330.32865" ; chebi:smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC" ; oboInOwl:hasDbXref "Beilstein:2048472" ; oboInOwl:hasExactSynonym "5beta-cholane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:20664" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "5beta-cholane" ; rdfs:subClassOf obo:CHEBI_35519 . obo:CHEBI_20702 obo:IAO_0000115 "Any aminopurine having the amino substituent at the 2-position." ; oboInOwl:hasExactSynonym "2-aminopurines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:20702" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "2-aminopurines" ; rdfs:subClassOf obo:CHEBI_22527 . obo:CHEBI_20706 obo:IAO_0000115 "Any compound having 6-aminopurine (adenine) as part of its structure." ; oboInOwl:hasDbXref "PMID:1646334", "PMID:18524423", "PMID:7342604" ; oboInOwl:hasExactSynonym "6-aminopurines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:20706" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "6-aminopurines" ; rdfs:subClassOf obo:CHEBI_22527 . obo:CHEBI_21731 obo:IAO_0000115 "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond." ; oboInOwl:hasExactSynonym "glycosylamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-glycoside", "N-glycosides", "N-glycosyl compounds", "glycosylamines" ; oboInOwl:id "CHEBI:21731" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "N-glycosyl compound" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_63161 . obo:CHEBI_22153 obo:IAO_0000115 "A substance used to destroy pests of the subclass Acari (mites and ticks)." ; oboInOwl:hasDbXref "Wikipedia:Acaricide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Akarizid", "Akarizide", "acaricides", "miticide" ; oboInOwl:id "CHEBI:22153" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acaricide" ; rdfs:subClassOf obo:CHEBI_25944 . obo:CHEBI_22160 obo:IAO_0000115 "Compounds with the general formula RNHC(=O)CH3." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22160" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acetamides" ; rdfs:subClassOf obo:CHEBI_37622 . obo:CHEBI_22221 obo:IAO_0000115 "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." ; oboInOwl:hasExactSynonym "acyl group", "alkanoyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acyl groups", "alkanoyl group", "groupe acyle" ; oboInOwl:id "CHEBI:22221" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acyl group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_22256 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenosine phosphates" ; oboInOwl:id "CHEBI:22256" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adenosine phosphate" ; rdfs:subClassOf obo:CHEBI_61296, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16335 ] . obo:CHEBI_22260 obo:IAO_0000115 "Any purine ribonucleoside that is a derivative of adenosine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22260" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adenosines" ; rdfs:subClassOf obo:CHEBI_26399, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16708 ] . obo:CHEBI_22307 obo:IAO_0000115 "Oximes of aldehydes RCH=NOH." ; chebi:charge "0" ; chebi:formula "CH2NOR" ; chebi:mass "44.03270" ; chebi:monoisotopicmass "44.01364" ; chebi:smiles "[H]C([*])=NO" ; oboInOwl:hasDbXref "KEGG:C02658" ; oboInOwl:hasExactSynonym "aldoxime", "aldoximes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldoximes" ; oboInOwl:id "CHEBI:22307" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aldoxime" ; rdfs:subClassOf obo:CHEBI_25750 . obo:CHEBI_22313 oboInOwl:hasExactSynonym "alkaline earth metals" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Erdalkalimetall", "Erdalkalimetalle", "alkaline earth metal", "alkaline-earth metal", "alkaline-earth metals", "metal alcalino-terreux", "metal alcalinoterreo", "metales alcalinoterreos", "metaux alcalino-terreux" ; oboInOwl:id "CHEBI:22313" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkaline earth metal atom" ; rdfs:subClassOf obo:CHEBI_33318, obo:CHEBI_33521, obo:CHEBI_33559 . obo:CHEBI_22314 oboInOwl:hasExactSynonym "alkali metals" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Alkalimetall", "Alkalimetalle", "alkali metal", "metal alcalin", "metal alcalino", "metales alcalinos", "metaux alcalins" ; oboInOwl:id "CHEBI:22314" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkali metal atom" ; rdfs:subClassOf obo:CHEBI_33318, obo:CHEBI_33521, obo:CHEBI_33559 . obo:CHEBI_22315 obo:IAO_0000115 "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." ; oboInOwl:hasDbXref "Wikipedia:Alkaloid" ; oboInOwl:hasExactSynonym "Alkaloid", "alkaloids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Alkaloide", "alcaloide", "alcaloides" ; oboInOwl:id "CHEBI:22315" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkaloid" ; rdfs:subClassOf obo:CHEBI_35352, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25212 ] . obo:CHEBI_22323 obo:IAO_0000115 "A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom." ; oboInOwl:hasExactSynonym "alkyl group", "alkyl groups" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "groupe alkyle", "grupo alquilo", "grupos alquilo" ; oboInOwl:id "CHEBI:22323" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkyl group" ; rdfs:subClassOf obo:CHEBI_33248, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_18310 ] . obo:CHEBI_22327 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aliphatic thioether", "aliphatic thioethers" ; oboInOwl:id "CHEBI:22327" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aliphatic sulfide" ; rdfs:subClassOf obo:CHEBI_16385 . obo:CHEBI_22333 obo:IAO_0000115 "Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22333" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkylating agent" ; rdfs:subClassOf obo:CHEBI_25435 . obo:CHEBI_22478 obo:IAO_0000115 "An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino alcohols", "aminoalcohol", "aminoalcohols" ; oboInOwl:id "CHEBI:22478" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amino alcohol" ; rdfs:subClassOf obo:CHEBI_30879, obo:CHEBI_50047 . obo:CHEBI_22506 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aminoglycans" ; oboInOwl:id "CHEBI:22506" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aminoglycan" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_65212 . obo:CHEBI_22527 obo:IAO_0000115 "Any purine having at least one amino substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aminopurines" ; oboInOwl:id "CHEBI:22527" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aminopurine" ; rdfs:subClassOf obo:CHEBI_26401 . obo:CHEBI_22562 obo:IAO_0000115 "Any aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22562" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anilines" ; rdfs:subClassOf obo:CHEBI_22712, obo:CHEBI_33860 . obo:CHEBI_22563 obo:IAO_0000115 "A monoatomic or polyatomic species having one or more elementary charges of the electron." ; oboInOwl:hasExactSynonym "Anion", "anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Anionen", "aniones", "anions" ; oboInOwl:id "CHEBI:22563" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anion" ; rdfs:subClassOf obo:CHEBI_24870 . obo:CHEBI_22586 obo:IAO_0000115 "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antioxidants", "antioxydant", "antoxidant" ; oboInOwl:id "CHEBI:22586" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antioxidant" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_22587 obo:IAO_0000115 "A substance that destroys or inhibits replication of viruses." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-viral agent", "anti-viral agents", "antiviral", "antiviral agents", "antivirals" ; oboInOwl:id "CHEBI:22587" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antiviral agent" ; rdfs:subClassOf obo:CHEBI_33281 . obo:CHEBI_22632 oboInOwl:hasExactSynonym "arsenic molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "arsenic compounds", "arsenic molecular entities" ; oboInOwl:id "CHEBI:22632" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "arsenic molecular entity" ; rdfs:subClassOf obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_27563 ] . obo:CHEBI_22633 obo:IAO_0000115 "An arsenic oxoanion resulting from the removal of one or more protons from arsenous acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "arsenite anions", "arsenite ions" ; oboInOwl:id "CHEBI:22633" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "arsenite ion" ; rdfs:subClassOf obo:CHEBI_24834, obo:CHEBI_35776 . obo:CHEBI_22695 obo:IAO_0000115 "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." ; oboInOwl:hasDbXref "KEGG:C00701" ; oboInOwl:hasExactSynonym "Base", "base" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Base1", "Base2", "Basen", "Nucleobase", "bases" ; oboInOwl:id "CHEBI:22695" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "base" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_22698 obo:IAO_0000115 "Any arenecarbaldehyde that consists of a formyl substituted benzene ring and its substituted derivatives thereof." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22698" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "benzaldehydes" ; rdfs:subClassOf obo:CHEBI_33855 . obo:CHEBI_22712 obo:IAO_0000115 "Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22712" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "benzenes" ; rdfs:subClassOf obo:CHEBI_33836 . obo:CHEBI_22728 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "benzopyrroles" ; oboInOwl:id "CHEBI:22728" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "benzopyrrole" ; rdfs:subClassOf obo:CHEBI_27171, obo:CHEBI_38101, obo:CHEBI_38180 . obo:CHEBI_22868 obo:IAO_0000115 "A sodium salt of the conjugate of any bile acid with either glycine or taurine." ; oboInOwl:hasDbXref "KEGG:C01558" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bile acid", "bile salts" ; oboInOwl:id "CHEBI:22868" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bile salt" ; rdfs:subClassOf obo:CHEBI_36078, obo:CHEBI_38700 . obo:CHEBI_22901 obo:IAO_0000115 "By usage, the methylenediphenols, HOC6H4CH2C6H4OH, commonly p,p-methylenediphenol, and their substitution products (generally derived from condensation of two equivalent amounts of a phenol with an aldehyde or ketone). The term also includes analogues in the the methylene (or substituted methylene) group has been replaced by a heteroatom." ; oboInOwl:hasDbXref "Wikipedia:Bisphenol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bisphenols" ; oboInOwl:id "CHEBI:22901" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bisphenol" ; rdfs:subClassOf obo:CHEBI_33853 . obo:CHEBI_22917 obo:IAO_0000115 "An insecticide compound naturally occurring in plants." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "botanical insecticide", "botanical insecticides", "phytogenic insecticides" ; oboInOwl:id "CHEBI:22917" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phytogenic insecticide" ; rdfs:subClassOf obo:CHEBI_24852 . obo:CHEBI_22927 chebi:charge "0" ; chebi:formula "Br" ; chebi:inchi "InChI=1S/Br" ; chebi:inchikey "WKBOTKDWSSQWDR-UHFFFAOYSA-N" ; chebi:mass "79.90400" ; chebi:monoisotopicmass "78.91834" ; chebi:smiles "[Br]" ; oboInOwl:hasDbXref "WebElements:Br" ; oboInOwl:hasExactSynonym "bromine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "35Br", "Br", "Brom", "brome", "bromine", "bromo", "bromum" ; oboInOwl:id "CHEBI:22927" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bromine atom" ; rdfs:subClassOf obo:CHEBI_24473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_22928 oboInOwl:hasExactSynonym "bromine molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bromine compounds", "bromine molecular entities" ; oboInOwl:id "CHEBI:22928" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bromine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22927 ] . obo:CHEBI_22951 obo:IAO_0000115 "Any ketone that is butane substituted by an oxo group at unspecified position." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "butanones" ; oboInOwl:id "CHEBI:22951" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "butanone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_22977 chebi:charge "0" ; chebi:formula "Cd" ; chebi:inchi "InChI=1S/Cd" ; chebi:inchikey "BDOSMKKIYDKNTQ-UHFFFAOYSA-N" ; chebi:mass "112.41100" ; chebi:monoisotopicmass "113.90336" ; chebi:smiles "[Cd]" ; oboInOwl:hasDbXref "CAS:7440-43-9", "KEGG:C01413", "WebElements:Cd" ; oboInOwl:hasExactSynonym "cadmium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "48Cd", "Cd", "Kadmium", "cadmio", "cadmium" ; oboInOwl:id "CHEBI:22977" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cadmium atom" ; rdfs:subClassOf obo:CHEBI_33340 . obo:CHEBI_22984 chebi:charge "0" ; chebi:formula "Ca" ; chebi:inchi "InChI=1S/Ca" ; chebi:inchikey "OYPRJOBELJOOCE-UHFFFAOYSA-N" ; chebi:mass "40.07800" ; chebi:monoisotopicmass "39.96259" ; chebi:smiles "[Ca]" ; oboInOwl:hasDbXref "CAS:7440-70-2", "DrugBank:DB01373", "KEGG:C00076", "WebElements:Ca" ; oboInOwl:hasExactSynonym "calcium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "20Ca", "Ca", "Calcium", "Kalzium", "calcio", "calcium" ; oboInOwl:id "CHEBI:22984" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "calcium atom" ; rdfs:subClassOf obo:CHEBI_22313, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_22985 oboInOwl:hasExactSynonym "calcium molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium compounds", "calcium molecular entities" ; oboInOwl:id "CHEBI:22985" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "calcium molecular entity" ; rdfs:subClassOf obo:CHEBI_33299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22984 ] . obo:CHEBI_23003 obo:IAO_0000115 "Any ester of carbamic acid or its N-substituted derivatives." ; oboInOwl:hasDbXref "Wikipedia:Carbamate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbamate esters", "carbamates" ; oboInOwl:id "CHEBI:23003" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbamate ester" ; rdfs:subClassOf obo:CHEBI_33308, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_28616 ] . obo:CHEBI_23004 obo:IAO_0000115 "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." ; chebi:charge "0" ; chebi:formula "CH2NO" ; chebi:mass "44.03272" ; chebi:monoisotopicmass "44.01364" ; chebi:smiles "*C(N)=O" ; oboInOwl:hasDbXref "PMID:24168430" ; oboInOwl:hasExactSynonym "carbamoyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-C(O)NH2", "-CONH2", "aminocarbonyl", "carbamyl", "carbamyl group", "carboxamide" ; oboInOwl:id "CHEBI:23004" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbamoyl group" ; rdfs:subClassOf obo:CHEBI_27207, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_28616 ] . obo:CHEBI_23014 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon oxides", "oxides of carbon" ; oboInOwl:id "CHEBI:23014" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbon oxide" ; rdfs:subClassOf obo:CHEBI_25701, obo:CHEBI_36963 . obo:CHEBI_23019 chebi:charge "0" ; chebi:formula "CO" ; chebi:mass "28.01010" ; chebi:monoisotopicmass "27.99491" ; chebi:smiles "O=C(*)*" ; oboInOwl:hasExactSynonym "carbonyl", "carbonyl group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym ">C=O" ; oboInOwl:id "CHEBI:23019" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbonyl group" ; rdfs:subClassOf obo:CHEBI_51422 . obo:CHEBI_23114 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chloride salts", "chlorides" ; oboInOwl:id "CHEBI:23114" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chloride salt" ; rdfs:subClassOf obo:CHEBI_23117, obo:CHEBI_33958, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17996 ] . obo:CHEBI_23116 chebi:charge "0" ; chebi:formula "Cl" ; chebi:inchi "InChI=1S/Cl" ; chebi:inchikey "ZAMOUSCENKQFHK-UHFFFAOYSA-N" ; chebi:mass "35.45270" ; chebi:monoisotopicmass "34.96885" ; chebi:smiles "[Cl]" ; oboInOwl:hasDbXref "WebElements:Cl" ; oboInOwl:hasExactSynonym "chlorine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "17Cl", "Chlor", "Cl", "chlore", "chlorine", "chlorum", "cloro" ; oboInOwl:id "CHEBI:23116" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chlorine atom" ; rdfs:subClassOf obo:CHEBI_24473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_23117 obo:IAO_0000115 "A halogen molecular entity containing one or more atoms of chlorine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23117" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chlorine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_23116 ] . obo:CHEBI_23357 obo:IAO_0000115 "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." ; oboInOwl:hasDbXref "Wikipedia:Cofactor_(biochemistry)" ; oboInOwl:hasExactSynonym "cofactor", "cofactors" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23357" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cofactor" ; rdfs:subClassOf obo:CHEBI_52206 . obo:CHEBI_23359 obo:IAO_0000115 "An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum." ; chebi:charge "0" ; chebi:formula "C22H25NO6" ; chebi:inchi "InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)" ; chebi:inchikey "IAKHMKGGTNLKSZ-UHFFFAOYSA-N" ; chebi:mass "399.43704" ; chebi:monoisotopicmass "399.16819" ; chebi:smiles "COc1cc2CCC(NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC" ; oboInOwl:hasDbXref "Beilstein:2228812", "CAS:54192-66-4", "DrugBank:DB01394", "HMDB:HMDB0015466", "LINCS:LSM-6449", "PMID:10680067", "PMID:24074178", "PMID:7200520", "PMID:9819133", "Reaxys:2228812" ; oboInOwl:hasExactSynonym "N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23359" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "colchicine" ; rdfs:subClassOf obo:CHEBI_22160, obo:CHEBI_22315, obo:CHEBI_35618, obo:CHEBI_38032, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_61951 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ] . obo:CHEBI_23367 obo:IAO_0000115 "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ; oboInOwl:hasExactSynonym "molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "entidad molecular", "entidades moleculares", "entite moleculaire", "molecular entities", "molekulare Entitaet" ; oboInOwl:id "CHEBI:23367" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "molecular entity" ; rdfs:subClassOf obo:CHEBI_24431 . obo:CHEBI_23377 oboInOwl:hasExactSynonym "copper molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "copper compounds", "copper molecular entities" ; oboInOwl:id "CHEBI:23377" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "copper molecular entity" ; rdfs:subClassOf obo:CHEBI_33745, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_28694 ] . obo:CHEBI_23423 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23423" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "pseudohalogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24833 . obo:CHEBI_23447 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic nucleotides" ; oboInOwl:id "CHEBI:23447" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic nucleotide" ; rdfs:subClassOf obo:CHEBI_36976 . obo:CHEBI_23449 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cyclopeptid", "Zyklopeptid", "cyclic peptides", "peptide cyclique", "peptido ciclico" ; oboInOwl:id "CHEBI:23449" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic peptide" ; rdfs:subClassOf obo:CHEBI_16670 . obo:CHEBI_23451 obo:IAO_0000115 "A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom." ; oboInOwl:hasExactSynonym "cyclitols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23451" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclitol" ; rdfs:subClassOf obo:CHEBI_26191 . obo:CHEBI_23480 obo:IAO_0000115 "An alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23480" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclohexanols" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_23493 obo:IAO_0000115 "Cyclopentane and its derivatives formed by substitution." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23493" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclopentanes" ; rdfs:subClassOf obo:CHEBI_33598 . obo:CHEBI_23495 obo:IAO_0000115 "An alcohol in which one or more hydroxy groups are attached to a cyclopentane skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23495" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclopentanols" ; rdfs:subClassOf obo:CHEBI_23493, obo:CHEBI_30879 . obo:CHEBI_23509 obo:IAO_0000115 "An amino acid derivative resulting from reaction of cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of cysteine by a heteroatom. The definition normally excludes peptides containing cysteine residues." ; oboInOwl:hasAlternativeId "CHEBI:25309" ; oboInOwl:hasExactSynonym "cysteine derivative" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cysteine derivatives" ; oboInOwl:id "CHEBI:23509" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cysteine derivative" ; rdfs:subClassOf obo:CHEBI_83821, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_15356 ] . obo:CHEBI_23677 obo:IAO_0000115 "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "diazoles" ; oboInOwl:id "CHEBI:23677" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diazole" ; rdfs:subClassOf obo:CHEBI_68452 . obo:CHEBI_237958 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:237958" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate" ; rdfs:subClassOf obo:CHEBI_37045, obo:CHEBI_37096, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50733 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_57299 ] . obo:CHEBI_23849 obo:IAO_0000115 "Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." ; oboInOwl:hasDbXref "LIPID_MAPS_class:LMPR0104" ; oboInOwl:hasExactSynonym "diterpenoids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C20 isoprenoids", "diterpenoides" ; oboInOwl:id "CHEBI:23849" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diterpenoid" ; rdfs:subClassOf obo:CHEBI_26873, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_35190 ] . obo:CHEBI_23888 obo:IAO_0000115 "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "drugs", "medicine" ; oboInOwl:id "CHEBI:23888" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "drug" ; rdfs:subClassOf obo:CHEBI_52217 . obo:CHEBI_23905 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic anions" ; oboInOwl:id "CHEBI:23905" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic anion" ; rdfs:subClassOf obo:CHEBI_22563, obo:CHEBI_24867 . obo:CHEBI_23906 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic cations" ; oboInOwl:id "CHEBI:23906" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic cation" ; rdfs:subClassOf obo:CHEBI_24867, obo:CHEBI_36916 . obo:CHEBI_23924 obo:IAO_0000115 "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." ; oboInOwl:hasExactSynonym "enzyme inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "enzyme inhibitors", "inhibidor enzimatico", "inhibidores enzimaticos", "inhibiteur enzymatique", "inhibiteurs enzymatiques" ; oboInOwl:id "CHEBI:23924" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "enzyme inhibitor" ; rdfs:subClassOf obo:CHEBI_35222, obo:CHEBI_52206 . obo:CHEBI_23981 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ethanolamine" ; oboInOwl:id "CHEBI:23981" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ethanolamines" ; rdfs:subClassOf obo:CHEBI_22478 . obo:CHEBI_23982 obo:IAO_0000115 "Any primary alcohol based on an ethanol skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23982" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ethanols" ; rdfs:subClassOf obo:CHEBI_15734 . obo:CHEBI_23994 obo:IAO_0000115 "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol." ; chebi:charge "0" ; chebi:formula "C3H8O3S" ; chebi:inchi "InChI=1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3" ; chebi:inchikey "PLUBXMRUUVWRLT-UHFFFAOYSA-N" ; chebi:mass "124.15900" ; chebi:monoisotopicmass "124.01942" ; chebi:smiles "CCOS(C)(=O)=O" ; oboInOwl:hasDbXref "CAS:62-50-0", "KEGG:C19239", "PMID:16039156", "PMID:19797863", "PMID:20102787", "PMID:24475756", "PMID:24524729", "PMID:24531730", "PMID:24728647", "PMID:6936603", "PMID:7285888", "Reaxys:773969", "Wikipedia:Ethyl_methanesulfonate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EMS", "ethyl mesylate", "ethyl methanesulphonate", "methylsulfonic acid ethyl ester", "methylsulfonic acid, ethyl ester" ; oboInOwl:id "CHEBI:23994" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ethyl methanesulfonate" ; rdfs:subClassOf obo:CHEBI_25223, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22333 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35610 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50903 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ] . obo:CHEBI_24026 obo:IAO_0000115 "An aliphatic alcohol consisting of a chain of 3 to greater than 27 carbon atoms. Fatty alcohols may be saturated or unsaturated and may be branched or unbranched." ; chebi:charge "0" ; chebi:formula "HOR" ; chebi:mass "17.007" ; chebi:monoisotopicmass "17.00274" ; chebi:smiles "O[*]" ; oboInOwl:hasDbXref "LIPID_MAPS_class:LMFA05", "MetaCyc:Fatty-Alcohols", "Wikipedia:Fatty_alcohol" ; oboInOwl:hasExactSynonym "fatty alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Fettalkohol", "Fettalkohole", "alcool gras", "fatty alcohols" ; oboInOwl:id "CHEBI:24026" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fatty alcohol" ; rdfs:subClassOf obo:CHEBI_30879, obo:CHEBI_61697 . obo:CHEBI_24061 chebi:charge "0" ; chebi:formula "F" ; chebi:inchi "InChI=1S/F" ; chebi:inchikey "YCKRFDGAMUMZLT-UHFFFAOYSA-N" ; chebi:mass "18.99840" ; chebi:monoisotopicmass "18.99840" ; chebi:smiles "[F]" ; oboInOwl:hasDbXref "CAS:7782-41-4", "WebElements:F" ; oboInOwl:hasExactSynonym "fluorine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "9F", "F", "Fluor", "fluor", "fluorine", "fluorum" ; oboInOwl:id "CHEBI:24061" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluorine atom" ; rdfs:subClassOf obo:CHEBI_24473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_24062 oboInOwl:hasExactSynonym "fluorine molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fluorine compounds", "fluorine molecular entities" ; oboInOwl:id "CHEBI:24062" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluorine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_24061 ] . obo:CHEBI_24067 obo:IAO_0000115 "A haloalkane that is an alkane in which at least one hydrogen atom has been replaced by a fluorine atom." ; oboInOwl:hasExactSynonym "fluoroalkane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fluoroalkanes" ; oboInOwl:id "CHEBI:24067" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluoroalkane" ; rdfs:subClassOf obo:CHEBI_24469, obo:CHEBI_37143 . obo:CHEBI_24129 obo:IAO_0000115 "Compounds containing at least one furan ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxacyclopenta-2,4-dienes" ; oboInOwl:id "CHEBI:24129" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "furans" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38104 . obo:CHEBI_24384 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24384" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycogens" ; rdfs:subClassOf obo:CHEBI_37163 . obo:CHEBI_24400 obo:IAO_0000115 "A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively." ; oboInOwl:hasExactSynonym "glycosides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "O-glycoside", "O-glycosides", "glycosides" ; oboInOwl:id "CHEBI:24400" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycoside" ; rdfs:subClassOf obo:CHEBI_63161 . obo:CHEBI_24431 obo:IAO_0000115 "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." ; oboInOwl:hasExactSynonym "chemical entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24431" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chemical entity" ; rdfs:subClassOf obo:BFO_0000040 . obo:CHEBI_24432 obo:IAO_0000115 "A role played by the molecular entity or part thereof within a biological context." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "biological function" ; oboInOwl:id "CHEBI:24432" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "biological role" ; rdfs:subClassOf obo:BFO_0000023, obo:CHEBI_50906 . obo:CHEBI_24433 obo:IAO_0000115 "A defined linked collection of atoms or a single atom within a molecular entity." ; oboInOwl:hasExactSynonym "group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Gruppe", "Rest", "groupe", "grupo", "grupos" ; oboInOwl:id "CHEBI:24433" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "group" ; rdfs:subClassOf obo:CHEBI_24431, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33250 ] . obo:CHEBI_24469 obo:IAO_0000115 "A halohydrocarbon that is an alkane in which at least one hydrogen atom has been replaced by with a halogen atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkyl halide", "alkyl halides", "haloalkanes" ; oboInOwl:id "CHEBI:24469" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "haloalkane" ; rdfs:subClassOf obo:CHEBI_24472 . obo:CHEBI_24471 oboInOwl:hasExactSynonym "halogen molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogen compounds", "halogen molecular entities" ; oboInOwl:id "CHEBI:24471" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_24473 ] . obo:CHEBI_24472 obo:IAO_0000115 "A compound derived from a hydrocarbon by replacing a hydrogen atom with a halogen atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogenated hydrocarbons", "halohydrocarbons" ; oboInOwl:id "CHEBI:24472" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halohydrocarbon" ; rdfs:subClassOf obo:CHEBI_17792, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_24632 ] . obo:CHEBI_24473 oboInOwl:hasExactSynonym "halogen", "halogens" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Halogene", "group 17 elements", "group VII elements", "halogene", "halogenes", "halogeno", "halogenos" ; oboInOwl:id "CHEBI:24473" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halogen" ; rdfs:subClassOf obo:CHEBI_25585, obo:CHEBI_33560 . obo:CHEBI_24527 obo:IAO_0000115 "A substance used to destroy plant pests." ; oboInOwl:hasDbXref "Wikipedia:Herbicide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Herbizid", "Unkrautbekaempfungsmittel", "Unkrautvertilgungsmittel", "Wildkrautbekaempfungsmittel", "herbicides" ; oboInOwl:id "CHEBI:24527" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "herbicide" ; rdfs:subClassOf obo:CHEBI_25944 . obo:CHEBI_24532 obo:IAO_0000115 "A cyclic compound having as ring members atoms of carbon and at least of one other element." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic heterocycle", "organic heterocyclic compounds" ; oboInOwl:id "CHEBI:24532" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic heterocyclic compound" ; rdfs:subClassOf obo:CHEBI_33285, obo:CHEBI_33832, obo:CHEBI_5686 . obo:CHEBI_24533 obo:IAO_0000115 "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." ; oboInOwl:hasExactSynonym "heterodetic cyclic peptide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterodetic cyclic peptides", "peptide cyclique heterodetique", "peptido ciclico heterodetico" ; oboInOwl:id "CHEBI:24533" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heterodetic cyclic peptide" ; rdfs:subClassOf obo:CHEBI_23449 . obo:CHEBI_24621 obo:IAO_0000115 "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "endocrine", "hormones" ; oboInOwl:id "CHEBI:24621" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hormone" ; rdfs:subClassOf obo:CHEBI_33280, obo:CHEBI_48705 . obo:CHEBI_24632 obo:IAO_0000115 "A compound consisting of carbon and hydrogen only." ; oboInOwl:hasExactSynonym "hydrocarbon", "hydrocarbons" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kohlenwasserstoff", "Kohlenwasserstoffe", "hidrocarburo", "hidrocarburos", "hydrocarbure" ; oboInOwl:id "CHEBI:24632" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrocarbon" ; rdfs:subClassOf obo:CHEBI_33245 . obo:CHEBI_24651 obo:IAO_0000115 "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24651" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydroxides" ; rdfs:subClassOf obo:CHEBI_25806, obo:CHEBI_33608, obo:CHEBI_37577, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_43176 ] . obo:CHEBI_24663 obo:IAO_0000115 "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydroxy-5beta-cholanic acids" ; oboInOwl:id "CHEBI:24663" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydroxy-5beta-cholanic acid" ; rdfs:subClassOf obo:CHEBI_33822, obo:CHEBI_36248, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_36238 ] . obo:CHEBI_24757 obo:IAO_0000115 "A chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water." ; chebi:charge "0" ; chebi:formula "ClHO" ; chebi:inchi "InChI=1S/ClHO/c1-2/h2H" ; chebi:inchikey "QWPPOHNGKGFGJK-UHFFFAOYSA-N" ; chebi:mass "52.46004" ; chebi:monoisotopicmass "51.97159" ; chebi:smiles "OCl" ; oboInOwl:hasDbXref "CAS:7790-92-3", "Gmelin:688", "PMID:11640916", "PMID:12079432", "PMID:12215218", "PMID:15589368", "PMID:7487057", "PMID:8072005" ; oboInOwl:hasExactSynonym "chloranol", "hydroxidochlorine", "hypochlorous acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Chlor(I)-saeure", "HClO", "HOCl", "[ClOH]", "hypochloric acid", "hypochlorige Saeure" ; oboInOwl:id "CHEBI:24757" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hypochlorous acid" ; rdfs:subClassOf obo:CHEBI_26523, obo:CHEBI_33426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38462 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76797 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29222 ] . obo:CHEBI_24780 obo:IAO_0000115 "A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24780" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "imidazoles" ; rdfs:subClassOf obo:CHEBI_23677 . obo:CHEBI_24782 oboInOwl:hasExactSynonym "imide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "imides" ; oboInOwl:id "CHEBI:24782" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "imide" ; rdfs:subClassOf obo:CHEBI_33257 . obo:CHEBI_24828 obo:IAO_0000115 "Any compound containing an indole skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24828" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "indoles" ; rdfs:subClassOf obo:CHEBI_22728 . obo:CHEBI_24833 obo:IAO_0000115 "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ; oboInOwl:hasExactSynonym "oxoacid", "oxoacids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxacids", "oxiacids", "oxo acid", "oxy-acids", "oxyacids" ; oboInOwl:id "CHEBI:24833" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxoacid" ; rdfs:subClassOf obo:CHEBI_24651, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39141 ] . obo:CHEBI_24834 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic anions" ; oboInOwl:id "CHEBI:24834" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic anion" ; rdfs:subClassOf obo:CHEBI_22563, obo:CHEBI_36914 . obo:CHEBI_24835 obo:IAO_0000115 "A molecular entity that contains no carbon." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anorganische Verbindungen", "inorganic compounds", "inorganic entity", "inorganic molecular entities", "inorganics" ; oboInOwl:id "CHEBI:24835" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic molecular entity" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_24836 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic oxides" ; oboInOwl:id "CHEBI:24836" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic oxide" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_25741 . obo:CHEBI_24837 obo:IAO_0000115 "Compounds of structure ROOR' in which R and R' are inorganic groups." ; oboInOwl:hasExactSynonym "inorganic peroxide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic peroxides" ; oboInOwl:id "CHEBI:24837" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic peroxide" ; rdfs:subClassOf obo:CHEBI_24836, obo:CHEBI_25940 . obo:CHEBI_24839 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anorganisches Salz", "inorganic salts" ; oboInOwl:id "CHEBI:24839" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic salt" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_24866 . obo:CHEBI_24848 obo:IAO_0000115 "Any cyclohexane-1,2,3,4,5,6-hexol." ; chebi:charge "0" ; chebi:formula "C6H12O6" ; chebi:inchi "InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H" ; chebi:inchikey "CDAISMWEOUEBRE-UHFFFAOYSA-N" ; chebi:mass "180.15588" ; chebi:monoisotopicmass "180.06339" ; chebi:smiles "OC1C(O)C(O)C(O)C(O)C1O" ; oboInOwl:hasExactSynonym "inositol", "inositols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2,3,4,5,6-cyclohexanehexol", "inositols" ; oboInOwl:id "CHEBI:24848" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inositol" ; rdfs:subClassOf obo:CHEBI_23451, obo:CHEBI_37206 . obo:CHEBI_24852 obo:IAO_0000115 "Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects." ; oboInOwl:hasDbXref "Wikipedia:Insecticide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "insecticides" ; oboInOwl:id "CHEBI:24852" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "insecticide" ; rdfs:subClassOf obo:CHEBI_25944 . obo:CHEBI_24858 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iodide salts", "iodides" ; oboInOwl:id "CHEBI:24858" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iodide salt" ; rdfs:subClassOf obo:CHEBI_24860, obo:CHEBI_33958, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16382 ] . obo:CHEBI_24859 obo:IAO_0000115 "Chemical element with atomic number 53." ; chebi:charge "0" ; chebi:formula "I" ; chebi:inchi "InChI=1S/I" ; chebi:inchikey "ZCYVEMRRCGMTRW-UHFFFAOYSA-N" ; chebi:mass "126.90447" ; chebi:monoisotopicmass "126.90447" ; chebi:smiles "[I]" ; oboInOwl:hasDbXref "WebElements:I" ; oboInOwl:hasExactSynonym "iodine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "53I", "I", "Iod", "J", "Jod", "iode", "iodine", "iodium", "yodo" ; oboInOwl:id "CHEBI:24859" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iodine atom" ; rdfs:subClassOf obo:CHEBI_24473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ] . obo:CHEBI_24860 oboInOwl:hasExactSynonym "iodine molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iodine compounds", "iodine molecular entities" ; oboInOwl:id "CHEBI:24860" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iodine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_24859 ] . obo:CHEBI_24866 obo:IAO_0000115 "A salt is an assembly of cations and anions." ; oboInOwl:hasExactSynonym "salt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Salz", "Salze", "ionic compound", "ionic compounds", "sal", "sales", "salts", "sel", "sels" ; oboInOwl:id "CHEBI:24866" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "salt" ; rdfs:subClassOf obo:CHEBI_37577, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22563 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_36916 ] . obo:CHEBI_24867 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic ions" ; oboInOwl:id "CHEBI:24867" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic ion" ; rdfs:subClassOf obo:CHEBI_24870, obo:CHEBI_33238 . obo:CHEBI_24868 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic salts", "organisches Salz" ; oboInOwl:id "CHEBI:24868" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic salt" ; rdfs:subClassOf obo:CHEBI_24866 . obo:CHEBI_24870 obo:IAO_0000115 "A molecular entity having a net electric charge." ; oboInOwl:hasExactSynonym "Ion", "ion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ionen", "iones", "ions" ; oboInOwl:id "CHEBI:24870" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ion" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_24873 oboInOwl:hasExactSynonym "iron molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iron compounds", "iron molecular entities" ; oboInOwl:id "CHEBI:24873" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iron molecular entity" ; rdfs:subClassOf obo:CHEBI_33744, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_18248 ] . obo:CHEBI_24913 obo:IAO_0000115 "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives." ; oboInOwl:hasDbXref "LIPID_MAPS_class:LMPR01", "PMID:12769708", "PMID:19219049" ; oboInOwl:hasExactSynonym "isoprenoid", "isoprenoids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isoprenoids" ; oboInOwl:id "CHEBI:24913" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isoprenoid" ; rdfs:subClassOf obo:CHEBI_18059 . obo:CHEBI_24921 obo:IAO_0000115 "Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isoquinoline alkaloids" ; oboInOwl:id "CHEBI:24921" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isoquinoline alkaloid" ; rdfs:subClassOf obo:CHEBI_22315 . obo:CHEBI_24922 obo:IAO_0000115 "A class of organic heteropolycyclic compound consisting of isoquinoline and its substitution derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24922" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isoquinolines" ; rdfs:subClassOf obo:CHEBI_38101, obo:CHEBI_38166 . obo:CHEBI_25000 obo:IAO_0000115 "Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." ; oboInOwl:hasExactSynonym "lactone", "lactones" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Lacton", "Lakton", "Laktone", "lactona", "lactonas" ; oboInOwl:id "CHEBI:25000" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "lactone" ; rdfs:subClassOf obo:CHEBI_33308, obo:CHEBI_38104 . obo:CHEBI_25016 chebi:charge "0" ; chebi:formula "Pb" ; chebi:inchi "InChI=1S/Pb" ; chebi:inchikey "WABPQHHGFIMREM-UHFFFAOYSA-N" ; chebi:mass "207.20000" ; chebi:monoisotopicmass "207.97665" ; chebi:smiles "[Pb]" ; oboInOwl:hasDbXref "KEGG:C06696", "WebElements:Pb" ; oboInOwl:hasExactSynonym "lead" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "82Pb", "Blei", "Pb", "lead", "plomb", "plomo", "plumbum" ; oboInOwl:id "CHEBI:25016" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "lead atom" ; rdfs:subClassOf obo:CHEBI_33306, obo:CHEBI_33521 . obo:CHEBI_25046 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:25046" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "linear tetrapyrrole" ; rdfs:subClassOf obo:CHEBI_26932 . obo:CHEBI_25094 obo:IAO_0000115 "A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6." ; chebi:charge "0" ; chebi:formula "C6H14N2O2" ; chebi:inchi "InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)" ; chebi:inchikey "KDXKERNSBIXSRK-UHFFFAOYSA-N" ; chebi:mass "146.18764" ; chebi:monoisotopicmass "146.10553" ; chebi:smiles "NCCCCC(N)C(O)=O" ; oboInOwl:hasDbXref "Beilstein:1616991", "CAS:70-54-2", "Gmelin:279284", "KEGG:C16440", "PMID:17439666", "PMID:22264337", "Reaxys:1616991", "Wikipedia:Lysine" ; oboInOwl:hasExactSynonym "2,6-diaminohexanoic acid", "lysine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "K", "LYS", "Lysin", "alpha,epsilon-diaminocaproic acid" ; oboInOwl:id "CHEBI:25094" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "lysine" ; rdfs:subClassOf obo:CHEBI_26167, obo:CHEBI_33704, obo:CHEBI_35987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50339 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_30776 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32563 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32564 ] . obo:CHEBI_25105 obo:IAO_0000115 "A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Makrolidantibiotika", "macrolide antibiotics" ; oboInOwl:id "CHEBI:25105" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "macrolide antibiotic" ; rdfs:subClassOf obo:CHEBI_25106, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_25106 obo:IAO_0000115 "A macrocyclic lactone with a ring of twelve or more members derived from a polyketide." ; oboInOwl:hasDbXref "Wikipedia:Macrolide" ; oboInOwl:hasExactSynonym "macrolide", "macrolides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Makrolid", "macrolides" ; oboInOwl:id "CHEBI:25106" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "macrolide" ; rdfs:subClassOf obo:CHEBI_26188, obo:CHEBI_63944 . obo:CHEBI_25107 chebi:charge "0" ; chebi:formula "Mg" ; chebi:inchi "InChI=1S/Mg" ; chebi:inchikey "FYYHWMGAXLPEAU-UHFFFAOYSA-N" ; chebi:mass "24.30500" ; chebi:monoisotopicmass "23.98504" ; chebi:smiles "[Mg]" ; oboInOwl:hasDbXref "CAS:7439-95-4", "DrugBank:DB01378", "Gmelin:16207", "KEGG:C00305", "WebElements:Mg" ; oboInOwl:hasExactSynonym "magnesium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "12Mg", "Magnesium", "Mg", "magnesio", "magnesium" ; oboInOwl:id "CHEBI:25107" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "magnesium atom" ; rdfs:subClassOf obo:CHEBI_22313, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_25195 chebi:charge "0" ; chebi:formula "Hg" ; chebi:inchi "InChI=1S/Hg" ; chebi:inchikey "QSHDDOUJBYECFT-UHFFFAOYSA-N" ; chebi:mass "200.59000" ; chebi:monoisotopicmass "201.97064" ; chebi:smiles "[Hg]" ; oboInOwl:hasDbXref "CAS:7439-97-6", "WebElements:Hg" ; oboInOwl:hasExactSynonym "mercury" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "80Hg", "Hg", "Quecksilber", "azogue", "hydrargyrum", "liquid silver", "mercure", "mercurio", "mercury", "quicksilver" ; oboInOwl:id "CHEBI:25195" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mercury atom" ; rdfs:subClassOf obo:CHEBI_33340 . obo:CHEBI_25212 obo:IAO_0000115 "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." ; oboInOwl:hasAlternativeId "CHEBI:26619", "CHEBI:35220" ; oboInOwl:hasExactSynonym "metabolite" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metabolites", "primary metabolites", "secondary metabolites" ; oboInOwl:id "CHEBI:25212" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "metabolite" ; rdfs:subClassOf obo:CHEBI_52206 . obo:CHEBI_25213 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a metal cation", "metal cations" ; oboInOwl:id "CHEBI:25213" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "metal cation" ; rdfs:subClassOf obo:CHEBI_23906, obo:CHEBI_36915 . obo:CHEBI_25216 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metalloporphyrins", "metaloporphyrins" ; oboInOwl:id "CHEBI:25216" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "metalloporphyrin" ; rdfs:subClassOf obo:CHEBI_26214, obo:CHEBI_33240, obo:CHEBI_33909 . obo:CHEBI_25223 obo:IAO_0000115 "An organosulfonic ester resulting from the formal condensation of methanesulfonic acid with the hydroxy group of an alcohol, phenol, heteroarenol, or enol." ; chebi:charge "0" ; chebi:formula "CH3O3SR" ; chebi:mass "95.099" ; chebi:monoisotopicmass "94.98029" ; chebi:smiles "CS(O*)(=O)=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mesylate ester", "mesylate esters", "methanesulfonic acid esters" ; oboInOwl:id "CHEBI:25223" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methanesulfonate ester" ; rdfs:subClassOf obo:CHEBI_48544, obo:CHEBI_83347 . obo:CHEBI_25224 obo:IAO_0000115 "A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid." ; chebi:charge "-1" ; chebi:formula "CH3O3S" ; chebi:inchi "InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)/p-1" ; chebi:inchikey "AFVFQIVMOAPDHO-UHFFFAOYSA-M" ; chebi:mass "95.09872" ; chebi:monoisotopicmass "94.98084" ; chebi:smiles "CS([O-])(=O)=O" ; oboInOwl:hasDbXref "MetaCyc:CPD-3746", "UM-BBD_compID:c0347" ; oboInOwl:hasExactSynonym "methanesulfonate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methylsulfonate" ; oboInOwl:id "CHEBI:25224" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methanesulfonate" ; rdfs:subClassOf obo:CHEBI_62081, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_27376 ] . obo:CHEBI_25248 obo:IAO_0000115 "Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol." ; chebi:charge "0" ; chebi:formula "C2H3O2R" ; chebi:mass "59.044" ; chebi:monoisotopicmass "59.01330" ; chebi:smiles "COC([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carboxylic acid methyl ester", "carboxylic acid methyl esters" ; oboInOwl:id "CHEBI:25248" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methyl ester" ; rdfs:subClassOf obo:CHEBI_33308, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17790 ] . obo:CHEBI_25255 obo:IAO_0000115 "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol." ; chebi:charge "0" ; chebi:formula "C2H6O3S" ; chebi:inchi "InChI=1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3" ; chebi:inchikey "MBABOKRGFJTBAE-UHFFFAOYSA-N" ; chebi:mass "110.13200" ; chebi:monoisotopicmass "110.00377" ; chebi:smiles "COS(C)(=O)=O" ; oboInOwl:hasDbXref "CAS:66-27-3", "KEGG:C19181", "MetaCyc:CPD-7038", "PMID:11016630", "PMID:14761437", "PMID:16764919", "PMID:21353429", "PMID:21860482", "PMID:22907509", "PMID:23117069", "PMID:23384783", "PMID:23483329", "Reaxys:1098586", "Wikipedia:Methyl_methanesulfonate" ; oboInOwl:hasExactSynonym "methyl methanesulfonate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CB1540", "MMS", "Methanesulfonic acid methyl ester", "Methyl mesylate", "as-Dimethyl sulfite" ; oboInOwl:id "CHEBI:25255" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methyl methanesulfonate" ; rdfs:subClassOf obo:CHEBI_25223, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22333 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50903 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_68495 ] . obo:CHEBI_25348 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methylxanthines" ; oboInOwl:id "CHEBI:25348" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methylxanthine" ; rdfs:subClassOf obo:CHEBI_26385, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_15318 ] . obo:CHEBI_25362 obo:IAO_0000115 "A molecule all atoms of which have the same atomic number." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "homoatomic molecule", "homoatomic molecules" ; oboInOwl:id "CHEBI:25362" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental molecule" ; rdfs:subClassOf obo:CHEBI_25367, obo:CHEBI_33259 . obo:CHEBI_25367 obo:IAO_0000115 "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." ; oboInOwl:hasExactSynonym "molecule" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Molekuel", "molecula", "molecules", "neutral molecular compounds" ; oboInOwl:id "CHEBI:25367" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "molecule" ; rdfs:subClassOf obo:CHEBI_36357 . obo:CHEBI_25375 obo:IAO_0000115 "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monamines", "monoamines" ; oboInOwl:id "CHEBI:25375" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoamine molecular messenger" ; rdfs:subClassOf obo:CHEBI_63534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33280 ] . obo:CHEBI_25384 obo:IAO_0000115 "An oxoacid containing a single carboxy group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monocarboxylic acids" ; oboInOwl:id "CHEBI:25384" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monocarboxylic acid" ; rdfs:subClassOf obo:CHEBI_33575, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_35757 ] . obo:CHEBI_25413 obo:IAO_0000115 "Any fatty acid with one double or triple bond in the fatty acid chain and singly bonded carbon atoms in the rest of the chain. MUFAs have positive effects on the cardiovascular system, and in diabetes treatment." ; oboInOwl:hasDbXref "PMID:10584045", "PMID:12936956" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "MUFA", "MUFAs", "monounsaturated fatty acids" ; oboInOwl:id "CHEBI:25413" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monounsaturated fatty acid" ; rdfs:subClassOf obo:CHEBI_27208, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_82680 ] . obo:CHEBI_25414 chebi:charge "+1" ; chebi:mass "0.00000" ; chebi:smiles "[*+]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic monocations", "monovalent inorganic cations" ; oboInOwl:id "CHEBI:25414" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic monocation" ; rdfs:subClassOf obo:CHEBI_23906 . obo:CHEBI_25435 obo:IAO_0000115 "An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution." ; oboInOwl:hasDbXref "Wikipedia:Mutagen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mutagene", "mutagenes", "mutagenic agent", "mutageno", "mutagenos", "mutagens" ; oboInOwl:id "CHEBI:25435" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mutagen" ; rdfs:subClassOf obo:CHEBI_50902 . obo:CHEBI_25442 obo:IAO_0000115 "Poisonous substance produced by fungi." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fungal toxins", "mycotoxins" ; oboInOwl:id "CHEBI:25442" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mycotoxin" ; rdfs:subClassOf obo:CHEBI_27026, obo:CHEBI_76946 . obo:CHEBI_25491 obo:IAO_0000115 "A substance used to destroy pests of the phylum Nematoda (roundworms)." ; oboInOwl:hasDbXref "Wikipedia:Nematicide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nematicides", "nematocide", "nematocides" ; oboInOwl:id "CHEBI:25491" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nematicide" ; rdfs:subClassOf obo:CHEBI_25944 . obo:CHEBI_25512 obo:IAO_0000115 "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." ; oboInOwl:hasDbXref "Wikipedia:Neurotransmitter" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "neurotransmitters" ; oboInOwl:id "CHEBI:25512" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "neurotransmitter" ; rdfs:subClassOf obo:CHEBI_33280 . obo:CHEBI_2555 obo:IAO_0000115 "The oxime carbamate resulting from the addition of 2-methyl-2-(methylsulfanyl)propanaldoxime to methyl isocyanate. A member of the class of oxime carbamate insecticides, aldicarb is a mixture of E and Z isomers; it is not known which isomer is more active." ; chebi:charge "0" ; chebi:formula "C7H14N2O2S" ; chebi:inchi "InChI=1S/C7H14N2O2S/c1-7(2,12-4)5-9-11-6(10)8-3/h5H,1-4H3,(H,8,10)" ; chebi:inchikey "QGLZXHRNAYXIBU-UHFFFAOYSA-N" ; chebi:mass "190.26300" ; chebi:monoisotopicmass "190.07760" ; chebi:smiles "[H]C(=NOC(=O)NC)C(C)(C)SC" ; oboInOwl:hasDbXref "Beilstein:2046931", "CAS:116-06-3", "KEGG:C11015", "LINCS:LSM-20978", "PPDB:19", "Patent:US3217037" ; oboInOwl:hasExactSynonym "2-methyl-N-[(methylcarbamoyl)oxy]-2-(methylsulfanyl)propan-1-imine", "Aldicarb", "aldicarb" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-Methyl-2-(methylthio)propanal, O-((methylamino)carbonyl)oxime", "2-Methyl-2-(methylthio)propionaldehyde O-(methylcarbamoyl)oxime", "2-Methyl-2-methylthio-propionaldehyd-O-(N-methyl-carbamoyl)-oxim", "aldicarbe" ; oboInOwl:id "CHEBI:2555" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aldicarb" ; rdfs:subClassOf obo:CHEBI_23003, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22153 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25491 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38461 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_59059 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_60330 ] . obo:CHEBI_25555 chebi:charge "0" ; chebi:formula "N" ; chebi:mass "14.007" ; chebi:monoisotopicmass "14.00307" ; oboInOwl:hasDbXref "WebElements:N" ; oboInOwl:hasExactSynonym "nitrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "7N", "N", "Stickstoff", "azote", "nitrogen", "nitrogeno" ; oboInOwl:id "CHEBI:25555" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nitrogen atom" ; rdfs:subClassOf obo:CHEBI_25585, obo:CHEBI_33300, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_25579 obo:IAO_0000115 "Any ketone that is nonane substituted by an oxo group at unspecified position." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nonanones" ; oboInOwl:id "CHEBI:25579" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nonanone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_25585 oboInOwl:hasExactSynonym "nonmetal" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Nichtmetall", "Nichtmetalle", "no metal", "no metales", "non-metal", "non-metaux", "nonmetal", "nonmetals" ; oboInOwl:id "CHEBI:25585" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nonmetal atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_25608 obo:IAO_0000115 "A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates." ; oboInOwl:hasDbXref "KEGG:C01329" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NMP", "Nucleoside monophosphate", "nucleoside phosphates" ; oboInOwl:id "CHEBI:25608" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside phosphate" ; rdfs:subClassOf obo:CHEBI_25703, obo:CHEBI_37734, obo:CHEBI_61120, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33838 ] . obo:CHEBI_25676 obo:IAO_0000115 "A peptide containing a relatively small number of amino acids." ; oboInOwl:hasAlternativeId "CHEBI:7755" ; oboInOwl:hasDbXref "Wikipedia:Oligopeptide" ; oboInOwl:hasExactSynonym "oligopeptides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Oligopeptid", "oligopeptido" ; oboInOwl:id "CHEBI:25676" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oligopeptide" ; rdfs:subClassOf obo:CHEBI_16670 . obo:CHEBI_25693 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic heteromonocyclic compounds" ; oboInOwl:id "CHEBI:25693" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic heteromonocyclic compound" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_33670 . obo:CHEBI_25696 obo:IAO_0000115 "Any organic ion with a net negative charge." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic anions" ; oboInOwl:id "CHEBI:25696" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic anion" ; rdfs:subClassOf obo:CHEBI_22563, obo:CHEBI_25699 . obo:CHEBI_25697 obo:IAO_0000115 "Any organic ion with a net positive charge." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic cations" ; oboInOwl:id "CHEBI:25697" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic cation" ; rdfs:subClassOf obo:CHEBI_25699, obo:CHEBI_36916 . obo:CHEBI_25698 obo:IAO_0000115 "An organooxygen compound with formula ROR, where R is not hydrogen." ; chebi:charge "0" ; chebi:formula "OR2" ; chebi:mass "15.99940" ; chebi:monoisotopicmass "15.99491" ; chebi:smiles "[*]O[*]" ; oboInOwl:hasExactSynonym "ether", "ethers" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ethers" ; oboInOwl:id "CHEBI:25698" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ether" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_25699 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic ions" ; oboInOwl:id "CHEBI:25699" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic ion" ; rdfs:subClassOf obo:CHEBI_24870, obo:CHEBI_50860 . obo:CHEBI_25701 obo:IAO_0000115 "An oxide in which the oxygen atom is bonded to a carbon atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic oxides" ; oboInOwl:id "CHEBI:25701" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic oxide" ; rdfs:subClassOf obo:CHEBI_25741, obo:CHEBI_72695 . obo:CHEBI_25703 oboInOwl:hasDbXref "Wikipedia:Organophosphate" ; oboInOwl:hasExactSynonym "organic phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic phosphate ester", "organic phosphate esters", "organic phosphates", "organophosphate ester", "organophosphate esters" ; oboInOwl:id "CHEBI:25703" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic phosphate" ; rdfs:subClassOf obo:CHEBI_25710, obo:CHEBI_26020 . obo:CHEBI_25704 obo:IAO_0000115 "Compounds of the general formula SO3HOR where R is an organyl group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic sulfates" ; oboInOwl:id "CHEBI:25704" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic sulfate" ; rdfs:subClassOf obo:CHEBI_26820, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58958 ] . obo:CHEBI_2571 obo:IAO_0000115 "An alcohol derived from an aliphatic compound." ; chebi:charge "0" ; chebi:formula "HOR" ; chebi:mass "17.007" ; chebi:monoisotopicmass "17.00274" ; chebi:smiles "O*" ; oboInOwl:hasDbXref "KEGG:C02525" ; oboInOwl:hasExactSynonym "Aliphatic alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aliphatic alcohols", "an aliphatic alcohol" ; oboInOwl:id "CHEBI:2571" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aliphatic alcohol" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_25710 obo:IAO_0000115 "An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters." ; oboInOwl:hasDbXref "Wikipedia:Organophosphorus_compound" ; oboInOwl:hasExactSynonym "organophosphorus compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organophosphorus compounds" ; oboInOwl:id "CHEBI:25710" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organophosphorus compound" ; rdfs:subClassOf obo:CHEBI_26082, obo:CHEBI_33285 . obo:CHEBI_25728 obo:IAO_0000115 "A solute used by a cell under water stress to maintain cell volume." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "osmolytes" ; oboInOwl:id "CHEBI:25728" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "osmolyte" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_25741 obo:IAO_0000115 "An oxide is a chemical compound of oxygen with other chemical elements." ; oboInOwl:hasExactSynonym "oxide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxides" ; oboInOwl:id "CHEBI:25741" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxide" ; rdfs:subClassOf obo:CHEBI_25806, obo:CHEBI_37577 . obo:CHEBI_25750 obo:IAO_0000115 "Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes." ; chebi:charge "0" ; chebi:formula "CHNOR2" ; chebi:mass "43.02470" ; chebi:monoisotopicmass "43.00581" ; chebi:smiles "O\\N=C(\\[*])[*]" ; oboInOwl:hasExactSynonym "oxime", "oximes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oximes" ; oboInOwl:id "CHEBI:25750" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxime" ; rdfs:subClassOf obo:CHEBI_50860, obo:CHEBI_51143, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_142513 ] . obo:CHEBI_2580 obo:IAO_0000115 "Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:2580" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "unsaturated fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_27208 ] . obo:CHEBI_25805 chebi:charge "0" ; chebi:formula "O" ; chebi:inchi "InChI=1S/O" ; chebi:inchikey "QVGXLLKOCUKJST-UHFFFAOYSA-N" ; chebi:mass "15.99940" ; chebi:monoisotopicmass "15.99491" ; chebi:smiles "[O]" ; oboInOwl:hasDbXref "KEGG:C00007", "WebElements:O" ; oboInOwl:hasExactSynonym "oxygen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "8O", "O", "Sauerstoff", "oxigeno", "oxygen", "oxygene" ; oboInOwl:id "CHEBI:25805" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxygen atom" ; rdfs:subClassOf obo:CHEBI_25585, obo:CHEBI_33303, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_25806 oboInOwl:hasExactSynonym "oxygen molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxygen molecular entities" ; oboInOwl:id "CHEBI:25806" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxygen molecular entity" ; rdfs:subClassOf obo:CHEBI_33304, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_25805 ] . obo:CHEBI_25810 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxopurines" ; oboInOwl:id "CHEBI:25810" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxopurine" ; rdfs:subClassOf obo:CHEBI_26401 . obo:CHEBI_25897 obo:IAO_0000115 "Any C5, straight-chain, monounsaturated fatty acid." ; chebi:charge "0" ; chebi:formula "C5H8O2" ; chebi:mass "100.116" ; chebi:monoisotopicmass "100.05243" ; oboInOwl:hasExactSynonym "pentenoic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C5:1", "pentenoic acids" ; oboInOwl:id "CHEBI:25897" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pentenoic acid" ; rdfs:subClassOf obo:CHEBI_25413, obo:CHEBI_26666, obo:CHEBI_59202 . obo:CHEBI_25900 oboInOwl:hasExactSynonym "aldopentose phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldopentose phosphates" ; oboInOwl:id "CHEBI:25900" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aldopentose phosphate" ; rdfs:subClassOf obo:CHEBI_35131, obo:CHEBI_84055 . obo:CHEBI_25901 obo:IAO_0000115 "A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose)." ; oboInOwl:hasExactSynonym "pentose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pentoses" ; oboInOwl:id "CHEBI:25901" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pentose" ; rdfs:subClassOf obo:CHEBI_35381 . obo:CHEBI_25905 obo:IAO_0000115 "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "peptide hormones", "polypeptide hormone" ; oboInOwl:id "CHEBI:25905" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "peptide hormone" ; rdfs:subClassOf obo:CHEBI_16670, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24621 ] . obo:CHEBI_25940 obo:IAO_0000115 "Compounds of structure ROOR'." ; chebi:charge "0" ; chebi:formula "O2R2" ; chebi:mass "31.999" ; chebi:monoisotopicmass "31.98983" ; chebi:smiles "[*]OO[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a peroxide" ; oboInOwl:id "CHEBI:25940" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "peroxides" ; rdfs:subClassOf obo:CHEBI_25741, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29369 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63248 ] . obo:CHEBI_25944 obo:IAO_0000115 "Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests." ; oboInOwl:hasDbXref "Wikipedia:Pesticide" ; oboInOwl:hasExactSynonym "pesticide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Pestizid", "Pestizide", "pesticides" ; oboInOwl:id "CHEBI:25944" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pesticide" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_25990 obo:IAO_0000115 "An ethanolamine compound having a phenyl (substituted or unsubstituted) group on the carbon bearing the hydroxy substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:25990" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phenylethanolamines" ; rdfs:subClassOf obo:CHEBI_23981 . obo:CHEBI_26020 obo:IAO_0000115 "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." ; oboInOwl:hasExactSynonym "phosphates" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "phosphates" ; oboInOwl:id "CHEBI:26020" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphate" ; rdfs:subClassOf obo:CHEBI_26079 . obo:CHEBI_26034 obo:IAO_0000115 "A phosphatidylinositol monophosphate carrying the phosphate group at the 3-position." ; oboInOwl:hasDbXref "PMID:18927492" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "PI(3)P", "PtdIns3P", "phosphatidylinositol 3-phosphates" ; oboInOwl:id "CHEBI:26034" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphatidylinositol 3-phosphate" ; rdfs:subClassOf obo:CHEBI_26036 . obo:CHEBI_26036 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "phosphatidylinositol monophosphates" ; oboInOwl:id "CHEBI:26036" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphatidylinositol monophosphate" ; rdfs:subClassOf obo:CHEBI_28765 . obo:CHEBI_26078 obo:IAO_0000115 "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." ; chebi:charge "0" ; chebi:formula "H3O4P" ; chebi:inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)" ; chebi:inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-N" ; chebi:mass "97.99520" ; chebi:monoisotopicmass "97.97690" ; chebi:smiles "[H]OP(=O)(O[H])O[H]" ; oboInOwl:hasDbXref "Beilstein:1921286", "CAS:7664-38-2", "Drug_Central:4478", "Gmelin:2000", "HMDB:HMDB0002142", "KEGG:C00009", "KEGG:D05467", "KNApSAcK:C00007408", "PMID:11455380", "PMID:15630224", "PMID:17439666", "PMID:17518491", "PMID:22282755", "PMID:22333268", "PMID:22381614", "PMID:22401268", "Reaxys:1921286", "Wikipedia:Phosphoric_Acid" ; oboInOwl:hasExactSynonym "Phosphoric acid", "phosphoric acid", "tetraoxophosphoric acid", "trihydrogen tetraoxophosphate(3-)", "trihydroxidooxidophosphorus" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H3PO4", "Orthophosphoric acid", "Phosphate", "Phosphorsaeure", "Phosphorsaeureloesungen", "[PO(OH)3]", "acide phosphorique", "acidum phosphoricum", "orthophosphoric acid" ; oboInOwl:id "CHEBI:26078" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphoric acid" ; rdfs:subClassOf obo:CHEBI_59698, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33287 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84735 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_39745 ] . obo:CHEBI_26079 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26079" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "phosphoric acid derivative" ; rdfs:subClassOf obo:CHEBI_36359, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_26078 ] . obo:CHEBI_26082 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "phosphorus molecular entities" ; oboInOwl:id "CHEBI:26082" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphorus molecular entity" ; rdfs:subClassOf obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_28659 ] . obo:CHEBI_26144 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26144" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "piperazines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_26151 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26151" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "piperidines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_26167 obo:IAO_0000115 "Any amino acid whose side chain is capable of forming one or more hydrogen bonds." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "OC(C(*)N)=O" ; oboInOwl:hasAlternativeId "CHEBI:8283" ; oboInOwl:hasDbXref "MetaCyc:Polar-amino-acids", "PMID:12016058" ; oboInOwl:hasExactSynonym "polar amino acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polar amino acids", "polar amino-acid", "polar amino-acids" ; oboInOwl:id "CHEBI:26167" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polar amino acid" ; rdfs:subClassOf obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_62031 ] . obo:CHEBI_26188 obo:IAO_0000115 "Natural and synthetic compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides." ; oboInOwl:hasExactSynonym "polyketide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyketides" ; oboInOwl:id "CHEBI:26188" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polyketide" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_26191 obo:IAO_0000115 "A compound that contains two or more hydroxy groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyols" ; oboInOwl:id "CHEBI:26191" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polyol" ; rdfs:subClassOf obo:CHEBI_33822 . obo:CHEBI_26214 obo:IAO_0000115 "Natural pigments containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure." ; oboInOwl:hasDbXref "Wikipedia:Porphyrin" ; oboInOwl:hasExactSynonym "porphyrins" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26214" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "porphyrins" ; rdfs:subClassOf obo:CHEBI_36309, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ] . obo:CHEBI_26216 chebi:charge "0" ; chebi:formula "K" ; chebi:inchi "InChI=1S/K" ; chebi:inchikey "ZLMJMSJWJFRBEC-UHFFFAOYSA-N" ; chebi:mass "39.09830" ; chebi:monoisotopicmass "38.96371" ; chebi:smiles "[K]" ; oboInOwl:hasDbXref "CAS:7440-09-7", "DrugBank:DB01345", "KEGG:C00238", "WebElements:K" ; oboInOwl:hasExactSynonym "potassium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "19K", "K", "Kalium", "kalium", "potasio", "potassium" ; oboInOwl:id "CHEBI:26216" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "potassium atom" ; rdfs:subClassOf obo:CHEBI_22314, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ] . obo:CHEBI_26292 obo:IAO_0000115 "A ketone that is propane carrying at least one oxo substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26292" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "propanones" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_26348 obo:IAO_0000115 "A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity." ; oboInOwl:hasExactSynonym "prosthetic group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "groupe prosthetique", "prosthetic groups" ; oboInOwl:id "CHEBI:26348" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "prosthetic group" ; rdfs:subClassOf obo:CHEBI_23357 . obo:CHEBI_26385 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine alkaloids" ; oboInOwl:id "CHEBI:26385" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine alkaloid" ; rdfs:subClassOf obo:CHEBI_22315, obo:CHEBI_26401 . obo:CHEBI_26386 obo:IAO_0000115 "A nucleobase whose skeleton is derived from purine." ; chebi:charge "0" ; chebi:formula "C5H3N4R2" ; chebi:mass "119.104" ; chebi:monoisotopicmass "119.03577" ; chebi:smiles "C1(NC(=NC=2NC=NC12)*)=*" ; oboInOwl:hasDbXref "KEGG:C15587" ; oboInOwl:hasExactSynonym "purine nucleobase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a purine nucleobase", "purine bases", "purine nucleobases" ; oboInOwl:id "CHEBI:26386" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine nucleobase" ; rdfs:subClassOf obo:CHEBI_18282, obo:CHEBI_26401 . obo:CHEBI_26393 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine nucleoside triphosphates" ; oboInOwl:id "CHEBI:26393" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine nucleoside triphosphate" ; rdfs:subClassOf obo:CHEBI_17326 . obo:CHEBI_26394 oboInOwl:hasExactSynonym "purine nucleoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine nucleosides" ; oboInOwl:id "CHEBI:26394" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine nucleoside" ; rdfs:subClassOf obo:CHEBI_26401, obo:CHEBI_33838 . obo:CHEBI_26395 obo:IAO_0000115 "Any nucleotide that has a purine nucleobase." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine nucleotides" ; oboInOwl:id "CHEBI:26395" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine nucleotide" ; rdfs:subClassOf obo:CHEBI_26401, obo:CHEBI_36976 . obo:CHEBI_26398 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine ribonucleoside triphosphates" ; oboInOwl:id "CHEBI:26398" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine ribonucleoside triphosphate" ; rdfs:subClassOf obo:CHEBI_17972, obo:CHEBI_26393 . obo:CHEBI_26399 obo:IAO_0000115 "A ribonucleoside that has a purine moiety as the nucleobase (the R group in the illustration)." ; chebi:charge "0" ; chebi:formula "C5H9O4R" ; chebi:mass "133.123" ; chebi:monoisotopicmass "133.05008" ; chebi:smiles "*[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine ribonucleosides" ; oboInOwl:id "CHEBI:26399" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine ribonucleoside" ; rdfs:subClassOf obo:CHEBI_18254, obo:CHEBI_26394 . obo:CHEBI_26400 obo:IAO_0000115 "Any ribonucleotide that has a purine nucleobase." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine ribonucleotides" ; oboInOwl:id "CHEBI:26400" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine ribonucleotide" ; rdfs:subClassOf obo:CHEBI_26395, obo:CHEBI_26561 . obo:CHEBI_26401 obo:IAO_0000115 "A class of imidazopyrimidines that consists of purine and its substituted derivatives." ; chebi:charge "0" ; chebi:formula "C5N4R7" ; chebi:mass "116.080" ; chebi:monoisotopicmass "116.01230" ; oboInOwl:hasAlternativeId "CHEBI:13678" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26401" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purines" ; rdfs:subClassOf obo:CHEBI_35875 . obo:CHEBI_26416 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyridine alkaloids" ; oboInOwl:id "CHEBI:26416" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyridine alkaloid" ; rdfs:subClassOf obo:CHEBI_22315, obo:CHEBI_26421 . obo:CHEBI_26421 obo:IAO_0000115 "Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26421" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyridines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_26432 obo:IAO_0000115 "A nucleobase whose skeleton is derived from pyrimidine." ; chebi:charge "0" ; chebi:formula "C4HN2R4" ; chebi:mass "77.064" ; chebi:monoisotopicmass "77.01397" ; chebi:smiles "N1C(=C(C(=NC1=*)*)*)*" ; oboInOwl:hasExactSynonym "pyrimidine nucleobase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a pyrimidine nucleobase", "pyrimidine bases", "pyrimidine nucleobases" ; oboInOwl:id "CHEBI:26432" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyrimidine nucleobase" ; rdfs:subClassOf obo:CHEBI_18282, obo:CHEBI_39447 . obo:CHEBI_26456 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyrrolidine alkaloids" ; oboInOwl:id "CHEBI:26456" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyrrolidine alkaloid" ; rdfs:subClassOf obo:CHEBI_22315, obo:CHEBI_38260 . obo:CHEBI_26469 obo:IAO_0000115 "A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26469" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "quaternary nitrogen compound" ; rdfs:subClassOf obo:CHEBI_35352, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_35267 ] . obo:CHEBI_26509 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "quinoline alkaloids" ; oboInOwl:id "CHEBI:26509" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "quinoline alkaloid" ; rdfs:subClassOf obo:CHEBI_22315 . obo:CHEBI_26513 obo:IAO_0000115 "A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26513" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "quinolines" ; rdfs:subClassOf obo:CHEBI_33659, obo:CHEBI_38101 . obo:CHEBI_26523 obo:IAO_0000115 "Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." ; oboInOwl:hasDbXref "Wikipedia:Reactive_oxygen_species" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ROS" ; oboInOwl:id "CHEBI:26523" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "reactive oxygen species" ; rdfs:subClassOf obo:CHEBI_25806 . obo:CHEBI_26547 oboInOwl:hasExactSynonym "rhamnoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "rhamnosides" ; oboInOwl:id "CHEBI:26547" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "rhamnoside" ; rdfs:subClassOf obo:CHEBI_35315 . obo:CHEBI_26561 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleotides" ; oboInOwl:id "CHEBI:26561" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribonucleotide" ; rdfs:subClassOf obo:CHEBI_26562, obo:CHEBI_36976 . obo:CHEBI_26562 oboInOwl:hasExactSynonym "ribose phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribose phosphates" ; oboInOwl:id "CHEBI:26562" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribose phosphate" ; rdfs:subClassOf obo:CHEBI_25900 . obo:CHEBI_26607 obo:IAO_0000115 "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess." ; oboInOwl:hasDbXref "PMID:16492686", "PMID:19763019", "PMID:20237329" ; oboInOwl:hasExactSynonym "saturated fatty acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SFA", "SFAs", "saturated fatty acids" ; oboInOwl:id "CHEBI:26607" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "saturated fatty acid" ; rdfs:subClassOf obo:CHEBI_35366 . obo:CHEBI_26650 obo:IAO_0000115 "An L-alpha-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class." ; oboInOwl:hasDbXref "PMID:20709681" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3-phosphoglycerate family amino acid", "3-phosphoglycerate family amino acids", "serine family amino acids" ; oboInOwl:id "CHEBI:26650" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "serine family amino acid" ; rdfs:subClassOf obo:CHEBI_15705, obo:CHEBI_83813 . obo:CHEBI_26666 obo:IAO_0000115 "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." ; chebi:charge "0" ; chebi:formula "CH2OR" ; chebi:mass "45.017" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "OC([*])=O" ; oboInOwl:hasDbXref "PMID:16633129", "PMID:16870803", "PMID:18203540", "PMID:20148677" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SCFA", "SCFAs", "short-chain fatty acids" ; oboInOwl:id "CHEBI:26666" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "short-chain fatty acid" ; rdfs:subClassOf obo:CHEBI_35366, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58951 ] . obo:CHEBI_26708 chebi:charge "0" ; chebi:formula "Na" ; chebi:inchi "InChI=1S/Na" ; chebi:inchikey "KEAYESYHFKHZAL-UHFFFAOYSA-N" ; chebi:mass "22.98977" ; chebi:monoisotopicmass "22.98977" ; chebi:smiles "[Na]" ; oboInOwl:hasDbXref "CAS:7440-23-5", "Gmelin:16221", "KEGG:C01330", "WebElements:Na" ; oboInOwl:hasExactSynonym "sodium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "11Na", "Na", "Natrium", "natrium", "sodio", "sodium" ; oboInOwl:id "CHEBI:26708" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sodium atom" ; rdfs:subClassOf obo:CHEBI_22314, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ] . obo:CHEBI_26710 obo:IAO_0000115 "An inorganic chloride salt having sodium(1+) as the counterion." ; chebi:charge "0" ; chebi:formula "ClNa" ; chebi:inchi "InChI=1S/ClH.Na/h1H;/q;+1/p-1" ; chebi:inchikey "FAPWRFPIFSIZLT-UHFFFAOYSA-M" ; chebi:mass "58.44247" ; chebi:monoisotopicmass "57.95862" ; chebi:smiles "[Na+].[Cl-]" ; oboInOwl:hasDbXref "Beilstein:3534976", "CAS:7647-14-5", "Gmelin:13673", "KEGG:C13563", "KEGG:D02056", "MetaCyc:NACL", "PPDB:595", "Reaxys:3534976", "Wikipedia:Sodium_Chloride" ; oboInOwl:hasExactSynonym "sodium chloride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kochsalz", "NaCl", "Natriumchlorid", "chlorure de sodium", "cloruro sodico", "common salt", "halite", "natrii chloridum", "rock salt", "salt", "table salt" ; oboInOwl:id "CHEBI:26710" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sodium chloride" ; rdfs:subClassOf obo:CHEBI_36093, obo:CHEBI_38702, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149552 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_79314 ] . obo:CHEBI_26712 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sodium compounds", "sodium molecular entities" ; oboInOwl:id "CHEBI:26712" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sodium molecular entity" ; rdfs:subClassOf obo:CHEBI_33296, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_26708 ] . obo:CHEBI_26714 obo:IAO_0000115 "Any alkali metal salt having sodium(1+) as the cation." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Natriumsalz", "Natriumsalze", "sodium salts" ; oboInOwl:id "CHEBI:26714" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sodium salt" ; rdfs:subClassOf obo:CHEBI_26712, obo:CHEBI_35479, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29101 ] . obo:CHEBI_26764 obo:IAO_0000115 "Any steroid that acts as hormone." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Steroidhormon", "Steroidhormone", "hormona esteroide", "hormonas esteroideas", "hormone steroide", "hormones steroides", "steroid hormones" ; oboInOwl:id "CHEBI:26764" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "steroid hormone" ; rdfs:subClassOf obo:CHEBI_35341, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24621 ] . obo:CHEBI_26766 oboInOwl:hasDbXref "KEGG:C15507" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "steroid lactones" ; oboInOwl:id "CHEBI:26766" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "steroid lactone" ; rdfs:subClassOf obo:CHEBI_25000, obo:CHEBI_35341 . obo:CHEBI_26816 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrate phosphates" ; oboInOwl:id "CHEBI:26816" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbohydrate phosphate" ; rdfs:subClassOf obo:CHEBI_25703, obo:CHEBI_37734, obo:CHEBI_63299 . obo:CHEBI_26819 obo:IAO_0000115 "An ester of an alcohol and sulfuric acid." ; chebi:charge "0" ; chebi:formula "O4SR2" ; chebi:mass "96.06300" ; chebi:monoisotopicmass "95.95173" ; chebi:smiles "[*]OS(=O)(=O)O[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfate ester", "sulfuric acid ester", "sulfuric acid esters" ; oboInOwl:id "CHEBI:26819" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfuric ester" ; rdfs:subClassOf obo:CHEBI_35701, obo:CHEBI_37826 . obo:CHEBI_26820 obo:IAO_0000115 "Salts and esters of sulfuric acid" ; oboInOwl:hasExactSynonym "sulfates" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfuric acid derivative", "sulphates" ; oboInOwl:id "CHEBI:26820" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfates" ; rdfs:subClassOf obo:CHEBI_37826 . obo:CHEBI_26822 obo:IAO_0000115 "Any sulfur molecular entity that involves either covalently bonded or anionic sulfur." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulphides" ; oboInOwl:id "CHEBI:26822" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfide" ; rdfs:subClassOf obo:CHEBI_26835 . obo:CHEBI_26830 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26830" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "sulfonium compound" ; rdfs:subClassOf obo:CHEBI_26835 . obo:CHEBI_26833 chebi:charge "0" ; chebi:formula "S" ; chebi:inchi "InChI=1S/S" ; chebi:inchikey "NINIDFKCEFEMDL-UHFFFAOYSA-N" ; chebi:mass "32.06600" ; chebi:monoisotopicmass "31.97207" ; chebi:smiles "[S]" ; oboInOwl:hasDbXref "CAS:7704-34-9", "KEGG:C00087", "KEGG:D06527", "PPDB:605", "WebElements:S" ; oboInOwl:hasExactSynonym "sulfur" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "16S", "Elemental sulfur", "S", "Schwefel", "azufre", "soufre", "sulfur", "sulphur", "theion" ; oboInOwl:id "CHEBI:26833" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur atom" ; rdfs:subClassOf obo:CHEBI_25585, obo:CHEBI_33303, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_26834 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfur-containing amino acids" ; oboInOwl:id "CHEBI:26834" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur-containing amino acid" ; rdfs:subClassOf obo:CHEBI_33576, obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_63470 ] . obo:CHEBI_26835 oboInOwl:hasExactSynonym "sulfur molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfur molecular entities" ; oboInOwl:id "CHEBI:26835" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur molecular entity" ; rdfs:subClassOf obo:CHEBI_33304, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_26833 ] . obo:CHEBI_26836 obo:IAO_0000115 "A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom." ; chebi:charge "0" ; chebi:formula "H2O4S" ; chebi:inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)" ; chebi:inchikey "QAOWNCQODCNURD-UHFFFAOYSA-N" ; chebi:mass "98.07948" ; chebi:monoisotopicmass "97.96738" ; chebi:smiles "[H]OS(=O)(=O)O[H]" ; oboInOwl:hasDbXref "CAS:7664-93-9", "Gmelin:2122", "KEGG:C00059", "KEGG:D05963", "KNApSAcK:C00007530", "MolBase:4", "PMID:13568755", "PMID:16122922", "PMID:19397353", "PMID:22047659", "PMID:22136045", "PMID:22204399", "PMID:22267186", "PMID:22296037", "PMID:22364556", "PMID:22435616", "PPDB:606", "Reaxys:2037554", "Wikipedia:Sulfuric_acid" ; oboInOwl:hasExactSynonym "Sulfuric acid", "dihydrogen tetraoxosulfate", "dihydroxidodioxidosulfur", "hydrogen tetraoxosulfate(2-)", "hydrogen tetraoxosulfate(VI)", "sulfuric acid", "tetraoxosulfuric acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Acide sulfurique", "Acido sulfurico", "Acidum sulfuricum", "H2SO4", "Schwefelsaeureloesungen", "[S(OH)2O2]", "[SO2(OH)2]", "sulphuric acid" ; oboInOwl:id "CHEBI:26836" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfuric acid" ; rdfs:subClassOf obo:CHEBI_33402, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35223 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_45696 ] . obo:CHEBI_26873 obo:IAO_0000115 "Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group." ; oboInOwl:hasDbXref "Wikipedia:Terpenoid" ; oboInOwl:hasExactSynonym "Terpenoid", "terpenoids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "terpenoide", "terpenoides" ; oboInOwl:id "CHEBI:26873" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "terpenoid" ; rdfs:subClassOf obo:CHEBI_24913, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_35186 ] . obo:CHEBI_26878 obo:IAO_0000115 "A tertiary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it." ; chebi:charge "0" ; chebi:formula "C4H7OR3" ; chebi:mass "71.09780" ; chebi:monoisotopicmass "71.04969" ; chebi:smiles "OC(C[*])(C[*])C[*]" ; oboInOwl:hasExactSynonym "tertiary alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tertiary alcohols" ; oboInOwl:id "CHEBI:26878" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tertiary alcohol" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_26912 obo:IAO_0000115 "Any oxacycle having an oxolane (tetrahydrofuran) skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26912" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxolanes" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38104 . obo:CHEBI_26921 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tetrahydropyridines" ; oboInOwl:id "CHEBI:26921" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tetrahydropyridine" ; rdfs:subClassOf obo:CHEBI_26421 . obo:CHEBI_26932 obo:IAO_0000115 "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." ; oboInOwl:hasExactSynonym "tetrapyrrole", "tetrapyrroles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a tetrapyrrole" ; oboInOwl:id "CHEBI:26932" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tetrapyrrole" ; rdfs:subClassOf obo:CHEBI_33833, obo:CHEBI_38077 . obo:CHEBI_26952 oboInOwl:hasDbXref "KEGG:C01857" ; oboInOwl:hasExactSynonym "ethanethioic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Thioessigsaeure" ; oboInOwl:id "CHEBI:26952" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "thioacetic acid" ; rdfs:subClassOf obo:CHEBI_35737, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30320 ] . obo:CHEBI_26959 obo:IAO_0000115 "An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "thiocarboxylic esters" ; oboInOwl:id "CHEBI:26959" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "thiocarboxylic ester" ; rdfs:subClassOf obo:CHEBI_33261, obo:CHEBI_35701 . obo:CHEBI_26979 obo:IAO_0000115 "An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterotricyclic compounds", "organic heterotricyclic compounds" ; oboInOwl:id "CHEBI:26979" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic heterotricyclic compound" ; rdfs:subClassOf obo:CHEBI_36688, obo:CHEBI_38166, obo:CHEBI_51959 . obo:CHEBI_27026 obo:IAO_0000115 "Poisonous substance produced by a biological organism such as a microbe, animal or plant." ; oboInOwl:hasDbXref "Wikipedia:Toxin" ; oboInOwl:hasExactSynonym "toxin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "toxins" ; oboInOwl:id "CHEBI:27026" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "toxin" ; rdfs:subClassOf obo:CHEBI_25212, obo:CHEBI_64909 . obo:CHEBI_27027 obo:IAO_0000115 "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." ; oboInOwl:hasDbXref "Wikipedia:Micronutrient" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "micronutrients", "trace elements" ; oboInOwl:id "CHEBI:27027" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "micronutrient" ; rdfs:subClassOf obo:CHEBI_33284 . obo:CHEBI_27081 obo:IAO_0000115 "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell." ; oboInOwl:hasExactSynonym "transition element" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Uebergangselement", "Uebergangsmetalle", "metal de transicion", "metal de transition", "metales de transicion", "metaux de transition", "transition element", "transition elements", "transition metal", "transition metals" ; oboInOwl:id "CHEBI:27081" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "transition element atom" ; rdfs:subClassOf obo:CHEBI_33521 . obo:CHEBI_27134 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "trimethylxanthines" ; oboInOwl:id "CHEBI:27134" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "trimethylxanthine" ; rdfs:subClassOf obo:CHEBI_25348 . obo:CHEBI_27136 obo:IAO_0000115 "A chemical compound containing three hydroxy groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "triols" ; oboInOwl:id "CHEBI:27136" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "triol" ; rdfs:subClassOf obo:CHEBI_26191 . obo:CHEBI_27162 obo:IAO_0000115 "Tryptamine and its substitution derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:27162" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tryptamines" ; rdfs:subClassOf obo:CHEBI_24828 . obo:CHEBI_27171 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterobicyclic compounds", "organic heterobicyclic compounds" ; oboInOwl:id "CHEBI:27171" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic heterobicyclic compound" ; rdfs:subClassOf obo:CHEBI_33672, obo:CHEBI_38166 . obo:CHEBI_27175 obo:IAO_0000115 "Aralkylamino compounds which contain a tyramine skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:27175" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tyramines" ; rdfs:subClassOf obo:CHEBI_33853, obo:CHEBI_64365 . obo:CHEBI_27207 obo:IAO_0000115 "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "univalent acyl group", "univalent carboacyl groups", "univalent carboxylic acyl groups" ; oboInOwl:id "CHEBI:27207" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "univalent carboacyl group" ; rdfs:subClassOf obo:CHEBI_37838 . obo:CHEBI_27208 obo:IAO_0000115 "Any fatty acid containing at least one C=C or C#C bond." ; oboInOwl:hasDbXref "LIPID_MAPS_class:LMFA0103", "PMID:5322381" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkene acid", "olefinic acid", "unsaturated fatty acids" ; oboInOwl:id "CHEBI:27208" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "unsaturated fatty acid" ; rdfs:subClassOf obo:CHEBI_35366, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_2580 ] . obo:CHEBI_27363 chebi:charge "0" ; chebi:formula "Zn" ; chebi:inchi "InChI=1S/Zn" ; chebi:inchikey "HCHKCACWOHOZIP-UHFFFAOYSA-N" ; chebi:mass "65.39000" ; chebi:monoisotopicmass "63.92914" ; chebi:smiles "[Zn]" ; oboInOwl:hasDbXref "CAS:7440-66-6", "Gmelin:16321", "KEGG:C00038", "PDBeChem:ZN", "WebElements:Zn" ; oboInOwl:hasExactSynonym "zinc" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "30Zn", "Zink", "Zn", "Zn(II)", "Zn2+", "cinc", "zinc", "zincum" ; oboInOwl:id "CHEBI:27363" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "zinc atom" ; rdfs:subClassOf obo:CHEBI_33340, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_27364 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "zinc compounds", "zinc molecular entities" ; oboInOwl:id "CHEBI:27364" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "zinc molecular entity" ; rdfs:subClassOf obo:CHEBI_33673, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_27363 ] . obo:CHEBI_27369 obo:IAO_0000115 "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." ; oboInOwl:hasExactSynonym "zwitterion", "zwitterions" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "compose zwitterionique", "compuestos zwitterionicos", "zwitteriones", "zwitterionic compounds" ; oboInOwl:id "CHEBI:27369" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "zwitterion" ; rdfs:subClassOf obo:CHEBI_51151 . obo:CHEBI_27376 obo:IAO_0000115 "An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl." ; chebi:charge "0" ; chebi:formula "CH4O3S" ; chebi:inchi "InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)" ; chebi:inchikey "AFVFQIVMOAPDHO-UHFFFAOYSA-N" ; chebi:mass "96.10666" ; chebi:monoisotopicmass "95.98812" ; chebi:smiles "CS(O)(=O)=O" ; oboInOwl:hasAlternativeId "CHEBI:6813" ; oboInOwl:hasDbXref "Beilstein:1446024", "CAS:75-75-2", "Gmelin:1681", "KEGG:C11145", "MetaCyc:CPD-3746", "PMID:24304088", "PMID:24593036", "Reaxys:1446024", "Wikipedia:Methanesulfonic_acid" ; oboInOwl:hasExactSynonym "Methanesulfonic acid", "methanesulfonic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Methansulfonsaeure", "methylsulfonic acid" ; oboInOwl:id "CHEBI:27376" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methanesulfonic acid" ; rdfs:subClassOf obo:CHEBI_47901, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_25224 ] . obo:CHEBI_27563 chebi:charge "0" ; chebi:formula "As" ; chebi:inchi "InChI=1S/As" ; chebi:inchikey "RQNWIZPPADIBDY-UHFFFAOYSA-N" ; chebi:mass "74.92160" ; chebi:monoisotopicmass "74.92159" ; chebi:smiles "[As]" ; oboInOwl:hasAlternativeId "CHEBI:22630", "CHEBI:2845" ; oboInOwl:hasDbXref "CAS:7440-38-2", "KEGG:C06269", "WebElements:As" ; oboInOwl:hasExactSynonym "arsenic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "33As", "Arsen", "Arsenic", "As", "arsenic", "arsenico", "arsenicum" ; oboInOwl:id "CHEBI:27563" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "arsenic atom" ; rdfs:subClassOf obo:CHEBI_137980, obo:CHEBI_33300, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_27594 chebi:charge "0" ; chebi:formula "C" ; chebi:inchi "InChI=1S/C" ; chebi:inchikey "OKTJSMMVPCPJKN-UHFFFAOYSA-N" ; chebi:mass "12.01070" ; chebi:monoisotopicmass "12.00000" ; chebi:smiles "[C]" ; oboInOwl:hasAlternativeId "CHEBI:23009", "CHEBI:3399" ; oboInOwl:hasDbXref "CAS:7440-44-0", "KEGG:C06265", "WebElements:C" ; oboInOwl:hasExactSynonym "carbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "6C", "C", "Carbon", "Kohlenstoff", "carbon", "carbone", "carbonium", "carbono" ; oboInOwl:id "CHEBI:27594" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbon atom" ; rdfs:subClassOf obo:CHEBI_25585, obo:CHEBI_33306, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_27638 obo:IAO_0000115 "A cobalt group element atom that has atomic number 27." ; chebi:charge "0" ; chebi:formula "Co" ; chebi:inchi "InChI=1S/Co" ; chebi:inchikey "GUTLYIVDDKVIGB-UHFFFAOYSA-N" ; chebi:mass "58.93320" ; chebi:monoisotopicmass "58.93319" ; chebi:smiles "[Co]" ; oboInOwl:hasAlternativeId "CHEBI:23335", "CHEBI:3788" ; oboInOwl:hasDbXref "CAS:7440-48-4", "KEGG:C00175", "KEGG:C19171", "PDBeChem:3CO", "WebElements:Co" ; oboInOwl:hasExactSynonym "cobalt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "27Co", "Co", "Cobalt", "Kobalt", "cobalt", "cobalto", "cobaltum" ; oboInOwl:id "CHEBI:27638" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cobalt atom" ; rdfs:subClassOf obo:CHEBI_33358, obo:CHEBI_88184, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_27682 oboInOwl:hasAlternativeId "CHEBI:1330", "CHEBI:19832" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:27682" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "3',5'-cyclic dGMP" ; rdfs:subClassOf obo:CHEBI_19834 . obo:CHEBI_27732 obo:IAO_0000115 "A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee." ; chebi:charge "0" ; chebi:formula "C8H10N4O2" ; chebi:inchi "InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3" ; chebi:inchikey "RYYVLZVUVIJVGH-UHFFFAOYSA-N" ; chebi:mass "194.19076" ; chebi:monoisotopicmass "194.08038" ; chebi:smiles "Cn1cnc2n(C)c(=O)n(C)c(=O)c12" ; oboInOwl:hasAlternativeId "CHEBI:22982", "CHEBI:3295", "CHEBI:41472" ; oboInOwl:hasDbXref "Beilstein:17705", "CAS:58-08-2", "DrugBank:DB00201", "Drug_Central:463", "Gmelin:103040", "HMDB:HMDB0001847", "KEGG:C07481", "KEGG:D00528", "KNApSAcK:C00001492", "LINCS:LSM-2026", "MetaCyc:1-3-7-TRIMETHYLXANTHINE", "PDBeChem:CFF", "PMID:10510174", "PMID:10796597", "PMID:10803761", "PMID:10822912", "PMID:10884512", "PMID:10924888", "PMID:10983026", "PMID:11014293", "PMID:11022879", "PMID:11209966", "PMID:11312039", "PMID:11410911", "PMID:11431501", "PMID:11815511", "PMID:11949272", "PMID:12397877", "PMID:12457274", "PMID:12574990", "PMID:12915014", "PMID:12943586", "PMID:14521986", "PMID:14607010", "PMID:15257305", "PMID:15280431", "PMID:15681408", "PMID:15718055", "PMID:15840517", "PMID:16143823", "PMID:16391865", "PMID:16528931", "PMID:16644114", "PMID:16709440", "PMID:16805851", "PMID:16856769", "PMID:17132260", "PMID:17387608", "PMID:17508167", "PMID:17724925", "PMID:17932622", "PMID:17957400", "PMID:18068204", "PMID:18258404", "PMID:18421070", "PMID:18513215", "PMID:18625110", "PMID:18647558", "PMID:19007524", "PMID:19047957", "PMID:19084078", "PMID:19088793", "PMID:19418355", "PMID:19879252", "PMID:20164568", "PMID:20470411", "PMID:22114686", "PMID:22770225", "PMID:23551936", "PMID:24039592", "PMID:7441110", "PMID:7689104", "PMID:8332255", "PMID:8347173", "PMID:8679661", "PMID:9063686", "PMID:9067318", "PMID:9132918", "PMID:9218278", "Reaxys:17705", "Wikipedia:Caffeine" ; oboInOwl:hasExactSynonym "1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione", "CAFFEINE", "Caffeine", "caffeine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,3,7-Trimethylxanthine", "1,3,7-trimethyl-2,6-dioxopurine", "1,3,7-trimethylpurine-2,6-dione", "1,3,7-trimethylxanthine", "1-methyltheobromine", "3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion", "7-methyltheophylline", "Coffein", "Koffein", "Thein", "anhydrous caffeine", "cafeina", "cafeine", "guaranine", "mateina", "methyltheobromine", "teina", "theine" ; oboInOwl:id "CHEBI:27732" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "caffeine" ; rdfs:subClassOf obo:CHEBI_27134, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25435 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35337 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35471 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35498 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50218 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50925 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_53121 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_60809 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64047 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_67114 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76946 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_85234 ] . obo:CHEBI_27780 obo:IAO_0000115 "A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions." ; oboInOwl:hasAlternativeId "CHEBI:23648", "CHEBI:4456" ; oboInOwl:hasDbXref "KEGG:C01689" ; oboInOwl:hasExactSynonym "detergent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Detergents" ; oboInOwl:id "CHEBI:27780" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "detergent" ; rdfs:subClassOf obo:CHEBI_33232, obo:CHEBI_35195 . obo:CHEBI_27848 chebi:charge "0" ; chebi:formula "C6H11O5R" ; chebi:mass "163.14850" ; chebi:monoisotopicmass "163.06065" ; chebi:smiles "C[C@@H]1O[C@@H](O[*])[C@H](O)[C@H](O)[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:10294", "CHEBI:22426" ; oboInOwl:hasDbXref "KEGG:C02757" ; oboInOwl:hasExactSynonym "6-deoxy-alpha-L-mannopyranoside", "alpha-L-Rhamnoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-L-rhamnosides" ; oboInOwl:id "CHEBI:27848" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-L-rhamnoside" ; rdfs:subClassOf obo:CHEBI_26547 . obo:CHEBI_27882 obo:IAO_0000115 "A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions." ; chebi:charge "0" ; chebi:formula "C22H25NO6" ; chebi:inchi "InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1" ; chebi:inchikey "IAKHMKGGTNLKSZ-INIZCTEOSA-N" ; chebi:mass "399.443" ; chebi:monoisotopicmass "399.16819" ; chebi:smiles "COC1=CC2=C(C(OC)=C1OC)C1=CC=C(OC)C(=O)C=C1[C@H](CC2)NC(C)=O" ; oboInOwl:hasAlternativeId "CHEBI:3811" ; oboInOwl:hasDbXref "Beilstein:2228813", "CAS:64-86-8", "Chemspider:5933", "DrugBank:DB01394", "Drug_Central:726", "KEGG:C07592", "KEGG:D00570", "KNApSAcK:C00002327", "LINCS:LSM-5199", "MetaCyc:CPD-9785", "PDBeChem:LOC", "PMID:16188942", "PMID:17619668", "PMID:18787557", "PMID:24530796", "PMID:28832953", "PMID:28912485", "PMID:28959419", "PMID:30565859", "PMID:32025680", "PMID:32426001", "PMID:32511763", "PMID:32837853", "PMID:32865380", "PMID:33100196", "PMID:33166069", "Wikipedia:Colchicine" ; oboInOwl:hasExactSynonym "N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-colchicine", "(S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide", "7alphaH-colchicine", "Colchicin", "Colchicine", "Colchisol", "Colcin", "Colcrys", "Colsaloid", "Condylon", "Goutnil", "Kolkicin", "Mitigare", "colchicina", "colchicinum" ; oboInOwl:id "CHEBI:27882" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(S)-colchicine" ; rdfs:subClassOf obo:CHEBI_23359, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25435 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35845 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_67079 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_51074 ] . obo:CHEBI_28024 chebi:charge "0" ; chebi:formula "CHNO" ; chebi:inchi "InChI=1S/CHNO/c2-1-3/h3H" ; chebi:inchikey "XLJMAIOERFSOGZ-UHFFFAOYSA-N" ; chebi:mass "43.025" ; chebi:monoisotopicmass "43.00581" ; chebi:smiles "OC#N" ; oboInOwl:hasAlternativeId "CHEBI:23422", "CHEBI:3968" ; oboInOwl:hasDbXref "Beilstein:1732479", "CAS:420-05-3", "Chemspider:525", "Gmelin:839", "KEGG:C01417", "PDBeChem:0NM", "PMID:12573832", "PMID:12590561", "PMID:16743625", "PMID:16744204", "PMID:19624192", "PMID:20261791", "PMID:20261792", "PMID:20340793", "PMID:237898", "PMID:4368066", "PMID:6493050" ; oboInOwl:hasExactSynonym "Cyanic acid", "hydrogen nitridooxocarbonate", "hydroxidonitridocarbon", "nitridooxocarbonic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cyansaeure", "HOCN", "Zyansaeure", "[C(N)OH]", "acide cyanique", "acido cianico", "acidum cyanicum" ; oboInOwl:id "CHEBI:28024" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyanic acid" ; rdfs:subClassOf obo:CHEBI_23423, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29195 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_29202 ] . obo:CHEBI_28087 obo:IAO_0000115 "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." ; oboInOwl:hasAlternativeId "CHEBI:24379", "CHEBI:5466" ; oboInOwl:hasDbXref "CAS:9005-79-2", "GlyGen:G99991IU", "GlyTouCan:G99991IU", "HMDB:HMDB0000757", "KEGG:C00182", "MetaCyc:CPD0-971", "Wikipedia:Glycogen" ; oboInOwl:hasExactSynonym "Glycogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1", "animal starch", "liver starch" ; oboInOwl:id "CHEBI:28087" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycogen" ; rdfs:subClassOf obo:CHEBI_24384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_28112 obo:IAO_0000115 "Chemical element (nickel group element atom) with atomic number 28." ; chebi:charge "0" ; chebi:formula "Ni" ; chebi:inchi "InChI=1S/Ni" ; chebi:inchikey "PXHVJJICTQNCMI-UHFFFAOYSA-N" ; chebi:mass "58.69340" ; chebi:monoisotopicmass "57.93534" ; chebi:smiles "[Ni]" ; oboInOwl:hasAlternativeId "CHEBI:25515", "CHEBI:7552" ; oboInOwl:hasDbXref "CAS:7440-02-0", "Gmelin:16229", "KEGG:C00291", "PMID:12756270", "PMID:14634084", "PMID:14734778", "PMID:15165199", "PMID:19828094", "PMID:20477134", "PMID:22762130", "PMID:23142754", "PMID:23317102", "PMID:23692032", "PMID:23692035", "PMID:23723488", "PMID:23834453", "PMID:23857010", "PMID:23895079", "PMID:23909687", "PMID:9060994", "PMID:9886425", "Reaxys:4122946", "WebElements:Ni", "Wikipedia:Nickel" ; oboInOwl:hasExactSynonym "nickel" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "28Ni", "Ni", "Nickel", "Raney alloy", "niccolum", "nickel", "niquel" ; oboInOwl:id "CHEBI:28112" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nickel atom" ; rdfs:subClassOf obo:CHEBI_33362, obo:CHEBI_88184, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_53000 ] . obo:CHEBI_2814 obo:IAO_0000115 "A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine." ; chebi:charge "0" ; chebi:formula "C8H13NO2" ; chebi:inchi "InChI=1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3" ; chebi:inchikey "HJJPJSXJAXAIPN-UHFFFAOYSA-N" ; chebi:mass "155.19430" ; chebi:monoisotopicmass "155.09463" ; chebi:smiles "COC(=O)C1=CCCN(C)C1" ; oboInOwl:hasDbXref "CAS:63-75-2", "DrugBank:DB04365", "HMDB:HMDB0030353", "KEGG:C10129", "KNApSAcK:C00002020", "LINCS:LSM-15214", "PMID:21809341", "PMID:22493525", "PMID:23525646", "PMID:23895157", "Patent:CN101411705", "Patent:CN102464607", "Patent:US2506458", "Reaxys:123045", "Wikipedia:Arecoline" ; oboInOwl:hasExactSynonym "methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "arecaidine methyl ester", "arecaline", "arecholine", "arekolin", "methylarecaiden", "methylarecaidin" ; oboInOwl:id "CHEBI:2814" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "arecoline" ; rdfs:subClassOf obo:CHEBI_25248, obo:CHEBI_26416, obo:CHEBI_26921, obo:CHEBI_51702, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38325 ] . obo:CHEBI_28260 obo:IAO_0000115 "An aldohexose that is the C-4 epimer of glucose." ; chebi:charge "0" ; chebi:formula "C6H12O6" ; chebi:mass "180.156" ; chebi:monoisotopicmass "180.06339" ; oboInOwl:hasAlternativeId "CHEBI:24162", "CHEBI:33933", "CHEBI:5256" ; oboInOwl:hasDbXref "CAS:26566-61-0", "KEGG:C01582", "Wikipedia:Galactose" ; oboInOwl:hasExactSynonym "Galactose", "galacto-hexose", "galactose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Gal", "Galaktose" ; oboInOwl:id "CHEBI:28260" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "galactose" ; rdfs:subClassOf obo:CHEBI_33917, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ] . obo:CHEBI_28616 obo:IAO_0000115 "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." ; chebi:charge "0" ; chebi:formula "CH3NO2" ; chebi:inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)" ; chebi:inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-N" ; chebi:mass "61.04006" ; chebi:monoisotopicmass "61.01638" ; chebi:smiles "NC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:22504", "CHEBI:23002", "CHEBI:3386", "CHEBI:44573" ; oboInOwl:hasDbXref "Beilstein:1734754", "CAS:463-77-4", "DrugBank:DB04261", "Gmelin:130345", "KEGG:C01563", "PDBeChem:OUT", "Wikipedia:Carbamic_acid" ; oboInOwl:hasExactSynonym "CARBAMIC ACID", "Carbamic acid", "carbamic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aminoameisensaeure", "Aminoformic acid", "Carbamate", "Carbamidsaeure" ; oboInOwl:id "CHEBI:28616" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbamic acid" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_35605, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_13941 ] . obo:CHEBI_28659 chebi:charge "0" ; chebi:formula "P" ; chebi:inchi "InChI=1S/P" ; chebi:inchikey "OAICVXFJPJFONN-UHFFFAOYSA-N" ; chebi:mass "30.97376" ; chebi:monoisotopicmass "30.97376" ; chebi:smiles "[P]" ; oboInOwl:hasAlternativeId "CHEBI:26080", "CHEBI:8168" ; oboInOwl:hasDbXref "CAS:7723-14-0", "Gmelin:16235", "KEGG:C06262", "WebElements:P" ; oboInOwl:hasExactSynonym "phosphorus" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "15P", "P", "Phosphor", "Phosphorus", "fosforo", "phosphore", "phosphorus" ; oboInOwl:id "CHEBI:28659" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphorus atom" ; rdfs:subClassOf obo:CHEBI_25585, obo:CHEBI_33300, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_28694 chebi:charge "0" ; chebi:formula "Cu" ; chebi:inchi "InChI=1S/Cu" ; chebi:inchikey "RYGMFSIKBFXOCR-UHFFFAOYSA-N" ; chebi:mass "63.54600" ; chebi:monoisotopicmass "62.92960" ; chebi:smiles "[Cu]" ; oboInOwl:hasAlternativeId "CHEBI:23376", "CHEBI:3874" ; oboInOwl:hasDbXref "CAS:7440-50-8", "Gmelin:16269", "KEGG:C00070", "WebElements:Cu" ; oboInOwl:hasExactSynonym "copper" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "29Cu", "Copper", "Cu", "Kupfer", "cobre", "copper", "cuivre", "cuprum" ; oboInOwl:id "CHEBI:28694" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "copper atom" ; rdfs:subClassOf obo:CHEBI_33366, obo:CHEBI_88184, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_28765 obo:IAO_0000115 "Any member of the phosphoinositide family of compounds, of which seven occur naturally." ; oboInOwl:hasAlternativeId "CHEBI:26037", "CHEBI:26038", "CHEBI:8135" ; oboInOwl:hasDbXref "PMID:16441841", "PMID:2538726" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "phosphatidylinositol phosphates" ; oboInOwl:id "CHEBI:28765" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphatidylinositol phosphate" ; rdfs:subClassOf obo:CHEBI_18179 . obo:CHEBI_28790 obo:IAO_0000115 "A primary amino compound that is the 5-hydroxy derivative of tryptamine." ; chebi:charge "0" ; chebi:formula "C10H12N2O" ; chebi:inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2" ; chebi:inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-N" ; chebi:mass "176.215" ; chebi:monoisotopicmass "176.09496" ; chebi:smiles "C1=CC(=CC=2C(=CNC12)CCN)O" ; oboInOwl:hasAlternativeId "CHEBI:1420", "CHEBI:26652", "CHEBI:49894" ; oboInOwl:hasDbXref "Beilstein:143524", "CAS:50-67-9", "Gmelin:1861995", "HMDB:HMDB0000259", "KEGG:C00780", "KNApSAcK:C00001429", "LINCS:LSM-6589", "MetaCyc:SEROTONIN", "PDBeChem:SRO", "PMID:18593914", "PMID:22770225", "PMID:24136337", "Reaxys:143524", "Wikipedia:Serotonin" ; oboInOwl:hasExactSynonym "3-(2-aminoethyl)-1H-indol-5-ol", "SEROTONIN", "Serotonin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3-(2-Aminoethyl)-1H-indol-5-ol", "5-HT", "5-Hydroxytryptamine", "Enteramine", "serotonine", "thrombocytin", "thrombotonin" ; oboInOwl:id "CHEBI:28790" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "serotonin" ; rdfs:subClassOf obo:CHEBI_25375, obo:CHEBI_27162, obo:CHEBI_33853, obo:CHEBI_50994, obo:CHEBI_84729, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25512 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16765 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_350546 ] . obo:CHEBI_28868 obo:IAO_0000115 "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.00950" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13634", "CHEBI:24022", "CHEBI:4985" ; oboInOwl:hasDbXref "KEGG:C02403", "PMID:18628202" ; oboInOwl:hasExactSynonym "Fatty acid anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Alkanate", "Fettsaeureanion", "Fettsaeureanionen", "a fatty acid", "acido graso anionico", "acidos grasos anionicos", "anion de l'acide gras", "fatty acid anions" ; oboInOwl:id "CHEBI:28868" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fatty acid anion" ; rdfs:subClassOf obo:CHEBI_18059, obo:CHEBI_35757, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35366 ] . obo:CHEBI_28874 obo:IAO_0000115 "Any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol." ; oboInOwl:hasAlternativeId "CHEBI:18877", "CHEBI:494" ; oboInOwl:hasDbXref "DrugBank:DB02144", "PMID:15634688", "PMID:15967713", "PMID:17417879", "PMID:18189424", "PMID:19456874", "PMID:23015060", "PMID:23118092", "Wikipedia:Phosphatidylinositol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "PI", "PtdIns", "phosphatidylinositols" ; oboInOwl:id "CHEBI:28874" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphatidylinositol" ; rdfs:subClassOf obo:CHEBI_36315 . obo:CHEBI_28938 obo:IAO_0000115 "An onium cation obtained by protonation of ammonia." ; chebi:charge "+1" ; chebi:formula "H4N" ; chebi:inchi "InChI=1S/H3N/h1H3/p+1" ; chebi:inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-O" ; chebi:mass "18.03850" ; chebi:monoisotopicmass "18.03383" ; chebi:smiles "[H][N+]([H])([H])[H]" ; oboInOwl:hasAlternativeId "CHEBI:22534", "CHEBI:49783", "CHEBI:7435" ; oboInOwl:hasDbXref "CAS:14798-03-9", "Gmelin:84", "KEGG:C01342", "MetaCyc:AMMONIUM", "MolBase:929", "PDBeChem:NH4", "PMID:11319011", "PMID:11341317", "PMID:12096804", "PMID:14512268", "PMID:14879753", "PMID:16345391", "PMID:16903292", "PMID:17392693", "PMID:18515490", "PMID:19199063", "PMID:19596600", "PMID:19682559", "PMID:19716251", "PMID:21993530", "PMID:22265469", "PMID:22524020", "PMID:22562341", "PMID:22631217", "Reaxys:16093784", "Wikipedia:Ammonium" ; oboInOwl:hasExactSynonym "ammonium", "azanium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ammonium(1+)", "NH4(+)", "NH4+", "[NH4](+)", "ammonium cation", "ammonium ion" ; oboInOwl:id "CHEBI:28938" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ammonium" ; rdfs:subClassOf obo:CHEBI_35106, obo:CHEBI_50313, obo:CHEBI_60242, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16134 ] . obo:CHEBI_28965 obo:IAO_0000115 "A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid." ; chebi:charge "-2" ; chebi:formula "C2O4R" ; chebi:mass "88.019" ; chebi:monoisotopicmass "87.97966" ; chebi:smiles "[O-]C(=O)[*]C([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:13632", "CHEBI:23688", "CHEBI:23689", "CHEBI:38711" ; oboInOwl:hasExactSynonym "dicarboxylic acid dianion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a dicarboxylate", "dicarboxylate", "dicarboxylates", "dicarboxylic acid dianions" ; oboInOwl:id "CHEBI:28965" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dicarboxylic acid dianion" ; rdfs:subClassOf obo:CHEBI_35693, obo:CHEBI_38716 . obo:CHEBI_28976 chebi:charge "0" ; chebi:formula "CH2O3" ; chebi:inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)" ; chebi:inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-N" ; chebi:mass "62.02478" ; chebi:monoisotopicmass "62.00039" ; chebi:smiles "OC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:13351", "CHEBI:23017", "CHEBI:23744", "CHEBI:3401" ; oboInOwl:hasDbXref "CAS:463-79-6", "Gmelin:25554", "KEGG:C01353", "PDBeChem:CO3" ; oboInOwl:hasExactSynonym "Carbonic acid", "carbonic acid", "dihydroxidooxidocarbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Dihydrogen carbonate", "H2CO3", "Koehlensaeure", "[CO(OH)2]" ; oboInOwl:id "CHEBI:28976" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbonic acid" ; rdfs:subClassOf obo:CHEBI_35605, obo:CHEBI_36961, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17544 ] . obo:CHEBI_29067 obo:IAO_0000115 "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.00950" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13626", "CHEBI:13945", "CHEBI:23026", "CHEBI:58657" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a carboxylate", "carboxylic acid anions", "carboxylic anions" ; oboInOwl:id "CHEBI:29067" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carboxylic acid anion" ; rdfs:subClassOf obo:CHEBI_25696, obo:CHEBI_35406, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33575 ] . obo:CHEBI_29075 chebi:charge "0" ; chebi:formula "C5H10O7PR" ; chebi:mass "213.103" ; chebi:monoisotopicmass "213.01641" ; oboInOwl:hasAlternativeId "CHEBI:14616", "CHEBI:25404", "CHEBI:6983" ; oboInOwl:hasDbXref "KEGG:C02171" ; oboInOwl:hasExactSynonym "Mononucleotide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mononucleotides" ; oboInOwl:id "CHEBI:29075" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mononucleotide" ; rdfs:subClassOf obo:CHEBI_36976 . obo:CHEBI_29101 obo:IAO_0000115 "A monoatomic monocation obtained from sodium." ; chebi:charge "+1" ; chebi:formula "Na" ; chebi:inchi "InChI=1S/Na/q+1" ; chebi:inchikey "FKNQFGJONOIPTF-UHFFFAOYSA-N" ; chebi:mass "22.98977" ; chebi:monoisotopicmass "22.98922" ; chebi:smiles "[Na+]" ; oboInOwl:hasAlternativeId "CHEBI:26717", "CHEBI:49766", "CHEBI:9175" ; oboInOwl:hasDbXref "CAS:17341-25-2", "Gmelin:15196", "KEGG:C01330", "PDBeChem:NA" ; oboInOwl:hasExactSynonym "sodium cation", "sodium(1+)", "sodium(1+) ion", "sodium(I) cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Na(+)", "Na+", "SODIUM ION" ; oboInOwl:id "CHEBI:29101" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sodium(1+)" ; rdfs:subClassOf obo:CHEBI_25414, obo:CHEBI_33504, obo:CHEBI_37246, obo:CHEBI_60242, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ] . obo:CHEBI_29108 chebi:charge "+2" ; chebi:formula "Ca" ; chebi:inchi "InChI=1S/Ca/q+2" ; chebi:inchikey "BHPQYMZQTOCNFJ-UHFFFAOYSA-N" ; chebi:mass "40.07800" ; chebi:monoisotopicmass "39.96149" ; chebi:smiles "[Ca++]" ; oboInOwl:hasAlternativeId "CHEBI:22988", "CHEBI:3308", "CHEBI:48760" ; oboInOwl:hasDbXref "CAS:14127-61-8", "Gmelin:6850", "KEGG:C00076", "PDBeChem:CA" ; oboInOwl:hasExactSynonym "calcium(2+)", "calcium(2+) ion", "calcium(II) cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CALCIUM ION", "Ca(2+)", "Ca2+", "calcium, doubly charged positive ion" ; oboInOwl:id "CHEBI:29108" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "calcium(2+)" ; rdfs:subClassOf obo:CHEBI_30412, obo:CHEBI_39123, obo:CHEBI_60240, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ] . obo:CHEBI_29192 chebi:charge "-1" ; chebi:formula "HO2" ; chebi:inchi "InChI=1S/H2O2/c1-2/h1-2H/p-1" ; chebi:inchikey "MHAJPDPJQMAIIY-UHFFFAOYSA-M" ; chebi:mass "33.00674" ; chebi:monoisotopicmass "32.99820" ; chebi:smiles "[H]O[O-]" ; oboInOwl:hasDbXref "CAS:14691-59-9", "Gmelin:507" ; oboInOwl:hasExactSynonym "dioxidanide", "hydrogen(peroxide)(1-)", "hydrogendioxide(1-)", "hydrogenperoxide(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HO2(-)", "HOO anion", "HOO(-)", "[HO2](-)" ; oboInOwl:id "CHEBI:29192" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogenperoxide(1-)" ; rdfs:subClassOf obo:CHEBI_33693, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16240 ] . obo:CHEBI_29195 chebi:charge "-1" ; chebi:formula "CNO" ; chebi:inchi "InChI=1S/CHNO/c2-1-3/h3H/p-1" ; chebi:inchikey "XLJMAIOERFSOGZ-UHFFFAOYSA-M" ; chebi:mass "42.01684" ; chebi:monoisotopicmass "41.99854" ; chebi:smiles "[O-]C#N" ; oboInOwl:hasAlternativeId "CHEBI:14037", "CHEBI:23419" ; oboInOwl:hasDbXref "CAS:661-20-1", "CAS:71000-82-3", "FooDB:FDB022835", "HMDB:HMDB0002078", "KEGG:C01417", "MetaCyc:CPD-69", "PMID:8323034", "UM-BBD_compID:c0568" ; oboInOwl:hasExactSynonym "cyanate", "nitridooxidocarbonate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cyanat", "OCN(-)", "Zyanat", "[C(N)O](-)", "cyanate ion" ; oboInOwl:id "CHEBI:29195" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyanate" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_36828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_28024 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29202 ] . obo:CHEBI_29202 obo:IAO_0000115 "A colourless, volatile, poisonous inorganic compound with the formula HNCO; the simplest stable chemical compound that contains carbon, hydrogen, nitrogen, and oxygen, the four most commonly-found elements in organic chemistry and biology." ; chebi:charge "0" ; chebi:formula "CHNO" ; chebi:inchi "InChI=1S/CHNO/c2-1-3/h2H" ; chebi:inchikey "OWIKHYCFFJSOEH-UHFFFAOYSA-N" ; chebi:mass "43.02478" ; chebi:monoisotopicmass "43.00581" ; chebi:smiles "N=C=O" ; oboInOwl:hasDbXref "Beilstein:1616281", "CAS:75-13-8", "Gmelin:840", "PMID:19494520", "PMID:26124058", "PMID:26760716", "PMID:977566", "Reaxys:1616281" ; oboInOwl:hasExactSynonym "isocyanic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HN=C=O", "HNCO", "ICA", "[C(NH)O]", "carbimide", "hydrogen isocyanate", "isocyanate", "isocyansaeure", "isozyansaeure", "methenamide", "oxidoazanediidocarbon" ; oboInOwl:id "CHEBI:29202" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isocyanic acid" ; rdfs:subClassOf obo:CHEBI_33405, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29195 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_28024 ] . obo:CHEBI_29214 chebi:charge "0" ; chebi:formula "H2O3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)" ; chebi:inchikey "BDHFUVZGWQCTTF-UHFFFAOYSA-N" ; chebi:mass "82.08008" ; chebi:monoisotopicmass "81.97247" ; chebi:smiles "[H]S(O)(=O)=O" ; oboInOwl:hasDbXref "Gmelin:1404640" ; oboInOwl:hasExactSynonym "hydridohydroxidodioxidosulfur", "sulfonic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HSHO3", "Sulfonsaeure", "[SHO2(OH)]", "acide sulfonique", "sulphonic acid" ; oboInOwl:id "CHEBI:29214" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfonic acid" ; rdfs:subClassOf obo:CHEBI_33402, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33543 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_48854 ] . obo:CHEBI_29222 chebi:charge "-1" ; chebi:formula "ClO" ; chebi:inchi "InChI=1S/ClO/c1-2/q-1" ; chebi:inchikey "WQYVRQLZKVEZGA-UHFFFAOYSA-N" ; chebi:mass "51.45210" ; chebi:monoisotopicmass "50.96432" ; chebi:smiles "[O-]Cl" ; oboInOwl:hasDbXref "CAS:14380-61-1", "Gmelin:682", "Wikipedia:Hypochlorite" ; oboInOwl:hasExactSynonym "hypochlorite", "oxidochlorate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ClO(-)", "Hypochlorit", "[ClO](-)" ; oboInOwl:id "CHEBI:29222" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hypochlorite" ; rdfs:subClassOf obo:CHEBI_33437, obo:CHEBI_37750, obo:CHEBI_79389, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_24757 ] . obo:CHEBI_29228 obo:IAO_0000115 "A diatomic molecule containing covalently bonded hydrogen and fluorine atoms." ; chebi:charge "0" ; chebi:formula "FH" ; chebi:inchi "InChI=1S/FH/h1H" ; chebi:inchikey "KRHYYFGTRYWZRS-UHFFFAOYSA-N" ; chebi:mass "20.00634" ; chebi:monoisotopicmass "20.00623" ; chebi:smiles "F[H]" ; oboInOwl:hasDbXref "CAS:7664-39-3", "Drug_Central:4499", "Gmelin:166", "KEGG:C16487" ; oboInOwl:hasExactSynonym "Hydrogen fluoride", "fluorane", "fluoridohydrogen", "hydrogen fluoride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Fluoride", "Fluorwasserstoff", "HF", "Hydrogenfluorid", "[HF]", "fluorure d'hydrogene", "hydrofluoric acid" ; oboInOwl:id "CHEBI:29228" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogen fluoride" ; rdfs:subClassOf obo:CHEBI_18140, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17051 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_50314 ] . obo:CHEBI_29256 obo:IAO_0000115 "An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety." ; chebi:charge "0" ; chebi:formula "HSR" ; chebi:mass "33.07300" ; chebi:monoisotopicmass "32.97990" ; chebi:smiles "S[*]" ; oboInOwl:hasAlternativeId "CHEBI:13443", "CHEBI:13696", "CHEBI:17366", "CHEBI:26969", "CHEBI:8766", "CHEBI:9556" ; oboInOwl:hasDbXref "KEGG:C00145", "Wikipedia:Thiol" ; oboInOwl:hasExactSynonym "Thiol", "thiols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Mercaptan", "Merkaptan", "RSH", "a thiol", "mercaptans", "thiols" ; oboInOwl:id "CHEBI:29256" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "thiol" ; rdfs:subClassOf obo:CHEBI_33261, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29917 ] . obo:CHEBI_29337 chebi:charge "-1" ; chebi:formula "H2N" ; chebi:inchi "InChI=1S/H2N/h1H2/q-1" ; chebi:inchikey "HYGWNUKOUCZBND-UHFFFAOYSA-N" ; chebi:mass "16.02262" ; chebi:monoisotopicmass "16.01927" ; chebi:smiles "[H][N-][H]" ; oboInOwl:hasExactSynonym "amide", "azanide", "dihydridonitrate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NH2(-)" ; oboInOwl:id "CHEBI:29337" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "azanide" ; rdfs:subClassOf obo:CHEBI_35106, obo:CHEBI_79389, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29340 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16134 ] . obo:CHEBI_29340 obo:IAO_0000115 "A divalent inorganic anion resulting from the removal of two protons from ammonia." ; chebi:charge "-2" ; chebi:formula "HN" ; chebi:inchi "InChI=1S/HN/h1H/q-2" ; chebi:inchikey "DZQYTNGKSBCIOE-UHFFFAOYSA-N" ; chebi:mass "15.01468" ; chebi:monoisotopicmass "15.01200" ; chebi:smiles "[N--][H]" ; oboInOwl:hasExactSynonym "azanediide", "hydridonitrate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NH(2-)", "imide" ; oboInOwl:id "CHEBI:29340" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydridonitrate(2-)" ; rdfs:subClassOf obo:CHEBI_35106, obo:CHEBI_79388, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29337 ] . obo:CHEBI_29347 obo:IAO_0000115 "A carboxamide derived from a monocarboxylic acid." ; chebi:charge "0" ; chebi:formula "CNOR3" ; chebi:mass "42.01680" ; chebi:monoisotopicmass "41.99799" ; chebi:smiles "[*]N([*])C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13211", "CHEBI:22207", "CHEBI:25383", "CHEBI:6977" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monocarboxylic acid amides" ; oboInOwl:id "CHEBI:29347" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monocarboxylic acid amide" ; rdfs:subClassOf obo:CHEBI_37622 . obo:CHEBI_29360 chebi:charge "-2" ; chebi:formula "CH2" ; chebi:inchi "InChI=1S/CH2/h1H2/q-2" ; chebi:inchikey "PZPOWPOFQLSNJO-UHFFFAOYSA-N" ; chebi:mass "14.02658" ; chebi:monoisotopicmass "14.01675" ; chebi:smiles "[H][C--][H]" ; oboInOwl:hasDbXref "Beilstein:5915711", "Gmelin:322698" ; oboInOwl:hasExactSynonym "dihydridocarbonate(2-)", "methanediide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH2(2-)", "[CH2](2-)" ; oboInOwl:id "CHEBI:29360" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methanediide" ; rdfs:subClassOf obo:CHEBI_38222, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29438 ] . obo:CHEBI_29369 chebi:charge "0" ; chebi:formula "O2" ; chebi:mass "31.99880" ; chebi:monoisotopicmass "31.98983" ; chebi:smiles "O(O*)*" ; oboInOwl:hasExactSynonym "peroxy" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-OO-" ; oboInOwl:id "CHEBI:29369" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "peroxy group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:CHEBI_29438 chebi:charge "-1" ; chebi:formula "CH3" ; chebi:inchi "InChI=1S/CH3/h1H3/q-1" ; chebi:inchikey "LGRLWUINFJPLSH-UHFFFAOYSA-N" ; chebi:mass "15.03452" ; chebi:monoisotopicmass "15.02402" ; chebi:smiles "[H][C-]([H])[H]" ; oboInOwl:hasDbXref "Beilstein:1813938", "CAS:15194-58-8", "Gmelin:259263" ; oboInOwl:hasExactSynonym "methanide", "trihydridocarbonate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3(-)", "[CH3](-)", "lambda(2)-methanuide", "methyl anion" ; oboInOwl:id "CHEBI:29438" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methanide" ; rdfs:subClassOf obo:CHEBI_38222, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29360 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16183 ] . obo:CHEBI_29534 chebi:charge "0" ; chebi:formula "C48H72O14" ; chebi:inchi "InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1" ; chebi:inchikey "RRZXIRBKKLTSOM-XPNPUAGNSA-N" ; chebi:mass "873.07690" ; chebi:monoisotopicmass "872.49221" ; chebi:smiles "CC[C@H](C)[C@H]1O[C@@]2(C[C@@H]3C[C@@H](C\\C=C(C)\\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\\C=C\\C=C4/CO[C@@H]5[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)C=C[C@@H]1C" ; oboInOwl:hasDbXref "BPDB:8", "Beilstein:3645625", "CAS:65195-55-3", "KEGG:C11983", "LIPID_MAPS_instance:LMPK04000024", "MetaCyc:CPD-12963", "VSDB:8" ; oboInOwl:hasExactSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside", "Avermectin B1a" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "abamectin component B1a" ; oboInOwl:id "CHEBI:29534" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "avermectin B1a" ; rdfs:subClassOf obo:CHEBI_50344 . obo:CHEBI_29537 chebi:charge "0" ; chebi:formula "C47H70O14" ; chebi:inchi "InChI=1S/C47H70O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,16-18,24-25,27,29-30,32-44,48-49,51H,15,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m0/s1" ; chebi:inchikey "ZFUKERYTFURFGA-PVVXTEPVSA-N" ; chebi:mass "859.05030" ; chebi:monoisotopicmass "858.47656" ; chebi:smiles "[H][C@@]12C\\C=C(C)\\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\\C=C\\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(O2)O[C@]([H])(C(C)C)[C@@H](C)C=C1)[C@]34O" ; oboInOwl:hasDbXref "Beilstein:8399072", "CAS:65195-56-4", "KEGG:C11967", "LIPID_MAPS_instance:LMPK04000020", "MetaCyc:CPD-12964" ; oboInOwl:hasExactSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-6'-(propan-2-yl)-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside", "Avermectin B1b" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-6'-isopropyl-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside", "abamectin component B1b" ; oboInOwl:id "CHEBI:29537" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "avermectin B1b" ; rdfs:subClassOf obo:CHEBI_50344 . obo:CHEBI_29699 obo:IAO_0000115 "A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety." ; chebi:charge "0" ; chebi:formula "C25H38N4O16" ; chebi:mass "650.587" ; chebi:monoisotopicmass "650.22828" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](OC2O[C@H]([*]O)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC([*])=O)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "CAS:11089-65-9", "KEGG:C12063", "PMID:11478581", "PMID:11514096", "PMID:11732194", "PMID:11798249", "PMID:12093793", "PMID:12106388", "PMID:12136966", "PMID:12232600", "PMID:12232799", "PMID:12515321", "PMID:160437", "PMID:1624425", "PMID:3018444", "PMID:315774", "PMID:34700340", "PMID:34979291", "PMID:35233582", "PMID:35370192", "PMID:4624615", "PMID:4630978", "PMID:5103138", "PMID:5103535", "PMID:5168706", "PMID:6153524", "PMID:6813319", "PMID:6975776", "PMID:6992777", "PMID:701277", "PMID:7142115", "PMID:7144800", "PMID:7766032", "Wikipedia:Tunicamycin" ; oboInOwl:hasExactSynonym "Tunicamycin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:29699" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin" ; rdfs:subClassOf obo:CHEBI_60004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64228 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64245 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64246 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64248 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64250 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64255 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64256 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64257 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64271 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64272 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64237 ] . obo:CHEBI_29793 chebi:charge "+1" ; chebi:formula "HO2" ; chebi:inchi "InChI=1S/O2/c1-2/p+1" ; chebi:inchikey "MYMOFIZGZYHOMD-UHFFFAOYSA-O" ; chebi:mass "33.00674" ; chebi:monoisotopicmass "32.99711" ; chebi:smiles "[H][O+]=O" ; oboInOwl:hasDbXref "Gmelin:508" ; oboInOwl:hasExactSynonym "dioxidenium", "hydridodioxygen(1+)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HO2(+)", "HOO(+)", "[HO2](+)" ; oboInOwl:id "CHEBI:29793" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydridodioxygen(1+)" ; rdfs:subClassOf obo:CHEBI_33693, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15379 ] . obo:CHEBI_29917 chebi:charge "0" ; chebi:formula "HS" ; chebi:mass "33.074" ; chebi:monoisotopicmass "32.97990" ; chebi:smiles "*S[H]" ; oboInOwl:hasAlternativeId "CHEBI:26821", "CHEBI:29916" ; oboInOwl:hasExactSynonym "sulfanyl", "thiol", "thiol group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-SH", "HS-", "Mercaptogruppe", "Merkaptogruppe", "Sulfhydrylgruppe", "Thiolgruppe", "mercapto group", "sulfhydryl group", "sulphydryl group" ; oboInOwl:id "CHEBI:29917" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "thiol group" ; rdfs:subClassOf obo:CHEBI_33246, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_16136 ] . obo:CHEBI_29919 chebi:charge "-1" ; chebi:formula "HS" ; chebi:inchi "InChI=1S/H2S/h1H2/p-1" ; chebi:inchikey "RWSOTUBLDIXVET-UHFFFAOYSA-M" ; chebi:mass "33.07394" ; chebi:monoisotopicmass "32.98044" ; chebi:smiles "[S-][H]" ; oboInOwl:hasDbXref "CAS:15035-72-0", "Gmelin:24766" ; oboInOwl:hasExactSynonym "hydrogen(sulfide)(1-)", "hydrosulfide", "sulfanide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HS anion", "HS(-)", "hydrogen sulfide" ; oboInOwl:id "CHEBI:29919" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrosulfide" ; rdfs:subClassOf obo:CHEBI_33535, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15138 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16136 ] . obo:CHEBI_29922 chebi:charge "0" ; chebi:formula "HO3S" ; chebi:mass "81.07214" ; chebi:monoisotopicmass "80.96464" ; chebi:smiles "S(=O)(O)(*)=O" ; oboInOwl:hasDbXref "PDBeChem:SFO" ; oboInOwl:hasExactSynonym "SULFO GROUP", "hydroxydioxo-lambda(6)-sulfanyl", "hydroxysulfonyl", "sulfo" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-S(O)2(OH)" ; oboInOwl:id "CHEBI:29922" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfo group" ; rdfs:subClassOf obo:CHEBI_33246, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_29214 ] . obo:CHEBI_30052 chebi:charge "0" ; chebi:formula "Cu" ; chebi:inchi "InChI=1S/Cu" ; chebi:inchikey "RYGMFSIKBFXOCR-UHFFFAOYSA-N" ; chebi:mass "63.54600" ; chebi:monoisotopicmass "62.92960" ; chebi:smiles "[Cu]" ; oboInOwl:hasDbXref "CAS:7440-50-8" ; oboInOwl:hasExactSynonym "copper", "copper(0)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cu(0)", "Cun" ; oboInOwl:id "CHEBI:30052" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "copper(0)" ; rdfs:subClassOf obo:CHEBI_37404 . obo:CHEBI_30089 obo:IAO_0000115 "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." ; chebi:charge "-1" ; chebi:formula "C2H3O2" ; chebi:inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1" ; chebi:inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-M" ; chebi:mass "59.04402" ; chebi:monoisotopicmass "59.01385" ; chebi:smiles "CC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:13704", "CHEBI:22165", "CHEBI:40480" ; oboInOwl:hasDbXref "Beilstein:1901470", "CAS:71-50-1", "DrugBank:DB03166", "Gmelin:1379", "KEGG:C00033", "MetaCyc:ACET", "PDBeChem:ACT", "PMID:17190852", "PMID:22211106", "PMID:22371380", "Reaxys:1901470", "UM-BBD_compID:c0050", "Wikipedia:Acetate" ; oboInOwl:hasExactSynonym "acetate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ACETATE ION", "Azetat", "CH3-COO(-)", "Ethanoat", "MeCO2 anion", "acetic acid, ion(1-)", "ethanoate" ; oboInOwl:id "CHEBI:30089" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acetate" ; rdfs:subClassOf obo:CHEBI_35757, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_15366 ] . obo:CHEBI_30145 chebi:charge "0" ; chebi:formula "Li" ; chebi:inchi "InChI=1S/Li" ; chebi:inchikey "WHXSMMKQMYFTQS-UHFFFAOYSA-N" ; chebi:mass "6.94100" ; chebi:monoisotopicmass "7.01600" ; chebi:smiles "[Li]" ; oboInOwl:hasDbXref "CAS:7439-93-2", "WebElements:Li" ; oboInOwl:hasExactSynonym "lithium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3Li", "Li", "Lithium", "lithium", "litio" ; oboInOwl:id "CHEBI:30145" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "lithium atom" ; rdfs:subClassOf obo:CHEBI_22314 . obo:CHEBI_30185 chebi:charge "0" ; chebi:formula "Zn" ; chebi:inchi "InChI=1S/Zn" ; chebi:inchikey "HCHKCACWOHOZIP-UHFFFAOYSA-N" ; chebi:mass "65.39000" ; chebi:monoisotopicmass "63.92914" ; chebi:smiles "[Zn]" ; oboInOwl:hasDbXref "CAS:7440-66-6", "DrugBank:DB01593" ; oboInOwl:hasExactSynonym "zinc(0)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Zn(0)", "Znn", "zinc" ; oboInOwl:id "CHEBI:30185" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "zinc(0)" ; rdfs:subClassOf obo:CHEBI_37253 . obo:CHEBI_30212 obo:IAO_0000115 "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force." ; chebi:charge "0" ; chebi:mass "0.0" ; chebi:monoisotopicmass "0.0" ; chebi:smiles "*" ; oboInOwl:hasAlternativeId "CHEBI:10581", "CHEBI:14383" ; oboInOwl:hasDbXref "KEGG:C00205" ; oboInOwl:hasExactSynonym "photon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Lichtquant", "Light", "foton", "gamma", "hnu", "light quantum" ; oboInOwl:id "CHEBI:30212" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "photon" ; rdfs:subClassOf obo:CHEBI_36341 . obo:CHEBI_30297 obo:IAO_0000115 "A trivalent inorganic anion obtained by removal of all three protons from antimonous acid." ; chebi:charge "-3" ; chebi:formula "O3Sb" ; chebi:inchi "InChI=1S/3O.Sb/q3*-1;" ; chebi:inchikey "JXYAODGLKNBUTA-UHFFFAOYSA-N" ; chebi:mass "169.75820" ; chebi:monoisotopicmass "168.89020" ; chebi:smiles "[O-][Sb]([O-])[O-]" ; oboInOwl:hasDbXref "PMID:17419726" ; oboInOwl:hasExactSynonym "antimonite", "trioxidoantimonate(3-)", "trioxoantimonate(3-)", "trioxoantimonate(III)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SbO3(3-)", "[SbO3](3-)" ; oboInOwl:id "CHEBI:30297" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimonite" ; rdfs:subClassOf obo:CHEBI_36921, obo:CHEBI_79387, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_49870 ] . obo:CHEBI_30320 chebi:charge "-1" ; chebi:formula "C2H3OS" ; chebi:inchi "InChI=1S/C2H4OS/c1-2(3)4/h1H3,(H,3,4)/p-1" ; chebi:inchikey "DUYAAUVXQSMXQP-UHFFFAOYSA-M" ; chebi:mass "75.11062" ; chebi:monoisotopicmass "74.99101" ; chebi:smiles "CC([S-])=O" ; oboInOwl:hasAlternativeId "CHEBI:15233", "CHEBI:26951" ; oboInOwl:hasDbXref "Beilstein:1848542", "Beilstein:3903387", "CAS:29632-72-2", "Gmelin:323277" ; oboInOwl:hasExactSynonym "ethanethioate", "thioacetate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Thioacetat" ; oboInOwl:id "CHEBI:30320" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "thioacetate" ; rdfs:subClassOf obo:CHEBI_35367, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_26952 ] . obo:CHEBI_30362 obo:IAO_0000115 "An alkane that is butane substituted by a methyl group at position 2." ; chebi:charge "0" ; chebi:formula "C5H12" ; chebi:inchi "InChI=1S/C5H12/c1-4-5(2)3/h5H,4H2,1-3H3" ; chebi:inchikey "QWTDNUCVQCZILF-UHFFFAOYSA-N" ; chebi:mass "72.14878" ; chebi:monoisotopicmass "72.09390" ; chebi:smiles "CCC(C)C" ; oboInOwl:hasDbXref "Beilstein:1730723", "CAS:78-78-4", "Gmelin:49318", "PMID:21481069", "PMID:23904008", "PMID:24833189", "PMID:24932627", "Reaxys:1730723", "Wikipedia:Isopentane" ; oboInOwl:hasExactSynonym "2-methylbutane", "isopentane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(CH3)2CH-CH2-CH3", "1,1,2-trimethylethane", "1,1-dimethylpropane", "R-601a", "dimethylethylmethane", "iso-C5H12", "iso-pentane", "isoamylhydride" ; oboInOwl:id "CHEBI:30362" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isopentane" ; rdfs:subClassOf obo:CHEBI_18310, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_30412 chebi:charge "+2" ; chebi:mass "0.00000" ; chebi:smiles "[*++]" ; oboInOwl:hasAlternativeId "CHEBI:23856", "CHEBI:4665" ; oboInOwl:hasDbXref "KEGG:C00572" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Divalent cation", "divalent inorganic cations", "monoatomic dications" ; oboInOwl:id "CHEBI:30412" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic dication" ; rdfs:subClassOf obo:CHEBI_23906 . obo:CHEBI_30413 obo:IAO_0000115 "A heme is any tetrapyrrolic chelate of iron." ; oboInOwl:hasAlternativeId "CHEBI:14386", "CHEBI:24491" ; oboInOwl:hasDbXref "COMe:MOL000025", "DrugBank:DB03014", "KEGG:C00032" ; oboInOwl:hasExactSynonym "heme", "hemes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Haem", "haem", "haeme", "hem", "hemos" ; oboInOwl:id "CHEBI:30413" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heme" ; rdfs:subClassOf obo:CHEBI_25216, obo:CHEBI_33892, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25212 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_26348 ] . obo:CHEBI_30488 chebi:charge "+1" ; chebi:formula "H3S" ; chebi:inchi "InChI=1S/H2S/h1H2/p+1" ; chebi:inchikey "RWSOTUBLDIXVET-UHFFFAOYSA-O" ; chebi:mass "35.08982" ; chebi:monoisotopicmass "34.99500" ; chebi:smiles "[H][S+]([H])[H]" ; oboInOwl:hasDbXref "CAS:18155-21-0", "Gmelin:307" ; oboInOwl:hasExactSynonym "sulfanium", "sulfonium", "trihydridosulfur(1+)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H3S(+)", "H3S+", "[SH3](+)", "sulphonium" ; oboInOwl:id "CHEBI:30488" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfonium" ; rdfs:subClassOf obo:CHEBI_26830, obo:CHEBI_33535, obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16136 ] . obo:CHEBI_30512 chebi:charge "0" ; chebi:formula "Ag" ; chebi:inchi "InChI=1S/Ag" ; chebi:inchikey "BQCADISMDOOEFD-UHFFFAOYSA-N" ; chebi:mass "107.86820" ; chebi:monoisotopicmass "106.90509" ; chebi:smiles "[Ag]" ; oboInOwl:hasDbXref "CAS:7440-22-4", "WebElements:Ag" ; oboInOwl:hasExactSynonym "silver" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "47Ag", "Ag", "Silber", "argent", "argentum", "plata", "silver" ; oboInOwl:id "CHEBI:30512" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "silver atom" ; rdfs:subClassOf obo:CHEBI_33366 . obo:CHEBI_30513 chebi:charge "0" ; chebi:formula "Sb" ; chebi:inchi "InChI=1S/Sb" ; chebi:inchikey "WATWJIUSRGPENY-UHFFFAOYSA-N" ; chebi:mass "121.76000" ; chebi:monoisotopicmass "120.90381" ; chebi:smiles "[Sb]" ; oboInOwl:hasDbXref "WebElements:Sb" ; oboInOwl:hasExactSynonym "antimony" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "51Sb", "Antimon", "Sb", "antimoine", "antimonio", "antimony", "stibium" ; oboInOwl:id "CHEBI:30513" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimony atom" ; rdfs:subClassOf obo:CHEBI_137980, obo:CHEBI_33300 . obo:CHEBI_30566 obo:IAO_0000115 "An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid." ; chebi:charge "-1" ; chebi:formula "C4H8NO2" ; chebi:inchi "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)/p-1" ; chebi:inchikey "BTCSSZJGUNDROE-UHFFFAOYSA-M" ; chebi:mass "102.11186" ; chebi:monoisotopicmass "102.05605" ; chebi:smiles "NCCCC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:11961", "CHEBI:20317" ; oboInOwl:hasDbXref "Beilstein:3536873", "Gmelin:559138", "KEGG:C00334", "PMID:12509893", "Reaxys:3536873" ; oboInOwl:hasExactSynonym "4-aminobutanoate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-Amino-butyrat", "4-Aminobutylate", "4-aminobutanoic acid ion (1-)", "4-aminobutyrate", "gamma-aminobutanoate", "gamma-aminobutyrate anion" ; oboInOwl:id "CHEBI:30566" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "gamma-aminobutyrate" ; rdfs:subClassOf obo:CHEBI_71666, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17968 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16865 ] . obo:CHEBI_30616 obo:IAO_0000115 "A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of ATP; major species present at pH 7.3." ; chebi:charge "-4" ; chebi:formula "C10H12N5O13P3" ; chebi:inchi "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/p-4/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "ZKHQWZAMYRWXGA-KQYNXXCUSA-J" ; chebi:mass "503.14946" ; chebi:monoisotopicmass "502.96664" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O" ; oboInOwl:hasDbXref "Beilstein:3581767", "Gmelin:342798" ; oboInOwl:hasExactSynonym "adenosine 5'-triphosphate(4-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ATP", "atp" ; oboInOwl:id "CHEBI:30616" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ATP(4-)" ; rdfs:subClassOf obo:CHEBI_61557, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_57299 ] . obo:CHEBI_30751 obo:IAO_0000115 "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects." ; chebi:charge "0" ; chebi:formula "CH2O2" ; chebi:inchi "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)" ; chebi:inchikey "BDAGIHXWWSANSR-UHFFFAOYSA-N" ; chebi:mass "46.02538" ; chebi:monoisotopicmass "46.00548" ; chebi:smiles "[H]C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:24082", "CHEBI:42460", "CHEBI:5145" ; oboInOwl:hasDbXref "BPDB:1749", "Beilstein:1209246", "CAS:64-18-6", "DrugBank:DB01942", "Gmelin:1008", "HMDB:HMDB0000142", "KEGG:C00058", "KNApSAcK:C00001182", "LIPID_MAPS_instance:LMFA01010040", "MetaCyc:FORMATE", "PDBeChem:FMT", "PMID:12591956", "PMID:14637377", "PMID:15811469", "PMID:16120414", "PMID:16185830", "PMID:16222862", "PMID:16230297", "PMID:16445901", "PMID:16465784", "PMID:18034701", "PMID:18397576", "PMID:22080171", "PMID:22280475", "PMID:22304812", "PMID:22385261", "PMID:22447125", "PMID:22483350", "PMID:22499553", "PMID:22540994", "PMID:22606986", "PMID:22622393", "PMID:3946945", "PMID:7361809", "Patent:CN101481304", "Reaxys:1209246", "Wikipedia:Formic_acid" ; oboInOwl:hasExactSynonym "FORMIC ACID", "Formic acid", "formic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Acide formique", "Ameisensaeure", "H-COOH", "HCO2H", "HCOOH", "Methanoic acid", "aminic acid", "bilorin", "formylic acid", "hydrogen carboxylic acid", "methoic acid" ; oboInOwl:id "CHEBI:30751" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "formic acid" ; rdfs:subClassOf obo:CHEBI_25384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25212 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33282 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48356 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_74783 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15740 ] . obo:CHEBI_30772 obo:IAO_0000115 "A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group." ; chebi:charge "0" ; chebi:formula "C4H8O2" ; chebi:inchi "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)" ; chebi:inchikey "FERIUCNNQQJTOY-UHFFFAOYSA-N" ; chebi:mass "88.10510" ; chebi:monoisotopicmass "88.05243" ; chebi:smiles "CCCC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:113450", "CHEBI:22948", "CHEBI:3234", "CHEBI:41208" ; oboInOwl:hasDbXref "Beilstein:906770", "CAS:107-92-6", "DrugBank:DB03568", "Gmelin:26242", "HMDB:HMDB0000039", "KEGG:C00246", "KNApSAcK:C00001180", "LIPID_MAPS_instance:LMFA01010004", "MetaCyc:BUTYRIC_ACID", "PDBeChem:BUA", "PMID:10736622", "PMID:10956204", "PMID:11201044", "PMID:11208715", "PMID:11238216", "PMID:11305323", "PMID:12068484", "PMID:13678314", "PMID:14962641", "PMID:1542095", "PMID:15809727", "PMID:15810631", "PMID:15938880", "PMID:19318247", "PMID:19366864", "PMID:19703412", "PMID:21699495", "PMID:22038864", "PMID:22194341", "PMID:22322557", "PMID:22339023", "PMID:22466881", "Reaxys:906770", "Wikipedia:Butyric_acid" ; oboInOwl:hasExactSynonym "Butyric acid", "butanoic acid", "butyric acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-butanoic acid", "1-butyric acid", "1-propanecarboxylic acid", "4:0", "BUTANOIC ACID", "Butanoate", "Butanoic acid", "Buttersaeure", "C4:0", "CH3-[CH2]2-COOH", "acide butanoique", "acide butyrique", "butanic acid", "butoic acid", "ethylacetic acid", "n-butanoic acid", "n-butyric acid", "propanecarboxylic acid", "propylformic acid" ; oboInOwl:id "CHEBI:30772" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "butyric acid" ; rdfs:subClassOf obo:CHEBI_140601, obo:CHEBI_39418, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_131604 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84087 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17968 ] . obo:CHEBI_30776 obo:IAO_0000115 "A C6, straight-chain saturated fatty acid." ; chebi:charge "0" ; chebi:formula "C6H12O2" ; chebi:inchi "InChI=1S/C6H12O2/c1-2-3-4-5-6(7)8/h2-5H2,1H3,(H,7,8)" ; chebi:inchikey "FUZZWVXGSFPDMH-UHFFFAOYSA-N" ; chebi:mass "116.15830" ; chebi:monoisotopicmass "116.08373" ; chebi:smiles "CCCCCC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:24571", "CHEBI:40213", "CHEBI:5702" ; oboInOwl:hasDbXref "Beilstein:773837", "CAS:142-62-1", "ECMDB:ECMDB21229", "Gmelin:185066", "HMDB:HMDB0000535", "KEGG:C01585", "KNApSAcK:C00001218", "LIPID_MAPS_instance:LMFA01010006", "MetaCyc:HEXANOATE", "PDBeChem:6NA", "PMID:10685018", "PMID:1556177", "PMID:24357269", "PMID:24924750", "Reaxys:773837", "Wikipedia:Hexanoic_acid", "YMDB:YMDB01424" ; oboInOwl:hasExactSynonym "HEXANOIC ACID", "Hexanoic acid", "hexanoic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-hexanoic acid", "1-pentanecarboxylic acid", "6:0", "C6:0", "CH3-[CH2]4-COOH", "Hexanoate", "Hexylic acid", "Pentanecarboxylic acid", "butylacetic acid", "caproic acid", "capronic acid", "hexoic acid", "n-Caproic acid", "n-hexanoic acid", "n-hexoic acid", "n-hexylic acid", "pentiformic acid", "pentylformic acid" ; oboInOwl:id "CHEBI:30776" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hexanoic acid" ; rdfs:subClassOf obo:CHEBI_39418, obo:CHEBI_59554, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17120 ] . obo:CHEBI_30879 obo:IAO_0000115 "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom." ; chebi:charge "0" ; chebi:formula "HOR" ; chebi:mass "17.007" ; chebi:monoisotopicmass "17.00274" ; chebi:smiles "O[*]" ; oboInOwl:hasAlternativeId "CHEBI:13804", "CHEBI:22288", "CHEBI:2553" ; oboInOwl:hasDbXref "KEGG:C00069" ; oboInOwl:hasExactSynonym "Alcohol", "alcohols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an alcohol" ; oboInOwl:id "CHEBI:30879" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alcohol" ; rdfs:subClassOf obo:CHEBI_33822 . obo:CHEBI_30953 obo:IAO_0000115 "A diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms." ; chebi:charge "0" ; chebi:formula "C4H4N2" ; chebi:inchi "InChI=1S/C4H4N2/c1-2-6-4-3-5-1/h1-4H" ; chebi:inchikey "KYQCOXFCLRTKLS-UHFFFAOYSA-N" ; chebi:mass "80.08804" ; chebi:monoisotopicmass "80.03745" ; chebi:smiles "c1cnccn1" ; oboInOwl:hasDbXref "Beilstein:103905", "CAS:290-37-9", "Gmelin:1733", "HMDB:HMDB0034176", "PMID:24964033", "Reaxys:103905", "Wikipedia:Pyrazine" ; oboInOwl:hasExactSynonym "pyrazine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,4-Diazin", "1,4-diazine", "Pyrazin", "p-diazine", "paradiazine", "pyz" ; oboInOwl:id "CHEBI:30953" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyrazine" ; rdfs:subClassOf obo:CHEBI_38314, obo:CHEBI_38627, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ] . obo:CHEBI_3098 obo:IAO_0000115 "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration." ; oboInOwl:hasDbXref "KEGG:C01558" ; oboInOwl:hasExactSynonym "Bile acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5beta-bile acid", "5beta-bile acids", "Bile salt", "Gallensaeure", "Gallensaeuren", "bile acids" ; oboInOwl:id "CHEBI:3098" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bile acid" ; rdfs:subClassOf obo:CHEBI_138366, obo:CHEBI_24663 . obo:CHEBI_30985 obo:IAO_0000115 "A bipyridine in which the two pyridine moieties are linked by a bond between positions C-4 and C-4'." ; chebi:charge "0" ; chebi:formula "C10H8N2" ; chebi:inchi "InChI=1S/C10H8N2/c1-5-11-6-2-9(1)10-3-7-12-8-4-10/h1-8H" ; chebi:inchikey "MWVTWFVJZLCBMC-UHFFFAOYSA-N" ; chebi:mass "156.18400" ; chebi:monoisotopicmass "156.06875" ; chebi:smiles "c1cc(ccn1)-c1ccncc1" ; oboInOwl:hasDbXref "Beilstein:113176", "CAS:553-26-4", "Gmelin:3759", "PMID:24022647", "PMID:24358992", "PMID:24446585", "Reaxys:113176", "Wikipedia:4,4%27-Bipyridine" ; oboInOwl:hasExactSynonym "4,4'-bipyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4,4'-bipyridyl", "4,4'-bpy", "4,4'-dipyridine", "4,4'-dipyridyl", "4,4-Bipyridin", "4-(4-pyridyl)pyridine", "gamma,gamma'-bipyridyl", "gamma,gamma'-dipyridyl" ; oboInOwl:id "CHEBI:30985" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "4,4'-bipyridine" ; rdfs:subClassOf obo:CHEBI_35545 . obo:CHEBI_31206 obo:IAO_0000115 "An inorganic chloride having ammonium as the counterion." ; chebi:charge "0" ; chebi:formula "Cl.H4N", "ClH4N" ; chebi:inchi "InChI=1S/ClH.H3N/h1H;1H3" ; chebi:inchikey "NLXLAEXVIDQMFP-UHFFFAOYSA-N" ; chebi:mass "53.49120" ; chebi:monoisotopicmass "53.00323" ; chebi:smiles "[Cl-].[H][N+]([H])([H])[H]" ; oboInOwl:hasDbXref "CAS:12125-02-9", "Gmelin:10120", "KEGG:C12538", "KEGG:D01139", "Wikipedia:Ammonium_Chloride" ; oboInOwl:hasExactSynonym "Ammonium chloride", "ammonium chloride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ammoniumchlorid", "NH4Cl", "[NH4]Cl", "azanium chloride" ; oboInOwl:id "CHEBI:31206" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ammonium chloride" ; rdfs:subClassOf obo:CHEBI_36093, obo:CHEBI_47704, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_173084 ] . obo:CHEBI_32442 obo:IAO_0000115 "The L-enantiomer of cysteinate(1-)." ; chebi:charge "-1" ; chebi:formula "C3H6NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-M" ; chebi:mass "120.15128" ; chebi:monoisotopicmass "120.01247" ; chebi:smiles "N[C@@H](CS)C([O-])=O" ; oboInOwl:hasDbXref "Beilstein:4128886", "Gmelin:325857", "Reaxys:4128886" ; oboInOwl:hasExactSynonym "L-cysteinate(1-)", "hydrogen L-cysteinate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R)-2-amino-3-mercaptopropanoate", "(2R)-2-amino-3-sulfanylpropanoate", "L-cysteine anion", "L-cysteine monoanion" ; oboInOwl:id "CHEBI:32442" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-cysteinate(1-)" ; rdfs:subClassOf obo:CHEBI_32456, obo:CHEBI_59814, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32443 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17561 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35235 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32449 ] . obo:CHEBI_32443 obo:IAO_0000115 "The L-enantiomer of cysteinate(2-)." ; chebi:charge "-2" ; chebi:formula "C3H5NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-L" ; chebi:mass "119.14334" ; chebi:monoisotopicmass "119.00520" ; chebi:smiles "N[C@@H](C[S-])C([O-])=O" ; oboInOwl:hasDbXref "Beilstein:5921923", "Gmelin:325856", "Reaxys:5921923" ; oboInOwl:hasExactSynonym "L-cysteinate", "L-cysteinate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R)-2-amino-3-sulfidopropanoate", "L-cysteine dianion" ; oboInOwl:id "CHEBI:32443" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-cysteinate(2-)" ; rdfs:subClassOf obo:CHEBI_32457, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32442 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32450 ] . obo:CHEBI_32445 obo:IAO_0000115 "The L-enantiomer of cysteinium." ; chebi:charge "+1" ; chebi:formula "C3H8NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-O" ; chebi:mass "122.16716" ; chebi:monoisotopicmass "122.02703" ; chebi:smiles "[NH3+][C@@H](CS)C(O)=O" ; oboInOwl:hasDbXref "Gmelin:325860" ; oboInOwl:hasExactSynonym "L-cysteinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(1R)-1-carboxy-2-mercaptoethanaminium", "(1R)-1-carboxy-2-sulfanylethanaminium", "L-cysteine cation", "L-cysteinium(1+)" ; oboInOwl:id "CHEBI:32445" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-cysteinium" ; rdfs:subClassOf obo:CHEBI_32458, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17561 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_35235 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32451 ] . obo:CHEBI_32449 obo:IAO_0000115 "The D-enantiomer of cysteinate(1-)." ; chebi:charge "-1" ; chebi:formula "C3H6NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-M" ; chebi:mass "120.15128" ; chebi:monoisotopicmass "120.01247" ; chebi:smiles "N[C@H](CS)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:1006156" ; oboInOwl:hasExactSynonym "D-cysteinate(1-)", "hydrogen D-cysteinate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2S)-2-amino-3-mercaptopropanoate", "(2S)-2-amino-3-sulfanylpropanoate", "D-cysteine monoanion" ; oboInOwl:id "CHEBI:32449" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-cysteinate(1-)" ; rdfs:subClassOf obo:CHEBI_32456, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32450 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16375 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35236 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32442 ] . obo:CHEBI_32450 obo:IAO_0000115 "The D-enantiomer of cysteinate(2-)." ; chebi:charge "-2" ; chebi:formula "C3H5NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-L" ; chebi:mass "119.14334" ; chebi:monoisotopicmass "119.00520" ; chebi:smiles "N[C@H](C[S-])C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:1342792" ; oboInOwl:hasExactSynonym "D-cysteinate", "D-cysteinate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2S)-2-amino-3-sulfidopropanoate", "D-cysteine dianion" ; oboInOwl:id "CHEBI:32450" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-cysteinate(2-)" ; rdfs:subClassOf obo:CHEBI_32457, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32449 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32443 ] . obo:CHEBI_32451 obo:IAO_0000115 "The D-enantiomer of cysteinium." ; chebi:charge "+1" ; chebi:formula "C3H8NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-O" ; chebi:mass "122.16716" ; chebi:monoisotopicmass "122.02703" ; chebi:smiles "[NH3+][C@H](CS)C(O)=O" ; oboInOwl:hasDbXref "Gmelin:363237" ; oboInOwl:hasExactSynonym "D-cysteinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(1S)-1-carboxy-2-mercaptoethanaminium", "(1S)-1-carboxy-2-sulfanylethanaminium", "D-cysteine cation" ; oboInOwl:id "CHEBI:32451" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-cysteinium" ; rdfs:subClassOf obo:CHEBI_32458, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16375 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_35236 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32445 ] . obo:CHEBI_32456 obo:IAO_0000115 "A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group." ; chebi:charge "-1" ; chebi:formula "C3H6NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-M" ; chebi:mass "120.15128" ; chebi:monoisotopicmass "120.01247" ; chebi:smiles "NC(CS)C([O-])=O" ; oboInOwl:hasDbXref "Beilstein:4128885", "Gmelin:363235", "Reaxys:4128885" ; oboInOwl:hasExactSynonym "cysteinate(1-)", "hydrogen cysteinate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-amino-3-mercaptopropanoate", "2-amino-3-sulfanylpropanoate", "cys(-)", "cysteine monoanion" ; oboInOwl:id "CHEBI:32456" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cysteinate(1-)" ; rdfs:subClassOf obo:CHEBI_33558, obo:CHEBI_63470, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32457 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_15356 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35237 ] . obo:CHEBI_32457 chebi:charge "-2" ; chebi:formula "C3H5NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-L" ; chebi:mass "119.14334" ; chebi:monoisotopicmass "119.00520" ; chebi:smiles "NC(C[S-])C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:49990" ; oboInOwl:hasExactSynonym "cysteinate", "cysteinate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-amino-3-sulfidopropanoate", "cysteine dianion" ; oboInOwl:id "CHEBI:32457" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cysteinate(2-)" ; rdfs:subClassOf obo:CHEBI_33558, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32456 ] . obo:CHEBI_32458 chebi:charge "+1" ; chebi:formula "C3H8NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-O" ; chebi:mass "122.16716" ; chebi:monoisotopicmass "122.02703" ; chebi:smiles "[NH3+]C(CS)C(O)=O" ; oboInOwl:hasDbXref "Gmelin:325859" ; oboInOwl:hasExactSynonym "1-carboxy-2-sulfanylethanaminium", "cysteinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-carboxy-2-mercaptoethanaminium", "H2cys(+)", "cysteine cation" ; oboInOwl:id "CHEBI:32458" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cysteinium" ; rdfs:subClassOf obo:CHEBI_33719, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15356 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_35237 ] . obo:CHEBI_32563 obo:IAO_0000115 "An alpha-amino-acid anion that is the conjugate base of lysine, arising from deprotonation of the carboxy group." ; chebi:charge "-1" ; chebi:formula "C6H13N2O2" ; chebi:inchi "InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p-1" ; chebi:inchikey "KDXKERNSBIXSRK-UHFFFAOYSA-M" ; chebi:mass "145.17970" ; chebi:monoisotopicmass "145.09825" ; chebi:smiles "NCCCCC(N)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:815095" ; oboInOwl:hasExactSynonym "lysinate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,6-diaminohexanoate", "lys(-)", "lysinate(1-)", "lysine anion" ; oboInOwl:id "CHEBI:32563" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "lysinate" ; rdfs:subClassOf obo:CHEBI_33558, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_25094 ] . obo:CHEBI_32564 obo:IAO_0000115 "An alpha-amino-acid cation that is the conjugate acid of lysine, having two cationic amino groups and an anionic carboxy group." ; chebi:charge "+1" ; chebi:formula "C6H15N2O2" ; chebi:inchi "InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+1" ; chebi:inchikey "KDXKERNSBIXSRK-UHFFFAOYSA-O" ; chebi:mass "147.19558" ; chebi:monoisotopicmass "147.11280" ; chebi:smiles "[NH3+]CCCCC([NH3+])C([O-])=O" ; oboInOwl:hasExactSynonym "lysinium", "lysinium(1+)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,6-diammoniohexanoate", "lysine monocation" ; oboInOwl:id "CHEBI:32564" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "lysinium(1+)" ; rdfs:subClassOf obo:CHEBI_33719, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_25094 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32565 ] . obo:CHEBI_32565 obo:IAO_0000115 "An alpha-amino-acid cation obtained by protonation of both amino groups of lysine." ; chebi:charge "+2" ; chebi:formula "C6H16N2O2" ; chebi:inchi "InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+2" ; chebi:inchikey "KDXKERNSBIXSRK-UHFFFAOYSA-P" ; chebi:mass "148.20352" ; chebi:monoisotopicmass "148.12008" ; chebi:smiles "[NH3+]CCCCC([NH3+])C(O)=O" ; oboInOwl:hasExactSynonym "lysinediium", "lysinium(2+)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-carboxypentane-1,5-diaminium", "lysine dication" ; oboInOwl:id "CHEBI:32565" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "lysinium(2+)" ; rdfs:subClassOf obo:CHEBI_33719, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32564 ] . obo:CHEBI_32876 obo:IAO_0000115 "A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups." ; chebi:charge "0" ; chebi:formula "NR3" ; chebi:mass "14.00670" ; chebi:monoisotopicmass "14.00307" ; chebi:smiles "[*]N([*])[*]" ; oboInOwl:hasAlternativeId "CHEBI:26879", "CHEBI:9458" ; oboInOwl:hasDbXref "KEGG:C02196" ; oboInOwl:hasExactSynonym "Tertiary amine", "tertiary amines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "R3N", "tertiaeres Amin" ; oboInOwl:id "CHEBI:32876" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tertiary amine" ; rdfs:subClassOf obo:CHEBI_32952, obo:CHEBI_50996 . obo:CHEBI_32877 obo:IAO_0000115 "A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group." ; chebi:charge "0" ; chebi:formula "H2NR" ; chebi:mass "16.02260" ; chebi:monoisotopicmass "16.01872" ; chebi:smiles "N[*]" ; oboInOwl:hasAlternativeId "CHEBI:26263", "CHEBI:26265", "CHEBI:8407", "CHEBI:8409" ; oboInOwl:hasDbXref "KEGG:C00375", "KEGG:C00893", "KEGG:C02580" ; oboInOwl:hasExactSynonym "Primary amine", "primary amines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Primary monoamine", "R-NH2", "RCH2NH2", "primaeres Amin" ; oboInOwl:id "CHEBI:32877" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "primary amine" ; rdfs:subClassOf obo:CHEBI_32952, obo:CHEBI_50994 . obo:CHEBI_32952 obo:IAO_0000115 "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." ; oboInOwl:hasAlternativeId "CHEBI:13814", "CHEBI:22474", "CHEBI:2641" ; oboInOwl:hasDbXref "KEGG:C00706" ; oboInOwl:hasExactSynonym "Amine", "amines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Amin", "Substituted amine", "an amine" ; oboInOwl:id "CHEBI:32952" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amine" ; rdfs:subClassOf obo:CHEBI_50047 . obo:CHEBI_32954 chebi:charge "0" ; chebi:formula "C2H3NaO2" ; chebi:inchi "InChI=1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1" ; chebi:inchikey "VMHLLURERBWHNL-UHFFFAOYSA-M" ; chebi:mass "82.03379" ; chebi:monoisotopicmass "82.00307" ; chebi:smiles "[Na+].CC([O-])=O" ; oboInOwl:hasDbXref "Beilstein:3595639", "CAS:127-09-3", "Gmelin:20502", "Wikipedia:Sodium_Acetate" ; oboInOwl:hasExactSynonym "sodium acetate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Natriumazetat", "acetic acid, sodium salt", "anhydrous sodium acetate", "sodium acetate anhydrous" ; oboInOwl:id "CHEBI:32954" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sodium acetate" ; rdfs:subClassOf obo:CHEBI_38700, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_30089 ] . obo:CHEBI_32988 obo:IAO_0000115 "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; oboInOwl:hasAlternativeId "CHEBI:22473", "CHEBI:2633" ; oboInOwl:hasDbXref "KEGG:C00241" ; oboInOwl:hasExactSynonym "Amide", "amides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:32988" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amide" ; rdfs:subClassOf obo:CHEBI_51143 . obo:CHEBI_33083 obo:IAO_0000115 "An ortho- and peri-fused polycyclic arene consisting of a naphthalene and benzene unit connected by a five-membered ring." ; chebi:charge "0" ; chebi:formula "C16H10" ; chebi:inchi "InChI=1S/C16H10/c1-2-8-13-12(7-1)14-9-3-5-11-6-4-10-15(13)16(11)14/h1-10H" ; chebi:inchikey "GVEPBJHOBDJJJI-UHFFFAOYSA-N" ; chebi:mass "202.25060" ; chebi:monoisotopicmass "202.07825" ; chebi:smiles "c1ccc-2c(c1)-c1cccc3cccc-2c13" ; oboInOwl:hasDbXref "Beilstein:1907918", "CAS:206-44-0", "Gmelin:262216", "KEGG:C19425", "MetaCyc:CPD-15564", "PMID:15278918", "PMID:17258277", "PMID:23943046", "PMID:24151025", "Reaxys:1907918", "Wikipedia:Fluoranthene" ; oboInOwl:hasExactSynonym "fluoranthene" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "benzo[jk]fluorene" ; oboInOwl:id "CHEBI:33083" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluoranthene" ; rdfs:subClassOf obo:CHEBI_35300 . obo:CHEBI_33216 obo:IAO_0000115 "A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups." ; chebi:charge "0" ; chebi:formula "C15H16O2" ; chebi:inchi "InChI=1S/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3" ; chebi:inchikey "IISBACLAFKSPIT-UHFFFAOYSA-N" ; chebi:mass "228.291" ; chebi:monoisotopicmass "228.11503" ; chebi:smiles "CC(C)(C1=CC=C(O)C=C1)C1=CC=C(O)C=C1" ; oboInOwl:hasAlternativeId "CHEBI:22900", "CHEBI:31295", "CHEBI:47094" ; oboInOwl:hasDbXref "CAS:80-05-7", "DrugBank:DB06973", "HMDB:HMDB0032133", "KEGG:C13624", "LINCS:LSM-37080", "PDBeChem:2OH", "PMID:10593191", "PMID:11361040", "PMID:12860292", "PMID:15936980", "PMID:16904728", "PMID:24471646", "PMID:25042713", "PMID:25148994", "PMID:25524584", "PMID:25569640", "PMID:25637671", "PMID:25663485", "Reaxys:1107700", "UM-BBD_compID:c0764", "Wikipedia:Bisphenol_A" ; oboInOwl:hasExactSynonym "4,4'-(propane-2,2-diyl)diphenol", "Bisphenol A", "bisphenol A" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2, 2-Bis(4-hydroxyphenyl)propane", "2,2-Bis(4'-hydroxyphenyl)propane", "2,2-Bis(4-Hydroxyphenyl)propane", "2,2-Bis(p-hydroxyphenyl)propane", "2,2-Di(4-hydroxyphenyl)propane", "2,2-Di(4-phenylol)propane", "4,4'-(1-Methylethane-1,1-diyl)diphenol", "4,4'-(1-Methylethylidene)bisphenol", "4,4'-(Propane-2,2-diyl)diphenol", "4,4'-Bisphenol A", "4,4'-Isopropylidenediphenol", "BPA", "Dianin's compound", "bisphenol-A" ; oboInOwl:id "CHEBI:33216" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bisphenol A" ; rdfs:subClassOf obo:CHEBI_22901, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76988 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ] . obo:CHEBI_33232 obo:IAO_0000115 "Intended use of the molecular entity or part thereof by humans." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33232" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "application" ; rdfs:subClassOf obo:BFO_0000023, obo:CHEBI_50906 . obo:CHEBI_33233 obo:IAO_0000115 "A particle not known to have substructure." ; oboInOwl:hasExactSynonym "elementary particle" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "elementary particles" ; oboInOwl:id "CHEBI:33233" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fundamental particle" ; rdfs:subClassOf obo:CHEBI_36342 . obo:CHEBI_33238 obo:IAO_0000115 "A monoatomic entity is a molecular entity consisting of a single atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic entity", "monoatomic entities" ; oboInOwl:id "CHEBI:33238" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic entity" ; rdfs:subClassOf obo:CHEBI_33259 . obo:CHEBI_33240 obo:IAO_0000115 "An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands)." ; oboInOwl:hasExactSynonym "coordination entities", "coordination entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "coordination compounds" ; oboInOwl:id "CHEBI:33240" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "coordination entity" ; rdfs:subClassOf obo:CHEBI_37577 . obo:CHEBI_33241 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoacid derivatives" ; oboInOwl:id "CHEBI:33241" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxoacid derivative" ; rdfs:subClassOf obo:CHEBI_37577, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_24833 ] . obo:CHEBI_33242 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic hydrides" ; oboInOwl:id "CHEBI:33242" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic hydride" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_33692 . obo:CHEBI_33245 obo:IAO_0000115 "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic fundamental parents", "organic parent hydrides" ; oboInOwl:id "CHEBI:33245" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic fundamental parent" ; rdfs:subClassOf obo:CHEBI_37175, obo:CHEBI_50860 . obo:CHEBI_33246 obo:IAO_0000115 "Any substituent group which does not contain carbon." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic groups" ; oboInOwl:id "CHEBI:33246" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic group" ; rdfs:subClassOf obo:CHEBI_24433 . obo:CHEBI_33247 obo:IAO_0000115 "Any substituent group or skeleton containing carbon." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic groups" ; oboInOwl:id "CHEBI:33247" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic group" ; rdfs:subClassOf obo:CHEBI_24433, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_50860 ] . obo:CHEBI_33248 obo:IAO_0000115 "A univalent group formed by removing a hydrogen atom from a hydrocarbon." ; oboInOwl:hasExactSynonym "hydrocarbyl group", "hydrocarbyl groups" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "groupe hydrocarbyle", "grupo hidrocarbilo", "grupos hidrocarbilo" ; oboInOwl:id "CHEBI:33248" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrocarbyl group" ; rdfs:subClassOf obo:CHEBI_33249, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_24632 ] . obo:CHEBI_33249 obo:IAO_0000115 "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." ; oboInOwl:hasExactSynonym "organyl group", "organyl groups" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "groupe organyle", "grupo organilo", "grupos organilo" ; oboInOwl:id "CHEBI:33249" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organyl group" ; rdfs:subClassOf obo:CHEBI_51447 . obo:CHEBI_33250 obo:IAO_0000115 "A chemical entity constituting the smallest component of an element having the chemical properties of the element." ; oboInOwl:hasAlternativeId "CHEBI:22671", "CHEBI:23907" ; oboInOwl:hasExactSynonym "atom" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atome", "atomo", "atoms", "atomus", "element", "elements" ; oboInOwl:id "CHEBI:33250" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "atom" ; rdfs:subClassOf obo:CHEBI_24431, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_10545 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33252 ] . obo:CHEBI_33252 obo:IAO_0000115 "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." ; oboInOwl:hasExactSynonym "nucleus" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Atomkern", "Kern", "noyau", "noyau atomique", "nuclei", "nucleo", "nucleo atomico", "nucleus atomi" ; oboInOwl:id "CHEBI:33252" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "atomic nucleus" ; rdfs:subClassOf obo:CHEBI_36347, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33253 ] . obo:CHEBI_33253 obo:IAO_0000115 "Heavy nuclear particle: proton or neutron." ; oboInOwl:hasExactSynonym "nucleon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Nukleon", "Nukleonen", "nucleons" ; oboInOwl:id "CHEBI:33253" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleon" ; rdfs:subClassOf obo:CHEBI_36339, obo:CHEBI_36347 . obo:CHEBI_33256 obo:IAO_0000115 "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; oboInOwl:hasExactSynonym "primary amide", "primary amides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33256" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "primary amide" ; rdfs:subClassOf obo:CHEBI_32988 . obo:CHEBI_33257 obo:IAO_0000115 "A derivative of two oxoacids RkE(=O)l(OH)m (l =/= 0) in which two acyl groups are attached to the amino or substituted amino group." ; oboInOwl:hasExactSynonym "secondary amide", "secondary amides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33257" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "secondary amide" ; rdfs:subClassOf obo:CHEBI_32988 . obo:CHEBI_33259 obo:IAO_0000115 "A molecular entity all atoms of which have the same atomic number." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "homoatomic entity", "homoatomic molecular entities", "homoatomic molecular entity" ; oboInOwl:id "CHEBI:33259" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental molecular entity" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_33261 obo:IAO_0000115 "An organosulfur compound is a compound containing at least one carbon-sulfur bond." ; oboInOwl:hasAlternativeId "CHEBI:23010", "CHEBI:25714" ; oboInOwl:hasDbXref "Wikipedia:Organosulfur_compounds" ; oboInOwl:hasExactSynonym "organosulfur compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organosulfur compounds" ; oboInOwl:id "CHEBI:33261" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organosulfur compound" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_36962 . obo:CHEBI_33262 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33262" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental oxygen" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_25806, obo:CHEBI_33259 . obo:CHEBI_33263 chebi:charge "0" ; chebi:formula "O2" ; chebi:mass "31.999" ; chebi:monoisotopicmass "31.98983" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33263" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diatomic oxygen" ; rdfs:subClassOf obo:CHEBI_33262 . obo:CHEBI_33273 obo:IAO_0000115 "An anion consisting of more than one atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic anions" ; oboInOwl:id "CHEBI:33273" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polyatomic anion" ; rdfs:subClassOf obo:CHEBI_22563, obo:CHEBI_36358 . obo:CHEBI_33280 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chemical messenger" ; oboInOwl:id "CHEBI:33280" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "molecular messenger" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_33281 obo:IAO_0000115 "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." ; oboInOwl:hasAlternativeId "CHEBI:22582" ; oboInOwl:hasDbXref "PMID:12964249", "PMID:22117953", "PMID:22439833", "PMID:22849268", "PMID:22849276", "PMID:22958833" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Antibiotika", "Antibiotikum", "antibiotic", "antibiotics", "antibiotique", "antimicrobial", "antimicrobial agents", "antimicrobials", "microbicide", "microbicides" ; oboInOwl:id "CHEBI:33281" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimicrobial agent" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_33282 obo:IAO_0000115 "A substance (or active part thereof) that kills or slows the growth of bacteria." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antibacterial agents", "antibacterials", "bactericide", "bactericides" ; oboInOwl:id "CHEBI:33282" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antibacterial agent" ; rdfs:subClassOf obo:CHEBI_33281 . obo:CHEBI_33284 obo:IAO_0000115 "A nutrient is a food component that an organism uses to survive and grow." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nutrients" ; oboInOwl:id "CHEBI:33284" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nutrient" ; rdfs:subClassOf obo:CHEBI_78295 . obo:CHEBI_33285 obo:IAO_0000115 "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heteroorganic entities", "organoelement compounds" ; oboInOwl:id "CHEBI:33285" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heteroorganic entity" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_33286 obo:IAO_0000115 "An agrochemical is a substance that is used in agriculture or horticulture." ; oboInOwl:hasDbXref "Wikipedia:Agrochemical" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agrichemical", "agrichemicals", "agricultural chemicals", "agrochemicals" ; oboInOwl:id "CHEBI:33286" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "agrochemical" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_33287 obo:IAO_0000115 "A fertilizer is any substance that is added to soil or water to assist the growth of plants." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fertiliser", "fertilizers" ; oboInOwl:id "CHEBI:33287" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fertilizer" ; rdfs:subClassOf obo:CHEBI_33286 . obo:CHEBI_33290 obo:IAO_0000115 "A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food material", "food materials", "food role", "foods", "foodstuff", "foodstuffs" ; oboInOwl:id "CHEBI:33290" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "food" ; rdfs:subClassOf obo:CHEBI_52211, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_78295 ] . obo:CHEBI_33292 obo:IAO_0000115 "An energy-rich substance that can be transformed with release of usable energy." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33292" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fuel" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_33296 obo:IAO_0000115 "A molecular entity containing one or more atoms of an alkali metal." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkali metal molecular entities" ; oboInOwl:id "CHEBI:33296" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkali metal molecular entity" ; rdfs:subClassOf obo:CHEBI_33674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22314 ] . obo:CHEBI_33299 obo:IAO_0000115 "An alkaline earth molecular entity is a molecular entity containing one or more atoms of an alkaline earth metal." ; oboInOwl:hasExactSynonym "alkaline earth molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkaline earth compounds", "alkaline earth molecular entities", "alkaline-earth compounds" ; oboInOwl:id "CHEBI:33299" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkaline earth molecular entity" ; rdfs:subClassOf obo:CHEBI_33674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22313 ] . obo:CHEBI_33300 obo:IAO_0000115 "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." ; oboInOwl:hasExactSynonym "pnictogens" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "group 15 elements", "group V elements", "nitrogenoideos", "nitrogenoides", "pnictogene", "pnictogenes" ; oboInOwl:id "CHEBI:33300" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pnictogen" ; rdfs:subClassOf obo:CHEBI_33560 . obo:CHEBI_33302 obo:IAO_0000115 "A p-block molecular entity containing any pnictogen." ; oboInOwl:hasExactSynonym "pnictogen molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pnictogen molecular entities" ; oboInOwl:id "CHEBI:33302" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pnictogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33300 ] . obo:CHEBI_33303 obo:IAO_0000115 "Any p-block element belonging to the group 16 family of the periodic table." ; oboInOwl:hasDbXref "PMID:17084588" ; oboInOwl:hasExactSynonym "chalcogen", "chalcogens" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Chalkogen", "Chalkogene", "anfigeno", "anfigenos", "calcogeno", "calcogenos", "chalcogene", "chalcogenes", "group 16 elements", "group VI elements" ; oboInOwl:id "CHEBI:33303" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chalcogen" ; rdfs:subClassOf obo:CHEBI_33560 . obo:CHEBI_33304 obo:IAO_0000115 "Any p-block molecular entity containing a chalcogen." ; oboInOwl:hasExactSynonym "chalcogen molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcogen compounds", "chalcogen molecular entities" ; oboInOwl:id "CHEBI:33304" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chalcogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33303 ] . obo:CHEBI_33306 oboInOwl:hasExactSynonym "group 14 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon group element", "carbon group elements", "carbonoides", "cristallogene", "cristallogenes", "group IV elements" ; oboInOwl:id "CHEBI:33306" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbon group element atom" ; rdfs:subClassOf obo:CHEBI_33560 . obo:CHEBI_33307 obo:IAO_0000115 "An organic acid in which one or both oxygens of a carboxy group have been replaced by divalent sulfur." ; oboInOwl:hasExactSynonym "carbothioic acids", "thiocarboxylic acid", "thiocarboxylic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "thiocarboxylic acids" ; oboInOwl:id "CHEBI:33307" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "thiocarboxylic acid" ; rdfs:subClassOf obo:CHEBI_33261, obo:CHEBI_64709 . obo:CHEBI_33308 obo:IAO_0000115 "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." ; chebi:charge "0" ; chebi:formula "CO2R2" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[*]C(=O)O[*]" ; oboInOwl:hasAlternativeId "CHEBI:13204", "CHEBI:23028", "CHEBI:3408" ; oboInOwl:hasDbXref "KEGG:C02391", "Wikipedia:Ester" ; oboInOwl:hasExactSynonym "Carboxylic ester", "carboxylic esters" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a carboxylic ester", "carboxylic acid esters" ; oboInOwl:id "CHEBI:33308" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carboxylic ester" ; rdfs:subClassOf obo:CHEBI_35701, obo:CHEBI_36586 . obo:CHEBI_33318 obo:IAO_0000115 "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." ; oboInOwl:hasExactSynonym "main group elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Hauptgruppenelement", "Hauptgruppenelemente", "main group element" ; oboInOwl:id "CHEBI:33318" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "main group element atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_33340 oboInOwl:hasExactSynonym "group 12 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "zinc group element", "zinc group elements" ; oboInOwl:id "CHEBI:33340" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "zinc group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33352 oboInOwl:hasExactSynonym "group 7 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "manganese group element", "manganese group elements" ; oboInOwl:id "CHEBI:33352" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "manganese group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33356 oboInOwl:hasExactSynonym "group 8 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iron group element", "iron group elements" ; oboInOwl:id "CHEBI:33356" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iron group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33358 oboInOwl:hasExactSynonym "group 9 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cobalt group element", "cobalt group elements" ; oboInOwl:id "CHEBI:33358" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cobalt group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33362 oboInOwl:hasExactSynonym "group 10 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nickel group element", "nickel group elements" ; oboInOwl:id "CHEBI:33362" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nickel group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33366 oboInOwl:hasExactSynonym "group 11 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "coinage metals", "copper group element", "copper group elements" ; oboInOwl:id "CHEBI:33366" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "copper group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33402 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoacids of sulfur", "sulfur oxoacids" ; oboInOwl:id "CHEBI:33402" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur oxoacid" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_33484 . obo:CHEBI_33405 obo:IAO_0000115 "A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ; oboInOwl:hasExactSynonym "hydracid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydracids" ; oboInOwl:id "CHEBI:33405" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydracid" ; rdfs:subClassOf obo:CHEBI_33608, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39141 ] . obo:CHEBI_33408 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pnictogen oxoacids" ; oboInOwl:id "CHEBI:33408" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pnictogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24833, obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138103 ] . obo:CHEBI_33424 oboInOwl:hasExactSynonym "sulfur oxoacid derivative" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfur oxoacid derivatives" ; oboInOwl:id "CHEBI:33424" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur oxoacid derivative" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_33241 . obo:CHEBI_33425 oboInOwl:hasExactSynonym "halogen oxoacid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogen oxoacids" ; oboInOwl:id "CHEBI:33425" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24471, obo:CHEBI_24833, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138103 ] . obo:CHEBI_33426 oboInOwl:hasExactSynonym "chlorine oxoacid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chlorine oxoacids" ; oboInOwl:id "CHEBI:33426" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chlorine oxoacid" ; rdfs:subClassOf obo:CHEBI_23117, obo:CHEBI_33425, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33437 ] . obo:CHEBI_33429 chebi:charge "-1" ; chebi:mass "0.00000" ; chebi:smiles "[*-]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic monoanions" ; oboInOwl:id "CHEBI:33429" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic monoanion" ; rdfs:subClassOf obo:CHEBI_23905, obo:CHEBI_36830 . obo:CHEBI_33431 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33431" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental chlorine" ; rdfs:subClassOf obo:CHEBI_23117, obo:CHEBI_33434 . obo:CHEBI_33432 chebi:charge "0" ; chebi:formula "Cl" ; chebi:mass "35.453" ; chebi:monoisotopicmass "34.96885" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic chlorine" ; oboInOwl:id "CHEBI:33432" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic chlorine" ; rdfs:subClassOf obo:CHEBI_33431, obo:CHEBI_33433 . obo:CHEBI_33433 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic halogens" ; oboInOwl:id "CHEBI:33433" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic halogen" ; rdfs:subClassOf obo:CHEBI_33238 . obo:CHEBI_33434 oboInOwl:hasExactSynonym "elemental halogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "elemental halogens" ; oboInOwl:id "CHEBI:33434" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental halogen" ; rdfs:subClassOf obo:CHEBI_33259 . obo:CHEBI_33437 oboInOwl:hasExactSynonym "chlorine oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chlorine oxoanions" ; oboInOwl:id "CHEBI:33437" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chlorine oxoanion" ; rdfs:subClassOf obo:CHEBI_23117, obo:CHEBI_33443, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33426 ] . obo:CHEBI_33443 oboInOwl:hasExactSynonym "halogen oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogen oxoanions" ; oboInOwl:id "CHEBI:33443" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halogen oxoanion" ; rdfs:subClassOf obo:CHEBI_24471, obo:CHEBI_24834, obo:CHEBI_35406 . obo:CHEBI_33447 obo:IAO_0000115 "Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid." ; oboInOwl:hasAlternativeId "CHEBI:15132", "CHEBI:25406", "CHEBI:26086", "CHEBI:9320" ; oboInOwl:hasDbXref "KEGG:C00934", "PMID:18186488" ; oboInOwl:hasExactSynonym "phospho sugar" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monosaccharide phosphates", "phospho sugars", "phosphorylated sugar", "phosphorylated sugars", "phosphosugar", "phosphosugars" ; oboInOwl:id "CHEBI:33447" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phospho sugar" ; rdfs:subClassOf obo:CHEBI_26816, obo:CHEBI_63367 . obo:CHEBI_33457 obo:IAO_0000115 "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." ; oboInOwl:hasExactSynonym "phosphorus oxoacid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Oxosaeure des Phosphors", "oxoacids of phosphorus", "phosphorus oxoacids" ; oboInOwl:id "CHEBI:33457" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphorus oxoacid" ; rdfs:subClassOf obo:CHEBI_33408, obo:CHEBI_36360 . obo:CHEBI_33459 oboInOwl:hasExactSynonym "pnictogen oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pnictogen oxoanions" ; oboInOwl:id "CHEBI:33459" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pnictogen oxoanion" ; rdfs:subClassOf obo:CHEBI_33302, obo:CHEBI_35406 . obo:CHEBI_33461 oboInOwl:hasExactSynonym "phosphorus oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoanions of phosphorus", "phosphorus oxoanions" ; oboInOwl:id "CHEBI:33461" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphorus oxoanion" ; rdfs:subClassOf obo:CHEBI_24834, obo:CHEBI_26082, obo:CHEBI_33459 . obo:CHEBI_33482 oboInOwl:hasExactSynonym "sulfur oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoanions of sulfur", "sulfur oxoanions" ; oboInOwl:id "CHEBI:33482" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur oxoanion" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_33485 . obo:CHEBI_33484 oboInOwl:hasExactSynonym "chalcogen oxoacid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcogen oxoacids" ; oboInOwl:id "CHEBI:33484" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chalcogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24833, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138103 ] . obo:CHEBI_33485 oboInOwl:hasExactSynonym "chalcogen oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcogen oxoanions" ; oboInOwl:id "CHEBI:33485" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chalcogen oxoanion" ; rdfs:subClassOf obo:CHEBI_35406 . obo:CHEBI_33497 obo:IAO_0000115 "A molecular entity containing one or more atoms of a transition element." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "transition element molecular entities", "transition metal molecular entity" ; oboInOwl:id "CHEBI:33497" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "transition element molecular entity" ; rdfs:subClassOf obo:CHEBI_23367, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_27081 ] . obo:CHEBI_33504 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkali metal cations" ; oboInOwl:id "CHEBI:33504" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkali metal cation" ; rdfs:subClassOf obo:CHEBI_25213 . obo:CHEBI_33513 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkaline earth cations", "alkaline earth metal cation", "alkaline-earth metal cations" ; oboInOwl:id "CHEBI:33513" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkaline earth cation" ; rdfs:subClassOf obo:CHEBI_25213, obo:CHEBI_33299 . obo:CHEBI_33521 obo:IAO_0000115 "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." ; oboInOwl:hasAlternativeId "CHEBI:25217", "CHEBI:6788" ; oboInOwl:hasDbXref "KEGG:C00050", "PMID:21784043", "Wikipedia:Metal" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "elemental metal", "elemental metals", "metal element", "metal elements", "metals" ; oboInOwl:id "CHEBI:33521" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "metal atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_33535 oboInOwl:hasExactSynonym "sulfur hydride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydrides of sulfur", "sulfur hydrides", "sulphur hydrides" ; oboInOwl:id "CHEBI:33535" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur hydride" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_36902 . obo:CHEBI_33543 obo:IAO_0000115 "The sulfur oxoanion formed by deprotonation of sulfonic acid." ; chebi:charge "-1" ; chebi:formula "HO3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)/p-1" ; chebi:inchikey "BDHFUVZGWQCTTF-UHFFFAOYSA-M" ; chebi:mass "81.07214" ; chebi:monoisotopicmass "80.96519" ; chebi:smiles "[H]S([O-])(=O)=O" ; oboInOwl:hasDbXref "Gmelin:971569" ; oboInOwl:hasExactSynonym "hydridotrioxidosulfate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SHO3(-)", "[SHO3](-)", "sulfonates" ; oboInOwl:id "CHEBI:33543" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfonate" ; rdfs:subClassOf obo:CHEBI_33482, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29214 ] . obo:CHEBI_33551 obo:IAO_0000115 "An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon." ; chebi:charge "0" ; chebi:formula "HO3SR" ; chebi:mass "81.07100" ; chebi:monoisotopicmass "80.96464" ; chebi:smiles "OS([*])(=O)=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organosulfonic acids", "sulfonic acids" ; oboInOwl:id "CHEBI:33551" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organosulfonic acid" ; rdfs:subClassOf obo:CHEBI_33261, obo:CHEBI_33552, obo:CHEBI_64709, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29922 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33249 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33554 ] . obo:CHEBI_33552 oboInOwl:hasExactSynonym "sulfonic acid derivative" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "derivatives of sulfonic acid", "sulfonic acid derivatives" ; oboInOwl:id "CHEBI:33552" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfonic acid derivative" ; rdfs:subClassOf obo:CHEBI_33424, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_29214 ] . obo:CHEBI_33554 obo:IAO_0000115 "An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid." ; chebi:charge "-1" ; chebi:formula "O3SR" ; chebi:mass "80.064" ; chebi:monoisotopicmass "79.95681" ; chebi:smiles "*S([O-])(=O)=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organosulfonate", "organosulfonate oxoanions", "organosulfonates" ; oboInOwl:id "CHEBI:33554" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organosulfonate oxoanion" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33543 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33551 ] . obo:CHEBI_33558 obo:IAO_0000115 "An amino-acid anion obtained by deprotonation of any alpha-amino acid." ; oboInOwl:hasExactSynonym "alpha-amino-acid anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-amino acid anions", "alpha-amino-acid anions" ; oboInOwl:id "CHEBI:33558" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-amino-acid anion" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33704 ] . obo:CHEBI_33559 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "s-block element", "s-block elements" ; oboInOwl:id "CHEBI:33559" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "s-block element atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_33560 obo:IAO_0000115 "Any main group element atom belonging to the p-block of the periodic table." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "p-block element", "p-block elements" ; oboInOwl:id "CHEBI:33560" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "p-block element atom" ; rdfs:subClassOf obo:CHEBI_33318 . obo:CHEBI_33561 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "d-block element", "d-block elements" ; oboInOwl:id "CHEBI:33561" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "d-block element atom" ; rdfs:subClassOf obo:CHEBI_27081 . obo:CHEBI_33566 obo:IAO_0000115 "Any compound containing an o-diphenol component." ; chebi:charge "0" ; chebi:formula "C6H2O2R4" ; chebi:mass "106.079" ; chebi:monoisotopicmass "106.00548" ; chebi:smiles "OC1=C(O)C(*)=C(*)C(*)=C1*" ; oboInOwl:hasAlternativeId "CHEBI:134187", "CHEBI:13628", "CHEBI:18862" ; oboInOwl:hasDbXref "KEGG:C15571" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2-benzenediols", "a catechol", "benzene-1,2-diols" ; oboInOwl:id "CHEBI:33566" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "catechols" ; rdfs:subClassOf obo:CHEBI_33570 . obo:CHEBI_33567 obo:IAO_0000115 "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." ; chebi:charge "0" ; chebi:formula "C8H9NO2R2" ; chebi:mass "151.163" ; chebi:monoisotopicmass "151.06333" ; oboInOwl:hasAlternativeId "CHEBI:23056", "CHEBI:3468" ; oboInOwl:hasDbXref "KEGG:C02012" ; oboInOwl:hasExactSynonym "Catecholamine", "catecholamines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C8H9NO2R2", "catecholamines" ; oboInOwl:id "CHEBI:33567" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "catecholamine" ; rdfs:subClassOf obo:CHEBI_25375, obo:CHEBI_33566 . obo:CHEBI_33569 obo:IAO_0000115 "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted." ; chebi:charge "0" ; chebi:formula "C8H11NO3" ; chebi:inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2" ; chebi:inchikey "SFLSHLFXELFNJZ-UHFFFAOYSA-N" ; chebi:mass "169.17788" ; chebi:monoisotopicmass "169.07389" ; chebi:smiles "NCC(O)c1ccc(O)c(O)c1" ; oboInOwl:hasDbXref "Beilstein:2210994", "CAS:138-65-8", "Gmelin:863925", "LINCS:LSM-5181" ; oboInOwl:hasExactSynonym "4-(2-amino-1-hydroxyethyl)benzene-1,2-diol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "noradrenalina", "norepinephrine" ; oboInOwl:id "CHEBI:33569" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "noradrenaline" ; rdfs:subClassOf obo:CHEBI_33567, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76967 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_166902 ] . obo:CHEBI_33570 oboInOwl:hasAlternativeId "CHEBI:22705", "CHEBI:22711" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33570" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "benzenediols" ; rdfs:subClassOf obo:CHEBI_33853 . obo:CHEBI_33571 obo:IAO_0000115 "The S-enantiomer of noradrenaline." ; chebi:charge "0" ; chebi:formula "C8H11NO3" ; chebi:inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1" ; chebi:inchikey "SFLSHLFXELFNJZ-MRVPVSSYSA-N" ; chebi:mass "169.17788" ; chebi:monoisotopicmass "169.07389" ; chebi:smiles "NC[C@@H](O)c1ccc(O)c(O)c1" ; oboInOwl:hasDbXref "Beilstein:2937999", "LINCS:LSM-37072", "Reaxys:2937999" ; oboInOwl:hasExactSynonym "4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33571" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(S)-noradrenaline" ; rdfs:subClassOf obo:CHEBI_33569, [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_18357 ] . obo:CHEBI_33575 obo:IAO_0000115 "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." ; chebi:charge "0" ; chebi:formula "CHO2R" ; chebi:mass "45.01740" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "OC([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13428", "CHEBI:13627", "CHEBI:23027" ; oboInOwl:hasDbXref "PMID:17147560", "PMID:18433345", "Wikipedia:Carboxylic_acid" ; oboInOwl:hasExactSynonym "carboxylic acid", "carboxylic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Carbonsaeure", "Carbonsaeuren", "Karbonsaeure", "RC(=O)OH", "acide carboxylique", "acides carboxyliques", "acido carboxilico", "acidos carboxilicos" ; oboInOwl:id "CHEBI:33575" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carboxylic acid" ; rdfs:subClassOf obo:CHEBI_35605, obo:CHEBI_36586, obo:CHEBI_64709, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_46883 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29067 ] . obo:CHEBI_33576 obo:IAO_0000115 "Any carboxylic acid having a sulfur substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "S-containing carboxylic acid", "S-containing carboxylic acids", "sulfur-containing carboxylic acids" ; oboInOwl:id "CHEBI:33576" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur-containing carboxylic acid" ; rdfs:subClassOf obo:CHEBI_33261, obo:CHEBI_33575 . obo:CHEBI_33579 obo:IAO_0000115 "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "main group compounds", "main group molecular entities" ; oboInOwl:id "CHEBI:33579" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "main group molecular entity" ; rdfs:subClassOf obo:CHEBI_23367, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33318 ] . obo:CHEBI_33582 oboInOwl:hasExactSynonym "carbon group molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon group molecular entities" ; oboInOwl:id "CHEBI:33582" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbon group molecular entity" ; rdfs:subClassOf obo:CHEBI_33675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33306 ] . obo:CHEBI_33595 obo:IAO_0000115 "Any molecule that consists of a series of atoms joined together to form a ring." ; oboInOwl:hasDbXref "Wikipedia:Cyclic_compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic compounds" ; oboInOwl:id "CHEBI:33595" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic compound" ; rdfs:subClassOf obo:CHEBI_25367 . obo:CHEBI_33597 obo:IAO_0000115 "A cyclic compound having as ring members atoms of the same element only." ; oboInOwl:hasExactSynonym "homocyclic compound", "homocyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isocyclic compounds" ; oboInOwl:id "CHEBI:33597" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "homocyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33598 obo:IAO_0000115 "A homocyclic compound in which all of the ring members are carbon atoms." ; oboInOwl:hasExactSynonym "carbocyclic compound", "carbocyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbocycle" ; oboInOwl:id "CHEBI:33598" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbocyclic compound" ; rdfs:subClassOf obo:CHEBI_33597, obo:CHEBI_33832 . obo:CHEBI_33599 obo:IAO_0000115 "A compound having one atom as the only common member of two rings." ; oboInOwl:hasExactSynonym "spiro compound", "spiro compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "spiro-fused compounds", "spirocycle", "spirocycles", "spirocyclic compound", "spirocyclic compounds", "spirofused compounds" ; oboInOwl:id "CHEBI:33599" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "spiro compound" ; rdfs:subClassOf obo:CHEBI_33635 . obo:CHEBI_33608 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydrogen compounds", "hydrogen molecular entities" ; oboInOwl:id "CHEBI:33608" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_49637 ] . obo:CHEBI_33635 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polycyclic compounds" ; oboInOwl:id "CHEBI:33635" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polycyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33636 obo:IAO_0000115 "A molecule that features two fused rings." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bicyclic compounds" ; oboInOwl:id "CHEBI:33636" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bicyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33639 obo:IAO_0000115 "A polycyclic compound in which one ring contains two, and only two, atoms in common with each of two or more rings of a contiguous series of rings. Such compounds have n common faces and less than 2n common atoms." ; oboInOwl:hasExactSynonym "ortho- and peri-fused polycyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ortho- and peri-fused compounds" ; oboInOwl:id "CHEBI:33639" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ortho- and peri-fused compound" ; rdfs:subClassOf obo:CHEBI_35293 . obo:CHEBI_33653 obo:IAO_0000115 "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds." ; oboInOwl:hasExactSynonym "aliphatic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33653" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aliphatic compound" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_33655 obo:IAO_0000115 "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." ; oboInOwl:hasExactSynonym "aromatic compounds", "aromatic molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aromatics", "aromatische Verbindungen" ; oboInOwl:id "CHEBI:33655" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aromatic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33658 obo:IAO_0000115 "Any monocyclic or polycyclic aromatic hydrocarbon." ; oboInOwl:hasExactSynonym "arene", "arenes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aromatic hydrocarbons" ; oboInOwl:id "CHEBI:33658" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "arene" ; rdfs:subClassOf obo:CHEBI_33659, obo:CHEBI_33663 . obo:CHEBI_33659 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic aromatic compounds" ; oboInOwl:id "CHEBI:33659" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic aromatic compound" ; rdfs:subClassOf obo:CHEBI_33655, obo:CHEBI_33832 . obo:CHEBI_33661 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monocyclic compounds" ; oboInOwl:id "CHEBI:33661" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monocyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33663 oboInOwl:hasExactSynonym "cyclic hydrocarbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic hydrocarbons" ; oboInOwl:id "CHEBI:33663" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic hydrocarbon" ; rdfs:subClassOf obo:CHEBI_24632, obo:CHEBI_33598 . obo:CHEBI_33666 oboInOwl:hasExactSynonym "polycyclic hydrocarbon", "polycyclic hydrocarbons" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33666" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polycyclic hydrocarbon" ; rdfs:subClassOf obo:CHEBI_33663, obo:CHEBI_35294 . obo:CHEBI_33670 oboInOwl:hasExactSynonym "heteromonocyclic compound", "heteromonocyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33670" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heteromonocyclic compound" ; rdfs:subClassOf obo:CHEBI_33661, obo:CHEBI_5686 . obo:CHEBI_33671 obo:IAO_0000115 "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." ; oboInOwl:hasExactSynonym "heteropolycyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyheterocyclic compounds" ; oboInOwl:id "CHEBI:33671" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heteropolycyclic compound" ; rdfs:subClassOf obo:CHEBI_33635, obo:CHEBI_5686 . obo:CHEBI_33672 obo:IAO_0000115 "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." ; oboInOwl:hasExactSynonym "heterobicyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33672" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heterobicyclic compound" ; rdfs:subClassOf obo:CHEBI_33636, obo:CHEBI_5686 . obo:CHEBI_33673 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "zinc group molecular entities" ; oboInOwl:id "CHEBI:33673" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "zinc group molecular entity" ; rdfs:subClassOf obo:CHEBI_33676, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33340 ] . obo:CHEBI_33674 obo:IAO_0000115 "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." ; oboInOwl:hasExactSynonym "s-block molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "s-block compounds", "s-block molecular entities" ; oboInOwl:id "CHEBI:33674" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "s-block molecular entity" ; rdfs:subClassOf obo:CHEBI_33579, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33559 ] . obo:CHEBI_33675 obo:IAO_0000115 "A main group molecular entity that contains one or more atoms of a p-block element." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "p-block compounds", "p-block molecular entities", "p-block molecular entitiy" ; oboInOwl:id "CHEBI:33675" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "p-block molecular entity" ; rdfs:subClassOf obo:CHEBI_33579, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33560 ] . obo:CHEBI_33676 obo:IAO_0000115 "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element." ; oboInOwl:hasExactSynonym "d-block molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "d-block compounds", "d-block molecular entities" ; oboInOwl:id "CHEBI:33676" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "d-block molecular entity" ; rdfs:subClassOf obo:CHEBI_33497, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33561 ] . obo:CHEBI_33692 obo:IAO_0000115 "Hydrides are chemical compounds of hydrogen with other chemical elements." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33692" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrides" ; rdfs:subClassOf obo:CHEBI_33608, obo:CHEBI_37577 . obo:CHEBI_33693 oboInOwl:hasExactSynonym "oxygen hydride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydrides of oxygen", "oxygen hydrides" ; oboInOwl:id "CHEBI:33693" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxygen hydride" ; rdfs:subClassOf obo:CHEBI_36902 . obo:CHEBI_33694 obo:IAO_0000115 "A macromolecule formed by a living organism." ; oboInOwl:hasExactSynonym "biopolymer" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Biopolymere", "biomacromolecules", "biopolymers" ; oboInOwl:id "CHEBI:33694" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "biomacromolecule" ; rdfs:subClassOf obo:CHEBI_33839, obo:CHEBI_50860 . obo:CHEBI_33695 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "genetically encoded biomacromolecules", "genetically encoded biopolymers", "information biomacromolecules", "information biopolymers", "information macromolecule", "information macromolecules" ; oboInOwl:id "CHEBI:33695" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "information biomacromolecule" ; rdfs:subClassOf obo:CHEBI_33694 . obo:CHEBI_33696 obo:IAO_0000115 "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ; oboInOwl:hasExactSynonym "nucleic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NA", "Nukleinsaeure", "Nukleinsaeuren", "acide nucleique", "acides nucleiques", "acido nucleico", "acidos nucleicos" ; oboInOwl:id "CHEBI:33696" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleic acid" ; rdfs:subClassOf obo:CHEBI_15986, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33791 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50297 ] . obo:CHEBI_33697 obo:IAO_0000115 "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." ; oboInOwl:hasDbXref "CAS:63231-63-0" ; oboInOwl:hasExactSynonym "ribonucleic acid", "ribonucleic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RNA", "RNS", "Ribonukleinsaeure", "pentosenucleic acids", "ribonucleic acids", "ribose nucleic acid", "yeast nucleic acid" ; oboInOwl:id "CHEBI:33697" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribonucleic acid" ; rdfs:subClassOf obo:CHEBI_33696, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33792 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50299 ] . obo:CHEBI_33699 obo:IAO_0000115 "An RNA molecule that transfers the coding information for protein synthesis from the chromosomes to the ribosomes mRNA is formed from a DNA template by transcription. It may be a copy of a single gene or of several adjacent genes (polycistronic mRNA). On the ribosome, the sequence is converted into the programmed amino acid sequence through translation." ; oboInOwl:hasExactSynonym "messenger RNA" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mRNA", "template RNA" ; oboInOwl:id "CHEBI:33699" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "messenger RNA" ; rdfs:subClassOf obo:CHEBI_33697 . obo:CHEBI_33700 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical amino-acid residue", "canonical amino-acid residues", "common amino acid residues", "proteinogenic amino-acid residues", "standard amino acid residues", "standard amino-acid residues" ; oboInOwl:id "CHEBI:33700" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "proteinogenic amino-acid residue" ; rdfs:subClassOf obo:CHEBI_33710 . obo:CHEBI_33702 obo:IAO_0000115 "A cation consisting of more than one atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic cations" ; oboInOwl:id "CHEBI:33702" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polyatomic cation" ; rdfs:subClassOf obo:CHEBI_36358, obo:CHEBI_36916 . obo:CHEBI_33703 oboInOwl:hasExactSynonym "amino-acid cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino acid cation", "amino-acid cations" ; oboInOwl:id "CHEBI:33703" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amino-acid cation" ; rdfs:subClassOf obo:CHEBI_33702 . obo:CHEBI_33704 obo:IAO_0000115 "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.05870" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "NC([*])C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:10208", "CHEBI:13779", "CHEBI:22442", "CHEBI:2642" ; oboInOwl:hasDbXref "KEGG:C00045", "KEGG:C05167" ; oboInOwl:hasExactSynonym "alpha-amino acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Amino acid", "Amino acids", "alpha-amino acids", "alpha-amino carboxylic acids" ; oboInOwl:id "CHEBI:33704" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-amino acid" ; rdfs:subClassOf obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33558 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_78608 ] . obo:CHEBI_33707 obo:IAO_0000115 "A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position gamma to the carboxy group." ; oboInOwl:hasExactSynonym "gamma-amino acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gamma-amino acids" ; oboInOwl:id "CHEBI:33707" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "gamma-amino acid" ; rdfs:subClassOf obo:CHEBI_83820, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_71666 ] . obo:CHEBI_33708 obo:IAO_0000115 "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." ; oboInOwl:hasExactSynonym "amino-acid residue" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino acid residue", "amino-acid residues" ; oboInOwl:id "CHEBI:33708" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amino-acid residue" ; rdfs:subClassOf obo:CHEBI_33247, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_33709 ] . obo:CHEBI_33709 obo:IAO_0000115 "A carboxylic acid containing one or more amino groups." ; oboInOwl:hasAlternativeId "CHEBI:13815", "CHEBI:22477" ; oboInOwl:hasDbXref "Wikipedia:Amino_acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aminocarbonsaeure", "Aminokarbonsaeure", "Aminosaeure", "amino acids" ; oboInOwl:id "CHEBI:33709" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amino acid" ; rdfs:subClassOf obo:CHEBI_33575, obo:CHEBI_50047, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_37022 ] . obo:CHEBI_33710 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-amino-acid residues" ; oboInOwl:id "CHEBI:33710" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-amino-acid residue" ; rdfs:subClassOf obo:CHEBI_33708, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_33704 ] . obo:CHEBI_33719 oboInOwl:hasExactSynonym "alpha-amino-acid cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-amino acid cations", "alpha-amino-acid cations" ; oboInOwl:id "CHEBI:33719" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-amino-acid cation" ; rdfs:subClassOf obo:CHEBI_33703 . obo:CHEBI_33720 oboInOwl:hasExactSynonym "carbohydrate acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrate acids" ; oboInOwl:id "CHEBI:33720" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbohydrate acid" ; rdfs:subClassOf obo:CHEBI_16646, obo:CHEBI_33575, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33721 ] . obo:CHEBI_33721 oboInOwl:hasExactSynonym "carbohydrate acid anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrate acid anions" ; oboInOwl:id "CHEBI:33721" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbohydrate acid anion" ; rdfs:subClassOf obo:CHEBI_29067, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33720 ] . obo:CHEBI_33744 oboInOwl:hasExactSynonym "iron group molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iron group molecular entities" ; oboInOwl:id "CHEBI:33744" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iron group molecular entity" ; rdfs:subClassOf obo:CHEBI_33676, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33356 ] . obo:CHEBI_33745 oboInOwl:hasExactSynonym "copper group molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "copper group molecular entities" ; oboInOwl:id "CHEBI:33745" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "copper group molecular entity" ; rdfs:subClassOf obo:CHEBI_33676, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33366 ] . obo:CHEBI_33791 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical nucleoside residues", "common nucleoside residues", "nucleoside residue", "standard nucleoside residues" ; oboInOwl:id "CHEBI:33791" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "canonical nucleoside residue" ; rdfs:subClassOf obo:CHEBI_50320 . obo:CHEBI_33792 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N", "Nuc", "canonical ribonucleoside residues", "common ribonucleoside residue", "common ribonucleoside residues", "standard ribonucleoside residues" ; oboInOwl:id "CHEBI:33792" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "canonical ribonucleoside residue" ; rdfs:subClassOf obo:CHEBI_33791 . obo:CHEBI_33793 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical deoxyribonucleoside residues", "common 2'-deoxyribonucleoside residue", "common 2'-deoxyribonucleoside residues", "dN", "dNuc", "standard deoxyribonucleoside residues" ; oboInOwl:id "CHEBI:33793" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "canonical deoxyribonucleoside residue" ; rdfs:subClassOf obo:CHEBI_33791 . obo:CHEBI_33822 obo:IAO_0000115 "An organic compound having at least one hydroxy group attached to a carbon atom." ; oboInOwl:hasAlternativeId "CHEBI:64710" ; oboInOwl:hasExactSynonym "hydroxy compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic alcohol", "organic hydroxy compounds" ; oboInOwl:id "CHEBI:33822" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic hydroxy compound" ; rdfs:subClassOf obo:CHEBI_24651, obo:CHEBI_50860 . obo:CHEBI_33832 obo:IAO_0000115 "Any organic molecule that consists of atoms connected in the form of a ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic cyclic compounds" ; oboInOwl:id "CHEBI:33832" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic cyclic compound" ; rdfs:subClassOf obo:CHEBI_33595, obo:CHEBI_72695 . obo:CHEBI_33833 obo:IAO_0000115 "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." ; oboInOwl:hasExactSynonym "heteroarenes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hetarenes" ; oboInOwl:id "CHEBI:33833" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heteroarene" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_33659 . obo:CHEBI_33836 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "benzenoid aromatic compounds", "benzenoid compound" ; oboInOwl:id "CHEBI:33836" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "benzenoid aromatic compound" ; rdfs:subClassOf obo:CHEBI_33598, obo:CHEBI_33659 . obo:CHEBI_33837 obo:IAO_0000115 "Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion." ; oboInOwl:hasDbXref "COMe:PRX000001" ; oboInOwl:hasExactSynonym "conjugated proteins" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "complex protein" ; oboInOwl:id "CHEBI:33837" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "conjugated protein" ; rdfs:subClassOf obo:CHEBI_36080, obo:PR_000000001 . obo:CHEBI_33838 obo:IAO_0000115 "An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents." ; chebi:charge "0" ; chebi:formula "C5H8O3R2" ; chebi:mass "116.115" ; chebi:monoisotopicmass "116.04734" ; chebi:smiles "[C@H]1([C@H]([C@@H](*)[C@@H](O1)*)O)CO" ; oboInOwl:hasAlternativeId "CHEBI:13661", "CHEBI:25611", "CHEBI:7647" ; oboInOwl:hasDbXref "KEGG:C00801", "Wikipedia:Nucleoside" ; oboInOwl:hasExactSynonym "Nucleoside", "nucleosides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a nucleoside", "nucleosides" ; oboInOwl:id "CHEBI:33838" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside" ; rdfs:subClassOf obo:CHEBI_21731, obo:CHEBI_26912, obo:CHEBI_61120 . obo:CHEBI_33839 obo:IAO_0000115 "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasDbXref "Wikipedia:Macromolecule" ; oboInOwl:hasExactSynonym "macromolecule" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "macromolecules", "polymer", "polymer molecule", "polymers" ; oboInOwl:id "CHEBI:33839" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "macromolecule" ; rdfs:subClassOf obo:CHEBI_36357 . obo:CHEBI_33848 obo:IAO_0000115 "A polycyclic aromatic hydrocarbon." ; oboInOwl:hasDbXref "PMID:15198916", "PMID:25679824", "Wikipedia:Polycyclic_aromatic_hydrocarbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "PAH", "PAHs", "polycyclic arenes", "polycyclic aromatic hydrocarbons" ; oboInOwl:id "CHEBI:33848" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polycyclic arene" ; rdfs:subClassOf obo:CHEBI_33658, obo:CHEBI_33666, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50903 ] . obo:CHEBI_33853 obo:IAO_0000115 "Compounds having one or more hydroxy groups attached to a benzene or other arene ring.", "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." ; chebi:charge "0" ; chebi:formula "C6HOR5" ; chebi:mass "89.072" ; chebi:monoisotopicmass "89.00274" ; chebi:smiles "C1(=C(C(=C(C(=C1*)*)*)*)*)O" ; oboInOwl:hasAlternativeId "CHEBI:13664", "CHEBI:13825", "CHEBI:25969", "CHEBI:2857" ; oboInOwl:hasDbXref "KEGG:C15584", "MetaCyc:Phenols", "Wikipedia:Phenols" ; oboInOwl:hasExactSynonym "phenols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aryl alcohol", "a phenol", "arenols", "aryl alcohol" ; oboInOwl:id "CHEBI:33853" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phenols" ; rdfs:subClassOf obo:CHEBI_33659, obo:CHEBI_33822 . obo:CHEBI_33855 obo:IAO_0000115 "Any aldehyde in which the carbonyl group is attached to an aromatic moiety." ; chebi:charge "0" ; chebi:formula "CHOR" ; chebi:mass "29.018" ; chebi:monoisotopicmass "29.00274" ; chebi:smiles "*C(=O)[H]" ; oboInOwl:hasAlternativeId "CHEBI:13819", "CHEBI:22621", "CHEBI:2832", "CHEBI:87908" ; oboInOwl:hasDbXref "KEGG:C00193", "MetaCyc:Aryl-Aldehyde" ; oboInOwl:hasExactSynonym "arenecarbaldehyde" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aromatic aldehyde", "an aromatic aldehyde", "arenecarbaldehydes", "aryl aldehyde", "aryl aldehydes" ; oboInOwl:id "CHEBI:33855" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "arenecarbaldehyde" ; rdfs:subClassOf obo:CHEBI_17478, obo:CHEBI_33659 . obo:CHEBI_33860 obo:IAO_0000115 "An amino compound in which the amino group is linked directly to an aromatic system." ; oboInOwl:hasAlternativeId "CHEBI:13827", "CHEBI:22622", "CHEBI:22646", "CHEBI:2834", "CHEBI:2863" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aromatic amines", "aryl amine", "aryl amines", "arylamine", "arylamines" ; oboInOwl:id "CHEBI:33860" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aromatic amine" ; rdfs:subClassOf obo:CHEBI_33659, obo:CHEBI_50047 . obo:CHEBI_33861 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "transition element coordination entities", "transition metal coordination compounds", "transition metal coordination entities" ; oboInOwl:id "CHEBI:33861" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "transition element coordination entity" ; rdfs:subClassOf obo:CHEBI_33240, obo:CHEBI_33497 . obo:CHEBI_33892 oboInOwl:hasExactSynonym "iron coordination entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iron coordination compounds", "iron coordination entities" ; oboInOwl:id "CHEBI:33892" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iron coordination entity" ; rdfs:subClassOf obo:CHEBI_24873, obo:CHEBI_33861 . obo:CHEBI_33893 obo:IAO_0000115 "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." ; oboInOwl:hasExactSynonym "reagent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "reactif", "reactivo", "reagents" ; oboInOwl:id "CHEBI:33893" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "reagent" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_33909 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metal-tetrapyrrole", "metal-tetrapyrrole complex", "metallotetrapyrroles" ; oboInOwl:id "CHEBI:33909" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "metallotetrapyrrole" ; rdfs:subClassOf obo:CHEBI_36309 . obo:CHEBI_33916 obo:IAO_0000115 "A pentose with a (potential) aldehyde group at one end." ; oboInOwl:hasDbXref "PMID:10723607" ; oboInOwl:hasExactSynonym "aldopentose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldopentoses" ; oboInOwl:id "CHEBI:33916" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aldopentose" ; rdfs:subClassOf obo:CHEBI_15693, obo:CHEBI_25901 . obo:CHEBI_33917 obo:IAO_0000115 "A hexose with a (potential) aldehyde group at one end." ; oboInOwl:hasAlternativeId "CHEBI:2558" ; oboInOwl:hasExactSynonym "aldohexose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldohexoses" ; oboInOwl:id "CHEBI:33917" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aldohexose" ; rdfs:subClassOf obo:CHEBI_15693, obo:CHEBI_18133 . obo:CHEBI_33937 obo:IAO_0000115 "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "macronutrients" ; oboInOwl:id "CHEBI:33937" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "macronutrient" ; rdfs:subClassOf obo:CHEBI_33284 . obo:CHEBI_33942 obo:IAO_0000115 "Any aldopentose where the open-chain form has all the hydroxy groups on the same side in the Fischer projection. Occurrs in two enantiomeric forms, D- and L-ribose, of which only the former is found in nature." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:mass "150.130" ; chebi:monoisotopicmass "150.05282" ; oboInOwl:hasAlternativeId "CHEBI:26564" ; oboInOwl:hasExactSynonym "ribo-pentose", "ribose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Rib" ; oboInOwl:id "CHEBI:33942" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribose" ; rdfs:subClassOf obo:CHEBI_33916 . obo:CHEBI_33958 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halide salts", "halides" ; oboInOwl:id "CHEBI:33958" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halide salt" ; rdfs:subClassOf obo:CHEBI_24866, obo:CHEBI_37578, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16042 ] . obo:CHEBI_33964 oboInOwl:hasExactSynonym "silver molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "silver compounds", "silver molecular entities" ; oboInOwl:id "CHEBI:33964" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "silver molecular entity" ; rdfs:subClassOf obo:CHEBI_33745, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_30512 ] . obo:CHEBI_33966 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33966" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental silver" ; rdfs:subClassOf obo:CHEBI_33964 . obo:CHEBI_34905 obo:IAO_0000115 "An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions." ; chebi:charge "+2" ; chebi:formula "C12H14N2" ; chebi:inchi "InChI=1S/C12H14N2/c1-13-7-3-11(4-8-13)12-5-9-14(2)10-6-12/h3-10H,1-2H3/q+2" ; chebi:inchikey "INFDPOAKFNIJBF-UHFFFAOYSA-N" ; chebi:mass "186.25304" ; chebi:monoisotopicmass "186.11460" ; chebi:smiles "C[n+]1ccc(cc1)-c1cc[n+](C)cc1" ; oboInOwl:hasDbXref "Beilstein:3590305", "CAS:4685-14-7", "Chemspider:15147", "FooDB:FDB011120", "Gmelin:51125", "KEGG:C14701", "PMID:11349957", "PMID:18620719", "PMID:20377249", "PMID:20582739", "PMID:21151885", "PMID:21236547", "PMID:21300143", "PMID:21318114", "PMID:21429624", "PMID:21493003", "PMID:21598522", "PMID:21616728", "PMID:21619794", "PMID:21619822", "PMID:21750730", "PMID:21777615", "PMID:21787677", "PMID:21802509", "PPDB:505", "Pesticides:paraquat", "Reaxys:3590305" ; oboInOwl:hasExactSynonym "1,1'-dimethyl-[4,4'-bipyridin]-1,1'-diium", "Paraquat" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1'-Dimethyl-4,4'-bipyridinium", "1,1'-dimethyl-4,4'-bipyridyldiylium", "N,N'-dimethyl-4,4'-bipyridinium", "N,N'-dimethyl-4,4'-bipyridinium dication", "dimethyl viologen", "methyl viologen ion(2+)", "paraquat dication", "paraquat ion" ; oboInOwl:id "CHEBI:34905" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "paraquat" ; rdfs:subClassOf obo:CHEBI_25697, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24527 ], [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_30985 ] . obo:CHEBI_350546 obo:IAO_0000115 "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C10H13N2O" ; chebi:inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1" ; chebi:inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-O" ; chebi:mass "177.22250" ; chebi:monoisotopicmass "177.10224" ; chebi:smiles "[NH3+]CCc1c[nH]c2ccc(O)cc12" ; oboInOwl:hasExactSynonym "2-(5-hydroxy-1H-indol-3-yl)ethanaminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "serotonin", "serotonin cation" ; oboInOwl:id "CHEBI:350546" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "serotonin(1+)" ; rdfs:subClassOf obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_28790 ] . obo:CHEBI_35106 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nitrogen hydrides" ; oboInOwl:id "CHEBI:35106" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nitrogen hydride" ; rdfs:subClassOf obo:CHEBI_35881, obo:CHEBI_51143 . obo:CHEBI_35107 obo:IAO_0000115 "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "azanes" ; oboInOwl:id "CHEBI:35107" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "azane" ; rdfs:subClassOf obo:CHEBI_35106 . obo:CHEBI_35131 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldose phosphates" ; oboInOwl:id "CHEBI:35131" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aldose phosphate" ; rdfs:subClassOf obo:CHEBI_33447 . obo:CHEBI_35155 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35155" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental calcium" ; rdfs:subClassOf obo:CHEBI_22985 . obo:CHEBI_35186 obo:IAO_0000115 "A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]." ; oboInOwl:hasExactSynonym "terpene", "terpenes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Terpen", "terpenes", "terpeno", "terpenos" ; oboInOwl:id "CHEBI:35186" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "terpene" ; rdfs:subClassOf obo:CHEBI_24632, obo:CHEBI_24913 . obo:CHEBI_35190 obo:IAO_0000115 "A C20 terpene." ; oboInOwl:hasExactSynonym "diterpenes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Diterpen", "diterpenes", "diterpeno", "diterpenos" ; oboInOwl:id "CHEBI:35190" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diterpene" ; rdfs:subClassOf obo:CHEBI_35186 . obo:CHEBI_35195 obo:IAO_0000115 "A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces." ; oboInOwl:hasExactSynonym "surfactant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "surface active agent", "surfactants" ; oboInOwl:id "CHEBI:35195" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "surfactant" ; rdfs:subClassOf obo:CHEBI_63046 . obo:CHEBI_35221 obo:IAO_0000115 "A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization." ; oboInOwl:hasDbXref "Wikipedia:Antimetabolite" ; oboInOwl:hasExactSynonym "antimetabolite" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimetabolites" ; oboInOwl:id "CHEBI:35221" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimetabolite" ; rdfs:subClassOf obo:CHEBI_52206 . obo:CHEBI_35222 obo:IAO_0000115 "A substance that diminishes the rate of a chemical reaction." ; oboInOwl:hasExactSynonym "inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inhibidor", "inhibiteur", "inhibitors" ; oboInOwl:id "CHEBI:35222" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inhibitor" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_35223 obo:IAO_0000115 "A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction." ; oboInOwl:hasExactSynonym "catalyst" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Katalysator", "catalizador", "catalyseur" ; oboInOwl:id "CHEBI:35223" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "catalyst" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_35230 obo:IAO_0000115 "A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth." ; oboInOwl:hasExactSynonym "fossil fuel" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35230" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fossil fuel" ; rdfs:subClassOf obo:CHEBI_33292 . obo:CHEBI_35235 chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "[NH3+][C@@H](CS)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:49993" ; oboInOwl:hasExactSynonym "(2R)-2-ammonio-3-sulfanylpropanoate", "L-cysteine zwitterion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R)-2-ammonio-3-mercaptopropanoate", "L-cysteine" ; oboInOwl:id "CHEBI:35235" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-cysteine zwitterion" ; rdfs:subClassOf obo:CHEBI_35237, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32442 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32445 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_35236 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17561 ] . obo:CHEBI_35236 chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "[NH3+][C@H](CS)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:2352354" ; oboInOwl:hasExactSynonym "(2S)-2-ammonio-3-sulfanylpropanoate", "D-cysteine zwitterion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2S)-2-ammonio-3-mercaptopropanoate", "D-cysteine" ; oboInOwl:id "CHEBI:35236" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-cysteine zwitterion" ; rdfs:subClassOf obo:CHEBI_35237, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32449 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32451 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_35235 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16375 ] . obo:CHEBI_35237 chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "[NH3+]C(CS)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:49992" ; oboInOwl:hasExactSynonym "2-ammonio-3-sulfanylpropanoate", "cysteine zwitterion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)H3N-CH(CH2SH)-COO(-)", "2-ammonio-3-mercaptopropanoate" ; oboInOwl:id "CHEBI:35237" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cysteine zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32456 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32458 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_15356 ] . obo:CHEBI_35238 obo:IAO_0000115 "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." ; oboInOwl:hasExactSynonym "amino acid zwitterion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35238" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_27369 . obo:CHEBI_35267 obo:IAO_0000115 "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." ; chebi:charge "+1" ; chebi:formula "NR4" ; chebi:mass "14.00670" ; chebi:monoisotopicmass "14.00307" ; chebi:smiles "[*][N+]([*])([*])[*]" ; oboInOwl:hasAlternativeId "CHEBI:26470", "CHEBI:8693" ; oboInOwl:hasDbXref "KEGG:C06703" ; oboInOwl:hasExactSynonym "quaternary ammonium ion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Quaternary amine", "a quaternary ammonium", "quaternary ammonium ions" ; oboInOwl:id "CHEBI:35267" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "quaternary ammonium ion" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274 . obo:CHEBI_35273 obo:IAO_0000115 "Derivatives of ammonium compounds, (NH4(+))Y(-), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." ; oboInOwl:hasAlternativeId "CHEBI:26468", "CHEBI:35268" ; oboInOwl:hasExactSynonym "quaternary ammonium compounds", "quaternary ammonium salt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "quaternary ammonium compound", "quaternary ammonium salts" ; oboInOwl:id "CHEBI:35273" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "quaternary ammonium salt" ; rdfs:subClassOf obo:CHEBI_26469, obo:CHEBI_46850 . obo:CHEBI_35274 obo:IAO_0000115 "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ammonium ion derivatives", "azanium ion derivative", "azanium ion derivatives" ; oboInOwl:id "CHEBI:35274" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ammonium ion derivative" ; rdfs:subClassOf obo:CHEBI_33702, obo:CHEBI_51143, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_28938 ] . obo:CHEBI_35276 obo:IAO_0000115 "Compounds (NH4(+))Y(-) and derivatives, in which one or more of the hydrogens bonded to nitrogen have been replaced with univalent groups." ; oboInOwl:hasExactSynonym "azanium compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ammonium compounds" ; oboInOwl:id "CHEBI:35276" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ammonium compound" ; rdfs:subClassOf obo:CHEBI_51143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_35274 ] . obo:CHEBI_35287 obo:IAO_0000115 "A choline ester formed from choline and a carboxylic acid." ; chebi:charge "+1" ; chebi:formula "C6H13NO2R" ; chebi:mass "131.17290" ; chebi:monoisotopicmass "131.09463" ; chebi:smiles "C[N+](C)(C)CCOC([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13245", "CHEBI:22227", "CHEBI:2463" ; oboInOwl:hasDbXref "KEGG:C01777" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acylcholines", "an acylcholine" ; oboInOwl:id "CHEBI:35287" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acylcholine" ; rdfs:subClassOf obo:CHEBI_35267 . obo:CHEBI_35293 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fused compounds", "fused polycyclic compounds", "fused-ring polycyclic compound", "fused-ring polycyclic compounds", "polycyclic fused-ring compounds" ; oboInOwl:id "CHEBI:35293" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fused compound" ; rdfs:subClassOf obo:CHEBI_33635 . obo:CHEBI_35294 obo:IAO_0000115 "A polyclic compound in which all of the ring members are carbon atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbopolycyclic compounds" ; oboInOwl:id "CHEBI:35294" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbopolycyclic compound" ; rdfs:subClassOf obo:CHEBI_33598, obo:CHEBI_35295 . obo:CHEBI_35295 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "homopolycyclic compounds" ; oboInOwl:id "CHEBI:35295" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "homopolycyclic compound" ; rdfs:subClassOf obo:CHEBI_33597, obo:CHEBI_33635 . obo:CHEBI_35300 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ortho- and peri-fused polycyclic arenes" ; oboInOwl:id "CHEBI:35300" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ortho- and peri-fused polycyclic arene" ; rdfs:subClassOf obo:CHEBI_33639, obo:CHEBI_33848 . obo:CHEBI_35315 oboInOwl:hasExactSynonym "deoxy hexoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "deoxy hexosides" ; oboInOwl:id "CHEBI:35315" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "deoxy hexoside" ; rdfs:subClassOf obo:CHEBI_24400 . obo:CHEBI_3533 obo:IAO_0000115 "A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions." ; chebi:charge "0" ; chebi:formula "C28H38N2O4" ; chebi:inchi "InChI=1S/C28H38N2O4/c1-5-17-16-30-9-7-19-13-27(33-3)28(34-4)15-22(19)24(30)11-20(17)10-23-21-14-26(32-2)25(31)12-18(21)6-8-29-23/h12-15,17,20,23-24,29,31H,5-11,16H2,1-4H3/t17-,20-,23+,24-/m0/s1" ; chebi:inchikey "DTGZHCFJNDAHEN-OZEXIGSWSA-N" ; chebi:mass "466.61240" ; chebi:monoisotopicmass "466.28316" ; chebi:smiles "[H][C@]1(C[C@@]2([H])NCCc3cc(O)c(OC)cc23)C[C@]2([H])N(CCc3cc(OC)c(OC)cc23)C[C@@H]1CC" ; oboInOwl:hasDbXref "Beilstein:100615", "CAS:483-17-0", "KEGG:C09390", "KNApSAcK:C00001835", "LINCS:LSM-3808", "PMID:11411558", "PMID:11913711", "PMID:11996324", "PMID:12880315", "PMID:13437707", "PMID:18327911", "PMID:20061395", "PMID:20495341", "PMID:21228475", "PMID:2715231", "PMID:6716976", "Reaxys:100615" ; oboInOwl:hasExactSynonym "7',10,11-trimethoxyemetan-6'-ol", "Cephaeline" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cephaelin" ; oboInOwl:id "CHEBI:3533" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cephaeline" ; rdfs:subClassOf obo:CHEBI_61692, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_36380 ] . obo:CHEBI_35337 obo:IAO_0000115 "Any drug that enhances the activity of the central nervous system." ; oboInOwl:hasDbXref "Wikipedia:Central_nervous_system_stimulants" ; oboInOwl:hasExactSynonym "central nervous system stimulant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CNS stimulant", "analeptic", "analeptic agent", "analeptic drug", "analeptics", "central stimulant" ; oboInOwl:id "CHEBI:35337" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "central nervous system stimulant" ; rdfs:subClassOf obo:CHEBI_35470 . obo:CHEBI_35341 obo:IAO_0000115 "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." ; chebi:charge "0" ; chebi:formula "C19H31R" ; chebi:mass "259.450" ; chebi:monoisotopicmass "259.24258" ; chebi:smiles "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C" ; oboInOwl:hasAlternativeId "CHEBI:13687", "CHEBI:26768", "CHEBI:9263" ; oboInOwl:hasDbXref "KEGG:C00377", "MetaCyc:Steroids" ; oboInOwl:hasExactSynonym "Steroid", "steroids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a steroid" ; oboInOwl:id "CHEBI:35341" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "steroid" ; rdfs:subClassOf obo:CHEBI_18059, obo:CHEBI_51958 . obo:CHEBI_35350 oboInOwl:hasAlternativeId "CHEBI:24748", "CHEBI:5814" ; oboInOwl:hasDbXref "KEGG:C02159" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Hydroxysteroid", "hydroxy steroids", "hydroxysteroids" ; oboInOwl:id "CHEBI:35350" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_33822, obo:CHEBI_35341 . obo:CHEBI_35352 obo:IAO_0000115 "Any heteroorganic entity containing at least one carbon-nitrogen bond." ; oboInOwl:hasExactSynonym "organonitrogen compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organonitrogens" ; oboInOwl:id "CHEBI:35352" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organonitrogen compound" ; rdfs:subClassOf obo:CHEBI_33285, obo:CHEBI_51143 . obo:CHEBI_35356 obo:IAO_0000115 "An imide in which the two acyl substituents on nitrogen are carboacyl groups." ; chebi:charge "0" ; chebi:formula "C2NO2R3" ; chebi:mass "70.027" ; chebi:monoisotopicmass "69.99290" ; chebi:smiles "[*]N(C([*])=O)C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dicarboximides" ; oboInOwl:id "CHEBI:35356" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dicarboximide" ; rdfs:subClassOf obo:CHEBI_24782 . obo:CHEBI_35366 obo:IAO_0000115 "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids." ; chebi:charge "0" ; chebi:formula "CHO2R" ; chebi:mass "45.01740" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "OC([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13633", "CHEBI:24024", "CHEBI:4984" ; oboInOwl:hasDbXref "KEGG:C00162", "PMID:14287444", "PMID:14300208", "PMID:14328676", "Wikipedia:Fatty_acid" ; oboInOwl:hasExactSynonym "Fatty acid", "fatty acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Fettsaeure", "Fettsaeuren", "acide gras", "acides gras", "acido graso", "acidos grasos", "fatty acids" ; oboInOwl:id "CHEBI:35366" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fatty acid" ; rdfs:subClassOf obo:CHEBI_18059, obo:CHEBI_25384, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_28868 ] . obo:CHEBI_35367 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "thiocarboxylates", "thiocarboxylic acid anions" ; oboInOwl:id "CHEBI:35367" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "thiocarboxylic acid anion" ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_35381 obo:IAO_0000115 "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." ; oboInOwl:hasAlternativeId "CHEBI:25407", "CHEBI:6984" ; oboInOwl:hasDbXref "KEGG:C06698" ; oboInOwl:hasExactSynonym "Monosaccharide", "monosaccharides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Monosaccharid", "Monosacharid", "monosacarido", "monosacaridos" ; oboInOwl:id "CHEBI:35381" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monosaccharide" ; rdfs:subClassOf obo:CHEBI_16646 . obo:CHEBI_35406 obo:IAO_0000115 "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." ; oboInOwl:hasAlternativeId "CHEBI:33274", "CHEBI:33436" ; oboInOwl:hasExactSynonym "oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoacid anions", "oxoanions" ; oboInOwl:id "CHEBI:35406" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxoanion" ; rdfs:subClassOf obo:CHEBI_25741, obo:CHEBI_33273 . obo:CHEBI_35441 obo:IAO_0000115 "A substance used in the prophylaxis or therapy of infectious diseases." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-infective agents", "anti-infective drugs", "antiinfective agents", "antiinfective drug" ; oboInOwl:id "CHEBI:35441" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antiinfective agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35442 obo:IAO_0000115 "A substance used to treat or prevent parasitic infections." ; oboInOwl:hasDbXref "Wikipedia:Antiparasitic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antiparasitic drugs", "antiparasitics", "parasiticides" ; oboInOwl:id "CHEBI:35442" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antiparasitic agent" ; rdfs:subClassOf obo:CHEBI_35441 . obo:CHEBI_35443 obo:IAO_0000115 "Substance intended to kill parasitic worms (helminths)." ; oboInOwl:hasExactSynonym "anthelminthic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anthelminthics", "anthelmintic", "anthelmintics", "antihelminth", "antihelmintico", "vermifuge" ; oboInOwl:id "CHEBI:35443" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anthelminthic drug" ; rdfs:subClassOf obo:CHEBI_35442 . obo:CHEBI_35444 obo:IAO_0000115 "A substance used in the treatment or control of nematode infestations." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antinematodal agent", "antinematodal drugs", "antinematodals" ; oboInOwl:id "CHEBI:35444" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antinematodal drug" ; rdfs:subClassOf obo:CHEBI_25491, obo:CHEBI_35443 . obo:CHEBI_35469 obo:IAO_0000115 "Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antidepressant drugs", "antidepressants", "thymoanaleptics", "thymoleptic drugs", "thymoleptics" ; oboInOwl:id "CHEBI:35469" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antidepressant" ; rdfs:subClassOf obo:CHEBI_35471 . obo:CHEBI_35470 obo:IAO_0000115 "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CNS agent", "CNS drugs", "central nervous system agents" ; oboInOwl:id "CHEBI:35470" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "central nervous system drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35471 obo:IAO_0000115 "A loosely defined grouping of drugs that have effects on psychological function." ; oboInOwl:hasDbXref "Wikipedia:Psychotropic_drug" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "psychoactive agent", "psychoactive drugs", "psychopharmaceuticals", "psychotropic drugs" ; oboInOwl:id "CHEBI:35471" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "psychotropic drug" ; rdfs:subClassOf obo:CHEBI_35470 . obo:CHEBI_35472 obo:IAO_0000115 "A substance that reduces or suppresses inflammation." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-inflammatory drugs", "antiinflammatory agent", "antiinflammatory drug", "antiinflammatory drugs" ; oboInOwl:id "CHEBI:35472" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anti-inflammatory drug" ; rdfs:subClassOf obo:CHEBI_23888, obo:CHEBI_67079 . obo:CHEBI_35473 obo:IAO_0000115 "A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ataractics", "tranquilising drug", "tranquilizing drugs", "tranquillising agent", "tranquillizing agents" ; oboInOwl:id "CHEBI:35473" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tranquilizing drug" ; rdfs:subClassOf obo:CHEBI_35471, obo:CHEBI_35488 . obo:CHEBI_35474 obo:IAO_0000115 "Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-anxiety agents", "anti-anxiety drugs", "anxiolytic agents", "anxiolytics", "minor tranquilisers", "minor tranquilizers", "minor tranquilizing agents" ; oboInOwl:id "CHEBI:35474" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anxiolytic drug" ; rdfs:subClassOf obo:CHEBI_35473 . obo:CHEBI_35476 obo:IAO_0000115 "Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Neuroleptikum", "antipsychotic agents", "antipsychotic drug", "antipsychotic drugs", "antipsychotics", "antipsychotiques", "grosser Tranquilizer", "major tranquilizers", "major tranquilizing agents", "neuroleptic", "neuroleptic agents", "neuroleptics", "neuroleptique", "neuroleptiques" ; oboInOwl:id "CHEBI:35476" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antipsychotic agent" ; rdfs:subClassOf obo:CHEBI_35473 . obo:CHEBI_35479 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkali metal salts" ; oboInOwl:id "CHEBI:35479" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkali metal salt" ; rdfs:subClassOf obo:CHEBI_24866, obo:CHEBI_33296 . obo:CHEBI_35480 obo:IAO_0000115 "An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35480" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "analgesic" ; rdfs:subClassOf obo:CHEBI_23888, obo:CHEBI_52210 . obo:CHEBI_35481 obo:IAO_0000115 "A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35481" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "non-narcotic analgesic" ; rdfs:subClassOf obo:CHEBI_35480 . obo:CHEBI_35488 obo:IAO_0000115 "A loosely defined group of drugs that tend to reduce the activity of the central nervous system." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CNS depressants", "central nervous system depressants" ; oboInOwl:id "CHEBI:35488" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "central nervous system depressant" ; rdfs:subClassOf obo:CHEBI_35470 . obo:CHEBI_35498 obo:IAO_0000115 "An agent that promotes the excretion of urine through its effects on kidney function." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "diuretics" ; oboInOwl:id "CHEBI:35498" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diuretic" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35506 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkaloid fundamental parents" ; oboInOwl:id "CHEBI:35506" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35507 . obo:CHEBI_35507 oboInOwl:hasExactSynonym "natural product fundamental parents" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35507" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "natural product fundamental parent" ; rdfs:subClassOf obo:CHEBI_33245 . obo:CHEBI_35508 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "steroid fundamental parents" ; oboInOwl:id "CHEBI:35508" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "steroid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35341, obo:CHEBI_35507 . obo:CHEBI_35519 chebi:charge "0" ; chebi:formula "C24H42" ; chebi:inchi "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18?,19+,20-,21+,22+,23+,24-/m1/s1" ; chebi:inchikey "QSHQKIURKJITMZ-BRPMRXRMSA-N" ; chebi:mass "330.59028" ; chebi:monoisotopicmass "330.32865" ; chebi:smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC" ; oboInOwl:hasExactSynonym "cholane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35519" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cholane" ; rdfs:subClassOf obo:CHEBI_35508 . obo:CHEBI_35522 obo:IAO_0000115 "An agent that selectively binds to and activates beta-adrenergic receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "beta-adrenergic agonists", "beta-adrenergic receptor agonist", "beta-adrenoceptor agonists" ; oboInOwl:id "CHEBI:35522" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "beta-adrenergic agonist" ; rdfs:subClassOf obo:CHEBI_37886, obo:CHEBI_48540 . obo:CHEBI_35524 obo:IAO_0000115 "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sympathomimetic", "sympathomimetics" ; oboInOwl:id "CHEBI:35524" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sympathomimetic agent" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_35545 chebi:charge "0" ; chebi:formula "C10H8N2" ; chebi:mass "156.184" ; chebi:monoisotopicmass "156.06875" ; oboInOwl:hasExactSynonym "bipyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bipyridin", "bipyridyl" ; oboInOwl:id "CHEBI:35545" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bipyridine" ; rdfs:subClassOf obo:CHEBI_50511 . obo:CHEBI_35552 oboInOwl:hasExactSynonym "heterocyclic parent hydrides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterocyclic fundamental parent", "heterocyclic organic fundamental parents", "organic heterocyclic fundamental parents" ; oboInOwl:id "CHEBI:35552" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heterocyclic organic fundamental parent" ; rdfs:subClassOf obo:CHEBI_33245 . obo:CHEBI_35554 obo:IAO_0000115 "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cardiovascular agent", "cardiovascular drugs" ; oboInOwl:id "CHEBI:35554" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cardiovascular drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35555 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude organic heteromonocyclic parents", "mancude-ring organic heteromonocyclic parents" ; oboInOwl:id "CHEBI:35555" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mancude organic heteromonocyclic parent" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_35571 . obo:CHEBI_35568 obo:IAO_0000115 "Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds." ; oboInOwl:hasExactSynonym "mancude-ring systems" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude rings", "mancunide-ring systems" ; oboInOwl:id "CHEBI:35568" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mancude ring" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_35569 obo:IAO_0000115 "An agent that selectively binds to and activates alpha-adrenergic receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-adrenergic agonists", "alpha-adrenergic receptor agonist", "alpha-adrenoceptor agonists" ; oboInOwl:id "CHEBI:35569" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-adrenergic agonist" ; rdfs:subClassOf obo:CHEBI_37886, obo:CHEBI_48539 . obo:CHEBI_35570 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude organic heterobicyclic parents", "mancude-ring organic heterobicyclic parents" ; oboInOwl:id "CHEBI:35570" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mancude organic heterobicyclic parent" ; rdfs:subClassOf obo:CHEBI_27171, obo:CHEBI_35571 . obo:CHEBI_35571 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude organic heterocyclic parents", "mancude-ring organic heterocyclic parents" ; oboInOwl:id "CHEBI:35571" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mancude organic heterocyclic parent" ; rdfs:subClassOf obo:CHEBI_35552, obo:CHEBI_35573 . obo:CHEBI_35573 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic mancude parents", "organic mancude-ring parents" ; oboInOwl:id "CHEBI:35573" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic mancude parent" ; rdfs:subClassOf obo:CHEBI_33245, obo:CHEBI_35568 . obo:CHEBI_35584 obo:IAO_0000115 "A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:mass "120.112" ; chebi:monoisotopicmass "120.04360" ; oboInOwl:hasDbXref "HMDB:HMDB0001366", "KEGG:C15587", "MetaCyc:PURINE", "PMID:12865945", "PMID:24088627" ; oboInOwl:hasExactSynonym "purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35584" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine" ; rdfs:subClassOf obo:CHEBI_26401, obo:CHEBI_35570, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ] . obo:CHEBI_35586 obo:IAO_0000115 "The 1H-tautomer of purine." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" ; chebi:inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" ; chebi:mass "120.11210" ; chebi:monoisotopicmass "120.04360" ; chebi:smiles "c1nc2c[nH]cnc2n1" ; oboInOwl:hasDbXref "Gmelin:2379911" ; oboInOwl:hasExactSynonym "1H-purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35586" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "1H-purine" ; rdfs:subClassOf obo:CHEBI_35584, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17258 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35588 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_35588 obo:IAO_0000115 "The 3H-tautomer of purine." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" ; chebi:inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" ; chebi:mass "120.11222" ; chebi:monoisotopicmass "120.04360" ; chebi:smiles "c1nc2cnc[nH]c2n1" ; oboInOwl:hasDbXref "PMID:6149478", "PMID:7178185", "PMID:7296170", "Reaxys:1210196" ; oboInOwl:hasExactSynonym "3H-purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35588" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "3H-purine" ; rdfs:subClassOf obo:CHEBI_35584, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17258 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35586 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_35589 obo:IAO_0000115 "The 9H-tautomer of purine." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" ; chebi:inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" ; chebi:mass "120.11222" ; chebi:monoisotopicmass "120.04360" ; chebi:smiles "c1ncc2nc[nH]c2n1" ; oboInOwl:hasDbXref "Beilstein:606899", "CAS:120-73-0", "Gmelin:3120", "Wikipedia:Purine" ; oboInOwl:hasExactSynonym "9H-purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35589" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "9H-purine" ; rdfs:subClassOf obo:CHEBI_35584, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17258 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35586 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35588 ] . obo:CHEBI_35604 obo:IAO_0000115 "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." ; oboInOwl:hasExactSynonym "carbon oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon oxoanions", "oxocarbon anion", "oxocarbon anions" ; oboInOwl:id "CHEBI:35604" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbon oxoanion" ; rdfs:subClassOf obo:CHEBI_25696, obo:CHEBI_35406, obo:CHEBI_36963 . obo:CHEBI_35605 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon oxoacids", "oxoacids of carbon" ; oboInOwl:id "CHEBI:35605" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbon oxoacid" ; rdfs:subClassOf obo:CHEBI_24833, obo:CHEBI_36963 . obo:CHEBI_35610 obo:IAO_0000115 "A substance that inhibits or prevents the proliferation of neoplasms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anticancer agent", "anticancer agents", "antineoplastic", "antineoplastic agents", "cytostatic" ; oboInOwl:id "CHEBI:35610" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antineoplastic agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35618 obo:IAO_0000115 "Any ether in which the oxygen is attached to at least one aryl substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35618" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aromatic ether" ; rdfs:subClassOf obo:CHEBI_25698, obo:CHEBI_33659 . obo:CHEBI_35620 obo:IAO_0000115 "A drug used to cause dilation of the blood vessels." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "vasodilator", "vasodilator agents" ; oboInOwl:id "CHEBI:35620" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "vasodilator agent" ; rdfs:subClassOf obo:CHEBI_35554 . obo:CHEBI_35623 obo:IAO_0000115 "A drug used to prevent seizures or reduce their severity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Antiepileptika", "Antiepileptikum", "Antikonvulsiva", "Antikonvulsivum", "anti-convulsant", "anti-convulsants", "anti-convulsive agent", "anti-convulsive agents", "anticonvulsants", "anticonvulsive agent", "anticonvulsive agents", "antiepileptic", "antiepileptics", "antiepileptique", "antiepileptiques" ; oboInOwl:id "CHEBI:35623" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anticonvulsant" ; rdfs:subClassOf obo:CHEBI_35488 . obo:CHEBI_35640 obo:IAO_0000115 "Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ARI", "NERI", "NRI", "adrenergic reuptake inhibitor", "adrenergic reuptake inhibitors", "adrenergic uptake inhibitors", "norepinephrine reuptake inhibitor", "norepinephrine reuptake inhibitors" ; oboInOwl:id "CHEBI:35640" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adrenergic uptake inhibitor" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_35662 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "terpenoid fundamental parents" ; oboInOwl:id "CHEBI:35662" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "terpenoid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35507 . obo:CHEBI_35678 obo:IAO_0000115 "A drug that binds to and activates histamine receptors. Although they have been suggested for a variety of clinical applications, histamine agonists have so far been more widely used in research than therapeutically." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "histamine agonists" ; oboInOwl:id "CHEBI:35678" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "histamine agonist" ; rdfs:subClassOf obo:CHEBI_37957 . obo:CHEBI_35681 obo:IAO_0000115 "A secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it." ; chebi:charge "0" ; chebi:formula "CH2OR2" ; chebi:mass "30.026" ; chebi:monoisotopicmass "30.01056" ; chebi:smiles "*C(*)O" ; oboInOwl:hasAlternativeId "CHEBI:13425", "CHEBI:13686", "CHEBI:26617", "CHEBI:58662", "CHEBI:8741", "CHEBI:9077" ; oboInOwl:hasDbXref "KEGG:C00432", "KEGG:C01612" ; oboInOwl:hasExactSynonym "Secondary alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "R-CHOH-R'", "a secondary alcohol", "secondary alcohols" ; oboInOwl:id "CHEBI:35681" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "secondary alcohol" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_35683 obo:IAO_0000115 "Any organic sulfide in which the sulfur is attached to at least one aromatic group." ; oboInOwl:hasExactSynonym "aryl sulfide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aryl sulfides" ; oboInOwl:id "CHEBI:35683" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aryl sulfide" ; rdfs:subClassOf obo:CHEBI_16385 . obo:CHEBI_35692 obo:IAO_0000115 "Any carboxylic acid containing two carboxy groups." ; oboInOwl:hasAlternativeId "CHEBI:23692", "CHEBI:36172", "CHEBI:4501" ; oboInOwl:hasDbXref "KEGG:C02028" ; oboInOwl:hasExactSynonym "Dicarboxylic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dicarboxylic acids" ; oboInOwl:id "CHEBI:35692" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dicarboxylic acid" ; rdfs:subClassOf obo:CHEBI_131927, obo:CHEBI_33575, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_35693 ] . obo:CHEBI_35693 oboInOwl:hasExactSynonym "dicarboxylic acid anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dicarboxylic acid anions" ; oboInOwl:id "CHEBI:35693" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dicarboxylic acid anion" ; rdfs:subClassOf obo:CHEBI_29067, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35692 ] . obo:CHEBI_35701 obo:IAO_0000115 "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." ; oboInOwl:hasAlternativeId "CHEBI:23960", "CHEBI:4859" ; oboInOwl:hasDbXref "KEGG:C00287", "Wikipedia:Ester" ; oboInOwl:hasExactSynonym "Ester" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "esters" ; oboInOwl:id "CHEBI:35701" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ester" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_35702 obo:IAO_0000115 "An ether in which the oxygen atom is linked to two ethyl groups." ; chebi:charge "0" ; chebi:formula "C4H10O" ; chebi:inchi "InChI=1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3" ; chebi:inchikey "RTZKZFJDLAIYFH-UHFFFAOYSA-N" ; chebi:mass "74.12160" ; chebi:monoisotopicmass "74.07316" ; chebi:smiles "CCOCC" ; oboInOwl:hasAlternativeId "CHEBI:23991", "CHEBI:31565" ; oboInOwl:hasDbXref "Beilstein:1696894", "CAS:60-29-7", "Drug_Central:4417", "Gmelin:25444", "KEGG:C13240", "KEGG:D01772", "PMID:24443836", "Reaxys:1696894", "Wikipedia:Diethyl_ether" ; oboInOwl:hasExactSynonym "1,1'-oxydiethane", "Diethyl ether" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1'-oxybisethane", "3-oxapentane", "Aether", "Anesthetic ether", "Diethylaether", "Ether", "Pronarcol", "R-610", "aether", "aether pro narcosi", "diethyl oxide", "ethoxyethane", "ethyl ether", "ethyl oxide" ; oboInOwl:id "CHEBI:35702" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diethyl ether" ; rdfs:subClassOf obo:CHEBI_134179, obo:CHEBI_25698, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38870 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48355 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_35703 obo:IAO_0000115 "A xenobiotic (Greek, xenos \"foreign\"; bios \"life\") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means." ; oboInOwl:hasAlternativeId "CHEBI:10074", "CHEBI:27333" ; oboInOwl:hasDbXref "KEGG:C06708", "Wikipedia:Xenobiotic" ; oboInOwl:hasExactSynonym "Xenobiotic", "xenobiotic", "xenobiotics" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "xenobiotic compounds" ; oboInOwl:id "CHEBI:35703" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "xenobiotic" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_35705 obo:IAO_0000115 "An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "immunosuppressant", "immunosuppressive agents", "inmunosupresor" ; oboInOwl:id "CHEBI:35705" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "immunosuppressive agent" ; rdfs:subClassOf obo:CHEBI_50846 . obo:CHEBI_35717 obo:IAO_0000115 "A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hypnotics", "hypnotics and sedatives", "sedative drug", "sedatives", "sedatives and hypnotics" ; oboInOwl:id "CHEBI:35717" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sedative" ; rdfs:subClassOf obo:CHEBI_35488 . obo:CHEBI_35718 obo:IAO_0000115 "An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antifungal", "antifungal agents", "antifungal drug", "antifungal drugs", "antifungals" ; oboInOwl:id "CHEBI:35718" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antifungal agent" ; rdfs:subClassOf obo:CHEBI_33281 . obo:CHEBI_35722 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glycosaminoglycan sulfate", "glycosaminoglycan sulfates", "sulfated glycosaminoglycans" ; oboInOwl:id "CHEBI:35722" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfated glycosaminoglycan" ; rdfs:subClassOf obo:CHEBI_18085, obo:CHEBI_35724 . obo:CHEBI_35724 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrate sulfates", "carbohydrate sulphates" ; oboInOwl:id "CHEBI:35724" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbohydrate sulfate" ; rdfs:subClassOf obo:CHEBI_25704, obo:CHEBI_26819, obo:CHEBI_63299 . obo:CHEBI_35737 obo:IAO_0000115 "Compounds in which one oxygen of a carboxy group has been replaced by divalent sulfur; RC(=O)SH or RC(=S)OH." ; oboInOwl:hasExactSynonym "monothiocarboxylic acid", "monothiocarboxylic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monothiocarboxylic acids", "thio acid" ; oboInOwl:id "CHEBI:35737" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monothiocarboxylic acid" ; rdfs:subClassOf obo:CHEBI_33307 . obo:CHEBI_35741 obo:IAO_0000115 "Any member of the group of lipids containing a common glycerol backbone to which at least one fatty acid-derived group is attached." ; oboInOwl:hasDbXref "PMID:18606873" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glycerolipids" ; oboInOwl:id "CHEBI:35741" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycerolipid" ; rdfs:subClassOf obo:CHEBI_18059, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17754 ] . obo:CHEBI_35757 obo:IAO_0000115 "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.01000" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13657", "CHEBI:25382", "CHEBI:3407" ; oboInOwl:hasDbXref "KEGG:C00060" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Carboxylate", "Monocarboxylate", "a monocarboxylate", "monocarboxylates", "monocarboxylic acid anions" ; oboInOwl:id "CHEBI:35757" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monocarboxylic acid anion" ; rdfs:subClassOf obo:CHEBI_29067, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_25384 ] . obo:CHEBI_35776 oboInOwl:hasExactSynonym "arsenic oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "arsenic oxoanions", "oxoanions of arsenic" ; oboInOwl:id "CHEBI:35776" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "arsenic oxoanion" ; rdfs:subClassOf obo:CHEBI_22632, obo:CHEBI_33459 . obo:CHEBI_35780 obo:IAO_0000115 "A phosphorus oxoanion that is the conjugate base of phosphoric acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Pi", "phosphate", "phosphate ions" ; oboInOwl:id "CHEBI:35780" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphate ion" ; rdfs:subClassOf obo:CHEBI_33461, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_26078 ] . obo:CHEBI_35790 obo:IAO_0000115 "An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom." ; oboInOwl:hasExactSynonym "oxazole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxazoles" ; oboInOwl:id "CHEBI:35790" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxazole" ; rdfs:subClassOf obo:CHEBI_38104, obo:CHEBI_68452 . obo:CHEBI_35820 obo:IAO_0000115 "Any antimicrobial drug which is used to treat or prevent protozoal infections." ; oboInOwl:hasDbXref "Wikipedia:Antiprotozoal_agent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antiprotozoal agent", "antiprotozoal agents", "antiprotozoal drugs" ; oboInOwl:id "CHEBI:35820" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antiprotozoal drug" ; rdfs:subClassOf obo:CHEBI_35442, obo:CHEBI_36043 . obo:CHEBI_35842 obo:IAO_0000115 "A drug used to treat rheumatoid arthritis." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-rheumatic drugs", "antirheumatic agent", "antirheumatic drugs" ; oboInOwl:id "CHEBI:35842" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antirheumatic drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35845 obo:IAO_0000115 "A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gout suppressants" ; oboInOwl:id "CHEBI:35845" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "gout suppressant" ; rdfs:subClassOf obo:CHEBI_35842 . obo:CHEBI_35875 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "imidazopyrimidines" ; oboInOwl:id "CHEBI:35875" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "imidazopyrimidine" ; rdfs:subClassOf obo:CHEBI_27171, obo:CHEBI_33833, obo:CHEBI_38101 . obo:CHEBI_35881 oboInOwl:hasExactSynonym "pnictogen hydride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pnictogen hydrides" ; oboInOwl:id "CHEBI:35881" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pnictogen hydride" ; rdfs:subClassOf obo:CHEBI_33242, obo:CHEBI_33302 . obo:CHEBI_35939 obo:IAO_0000115 "A pentenoic acid having the double bond at position 2." ; chebi:charge "0" ; chebi:formula "C5H8O2" ; chebi:inchi "InChI=1S/C5H8O2/c1-2-3-4-5(6)7/h3-4H,2H2,1H3,(H,6,7)" ; chebi:inchikey "YIYBQIKDCADOSF-UHFFFAOYSA-N" ; chebi:mass "100.11582" ; chebi:monoisotopicmass "100.05243" ; chebi:smiles "[H]C(CC)=CC(O)=O" ; oboInOwl:hasDbXref "CAS:626-98-2", "LIPID_MAPS_instance:LMFA01030005", "Reaxys:1720310" ; oboInOwl:hasExactSynonym "pent-2-enoic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-pentenoic acid", "C5:1, n-3", "Pent-2-ensaeure", "Propylidenessigsaeure", "alpha-Butylen-alpha-carbonsaeure", "alpha-pentenoic acid", "alpha.beta-Pentensaeure", "beta-Aethyl-acrylsaeure", "beta-Aethylacrylsaeure", "beta-ethyl acrylic acid" ; oboInOwl:id "CHEBI:35939" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pent-2-enoic acid" ; rdfs:subClassOf obo:CHEBI_25897, obo:CHEBI_79020 . obo:CHEBI_35942 obo:IAO_0000115 "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "neurotransmitter agents" ; oboInOwl:id "CHEBI:35942" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "neurotransmitter agent" ; rdfs:subClassOf obo:CHEBI_23888, obo:CHEBI_52210 . obo:CHEBI_35987 obo:IAO_0000115 "Any amino acid carrying two amino groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35987" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diamino acid" ; rdfs:subClassOf obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_59561 ] . obo:CHEBI_36043 obo:IAO_0000115 "A drug used to treat or prevent microbial infections." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimicrobial drugs" ; oboInOwl:id "CHEBI:36043" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimicrobial drug" ; rdfs:subClassOf obo:CHEBI_33281, obo:CHEBI_35441 . obo:CHEBI_36078 oboInOwl:hasAlternativeId "CHEBI:22867", "CHEBI:50419" ; oboInOwl:hasDbXref "LIPID_MAPS_class:LMST04" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bile acids and derivatives", "cholanoids" ; oboInOwl:id "CHEBI:36078" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cholanoid" ; rdfs:subClassOf obo:CHEBI_35341, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_35519 ] . obo:CHEBI_36080 obo:IAO_0000115 "A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome." ; oboInOwl:hasAlternativeId "CHEBI:13677", "CHEBI:14911" ; oboInOwl:hasExactSynonym "proteins" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36080" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "protein" ; rdfs:subClassOf obo:PR_000000001 ; owl:equivalentClass obo:PR_000000001 . obo:CHEBI_36093 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic chloride salt", "inorganic chloride salts", "inorganic chlorides" ; oboInOwl:id "CHEBI:36093" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic chloride" ; rdfs:subClassOf obo:CHEBI_23114, obo:CHEBI_24839 . obo:CHEBI_36235 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bile acid anions" ; oboInOwl:id "CHEBI:36235" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bile acid anion" ; rdfs:subClassOf obo:CHEBI_35757, obo:CHEBI_50160 . obo:CHEBI_36237 obo:IAO_0000115 "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24." ; chebi:charge "0" ; chebi:formula "C24H40O2" ; chebi:inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17?,18+,19-,20+,21+,23+,24-/m1/s1" ; chebi:inchikey "RPKLZQLYODPWTM-KBMWBBLPSA-N" ; chebi:mass "360.57320" ; chebi:monoisotopicmass "360.30283" ; chebi:smiles "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O" ; oboInOwl:hasDbXref "CAS:25312-65-6", "Patent:JP2008069152", "Reaxys:13246008" ; oboInOwl:hasExactSynonym "cholan-24-oic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36237" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cholanic acid" ; rdfs:subClassOf obo:CHEBI_36278 . obo:CHEBI_36238 chebi:charge "0" ; chebi:formula "C24H40O2" ; chebi:inchi "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1" ; chebi:inchikey "RPKLZQLYODPWTM-LVVAJZGHSA-N" ; chebi:mass "360.57320" ; chebi:monoisotopicmass "360.30283" ; chebi:smiles "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC(O)=O" ; oboInOwl:hasDbXref "Beilstein:3214794", "CAS:546-18-9", "LIPID_MAPS_instance:LMST04010441" ; oboInOwl:hasExactSynonym "5beta-cholan-24-oic acid", "5beta-cholanic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(5beta)-cholan-24-oic acid", "(5beta,17beta)-gamma-methylandrostane-17-butanoic acid", "5beta-cholanoic acid", "ursocholanic acid" ; oboInOwl:id "CHEBI:36238" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "5beta-cholanic acid" ; rdfs:subClassOf obo:CHEBI_36237, obo:CHEBI_36248 . obo:CHEBI_36248 obo:IAO_0000115 "Members of the class of cholanic acids based on a 5beta-cholane skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36248" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "5beta-cholanic acids" ; rdfs:subClassOf obo:CHEBI_136889, obo:CHEBI_36278, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_20664 ] . obo:CHEBI_36277 obo:IAO_0000115 "A salt of a bile acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bile acid salts" ; oboInOwl:id "CHEBI:36277" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bile acid salt" ; rdfs:subClassOf obo:CHEBI_24868, obo:CHEBI_36078 . obo:CHEBI_36278 oboInOwl:hasAlternativeId "CHEBI:23166", "CHEBI:23211" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36278" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "cholanic acids" ; rdfs:subClassOf obo:CHEBI_36078, obo:CHEBI_47891 . obo:CHEBI_36309 oboInOwl:hasExactSynonym "macrocyclic tetrapyrroles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic tetrapyrroles", "macrocyclic tetrapyrrole" ; oboInOwl:id "CHEBI:36309" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic tetrapyrrole" ; rdfs:subClassOf obo:CHEBI_26932, obo:CHEBI_47882 . obo:CHEBI_36315 obo:IAO_0000115 "Any glycerophospholipid having the polar alcohol inositol esterified to the phosphate group at the sn-3 position of the glycerol backbone." ; oboInOwl:hasAlternativeId "CHEBI:26040", "CHEBI:35770" ; oboInOwl:hasDbXref "PMID:14706866" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "GPI", "glycerophosphoinositols" ; oboInOwl:id "CHEBI:36315" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycerophosphoinositol" ; rdfs:subClassOf obo:CHEBI_37739, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_24848 ] . obo:CHEBI_36338 obo:IAO_0000115 "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "leptons" ; oboInOwl:id "CHEBI:36338" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "lepton" ; rdfs:subClassOf obo:CHEBI_33233, obo:CHEBI_36340 . obo:CHEBI_36339 obo:IAO_0000115 "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "baryons" ; oboInOwl:id "CHEBI:36339" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "baryon" ; rdfs:subClassOf obo:CHEBI_36340, obo:CHEBI_36344 . obo:CHEBI_36340 obo:IAO_0000115 "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." ; oboInOwl:hasExactSynonym "fermion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fermions" ; oboInOwl:id "CHEBI:36340" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fermion" ; rdfs:subClassOf obo:CHEBI_36342 . obo:CHEBI_36341 obo:IAO_0000115 "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose." ; oboInOwl:hasExactSynonym "boson" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bosons" ; oboInOwl:id "CHEBI:36341" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "boson" ; rdfs:subClassOf obo:CHEBI_36342 . obo:CHEBI_36342 obo:IAO_0000115 "A particle smaller than an atom." ; oboInOwl:hasDbXref "Wikipedia:Subatomic_particle" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "subatomic particles" ; oboInOwl:id "CHEBI:36342" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "subatomic particle" . obo:CHEBI_36343 obo:IAO_0000115 "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "composite particles" ; oboInOwl:id "CHEBI:36343" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "composite particle" ; rdfs:subClassOf obo:CHEBI_36342 . obo:CHEBI_36344 obo:IAO_0000115 "Hadron is a subatomic particle which experiences the strong force." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hadrons" ; oboInOwl:id "CHEBI:36344" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hadron" ; rdfs:subClassOf obo:CHEBI_36343 . obo:CHEBI_36347 obo:IAO_0000115 "A nucleus or any of its constituents in any of their energy states." ; oboInOwl:hasExactSynonym "nuclear particle" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36347" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nuclear particle" ; rdfs:subClassOf obo:CHEBI_36342 . obo:CHEBI_36357 obo:IAO_0000115 "Any molecular entity consisting of more than one atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic entities" ; oboInOwl:id "CHEBI:36357" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polyatomic entity" ; rdfs:subClassOf obo:CHEBI_23367, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_24433 ] . obo:CHEBI_36358 obo:IAO_0000115 "An ion consisting of more than one atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic ions" ; oboInOwl:id "CHEBI:36358" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polyatomic ion" ; rdfs:subClassOf obo:CHEBI_24870, obo:CHEBI_36357 . obo:CHEBI_36359 oboInOwl:hasExactSynonym "phosphorus oxoacid derivative" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36359" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphorus oxoacid derivative" ; rdfs:subClassOf obo:CHEBI_33241, obo:CHEBI_36360, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33457 ] . obo:CHEBI_36360 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36360" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "phosphorus oxoacids and derivatives" ; rdfs:subClassOf obo:CHEBI_26082 . obo:CHEBI_3638 obo:IAO_0000115 "An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis." ; chebi:charge "0" ; chebi:formula "C18H26ClN3" ; chebi:inchi "InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)" ; chebi:inchikey "WHTVZRBIWZFKQO-UHFFFAOYSA-N" ; chebi:mass "319.87200" ; chebi:monoisotopicmass "319.18153" ; chebi:smiles "CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12" ; oboInOwl:hasDbXref "Beilstein:482809", "CAS:54-05-7", "DrugBank:DB00608", "Drug_Central:607", "Gmelin:781126", "HMDB:HMDB0014746", "KEGG:C07625", "KEGG:D02366", "LINCS:LSM-1901", "PDBeChem:CLQ", "PMID:11198399", "PMID:17594118", "PMID:18052874", "PMID:19426658", "PMID:23288916", "PMID:23580861", "PMID:23635029", "PMID:23644906", "PMID:23706562", "PMID:23852712", "PMID:23891850", "PMID:25285162", "Patent:DE683692", "Patent:US2233970", "Reaxys:482809", "Wikipedia:Chloroquine" ; oboInOwl:hasExactSynonym "Chloroquine", "N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aralen", "Artrichin", "Bemaphate", "Capquin", "Chlorochin", "N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine", "Nivaquine B", "Resoquine", "Reumachlor", "Sanoquin", "chloroquine", "chloroquinum", "cloroquina" ; oboInOwl:id "CHEBI:3638" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chloroquine" ; rdfs:subClassOf obo:CHEBI_36683, obo:CHEBI_36709, obo:CHEBI_50995, obo:CHEBI_50996, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149553 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35842 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50177 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_88230 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_149484 ] . obo:CHEBI_36380 chebi:charge "0" ; chebi:formula "C25H32N2" ; chebi:inchi "InChI=1S/C25H32N2/c1-2-18-17-27-14-12-20-8-4-6-10-23(20)25(27)16-21(18)15-24-22-9-5-3-7-19(22)11-13-26-24/h3-10,18,21,24-26H,2,11-17H2,1H3/t18-,21-,24+,25-/m0/s1" ; chebi:inchikey "KSQYVPHTTWSOHG-CKBKHPSWSA-N" ; chebi:mass "360.53506" ; chebi:monoisotopicmass "360.25655" ; chebi:smiles "[H][C@]1(C[C@@]2([H])NCCc3ccccc23)C[C@]2([H])N(CCc3ccccc23)C[C@@H]1CC" ; oboInOwl:hasExactSynonym "emetan" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36380" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "emetan" ; rdfs:subClassOf obo:CHEBI_24921, obo:CHEBI_24922, obo:CHEBI_38515 . obo:CHEBI_36416 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude organic heterotricyclic parents", "mancude-ring organic heterotricyclic parents" ; oboInOwl:id "CHEBI:36416" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mancude organic heterotricyclic parent" ; rdfs:subClassOf obo:CHEBI_26979, obo:CHEBI_35571 . obo:CHEBI_36586 obo:IAO_0000115 "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." ; oboInOwl:hasExactSynonym "carbonyl compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36586" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbonyl compound" ; rdfs:subClassOf obo:CHEBI_36587, obo:CHEBI_36963, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_23019 ] . obo:CHEBI_36587 obo:IAO_0000115 "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." ; oboInOwl:hasExactSynonym "oxo compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic oxo compounds" ; oboInOwl:id "CHEBI:36587" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic oxo compound" ; rdfs:subClassOf obo:CHEBI_72695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_46629 ] . obo:CHEBI_36683 obo:IAO_0000115 "An organochlorine compound is a compound containing at least one carbon-chlorine bond." ; chebi:charge "0" ; chebi:formula "ClR" ; chebi:mass "35.453" ; chebi:monoisotopicmass "34.96885" ; chebi:smiles "*Cl" ; oboInOwl:hasDbXref "MetaCyc:Chlorides", "Wikipedia:Organochloride" ; oboInOwl:hasExactSynonym "organochlorine compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an organochlorine molecule", "chloroorganic compounds", "chlororganische Verbindungen", "organochloride", "organochloride compound", "organochloride compounds", "organochlorides", "organochlorine compounds" ; oboInOwl:id "CHEBI:36683" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organochlorine compound" ; rdfs:subClassOf obo:CHEBI_17792, obo:CHEBI_23117 . obo:CHEBI_36688 oboInOwl:hasExactSynonym "heterotricyclic compound", "heterotricyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterotricyclic compounds" ; oboInOwl:id "CHEBI:36688" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heterotricyclic compound" ; rdfs:subClassOf obo:CHEBI_33671 . obo:CHEBI_36709 obo:IAO_0000115 "Any member of the class of quinolines in which the quinoline skeleton is substituted by one or more amino or substituted-amino groups." ; oboInOwl:hasExactSynonym "aminoquinoline" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aminoquinolines" ; oboInOwl:id "CHEBI:36709" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aminoquinoline" ; rdfs:subClassOf obo:CHEBI_26513, obo:CHEBI_33860 . obo:CHEBI_36735 obo:IAO_0000115 "Compounds based on a biladiene skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36735" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "biladienes" ; rdfs:subClassOf obo:CHEBI_25046 . obo:CHEBI_36810 obo:IAO_0000115 "A fluorohydrocarbon that is fluoroform in which the hydrogen is substituted by a phenyl group." ; chebi:charge "0" ; chebi:formula "C7H5F3" ; chebi:inchi "InChI=1S/C7H5F3/c8-7(9,10)6-4-2-1-3-5-6/h1-5H" ; chebi:inchikey "GETTZEONDQJALK-UHFFFAOYSA-N" ; chebi:mass "146.10980" ; chebi:monoisotopicmass "146.03433" ; chebi:smiles "FC(F)(F)c1ccccc1" ; oboInOwl:hasDbXref "Beilstein:1906908", "CAS:98-08-8", "Gmelin:3670", "PMID:11671431", "PMID:20958547", "PMID:24267073", "PMID:24669762", "Reaxys:1906908" ; oboInOwl:hasExactSynonym "(trifluoromethyl)benzene" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C6H5CF3", "CF3Ph", "PhCF3", "alpha,alpha,alpha-trifluorotoluene", "benzotrifluoride", "omega-trifluorotoluene", "phenylfluoroform", "trifluoromethylbenzene" ; oboInOwl:id "CHEBI:36810" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(trifluoromethyl)benzene" ; rdfs:subClassOf obo:CHEBI_46695, obo:CHEBI_83565, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_41550 ] . obo:CHEBI_36820 obo:IAO_0000115 "Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved." ; oboInOwl:hasExactSynonym "ring assemblies", "ring assembly" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36820" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ring assembly" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_36828 oboInOwl:hasExactSynonym "pseudohalide ions" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pseudohalide anions", "pseudohalides", "pseudohalogen anion", "pseudohalogen ion" ; oboInOwl:id "CHEBI:36828" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pseudohalide anion" ; rdfs:subClassOf obo:CHEBI_36829 . obo:CHEBI_36829 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic monoanions" ; oboInOwl:id "CHEBI:36829" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polyatomic monoanion" ; rdfs:subClassOf obo:CHEBI_33273, obo:CHEBI_36830 . obo:CHEBI_36830 chebi:charge "-1" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoanions" ; oboInOwl:id "CHEBI:36830" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoanion" ; rdfs:subClassOf obo:CHEBI_22563 . obo:CHEBI_36841 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "11-hydroxy steroids" ; oboInOwl:id "CHEBI:36841" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "11-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:CHEBI_36848 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-hydroxy steroids" ; oboInOwl:id "CHEBI:36848" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "5-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:CHEBI_36860 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "14-hydroxy steroids" ; oboInOwl:id "CHEBI:36860" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "14-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:CHEBI_36862 obo:IAO_0000115 "A 14-hydroxy steroid in which the hydroxy group has a beta-configuration." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "14beta-hydroxy steroids" ; oboInOwl:id "CHEBI:36862" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "14beta-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_36860 . obo:CHEBI_36892 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36892" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental fluorine" ; rdfs:subClassOf obo:CHEBI_33434 . obo:CHEBI_36893 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36893" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental iodine" ; rdfs:subClassOf obo:CHEBI_33434 . obo:CHEBI_36894 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36894" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental bromine" ; rdfs:subClassOf obo:CHEBI_33434 . obo:CHEBI_36895 chebi:charge "0" ; chebi:formula "F" ; chebi:mass "18.998" ; chebi:monoisotopicmass "18.99840" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic fluorine" ; oboInOwl:id "CHEBI:36895" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic fluorine" ; rdfs:subClassOf obo:CHEBI_36892 . obo:CHEBI_36896 chebi:charge "0" ; chebi:formula "Br" ; chebi:mass "79.904" ; chebi:monoisotopicmass "78.91834" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic bromine" ; oboInOwl:id "CHEBI:36896" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic bromine" ; rdfs:subClassOf obo:CHEBI_36894 . obo:CHEBI_36897 chebi:charge "0" ; chebi:formula "I" ; chebi:mass "126.904" ; chebi:monoisotopicmass "126.90447" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic iodine" ; oboInOwl:id "CHEBI:36897" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoatomic iodine" ; rdfs:subClassOf obo:CHEBI_36893 . obo:CHEBI_36902 oboInOwl:hasExactSynonym "chalcogen hydride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcogen hydrides" ; oboInOwl:id "CHEBI:36902" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chalcogen hydride" ; rdfs:subClassOf obo:CHEBI_33242, obo:CHEBI_33304 . obo:CHEBI_36914 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic ions" ; oboInOwl:id "CHEBI:36914" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic ion" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_24870 . obo:CHEBI_36915 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic cations" ; oboInOwl:id "CHEBI:36915" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic cation" ; rdfs:subClassOf obo:CHEBI_36914, obo:CHEBI_36916 . obo:CHEBI_36916 obo:IAO_0000115 "A monoatomic or polyatomic species having one or more elementary charges of the proton." ; oboInOwl:hasAlternativeId "CHEBI:23058", "CHEBI:3473" ; oboInOwl:hasDbXref "KEGG:C01373" ; oboInOwl:hasExactSynonym "Cation", "cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kation", "Kationen", "cationes", "cations" ; oboInOwl:id "CHEBI:36916" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cation" ; rdfs:subClassOf obo:CHEBI_24870 . obo:CHEBI_36919 oboInOwl:hasExactSynonym "antimony molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimony compounds", "antimony molecular entities" ; oboInOwl:id "CHEBI:36919" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimony molecular entity" ; rdfs:subClassOf obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_30513 ] . obo:CHEBI_36920 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimony oxoacids", "oxoacids of antimony" ; oboInOwl:id "CHEBI:36920" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimony oxoacid" ; rdfs:subClassOf obo:CHEBI_33408, obo:CHEBI_50007 . obo:CHEBI_36921 oboInOwl:hasExactSynonym "antimony oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimony oxoanions", "oxoanions of antimony" ; oboInOwl:id "CHEBI:36921" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimony oxoanion" ; rdfs:subClassOf obo:CHEBI_24834, obo:CHEBI_33459, obo:CHEBI_50007 . obo:CHEBI_36961 oboInOwl:hasExactSynonym "chalcocarbonic acid", "chalcocarbonic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcocarbonic acids" ; oboInOwl:id "CHEBI:36961" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chalcocarbonic acid" ; rdfs:subClassOf obo:CHEBI_36962 . obo:CHEBI_36962 obo:IAO_0000115 "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." ; oboInOwl:hasExactSynonym "organochalcogen compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organochalcogen compounds" ; oboInOwl:id "CHEBI:36962" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organochalcogen compound" ; rdfs:subClassOf obo:CHEBI_33285, obo:CHEBI_33304 . obo:CHEBI_36963 obo:IAO_0000115 "An organochalcogen compound containing at least one carbon-oxygen bond." ; oboInOwl:hasDbXref "PMID:17586126" ; oboInOwl:hasExactSynonym "organooxygen compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organooxygen compounds" ; oboInOwl:id "CHEBI:36963" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organooxygen compound" ; rdfs:subClassOf obo:CHEBI_25806, obo:CHEBI_36962 . obo:CHEBI_36976 obo:IAO_0000115 "A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid." ; oboInOwl:hasAlternativeId "CHEBI:13215", "CHEBI:13663", "CHEBI:7656" ; oboInOwl:hasDbXref "KEGG:C00215", "Wikipedia:Nucleotide" ; oboInOwl:hasExactSynonym "Nucleotide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleotides" ; oboInOwl:id "CHEBI:36976" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleotide" ; rdfs:subClassOf obo:CHEBI_25608 . obo:CHEBI_36982 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic purine nucleotides" ; oboInOwl:id "CHEBI:36982" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic purine nucleotide" ; rdfs:subClassOf obo:CHEBI_23447, obo:CHEBI_26395 . obo:CHEBI_37015 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleoside 5'-phosphates" ; oboInOwl:id "CHEBI:37015" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribonucleoside 5'-phosphate" ; rdfs:subClassOf obo:CHEBI_16701, obo:CHEBI_26561 . obo:CHEBI_37022 oboInOwl:hasExactSynonym "amino-acid anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino acid anions", "amino-acid anions" ; oboInOwl:id "CHEBI:37022" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amino-acid anion" ; rdfs:subClassOf obo:CHEBI_29067, obo:CHEBI_35352, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33709 ] . obo:CHEBI_37045 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine ribonucleoside 5'-triphosphates" ; oboInOwl:id "CHEBI:37045" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "purine ribonucleoside 5'-triphosphate" ; rdfs:subClassOf obo:CHEBI_26398, obo:CHEBI_26400, obo:CHEBI_37076 . obo:CHEBI_37076 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleoside 5'-triphosphates" ; oboInOwl:id "CHEBI:37076" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribonucleoside 5'-triphosphate" ; rdfs:subClassOf obo:CHEBI_37015 . obo:CHEBI_37096 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenosine 5'-phosphates" ; oboInOwl:id "CHEBI:37096" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adenosine 5'-phosphate" ; rdfs:subClassOf obo:CHEBI_22256 . obo:CHEBI_37141 obo:IAO_0000115 "A compound containing at least one carbon-bromine bond." ; chebi:charge "0" ; chebi:formula "BrR" ; chebi:mass "79.904" ; chebi:monoisotopicmass "78.91834" ; chebi:smiles "*Br" ; oboInOwl:hasDbXref "MetaCyc:Bromide", "Wikipedia:Organobromine_compound" ; oboInOwl:hasExactSynonym "organobromine compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an organobromine molecule", "bromoorganic compound", "organobromide", "organobromide compound", "organobromide compounds", "organobromides", "organobromine compounds" ; oboInOwl:id "CHEBI:37141" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organobromine compound" ; rdfs:subClassOf obo:CHEBI_17792, obo:CHEBI_22928 . obo:CHEBI_37143 obo:IAO_0000115 "An organofluorine compound is a compound containing at least one carbon-fluorine bond." ; chebi:charge "0" ; chebi:formula "FR" ; chebi:mass "18.998" ; chebi:monoisotopicmass "18.99840" ; chebi:smiles "*F" ; oboInOwl:hasDbXref "MetaCyc:Fluorides" ; oboInOwl:hasExactSynonym "organofluorine compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fluoroorganic compound", "fluoroorganic compounds", "fluoroorganics", "fluororganische Verbindungen", "organofluorine compounds" ; oboInOwl:id "CHEBI:37143" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organofluorine compound" ; rdfs:subClassOf obo:CHEBI_17792, obo:CHEBI_24062 . obo:CHEBI_37163 obo:IAO_0000115 "A polysaccharide composed of glucose residues." ; chebi:formula "C12H22O11(C6H10O5)n" ; oboInOwl:hasAlternativeId "CHEBI:24255", "CHEBI:5392" ; oboInOwl:hasDbXref "CAS:9037-91-6", "KEGG:C01379" ; oboInOwl:hasExactSynonym "Glucan", "glucan" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glucans" ; oboInOwl:id "CHEBI:37163" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glucan" ; rdfs:subClassOf obo:CHEBI_37164 . obo:CHEBI_37164 obo:IAO_0000115 "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." ; oboInOwl:hasExactSynonym "homopolysaccharide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "homoglycan", "homopolysaccharides" ; oboInOwl:id "CHEBI:37164" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "homopolysaccharide" ; rdfs:subClassOf obo:CHEBI_18154 . obo:CHEBI_37175 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic hydrides" ; oboInOwl:id "CHEBI:37175" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic hydride" ; rdfs:subClassOf obo:CHEBI_33692 . obo:CHEBI_37176 oboInOwl:hasExactSynonym "mononuclear parent hydrides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mononuclear hydride", "mononuclear hydrides" ; oboInOwl:id "CHEBI:37176" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mononuclear parent hydride" ; rdfs:subClassOf obo:CHEBI_33692 . obo:CHEBI_37206 obo:IAO_0000115 "A polyol that contains 6 hydroxy groups." ; oboInOwl:hasExactSynonym "hexol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hexols" ; oboInOwl:id "CHEBI:37206" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hexol" ; rdfs:subClassOf obo:CHEBI_26191 . obo:CHEBI_37246 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37246" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental sodium" ; rdfs:subClassOf obo:CHEBI_26712 . obo:CHEBI_37253 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37253" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental zinc" ; rdfs:subClassOf obo:CHEBI_27364 . obo:CHEBI_37395 obo:IAO_0000115 "Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid." ; oboInOwl:hasAlternativeId "CHEBI:25425", "CHEBI:7011" ; oboInOwl:hasDbXref "KEGG:C05114" ; oboInOwl:hasExactSynonym "Mucopolysaccharide", "mucopolysaccharides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Mucopolysaccharid", "Mukopolysaccharid", "mucopolisacarido", "mucopolisacaridos" ; oboInOwl:id "CHEBI:37395" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mucopolysaccharide" ; rdfs:subClassOf obo:CHEBI_18085 . obo:CHEBI_37404 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37404" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "elemental copper" ; rdfs:subClassOf obo:CHEBI_23377 . obo:CHEBI_37415 obo:IAO_0000115 "A heterodetic cyclic peptide consisting of eight amino acid residues and containing a thioether bridge between a cysteine and a tryptophan residue. It is found in a number of poisonous mushrooms, including Amanita phalloides (the death cap), Galerina marginata, and and Conocybe filaris." ; chebi:charge "0" ; chebi:formula "C39H54N10O14S" ; chebi:inchi "InChI=1S/C39H54N10O14S/c1-4-16(2)31-36(60)42-11-29(55)43-25-15-64(63)38-21(20-6-5-18(51)7-22(20)46-38)9-23(33(57)41-12-30(56)47-31)44-37(61)32(17(3)27(53)14-50)48-35(59)26-8-19(52)13-49(26)39(62)24(10-28(40)54)45-34(25)58/h5-7,16-17,19,23-27,31-32,46,50-53H,4,8-15H2,1-3H3,(H2,40,54)(H,41,57)(H,42,60)(H,43,55)(H,44,61)(H,45,58)(H,47,56)(H,48,59)/t16-,17-,19+,23-,24-,25-,26-,27-,31-,32-,64+/m0/s1" ; chebi:inchikey "CIORWBWIBBPXCG-SXZCQOKQSA-N" ; chebi:mass "918.97106" ; chebi:monoisotopicmass "918.35417" ; chebi:smiles "[H][C@]12Cc3c([nH]c4cc(O)ccc34)[S@](=O)C[C@]([H])(NC(=O)CNC(=O)[C@@]([H])(NC(=O)CNC1=O)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1C[C@H](O)C[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)[C@@H](O)CO)C(=O)N2" ; oboInOwl:hasAlternativeId "CHEBI:10207", "CHEBI:37414" ; oboInOwl:hasDbXref "Beilstein:1071138", "CAS:23109-05-9", "KEGG:C08438", "KNApSAcK:C00001516", "PMID:109306", "PMID:17525082", "PMID:19556115", "PMID:20529816", "PMID:23763309", "PMID:6208374", "PMID:6630208", "PMID:9093889", "Reaxys:1071138", "Wikipedia:Alpha-amanitin" ; oboInOwl:hasExactSynonym "1,8-anhydro-S(1),C(2.5)-cyclo[L-cysteinyl-L-asparaginyl-trans-4-hydroxy-L-prolyl-(R)-4,5-dihydroxy-L-isoleucyl-6-hydroxy-L-tryptophylglycyl-L-isoleucylglycine] (R)-S(1)-oxide", "alpha-Amanitin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-Amanitine", "alpha-Amatoxin" ; oboInOwl:id "CHEBI:37415" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-amanitin" ; rdfs:subClassOf obo:CHEBI_24533, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25442 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37416 ] . obo:CHEBI_37416 obo:IAO_0000115 "An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6)." ; oboInOwl:hasDbXref "Wikipedia:RNA_polymerase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C RNA formation factors inhibitor", "C RNA formation factors inhibitors", "C ribonucleic acid formation factors inhibitor", "C ribonucleic acid formation factors inhibitors", "DNA-dependent RNA nucleotidyltransferase inhibitor", "DNA-dependent RNA nucleotidyltransferase inhibitors", "DNA-dependent RNA polymerase inhibitor", "DNA-dependent RNA polymerase inhibitors", "DNA-dependent ribonucleate nucleotidyltransferase inhibitor", "DNA-dependent ribonucleate nucleotidyltransferase inhibitors", "DNA-directed RNA polymerase inhibitor", "DNA-directed RNA polymerase inhibitors", "DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitor", "DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitors", "EC 2.7.7.6 (RNA polymerase) inhibitors", "EC 2.7.7.6 inhibitor", "EC 2.7.7.6 inhibitors", "RNA nucleotidyltransferase (DNA-directed) inhibitor", "RNA nucleotidyltransferase (DNA-directed) inhibitors", "RNA nucleotidyltransferase inhibitor", "RNA nucleotidyltransferase inhibitors", "RNA polymerase (EC 2.7.7.6) inhibitor", "RNA polymerase (EC 2.7.7.6) inhibitors", "RNA polymerase I inhibitor", "RNA polymerase I inhibitors", "RNA polymerase II inhibitor", "RNA polymerase II inhibitors", "RNA polymerase III inhibitor", "RNA polymerase III inhibitors", "RNA polymerase inhibitor", "RNA polymerase inhibitors", "RNA transcriptase inhibitor", "RNA transcriptase inhibitors", "deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitor", "deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitors", "directed RNA polymerase inhibitor", "nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitor", "nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitors", "ribonucleate nucleotidyltransferase inhibitor", "ribonucleate nucleotidyltransferase inhibitors", "ribonucleate polymerase inhibitor", "ribonucleate polymerase inhibitors", "ribonucleic acid nucleotidyltransferase inhibitor", "ribonucleic acid nucleotidyltransferase inhibitors", "ribonucleic acid polymerase inhibitor", "ribonucleic acid polymerase inhibitors", "ribonucleic acid transcriptase inhibitor", "ribonucleic acid transcriptase inhibitors", "ribonucleic polymerase inhibitor", "ribonucleic polymerase inhibitors", "ribonucleic transcriptase inhibitor", "ribonucleic transcriptase inhibitors", "transcriptase inhibitor", "transcriptase inhibitors" ; oboInOwl:id "CHEBI:37416" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.7.7.6 (RNA polymerase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76815 . obo:CHEBI_37526 chebi:charge "0" ; chebi:formula "C20H34" ; chebi:inchi "InChI=1S/C20H34/c1-11-6-14-7-12(2)9-16-18(15(14)8-11)13(3)10-17-19(16)20(17,4)5/h11-19H,6-10H2,1-5H3/t11-,12+,13-,14+,15-,16-,17-,18-,19+/m1/s1" ; chebi:inchikey "CGVXVPQJMYMMIH-HKDZDBKOSA-N" ; chebi:mass "274.485" ; chebi:monoisotopicmass "274.26605" ; chebi:smiles "C1[C@@]2([C@@]([C@]3([C@@](C[C@H](C3)C)(C[C@@H]1C)[H])[H])([C@H](C)C[C@@]4([C@]2(C4(C)C)[H])[H])[H])[H]" ; oboInOwl:hasDbXref "CAS:67707-87-3" ; oboInOwl:hasExactSynonym "(1aS,1bR,3S,4aS,6R,7aR,7bR,8R,9aR)-1,1,3,6,8-pentamethyltetradecahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulene", "tigliane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Tiglian" ; oboInOwl:id "CHEBI:37526" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tigliane" ; rdfs:subClassOf obo:CHEBI_35190, obo:CHEBI_35662 . obo:CHEBI_37527 obo:IAO_0000115 "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." ; oboInOwl:hasAlternativeId "CHEBI:13800", "CHEBI:13801", "CHEBI:22209", "CHEBI:2426" ; oboInOwl:hasDbXref "KEGG:C00174" ; oboInOwl:hasExactSynonym "Acid", "acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Saeure", "Saeuren", "acide", "acido", "acids" ; oboInOwl:id "CHEBI:37527" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acid" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_37532 obo:IAO_0000115 "Esters of phorbol, originally found in croton oil (from Croton tiglium, of the family Euphorbiaceae). A number of phorbol esters possess activity as tumour promoters and activate the mechanisms associated with cell growth. Some of these are used in experiments as activators of protein kinase C." ; oboInOwl:hasDbXref "PMID:17661218", "PMID:19944127", "PMID:27007372" ; oboInOwl:hasExactSynonym "phorbol ester" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37532" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phorbol ester" ; rdfs:subClassOf obo:CHEBI_33308, obo:CHEBI_52557, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_8116 ] . obo:CHEBI_37577 obo:IAO_0000115 "A molecular entity consisting of two or more chemical elements." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chemical compound", "heteroatomic molecular entities" ; oboInOwl:id "CHEBI:37577" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heteroatomic molecular entity" ; rdfs:subClassOf obo:CHEBI_36357 . obo:CHEBI_37578 obo:IAO_0000115 "Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements." ; oboInOwl:hasDbXref "Wikipedia:Halide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halides" ; oboInOwl:id "CHEBI:37578" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halide" ; rdfs:subClassOf obo:CHEBI_24471, obo:CHEBI_37577 . obo:CHEBI_37581 obo:IAO_0000115 "A lactone having a five-membered lactone ring." ; chebi:charge "0" ; chebi:formula "C4H3O2R3" ; chebi:mass "83.066" ; chebi:monoisotopicmass "83.01330" ; chebi:smiles "O1C(C(C(C1=O)*)*)*" ; oboInOwl:hasAlternativeId "CHEBI:13194", "CHEBI:18937", "CHEBI:22971", "CHEBI:541" ; oboInOwl:hasDbXref "PMID:18789684" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,4-Lactone", "1,4-lactones", "a 1,4-lactone", "butyrolactones", "gamma-Laktone", "gamma-lactona", "gamma-lactonas", "gamma-lactones" ; oboInOwl:id "CHEBI:37581" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "gamma-lactone" ; rdfs:subClassOf obo:CHEBI_25000 . obo:CHEBI_37622 obo:IAO_0000115 "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." ; chebi:charge "0" ; chebi:formula "CNOR3" ; chebi:mass "42.01680" ; chebi:monoisotopicmass "41.99799" ; chebi:smiles "[*]C(=O)N([*])[*]" ; oboInOwl:hasAlternativeId "CHEBI:35354", "CHEBI:35355" ; oboInOwl:hasExactSynonym "carboxamides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carboxamides", "primary carboxamide" ; oboInOwl:id "CHEBI:37622" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carboxamide" ; rdfs:subClassOf obo:CHEBI_33256, obo:CHEBI_35352, obo:CHEBI_36963, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_23004 ] . obo:CHEBI_37699 obo:IAO_0000115 "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "protein kinase inhibitors" ; oboInOwl:id "CHEBI:37699" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "protein kinase inhibitor" ; rdfs:subClassOf obo:CHEBI_76668 . obo:CHEBI_37733 obo:IAO_0000115 "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "BChE inhibitor", "BChE inhibitors", "BtChoEase inhibitor", "BtChoEase inhibitors", "EC 3.1.1.8 (cholinesterase) inhibitors", "EC 3.1.1.8 inhibitor", "EC 3.1.1.8 inhibitors", "anticholineesterase inhibitor", "anticholineesterase inhibitors", "anticholinesterase", "anticholinesterases", "benzoylcholinesterase inhibitor", "benzoylcholinesterase inhibitors", "butyrylcholine esterase inhibitor", "butyrylcholine esterase inhibitors", "butyrylcholinesterase inhibitor", "butyrylcholinesterase inhibitors", "choline esterase II (unspecific) inhibitor", "choline esterase II (unspecific) inhibitors", "choline esterase inhibitor", "choline esterase inhibitors", "cholinesterase (EC 3.1.1.8) inhibitor", "cholinesterase (EC 3.1.1.8) inhibitors", "cholinesterase inhibitor", "non-specific cholinesterase inhibitor", "non-specific cholinesterase inhibitors", "propionylcholinesterase inhibitor", "propionylcholinesterase inhibitors", "pseudocholinesterase inhibitor", "pseudocholinesterase inhibitors" ; oboInOwl:id "CHEBI:37733" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.1.1.8 (cholinesterase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76773 . obo:CHEBI_37734 oboInOwl:hasAlternativeId "CHEBI:26019" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37734" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "phosphoric ester" ; rdfs:subClassOf obo:CHEBI_26079, obo:CHEBI_35701 . obo:CHEBI_37739 obo:IAO_0000115 "Any glycerolipid having a phosphate group ester-linked to a terminal carbon of the glycerol backbone." ; oboInOwl:hasAlternativeId "CHEBI:24362", "CHEBI:5456" ; oboInOwl:hasDbXref "PMID:17393491" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glycerophospholipids", "phosphatide", "phosphatides", "phosphoglyceride", "phosphoglycerides" ; oboInOwl:id "CHEBI:37739" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycerophospholipid" ; rdfs:subClassOf obo:CHEBI_16247, obo:CHEBI_35741 . obo:CHEBI_37749 oboInOwl:hasExactSynonym "halogen oxide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogen oxides" ; oboInOwl:id "CHEBI:37749" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halogen oxide" ; rdfs:subClassOf obo:CHEBI_24471, obo:CHEBI_24836 . obo:CHEBI_37750 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chlorine oxides" ; oboInOwl:id "CHEBI:37750" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chlorine oxide" ; rdfs:subClassOf obo:CHEBI_37749 . obo:CHEBI_37826 oboInOwl:hasExactSynonym "sulfuric acid derivative" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfuric acid derivatives" ; oboInOwl:id "CHEBI:37826" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfuric acid derivative" ; rdfs:subClassOf obo:CHEBI_33424, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_26836 ] . obo:CHEBI_37838 obo:IAO_0000115 "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." ; oboInOwl:hasExactSynonym "carboacyl groups", "carboxylic acyl group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carboxylic acyl groups" ; oboInOwl:id "CHEBI:37838" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carboacyl group" ; rdfs:subClassOf obo:CHEBI_22221, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_33575 ] . obo:CHEBI_37868 obo:IAO_0000115 "A fatty alcohol consisting of a hydroxy function at any position of an unbranched saturated chain of eight carbon atoms." ; chebi:charge "0" ; chebi:formula "C8H18O" ; chebi:mass "130.228" ; chebi:monoisotopicmass "130.13577" ; oboInOwl:hasDbXref "CAS:29063-28-3" ; oboInOwl:hasExactSynonym "octanol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Oktanol", "Oktylalkohol", "n-octanol", "octyl alcohol" ; oboInOwl:id "CHEBI:37868" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "octanol" ; rdfs:subClassOf obo:CHEBI_134179, obo:CHEBI_24026, obo:CHEBI_2571, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_17590 ] . obo:CHEBI_37886 obo:IAO_0000115 "An agent that selectively binds to and activates adrenergic receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adrenergic agonists", "adrenergic receptor agonist", "adrenoceptor agonists", "adrenomimetic", "adrenomimetics" ; oboInOwl:id "CHEBI:37886" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adrenergic agonist" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_37887 obo:IAO_0000115 "An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adrenergic antagonists", "adrenergic blockaders", "adrenergic blocker", "adrenergic blockers", "adrenergic receptor blockaders", "adrenoceptor antagonists" ; oboInOwl:id "CHEBI:37887" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adrenergic antagonist" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_37890 obo:IAO_0000115 "An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-adrenergic antagonists", "alpha-adrenergic blocker", "alpha-adrenergic blockers", "alpha-adrenergic receptor blockaders", "alpha-adrenoceptor antagonists" ; oboInOwl:id "CHEBI:37890" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-adrenergic antagonist" ; rdfs:subClassOf obo:CHEBI_37887, obo:CHEBI_48539 . obo:CHEBI_37948 obo:IAO_0000115 "A spiro compound in which at least one of the cyclic components is an oxygen heterocyle." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxaspiro compounds" ; oboInOwl:id "CHEBI:37948" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxaspiro compound" ; rdfs:subClassOf obo:CHEBI_33599 . obo:CHEBI_37955 obo:IAO_0000115 "H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine." ; oboInOwl:hasDbXref "PMID:22035879" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H1 antihistaminics", "H1 receptor antagonists", "H1 receptor blockaders", "H1-receptor antagonists", "H1-receptor blocker", "H1-receptor blockers", "classical antihistamines", "classical antihistaminics" ; oboInOwl:id "CHEBI:37955" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "H1-receptor antagonist" ; rdfs:subClassOf obo:CHEBI_37956 . obo:CHEBI_37956 obo:IAO_0000115 "Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists." ; oboInOwl:hasDbXref "PMID:22035879", "Wikipedia:Antihistamines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antihistamine", "antihistamines", "antihistaminico", "antihistaminics", "histamine receptor blocker", "histamine receptor blockers" ; oboInOwl:id "CHEBI:37956" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "histamine antagonist" ; rdfs:subClassOf obo:CHEBI_37957, obo:CHEBI_48706 . obo:CHEBI_37957 obo:IAO_0000115 "Drugs used for their actions on histaminergic systems." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "histamine agents", "histamine drugs", "histaminergic agent", "histaminergic agents", "histaminergic drugs" ; oboInOwl:id "CHEBI:37957" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "histaminergic drug" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_37962 obo:IAO_0000115 "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adrenergic agents", "adrenergic drug", "adrenergic drugs", "adrenergic neuron agents", "adrenergics" ; oboInOwl:id "CHEBI:37962" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adrenergic agent" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_38032 obo:IAO_0000115 "A carbopolyclic compound comprising of three carbocyclic rings." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbotricyclic compounds" ; oboInOwl:id "CHEBI:38032" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbotricyclic compound" ; rdfs:subClassOf obo:CHEBI_35294, obo:CHEBI_51959 . obo:CHEBI_38068 obo:IAO_0000115 "A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimalarials" ; oboInOwl:id "CHEBI:38068" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimalarial" ; rdfs:subClassOf obo:CHEBI_64915 . obo:CHEBI_38070 obo:IAO_0000115 "A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-arrhythmia agent", "antiarrhythmic agent" ; oboInOwl:id "CHEBI:38070" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anti-arrhythmia drug" ; rdfs:subClassOf obo:CHEBI_35554 . obo:CHEBI_38077 obo:IAO_0000115 "A compound composed of two or more pyrrole units." ; oboInOwl:hasDbXref "Beilstein:8538310" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "PPys", "poly(pyrrole)s", "polypyrroles" ; oboInOwl:id "CHEBI:38077" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polypyrrole" ; rdfs:subClassOf obo:CHEBI_38101 . obo:CHEBI_38092 obo:IAO_0000115 "Any member of the class of cardenolides with glycosyl residues attached to position 3." ; oboInOwl:hasAlternativeId "CHEBI:23035", "CHEBI:38080", "CHEBI:38082" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5alpha-cardenolide glycoside", "5beta-cardenolide glycoside" ; oboInOwl:id "CHEBI:38092" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cardenolide glycoside" ; rdfs:subClassOf obo:CHEBI_74634, obo:CHEBI_83970 . obo:CHEBI_38101 obo:IAO_0000115 "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterocyclic organonitrogen compounds", "organonitrogen heterocyclic compounds" ; oboInOwl:id "CHEBI:38101" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organonitrogen heterocyclic compound" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_35352 . obo:CHEBI_38104 obo:IAO_0000115 "Any organic heterocyclic compound containing at least one ring oxygen atom." ; oboInOwl:hasDbXref "PMID:17134300" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterocyclic organooxygen compounds", "organooxygen heterocyclic compounds", "oxacycles" ; oboInOwl:id "CHEBI:38104" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxacycle" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_36963 . obo:CHEBI_38106 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterocyclic organosulfur compounds", "organosulfur heterocyclic compounds" ; oboInOwl:id "CHEBI:38106" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organosulfur heterocyclic compound" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_33261 . obo:CHEBI_38147 obo:IAO_0000115 "A drug that has a strengthening effect on the heart or that can increase cardiac output." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cardiotonic drugs" ; oboInOwl:id "CHEBI:38147" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cardiotonic drug" ; rdfs:subClassOf obo:CHEBI_35554 . obo:CHEBI_38166 oboInOwl:hasAlternativeId "CHEBI:25429", "CHEBI:38075" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic heteropolycyclic compounds" ; oboInOwl:id "CHEBI:38166" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic heteropolycyclic compound" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_33671 . obo:CHEBI_38179 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monocyclic heteroarenes" ; oboInOwl:id "CHEBI:38179" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monocyclic heteroarene" ; rdfs:subClassOf obo:CHEBI_33833 . obo:CHEBI_38180 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polycyclic heteroarenes" ; oboInOwl:id "CHEBI:38180" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polycyclic heteroarene" ; rdfs:subClassOf obo:CHEBI_33833 . obo:CHEBI_38195 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5beta-hydroxy steroids" ; oboInOwl:id "CHEBI:38195" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "5beta-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_136889, obo:CHEBI_36848 . obo:CHEBI_38215 obo:IAO_0000115 "One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium channel antagonist", "calcium channel antagonists", "calcium channel blockers" ; oboInOwl:id "CHEBI:38215" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "calcium channel blocker" ; rdfs:subClassOf obo:CHEBI_38808, obo:CHEBI_48706 . obo:CHEBI_38222 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38222" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "hydrocarbyl anion" ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_38260 obo:IAO_0000115 "Any of a class of heterocyclic amines having a saturated five-membered ring." ; oboInOwl:hasAlternativeId "CHEBI:26922", "CHEBI:38191" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38260" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyrrolidines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_38275 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyrrolidinones" ; oboInOwl:id "CHEBI:38275" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyrrolidinone" ; rdfs:subClassOf obo:CHEBI_38260 . obo:CHEBI_38313 obo:IAO_0000115 "Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38313" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diazines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_38314 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38314" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyrazines" ; rdfs:subClassOf obo:CHEBI_38313 . obo:CHEBI_38323 obo:IAO_0000115 "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cholinergic agent", "cholinergic drugs", "cholinomimetic" ; oboInOwl:id "CHEBI:38323" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cholinergic drug" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_38324 obo:IAO_0000115 "Any drug that binds to and activates cholinergic receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acetylcholine agonist", "acetylcholine agonists", "acetylcholine receptor agonist", "cholinergic agonists", "cholinomimetic", "cholinomimetics" ; oboInOwl:id "CHEBI:38324" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cholinergic agonist" ; rdfs:subClassOf obo:CHEBI_38323 . obo:CHEBI_38325 obo:IAO_0000115 "Any drug that binds to and activates a muscarinic cholinergic receptor." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "muscarinic acetylcholine receptor agonist", "muscarinic agonists", "muscarinic cholinergic agonist", "muscarinic cholinergic agonists" ; oboInOwl:id "CHEBI:38325" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "muscarinic agonist" ; rdfs:subClassOf obo:CHEBI_38324 . obo:CHEBI_38329 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38329" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxazolidines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101, obo:CHEBI_38104 . obo:CHEBI_38337 obo:IAO_0000115 "A pyrimidine carrying one or more oxo substituents." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyrimidones" ; oboInOwl:id "CHEBI:38337" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyrimidone" ; rdfs:subClassOf obo:CHEBI_39447 . obo:CHEBI_38366 obo:IAO_0000115 "A pent-3-enoic acid in trans- configuration." ; chebi:charge "0" ; chebi:formula "C5H8O2" ; chebi:inchi "InChI=1S/C5H8O2/c1-2-3-4-5(6)7/h3-4H,2H2,1H3,(H,6,7)/b4-3+" ; chebi:inchikey "YIYBQIKDCADOSF-ONEGZZNKSA-N" ; chebi:mass "100.11582" ; chebi:monoisotopicmass "100.05243" ; chebi:smiles "CC\\C=C\\C(O)=O" ; oboInOwl:hasDbXref "CAS:13991-37-2", "LIPID_MAPS_instance:LMFA01030005", "Reaxys:1720312" ; oboInOwl:hasExactSynonym "(2E)-pent-2-enoic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2E)-2-pentenoic acid", "(E)-2-pentenic acid", "(E)-2-pentenoic acid", "(E)-pent-2-en-1-oic acid", "5:1, n-3 trans", "C5:1, n-3 trans", "E-2-Pentencarbonsaeure", "Pent-2t-ensaeure", "trans-2-pentenic acid", "trans-2-pentenoic acid", "trans-Pent-2-ensaeure", "trans-alpha,beta-penteneoic acid" ; oboInOwl:id "CHEBI:38366" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "trans-pent-2-enoic acid" ; rdfs:subClassOf obo:CHEBI_35939 . obo:CHEBI_38461 obo:IAO_0000115 "Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR(1)R(2), where ROH is an alcohol, oxime, or phenol and R(1) is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbamate insecticides" ; oboInOwl:id "CHEBI:38461" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbamate insecticide" ; rdfs:subClassOf obo:CHEBI_24852, obo:CHEBI_38462 . obo:CHEBI_38462 obo:IAO_0000115 "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid." ; oboInOwl:hasDbXref "Wikipedia:Acetylcholinesterase_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "AChEI", "AcCholE inhibitor", "AcCholE inhibitors", "EC 3.1.1.7 (acetylcholinesterase) inhibitors", "EC 3.1.1.7 inhibitor", "EC 3.1.1.7 inhibitors", "acetyl.beta-methylcholinesterase inhibitor", "acetyl.beta-methylcholinesterase inhibitors", "acetylcholine acetylhydrolase inhibitor", "acetylcholine acetylhydrolase inhibitors", "acetylcholine esterase inhibitor", "acetylcholine hydrolase inhibitor", "acetylcholine hydrolase inhibitors", "acetylcholinesterase (EC 3.1.1.7) inhibitor", "acetylcholinesterase (EC 3.1.1.7) inhibitors", "acetylcholinesterase inhibitor", "acetylcholinesterase inhibitors", "acetylthiocholinesterase inhibitor", "acetylthiocholinesterase inhibitors", "choline esterase I inhibitor", "choline esterase I inhibitors", "cholinesterase inhibitor", "cholinesterase inhibitors", "true cholinesterase inhibitor", "true cholinesterase inhibitors" ; oboInOwl:id "CHEBI:38462" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.1.1.7 (acetylcholinesterase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76773 . obo:CHEBI_38515 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isoquinoline alkaloid fundamental parents" ; oboInOwl:id "CHEBI:38515" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isoquinoline alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35506 . obo:CHEBI_38534 chebi:charge "0" ; chebi:formula "C3H7NOS" ; chebi:inchi "InChI=1S/C3H7NOS/c1-3(4-5)6-2/h5H,1-2H3" ; chebi:inchikey "TYEVWCPZVQACAE-UHFFFAOYSA-N" ; chebi:mass "105.15982" ; chebi:monoisotopicmass "105.02484" ; chebi:smiles "CSC(C)=NO" ; oboInOwl:hasDbXref "Beilstein:1901214", "CAS:13749-94-5" ; oboInOwl:hasExactSynonym "methyl N-hydroxyethanimidothioate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-(Methylthio)acetaldehyde oxime", "1-(Methylthio)acetaldoxime", "Methomyl oxime", "Methyl N-hydroxyacetimidothioate", "Methyl N-hydroxyethanimidothioate", "Methyl thioacetohydroxamate" ; oboInOwl:id "CHEBI:38534" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "1-(methylsulfanyl)acetaldoxime" ; rdfs:subClassOf obo:CHEBI_86315, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_51280 ] . obo:CHEBI_38627 obo:IAO_0000115 "The parent structure of the diazines." ; chebi:charge "0" ; chebi:formula "C4H4N2" ; chebi:mass "80.088" ; chebi:monoisotopicmass "80.03745" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Diazin" ; oboInOwl:id "CHEBI:38627" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diazine" ; rdfs:subClassOf obo:CHEBI_35555, obo:CHEBI_38179, obo:CHEBI_38313, obo:CHEBI_50893 . obo:CHEBI_38631 oboInOwl:hasAlternativeId "CHEBI:22503", "CHEBI:24792" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aminoalkylindoles" ; oboInOwl:id "CHEBI:38631" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aminoalkylindole" ; rdfs:subClassOf obo:CHEBI_24828 . obo:CHEBI_38632 obo:IAO_0000115 "Any agent that affects the transport of molecular entities across a biological membrane." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "membrane transport modulators" ; oboInOwl:id "CHEBI:38632" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "membrane transport modulator" ; rdfs:subClassOf obo:CHEBI_52208 . obo:CHEBI_38700 oboInOwl:hasExactSynonym "organic sodium salt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic sodium salts" ; oboInOwl:id "CHEBI:38700" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic sodium salt" ; rdfs:subClassOf obo:CHEBI_24868, obo:CHEBI_26714 . obo:CHEBI_38702 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic sodium salts" ; oboInOwl:id "CHEBI:38702" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic sodium salt" ; rdfs:subClassOf obo:CHEBI_24839, obo:CHEBI_26714 . obo:CHEBI_38716 obo:IAO_0000115 "Any dianion containing at least one carboxy group." ; oboInOwl:hasExactSynonym "carboxylic acid dianion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carboxylic acid dianions" ; oboInOwl:id "CHEBI:38716" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carboxylic acid dianion" ; rdfs:subClassOf obo:CHEBI_29067 . obo:CHEBI_38808 obo:IAO_0000115 "A membrane transport modulator that is able to regulate intracellular calcium levels." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium channel modulators" ; oboInOwl:id "CHEBI:38808" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "calcium channel modulator" ; rdfs:subClassOf obo:CHEBI_38632 . obo:CHEBI_38809 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RyR modulator", "ryanodine receptor modulators", "ryanodine-sensitive calcium channel modulator", "ryanodine-sensitive calcium-release channel modulator" ; oboInOwl:id "CHEBI:38809" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ryanodine receptor modulator" ; rdfs:subClassOf obo:CHEBI_38808 . obo:CHEBI_38824 obo:IAO_0000115 "Compounds consisting wholly of fluorine and carbon." ; oboInOwl:hasExactSynonym "fluorocarbon", "fluorocarbons" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fluorocarbons" ; oboInOwl:id "CHEBI:38824" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluorocarbon" ; rdfs:subClassOf obo:CHEBI_37143 . obo:CHEBI_38825 chebi:charge "0" ; chebi:formula "CF4" ; chebi:inchi "InChI=1S/CF4/c2-1(3,4)5" ; chebi:inchikey "TXEYQDLBPFQVAA-UHFFFAOYSA-N" ; chebi:mass "88.00431" ; chebi:monoisotopicmass "87.99361" ; chebi:smiles "FC(F)(F)F" ; oboInOwl:hasDbXref "Beilstein:1697288", "CAS:75-73-0", "Gmelin:2016" ; oboInOwl:hasExactSynonym "tetrafluoromethane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CF4", "Freon 14", "Halon 14", "Tetrafluorkohlenstoff", "Tetrafluormethan", "carbon tetrafluoride", "perfluoromethane", "tetrafluoridocarbon", "tetrafluorocarbon" ; oboInOwl:id "CHEBI:38825" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tetrafluoromethane" ; rdfs:subClassOf obo:CHEBI_38824, obo:CHEBI_39281, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_38867 obo:IAO_0000115 "Substance which produces loss of feeling or sensation." ; oboInOwl:hasExactSynonym "anaesthetic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Anaesthetika", "Anaesthetikum", "anaesthetics", "anesthetic agent", "anesthetic drug", "anesthetics" ; oboInOwl:id "CHEBI:38867" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anaesthetic" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_38869 obo:IAO_0000115 "Substance that produces loss of consciousness." ; oboInOwl:hasExactSynonym "general anaesthetic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Allgemeinanaesthetika", "Allgemeinanaesthetikum", "general anaesthetics", "general anesthetics" ; oboInOwl:id "CHEBI:38869" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "general anaesthetic" ; rdfs:subClassOf obo:CHEBI_38867 . obo:CHEBI_38870 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Inhalationsanaesthetika", "Inhalationsanaesthetikum", "Inhalationsnarkotika", "Inhalationsnarkotikum", "anesthetic gases", "inhalation anesthetics" ; oboInOwl:id "CHEBI:38870" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inhalation anaesthetic" ; rdfs:subClassOf obo:CHEBI_38869 . obo:CHEBI_38924 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dibenzothiepines" ; oboInOwl:id "CHEBI:38924" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dibenzothiepine" ; rdfs:subClassOf obo:CHEBI_26979, obo:CHEBI_38106 . obo:CHEBI_38958 obo:IAO_0000115 "An alkaloid containing an indole skeleton." ; oboInOwl:hasAlternativeId "CHEBI:24795", "CHEBI:5901" ; oboInOwl:hasDbXref "KEGG:C06073", "Wikipedia:Indole_alkaloid" ; oboInOwl:hasExactSynonym "Indole alkaloid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "indole alkaloids" ; oboInOwl:id "CHEBI:38958" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "indole alkaloid" ; rdfs:subClassOf obo:CHEBI_22315, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_73398 ] . obo:CHEBI_39123 chebi:formula "Ca" ; chebi:mass "40.078" ; chebi:monoisotopicmass "39.96259" ; oboInOwl:hasExactSynonym "calcium cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium cations" ; oboInOwl:id "CHEBI:39123" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "calcium cation" ; rdfs:subClassOf obo:CHEBI_33513, obo:CHEBI_39124 . obo:CHEBI_39124 chebi:charge "0" ; chebi:formula "Ca" ; chebi:mass "40.078" ; chebi:monoisotopicmass "39.96259" ; oboInOwl:hasExactSynonym "calcium ion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium ions" ; oboInOwl:id "CHEBI:39124" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "calcium ion" ; rdfs:subClassOf obo:CHEBI_25213, obo:CHEBI_35155 . obo:CHEBI_39141 obo:IAO_0000115 "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." ; oboInOwl:hasExactSynonym "Bronsted acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bronsted-Saeure", "acide de Bronsted", "donneur d'hydron", "hydron donor" ; oboInOwl:id "CHEBI:39141" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "Bronsted acid" ; rdfs:subClassOf obo:CHEBI_17891, obo:CHEBI_37527 . obo:CHEBI_39142 obo:IAO_0000115 "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." ; oboInOwl:hasExactSynonym "Bronsted base" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bronsted-Base", "accepteur d'hydron", "base de Bronsted", "hydron acceptor" ; oboInOwl:id "CHEBI:39142" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "Bronsted base" ; rdfs:subClassOf obo:CHEBI_15339, obo:CHEBI_22695 . obo:CHEBI_39144 obo:IAO_0000115 "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." ; oboInOwl:hasExactSynonym "Lewis base" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Lewis-Base", "base de Lewis", "donneur d'une paire d'electrons", "electron donor" ; oboInOwl:id "CHEBI:39144" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "Lewis base" ; rdfs:subClassOf obo:CHEBI_17891, obo:CHEBI_22695 . obo:CHEBI_39162 obo:IAO_0000115 "A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has R-configuration." ; chebi:charge "0" ; chebi:formula "C10H14N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m1/s1" ; chebi:inchikey "SNICXCGAKADSCV-SNVBAGLBSA-N" ; chebi:mass "162.23160" ; chebi:monoisotopicmass "162.11570" ; chebi:smiles "CN1CCC[C@@H]1c1cccnc1" ; oboInOwl:hasDbXref "Beilstein:4666243", "Beilstein:82110", "CAS:25162-00-9", "KEGG:C16386" ; oboInOwl:hasExactSynonym "3-[(2R)-1-methylpyrrolidin-2-yl]pyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-nicotine", "(R)-3-(1-methyl-2-pyrrolidinyl)pyridine", "d-nicotine", "pseudonicotine" ; oboInOwl:id "CHEBI:39162" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(R)-nicotine" ; rdfs:subClassOf obo:CHEBI_138000, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_79008 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_17688 ] . obo:CHEBI_39208 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39208" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "antibiotic insecticide" ; rdfs:subClassOf obo:CHEBI_24852, obo:CHEBI_39215 . obo:CHEBI_39209 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39209" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "macrolide insecticide" ; rdfs:subClassOf obo:CHEBI_39221, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39208 ] . obo:CHEBI_39213 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39213" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "avermectin insecticide" ; rdfs:subClassOf obo:CHEBI_39209, obo:CHEBI_39220 . obo:CHEBI_39214 obo:IAO_0000115 "Mixture of 80% avermectin B1a and 20% avermectin B1b." ; oboInOwl:hasDbXref "CAS:71751-41-2" ; oboInOwl:hasExactSynonym "Abamectin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Agri-Mek", "Avid", "MK 936", "Zephyr", "avermectin B1" ; oboInOwl:id "CHEBI:39214" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "abamectin" ; rdfs:subClassOf obo:CHEBI_39213, obo:CHEBI_39219, obo:CHEBI_60004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29534 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29537 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39217 ] . obo:CHEBI_39215 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39215" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "antibiotic pesticide" ; rdfs:subClassOf obo:CHEBI_25944, obo:CHEBI_33281 . obo:CHEBI_39216 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39216" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "antibiotic acaricide" ; rdfs:subClassOf obo:CHEBI_22153, obo:CHEBI_39215 . obo:CHEBI_39217 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39217" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "antibiotic nematicide" ; rdfs:subClassOf obo:CHEBI_25491, obo:CHEBI_39215 . obo:CHEBI_39218 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39218" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "macrolide acaricide" ; rdfs:subClassOf obo:CHEBI_39221, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39216 ] . obo:CHEBI_39219 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39219" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "avermectin acaricide" ; rdfs:subClassOf obo:CHEBI_39218, obo:CHEBI_39220 . obo:CHEBI_39220 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39220" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "avermectin pesticide" ; rdfs:subClassOf obo:CHEBI_39221 . obo:CHEBI_39221 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39221" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "macrolide pesticide" ; rdfs:subClassOf obo:CHEBI_25105 . obo:CHEBI_39279 obo:IAO_0000115 "A haloalkane that is methane in which one (or more) of the hydrogens have been replaced by a halogen atom/halogen atoms." ; oboInOwl:hasExactSynonym "halomethane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halomethanes" ; oboInOwl:id "CHEBI:39279" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halomethane" ; rdfs:subClassOf obo:CHEBI_24469, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_16183 ] . obo:CHEBI_39281 obo:IAO_0000115 "A halomethane that is methane in which one or more hydrogens has been replaced by fluorine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39281" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluoromethanes" ; rdfs:subClassOf obo:CHEBI_24067, obo:CHEBI_39279 . obo:CHEBI_39418 obo:IAO_0000115 "Any saturated fatty acid lacking a side-chain." ; oboInOwl:hasDbXref "PMID:15644336" ; oboInOwl:hasExactSynonym "straight-chain saturated fatty acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "straight-chain saturated fatty acids" ; oboInOwl:id "CHEBI:39418" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "straight-chain saturated fatty acid" ; rdfs:subClassOf obo:CHEBI_26607, obo:CHEBI_59202, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58954 ] . obo:CHEBI_39447 obo:IAO_0000115 "Any compound having a pyrimidine as part of its structure." ; oboInOwl:hasAlternativeId "CHEBI:13681", "CHEBI:26448" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39447" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyrimidines" ; rdfs:subClassOf obo:CHEBI_38313 . obo:CHEBI_39745 obo:IAO_0000115 "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." ; chebi:charge "-1" ; chebi:formula "H2O4P" ; chebi:inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1" ; chebi:inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-M" ; chebi:mass "96.98724" ; chebi:monoisotopicmass "96.96962" ; chebi:smiles "[H]OP([O-])(=O)O[H]" ; oboInOwl:hasAlternativeId "CHEBI:29137", "CHEBI:39739" ; oboInOwl:hasDbXref "DrugBank:DB02831", "Gmelin:1999", "PDBeChem:2HP" ; oboInOwl:hasExactSynonym "dihydrogen(tetraoxidophosphate)(1-)", "dihydrogenphosphate", "dihydrogentetraoxophosphate(1-)", "dihydrogentetraoxophosphate(V)", "dihydroxidodioxidophosphate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "DIHYDROGENPHOSPHATE ION", "H2PO4(-)", "[PO2(OH)2](-)" ; oboInOwl:id "CHEBI:39745" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dihydrogenphosphate" ; rdfs:subClassOf obo:CHEBI_35780, obo:CHEBI_79389, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_43474 ] . obo:CHEBI_39832 obo:IAO_0000115 "An ether that is the methyl ether derivative of ethanol." ; chebi:charge "0" ; chebi:formula "C3H8O" ; chebi:inchi "InChI=1S/C3H8O/c1-3-4-2/h3H2,1-2H3" ; chebi:inchikey "XOBKSJJDNFUZPF-UHFFFAOYSA-N" ; chebi:mass "60.09500" ; chebi:monoisotopicmass "60.05751" ; chebi:smiles "CCOC" ; oboInOwl:hasDbXref "Beilstein:1730785", "CAS:540-67-0", "Gmelin:163978", "PDBeChem:2ME", "PMID:12662033", "Patent:KR20080019002", "Reaxys:1730785", "Wikipedia:Methoxyethane" ; oboInOwl:hasExactSynonym "METHOXYETHANE", "methoxyethane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-methoxyethane", "Aethylmethylaether", "C2H5OCH3", "Methoxyethan", "Methylaethylaether", "methyl ethyl ether" ; oboInOwl:id "CHEBI:39832" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methoxyethane" ; rdfs:subClassOf obo:CHEBI_25698, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39144 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16236 ] . obo:CHEBI_3992 oboInOwl:hasDbXref "KEGG:C02019" ; oboInOwl:hasExactSynonym "Cyclic ketone", "cyclic ketones" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:3992" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic ketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_4046 obo:IAO_0000115 "The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia." ; chebi:charge "0" ; chebi:formula "C21H21N" ; chebi:inchi "InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3" ; chebi:inchikey "JJCFRYNCJDLXIK-UHFFFAOYSA-N" ; chebi:mass "287.39810" ; chebi:monoisotopicmass "287.16740" ; chebi:smiles "CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12" ; oboInOwl:hasAlternativeId "CHEBI:111005", "CHEBI:605605" ; oboInOwl:hasDbXref "Beilstein:1348386", "CAS:129-03-3", "DrugBank:DB00434", "Drug_Central:765", "KEGG:C06935", "KEGG:D07765", "LINCS:LSM-5419", "PMID:10843226", "Patent:US3014911", "Wikipedia:Cyproheptadine" ; oboInOwl:hasExactSynonym "4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine", "4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine", "CYPROHEPTADINE", "Cyproheptadine", "cyproheptadine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine", "1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine", "4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine", "4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine", "4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine", "5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene", "ciproheptadina", "cyproheptadine", "cyproheptadinum" ; oboInOwl:id "CHEBI:4046" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyproheptadine" ; rdfs:subClassOf obo:CHEBI_26151, obo:CHEBI_32876, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37955 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48279 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50857 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_55324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59683 ] . obo:CHEBI_41550 chebi:charge "0" ; chebi:formula "CHF3" ; chebi:inchi "InChI=1S/CHF3/c2-1(3)4/h1H" ; chebi:inchikey "XPDWGBQVDMORPB-UHFFFAOYSA-N" ; chebi:mass "70.01385" ; chebi:monoisotopicmass "70.00303" ; chebi:smiles "[H]C(F)(F)F" ; oboInOwl:hasAlternativeId "CHEBI:24073", "CHEBI:41543" ; oboInOwl:hasDbXref "Beilstein:1731035", "CAS:75-46-7", "Gmelin:1543", "PDBeChem:CFT", "UM-BBD_compID:c0802" ; oboInOwl:hasExactSynonym "fluoroform" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CHF3", "Freon 23", "Freon F-23", "TRIFLUOROMETHANE", "carbon trifluoride", "methyl trifluoride" ; oboInOwl:id "CHEBI:41550" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluoroform" ; rdfs:subClassOf obo:CHEBI_39281, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_41609 chebi:charge "-2" ; chebi:formula "CO3" ; chebi:inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2" ; chebi:inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-L" ; chebi:mass "60.00890" ; chebi:monoisotopicmass "59.98584" ; chebi:smiles "[O-]C([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:29201", "CHEBI:41605" ; oboInOwl:hasDbXref "Beilstein:3600898", "CAS:3812-32-6", "Gmelin:1559", "PDBeChem:CO3" ; oboInOwl:hasExactSynonym "carbonate", "trioxidocarbonate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CARBONATE ION", "CO3(2-)", "Karbonat", "[CO3](2-)" ; oboInOwl:id "CHEBI:41609" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbonate" ; rdfs:subClassOf obo:CHEBI_35604, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17544 ] . obo:CHEBI_42485 chebi:charge "0" ; chebi:formula "CHO" ; chebi:mass "29.01804" ; chebi:monoisotopicmass "29.00274" ; chebi:smiles "[H]C(*)=O" ; oboInOwl:hasAlternativeId "CHEBI:24089", "CHEBI:42480" ; oboInOwl:hasDbXref "PDBeChem:FOR" ; oboInOwl:hasExactSynonym "FORMYL GROUP", "aldehyde group", "carbaldehyde", "formyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-CH(O)", "-CHO", "Fo", "H-CO-", "methanoyl" ; oboInOwl:id "CHEBI:42485" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "formyl group" ; rdfs:subClassOf obo:CHEBI_27207, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_30751 ] . obo:CHEBI_4290 chebi:charge "0" ; chebi:formula "C12H19N2.I" ; chebi:inchi "InChI=1S/C12H19N2.HI/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12;/h3-7H,8-11H2,1-2H3;1H/q+1;/p-1" ; chebi:inchikey "XFZJGFIKQCCLGK-UHFFFAOYSA-M" ; chebi:mass "318.19721" ; chebi:monoisotopicmass "318.05929" ; chebi:smiles "[I-].C[N+]1(C)CCN(CC1)c1ccccc1" ; oboInOwl:hasDbXref "Beilstein:3746109", "CAS:54-77-3", "KEGG:C07488" ; oboInOwl:hasExactSynonym "1,1-Dimethyl-4-phenylpiperazinium Iodide", "1,1-dimethyl-4-phenylpiperazinium iodide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1-Dimethyl-4-phenylpiperazine iodide", "DMPP", "DMPP iodide", "Dimethylphenylpiperazinium iodide", "N,N-Dimethyl-N'-phenylpiperazinium iodide" ; oboInOwl:id "CHEBI:4290" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "1,1-dimethyl-4-phenylpiperazinium iodide" ; rdfs:subClassOf obo:CHEBI_35273, obo:CHEBI_46848, obo:CHEBI_46849, obo:CHEBI_50356, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_47958 ] . obo:CHEBI_43176 chebi:charge "0" ; chebi:formula "HO" ; chebi:mass "17.00734" ; chebi:monoisotopicmass "17.00274" ; chebi:smiles "*O[H]" ; oboInOwl:hasAlternativeId "CHEBI:24706", "CHEBI:43171" ; oboInOwl:hasDbXref "PDBeChem:OH" ; oboInOwl:hasExactSynonym "HYDROXY GROUP", "hydroxy", "hydroxy group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-OH", "hydroxyl", "hydroxyl group" ; oboInOwl:id "CHEBI:43176" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydroxy group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:CHEBI_43254 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:43254" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "(4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one" ; rdfs:subClassOf obo:CHEBI_38337, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17568 ] . obo:CHEBI_43451 obo:IAO_0000115 "A diatomic molecule containing covalently bonded hydrogen and iodine atoms." ; chebi:charge "0" ; chebi:formula "HI" ; chebi:inchi "InChI=1S/HI/h1H" ; chebi:inchikey "XMBWDFGMSWQBCA-UHFFFAOYSA-N" ; chebi:mass "127.91241" ; chebi:monoisotopicmass "127.91230" ; chebi:smiles "I[H]" ; oboInOwl:hasAlternativeId "CHEBI:5591" ; oboInOwl:hasDbXref "CAS:10034-85-2", "Gmelin:814", "KEGG:C05590" ; oboInOwl:hasExactSynonym "Hydrogen iodide", "hydrogen iodide", "iodane", "iodidohydrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HI", "Hydrogeniodid", "Hydroiodic acid", "Iodwasserstoff", "Jodwasserstoff", "Wasserstoffiodid", "[HI]", "hydriodic acid", "hydroiodic acid", "iodure d'hydrogene" ; oboInOwl:id "CHEBI:43451" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogen iodide" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_18140, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16382 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_50317 ] . obo:CHEBI_43474 obo:IAO_0000115 "A phosphate ion that is the conjugate base of dihydrogenphosphate." ; chebi:charge "-2" ; chebi:formula "HO4P" ; chebi:inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2" ; chebi:inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-L" ; chebi:mass "95.97930" ; chebi:monoisotopicmass "95.96234" ; chebi:smiles "OP([O-])([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:29139", "CHEBI:43470" ; oboInOwl:hasDbXref "Gmelin:1998", "MolBase:1628", "PDBeChem:PI", "PDBeChem:PO4" ; oboInOwl:hasExactSynonym "hydrogen(tetraoxidophosphate)(2-)", "hydrogenphosphate", "hydrogentetraoxophosphate(2-)", "hydrogentetraoxophosphate(V)", "hydroxidotrioxidophosphate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HPO4(2-)", "HYDROGENPHOSPHATE ION", "INORGANIC PHOSPHATE GROUP", "[P(OH)O3](2-)", "[PO3(OH)](2-)", "hydrogen phosphate", "phosphate" ; oboInOwl:id "CHEBI:43474" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogenphosphate" ; rdfs:subClassOf obo:CHEBI_35780, obo:CHEBI_79388, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_18367 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_39745 ] . obo:CHEBI_43799 obo:IAO_0000115 "A primary aliphatic amine that is butane substituted by an amino group at position 1." ; chebi:charge "0" ; chebi:formula "C4H11N" ; chebi:inchi "InChI=1S/C4H11N/c1-2-3-4-5/h2-5H2,1H3" ; chebi:inchikey "HQABUPZFAYXKJW-UHFFFAOYSA-N" ; chebi:mass "73.13680" ; chebi:monoisotopicmass "73.08915" ; chebi:smiles "CCCCN" ; oboInOwl:hasDbXref "Beilstein:605269", "CAS:109-73-9", "DrugBank:DB03659", "Gmelin:1784", "MetaCyc:BUTYLAMINE", "PDBeChem:LYT", "PMID:16387436", "PMID:23470444", "PMID:23734590", "Reaxys:605269", "Wikipedia:N-Butylamine" ; oboInOwl:hasExactSynonym "butan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-Aminobutan", "1-aminobutane", "1-butanamine", "1-butylamine", "BUTYLAMINE", "butanamine", "butylamine", "mono-n-butylamine", "monobutylamine", "n-Butylamin", "n-C4H9NH2", "n-butylamine" ; oboInOwl:id "CHEBI:43799" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "butan-1-amine" ; rdfs:subClassOf obo:CHEBI_17062 . obo:CHEBI_44423 obo:IAO_0000115 "A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease." ; chebi:charge "0" ; chebi:formula "CH4N2O2" ; chebi:inchi "InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)" ; chebi:inchikey "VSNHCAURESNICA-UHFFFAOYSA-N" ; chebi:mass "76.05474" ; chebi:monoisotopicmass "76.02728" ; chebi:smiles "NC(=O)NO" ; oboInOwl:hasAlternativeId "CHEBI:44420", "CHEBI:5816" ; oboInOwl:hasDbXref "Beilstein:1741548", "CAS:127-07-1", "DrugBank:DB01005", "Drug_Central:1399", "Gmelin:130423", "HMDB:HMDB0015140", "KEGG:C07044", "KEGG:D00341", "MetaCyc:HYDROXY-UREA", "PDBeChem:NHY", "PMID:11285159", "PMID:11298103", "PMID:11364534", "PMID:11365149", "PMID:11391710", "PMID:12107454", "PMID:14988684", "PMID:15772364", "PMID:15994344", "PMID:16356682", "PMID:22983419", "PMID:23318979", "PMID:23643402", "PMID:23696560", "PMID:9271088", "Patent:US2705727", "Reaxys:1741548", "Wikipedia:Hydroxyurea" ; oboInOwl:hasExactSynonym "Hydroxyurea", "N-hydroxyurea", "hydroxyurea" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Hydroxycarbamid", "Hydroxycarbamide", "Hydroxyharnstoff", "N-HYDROXYUREA", "N-carbamoylhydroxylamine", "carbamohydroxamic acid", "carbamohydroximic acid", "carbamoyl oxime", "carbamyl hydroxamate", "hidroxicarbamida", "hydrea", "hydroxycarbamide", "hydroxycarbamidum", "oxyurea" ; oboInOwl:id "CHEBI:44423" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydroxyurea" ; rdfs:subClassOf obo:CHEBI_47857, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35221 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35610 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48578 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50846 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59517 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64911 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_74213 ] . obo:CHEBI_45379 obo:IAO_0000115 "An amino acid consisting of carbamic acid having an N-methyl substituent." ; chebi:charge "0" ; chebi:formula "C2H5NO2" ; chebi:inchi "InChI=1S/C2H5NO2/c1-3-2(4)5/h3H,1H3,(H,4,5)" ; chebi:inchikey "UFEJKYYYVXYMMS-UHFFFAOYSA-N" ; chebi:mass "75.067" ; chebi:monoisotopicmass "75.03203" ; chebi:smiles "CNC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:38464", "CHEBI:45374" ; oboInOwl:hasDbXref "Beilstein:1738994", "CAS:6414-57-9", "PDBeChem:RGI", "PMID:13663920", "PMID:18491873", "PMID:21311787", "PMID:21687849", "PMID:22382393", "PMID:28083911", "PMID:33146910", "Reaxys:1738994" ; oboInOwl:hasExactSynonym "methylcarbamic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Methylcarbamidsaeure", "N-methylcarbamic acid" ; oboInOwl:id "CHEBI:45379" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methylcarbamic acid" ; rdfs:subClassOf obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76976 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_28616 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_193111 ] . obo:CHEBI_45696 chebi:charge "-1" ; chebi:formula "HO4S" ; chebi:inchi "InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-1" ; chebi:inchikey "QAOWNCQODCNURD-UHFFFAOYSA-M" ; chebi:mass "97.07154" ; chebi:monoisotopicmass "96.96010" ; chebi:smiles "[H]OS([O-])(=O)=O" ; oboInOwl:hasAlternativeId "CHEBI:29199", "CHEBI:45693" ; oboInOwl:hasDbXref "Gmelin:2121" ; oboInOwl:hasExactSynonym "hydrogen(tetraoxidosulfate)(1-)", "hydrogensulfate", "hydrogensulfate(1-)", "hydrogentetraoxosulfate(1-)", "hydrogentetraoxosulfate(VI)", "hydroxidotrioxidosulfate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HSO4(-)", "HYDROGEN SULFATE", "[SO3(OH)](-)" ; oboInOwl:id "CHEBI:45696" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogensulfate" ; rdfs:subClassOf obo:CHEBI_33482, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16189 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_26836 ] . obo:CHEBI_46345 obo:IAO_0000115 "A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth." ; chebi:charge "0" ; chebi:formula "C4H3FN2O2" ; chebi:inchi "InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)" ; chebi:inchikey "GHASVSINZRGABV-UHFFFAOYSA-N" ; chebi:mass "130.07730" ; chebi:monoisotopicmass "130.01786" ; chebi:smiles "Fc1c[nH]c(=O)[nH]c1=O" ; oboInOwl:hasAlternativeId "CHEBI:2054", "CHEBI:46343" ; oboInOwl:hasDbXref "Beilstein:127172", "CAS:51-21-8", "DrugBank:DB00544", "Drug_Central:26", "HMDB:HMDB0014684", "KEGG:C07649", "KEGG:D00584", "LINCS:LSM-4261", "PDBeChem:URF", "PMID:11356943", "PMID:12520460", "PMID:14769231", "PMID:19023200", "Reaxys:127172", "Wikipedia:Fluorouracil" ; oboInOwl:hasExactSynonym "5-Fluorouracil", "5-fluoropyrimidine-2,4(1H,3H)-dione", "5-fluorouracil" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-FU", "5-Fluoracil", "5-Fluoropyrimidine-2,4-dione", "Fluorouracil", "fluorouracil", "fluorouracilo", "fluorouracilum" ; oboInOwl:id "CHEBI:46345" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "5-fluorouracil" ; rdfs:subClassOf obo:CHEBI_37143, obo:CHEBI_67142, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_132992 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35221 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35610 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35705 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17568 ] . obo:CHEBI_46629 chebi:charge "0" ; chebi:formula "O" ; chebi:mass "15.99940" ; chebi:monoisotopicmass "15.99491" ; chebi:smiles "O=*" ; oboInOwl:hasAlternativeId "CHEBI:29353", "CHEBI:44607" ; oboInOwl:hasDbXref "PDBeChem:O" ; oboInOwl:hasExactSynonym "OXO GROUP", "oxo" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "=O" ; oboInOwl:id "CHEBI:46629" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxo group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:CHEBI_46640 obo:IAO_0000115 "A compound that contains two ketone functionalities." ; oboInOwl:hasDbXref "Wikipedia:Diketone" ; oboInOwl:hasExactSynonym "diketones" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:46640" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_46695 obo:IAO_0000115 "A compound derived from a hydrocarbon by replacing one or more hydrogen atoms with fluorine atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "FKW", "Fluorkohlenwasserstoffe", "HFC", "fluorohydrocarbons" ; oboInOwl:id "CHEBI:46695" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluorohydrocarbon" ; rdfs:subClassOf obo:CHEBI_24472, obo:CHEBI_37143 . obo:CHEBI_46775 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-alkylpyrrolidines" ; oboInOwl:id "CHEBI:46775" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "N-alkylpyrrolidine" ; rdfs:subClassOf obo:CHEBI_38260, obo:CHEBI_50996 . obo:CHEBI_46787 obo:IAO_0000115 "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." ; oboInOwl:hasDbXref "Wikipedia:Solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Loesungsmittel", "solvant", "solvents" ; oboInOwl:id "CHEBI:46787" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "solvent" ; rdfs:subClassOf obo:CHEBI_33232, obo:CHEBI_51086 . obo:CHEBI_46800 chebi:charge "0" ; chebi:formula "C2H4OS" ; chebi:inchi "InChI=1S/C2H4OS/c1-2(3)4/h1H3,(H,3,4)" ; chebi:inchikey "DUYAAUVXQSMXQP-UHFFFAOYSA-N" ; chebi:mass "76.11856" ; chebi:monoisotopicmass "75.99829" ; chebi:smiles "CC(O)=S" ; oboInOwl:hasDbXref "Beilstein:1733298", "Gmelin:1216872" ; oboInOwl:hasExactSynonym "ethanethioic O-acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:46800" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ethanethioic O-acid" ; rdfs:subClassOf obo:CHEBI_26952, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16555 ] . obo:CHEBI_46845 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-alkylpiperazines" ; oboInOwl:id "CHEBI:46845" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "N-alkylpiperazine" ; rdfs:subClassOf obo:CHEBI_26144, obo:CHEBI_50996 . obo:CHEBI_46848 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-arylpiperazines" ; oboInOwl:id "CHEBI:46848" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "N-arylpiperazine" ; rdfs:subClassOf obo:CHEBI_26144, obo:CHEBI_33860, obo:CHEBI_50996 . obo:CHEBI_46849 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "piperazinium salts" ; oboInOwl:id "CHEBI:46849" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "piperazinium salt" ; rdfs:subClassOf obo:CHEBI_46850 . obo:CHEBI_46850 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organoammonium salts" ; oboInOwl:id "CHEBI:46850" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organoammonium salt" ; rdfs:subClassOf obo:CHEBI_35276 . obo:CHEBI_46883 chebi:charge "0" ; chebi:formula "CHO2" ; chebi:mass "45.01744" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "*C(=O)O" ; oboInOwl:hasAlternativeId "CHEBI:23025", "CHEBI:41420" ; oboInOwl:hasDbXref "PDBeChem:FMT" ; oboInOwl:hasExactSynonym "CARBOXY GROUP", "carboxy" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-C(O)OH", "-CO2H", "-COOH", "carboxyl group" ; oboInOwl:id "CHEBI:46883" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carboxy group" ; rdfs:subClassOf obo:CHEBI_33249 . obo:CHEBI_46997 obo:IAO_0000115 "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in L-glyceraldehyde." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:mass "150.130" ; chebi:monoisotopicmass "150.05282" ; oboInOwl:hasExactSynonym "L-ribo-pentose", "L-ribose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-Rib" ; oboInOwl:id "CHEBI:46997" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-ribose" ; rdfs:subClassOf obo:CHEBI_33942, [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_16988 ] . obo:CHEBI_46998 obo:IAO_0000115 "A cyclic ribose having a 5-membered tetrahydrofuran ring; the predominant (C3'-endo) form of the two cyclic structures (the other is the \"C2'-endo\" form, having a 6-membered ring) adopted by ribose in aqueous solution." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:mass "150.12990" ; chebi:monoisotopicmass "150.05282" ; oboInOwl:hasExactSynonym "ribofuranose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "rel-(3R,4S,5R)-5-(hydroxymethyl)tetrahydrofuran-2,3,4-triol" ; oboInOwl:id "CHEBI:46998" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribofuranose" ; rdfs:subClassOf obo:CHEBI_33942, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84735 ] . obo:CHEBI_47013 obo:IAO_0000115 "A ribofuranose having D-configuration." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:inchi "InChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5?/m1/s1" ; chebi:inchikey "HMFHBZSHGGEWLO-SOOFDHNKSA-N" ; chebi:mass "150.12990" ; chebi:monoisotopicmass "150.05282" ; chebi:smiles "OC[C@H]1OC(O)[C@H](O)[C@@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:4233", "CHEBI:46999" ; oboInOwl:hasDbXref "Beilstein:1904878", "CAS:50-69-1", "CAS:613-83-2", "GlyGen:G31080DL", "GlyTouCan:G31080DL", "Gmelin:364108", "KEGG:C00121", "PMID:9506998", "Patent:US2152662", "Reaxys:1904878" ; oboInOwl:hasExactSynonym "D-ribofuranose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(3R,4S,5R)-5-(hydroxymethyl)tetrahydrofuran-2,3,4-triol", "D-Ribose", "D-ribose", "WURCS=2.0/1,1,0/[a222h-1x_1-4]/1/", "ribose" ; oboInOwl:id "CHEBI:47013" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-ribofuranose" ; rdfs:subClassOf obo:CHEBI_16988, obo:CHEBI_46998 . obo:CHEBI_47017 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tetrahydrofuranols" ; oboInOwl:id "CHEBI:47017" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tetrahydrofuranol" ; rdfs:subClassOf obo:CHEBI_26912 . obo:CHEBI_47019 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dihydroxytetrahydrofurans" ; oboInOwl:id "CHEBI:47019" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dihydroxytetrahydrofuran" ; rdfs:subClassOf obo:CHEBI_47017 . obo:CHEBI_47266 obo:IAO_0000115 "A diatomic molecule containing covalently bonded hydrogen and bromine atoms." ; chebi:charge "0" ; chebi:formula "BrH", "HBr" ; chebi:inchi "InChI=1S/BrH/h1H" ; chebi:inchikey "CPELXLSAUQHCOX-UHFFFAOYSA-N" ; chebi:mass "80.91194" ; chebi:monoisotopicmass "79.92616" ; chebi:smiles "Br[H]" ; oboInOwl:hasAlternativeId "CHEBI:29134", "CHEBI:31673" ; oboInOwl:hasDbXref "CAS:10035-10-6", "Gmelin:620", "KEGG:C13645" ; oboInOwl:hasExactSynonym "bromane", "bromidohydrogen", "hydrogen bromide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bromwasserstoff", "HBr", "Hydrobromic acid", "Hydrogenbromid", "[HBr]", "bromure d'hydrogene" ; oboInOwl:id "CHEBI:47266" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogen bromide" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_18140, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15858 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_50316 ] . obo:CHEBI_472805 obo:IAO_0000115 "A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus." ; chebi:charge "0" ; chebi:formula "C29H44O12" ; chebi:inchi "InChI=1S/C29H44O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1" ; chebi:inchikey "LPMXVESGRSUGHW-HBYQJFLCSA-N" ; chebi:mass "584.65250" ; chebi:monoisotopicmass "584.28328" ; chebi:smiles "[H][C@@]12CC[C@]3(O)C[C@H](C[C@@H](O)[C@]3(CO)[C@@]1([H])[C@H](O)C[C@]1(C)[C@H](CC[C@]21O)C1=CC(=O)OC1)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:44461", "CHEBI:7805" ; oboInOwl:hasDbXref "Beilstein:101712", "CAS:630-60-4", "DrugBank:DB01092", "Drug_Central:2004", "FooDB:FDB005482", "HMDB:HMDB0015224", "KEGG:C01443", "KEGG:D00112", "KNApSAcK:C00003633", "LINCS:LSM-2781", "LIPID_MAPS_instance:LMST01120022", "PDBeChem:OBN", "PMID:10438974", "PMID:1316269", "PMID:16529963", "PMID:20372980", "PMID:31075189", "PMID:31170971", "PMID:31548455", "PMID:31986323", "PMID:32326025", "PMID:32368275", "PMID:32488807", "PMID:32569558", "PMID:9872395", "Reaxys:101712", "Wikipedia:Ouabain" ; oboInOwl:hasExactSynonym "3-(6-deoxy-alpha-L-mannopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide", "Ouabain" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3-(alpha-L-rhamnopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide", "G-Strophanthin", "Ouabagenin L-Rhamnoside", "Ouabagenin-L-rhamnosid", "Ouabain anhydrous", "Ouabaine", "Oubain", "Strodival" ; oboInOwl:id "CHEBI:472805" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ouabain" ; rdfs:subClassOf obo:CHEBI_19129, obo:CHEBI_26764, obo:CHEBI_27848, obo:CHEBI_36862, obo:CHEBI_38092, obo:CHEBI_38195, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38070 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38147 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_49200 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50184 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63510 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77023 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77024 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_145798 ] . obo:CHEBI_47499 obo:IAO_0000115 "A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom." ; chebi:charge "0" ; chebi:formula "C19H24N2" ; chebi:inchi "InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3" ; chebi:inchikey "BCGWQEUPMDMJNV-UHFFFAOYSA-N" ; chebi:mass "280.40734" ; chebi:monoisotopicmass "280.19395" ; chebi:smiles "CN(C)CCCN1c2ccccc2CCc2ccccc12" ; oboInOwl:hasAlternativeId "CHEBI:47498", "CHEBI:5881" ; oboInOwl:hasDbXref "Beilstein:256892", "CAS:50-49-7", "DrugBank:DB00458", "Drug_Central:1427", "Gmelin:1572523", "HMDB:HMDB0001848", "KEGG:C07049", "KEGG:D08070", "LINCS:LSM-2852", "PDBeChem:IXX", "PMID:20825390", "Patent:US2554736", "Reaxys:256892", "Wikipedia:Imipramine" ; oboInOwl:hasExactSynonym "3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine", "Imipramine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine", "3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE", "5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine", "Antideprin", "Imipramin", "Irmin", "Melipramine", "N-(gamma-dimethylaminopropyl)iminodibenzyl", "imipramine", "imipraminum", "imizine" ; oboInOwl:id "CHEBI:47499" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "imipramine" ; rdfs:subClassOf obo:CHEBI_47804, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35640 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76779 ], [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_47802 ] . obo:CHEBI_47622 obo:IAO_0000115 "Any carboxylic ester where the carboxylic acid component is acetic acid." ; chebi:charge "0" ; chebi:formula "C2H3O2R" ; chebi:mass "59.04400" ; chebi:monoisotopicmass "59.01330" ; chebi:smiles "CC(=O)O[*]" ; oboInOwl:hasAlternativeId "CHEBI:13244", "CHEBI:13799", "CHEBI:22189", "CHEBI:2406" ; oboInOwl:hasDbXref "KEGG:C01883", "Wikipedia:Acetate#Esters" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Acetic ester", "Acetyl ester", "acetate", "acetate esters", "acetates", "acetyl esters", "an acetyl ester" ; oboInOwl:id "CHEBI:47622" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acetate ester" ; rdfs:subClassOf obo:CHEBI_33308, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_15366 ] . obo:CHEBI_47704 oboInOwl:hasExactSynonym "ammonium salt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ammoniumsalz", "Ammoniumsalze", "ammonium salts" ; oboInOwl:id "CHEBI:47704" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ammonium salt" ; rdfs:subClassOf obo:CHEBI_35276, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_28938 ] . obo:CHEBI_47802 obo:IAO_0000115 "A mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings." ; chebi:charge "0" ; chebi:formula "C14H11N" ; chebi:inchi "InChI=1S/C14H11N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-10,15H" ; chebi:inchikey "LCGTWRLJTMHIQZ-UHFFFAOYSA-N" ; chebi:mass "193.249" ; chebi:monoisotopicmass "193.08915" ; chebi:smiles "N1C2=C(C=CC=C2)C=CC2=C1C=CC=C2" ; oboInOwl:hasDbXref "Beilstein:1343358", "CAS:256-96-2", "Chemspider:8857", "PDBeChem:ONB", "PMID:11767950", "PMID:12052500", "PMID:12061877", "PMID:15837018", "PMID:16203183", "PMID:17236778", "PMID:18779941", "PMID:19486265", "PMID:19774656", "PMID:20922935", "PMID:21087114", "PMID:21441615", "PMID:22322005", "PMID:22751668", "PMID:2322636", "PMID:24358274", "PMID:27175105", "PMID:27389944", "PMID:27807790", "PMID:30660838", "PMID:30754023", "PMID:30823329", "PMID:31718245", "PMID:33381027", "PMID:33842007", "PMID:3680120", "PMID:4146691", "PMID:5982986", "PMID:7587936", "PMID:8385460", "PMID:870507", "Reaxys:1343358", "Wikipedia:Dibenzazepine" ; oboInOwl:hasExactSynonym "5H-dibenzo[b,f]azepine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,2'-iminostilbene", "2,3,6,7-dibenzazepine", "5H-Dibenz[b,f]azepin", "5H-dibenz[b,f]azepine", "5H-dibenzazepine", "dibenz(b,f)azepine", "dibenzazepine", "iminostilbene", "o,o'-iminostilbene" ; oboInOwl:id "CHEBI:47802" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "5H-dibenzo[b,f]azepine" ; rdfs:subClassOf obo:CHEBI_36416, obo:CHEBI_47804, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83399 ] . obo:CHEBI_47804 oboInOwl:hasExactSynonym "dibenzoazepine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dibenzazepine", "dibenzoazepines" ; oboInOwl:id "CHEBI:47804" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dibenzoazepine" ; rdfs:subClassOf obo:CHEBI_26979, obo:CHEBI_38101 . obo:CHEBI_4781 obo:IAO_0000115 "A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties." ; chebi:charge "0" ; chebi:formula "C29H40N2O4" ; chebi:inchi "InChI=1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1" ; chebi:inchikey "AUVVAXYIELKVAI-CKBKHPSWSA-N" ; chebi:mass "480.63898" ; chebi:monoisotopicmass "480.29881" ; chebi:smiles "[H][C@]1(C[C@@]2([H])NCCc3cc(OC)c(OC)cc23)C[C@]2([H])N(CCc3cc(OC)c(OC)cc23)C[C@@H]1CC" ; oboInOwl:hasDbXref "Beilstein:100834", "Beilstein:6253162", "CAS:483-18-1", "DrugBank:DB13393", "Drug_Central:1001", "KEGG:C09421", "KNApSAcK:C00001849", "LINCS:LSM-2041", "MetaCyc:CPD-14817", "PMID:14119536", "PMID:16109351", "PMID:17094176", "PMID:19227966", "PMID:29872540", "PMID:31436297", "PMID:31533472", "PMID:31734270", "PMID:31775307", "PMID:31964796", "PMID:32245264", "PMID:32251767", "Reaxys:100834", "Wikipedia:Emetine" ; oboInOwl:hasExactSynonym "6',7',10,11-tetramethoxyemetan", "Emetine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Emetan", "Emetin", "cephaeline methyl ether", "cephaline-O-methyl ether", "methyl cephaeline" ; oboInOwl:id "CHEBI:4781" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "emetine" ; rdfs:subClassOf obo:CHEBI_24921, obo:CHEBI_61692, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149552 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149553 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_171664 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35610 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77035 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_88230 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_3533 ], [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_36380 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_149548 ] . obo:CHEBI_47857 oboInOwl:hasAlternativeId "CHEBI:27220", "CHEBI:36947" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "urea derivatives" ; oboInOwl:id "CHEBI:47857" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ureas" ; rdfs:subClassOf obo:CHEBI_33256, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16199 ] . obo:CHEBI_47867 obo:IAO_0000115 "Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Indikator" ; oboInOwl:id "CHEBI:47867" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "indicator" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_47882 oboInOwl:hasExactSynonym "macrocyclic polypyrroles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic polypyrroles", "polypyrrole macrocycles" ; oboInOwl:id "CHEBI:47882" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic polypyrrole" ; rdfs:subClassOf obo:CHEBI_38077 . obo:CHEBI_47891 obo:IAO_0000115 "Any steroid substituted by at least one carboxy group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "steroid acids" ; oboInOwl:id "CHEBI:47891" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "steroid acid" ; rdfs:subClassOf obo:CHEBI_35341, obo:CHEBI_64709, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_50160 ] . obo:CHEBI_47901 obo:IAO_0000115 "Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an alkyl group." ; oboInOwl:hasAlternativeId "CHEBI:13809", "CHEBI:33553" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkanesulfonic acids", "alkylsulfonic acids" ; oboInOwl:id "CHEBI:47901" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkanesulfonic acid" ; rdfs:subClassOf obo:CHEBI_33551, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22323 ] . obo:CHEBI_4792 obo:IAO_0000115 "An ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups." ; chebi:charge "0" ; chebi:formula "C3H2ClF5O" ; chebi:inchi "InChI=1S/C3H2ClF5O/c4-1(5)3(8,9)10-2(6)7/h1-2H" ; chebi:inchikey "JPGQOUSTVILISH-UHFFFAOYSA-N" ; chebi:mass "184.49210" ; chebi:monoisotopicmass "183.97143" ; chebi:smiles "FC(F)OC(F)(F)C(F)Cl" ; oboInOwl:hasDbXref "Beilstein:1903921", "CAS:13838-16-9", "DrugBank:DB00228", "Drug_Central:1009", "HMDB:HMDB0014373", "KEGG:C07516", "KEGG:D00543", "PMID:23934553", "PMID:25386744", "PMID:7457058", "Patent:AU2014277860", "Patent:US5783199", "Reaxys:1903921", "Wikipedia:Enflurane" ; oboInOwl:hasExactSynonym "2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane", "Enflurane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-chloro-1,1,2-trifluoroethyl difluoromethyl ether", "Alyrane", "Efrane", "Ethrane", "Methylflurether" ; oboInOwl:id "CHEBI:4792" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "enflurane" ; rdfs:subClassOf obo:CHEBI_25698, obo:CHEBI_36683, obo:CHEBI_37143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38867 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_39832 ] . obo:CHEBI_47923 obo:IAO_0000115 "Any oligopeptide that consists of three amino-acid residues connected by peptide linkages." ; chebi:charge "0" ; chebi:formula "C6H8N3O4R3" ; chebi:mass "186.146" ; chebi:monoisotopicmass "186.05148" ; chebi:smiles "C(=O)(NC(C(NC(C(=O)O)*)=O)*)C(N)*" ; oboInOwl:hasAlternativeId "CHEBI:27138", "CHEBI:9742" ; oboInOwl:hasDbXref "KEGG:C00316", "Wikipedia:Tripeptide" ; oboInOwl:hasExactSynonym "Tripeptide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tripeptides" ; oboInOwl:id "CHEBI:47923" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tripeptide" ; rdfs:subClassOf obo:CHEBI_25676, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_155837 ] . obo:CHEBI_47958 obo:IAO_0000115 "An agonist that selectively binds to and activates a nicotinic acetylcholine receptor." ; oboInOwl:hasAlternativeId "CHEBI:82738" ; oboInOwl:hasDbXref "Wikipedia:Nicotinic_acetylcholine_receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "muscarinic agonists", "nicotinic acetylcholine receptor agonists", "nicotinic agonist", "nicotinic agonists" ; oboInOwl:id "CHEBI:47958" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nicotinic acetylcholine receptor agonist" ; rdfs:subClassOf obo:CHEBI_38324 . obo:CHEBI_48001 obo:IAO_0000115 "A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "protein synthesis antagonist", "protein synthesis antagonists", "protein synthesis inhibitors" ; oboInOwl:id "CHEBI:48001" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "protein synthesis inhibitor" ; rdfs:subClassOf obo:CHEBI_76932 . obo:CHEBI_48154 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Schwefeloxide", "oxides of sulfur", "sulfur oxides" ; oboInOwl:id "CHEBI:48154" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur oxide" ; rdfs:subClassOf obo:CHEBI_24836, obo:CHEBI_26835 . obo:CHEBI_48218 obo:IAO_0000115 "A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body)." ; oboInOwl:hasDbXref "Wikipedia:Antiseptic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antiseptic", "antiseptic agent", "antiseptic agents", "antiseptics", "local antiinfective agents", "local microbicides", "topical antiinfective agents", "topical microbicides" ; oboInOwl:id "CHEBI:48218" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antiseptic drug" ; rdfs:subClassOf obo:CHEBI_35441 . obo:CHEBI_48219 obo:IAO_0000115 "An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Desinfektionsmittel", "desinfectant", "disinfectants", "disinfecting agent" ; oboInOwl:id "CHEBI:48219" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "disinfectant" ; rdfs:subClassOf obo:CHEBI_33281 . obo:CHEBI_48278 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "serotonergic agents", "serotonergic drugs", "serotonin drugs" ; oboInOwl:id "CHEBI:48278" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "serotonergic drug" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_48279 obo:IAO_0000115 "Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-HT antagonists", "5-hydroxytryptamine antagonists", "antiserotonergic agents", "serotonin antagonists", "serotonin blockaders" ; oboInOwl:id "CHEBI:48279" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "serotonergic antagonist" ; rdfs:subClassOf obo:CHEBI_48278 . obo:CHEBI_48354 obo:IAO_0000115 "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." ; oboInOwl:hasExactSynonym "polar solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polar solvents" ; oboInOwl:id "CHEBI:48354" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polar solvent" ; rdfs:subClassOf obo:CHEBI_46787 . obo:CHEBI_48355 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48355" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "non-polar solvent" ; rdfs:subClassOf obo:CHEBI_46787 . obo:CHEBI_48356 obo:IAO_0000115 "A polar solvent that is capable of acting as a hydron (proton) donor." ; oboInOwl:hasExactSynonym "protogenic solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48356" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "protic solvent" ; rdfs:subClassOf obo:CHEBI_39141, obo:CHEBI_48354 . obo:CHEBI_48357 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48357" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "aprotic solvent" ; rdfs:subClassOf obo:CHEBI_46787 . obo:CHEBI_48358 obo:IAO_0000115 "A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds." ; oboInOwl:hasExactSynonym "dipolar aprotic solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48358" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polar aprotic solvent" ; rdfs:subClassOf obo:CHEBI_48354, obo:CHEBI_48357 . obo:CHEBI_48359 obo:IAO_0000115 "Solvent that is capable of acting as a hydron (proton) acceptor." ; oboInOwl:hasExactSynonym "protophilic solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HBA solvent", "hydrogen bond acceptor solvent" ; oboInOwl:id "CHEBI:48359" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "protophilic solvent" ; rdfs:subClassOf obo:CHEBI_39142, obo:CHEBI_48354 . obo:CHEBI_48360 obo:IAO_0000115 "Self-ionizing solvent possessing both characteristics of Bronsted acids and bases." ; oboInOwl:hasExactSynonym "amphiprotic solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48360" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amphiprotic solvent" ; rdfs:subClassOf obo:CHEBI_48356, obo:CHEBI_48359 . obo:CHEBI_48376 chebi:charge "0" ; chebi:formula "CH4N2O" ; chebi:inchi "InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)" ; chebi:inchikey "XSQUKJJJFZCRTK-UHFFFAOYSA-N" ; chebi:mass "60.05534" ; chebi:monoisotopicmass "60.03236" ; chebi:smiles "NC(O)=N" ; oboInOwl:hasDbXref "Beilstein:773698", "CAS:4744-36-9" ; oboInOwl:hasExactSynonym "carbamimidic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2N-C(=NH)-OH", "H2N-C(OH)=NH", "HO-C(=NH)-NH2", "Isoharnstoff", "carbamimic acid", "carbonamidimidic acid", "isourea", "pseudourea" ; oboInOwl:id "CHEBI:48376" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbamimidic acid" ; rdfs:subClassOf obo:CHEBI_48379, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16199 ] . obo:CHEBI_48377 obo:IAO_0000115 "Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH)." ; oboInOwl:hasExactSynonym "imidic acid", "imidic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "imidic acids", "imino acids" ; oboInOwl:id "CHEBI:48377" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "imidic acid" ; rdfs:subClassOf obo:CHEBI_33241, obo:CHEBI_51143 . obo:CHEBI_48378 oboInOwl:hasExactSynonym "carboximidic acid", "carboximidic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carboximidic acids" ; oboInOwl:id "CHEBI:48378" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carboximidic acid" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_48377 . obo:CHEBI_48379 obo:IAO_0000115 "A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives." ; oboInOwl:hasExactSynonym "isoureas" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isoureas" ; oboInOwl:id "CHEBI:48379" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isourea" ; rdfs:subClassOf obo:CHEBI_48378 . obo:CHEBI_48539 obo:IAO_0000115 "Any drug that acts on an alpha-adrenergic receptor." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-adrenergic drugs" ; oboInOwl:id "CHEBI:48539" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-adrenergic drug" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_48540 obo:IAO_0000115 "Any of the drugs that act on beta-adrenergic receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "beta-adrenergic drugs" ; oboInOwl:id "CHEBI:48540" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "beta-adrenergic drug" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_48544 obo:IAO_0000115 "Esters or salts of methanesulfonic acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48544" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methanesulfonates" ; rdfs:subClassOf obo:CHEBI_33261, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_27376 ] . obo:CHEBI_48560 obo:IAO_0000115 "A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dopamine agent", "dopamine agents", "dopamine drug", "dopamine drugs", "dopaminergic agents" ; oboInOwl:id "CHEBI:48560" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dopaminergic agent" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_48561 obo:IAO_0000115 "A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dopamine antagonist", "dopamine blocker", "dopamine receptor antagonist", "dopaminergic antagonists" ; oboInOwl:id "CHEBI:48561" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dopaminergic antagonist" ; rdfs:subClassOf obo:CHEBI_48560, obo:CHEBI_48706 . obo:CHEBI_48578 obo:IAO_0000115 "A role played by a substance that can react readily with, and thereby eliminate, radicals." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "free radical scavengers", "free-radical scavenger" ; oboInOwl:id "CHEBI:48578" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "radical scavenger" ; rdfs:subClassOf obo:CHEBI_22586 . obo:CHEBI_48705 obo:IAO_0000115 "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." ; oboInOwl:hasExactSynonym "agonist" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agonista", "agoniste", "agonists" ; oboInOwl:id "CHEBI:48705" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "agonist" ; rdfs:subClassOf obo:CHEBI_52210 . obo:CHEBI_48706 obo:IAO_0000115 "Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances." ; oboInOwl:hasExactSynonym "antagonist" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antagonista", "antagoniste", "antagonists" ; oboInOwl:id "CHEBI:48706" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antagonist" ; rdfs:subClassOf obo:CHEBI_52210 . obo:CHEBI_48854 chebi:charge "0" ; chebi:formula "H2O3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)" ; chebi:inchikey "LSNNMFCWUKXFEE-UHFFFAOYSA-N" ; chebi:mass "82.08008" ; chebi:monoisotopicmass "81.97247" ; chebi:smiles "OS(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:26837", "CHEBI:9344" ; oboInOwl:hasDbXref "CAS:7782-99-2", "Gmelin:1458", "KEGG:C00094", "KNApSAcK:C00019662", "PDBeChem:SO3", "UM-BBD_compID:c0348" ; oboInOwl:hasExactSynonym "Sulfurous acid", "dihydrogen trioxosulfate", "dihydroxidooxidosulfur", "sulfurous acid", "trioxosulfuric acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2SO3", "S(O)(OH)2", "Sulfite", "[SO(OH)2]", "acide sulfureux", "acido sulfuroso", "schweflige Saeure", "sulphurous acid" ; oboInOwl:id "CHEBI:48854" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfurous acid" ; rdfs:subClassOf obo:CHEBI_33402, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17137 ], [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_29214 ] . obo:CHEBI_4887 obo:IAO_0000115 "A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures." ; chebi:charge "0" ; chebi:formula "C7H11NO2" ; chebi:inchi "InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)" ; chebi:inchikey "HAPOVYFOVVWLRS-UHFFFAOYSA-N" ; chebi:mass "141.16770" ; chebi:monoisotopicmass "141.07898" ; chebi:smiles "CCC1(C)CC(=O)NC1=O" ; oboInOwl:hasAlternativeId "CHEBI:131811" ; oboInOwl:hasDbXref "CAS:77-67-8", "Chemspider:3175", "DrugBank:DB00593", "Drug_Central:1087", "HMDB:HMDB0014731", "KEGG:C07505", "KEGG:D00539", "LINCS:LSM-5195", "PMID:12873507", "PMID:16606760", "PMID:1681105", "PMID:17011080", "PMID:17046248", "PMID:17451232", "PMID:17481896", "PMID:1847429", "PMID:18949032", "PMID:19005061", "PMID:1992141", "PMID:2061925", "PMID:21332949", "PMID:21945797", "PMID:2296016", "PMID:2308142", "PMID:3336019", "PMID:3820228", "PMID:8246220", "PMID:8627613", "PMID:8691481", "PMID:9016327", "Reaxys:117054", "Wikipedia:Ethosuximide" ; oboInOwl:hasExactSynonym "3-ethyl-3-methylpyrrolidine-2,5-dione", "Ethosuximide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+-)-2-ethyl-2-methylsuccinimide", "2-ethyl-2-methylsuccinimide", "2-methyl-2-ethylsuccinimide", "3-ethyl-3-methyl-2,5-pyrrolidinedione", "3-ethyl-3-methylsuccinimide", "3-methyl-3-ethylpyrrolidine-2,5-dione", "3-methyl-3-ethylsuccinimide", "Aethosuximide", "alpha-ethyl-alpha-methylsuccinimide", "alpha-methyl-alpha-ethylsuccinimide", "ethosuximide", "ethosuximidum", "etosuximida", "gamma-ethyl-gamma-methyl-succinimide", "gamma-methyl-gamma-ethyl-succinimide" ; oboInOwl:id "CHEBI:4887" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ethosuximide" ; rdfs:subClassOf obo:CHEBI_35356, obo:CHEBI_38275, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_194338 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35623 ] . obo:CHEBI_48909 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "imidazothiazoles" ; oboInOwl:id "CHEBI:48909" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "imidazothiazole" ; rdfs:subClassOf obo:CHEBI_27171, obo:CHEBI_38101, obo:CHEBI_38106 . obo:CHEBI_48975 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "substituted anilines" ; oboInOwl:id "CHEBI:48975" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "substituted aniline" ; rdfs:subClassOf obo:CHEBI_22562 . obo:CHEBI_49110 obo:IAO_0000115 "A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "peripheral nervous system agent", "peripheral nervous system drugs" ; oboInOwl:id "CHEBI:49110" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "peripheral nervous system drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_49200 obo:IAO_0000115 "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H(+)/K(+)-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors." ; oboInOwl:hasDbXref "Wikipedia:Proton_pump_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(K(+) + H(+))-ATPase inhibitor", "(K(+) + H(+))-ATPase inhibitors", "ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitor", "ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitors", "EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitors", "EC 3.6.3.10 inhibitor", "EC 3.6.3.10 inhibitors", "H(+)-K(+)-ATPase inhibitor", "H(+)-K(+)-ATPase inhibitors", "H(+)/K(+)-ATPase inhibitor", "H(+)/K(+)-ATPase inhibitors", "H(+)/K(+)-exchanging ATPase inhibitor", "H(+)/K(+)-exchanging ATPase inhibitors", "H,K-ATPase inhibitor", "H,K-ATPase inhibitors", "proton pump inhibitor", "proton pump inhibitors" ; oboInOwl:id "CHEBI:49200" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76895 . obo:CHEBI_49637 chebi:charge "0" ; chebi:formula "H" ; chebi:inchi "InChI=1S/H" ; chebi:inchikey "YZCKVEUIGOORGS-UHFFFAOYSA-N" ; chebi:mass "1.00794" ; chebi:monoisotopicmass "1.00783" ; chebi:smiles "[H]" ; oboInOwl:hasAlternativeId "CHEBI:24634", "CHEBI:49636" ; oboInOwl:hasDbXref "WebElements:H" ; oboInOwl:hasExactSynonym "hydrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1H", "H", "Wasserstoff", "hidrogeno", "hydrogen", "hydrogene" ; oboInOwl:id "CHEBI:49637" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydrogen atom" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_25585, obo:CHEBI_33559, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_49870 chebi:charge "0" ; chebi:formula "H3O3Sb" ; chebi:inchi "InChI=1S/3H2O.Sb/h3*1H2;/q;;;+3/p-3" ; chebi:inchikey "SZOADBKOANDULT-UHFFFAOYSA-K" ; chebi:mass "172.78202" ; chebi:monoisotopicmass "171.91203" ; chebi:smiles "[H]O[Sb](O[H])O[H]" ; oboInOwl:hasAlternativeId "CHEBI:30296", "CHEBI:49869" ; oboInOwl:hasDbXref "DrugBank:DB02453", "Gmelin:558348", "PDBeChem:SBO" ; oboInOwl:hasExactSynonym "antimonous acid", "trihydroxidoantimony" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H3SbO3", "TRIHYDROXYANTIMONITE(III)", "[Sb(OH)3]", "stiborous acid" ; oboInOwl:id "CHEBI:49870" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimonous acid" ; rdfs:subClassOf obo:CHEBI_36920, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30297 ] . obo:CHEBI_50007 oboInOwl:hasExactSynonym "antimony coordination entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimony coordination compounds", "antimony coordination entities" ; oboInOwl:id "CHEBI:50007" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimony coordination entity" ; rdfs:subClassOf obo:CHEBI_36919 . obo:CHEBI_50047 obo:IAO_0000115 "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic amino compounds" ; oboInOwl:id "CHEBI:50047" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic amino compound" ; rdfs:subClassOf obo:CHEBI_35352, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39142 ], [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_16134 ] . obo:CHEBI_50112 obo:IAO_0000115 "Any hormone that is responsible for controlling sexual characteristics and reproductive function." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Geschlechtshormon", "Geschlechtshormone", "Sexualhormon", "Sexualhormone", "hormone sexuelle", "hormones sexuelles", "sex hormones" ; oboInOwl:id "CHEBI:50112" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sex hormone" ; rdfs:subClassOf obo:CHEBI_24621 . obo:CHEBI_50114 obo:IAO_0000115 "A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens." ; oboInOwl:hasDbXref "Wikipedia:Estrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Estrogene", "Oestrogen", "Oestrogene", "estrogene", "estrogenes", "estrogenes Hormon", "estrogeno", "estrogenos", "estrogens", "oestrogen", "oestrogene", "oestrogenes", "oestrogens" ; oboInOwl:id "CHEBI:50114" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "estrogen" ; rdfs:subClassOf obo:CHEBI_50112 . obo:CHEBI_50127 chebi:charge "0" ; chebi:formula "CF3" ; chebi:mass "69.00591" ; chebi:monoisotopicmass "68.99521" ; chebi:smiles "C(F)(*)(F)F" ; oboInOwl:hasExactSynonym "trifluoromethyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-CF3" ; oboInOwl:id "CHEBI:50127" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "trifluoromethyl group" ; rdfs:subClassOf obo:CHEBI_50491, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_38825 ], [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_41550 ] . obo:CHEBI_50160 obo:IAO_0000115 "Any anion formed by loss of a proton from a steroid acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "steroid acid anions" ; oboInOwl:id "CHEBI:50160" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "steroid acid anion" ; rdfs:subClassOf obo:CHEBI_29067, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_47891 ] . obo:CHEBI_50177 obo:IAO_0000115 "A drug used to treat or prevent skin disorders or for the routine care of skin." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dermatologic agent", "dermatologic drugs", "dermatological agent" ; oboInOwl:id "CHEBI:50177" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dermatologic drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_50184 obo:IAO_0000115 "A compound which inhibits the movement of an ion across an energy-transducing cell membrane." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ion transport inhibitors", "ion-transport inhibitor", "ion-transport inhibitors" ; oboInOwl:id "CHEBI:50184" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ion transport inhibitor" ; rdfs:subClassOf obo:CHEBI_38632 . obo:CHEBI_50218 obo:IAO_0000115 "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*)." ; oboInOwl:hasAlternativeId "CHEBI:76774" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.4.* (phosphoric diester hydrolase) inhibitors", "phosphodiesterase inhibitor", "phosphodiesterase inhibitors", "phosphoric diester hydrolase (EC 3.1.4.*) inhibitor", "phosphoric diester hydrolase (EC 3.1.4.*) inhibitors", "phosphoric diester hydrolase inhibitor", "phosphoric diester hydrolase inhibitors" ; oboInOwl:id "CHEBI:50218" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.1.4.* (phosphoric diester hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76760 . obo:CHEBI_50266 obo:IAO_0000115 "A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug." ; oboInOwl:hasDbXref "PMID:23993918", "PMID:23998799", "PMID:24329110", "PMID:24628402", "PMID:24709544", "PMID:25144792", "PMID:25157234", "PMID:25269430", "PMID:25391982", "PMID:25591121", "PMID:25620096", "PMID:25795057", "PMID:26028253", "PMID:26184144", "PMID:28070577", "PMID:28215138", "PMID:28219047", "PMID:28259775", "PMID:28319647", "PMID:28329729", "PMID:28334528", "Wikipedia:Prodrug" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Prodrugs" ; oboInOwl:id "CHEBI:50266" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "prodrug" ; rdfs:subClassOf obo:CHEBI_136859, obo:CHEBI_23888 . obo:CHEBI_50267 obo:IAO_0000115 "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chemoprotectant", "chemoprotectants", "chemoprotective agent", "chemoprotective agents", "protective agents" ; oboInOwl:id "CHEBI:50267" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "protective agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_50297 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical nucleotide residues" ; oboInOwl:id "CHEBI:50297" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "canonical nucleotide residue" ; rdfs:subClassOf obo:CHEBI_50319 . obo:CHEBI_50298 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical deoxyribonucleotide residues" ; oboInOwl:id "CHEBI:50298" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "canonical deoxyribonucleotide residue" ; rdfs:subClassOf obo:CHEBI_50297 . obo:CHEBI_50299 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical ribonucleotide residues" ; oboInOwl:id "CHEBI:50299" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "canonical ribonucleotide residue" ; rdfs:subClassOf obo:CHEBI_50297 . obo:CHEBI_50312 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:50312" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "onium compound" ; rdfs:subClassOf obo:CHEBI_37577 . obo:CHEBI_50313 obo:IAO_0000115 "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." ; oboInOwl:hasExactSynonym "onium cations" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "onium cations", "onium ion", "onium ions" ; oboInOwl:id "CHEBI:50313" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "onium cation" ; rdfs:subClassOf obo:CHEBI_50312 . obo:CHEBI_50314 chebi:charge "+1" ; chebi:formula "FH2" ; chebi:inchi "InChI=1S/FH2/h1H2/q+1" ; chebi:inchikey "YNESUKSMQODWNS-UHFFFAOYSA-N" ; chebi:mass "21.01428" ; chebi:monoisotopicmass "21.01350" ; chebi:smiles "[H][F+][H]" ; oboInOwl:hasExactSynonym "fluoranium", "fluoronium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2F(+)", "[FH2](+)" ; oboInOwl:id "CHEBI:50314" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluoronium" ; rdfs:subClassOf obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29228 ] . obo:CHEBI_50315 chebi:charge "+1" ; chebi:formula "ClH2" ; chebi:inchi "InChI=1S/ClH2/h1H2/q+1" ; chebi:inchikey "IGJWHVUMEJASKV-UHFFFAOYSA-N" ; chebi:mass "37.46858" ; chebi:monoisotopicmass "36.98395" ; chebi:smiles "[H][Cl+][H]" ; oboInOwl:hasDbXref "Gmelin:331" ; oboInOwl:hasExactSynonym "chloranium", "chloronium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2Cl(+)", "[ClH2](+)" ; oboInOwl:id "CHEBI:50315" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chloronium" ; rdfs:subClassOf obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17883 ] . obo:CHEBI_50316 chebi:charge "+1" ; chebi:formula "BrH2" ; chebi:inchi "InChI=1S/BrH2/h1H2/q+1" ; chebi:inchikey "IWNNBBVLEFUBNE-UHFFFAOYSA-N" ; chebi:mass "81.91988" ; chebi:monoisotopicmass "80.93344" ; chebi:smiles "[H][Br+][H]" ; oboInOwl:hasDbXref "Gmelin:719134" ; oboInOwl:hasExactSynonym "bromanium", "bromonium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2Br(+)", "[BrH2](+)" ; oboInOwl:id "CHEBI:50316" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bromonium" ; rdfs:subClassOf obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_47266 ] . obo:CHEBI_50317 chebi:charge "+1" ; chebi:formula "H2I" ; chebi:inchi "InChI=1S/H2I/h1H2/q+1" ; chebi:inchikey "MGFYSGNNHQQTJW-UHFFFAOYSA-N" ; chebi:mass "128.92035" ; chebi:monoisotopicmass "128.91957" ; chebi:smiles "[H][I+][H]" ; oboInOwl:hasDbXref "Gmelin:1425841" ; oboInOwl:hasExactSynonym "iodanium", "iodonium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2I(+)", "[IH2](+)" ; oboInOwl:id "CHEBI:50317" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "iodonium" ; rdfs:subClassOf obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_43451 ] . obo:CHEBI_50319 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleotide residues" ; oboInOwl:id "CHEBI:50319" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleotide residue" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_50320 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleoside residues" ; oboInOwl:id "CHEBI:50320" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside residue" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_50325 obo:IAO_0000115 "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical amino-acid side-chain", "canonical amino-acid side-chains", "proteinogenic amino-acid side-chain", "proteinogenic amino-acid side-chain groups", "proteinogenic amino-acid side-chains" ; oboInOwl:id "CHEBI:50325" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "proteinogenic amino-acid side-chain group" ; rdfs:subClassOf obo:CHEBI_33249 . obo:CHEBI_50326 chebi:charge "0" ; chebi:formula "CH3S" ; chebi:mass "47.10052" ; chebi:monoisotopicmass "46.99555" ; chebi:smiles "SC*" ; oboInOwl:hasExactSynonym "sulfanylmethyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-CH2-SH", "HS-CH2-", "cysteine side-chain" ; oboInOwl:id "CHEBI:50326" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfanylmethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:CHEBI_50339 chebi:charge "0" ; chebi:formula "C4H10N" ; chebi:mass "72.12894" ; chebi:monoisotopicmass "72.08132" ; chebi:smiles "NCCCC*" ; oboInOwl:hasExactSynonym "4-aminobutyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "lysine side-chain" ; oboInOwl:id "CHEBI:50339" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "4-aminobutyl group" ; rdfs:subClassOf obo:CHEBI_50325, [ a owl:Restriction ; owl:onProperty chebi2:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_43799 ] . obo:CHEBI_50344 obo:IAO_0000115 "Any of the macrolides obtained as fermentation products from the bacterium Streptomyces avermitilis and consisting of a 16-membered macrocyclic backbone that is fused both benzofuran and spiroketal functions and contains a disaccharide substituent. They have significant anthelmintic and insecticidal properties." ; oboInOwl:hasDbXref "PMID:22039784", "PMID:22039799", "PMID:22542398", "PMID:23165468", "PMID:8688633", "Wikipedia:Avermectin" ; oboInOwl:hasExactSynonym "avermectin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "avermectins" ; oboInOwl:id "CHEBI:50344" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "avermectin" ; rdfs:subClassOf obo:CHEBI_25106, obo:CHEBI_59779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76969 ] . obo:CHEBI_50356 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic iodide salts" ; oboInOwl:id "CHEBI:50356" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic iodide salt" ; rdfs:subClassOf obo:CHEBI_24858, obo:CHEBI_51069 . obo:CHEBI_50491 obo:IAO_0000115 "A group derived from a haloalkane by removal of a hydrogen atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "haloalkyl groups" ; oboInOwl:id "CHEBI:50491" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "haloalkyl group" ; rdfs:subClassOf obo:CHEBI_33249 . obo:CHEBI_50511 obo:IAO_0000115 "Compounds containing a bipyridine group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bipyridyls" ; oboInOwl:id "CHEBI:50511" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bipyridines" ; rdfs:subClassOf obo:CHEBI_36820, obo:CHEBI_38101, obo:CHEBI_64459 . obo:CHEBI_50514 obo:IAO_0000115 "Drug used to cause constriction of the blood vessels." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:50514" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "vasoconstrictor agent" ; rdfs:subClassOf obo:CHEBI_35554 . obo:CHEBI_50523 obo:IAO_0000115 "A gamma-lactone that consists of a 2-furanone skeleton and its substituted derivatives." ; chebi:charge "0" ; chebi:formula "C4H4O2" ; chebi:mass "84.074" ; chebi:monoisotopicmass "84.02113" ; oboInOwl:hasAlternativeId "CHEBI:22960", "CHEBI:38121" ; oboInOwl:hasDbXref "Wikipedia:Butenolide" ; oboInOwl:hasExactSynonym "furan-2-one" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-furanone", "butenolides" ; oboInOwl:id "CHEBI:50523" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "butenolide" ; rdfs:subClassOf obo:CHEBI_24129, obo:CHEBI_37581 . obo:CHEBI_50584 obo:IAO_0000115 "An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position." ; oboInOwl:hasAlternativeId "CHEBI:22937", "CHEBI:50581" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkyl alcohols", "hydroxyalkane", "hydroxyalkanes" ; oboInOwl:id "CHEBI:50584" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alkyl alcohol" ; rdfs:subClassOf obo:CHEBI_2571 . obo:CHEBI_50733 obo:IAO_0000115 "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Dietary Supplement", "Food Supplementation", "Nutritional supplement" ; oboInOwl:id "CHEBI:50733" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nutraceutical" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_50795 obo:IAO_0000115 "A nanometre sized object." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nanoestructura" ; oboInOwl:id "CHEBI:50795" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nanostructure" ; rdfs:subClassOf obo:CHEBI_36357 . obo:CHEBI_50803 obo:IAO_0000115 "A nanosized spherical or capsule-shaped structure." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NP", "Nanoteilchen", "nanoparticles", "nanoparticula", "nanoparticule" ; oboInOwl:id "CHEBI:50803" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nanoparticle" ; rdfs:subClassOf obo:CHEBI_50795 . obo:CHEBI_50826 obo:IAO_0000115 "A nanoparticle consisting of silver atoms." ; chebi:charge "0" ; chebi:formula "Ag" ; chebi:mass "107.868" ; chebi:monoisotopicmass "106.90510" ; oboInOwl:hasDbXref "PMID:22128035", "PMID:22148238", "Wikipedia:Silver_nanoparticles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ag nanoparticle", "Ag nanoparticles", "AgNP", "silver nanoparticles" ; oboInOwl:id "CHEBI:50826" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "silver nanoparticle" ; rdfs:subClassOf obo:CHEBI_33966, obo:CHEBI_52855 . obo:CHEBI_50846 obo:IAO_0000115 "Biologically active substance whose activity affects or plays a role in the functioning of the immune system." ; oboInOwl:hasDbXref "Wikipedia:Immunotherapy" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Biomodulator", "Immune factor", "Immunologic factor", "Immunological factor", "immunomodulators" ; oboInOwl:id "CHEBI:50846" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "immunomodulator" ; rdfs:subClassOf obo:CHEBI_23888, obo:CHEBI_24432 . obo:CHEBI_50847 obo:IAO_0000115 "A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity." ; oboInOwl:hasDbXref "Wikipedia:Immunologic_adjuvant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Immunoactivator", "Immunoadjuvant", "Immunologic adjuvant", "Immunopotentiator", "Immunostimulant" ; oboInOwl:id "CHEBI:50847" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "immunological adjuvant" ; rdfs:subClassOf obo:CHEBI_50846, obo:CHEBI_60809 . obo:CHEBI_50857 obo:IAO_0000115 "A drug used to treat allergic reactions." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-allergic agents", "anti-allergic drug", "anti-allergic drugs" ; oboInOwl:id "CHEBI:50857" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anti-allergic agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_50860 obo:IAO_0000115 "Any molecular entity that contains carbon." ; oboInOwl:hasAlternativeId "CHEBI:25700", "CHEBI:33244" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic compounds", "organic entity", "organic molecular entities" ; oboInOwl:id "CHEBI:50860" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic molecular entity" ; rdfs:subClassOf obo:CHEBI_33582, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_27594 ] . obo:CHEBI_50893 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "azaarenes" ; oboInOwl:id "CHEBI:50893" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "azaarene" ; rdfs:subClassOf obo:CHEBI_33833, obo:CHEBI_38101 . obo:CHEBI_50902 obo:IAO_0000115 "A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells." ; oboInOwl:hasDbXref "Wikipedia:Genotoxicity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "genotoxic agent", "genotoxic agents", "genotoxins" ; oboInOwl:id "CHEBI:50902" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "genotoxin" ; rdfs:subClassOf obo:CHEBI_52209 . obo:CHEBI_50903 obo:IAO_0000115 "A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agente carcinogeno", "cancerigene", "cancerogene", "carcinogen", "carcinogene", "carcinogenic agents", "carcinogeno", "carcinogens" ; oboInOwl:id "CHEBI:50903" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carcinogenic agent" ; rdfs:subClassOf obo:CHEBI_52209 . obo:CHEBI_50904 obo:IAO_0000115 "A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy." ; oboInOwl:hasDbXref "Wikipedia:Allergen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alergeno", "allergene", "allergenic agent" ; oboInOwl:id "CHEBI:50904" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "allergen" ; rdfs:subClassOf obo:CHEBI_52209 . obo:CHEBI_50905 obo:IAO_0000115 "A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agent teratogene", "teratogen", "teratogeno" ; oboInOwl:id "CHEBI:50905" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "teratogenic agent" ; rdfs:subClassOf obo:CHEBI_52209 . obo:CHEBI_50906 obo:IAO_0000115 "A role is particular behaviour which a material entity may exhibit." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:50906" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "role" ; rdfs:subClassOf obo:BFO_0000023 . obo:CHEBI_50910 obo:IAO_0000115 "A poison that interferes with the functions of the nervous system." ; oboInOwl:hasAlternativeId "CHEBI:50911" ; oboInOwl:hasDbXref "Wikipedia:Neurotoxin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agente neurotoxico", "nerve poison", "nerve poisons", "neurotoxic agent", "neurotoxic agents", "neurotoxicant", "neurotoxins" ; oboInOwl:id "CHEBI:50910" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "neurotoxin" ; rdfs:subClassOf obo:CHEBI_52209, obo:CHEBI_64909 . obo:CHEBI_50925 obo:IAO_0000115 "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine." ; oboInOwl:hasAlternativeId "CHEBI:75764" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "A-kinase inhibitor", "A-kinase inhibitors", "AP50 kinase inhibitor", "AP50 kinase inhibitors", "ATP-protein transphosphorylase inhibitor", "ATP-protein transphosphorylase inhibitors", "ATP:protein phosphotransferase (non-specific) inhibitor", "ATP:protein phosphotransferase (non-specific) inhibitors", "BR serine/threonine-protein kinase 2 inhibitor", "BR serine/threonine-protein kinase 2 inhibitors", "CK-2 inhibitor", "CK-2 inhibitors", "CKI inhibitor", "CKI inhibitors", "CKII inhibitor", "CKII inhibitors", "EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitors", "EC 2.7.11.1 inhibitor", "EC 2.7.11.1 inhibitors", "HIPK2 inhibitor", "HIPK2 inhibitors", "Hpr kinase inhibitor", "Hpr kinase inhibitors", "M phase-specific cdc2 kinase inhibitor", "M phase-specific cdc2 kinase inhibitors", "MKNK2 inhibitor", "MKNK2 inhibitors", "PAK-1 inhibitor", "PAK-1 inhibitors", "PAK1 inhibitor", "PAK1 inhibitors", "PKA inhibitor", "PKA inhibitors", "Prp4 protein kinase inhibitor", "Prp4 protein kinase inhibitors", "Raf kinase inhibitor", "Raf kinase inhibitors", "Raf-1 inhibitor", "Raf-1 inhibitors", "STK32 inhibitor", "STK32 inhibitors", "T-antigen kinase inhibitor", "T-antigen kinase inhibitors", "WEE1Hu inhibitor", "WEE1Hu inhibitors", "Wee 1-like kinase inhibitor", "Wee 1-like kinase inhibitors", "Wee-kinase inhibitor", "Wee-kinase inhibitors", "betaIIPKC inhibitor", "betaIIPKC inhibitors", "cAMP-dependent protein kinase A inhibitor", "cAMP-dependent protein kinase A inhibitors", "cAMP-dependent protein kinase inhibitor", "cAMP-dependent protein kinase inhibitors", "cGMP-dependent protein kinase inhibitor", "cGMP-dependent protein kinase inhibitors", "calcium-dependent protein kinase C inhibitor", "calcium-dependent protein kinase C inhibitors", "calcium/phospholipid-dependent protein kinase inhibitor", "calcium/phospholipid-dependent protein kinase inhibitors", "casein kinase (phosphorylating) inhibitor", "casein kinase (phosphorylating) inhibitors", "casein kinase 2 inhibitor", "casein kinase 2 inhibitors", "casein kinase I inhibitor", "casein kinase I inhibitors", "casein kinase II inhibitor", "casein kinase II inhibitors", "casein kinase inhibitor", "casein kinase inhibitors", "cyclic AMP-dependent protein kinase A inhibitor", "cyclic AMP-dependent protein kinase A inhibitors", "cyclic AMP-dependent protein kinase inhibitor", "cyclic AMP-dependent protein kinase inhibitors", "cyclic monophosphate-dependent protein kinase inhibitor", "cyclic monophosphate-dependent protein kinase inhibitors", "cyclic nucleotide-dependent protein kinase inhibitor", "cyclic nucleotide-dependent protein kinase inhibitors", "cyclin-dependent kinase inhibitor", "cyclin-dependent kinase inhibitors", "dsk1 inhibitor", "dsk1 inhibitors", "epsilon PKC inhibitor", "epsilon PKC inhibitors", "glycogen synthase a kinase inhibitor", "glycogen synthase a kinase inhibitors", "glycogen synthase kinase inhibitor", "glycogen synthase kinase inhibitors", "hydroxyalkyl-protein kinase inhibitor", "hydroxyalkyl-protein kinase inhibitors", "mitogen-activated S6 kinase inhibitor", "mitogen-activated S6 kinase inhibitors", "non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitor", "non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitors", "non-specific serine/threonine protein kinase inhibitor", "non-specific serine/threonine protein kinase inhibitors", "p21 activated kinase-1 inhibitor", "p21 activated kinase-1 inhibitors", "p82 kinase inhibitor", "p82 kinase inhibitors", "phosphorylase b kinase kinase inhibitor", "phosphorylase b kinase kinase inhibitors", "protein glutamyl kinase inhibitor", "protein glutamyl kinase inhibitors", "protein kinase (phosphorylating) inhibitor", "protein kinase (phosphorylating) inhibitors", "protein kinase A inhibitor", "protein kinase A inhibitors", "protein kinase CK2 inhibitor", "protein kinase CK2 inhibitors", "protein kinase p58 inhibitor", "protein kinase p58 inhibitors", "protein phosphokinase inhibitor", "protein phosphokinase inhibitors", "protein serine kinase inhibitor", "protein serine kinase inhibitors", "protein serine-threonine kinase inhibitor", "protein serine-threonine kinase inhibitors", "protein-aspartyl kinase inhibitor", "protein-aspartyl kinase inhibitors", "protein-cysteine kinase inhibitor", "protein-cysteine kinase inhibitors", "protein-serine kinase inhibitor", "protein-serine kinase inhibitors", "protein-serine/threonine kinase inhibitors", "ribosomal S6 protein kinase inhibitor", "ribosomal S6 protein kinase inhibitors", "ribosomal protein S6 kinase II inhibitor", "ribosomal protein S6 kinase II inhibitors", "serine kinase inhibitor", "serine kinase inhibitors", "serine protein kinase inhibitor", "serine protein kinase inhibitors", "serine(threonine) protein kinase inhibitor", "serine(threonine) protein kinase inhibitors", "serine-specific protein kinase inhibitor", "serine-specific protein kinase inhibitors", "serine/threonine protein kinase inhibitor", "serine/threonine protein kinase inhibitors", "threonine-specific protein kinase inhibitor", "threonine-specific protein kinase inhibitors", "twitchin kinase inhibitor", "twitchin kinase inhibitors", "type-2 casein kinase inhibitor", "type-2 casein kinase inhibitors" ; oboInOwl:id "CHEBI:50925" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76812 . obo:CHEBI_50949 obo:IAO_0000115 "A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent." ; oboInOwl:hasDbXref "Wikipedia:Selective_serotonin_reuptake_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SSRI", "serotonin reuptake inhibitor" ; oboInOwl:id "CHEBI:50949" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "serotonin uptake inhibitor" ; rdfs:subClassOf obo:CHEBI_48278 . obo:CHEBI_50994 obo:IAO_0000115 "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "primary amino compounds" ; oboInOwl:id "CHEBI:50994" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "primary amino compound" ; rdfs:subClassOf obo:CHEBI_50047, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_65296 ] . obo:CHEBI_50995 obo:IAO_0000115 "A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "secondary amino compounds" ; oboInOwl:id "CHEBI:50995" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "secondary amino compound" ; rdfs:subClassOf obo:CHEBI_50047 . obo:CHEBI_50996 obo:IAO_0000115 "A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tertiary amino compounds" ; oboInOwl:id "CHEBI:50996" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tertiary amino compound" ; rdfs:subClassOf obo:CHEBI_50047, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_137982 ] . obo:CHEBI_51026 obo:IAO_0000115 "A cyclic compound containing nine or more atoms as part of the cyclic system." ; oboInOwl:hasDbXref "Wikipedia:Macrocycle" ; oboInOwl:hasExactSynonym "macrocycle" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Makrocyclen", "Makrozyklen", "macrocycles", "makrocyclische Verbindungen", "makrozyklische Verbindungen" ; oboInOwl:id "CHEBI:51026" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "macrocycle" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_51061 obo:IAO_0000115 "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hormone receptor modulators" ; oboInOwl:id "CHEBI:51061" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hormone receptor modulator" ; rdfs:subClassOf obo:CHEBI_90710 . obo:CHEBI_51069 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic halide salts" ; oboInOwl:id "CHEBI:51069" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic halide salt" ; rdfs:subClassOf obo:CHEBI_24868 . obo:CHEBI_51074 obo:IAO_0000115 "A colchicine that has (R)-configuration." ; chebi:charge "0" ; chebi:formula "C22H25NO6" ; chebi:inchi "InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m1/s1" ; chebi:inchikey "IAKHMKGGTNLKSZ-MRXNPFEDSA-N" ; chebi:mass "399.43704" ; chebi:monoisotopicmass "399.16819" ; chebi:smiles "COc1cc2CC[C@@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC" ; oboInOwl:hasDbXref "Beilstein:3226657", "CAS:75520-89-7", "Chemspider:48121", "PMID:28959419", "PMID:7265112" ; oboInOwl:hasExactSynonym "N-[(7R)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-colchicine", "(R)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide" ; oboInOwl:id "CHEBI:51074" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(R)-colchicine" ; rdfs:subClassOf obo:CHEBI_23359, [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_27882 ] . obo:CHEBI_51086 obo:IAO_0000115 "A role played by the molecular entity or part thereof within a chemical context." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51086" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chemical role" ; rdfs:subClassOf obo:BFO_0000023, obo:CHEBI_50906 . obo:CHEBI_51137 obo:IAO_0000115 "A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere." ; chebi:charge "0" ; chebi:formula "C18H20N2" ; chebi:inchi "InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3" ; chebi:inchikey "UEQUQVLFIPOEMF-UHFFFAOYSA-N" ; chebi:mass "264.36480" ; chebi:monoisotopicmass "264.16265" ; chebi:smiles "CN1CCN2C(C1)c1ccccc1Cc1ccccc21" ; oboInOwl:hasDbXref "Beilstein:755346", "CAS:24219-97-4", "DrugBank:DB06148", "Drug_Central:1796", "LINCS:LSM-1374", "PMID:18033297", "PMID:20825390", "Patent:NL6603256", "Patent:US3534041", "Wikipedia:Mianserin" ; oboInOwl:hasExactSynonym "2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine", "mianserin", "mianserina", "mianserine", "mianserinum" ; oboInOwl:id "CHEBI:51137" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mianserin" ; rdfs:subClassOf obo:CHEBI_47804, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35640 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35678 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35717 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37890 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37955 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48279 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76779 ] . obo:CHEBI_51143 oboInOwl:hasAlternativeId "CHEBI:25556", "CHEBI:7594" ; oboInOwl:hasDbXref "KEGG:C06061" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Nitrogenous compounds", "nitrogen compounds", "nitrogen molecular entities" ; oboInOwl:id "CHEBI:51143" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nitrogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_25555 ] . obo:CHEBI_51151 obo:IAO_0000115 "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dipolar compounds" ; oboInOwl:id "CHEBI:51151" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dipolar compound" ; rdfs:subClassOf obo:CHEBI_72695 . obo:CHEBI_5118 obo:IAO_0000115 "A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder." ; chebi:charge "0" ; chebi:formula "C17H18F3NO" ; chebi:mass "309.32610" ; chebi:monoisotopicmass "309.13405" ; oboInOwl:hasDbXref "Beilstein:39914106", "CAS:54910-89-3", "DrugBank:DB00472", "HMDB:HMDB0014615", "KEGG:D00326", "PMID:19144769", "PMID:22903652", "PMID:22923967", "PMID:23885544", "PMID:24184049", "PMID:24399719", "PMID:24464553", "PMID:24997906", "PMID:25448156", "PMID:25639887", "PMID:25671301", "PMID:8694321", "Patent:DE2500110", "Patent:US4314081", "Reaxys:3991406", "Wikipedia:Fluoxetine" ; oboInOwl:hasExactSynonym "rac-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine", "(+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine", "Prozac", "fluoxetina", "fluoxetine", "fluoxetinum" ; oboInOwl:id "CHEBI:5118" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fluoxetine" ; rdfs:subClassOf obo:CHEBI_60911, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_86991 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_86992 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35480 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50949 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_88188 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_36810 ] . obo:CHEBI_51277 obo:IAO_0000115 "A compound of general formula RC(=O)SR'. Compare with thionoester, RC(=S)OR'." ; chebi:charge "0" ; chebi:formula "COSR2" ; chebi:mass "60.07500" ; chebi:monoisotopicmass "59.96699" ; chebi:smiles "[*]C(=O)S[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "thio ester", "thioesters", "thiol ester" ; oboInOwl:id "CHEBI:51277" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "thioester" ; rdfs:subClassOf obo:CHEBI_26959, obo:CHEBI_36586 . obo:CHEBI_51280 chebi:charge "0" ; chebi:formula "C3H6OS" ; chebi:inchi "InChI=1S/C3H6OS/c1-3(4)5-2/h1-2H3" ; chebi:inchikey "OATSQCXMYKYFQO-UHFFFAOYSA-N" ; chebi:mass "90.14514" ; chebi:monoisotopicmass "90.01394" ; chebi:smiles "CSC(C)=O" ; oboInOwl:hasAlternativeId "CHEBI:38533", "CHEBI:51279" ; oboInOwl:hasDbXref "Beilstein:1736664", "CAS:1534-08-3", "Gmelin:1316927" ; oboInOwl:hasExactSynonym "S-methyl ethanethioate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3C(O)SCH3", "ethanethioic acid, S-methyl ester", "methanethiol acetate", "methyl ethanethioate", "methyl thioacetate", "methylthioacetate", "thioacetic acid S-methyl ester" ; oboInOwl:id "CHEBI:51280" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "S-methyl thioacetate" ; rdfs:subClassOf obo:CHEBI_51277, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16555 ] . obo:CHEBI_51323 obo:IAO_0000115 "An alkaloid based on a cinchonan skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cinchona alkaloids" ; oboInOwl:id "CHEBI:51323" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cinchona alkaloid" ; rdfs:subClassOf obo:CHEBI_26509 . obo:CHEBI_51371 obo:IAO_0000115 "A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "muscle relaxants" ; oboInOwl:id "CHEBI:51371" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "muscle relaxant" ; rdfs:subClassOf obo:CHEBI_51372 . obo:CHEBI_51372 obo:IAO_0000115 "A drug used for its actions on skeletal muscle." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51372" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "neuromuscular agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_51373 obo:IAO_0000115 "A drug that binds to and activates gamma-aminobutyric acid receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "GABA agonists", "GABA receptor agonist", "GABA receptor agonists", "gamma-aminobutyric acid receptor agonist", "gamma-aminobutyric acid receptor agonists" ; oboInOwl:id "CHEBI:51373" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "GABA agonist" ; rdfs:subClassOf obo:CHEBI_51374 . obo:CHEBI_51374 obo:IAO_0000115 "A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51374" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "GABA agent" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_51422 obo:IAO_0000115 "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organodiyl groups" ; oboInOwl:id "CHEBI:51422" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organodiyl group" ; rdfs:subClassOf obo:CHEBI_51446 . obo:CHEBI_51446 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51446" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "organic divalent group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_51447 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51447" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "organic univalent group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_51689 obo:IAO_0000115 "An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position." ; chebi:charge "0" ; chebi:formula "C3OR4" ; chebi:mass "52.03150" ; chebi:monoisotopicmass "51.99491" ; chebi:smiles "[*]\\C([*])=C(\\[*])C([*])=O" ; oboInOwl:hasDbXref "Wikipedia:Enone" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "enones" ; oboInOwl:id "CHEBI:51689" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "enone" ; rdfs:subClassOf obo:CHEBI_51721, obo:CHEBI_78840 . obo:CHEBI_51702 obo:IAO_0000115 "An alpha,beta-unsaturated carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position." ; chebi:charge "0" ; chebi:formula "C3O2R4" ; chebi:mass "68.03090" ; chebi:monoisotopicmass "67.98983" ; chebi:smiles "[*]\\C([*])=C(\\[*])C(=O)O[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "enoate", "enoate esters", "enoates" ; oboInOwl:id "CHEBI:51702" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "enoate ester" ; rdfs:subClassOf obo:CHEBI_51737, obo:CHEBI_78840 . obo:CHEBI_51721 obo:IAO_0000115 "A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha,beta-unsaturated ketones" ; oboInOwl:id "CHEBI:51721" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha,beta-unsaturated ketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_51737 obo:IAO_0000115 "A carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) or R(1)C#C-C(=O)OR(2) (R(2) =/= H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha,beta-unsaturated carboxylic esters" ; oboInOwl:id "CHEBI:51737" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha,beta-unsaturated carboxylic ester" ; rdfs:subClassOf obo:CHEBI_33308 . obo:CHEBI_51867 obo:IAO_0000115 "A ketone of formula RC(=O)CH3 (R =/= H)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methyl ketones" ; oboInOwl:id "CHEBI:51867" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methyl ketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_51869 obo:IAO_0000115 "A diketone that has its two ketone functionalities on adjacent atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-diketones" ; oboInOwl:id "CHEBI:51869" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-diketone" ; rdfs:subClassOf obo:CHEBI_46640 . obo:CHEBI_51958 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic polycyclic compounds" ; oboInOwl:id "CHEBI:51958" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic polycyclic compound" ; rdfs:subClassOf obo:CHEBI_33635, obo:CHEBI_33832 . obo:CHEBI_51959 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic tricyclic compounds" ; oboInOwl:id "CHEBI:51959" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic tricyclic compound" ; rdfs:subClassOf obo:CHEBI_51958 . obo:CHEBI_52090 obo:IAO_0000115 "An organic anion that is the conjugate base of methanol." ; chebi:charge "-1" ; chebi:formula "CH3O" ; chebi:inchi "InChI=1S/CH3O/c1-2/h1H3/q-1" ; chebi:inchikey "NBTOZLQBSIZIKS-UHFFFAOYSA-N" ; chebi:mass "31.03390" ; chebi:monoisotopicmass "31.01894" ; chebi:smiles "C[O-]" ; oboInOwl:hasDbXref "Reaxys:1839368" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methoxide ion" ; oboInOwl:id "CHEBI:52090" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methoxide" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17790 ] . obo:CHEBI_52092 obo:IAO_0000115 "An organic anion that is the conjugate base of ethanol." ; chebi:charge "-1" ; chebi:formula "C2H5O" ; chebi:inchi "InChI=1S/C2H5O/c1-2-3/h2H2,1H3/q-1" ; chebi:inchikey "HHFAWKCIHAUFRX-UHFFFAOYSA-N" ; chebi:mass "45.06050" ; chebi:monoisotopicmass "45.03459" ; chebi:smiles "CC[O-]" ; oboInOwl:hasDbXref "Beilstein:1839415", "Reaxys:1839415" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ethoxy anion" ; oboInOwl:id "CHEBI:52092" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ethoxide" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16236 ] . obo:CHEBI_52206 obo:IAO_0000115 "A biological role played by the molecular entity or part thereof within a biochemical context." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:52206" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "biochemical role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52208 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:52208" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "biophysical role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52209 obo:IAO_0000115 "A role played by the molecular entity or part thereof which causes the development of a pathological process." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "etiopathogenetic agent", "etiopathogenetic role" ; oboInOwl:id "CHEBI:52209" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aetiopathogenetic role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52210 obo:IAO_0000115 "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:52210" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pharmacological role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52211 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:52211" ; oboInOwl:inSubset chebi6:_STAR ; a owl:Class ; rdfs:label "physiological role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52217 obo:IAO_0000115 "Any substance introduced into a living organism with therapeutic or diagnostic purpose." ; oboInOwl:hasAlternativeId "CHEBI:33293", "CHEBI:33294" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "farmaco", "medicament", "pharmaceuticals" ; oboInOwl:id "CHEBI:52217" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pharmaceutical" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_52290 obo:IAO_0000115 "A chemical substance that encourages a cell to commence cell division, triggering mitosis." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mitogens" ; oboInOwl:id "CHEBI:52290" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mitogen" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52395 obo:IAO_0000115 "A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxyketones" ; oboInOwl:id "CHEBI:52395" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxyketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_52396 obo:IAO_0000115 "An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-oxyketones" ; oboInOwl:id "CHEBI:52396" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-oxyketone" ; rdfs:subClassOf obo:CHEBI_52395 . obo:CHEBI_52557 obo:IAO_0000115 "A diterpenoid with a tetracyclic skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tetracyclic diterpenoids" ; oboInOwl:id "CHEBI:52557" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tetracyclic diterpenoid" ; rdfs:subClassOf obo:CHEBI_23849 . obo:CHEBI_52837 oboInOwl:hasExactSynonym "quinolinium ion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "quinolinium ions" ; oboInOwl:id "CHEBI:52837" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "quinolinium ion" ; rdfs:subClassOf obo:CHEBI_25697 . obo:CHEBI_52845 obo:IAO_0000115 "An organic group that consists of a closed ring. It may be a substituent or a skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic organic groups" ; oboInOwl:id "CHEBI:52845" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic organic group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_52855 obo:IAO_0000115 "A nanoparticle that contains no carbon." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic nanoparticles" ; oboInOwl:id "CHEBI:52855" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "inorganic nanoparticle" ; rdfs:subClassOf obo:CHEBI_50803 . obo:CHEBI_53000 obo:IAO_0000115 "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antigenic determinant", "epitope function", "epitope role" ; oboInOwl:id "CHEBI:53000" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "epitope" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_53121 obo:IAO_0000115 "An antagonist at the A2A receptor." ; oboInOwl:hasDbXref "Wikipedia:Adenosine_A2A_receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenosine A2A receptor antagonists" ; oboInOwl:id "CHEBI:53121" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adenosine A2A receptor antagonist" ; rdfs:subClassOf obo:CHEBI_71232 . obo:CHEBI_53212 obo:IAO_0000115 "Organonitrogen compounds that are derivatives of isocyanic acid; compounds containing the isocyanate functional group -N=C=O (as opposed to the cyanate group, -O-C#N)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iso-cyanates" ; oboInOwl:id "CHEBI:53212" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isocyanates" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_36963, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_29202 ] . obo:CHEBI_53309 obo:IAO_0000115 "A polymer carrying multiple negative charges." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyanion", "polyanions" ; oboInOwl:id "CHEBI:53309" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polyanionic macromolecule" ; rdfs:subClassOf obo:CHEBI_53368 . obo:CHEBI_53368 obo:IAO_0000115 "A macromolecule containing ionic groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ionic polymer", "polyionic macromolecule" ; oboInOwl:id "CHEBI:53368" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ionic macromolecule" ; rdfs:subClassOf obo:CHEBI_33839 . obo:CHEBI_5391 obo:IAO_0000115 "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence." ; chebi:charge "0" ; chebi:formula "C153H225N43O49S" ; chebi:inchi "InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1" ; chebi:inchikey "MASNOZXLGMXCHN-ZLPAWPGGSA-N" ; chebi:mass "3482.74700" ; chebi:monoisotopicmass "3480.61570" ; chebi:smiles "CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O" ; oboInOwl:hasDbXref "CAS:16941-32-5", "CAS:9007-92-5", "DrugBank:DB00040", "Drug_Central:2994", "KEGG:C01501", "KEGG:D00116", "PMID:21940356", "PMID:22014161", "PMID:22154917", "PMID:22166985", "PMID:22167521", "PMID:22214853", "PMID:22227186", "PMID:22286080", "PMID:22294753", "PMID:22318544", "PMID:22334714", "PMID:22399501", "PMID:22438981", "PMID:22454291", "Reaxys:13191924", "Wikipedia:Glucagon" ; oboInOwl:hasExactSynonym "Glucagon", "L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Glucagone", "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT", "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr", "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr", "glucagon", "glucagonum" ; oboInOwl:id "CHEBI:5391" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glucagon" ; rdfs:subClassOf obo:CHEBI_25905 . obo:CHEBI_55324 obo:IAO_0000115 "A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gastrointestinal agent", "gastrointestinal agents", "gastrointestinal drugs" ; oboInOwl:id "CHEBI:55324" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "gastrointestinal drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_55373 obo:IAO_0000115 "Oxazoles in which the N and O atoms are adjacent." ; oboInOwl:hasAlternativeId "CHEBI:46813" ; oboInOwl:hasExactSynonym "isoxazoles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2-oxazoles" ; oboInOwl:id "CHEBI:55373" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isoxazoles" ; rdfs:subClassOf obo:CHEBI_35790 . obo:CHEBI_55374 obo:IAO_0000115 "An oxazolidine containing one or more oxo groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxazolidinones" ; oboInOwl:id "CHEBI:55374" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxazolidinone" ; rdfs:subClassOf obo:CHEBI_38329 . obo:CHEBI_5615 obo:IAO_0000115 "A haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position." ; chebi:charge "0" ; chebi:formula "C2HBrClF3" ; chebi:inchi "InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H" ; chebi:inchikey "BCQZXOMGPXTTIC-UHFFFAOYSA-N" ; chebi:mass "197.38125" ; chebi:monoisotopicmass "195.89022" ; chebi:smiles "[H]C(Cl)(Br)C(F)(F)F" ; oboInOwl:hasDbXref "Beilstein:1736947", "CAS:151-67-7", "DrugBank:DB01159", "Drug_Central:1356", "Gmelin:793752", "KEGG:C07515", "KEGG:D00542", "PMID:7519986", "VSDB:1806", "Wikipedia:Halothane" ; oboInOwl:hasExactSynonym "2-bromo-2-chloro-1,1,1-trifluoroethane", "Halothane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1,1-trifluoro-2-bromo-2-chloroethane", "1,1,1-trifluoro-2-chloro-2-bromoethane", "1-bromo-1-chloro-2,2,2-trifluoroethane", "2,2,2-trifluoro-1-chloro-1-bromoethane", "2-bromo-2-chloro-1,1,1-trifluoroethane", "Fluothane", "Narcotane", "Phthorothanum", "Rhodialothan", "bromochlorotrifluoroethane" ; oboInOwl:id "CHEBI:5615" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "halothane" ; rdfs:subClassOf obo:CHEBI_24469, obo:CHEBI_36683, obo:CHEBI_37141, obo:CHEBI_37143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38870 ] . obo:CHEBI_5686 obo:IAO_0000115 "A cyclic compound having as ring members atoms of at least two different elements." ; oboInOwl:hasExactSynonym "Heterocyclic compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "compuesto heterociclico", "compuestos heterociclicos", "heterocycle", "heterocyclic compounds" ; oboInOwl:id "CHEBI:5686" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "heterocyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_57299 obo:IAO_0000115 "A ribonucleoside triphosphate oxoanion that is the trianion of adenosine 5'-triphosphate arising from deprotonation of three of the four free triphosphate OH groups." ; chebi:charge "-3" ; chebi:formula "C10H13N5O13P3" ; chebi:inchi "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/p-3/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "ZKHQWZAMYRWXGA-KQYNXXCUSA-K" ; chebi:mass "504.15720" ; chebi:monoisotopicmass "503.97392" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O" ; oboInOwl:hasDbXref "Beilstein:9535056" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:57299" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ATP(3-)" ; rdfs:subClassOf obo:CHEBI_59724, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30616 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_15422 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_237958 ] . obo:CHEBI_57867 obo:IAO_0000115 "The conjugate base of a nucleoside 5'-phosphate." ; chebi:charge "-2" ; chebi:formula "C5H7O6PR2" ; chebi:mass "194.07920" ; chebi:monoisotopicmass "193.99802" ; chebi:smiles "O[C@H]1[C@@H]([*])[C@H]([*])O[C@@H]1COP([O-])([O-])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a nucleoside 5'-phosphate", "nucleoside 5'-phosphate dianions" ; oboInOwl:id "CHEBI:57867" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-phosphate dianion" ; rdfs:subClassOf obo:CHEBI_58945, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16701 ] . obo:CHEBI_57887 obo:IAO_0000115 "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C10H13N2" ; chebi:inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1" ; chebi:inchikey "APJYDQYYACXCRM-UHFFFAOYSA-O" ; chebi:mass "161.22310" ; chebi:monoisotopicmass "161.10732" ; chebi:smiles "[NH3+]CCc1c[nH]c2ccccc12" ; oboInOwl:hasDbXref "Gmelin:533978" ; oboInOwl:hasExactSynonym "2-(1H-indol-3-yl)ethanaminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tryptamine", "tryptaminium cation", "tryptaminium(1+)" ; oboInOwl:id "CHEBI:57887" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tryptaminium" ; rdfs:subClassOf obo:CHEBI_65296, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16765 ] . obo:CHEBI_57925 obo:IAO_0000115 "A peptide anion obtained by deprotonation of both carboxy groups and protonation of the glutamyl amino group of glutathione; major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C10H16N3O6S" ; chebi:inchi "InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/p-1/t5-,6-/m0/s1" ; chebi:inchikey "RWSXRVCMGQZWBV-WDSKDSINSA-M" ; chebi:mass "306.310" ; chebi:monoisotopicmass "306.07653" ; chebi:smiles "[NH3+][C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)[O-])C(=O)[O-]" ; oboInOwl:hasDbXref "PMID:4200890", "PMID:4745654" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glutathionate", "glutathionate anion", "glutathionate ion", "glutathione" ; oboInOwl:id "CHEBI:57925" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glutathionate(1-)" ; rdfs:subClassOf obo:CHEBI_60334, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16856 ] . obo:CHEBI_57977 obo:IAO_0000115 "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3." ; chebi:charge "-2" ; chebi:formula "C33H34N4O6" ; chebi:inchi "InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/p-2/b26-13-,27-14-" ; chebi:inchikey "BPYKTIZUTYGOLE-IFADSCNNSA-L" ; chebi:mass "582.64630" ; chebi:monoisotopicmass "582.24893" ; chebi:smiles "CC1=C(C=C)\\C(NC1=O)=C\\c1[nH]c(Cc2[nH]c(\\C=C3NC(=O)C(C=C)=C/3C)c(C)c2CCC([O-])=O)c(CCC([O-])=O)c1C" ; oboInOwl:hasDbXref "Beilstein:4083310" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-1,10,19,22,23,24-hexahydro-21H-biline-8,12-dipropanoate", "bilirubin IXalpha", "bilirubin dianion" ; oboInOwl:id "CHEBI:57977" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bilirubin(2-)" ; rdfs:subClassOf obo:CHEBI_28965, obo:CHEBI_59252, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16990 ] . obo:CHEBI_58001 obo:IAO_0000115 "The conjugate acid of a primary aliphatic amine." ; chebi:charge "+1" ; chebi:formula "CH5NR" ; chebi:mass "31.05710" ; chebi:monoisotopicmass "31.04220" ; chebi:smiles "[NH3+]C[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an aliphatic amine", "primary aliphatic ammonium cation", "primary aliphatic ammonium cations", "primary aliphatic ammonium ions" ; oboInOwl:id "CHEBI:58001" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "primary aliphatic ammonium ion" ; rdfs:subClassOf obo:CHEBI_65296, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17062 ] . obo:CHEBI_58025 obo:IAO_0000115 "The conjugate acid of octopamine; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C8H12NO2" ; chebi:inchi "InChI=1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2/p+1" ; chebi:inchikey "QHGUCRYDKWKLMG-UHFFFAOYSA-O" ; chebi:mass "154.18640" ; chebi:monoisotopicmass "154.08626" ; chebi:smiles "[NH3+]CC(O)c1ccc(O)cc1" ; oboInOwl:hasExactSynonym "2-hydroxy-2-(4-hydroxyphenyl)ethanaminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-hydroxy-2-(4-hydroxyphenyl)ethan-1-aminium", "4-(2-ammonio-1-hydroxyethyl)phenol", "4-(2-azaniumyl-1-hydroxyethyl)phenol", "octopamine", "octopaminium cation", "octopaminium(1+)" ; oboInOwl:id "CHEBI:58025" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "octopaminium" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17134 ] . obo:CHEBI_58104 obo:IAO_0000115 "Trianion of nucleoside triphosphate arising from deprotonation of three of the four free triphosphate OH groups." ; chebi:charge "-3" ; chebi:formula "C5H9O13P3R" ; chebi:mass "370.039" ; chebi:monoisotopicmass "369.92560" ; chebi:smiles "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)([O-])O)(=O)[O-])(=O)[O-]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NTP trianion", "NTP(3-)", "nucleoside triphosphate trianion", "ribonucleoside triphosphate trianion", "ribonucleoside triphosphate(3-)" ; oboInOwl:id "CHEBI:58104" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-triphoshate(3-)" ; rdfs:subClassOf obo:CHEBI_59724, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_61557 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17326 ] . obo:CHEBI_58165 obo:IAO_0000115 "An organophosphate oxoanion that is the conjugate base of 3',5'-cyclic AMP arising from deprotonation of the free phosphate OH group; major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C10H11N5O6P" ; chebi:inchi "InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/p-1/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "IVOMOUWHDPKRLL-KQYNXXCUSA-M" ; chebi:mass "328.19800" ; chebi:monoisotopicmass "328.04524" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1O" ; oboInOwl:hasDbXref "PMID:7870041", "PMID:7870042", "Reaxys:3720459" ; oboInOwl:hasExactSynonym "adenosine 3',5'-phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3',5'-cyclic AMP", "3',5'-cyclic AMP anion", "adenosine 3',5'-cyclic monophosphate", "adenosine 3',5'-cyclic monophosphate anion", "adenosine 3',5'-cyclic monophosphate(1-)" ; oboInOwl:id "CHEBI:58165" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "3',5'-cyclic AMP(1-)" ; rdfs:subClassOf obo:CHEBI_58945, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17489 ] . obo:CHEBI_58464 obo:IAO_0000115 "The conjugate base of a nucleoside 3',5'-cyclic phosphate." ; chebi:charge "-1" ; chebi:formula "C5H6O5PR2" ; chebi:mass "177.07190" ; chebi:monoisotopicmass "176.99528" ; chebi:smiles "[O-]P1(=O)OC[C@H]2O[C@@H]([*])[C@H]([*])[C@@H]2O1" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a nucleoside 3',5'-cyclic phosphate", "nucleoside 3',5'-cyclic phosphate anions" ; oboInOwl:id "CHEBI:58464" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside 3',5'-cyclic phosphate anion" ; rdfs:subClassOf obo:CHEBI_58945, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_18375 ] . obo:CHEBI_58945 obo:IAO_0000115 "An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organophosphate oxoanions" ; oboInOwl:id "CHEBI:58945" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organophosphate oxoanion" ; rdfs:subClassOf obo:CHEBI_25696, obo:CHEBI_26079 . obo:CHEBI_58951 obo:IAO_0000115 "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6)." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a short-chain fatty acid", "short-chain fatty acid anions" ; oboInOwl:id "CHEBI:58951" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "short-chain fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_26666 ] . obo:CHEBI_58953 obo:IAO_0000115 "Any fatty acid anion in which there is no C-C unsaturation." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "saturated fatty acid anions" ; oboInOwl:id "CHEBI:58953" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "saturated fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868 . obo:CHEBI_58954 obo:IAO_0000115 "Any saturated fatty acid anion lacking a carbon side-chain." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "straight-chain saturated fatty acid anions" ; oboInOwl:id "CHEBI:58954" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "straight-chain saturated fatty acid anion" ; rdfs:subClassOf obo:CHEBI_58953, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_39418 ] . obo:CHEBI_58958 obo:IAO_0000115 "An organic anion of general formula RS(=O)2O(-) where R is an organyl group." ; chebi:charge "-1" ; chebi:formula "O4SR" ; chebi:mass "96.06300" ; chebi:monoisotopicmass "95.95173" ; chebi:smiles "[O-]S(=O)(=O)O[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organosulfate oxoanions" ; oboInOwl:id "CHEBI:58958" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organosulfate oxoanion" ; rdfs:subClassOf obo:CHEBI_25696, obo:CHEBI_33482, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16189 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_25704 ] . obo:CHEBI_59059 obo:IAO_0000115 "The isocyanate that is methane modified by a single isocyanato substituent." ; chebi:charge "0" ; chebi:formula "C2H3NO" ; chebi:inchi "InChI=1S/C2H3NO/c1-3-2-4/h1H3" ; chebi:inchikey "HAMGRBXTJNITHG-UHFFFAOYSA-N" ; chebi:mass "57.05130" ; chebi:monoisotopicmass "57.02146" ; chebi:smiles "CN=C=O" ; oboInOwl:hasDbXref "Beilstein:605318", "CAS:624-83-9", "DrugBank:DB04337", "Gmelin:100500", "PMID:16091349", "PMID:19494520", "PMID:24081639", "PMID:3622432", "PMID:6821040", "Reaxys:605318" ; oboInOwl:hasExactSynonym "isocyanatomethane", "methyl isocyanate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Iso-cyanatomethane", "Isocyanate de methyle", "MIC", "Methyl carbonimide", "Methyl isocyanide", "Methylcarbylamine", "isocyanatomethane" ; oboInOwl:id "CHEBI:59059" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methyl isocyanate" ; rdfs:subClassOf obo:CHEBI_53212, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50904 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_68495 ] . obo:CHEBI_59137 obo:IAO_0000115 "Cinchonan or its (8S)-epimer." ; chebi:charge "0" ; chebi:formula "C19H22N2" ; chebi:inchi "InChI=1S/C19H22N2/c1-2-14-13-21-10-8-15(14)11-17(21)12-16-7-9-20-19-6-4-3-5-18(16)19/h2-7,9,14-15,17H,1,8,10-13H2/t14-,15-,17?/m0/s1" ; chebi:inchikey "UFJOYVQIDSNLHC-GIIGEWEBSA-N" ; chebi:mass "278.39140" ; chebi:monoisotopicmass "278.17830" ; chebi:smiles "C=C[C@H]1C[N@@]2CC[C@H]1CC2Cc1ccnc2ccccc12" ; oboInOwl:hasExactSynonym "(8xi)-cinchonan" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:59137" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(8xi)-cinchonan" ; rdfs:subClassOf obo:CHEBI_26513 . obo:CHEBI_59138 obo:IAO_0000115 "The (8S)-epimer of cinchonan." ; chebi:charge "0" ; chebi:formula "C19H22N2" ; chebi:inchi "InChI=1S/C19H22N2/c1-2-14-13-21-10-8-15(14)11-17(21)12-16-7-9-20-19-6-4-3-5-18(16)19/h2-7,9,14-15,17H,1,8,10-13H2/t14-,15-,17-/m0/s1" ; chebi:inchikey "UFJOYVQIDSNLHC-ZOBUZTSGSA-N" ; chebi:mass "278.39140" ; chebi:monoisotopicmass "278.17830" ; chebi:smiles "[H][C@]1(C[C@@H]2CC[N@]1C[C@@H]2C=C)Cc1ccnc2ccccc12" ; oboInOwl:hasDbXref "Beilstein:88419" ; oboInOwl:hasExactSynonym "(8S)-cinchonan", "(8alpha)-cinchonan" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-((1S,2S,4S,5R)-5-vinyl-1-azabicyclo[2.2.2]oct-2-ylmethyl)quinoline" ; oboInOwl:id "CHEBI:59138" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(8S)-cinchonan" ; rdfs:subClassOf obo:CHEBI_59137 . obo:CHEBI_59163 obo:IAO_0000115 "A substance used as an indicator of a biological state." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "biological marker" ; oboInOwl:id "CHEBI:59163" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "biomarker" ; rdfs:subClassOf obo:CHEBI_47867 . obo:CHEBI_59202 obo:IAO_0000115 "Any fatty acid whose skeletal carbon atoms form an unbranched open chain." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "straight-chain fatty acids" ; oboInOwl:id "CHEBI:59202" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "straight-chain fatty acid" ; rdfs:subClassOf obo:CHEBI_35366, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_59203 ] . obo:CHEBI_59203 obo:IAO_0000115 "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "straight-chain FA anion", "straight-chain FA anions", "straight-chain fatty acid anions" ; oboInOwl:id "CHEBI:59203" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "straight-chain fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_59202 ] . obo:CHEBI_5924 obo:IAO_0000115 "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.4.21.* (serine endopeptidase) inhibitors", "EC 3.4.21.* inhibitor", "EC 3.4.21.* inhibitors", "inhibitor of serine endopeptidase (EC 3.4.21.*)", "inhibitor of serine endopeptidase (EC 3.4.21.*)s", "serine endopeptidase inhibitor", "serine endopeptidase inhibitors" ; oboInOwl:id "CHEBI:5924" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.4.21.* (serine endopeptidase) inhibitor" ; rdfs:subClassOf obo:CHEBI_60258 . obo:CHEBI_59252 obo:IAO_0000115 "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acyclic tetrapyrrole anion", "acyclic tetrapyrrole anions", "linear tetrapyrrole anions" ; oboInOwl:id "CHEBI:59252" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "linear tetrapyrrole anion" ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_59517 obo:IAO_0000115 "Any substance that inhibits the synthesis of DNA." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "DNA synthesis inhibitors" ; oboInOwl:id "CHEBI:59517" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "DNA synthesis inhibitor" ; rdfs:subClassOf obo:CHEBI_76932 . obo:CHEBI_59554 obo:IAO_0000115 "Any fatty acid with a chain length of between C6 and C12." ; chebi:charge "0" ; chebi:formula "CHO2R" ; chebi:mass "45.01740" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "OC([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "MCFA", "MCFAs", "medium-chain fatty acids" ; oboInOwl:id "CHEBI:59554" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "medium-chain fatty acid" ; rdfs:subClassOf obo:CHEBI_35366, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_59558 ] . obo:CHEBI_59558 obo:IAO_0000115 "A fatty acid anion resulting from the deprotonation of the carboxylic acid moiety of a medium-chain fatty acid." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "MCFA anion", "MCFA anions", "a medium chain fatty acid", "medium-chain FA anion", "medium-chain FA anions", "medium-chain fatty acid anions" ; oboInOwl:id "CHEBI:59558" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "medium-chain fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_59554 ] . obo:CHEBI_59561 obo:IAO_0000115 "An organic anion that is the conjugate base of diamino acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "diamino acid anions" ; oboInOwl:id "CHEBI:59561" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "diamino acid anion" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35987 ] . obo:CHEBI_59683 obo:IAO_0000115 "A drug, usually applied topically, that relieves pruritus (itching)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-itching drug", "anti-itching drugs", "antipruritic agent", "antipruritic agents", "antipruritic drugs" ; oboInOwl:id "CHEBI:59683" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antipruritic drug" ; rdfs:subClassOf obo:CHEBI_50177 . obo:CHEBI_59698 obo:IAO_0000115 "Compounds containing one or more phosphoric acid units." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:59698" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phosphoric acids" ; rdfs:subClassOf obo:CHEBI_33457 . obo:CHEBI_59724 obo:IAO_0000115 "An organophosphate anion resulting from deprotonation of at least one of the acidic hydroxy groups from the triphosphate moiety of a nucleoside triphosphate." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleoside triphosphate anion", "ribonucleoside triphosphate anions", "ribonucleoside triphosphate oxoanions" ; oboInOwl:id "CHEBI:59724" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ribonucleoside triphosphate oxoanion" ; rdfs:subClassOf obo:CHEBI_58945 . obo:CHEBI_59740 obo:IAO_0000115 "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleophile", "nucleophiles", "nucleophilic reagents" ; oboInOwl:id "CHEBI:59740" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleophilic reagent" ; rdfs:subClassOf obo:CHEBI_33893, obo:CHEBI_39144 . obo:CHEBI_59769 obo:IAO_0000115 "An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' =/= H). Mixed acetals have R'' and R''' groups which differ." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acetals" ; oboInOwl:id "CHEBI:59769" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "acetal" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_59777 obo:IAO_0000115 "An acetal of formula R2C(OR)2 (R =/= H) derived from a ketone by replacement of the oxo group by two hydrocarbyloxy groups. The class name 'ketals', once abandoned by IUPAC, has been reinstated as a subclass of acetals." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ketals" ; oboInOwl:id "CHEBI:59777" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ketal" ; rdfs:subClassOf obo:CHEBI_59769 . obo:CHEBI_59779 obo:IAO_0000115 "A ketal in the molecule of which the ketal carbon and one or both oxygen atoms thereon are members of a ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic ketals" ; oboInOwl:id "CHEBI:59779" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cyclic ketal" ; rdfs:subClassOf obo:CHEBI_38104, obo:CHEBI_59777 . obo:CHEBI_59806 obo:IAO_0000115 "The conjugate acid of (S)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C10H15N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/p+1/t10-/m0/s1" ; chebi:inchikey "SNICXCGAKADSCV-JTQLQIEISA-O" ; chebi:mass "163.23900" ; chebi:monoisotopicmass "163.12297" ; chebi:smiles "C[NH+]1CCC[C@H]1c1cccnc1" ; oboInOwl:hasDbXref "Gmelin:329042", "MetaCyc:NICOTINE" ; oboInOwl:hasExactSynonym "(2S)-1-methyl-2-(pyridin-3-yl)pyrrolidinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(S)-nicotine", "(S)-nicotinium cation" ; oboInOwl:id "CHEBI:59806" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(S)-nicotinium(1+)" ; rdfs:subClassOf obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17688 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_79008 ] . obo:CHEBI_59814 obo:IAO_0000115 "Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group." ; chebi:charge "-1" ; chebi:formula "C2H3NO2R" ; chebi:mass "73.051" ; chebi:monoisotopicmass "73.01638" ; chebi:smiles "[C@H](C(=O)[O-])(N)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-alpha-amino carboxylate" ; oboInOwl:id "CHEBI:59814" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-alpha-amino acid anion" ; rdfs:subClassOf obo:CHEBI_33558, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_15705 ] . obo:CHEBI_59869 obo:IAO_0000115 "Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "[NH3+][C@@H]([*])C([O-])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-alpha-amino acid zwitterions", "an L-alpha-amino acid" ; oboInOwl:id "CHEBI:59869" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-alpha-amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_78608, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_15705 ] . obo:CHEBI_59871 obo:IAO_0000115 "Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "[NH3+][C@H]([*])C([O-])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "D-alpha-amino acid zwitterions", "a D-alpha-amino acid" ; oboInOwl:id "CHEBI:59871" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-alpha-amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16733 ] . obo:CHEBI_59888 obo:IAO_0000115 "Zwitterionic form of gamma-aminobutyric acid having an anionic carboxy group and a protonated amino group." ; chebi:charge "0" ; chebi:formula "C4H9NO2" ; chebi:inchi "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" ; chebi:inchikey "BTCSSZJGUNDROE-UHFFFAOYSA-N" ; chebi:mass "103.11980" ; chebi:monoisotopicmass "103.06333" ; chebi:smiles "[NH3+]CCCC([O-])=O" ; oboInOwl:hasDbXref "Gmelin:1041559" ; oboInOwl:hasExactSynonym "4-azaniumylbutanoate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-aminobutanoate", "4-ammoniobutanoate" ; oboInOwl:id "CHEBI:59888" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "gamma-aminobutyric acid zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16865 ] . obo:CHEBI_59905 obo:IAO_0000115 "An ammonium ion that is the conjugate acid of dopamine; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C8H12NO2" ; chebi:inchi "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2/p+1" ; chebi:inchikey "VYFYYTLLBUKUHU-UHFFFAOYSA-O" ; chebi:mass "154.18640" ; chebi:monoisotopicmass "154.08626" ; chebi:smiles "[NH3+]CCc1ccc(O)c(O)c1" ; oboInOwl:hasDbXref "Gmelin:328863" ; oboInOwl:hasExactSynonym "2-(3,4-dihydroxyphenyl)ethanaminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-(3,4-dihydroxyphenyl)ethan-1-aminium", "dopamine", "dopaminium cation" ; oboInOwl:id "CHEBI:59905" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dopaminium(1+)" ; rdfs:subClassOf obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_18243 ] . obo:CHEBI_59999 obo:IAO_0000115 "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Chemische Substanz" ; oboInOwl:id "CHEBI:59999" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "chemical substance" ; rdfs:subClassOf obo:CHEBI_24431 . obo:CHEBI_60004 obo:IAO_0000115 "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Mischung" ; oboInOwl:id "CHEBI:60004" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mixture" ; rdfs:subClassOf obo:CHEBI_59999 . obo:CHEBI_60027 obo:IAO_0000115 "A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.." ; oboInOwl:hasDbXref "Wikipedia:Polymer" ; oboInOwl:hasExactSynonym "Polymer" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kunststoff" ; oboInOwl:id "CHEBI:60027" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polymer" ; rdfs:subClassOf obo:CHEBI_60004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33839 ] . obo:CHEBI_6015 chebi:charge "0" ; chebi:formula "C3H2ClF5O" ; chebi:inchi "InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H" ; chebi:inchikey "PIWKPBJCKXDKJR-UHFFFAOYSA-N" ; chebi:mass "184.49210" ; chebi:monoisotopicmass "183.97143" ; chebi:smiles "FC(F)OC(Cl)C(F)(F)F" ; oboInOwl:hasDbXref "CAS:26675-46-7", "DrugBank:DB00753", "Drug_Central:1493", "KEGG:C07518", "KEGG:D00545", "VSDB:1804", "Wikipedia:Isoflurane" ; oboInOwl:hasExactSynonym "2-chloro-2-difluoromethoxy-1,1,1-trifluoroethane", "Isoflurane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-chloro-2,2,2-trifluoroethyl difluoromethyl ether", "Aerrane", "Ethane", "Forane", "Forene", "isoflurane", "isoflurano", "isofluranum" ; oboInOwl:id "CHEBI:6015" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "isoflurane" ; rdfs:subClassOf obo:CHEBI_37143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38870 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_39832 ] . obo:CHEBI_60164 obo:IAO_0000115 "An ionic polymer is a polymer, composed of ionic macromolecules." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyionic polymer" ; oboInOwl:id "CHEBI:60164" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ionic polymer" ; rdfs:subClassOf obo:CHEBI_60027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_53368 ] . obo:CHEBI_60240 obo:IAO_0000115 "A metal cation with a valence of two." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a divalent metal cation" ; oboInOwl:id "CHEBI:60240" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "divalent metal cation" ; rdfs:subClassOf obo:CHEBI_25213, obo:CHEBI_64641 . obo:CHEBI_60242 obo:IAO_0000115 "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a monovalent cation" ; oboInOwl:id "CHEBI:60242" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monovalent inorganic cation" ; rdfs:subClassOf obo:CHEBI_36915 . obo:CHEBI_60258 obo:IAO_0000115 "A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*)." ; oboInOwl:hasAlternativeId "CHEBI:76763" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.4.* (hydrolase acting on peptide bond) inhibitor", "EC 3.4.* (hydrolase acting on peptide bonds) inhibitors", "EC 3.4.* (hydrolases acting on peptide bond) inhibitors", "EC 3.4.* (peptidase) inhibitor", "EC 3.4.* (peptidase) inhibitors", "EC 3.4.* inhibitor", "EC 3.4.* inhibitors", "inhibitor of hydrolases acting on peptide bond (EC 3.4.*)", "inhibitors of hydrolases acting on peptide bond (EC 3.4.*)", "peptidase inhibitors", "protease inhibitor", "protease inhibitors" ; oboInOwl:id "CHEBI:60258" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.4.* (hydrolases acting on peptide bond) inhibitor" ; rdfs:subClassOf obo:CHEBI_76759 . obo:CHEBI_60330 obo:IAO_0000115 "The oxime resulting from the formal condensation of 2-methyl-2-(methylsulfanyl)propanal with hydroxylamine. Addition of the oxime group to methyl isocyanate forms the final step in the synthesis of the systemic insecticide aldicarb." ; chebi:charge "0" ; chebi:formula "C5H11NOS" ; chebi:inchi "InChI=1S/C5H11NOS/c1-5(2,8-3)4-6-7/h4,7H,1-3H3" ; chebi:inchikey "ZFGMCJAXIZTVJA-UHFFFAOYSA-N" ; chebi:mass "133.21200" ; chebi:monoisotopicmass "133.05614" ; chebi:smiles "[H]C(=NO)C(C)(C)SC" ; oboInOwl:hasDbXref "Beilstein:2038299", "CAS:1646-75-9", "Patent:US3217037", "Reaxys:2038299" ; oboInOwl:hasExactSynonym "2-methyl-2-(methylsulfanyl)propanal oxime", "N-hydroxy-2-methyl-2-(methylsulfanyl)propan-1-imine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-(methylthio)-2-methylpropionaldehyde oxime", "2-(methylthio)isobutyraldehyde oxime", "2-methyl-2-(methylsulfanyl)propanaldoxime", "2-methyl-2-(methylthio)propanal oxime", "2-methyl-2-(methylthio)propionaldehyde oxime", "2-methyl-2-(methylthio)propionaldoxime", "ADO", "Temik oxime", "aldicarb oxime" ; oboInOwl:id "CHEBI:60330" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "2-methyl-2-(methylsulfanyl)propanal oxime" ; rdfs:subClassOf obo:CHEBI_82744, obo:CHEBI_86315 . obo:CHEBI_60334 obo:IAO_0000115 "An anion formed by deprotonation of at least one peptide carboxy group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "peptide anions" ; oboInOwl:id "CHEBI:60334" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "peptide anion" ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_60466 obo:IAO_0000115 "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." ; chebi:charge "0" ; chebi:formula "C2H4NO2R(C2H2NOR)n" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a peptide", "peptide zwitterions" ; oboInOwl:id "CHEBI:60466" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "peptide zwitterion" ; rdfs:subClassOf obo:CHEBI_27369, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16670 ] . obo:CHEBI_60643 obo:IAO_0000115 "Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs." ; oboInOwl:hasAlternativeId "CHEBI:60797" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-methyl-D-aspartate receptor antagonist", "N-methyl-D-aspartate receptor antagonists", "NMDA receptor antagonists", "NMDAR antagonist", "NMDAR antagonists" ; oboInOwl:id "CHEBI:60643" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "NMDA receptor antagonist" ; rdfs:subClassOf obo:CHEBI_60798 . obo:CHEBI_6078 obo:IAO_0000115 "A mixture consisting of >= 90% 22,23-dihydroavermectin B1a (R = Me) and <= 10% 22,23-dihydroavermectin B1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice." ; chebi:charge "0" ; chebi:formula "C47H71O14R", "C48H74O14.C47H72O14" ; chebi:mass "860.060" ; chebi:monoisotopicmass "859.48438" ; chebi:smiles "[H][C@@]12C\\C=C(C)\\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\\C=C\\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(CC[C@H](C)[C@]([H])(O1)[C@@H](C)C[*])O2)[C@]34O" ; oboInOwl:hasDbXref "CAS:70288-86-7", "Chemspider:7988461", "DrugBank:DB00602", "KEGG:D00804", "PMID:15078277", "PMID:18718154", "PMID:21824728", "PMID:21831526", "PMID:22039784", "PMID:22039801", "PMID:22047763", "Patent:US4199569", "Pesticides:ivermectin", "VSDB:1455", "Wikipedia:Ivermectin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ivermax", "Ivomec", "Mectizan", "Noromectin", "Privermectin", "Sklice", "Stromectol", "Vetrimec", "Zimecterin", "ivermectin", "ivermectine", "ivermectino", "ivermectinum" ; oboInOwl:id "CHEBI:6078" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ivermectin" ; rdfs:subClassOf obo:CHEBI_60004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_63941 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_63943 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24852 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35444 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35820 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_73333 ] . obo:CHEBI_60798 obo:IAO_0000115 "Any substance which inhibits the action of receptors for excitatory amino acids." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EAA receptor antagonist", "EAA receptor antagonists", "excitatory amino acid antagonists", "excitatory amino acid receptor antagonist", "excitatory amino acid receptor antagonists" ; oboInOwl:id "CHEBI:60798" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "excitatory amino acid antagonist" ; rdfs:subClassOf obo:CHEBI_48706 . obo:CHEBI_60809 obo:IAO_0000115 "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adjuvants" ; oboInOwl:id "CHEBI:60809" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adjuvant" ; rdfs:subClassOf obo:CHEBI_52217 . obo:CHEBI_60832 obo:IAO_0000115 "Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tubulin modulators" ; oboInOwl:id "CHEBI:60832" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tubulin modulator" ; rdfs:subClassOf obo:CHEBI_52210 . obo:CHEBI_60895 obo:IAO_0000115 "Any alpha-amino acid anion in which the parent amino acid has D-configuration." ; chebi:charge "-1" ; chebi:formula "C2H3NO2R" ; chebi:mass "73.051" ; chebi:monoisotopicmass "73.01638" ; chebi:smiles "[C@@H](C(=O)[O-])(N)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "D-alpha-amino acid anions", "D-alpha-amino carboxylate" ; oboInOwl:id "CHEBI:60895" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "D-alpha-amino acid anion" ; rdfs:subClassOf obo:CHEBI_33558, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16733 ] . obo:CHEBI_60911 obo:IAO_0000115 "A racemate is an equimolar mixture of a pair of enantiomers." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "melange racemique", "racemates", "racemic mixture" ; oboInOwl:id "CHEBI:60911" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "racemate" ; rdfs:subClassOf obo:CHEBI_60004 . obo:CHEBI_61115 obo:IAO_0000115 "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98)." ; oboInOwl:hasDbXref "Wikipedia:Histone_deacetylase_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.5.1.98 (histone deacetylase) inhibitors", "EC 3.5.1.98 inhibitor", "EC 3.5.1.98 inhibitors", "HDAC inhibitor", "HDAC inhibitors", "HDACi", "HDACis", "HDI", "HDIs", "histone amidohydrolase inhibitor", "histone amidohydrolase inhibitors", "histone deacetylase (EC 3.5.1.98) inhibitor", "histone deacetylase (EC 3.5.1.98) inhibitors", "histone deacetylase inhibitor", "histone deacetylase inhibitors" ; oboInOwl:id "CHEBI:61115" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.5.1.98 (histone deacetylase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76807 . obo:CHEBI_61120 obo:IAO_0000115 "Any compound that has a nucleobase as a part." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleobase-containing compound", "nucleobase-containing compounds", "nucleobase-containing molecular entities" ; oboInOwl:id "CHEBI:61120" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleobase-containing molecular entity" ; rdfs:subClassOf obo:CHEBI_33833, obo:CHEBI_51143, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_18282 ] . obo:CHEBI_61293 obo:IAO_0000115 "A nucleotide having adenine as the base." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenine nucleotide" ; oboInOwl:id "CHEBI:61293" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adenyl nucleotide" ; rdfs:subClassOf obo:CHEBI_26395 . obo:CHEBI_61296 obo:IAO_0000115 "A purine riboncleotide where adenine is the purine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenine ribonucleotide" ; oboInOwl:id "CHEBI:61296" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adenyl ribonucleotide" ; rdfs:subClassOf obo:CHEBI_26400, obo:CHEBI_61293 . obo:CHEBI_61469 obo:IAO_0000115 "A polymer, composed of polyanion macromolecules." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyanion", "polyanions" ; oboInOwl:id "CHEBI:61469" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polyanionic polymer" ; rdfs:subClassOf obo:CHEBI_60164, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_53309 ] . obo:CHEBI_61557 obo:IAO_0000115 "A ribonucleoside triphosphate oxoanion arising from global deprotonation of the triphosphate groups of any nucleoside triphosphate; major species at pH 7.3." ; chebi:charge "-4" ; chebi:formula "C5H8O13P3R" ; chebi:mass "369.031" ; chebi:monoisotopicmass "368.91778" ; chebi:smiles "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)([O-])[O-])(=O)[O-])(=O)[O-]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NTP tetraanion", "NTP(4-)", "a ribonucleoside 5'-triphosphate", "nucleoside 5'-triphosphate tetraanion", "nucleoside triphosphate(4-)" ; oboInOwl:id "CHEBI:61557" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-triphoshate(4-)" ; rdfs:subClassOf obo:CHEBI_59724, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_58104 ] . obo:CHEBI_61692 obo:IAO_0000115 "An organic heterotricyclic compound with a skeleton derived from a pyridine ring fused to an isoquinoline." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyridoisoquinolines" ; oboInOwl:id "CHEBI:61692" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pyridoisoquinoline" ; rdfs:subClassOf obo:CHEBI_26979 . obo:CHEBI_61697 obo:IAO_0000115 "Any organic molecular entity derived from a fatty acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "FA derivative", "FA derivatives", "fatty acid derivatives" ; oboInOwl:id "CHEBI:61697" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fatty acid derivative" ; rdfs:subClassOf obo:CHEBI_18059, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_35366 ] . obo:CHEBI_61951 obo:IAO_0000115 "Any substance that interacts with tubulin to inhibit polymerisation of microtubules." ; oboInOwl:hasDbXref "PMID:17099073" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "microtubule destabilising agent", "microtubule destabilising agents", "microtubule destabilising role", "microtubule destabilizing role", "microtubule-destabilising agents", "microtubule-destabilizing agent", "microtubule-destabilizing agents" ; oboInOwl:id "CHEBI:61951" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "microtubule-destabilising agent" ; rdfs:subClassOf obo:CHEBI_60832, obo:CHEBI_64911 . obo:CHEBI_62031 obo:IAO_0000115 "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "C(C([O-])=O)(*)[NH3+]" ; oboInOwl:hasDbXref "MetaCyc:Polar-amino-acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a polar amino acid" ; oboInOwl:id "CHEBI:62031" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "polar amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_26167 ] . obo:CHEBI_62081 obo:IAO_0000115 "An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens." ; chebi:charge "-1" ; chebi:formula "CH2O3SR" ; chebi:mass "94.09000" ; chebi:monoisotopicmass "93.97246" ; chebi:smiles "[H]C([H])([*])S([O-])(=O)=O" ; oboInOwl:hasDbXref "KEGG:C15521", "MetaCyc:Alkanesulfonates" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1-di-unsubstituted alkanesulfonate", "1,1-di-unsubstituted alkanesulfonates", "1,1-diunsubstituted alkanesulfonates" ; oboInOwl:id "CHEBI:62081" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "1,1-diunsubstituted alkanesulfonate" ; rdfs:subClassOf obo:CHEBI_134249, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ] . obo:CHEBI_62488 obo:IAO_0000115 "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "signal molecule", "signal molecules", "signaling molecule", "signaling molecules", "signalling molecules" ; oboInOwl:id "CHEBI:62488" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "signalling molecule" ; rdfs:subClassOf obo:CHEBI_33280 . obo:CHEBI_62643 obo:IAO_0000115 "Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1-), phosphatidate(2-), phosphatidylglycerol(1-)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anionic phospholipids", "phospholipid anion", "phospholipid anions" ; oboInOwl:id "CHEBI:62643" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anionic phospholipid" ; rdfs:subClassOf obo:CHEBI_58945, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16247 ] . obo:CHEBI_63046 obo:IAO_0000115 "The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "emulgent", "emulgents", "emulsifiers" ; oboInOwl:id "CHEBI:63046" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "emulsifier" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_63161 obo:IAO_0000115 "A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glycosyl compounds" ; oboInOwl:id "CHEBI:63161" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "glycosyl compound" ; rdfs:subClassOf obo:CHEBI_63299 . obo:CHEBI_63248 obo:IAO_0000115 "A substance that removes electrons from another reactant in a redox reaction." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxidant", "oxidants", "oxidiser", "oxidisers", "oxidising agents", "oxidizer", "oxidizers", "oxidizing agent", "oxidizing agents" ; oboInOwl:id "CHEBI:63248" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "oxidising agent" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_63299 obo:IAO_0000115 "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrate derivatives", "derivatised carbohydrate", "derivatised carbohydrates", "derivatized carbohydrate", "derivatized carbohydrates" ; oboInOwl:id "CHEBI:63299" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbohydrate derivative" ; rdfs:subClassOf obo:CHEBI_78616, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16646 ] . obo:CHEBI_63332 obo:IAO_0000115 "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1)." ; oboInOwl:hasDbXref "Wikipedia:Alkaline_phosphatase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.3.1 (alkaline phosphatase) inhibitors", "EC 3.1.3.1 inhibitor", "EC 3.1.3.1 inhibitors", "alkaline phenyl phosphatase inhibitor", "alkaline phenyl phosphatase inhibitors", "alkaline phosphatase (EC 3.1.3.1) inhibitor", "alkaline phosphatase (EC 3.1.3.1) inhibitors", "alkaline phosphatase inhibitor", "alkaline phosphatase inhibitors", "alkaline phosphohydrolase inhibitor", "alkaline phosphohydrolase inhibitors", "alkaline phosphomonoesterase inhibitor", "alkaline phosphomonoesterase inhibitors", "glycerophosphatase inhibitor", "glycerophosphatase inhibitors", "orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitor", "orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitors", "phosphate-monoester phosphohydrolase (alkaline optimum) inhibitor", "phosphate-monoester phosphohydrolase (alkaline optimum) inhibitors", "phosphomonoesterase inhibitor", "phosphomonoesterase inhibitors" ; oboInOwl:id "CHEBI:63332" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.1.3.1 (alkaline phosphatase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76775 . obo:CHEBI_63367 obo:IAO_0000115 "A carbohydrate derivative that is formally obtained from a monosaccharide." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monosaccharide derivatives" ; oboInOwl:id "CHEBI:63367" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monosaccharide derivative" ; rdfs:subClassOf obo:CHEBI_63299, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_35381 ] . obo:CHEBI_63409 obo:IAO_0000115 "A monosaccharide derivative that is formally obtained from a pentose." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pentose derivatives" ; oboInOwl:id "CHEBI:63409" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pentose derivative" ; rdfs:subClassOf obo:CHEBI_63367, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_25901 ] . obo:CHEBI_63436 obo:IAO_0000115 "A carbohydrate derivative that is formally obtained from a carbohydrate acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrate acid derivatives" ; oboInOwl:id "CHEBI:63436" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbohydrate acid derivative" ; rdfs:subClassOf obo:CHEBI_63299, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33720 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_63551 ] . obo:CHEBI_63470 obo:IAO_0000115 "A sulfur-containing amino acid whose alpha-carboxylic acid group is ionized (not protonated)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfur-containing amino-acid anions" ; oboInOwl:id "CHEBI:63470" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "sulfur-containing amino-acid anion" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_26834 ] . obo:CHEBI_63490 obo:IAO_0000115 "A substance capable of undergoing rapid and highly exothermic decomposition." ; oboInOwl:hasDbXref "Wikipedia:Explosive_material" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "explosive compound", "explosive compounds", "explosive material", "explosives", "explosives chemical", "explosives chemicals" ; oboInOwl:id "CHEBI:63490" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "explosive" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_63510 obo:IAO_0000115 "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Na(+)/K(+)-transporting ATPase (EC 3.6.3.9)." ; oboInOwl:hasDbXref "Wikipedia:Sodium-potassium_ATPase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitors", "EC 3.6.3.9 inhibitor", "EC 3.6.3.9 inhibitors", "Na(+)/K(+)-ATPase inhibitor", "Na(+)/K(+)-ATPase inhibitors", "Na(+)/K(+)-pump inhibitor", "Na(+)/K(+)-pump inhibitors", "Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitor", "Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitors", "Na(+)/K(+)-transporting ATPase inhibitor", "Na(+)/K(+)-transporting ATPase inhibitors", "sodium pump inhibitor", "sodium pump inhibitors", "sodium-potassium adenosine triphosphatase inhibitor", "sodium-potassium adenosine triphosphatase inhibitors", "sodium-potassium pump inhibitor", "sodium-potassium pump inhibitors" ; oboInOwl:id "CHEBI:63510" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76895 . obo:CHEBI_63534 obo:IAO_0000115 "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." ; oboInOwl:hasDbXref "PMID:21822758", "PMID:21993877", "PMID:22005599", "PMID:22082101", "PMID:22153577", "PMID:22213370", "PMID:22218931", "PMID:22342987", "PMID:22371656" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoamines", "naturally occurring monoamine", "naturally occurring monoamines" ; oboInOwl:id "CHEBI:63534" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monoamine" ; rdfs:subClassOf obo:CHEBI_64365 . obo:CHEBI_63551 obo:IAO_0000115 "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrate acid anion derivative", "carbohydrate acid anion derivatives", "carbohydrate acid derivative anions" ; oboInOwl:id "CHEBI:63551" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbohydrate acid derivative anion" ; rdfs:subClassOf obo:CHEBI_29067, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33721 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_63436 ] . obo:CHEBI_63726 obo:IAO_0000115 "Any compound that can be used for the treatment of neurodegenerative disorders." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "neuroprotectant", "neuroprotectants", "neuroprotective agents" ; oboInOwl:id "CHEBI:63726" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "neuroprotective agent" ; rdfs:subClassOf obo:CHEBI_50267 . obo:CHEBI_63941 obo:IAO_0000115 "A macrocyclic lactone that is avermectin B1a in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the major component of ivermectin." ; chebi:charge "0" ; chebi:formula "C48H74O14" ; chebi:inchi "InChI=1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1" ; chebi:inchikey "AZSNMRSAGSSBNP-XPNPUAGNSA-N" ; chebi:mass "875.09280" ; chebi:monoisotopicmass "874.50786" ; chebi:smiles "[H][C@@]12C\\C=C(C)\\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\\C=C\\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(CC[C@H](C)[C@]([H])(O1)[C@@H](C)CC)O2)[C@]34O" ; oboInOwl:hasDbXref "CAS:71827-03-7", "PDBeChem:IVM", "PMID:2411323", "PMID:6125361", "PMID:6148214", "PMID:6547280", "Reaxys:4643153", "VSDB:1455" ; oboInOwl:hasExactSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-O-demethyl-22,23-dihydroavermectin A1a", "H2B1a", "avermectin H2B1a", "dihydroavermectin B1a", "ivermectin B1a" ; oboInOwl:id "CHEBI:63941" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "22,23-dihydroavermectin B1a" ; rdfs:subClassOf obo:CHEBI_63944, obo:CHEBI_72600, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_29534 ] . obo:CHEBI_63943 obo:IAO_0000115 "A macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin." ; chebi:charge "0" ; chebi:formula "C47H72O14" ; chebi:inchi "InChI=1S/C47H72O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,18,24-25,27,29-30,32-44,48-49,51H,15-17,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m0/s1" ; chebi:inchikey "VARHUCVRRNANBD-PVVXTEPVSA-N" ; chebi:mass "861.06620" ; chebi:monoisotopicmass "860.49221" ; chebi:smiles "[H][C@@]12C\\C=C(C)\\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\\C=C\\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(CC[C@H](C)[C@]([H])(O1)C(C)C)O2)[C@]34O" ; oboInOwl:hasDbXref "CAS:70209-81-3", "PMID:6125361", "PMID:6148214", "PMID:6895285", "PMID:6896121", "Reaxys:8183665" ; oboInOwl:hasExactSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-6'-(propan-2-yl)-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2B1b", "avermectin H2B1b", "dihydroavermectin B1b", "ivermectin B1b", "ivermectin component b1b" ; oboInOwl:id "CHEBI:63943" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "22,23-dihydroavermectin B1b" ; rdfs:subClassOf obo:CHEBI_63944, obo:CHEBI_72600, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_29537 ] . obo:CHEBI_63944 obo:IAO_0000115 "Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule." ; oboInOwl:hasAlternativeId "CHEBI:50333" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "macrocyclic lactones" ; oboInOwl:id "CHEBI:63944" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "macrocyclic lactone" ; rdfs:subClassOf obo:CHEBI_25000, obo:CHEBI_51026 . obo:CHEBI_64018 obo:IAO_0000115 "An agonist that selectively binds to and activates a protein kinase C receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "protein kinase C agonists" ; oboInOwl:id "CHEBI:64018" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "protein kinase C agonist" ; rdfs:subClassOf obo:CHEBI_64106 . obo:CHEBI_64047 obo:IAO_0000115 "Any substance which is added to food to preserve or enhance its flavour and/or appearance." ; oboInOwl:hasDbXref "Wikipedia:Food_additive" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food additives" ; oboInOwl:id "CHEBI:64047" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "food additive" ; rdfs:subClassOf obo:CHEBI_33232, obo:CHEBI_78295 . obo:CHEBI_64049 obo:IAO_0000115 "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." ; oboInOwl:hasDbXref "Wikipedia:Acidity_regulator" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acidity regulator", "acidity regulators", "food acidity regulators", "pH control agent", "pH control agents" ; oboInOwl:id "CHEBI:64049" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "food acidity regulator" ; rdfs:subClassOf obo:CHEBI_64047 . obo:CHEBI_64106 obo:IAO_0000115 "An agonist that selectively binds to and activates a protein kinase receptor." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "protein kinase agonists" ; oboInOwl:id "CHEBI:64106" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "protein kinase agonist" ; rdfs:subClassOf obo:CHEBI_48705 . obo:CHEBI_64203 obo:IAO_0000115 "A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively)." ; chebi:charge "0" ; chebi:formula "C20H24N2S2" ; chebi:inchi "InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3" ; chebi:inchikey "RLJFTICUTYVZDG-UHFFFAOYSA-N" ; chebi:mass "356.54800" ; chebi:monoisotopicmass "356.13809" ; chebi:smiles "CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1" ; oboInOwl:hasDbXref "CAS:20229-30-5", "HMDB:HMDB0254534", "LINCS:LSM-4320", "PMID:18033297", "PMID:18996971", "PMID:19837141", "PMID:19995401", "PMID:20171242", "PMID:20233210", "PMID:20331882", "PMID:20547148", "PMID:21062995", "PMID:21403818", "PMID:21514998", "PMID:21964383", "Patent:NL6608618", "Patent:US3379729", "Patent:US4444778", "Patent:US6331536", "Reaxys:626221", "Wikipedia:Metitepine" ; oboInOwl:hasExactSynonym "1-methyl-4-[8-(methylsulfanyl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+-)-1-(10,11-Dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methylpiperazine", "(+-)-10-(4-Methylpiperazinyl)-8-(methylthio)-10,11-dihydrodibenzo(b,f)thiepin", "(+-)-8-Methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin", "1-(10,11-Dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methylpiperazine", "1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine", "Methiothepine", "metitepina", "metitepine", "metitepinum" ; oboInOwl:id "CHEBI:64203" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methiothepin" ; rdfs:subClassOf obo:CHEBI_35683, obo:CHEBI_38924, obo:CHEBI_46845, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35476 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48279 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48561 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_64204 ] . obo:CHEBI_64204 obo:IAO_0000115 "A doubly-charged organic cation arising from protonation of the two tertiary amino functions of methiothepin." ; chebi:charge "+2" ; chebi:formula "C20H26N2S2" ; chebi:inchi "InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3/p+2" ; chebi:inchikey "RLJFTICUTYVZDG-UHFFFAOYSA-P" ; chebi:mass "358.56400" ; chebi:monoisotopicmass "358.15264" ; chebi:smiles "CSc1ccc2Sc3ccccc3CC([NH+]3CC[NH+](C)CC3)c2c1" ; oboInOwl:hasExactSynonym "1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazinediium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methiothepin cation" ; oboInOwl:id "CHEBI:64204" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methiothepin(2+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_64203 ] . obo:CHEBI_64228 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 11-methyldodec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C36H58N4O16" ; chebi:inchi "InChI=1S/C36H58N4O16/c1-17(2)11-9-7-5-4-6-8-10-12-22(44)38-25-29(49)26(46)20(53-35(25)56-34-24(37-18(3)42)28(48)27(47)21(16-41)54-34)15-19(43)32-30(50)31(51)33(55-32)40-14-13-23(45)39-36(40)52/h10,12-14,17,19-21,24-35,41,43,46-51H,4-9,11,15-16H2,1-3H3,(H,37,42)(H,38,44)(H,39,45,52)/b12-10+/t19-,20-,21-,24-,25-,26+,27-,28-,29-,30+,31-,32-,33-,34-,35+/m1/s1" ; chebi:inchikey "FIIRBPHYBLFBSD-MZPZZZQLSA-N" ; chebi:mass "802.86290" ; chebi:monoisotopicmass "802.38478" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-11-methyldodec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(11-methyldodec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin I" ; oboInOwl:id "CHEBI:64228" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin A0" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64237 obo:IAO_0000115 "An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitors", "EC 2.7.8.15 inhibitor", "EC 2.7.8.15 inhibitors", "GlcNAc-1-P transferase inhibitor", "GlcNAc-1-P transferase inhibitors", "N-acetylglucosamine phosphotransferase inhibitor", "N-acetylglucosamine transferase inhibitors", "N-acetylglucosamine-1-phosphate transferase inhibitor", "N-acetylglucosamine-1-phosphate transferase inhibitors", "UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitor", "UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitors", "UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitor", "UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitors", "UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitor", "UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitors", "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitor", "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitors", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitor", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitors", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitors", "UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitor", "UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitors", "UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitor", "UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitors", "chitobiosylpyrophosphoryldolichol synthase inhibitor", "chitobiosylpyrophosphoryldolichol synthase inhibitors", "dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitor", "dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitors", "uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitor", "uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitors" ; oboInOwl:id "CHEBI:64237" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76816 . obo:CHEBI_64245 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 12-methyltridec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C37H60N4O16" ; chebi:inchi "InChI=1S/C37H60N4O16/c1-18(2)12-10-8-6-4-5-7-9-11-13-23(45)39-26-30(50)27(47)21(54-36(26)57-35-25(38-19(3)43)29(49)28(48)22(17-42)55-35)16-20(44)33-31(51)32(52)34(56-33)41-15-14-24(46)40-37(41)53/h11,13-15,18,20-22,25-36,42,44,47-52H,4-10,12,16-17H2,1-3H3,(H,38,43)(H,39,45)(H,40,46,53)/b13-11+/t20-,21-,22-,25-,26-,27+,28-,29-,30-,31+,32-,33-,34-,35-,36+/m1/s1" ; chebi:inchikey "YJQCOFNZVFGCAF-LLXUUZRASA-N" ; chebi:mass "816.88950" ; chebi:monoisotopicmass "816.40043" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468", "Reaxys:8183793" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-12-methyltridec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(12-methyltridec-2-enamido)-beta-D-galactopyranos-6-yl]uridine", "tunicamycin A1" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin C", "tunicamycin II" ; oboInOwl:id "CHEBI:64245" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin A1" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64246 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a tetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C37H60N4O16" ; chebi:inchi "InChI=1S/C37H60N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-23(45)39-26-30(50)27(47)21(54-36(26)57-35-25(38-19(2)43)29(49)28(48)22(18-42)55-35)17-20(44)33-31(51)32(52)34(56-33)41-16-15-24(46)40-37(41)53/h13-16,20-22,25-36,42,44,47-52H,3-12,17-18H2,1-2H3,(H,38,43)(H,39,45)(H,40,46,53)/b14-13+/t20-,21-,22-,25-,26-,27+,28-,29-,30-,31+,32-,33-,34-,35-,36+/m1/s1" ; chebi:inchikey "MMDMXWRRAOLMDC-ZNZAGFTISA-N" ; chebi:mass "816.88950" ; chebi:monoisotopicmass "816.40043" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]tetradec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(tetradec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin III" ; oboInOwl:id "CHEBI:64246" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin A2" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64248 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a pentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C38H62N4O16" ; chebi:inchi "InChI=1S/C38H62N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(2)44)30(50)29(49)23(19-43)56-36)18-21(45)34-32(52)33(53)35(57-34)42-17-16-25(47)41-38(42)54/h14-17,21-23,26-37,43,45,48-53H,3-13,18-19H2,1-2H3,(H,39,44)(H,40,46)(H,41,47,54)/b15-14+/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1" ; chebi:inchikey "QYVMTFXNKNWWFX-YGTZKZKGSA-N" ; chebi:mass "830.91610" ; chebi:monoisotopicmass "830.41608" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]pentadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(pentadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin IV" ; oboInOwl:id "CHEBI:64248" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin B1" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64250 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 13-methyltetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C38H62N4O16" ; chebi:inchi "InChI=1S/C38H62N4O16/c1-19(2)13-11-9-7-5-4-6-8-10-12-14-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(3)44)30(50)29(49)23(18-43)56-36)17-21(45)34-32(52)33(53)35(57-34)42-16-15-25(47)41-38(42)54/h12,14-16,19,21-23,26-37,43,45,48-53H,4-11,13,17-18H2,1-3H3,(H,39,44)(H,40,46)(H,41,47,54)/b14-12+/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1" ; chebi:inchikey "MEYZYGMYMLNUHJ-DIRMKAHISA-N" ; chebi:mass "830.91610" ; chebi:monoisotopicmass "830.41608" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468", "Reaxys:5711197" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-13-methyltetradec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(13-methyltetradec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin A", "tunicamycin V" ; oboInOwl:id "CHEBI:64250" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin B2" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64255 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 13-methyltetradecanoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C38H64N4O16" ; chebi:inchi "InChI=1S/C38H64N4O16/c1-19(2)13-11-9-7-5-4-6-8-10-12-14-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(3)44)30(50)29(49)23(18-43)56-36)17-21(45)34-32(52)33(53)35(57-34)42-16-15-25(47)41-38(42)54/h15-16,19,21-23,26-37,43,45,48-53H,4-14,17-18H2,1-3H3,(H,39,44)(H,40,46)(H,41,47,54)/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1" ; chebi:inchikey "XAFNQFHOQPRGAK-KTVOANSYSA-N" ; chebi:mass "832.93200" ; chebi:monoisotopicmass "832.43173" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)CCCCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-13-methyltetradecanamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(13-methyltetradecanamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin VI" ; oboInOwl:id "CHEBI:64255" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin B3" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64256 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 14-methylpentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C39H64N4O16" ; chebi:inchi "InChI=1S/C39H64N4O16/c1-20(2)14-12-10-8-6-4-5-7-9-11-13-15-25(47)41-28-32(52)29(49)23(56-38(28)59-37-27(40-21(3)45)31(51)30(50)24(19-44)57-37)18-22(46)35-33(53)34(54)36(58-35)43-17-16-26(48)42-39(43)55/h13,15-17,20,22-24,27-38,44,46,49-54H,4-12,14,18-19H2,1-3H3,(H,40,45)(H,41,47)(H,42,48,55)/b15-13+/t22-,23-,24-,27-,28-,29+,30-,31-,32-,33+,34-,35-,36-,37-,38+/m1/s1" ; chebi:inchikey "ZOCXUHJGZXXIGQ-NPXWYGMKSA-N" ; chebi:mass "844.94270" ; chebi:monoisotopicmass "844.43173" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "CAS:66081-36-5", "Chemspider:27471426", "MetaCyc:CPD-19373", "PMID:29844049", "PMID:29973921", "PMID:30445836", "PMID:33636028", "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-14-methylpentadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(14-methylpentadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "corynetoxin U-16I", "tunicamycin B", "tunicamycin VII" ; oboInOwl:id "CHEBI:64256" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin C1" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76969 ] . obo:CHEBI_64257 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a hexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C39H64N4O16" ; chebi:inchi "InChI=1S/C39H64N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(47)41-28-32(52)29(49)23(56-38(28)59-37-27(40-21(2)45)31(51)30(50)24(20-44)57-37)19-22(46)35-33(53)34(54)36(58-35)43-18-17-26(48)42-39(43)55/h15-18,22-24,27-38,44,46,49-54H,3-14,19-20H2,1-2H3,(H,40,45)(H,41,47)(H,42,48,55)/b16-15+/t22-,23-,24-,27-,28-,29+,30-,31-,32-,33+,34-,35-,36-,37-,38+/m1/s1" ; chebi:inchikey "NKDRZEIENXWUCE-VDIUWDQWSA-N" ; chebi:mass "844.94270" ; chebi:monoisotopicmass "844.43173" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]hexadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(hexadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:64257" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin C2" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64271 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a heptadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C40H66N4O16" ; chebi:inchi "InChI=1S/C40H66N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-26(48)42-29-33(53)30(50)24(57-39(29)60-38-28(41-22(2)46)32(52)31(51)25(21-45)58-38)20-23(47)36-34(54)35(55)37(59-36)44-19-18-27(49)43-40(44)56/h16-19,23-25,28-39,45,47,50-55H,3-15,20-21H2,1-2H3,(H,41,46)(H,42,48)(H,43,49,56)/b17-16+/t23-,24-,25-,28-,29-,30+,31-,32-,33-,34+,35-,36-,37-,38-,39+/m1/s1" ; chebi:inchikey "DYGXSHBNTGWENQ-YTXMDVFISA-N" ; chebi:mass "858.96920" ; chebi:monoisotopicmass "858.44738" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]heptadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(heptadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:64271" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin D1" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64272 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 15-methylhexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C40H66N4O16" ; chebi:inchi "InChI=1S/C40H66N4O16/c1-21(2)15-13-11-9-7-5-4-6-8-10-12-14-16-26(48)42-29-33(53)30(50)24(57-39(29)60-38-28(41-22(3)46)32(52)31(51)25(20-45)58-38)19-23(47)36-34(54)35(55)37(59-36)44-18-17-27(49)43-40(44)56/h14,16-18,21,23-25,28-39,45,47,50-55H,4-13,15,19-20H2,1-3H3,(H,41,46)(H,42,48)(H,43,49,56)/b16-14+/t23-,24-,25-,28-,29-,30+,31-,32-,33-,34+,35-,36-,37-,38-,39+/m1/s1" ; chebi:inchikey "XCEPHNBEHQJSSB-LGJGITPNSA-N" ; chebi:mass "858.96920" ; chebi:monoisotopicmass "858.44738" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-15-methylhexadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(15-methylhexadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:64272" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "tunicamycin D2" ; rdfs:subClassOf obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_6432 obo:IAO_0000115 "A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has S configuration. It is used (generally as the monohydrochloride salt) to treat parasitic worm infections in pigs, sheep and cattle and was formerly used in humans as an adjuvant to chemotherapy for the treatment of various cancers. It is also widely used as an adulterant to coccaine." ; chebi:charge "0" ; chebi:formula "C11H12N2S" ; chebi:inchi "InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1" ; chebi:inchikey "HLFSDGLLUJUHTE-SNVBAGLBSA-N" ; chebi:mass "204.29100" ; chebi:monoisotopicmass "204.07212" ; chebi:smiles "C1CN2C[C@@H](N=C2S1)c1ccccc1" ; oboInOwl:hasDbXref "CAS:14769-73-4", "DrugBank:DB00848", "Drug_Central:1561", "HMDB:HMDB0014986", "KEGG:C07070", "KEGG:D08114", "LINCS:LSM-6655", "PMID:10701095", "PMID:12232676", "PMID:12749943", "PMID:15109274", "PMID:1618599", "PMID:17608969", "PMID:189006", "PMID:2050823", "PMID:22337783", "PMID:22607692", "PMID:23041983", "PMID:23152411", "PMID:23543977", "PMID:23577329", "PMID:23649929", "PMID:23921349", "PMID:24365689", "PMID:24440755", "PMID:365327", "PMID:366135", "PMID:366137", "PMID:669135", "PMID:6995092", "PMID:6995094", "PMID:7051554", "PMID:827785", "Patent:US3274209", "Patent:US3565907", "Patent:US3579530", "Reaxys:4233256", "VSDB:1798", "Wikipedia:Levamisole" ; oboInOwl:hasExactSynonym "(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole", "(-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole", "(-)-tetramisole", "(S)-(-)-levamisole", "(S)-(-)-tetramisole", "(S)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole", "Ketrax", "Lepuron", "Levomysol", "Levovermax", "Totalon", "Wormicid", "levamisol", "levamisole", "levamisolum" ; oboInOwl:id "CHEBI:6432" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "levamisole" ; rdfs:subClassOf obo:CHEBI_77278, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35444 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35842 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50847 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63332 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_77282 ] . obo:CHEBI_64365 obo:IAO_0000115 "An organic amino compound in which an aminoalkyl group is linked to an arene." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aralkylamino compounds" ; oboInOwl:id "CHEBI:64365" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aralkylamino compound" ; rdfs:subClassOf obo:CHEBI_50047 . obo:CHEBI_64459 obo:IAO_0000115 "An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "biaryls" ; oboInOwl:id "CHEBI:64459" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "biaryl" ; rdfs:subClassOf obo:CHEBI_33659 . obo:CHEBI_64577 obo:IAO_0000115 "A food additive which is added to flour or dough to improve baking quality and/or colour." ; oboInOwl:hasDbXref "Wikipedia:Flour_treatment_agent" ; oboInOwl:hasExactSynonym "flour treatment agent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dough improver", "dough improvers", "improving agent", "improving agents" ; oboInOwl:id "CHEBI:64577" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "flour treatment agent" ; rdfs:subClassOf obo:CHEBI_64047 . obo:CHEBI_64628 obo:IAO_0000115 "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14." ; chebi:charge "0" ; chebi:formula "C76H104N18O19S2" ; chebi:inchi "InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1" ; chebi:inchikey "NHXLMOGPVYXJNR-ATOGVRKGSA-N" ; chebi:mass "1637.87800" ; chebi:monoisotopicmass "1636.71666" ; chebi:smiles "C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N" ; oboInOwl:hasDbXref "CAS:38916-34-6", "Drug_Central:2997", "HMDB:HMDB0013072", "KEGG:C16022", "KEGG:D07431", "LINCS:LSM-5326", "PMID:21922516", "PMID:22129035", "PMID:22147011", "PMID:22251942", "PMID:22483686", "PMID:22509294", "Reaxys:10148626", "Wikipedia:Somatostatin" ; oboInOwl:hasExactSynonym "L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]", "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide", "Somatostatin-1", "Somatostatin-14", "Synthetic growth hormone release-inhibiting hormone", "somatostatin", "somatostatina", "somatostatine", "somatostatinum" ; oboInOwl:id "CHEBI:64628" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "somatostatin" ; rdfs:subClassOf obo:CHEBI_24533, obo:CHEBI_25905 . obo:CHEBI_64641 obo:IAO_0000115 "An inorganic cation with a valency of two." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:64641" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "divalent inorganic cation" ; rdfs:subClassOf obo:CHEBI_36915 . obo:CHEBI_64708 obo:IAO_0000115 "An organic molecular entity containing a single carbon atom (C1)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "one-carbon compounds" ; oboInOwl:id "CHEBI:64708" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "one-carbon compound" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_64709 obo:IAO_0000115 "Any organic molecular entity that is acidic and contains carbon in covalent linkage." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic acids" ; oboInOwl:id "CHEBI:64709" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic acid" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_64857 obo:IAO_0000115 "The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it." ; oboInOwl:hasDbXref "Wikipedia:Cosmetics" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cosmetic component", "cosmetics" ; oboInOwl:id "CHEBI:64857" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cosmetic" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_64909 obo:IAO_0000115 "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." ; oboInOwl:hasDbXref "Wikipedia:Poison" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "poisonous agent", "poisonous agents", "poisonous substance", "poisonous substances", "poisons", "toxic agent", "toxic agents", "toxic substance", "toxic substances" ; oboInOwl:id "CHEBI:64909" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "poison" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_64911 obo:IAO_0000115 "Any compound that inhibits cell division (mitosis)." ; oboInOwl:hasDbXref "Wikipedia:Mitotic_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimitotics", "mitosis inhibitor", "mitosis inhibitors", "mitotic inhibitor", "mitotic inhibitors" ; oboInOwl:id "CHEBI:64911" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimitotic" ; rdfs:subClassOf obo:CHEBI_52210 . obo:CHEBI_64915 obo:IAO_0000115 "An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antiplasmodial agent", "antiplasmodial agents", "antiplasmodial drugs", "antiplasmodium agent", "antiplasmodium agents", "antiplasmodium drug", "antiplasmodium drugs" ; oboInOwl:id "CHEBI:64915" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antiplasmodial drug" ; rdfs:subClassOf obo:CHEBI_35820 . obo:CHEBI_65212 obo:IAO_0000115 "A carbohydrate derivative that is any derivative of a polysaccharide." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polysaccharide derivatives" ; oboInOwl:id "CHEBI:65212" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "polysaccharide derivative" ; rdfs:subClassOf obo:CHEBI_167559, obo:CHEBI_33694, obo:CHEBI_63299, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_18154 ] . obo:CHEBI_65255 obo:IAO_0000115 "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food preservatives" ; oboInOwl:id "CHEBI:65255" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "food preservative" ; rdfs:subClassOf obo:CHEBI_64047 . obo:CHEBI_65256 obo:IAO_0000115 "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimicrobial food preservatives", "antimicrobial preservative", "antimicrobial preservatives" ; oboInOwl:id "CHEBI:65256" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "antimicrobial food preservative" ; rdfs:subClassOf obo:CHEBI_33281, obo:CHEBI_65255 . obo:CHEBI_65259 obo:IAO_0000115 "A compound that inhibits the action of gamma-aminobutyric acid." ; oboInOwl:hasDbXref "Wikipedia:GABA_antagonist" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "GABA antagonists", "gamma-aminobutyric acid receptor antagonist", "gamma-aminobutyric acid receptor antagonists" ; oboInOwl:id "CHEBI:65259" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "GABA antagonist" ; rdfs:subClassOf obo:CHEBI_48706, obo:CHEBI_51374 . obo:CHEBI_65296 obo:IAO_0000115 "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "H3NR" ; chebi:mass "17.031" ; chebi:monoisotopicmass "17.02655" ; chebi:smiles "[NH3+][*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a primary amine", "substituted ammonium" ; oboInOwl:id "CHEBI:65296" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "primary ammonium ion" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_50994 ] . obo:CHEBI_67079 obo:IAO_0000115 "Any compound that has anti-inflammatory effects." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-inflammatory agents", "antiinflammatory agent", "antiinflammatory agents" ; oboInOwl:id "CHEBI:67079" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "anti-inflammatory agent" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_67114 obo:IAO_0000115 "A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction." ; oboInOwl:hasDbXref "PMID:30679133", "PMID:30684528", "PMID:31840405", "PMID:8597061", "Wikipedia:Ryanodine_receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RyR activator", "RyR activators", "RyR agonist", "RyR agonists", "RyRs activator", "RyRs agonist", "ryanodine receptor activator", "ryanodine receptor activators" ; oboInOwl:id "CHEBI:67114" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ryanodine receptor agonist" ; rdfs:subClassOf obo:CHEBI_38809 . obo:CHEBI_67142 obo:IAO_0000115 "A molecule that can substitute for a normal nucleobase in nucleic acids." ; oboInOwl:hasDbXref "Wikipedia:Base_analog" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "base analog", "base analogs", "base analogue", "base analogues", "nucleobase analog", "nucleobase analogs", "nucleobase analogues" ; oboInOwl:id "CHEBI:67142" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "nucleobase analogue" ; rdfs:subClassOf obo:CHEBI_33832 . obo:CHEBI_6835 obo:IAO_0000115 "A carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime." ; chebi:charge "0" ; chebi:formula "C5H10N2O2S" ; chebi:inchi "InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)" ; chebi:inchikey "UHXUZOCRWCRNSJ-UHFFFAOYSA-N" ; chebi:mass "162.21118" ; chebi:monoisotopicmass "162.04630" ; chebi:smiles "CNC(=O)ON=C(C)SC" ; oboInOwl:hasDbXref "Beilstein:2042050", "CAS:16752-77-5", "HMDB:HMDB0031804", "KEGG:C11196", "LINCS:LSM-24991", "PMID:11327381", "PMID:11758270", "PPDB:458", "Pesticides:methomyl", "Reaxys:2042050", "Wikipedia:Methomyl" ; oboInOwl:hasExactSynonym "Methomyl", "methyl N-(methylcarbamoyloxy)ethanimidothioate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-(Methylthio)acetaldehyde O-methylcarbamoyloxime", "1-(Methylthio)ethylideneamino methylcarbamate", "Lannate", "Methomyl lannate", "N-(((methylamino)carbonyl)oxy)ethanimidothioic acid methyl ester", "S-Methyl N-(methylcarbamoyloxy)thioacetimidate" ; oboInOwl:id "CHEBI:6835" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methomyl" ; rdfs:subClassOf obo:CHEBI_22327, obo:CHEBI_23003, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22153 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24852 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25491 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33286 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37733 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38462 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_38534 ], [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_45379 ] . obo:CHEBI_68452 obo:IAO_0000115 "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen." ; oboInOwl:hasDbXref "Wikipedia:Azole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "azoles" ; oboInOwl:id "CHEBI:68452" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "azole" ; rdfs:subClassOf obo:CHEBI_38101, obo:CHEBI_38179 . obo:CHEBI_68495 obo:IAO_0000115 "Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Type I cell-death inducer", "Type I cell-death inducers", "Type I programmed cell-death inducer", "Type I programmed cell-death inducers", "apoptosis inducers" ; oboInOwl:id "CHEBI:68495" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "apoptosis inducer" ; rdfs:subClassOf obo:CHEBI_52206 . obo:CHEBI_7035 obo:IAO_0000115 "A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita." ; chebi:charge "0" ; chebi:formula "C4H6N2O2" ; chebi:inchi "InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)" ; chebi:inchikey "ZJQHPWUVQPJPQT-UHFFFAOYSA-N" ; chebi:mass "114.10260" ; chebi:monoisotopicmass "114.04293" ; chebi:smiles "NCc1cc(=O)[nH]o1" ; oboInOwl:hasDbXref "Beilstein:774694", "CAS:2763-96-4", "KEGG:C08311", "KNApSAcK:C00001423", "PMID:18599311", "PMID:21427702", "PMID:21751026", "PMID:2181052", "PMID:22049436", "PMID:24259680", "PMID:24316475", "PMID:24473816", "Reaxys:774694", "Wikipedia:Muscimol" ; oboInOwl:hasExactSynonym "5-(aminomethyl)-1,2-oxazol-3(2H)-one", "Muscimol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-(aminomethyl)-3(2H)-isoxazolone" ; oboInOwl:id "CHEBI:7035" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "muscimol" ; rdfs:subClassOf obo:CHEBI_22315, obo:CHEBI_50994, obo:CHEBI_55373, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_146270 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_51373 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76946 ] . obo:CHEBI_71232 obo:IAO_0000115 "An antagonist at any adenosine receptor." ; oboInOwl:hasDbXref "Wikipedia:Adenosine_receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenosine receptor antagonists" ; oboInOwl:id "CHEBI:71232" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "adenosine receptor antagonist" ; rdfs:subClassOf obo:CHEBI_48706 . obo:CHEBI_71300 obo:IAO_0000115 "An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)" ; oboInOwl:hasDbXref "Wikipedia:Transferase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2 inhibitor", "EC 2 inhibitors", "EC 2.* (transferase) inhibitors", "EC 2.* inhibitor", "EC 2.* inhibitors", "transferase inhibitor", "transferase inhibitors" ; oboInOwl:id "CHEBI:71300" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.* (transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_71666 obo:IAO_0000115 "An amino-acid anion in which the amino group is situated gamma- to the carboxylate group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gamma-amino acid anions" ; oboInOwl:id "CHEBI:71666" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "gamma-amino acid anion" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33707 ] . obo:CHEBI_72587 obo:IAO_0000115 "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C8H12NO3" ; chebi:inchi "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1" ; chebi:inchikey "SFLSHLFXELFNJZ-QMMMGPOBSA-O" ; chebi:mass "170.187" ; chebi:monoisotopicmass "170.08117" ; chebi:smiles "C=1(C=CC(=CC1O)[C@H](C[NH3+])O)O" ; oboInOwl:hasDbXref "PDBeChem:E5E" ; oboInOwl:hasExactSynonym "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(R)-noradrenaline", "(R)-noradrenaline cation", "(R)-noradrenalinium cation", "(R)-noradrenalinium(1+)" ; oboInOwl:id "CHEBI:72587" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(R)-noradrenaline(1+)" ; rdfs:subClassOf obo:CHEBI_166902, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_18357 ] . obo:CHEBI_72600 obo:IAO_0000115 "A cyclic ketal in which the ketal carbon is the only common atom of two rings." ; oboInOwl:hasDbXref "PMID:19262920", "PMID:20024126", "PMID:21076755", "PMID:21604735", "PMID:21860857", "PMID:22421755" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "spiroacetal", "spiroacetals", "spiroketals" ; oboInOwl:id "CHEBI:72600" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "spiroketal" ; rdfs:subClassOf obo:CHEBI_37948, obo:CHEBI_59779 . obo:CHEBI_72695 obo:IAO_0000115 "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic compound", "organic compounds", "organic molecules" ; oboInOwl:id "CHEBI:72695" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic molecule" ; rdfs:subClassOf obo:CHEBI_25367, obo:CHEBI_50860 . obo:CHEBI_72813 obo:IAO_0000115 "A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment." ; oboInOwl:hasDbXref "MetaCyc:Exopolysaccharides", "PMID:11160795", "PMID:11785425", "PMID:1444258", "PMID:15738217", "PMID:16075348", "PMID:17440912", "PMID:18097339", "PMID:19453747", "PMID:20172021", "PMID:20631870", "PMID:20718297", "PMID:2688547", "PMID:6354590", "Wikipedia:Exopolysaccharide", "Wikipedia:Extracellular_polymeric_substance" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "exopolysaccharides", "extracellular polymeric substance", "extracellular polymeric substances" ; oboInOwl:id "CHEBI:72813" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "exopolysaccharide" ; rdfs:subClassOf obo:CHEBI_33694 . obo:CHEBI_73216 obo:IAO_0000115 "Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*)." ; oboInOwl:hasAlternativeId "CHEBI:76765" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.6 inhibitor", "EC 3.6 inhibitors", "EC 3.6.* (hydrolases acting on acid anhydrides) inhibitors", "EC 3.6.* inhibitor", "EC 3.6.* inhibitors", "EC 3.6.*.* inhibitor", "EC 3.6.*.* inhibitors", "acid anhydride hydrolase inhibitor", "acid anhydride hydrolase inhibitors", "inhibitor of hydrolase acting on acid anhydride (EC 3.6.*)", "inhibitors of hydrolase acting on acid anhydride (EC 3.6.*)" ; oboInOwl:id "CHEBI:73216" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor" ; rdfs:subClassOf obo:CHEBI_76759 . obo:CHEBI_73333 obo:IAO_0000115 "An acaricide that kills mites of the genus Sarcoptes." ; oboInOwl:hasDbXref "Wikipedia:Scabicide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "scabicides" ; oboInOwl:id "CHEBI:73333" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "scabicide" ; rdfs:subClassOf obo:CHEBI_22153 . obo:CHEBI_73398 obo:IAO_0000115 "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." ; chebi:charge "0" ; chebi:formula "C8N" ; chebi:mass "110.09230" ; chebi:monoisotopicmass "110.00307" ; chebi:smiles "C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:73398" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "indole skeleton" ; rdfs:subClassOf obo:CHEBI_73541 . obo:CHEBI_73541 obo:IAO_0000115 "A bicyclic organic group that contains both carbon and hetero atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic heterobicyclic rings" ; oboInOwl:id "CHEBI:73541" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organic heterobicyclic ring" ; rdfs:subClassOf obo:CHEBI_52845 . obo:CHEBI_73693 obo:IAO_0000115 "A carbonyl compound produced as a water-soluble byproduct when fatty acids are broken down for energy in the liver. There are three endogenous ketone bodies: acetone, acetoacetic acid, and (R)-3-hydroxybutyric acid; others may be produced as a result of the metabolism of synthetic triglycerides." ; oboInOwl:hasDbXref "PMID:10634967", "PMID:19159745", "PMID:22259088", "PMID:22268909", "PMID:22524563", "PMID:22879057", "PMID:23082721", "PMID:23148246", "PMID:23396451", "PMID:23466063", "PMID:23557707", "Wikipedia:Ketone_body" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ketone bodies" ; oboInOwl:id "CHEBI:73693" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "ketone body" ; rdfs:subClassOf obo:CHEBI_36586, obo:CHEBI_61697, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25212 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63726 ] . obo:CHEBI_74213 obo:IAO_0000115 "An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1)." ; oboInOwl:hasDbXref "Wikipedia:Ribonucleoside-diphosphate_reductase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitor", "2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitors", "ADP reductase inhibitor", "ADP reductase inhibitors", "CDP reductase inhibitor", "CDP reductase inhibitors", "EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitors", "EC 1.17.4.1 inhibitor", "EC 1.17.4.1 inhibitors", "RR inhibitor", "RR inhibitors", "UDP reductase inhibitor", "UDP reductase inhibitors", "nucleoside diphosphate reductase inhibitor", "nucleoside diphosphate reductase inhibitors", "ribonucleoside diphosphate reductase inhibitor", "ribonucleoside diphosphate reductase inhibitors", "ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitor", "ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitors", "ribonucleoside-diphosphate reductase inhibitor", "ribonucleoside-diphosphate reductase inhibitors", "ribonucleotide diphosphate reductase inhibitor", "ribonucleotide diphosphate reductase inhibitors", "ribonucleotide reductase inhibitor", "ribonucleotide reductase inhibitors" ; oboInOwl:id "CHEBI:74213" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76848 . obo:CHEBI_74634 obo:IAO_0000115 "Any steroid lactone that is a C23 steroid with a five-membered lactone ring at C-17 and its substituted derivatives. They form the aglycone constituents of cardiac glycosides." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:74634" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cardenolides" ; rdfs:subClassOf obo:CHEBI_26766, obo:CHEBI_50523 . obo:CHEBI_74783 obo:IAO_0000115 "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions." ; oboInOwl:hasDbXref "Wikipedia:Astringent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adstringent", "adstringents", "astringents" ; oboInOwl:id "CHEBI:74783" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "astringent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_75763 obo:IAO_0000115 "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "eukaryotic metabolites" ; oboInOwl:id "CHEBI:75763" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "eukaryotic metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_75767 obo:IAO_0000115 "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." ; oboInOwl:hasAlternativeId "CHEBI:77721", "CHEBI:77743" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "animal metabolites" ; oboInOwl:id "CHEBI:75767" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "animal metabolite" ; rdfs:subClassOf obo:CHEBI_75763 . obo:CHEBI_75768 obo:IAO_0000115 "Any animal metabolite produced during a metabolic reaction in mammals." ; oboInOwl:hasAlternativeId "CHEBI:77464", "CHEBI:77744" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mammalian metabolites" ; oboInOwl:id "CHEBI:75768" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mammalian metabolite" ; rdfs:subClassOf obo:CHEBI_75767 . obo:CHEBI_75771 obo:IAO_0000115 "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Mus musculus metabolite", "Mus musculus metabolites", "mouse metabolites" ; oboInOwl:id "CHEBI:75771" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "mouse metabolite" ; rdfs:subClassOf obo:CHEBI_75768 . obo:CHEBI_75772 obo:IAO_0000115 "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." ; oboInOwl:hasAlternativeId "CHEBI:76949", "CHEBI:76951" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "S. cerevisiae metabolite", "S. cerevisiae metabolites", "S. cerevisiae secondary metabolite", "S. cerevisiae secondary metabolites", "Saccharomyces cerevisiae metabolites", "Saccharomyces cerevisiae secondary metabolites", "baker's yeast metabolite", "baker's yeast metabolites", "baker's yeast secondary metabolite", "baker's yeast secondary metabolites" ; oboInOwl:id "CHEBI:75772" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "Saccharomyces cerevisiae metabolite" ; rdfs:subClassOf obo:CHEBI_76946 . obo:CHEBI_75787 obo:IAO_0000115 "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "prokaryotic metabolites" ; oboInOwl:id "CHEBI:75787" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "prokaryotic metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_76206 obo:IAO_0000115 "Any metabolite produced by metabolism of a xenobiotic compound." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "xenobiotic metabolites" ; oboInOwl:id "CHEBI:76206" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "xenobiotic metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_76413 obo:IAO_0000115 "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'." ; oboInOwl:hasDbXref "Wikipedia:Greenhouse_gas" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "greenhouse gases" ; oboInOwl:id "CHEBI:76413" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "greenhouse gas" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_76414 obo:IAO_0000115 "A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans." ; oboInOwl:hasDbXref "PMID:22519407", "PMID:24001847" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "propellants" ; oboInOwl:id "CHEBI:76414" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "propellant" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_76507 obo:IAO_0000115 "Any metabolite produced during a metabolic reaction in marine macro- and microorganisms." ; oboInOwl:hasAlternativeId "CHEBI:77078" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "marine metabolites" ; oboInOwl:id "CHEBI:76507" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "marine metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_76661 obo:IAO_0000115 "A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.3.* (acyltransferase) inhibitors", "EC 2.3.* inhibitor", "EC 2.3.* inhibitors", "acyltransferase inhibitor", "acyltransferase inhibitors" ; oboInOwl:id "CHEBI:76661" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.3.* (acyltransferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_71300 . obo:CHEBI_76663 obo:IAO_0000115 "A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitors", "EC 2.5.1.* inhibitor", "EC 2.5.1.* inhibitors", "alkyl/aryl (non-methyl) transferase inhibitor", "alkyl/aryl (non-methyl) transferase inhibitors", "non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitor", "non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitors", "non-methyl alkyl/aryl transferase inhibitor", "non-methyl alkyl/aryl transferase inhibitors", "non-methyl-alkyl or aryl transferase inhibitor", "non-methyl-alkyl or aryl transferase inhibitors" ; oboInOwl:id "CHEBI:76663" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76834 . obo:CHEBI_76668 obo:IAO_0000115 "A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.* (P-containing group transferase) inhibitors", "EC 2.7.* (phosphorus-containing group transferase) inhibitor", "EC 2.7.* (phosphorus-containing group transferase) inhibitors", "EC 2.7.* inhibitor", "EC 2.7.* inhibitors", "phosphorus-containing group transferase (EC 2.7.*) inhibitor", "phosphorus-containing group transferase (EC 2.7.*) inhibitors", "phosphorus-containing group transferase inhibitor", "phosphorus-containing group transferase inhibitors" ; oboInOwl:id "CHEBI:76668" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.7.* (P-containing group transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_71300 . obo:CHEBI_76710 obo:IAO_0000115 "An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation." ; oboInOwl:hasDbXref "Wikipedia:Lyase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 4.* (lyase) inhibitors", "EC 4.* inhibitor", "EC 4.* inhibitors", "EC 4.*.*.* inhibitor", "EC 4.*.*.* inhibitors", "lyase (EC 4.*) inhibitor", "lyase (EC 4.*) inhibitorS", "lyase inhibitor", "lyase inhibitors" ; oboInOwl:id "CHEBI:76710" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 4.* (lyase) inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_76713 obo:IAO_0000115 "A lyase inhibitor which inhibits the action of a C-N lyase (EC 4.3.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C-N lyase (EC 4.3.*) inhibitor", "C-N lyase (EC 4.3.*) inhibitors", "C-N lyase inhibitor", "C-N lyase inhibitors", "EC 4.3.* (C-N lyase) inhibitors", "EC 4.3.* inhibitor", "EC 4.3.* inhibitors" ; oboInOwl:id "CHEBI:76713" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 4.3.* (C-N lyase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76710 . obo:CHEBI_76725 obo:IAO_0000115 "An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*)." ; oboInOwl:hasDbXref "Wikipedia:Oxidoreductase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 1.* (oxidoreductase) inhibitors", "EC 1.* inhibitor", "EC 1.* inhibitors", "oxidoreductase (EC 1.*) inhibitor", "oxidoreductase (EC 1.*) inhibitors", "oxidoreductase inhibitor", "oxidoreductase inhibitors" ; oboInOwl:id "CHEBI:76725" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 1.* (oxidoreductase) inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_76744 obo:IAO_0000115 "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH2 (EC 1.17.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitors", "EC 1.17.* inhibitor", "EC 1.17.* inhibitors", "oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitor", "oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitors", "oxidoreductase acting on CH or CH2 inhibitor", "oxidoreductase acting on CH or CH2 inhibitors" ; oboInOwl:id "CHEBI:76744" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor" ; rdfs:subClassOf obo:CHEBI_76725 . obo:CHEBI_76759 obo:IAO_0000115 "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." ; oboInOwl:hasDbXref "Wikipedia:Hydrolase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.* (hydrolase) inhibitors", "EC 3.* inhibitor", "EC 3.* inhibitors", "EC 3.*.*.* inhibitor", "EC 3.*.*.* inhibitors", "hydrolase (EC 3.*) inhibitor", "hydrolase (EC 3.*) inhibitors", "hydrolase inhibitor", "hydrolase inhibitors" ; oboInOwl:id "CHEBI:76759" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.* (hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_76760 obo:IAO_0000115 "A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.* (ester hydrolase) inhibitors", "EC 3.1.* inhibitor", "EC 3.1.* inhibitors", "ester hydrolase (EC 3.1.*) inhibitor", "ester hydrolase (EC 3.1.*) inhibitors", "ester hydrolase inhibitor", "ester hydrolase inhibitors" ; oboInOwl:id "CHEBI:76760" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.1.* (ester hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76759 . obo:CHEBI_76764 obo:IAO_0000115 "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor", "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors", "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor", "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors", "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors", "EC 3.5.* inhibitor", "EC 3.5.* inhibitors" ; oboInOwl:id "CHEBI:76764" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor" ; rdfs:subClassOf obo:CHEBI_76759 . obo:CHEBI_76773 obo:IAO_0000115 "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.1.* (carboxylic ester hydrolase) inhibitors", "EC 3.1.1.* inhibitor", "EC 3.1.1.* inhibitors", "carboxylic ester hydrolase (EC 3.1.1.*) inhibitor", "carboxylic ester hydrolase (EC 3.1.1.*) inhibitors" ; oboInOwl:id "CHEBI:76773" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.1.1.* (carboxylic ester hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76760 . obo:CHEBI_76775 obo:IAO_0000115 "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors", "EC 3.1.3.* inhibitor", "EC 3.1.3.* inhibitors", "inhibitor of phosphoric monoester hydrolase", "inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*)", "inhibitors of phosphoric monoester hydrolase", "inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*)", "phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor", "phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors", "phosphoric monoester hydrolase inhibitor", "phosphoric monoester hydrolase inhibitors" ; oboInOwl:id "CHEBI:76775" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76760 . obo:CHEBI_76779 obo:IAO_0000115 "Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.4.21.26 (prolyl oligopeptidase) inhibitors", "EC 3.4.21.26 inhibitor", "EC 3.4.21.26 inhibitors", "endoprolylpeptidase inhibitor", "endoprolylpeptidase inhibitors", "post-proline cleaving enzyme inhibitor", "post-proline cleaving enzyme inhibitors", "post-proline endopeptidase inhibitor", "post-proline endopeptidase inhibitors", "proline endopeptidase inhibitor", "proline endopeptidase inhibitors", "proline-specific endopeptidase inhibitor", "proline-specific endopeptidase inhibitors", "prolyl endopeptidase inhibitor", "prolyl endopeptidase inhibitors", "prolyl oligopeptidase (EC 3.4.21.26) inhibitor", "prolyl oligopeptidase (EC 3.4.21.26) inhibitors", "prolyl oligopeptidase inhibitor" ; oboInOwl:id "CHEBI:76779" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.4.21.26 (prolyl oligopeptidase) inhibitor" ; rdfs:subClassOf obo:CHEBI_5924 . obo:CHEBI_76797 obo:IAO_0000115 "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18)." ; oboInOwl:hasDbXref "Wikipedia:Glutathione_S-transferase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.5.1.18 (glutathione transferase) inhibitors", "EC 2.5.1.18 inhibitor", "EC 2.5.1.18 inhibitors", "RX:glutathione R-transferase inhibitor", "RX:glutathione R-transferase inhibitors", "S-(hydroxyalkyl)glutathione lyase inhibitor", "S-(hydroxyalkyl)glutathione lyase inhibitors", "glutathione S-alkyl transferase inhibitor", "glutathione S-alkyl transferase inhibitors", "glutathione S-alkyltransferase inhibitor", "glutathione S-alkyltransferase inhibitors", "glutathione S-aralkyltransferase inhibitor", "glutathione S-aralkyltransferase inhibitors", "glutathione S-aryltransferase inhibitor", "glutathione S-aryltransferase inhibitors", "glutathione S-transferase inhibitor", "glutathione S-transferase inhibitors", "glutathione transferase (EC 2.5.1.18) inhibitor", "glutathione transferase (EC 2.5.1.18) inhibitors", "glutathione transferase inhibitor", "glutathione transferase inhibitors" ; oboInOwl:id "CHEBI:76797" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.5.1.18 (glutathione transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76663 . obo:CHEBI_76807 obo:IAO_0000115 "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors", "EC 3.5.1.* inhibitor", "EC 3.5.1.* inhibitors", "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor", "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors" ; oboInOwl:id "CHEBI:76807" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76764 . obo:CHEBI_76812 obo:IAO_0000115 "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.11.* (protein-serine/threonine kinase) inhibitors", "EC 2.7.11.* inhibitor", "EC 2.7.11.* inhibitors", "protein-serine/threonine kinase (EC 2.7.11.*) inhibitor", "protein-serine/threonine kinase (EC 2.7.11.*) inhibitors", "protein-serine/threonine kinase inhibitor", "protein-serine/threonine kinase inhibitors" ; oboInOwl:id "CHEBI:76812" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.7.11.* (protein-serine/threonine kinase) inhibitor" ; rdfs:subClassOf obo:CHEBI_37699 . obo:CHEBI_76815 obo:IAO_0000115 "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.7.* (nucleotidyltransferase) inhibitors", "inhibitor of nucleotidyltransferases", "inhibitor of nucleotidyltransferases (EC 2.7.7.*)", "inhibitors of nucleotidyltransferases", "inhibitors of nucleotidyltransferases (EC 2.7.7.*)", "nucleotidyltransferase (EC 2.7.7.*) inhibitor", "nucleotidyltransferase (EC 2.7.7.*) inhibitors", "nucleotidyltransferase inhibitor", "nucleotidyltransferase inhibitors" ; oboInOwl:id "CHEBI:76815" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.7.7.* (nucleotidyltransferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76668 . obo:CHEBI_76816 obo:IAO_0000115 "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitors", "EC 2.7.8.* inhibitor", "EC 2.7.8.* inhibitors" ; oboInOwl:id "CHEBI:76816" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor" ; rdfs:subClassOf obo:CHEBI_76668 . obo:CHEBI_76832 obo:IAO_0000115 "An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 4.3.1.* (ammonia-lyase) inhibitors", "EC 4.3.1.* (ammonia-lyases) inhibitor", "EC 4.3.1.* (ammonia-lyases) inhibitors", "EC 4.3.1.* inhibitor", "EC 4.3.1.* inhibitors", "ammonia-lyase (EC 4.3.1.*) inhibitor", "ammonia-lyase (EC 4.3.1.*) inhibitors", "ammonia-lyase inhibitor", "ammonia-lyase inhibitors" ; oboInOwl:id "CHEBI:76832" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 4.3.1.* (ammonia-lyase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76713 . obo:CHEBI_76834 obo:IAO_0000115 "An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitors", "EC 2.5.* inhibitor", "EC 2.5.* inhibitors", "non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitor", "non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitors" ; oboInOwl:id "CHEBI:76834" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_71300 . obo:CHEBI_76848 obo:IAO_0000115 "An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitors", "EC 1.17.4.* inhibitor", "EC 1.17.4.* inhibitors", "oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitor", "oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitors" ; oboInOwl:id "CHEBI:76848" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor" ; rdfs:subClassOf obo:CHEBI_76744 . obo:CHEBI_76895 obo:IAO_0000115 "An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitors", "EC 3.6.3.* inhibitor", "EC 3.6.3.* inhibitors", "acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitor", "acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitors" ; oboInOwl:id "CHEBI:76895" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor" ; rdfs:subClassOf obo:CHEBI_73216 . obo:CHEBI_76924 obo:IAO_0000115 "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." ; oboInOwl:hasAlternativeId "CHEBI:75766", "CHEBI:76925" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "plant metabolites", "plant secondary metabolites" ; oboInOwl:id "CHEBI:76924" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "plant metabolite" ; rdfs:subClassOf obo:CHEBI_75763 . obo:CHEBI_76932 obo:IAO_0000115 "An enzyme inhibitor that interferes with one or more steps in a metabolic pathway." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metabolic pathway inhibitor", "metabolic pathway inhibitors", "pathway inhibitors" ; oboInOwl:id "CHEBI:76932" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pathway inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_76946 obo:IAO_0000115 "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." ; oboInOwl:hasAlternativeId "CHEBI:75765", "CHEBI:76947" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fungal metabolites" ; oboInOwl:id "CHEBI:76946" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fungal metabolite" ; rdfs:subClassOf obo:CHEBI_75763 . obo:CHEBI_76967 obo:IAO_0000115 "Any human metabolite produced by metabolism of a xenobiotic compound in humans." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "human xenobiotic metabolites" ; oboInOwl:id "CHEBI:76967" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "human xenobiotic metabolite" ; rdfs:subClassOf obo:CHEBI_76206, obo:CHEBI_77746 . obo:CHEBI_76969 obo:IAO_0000115 "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." ; oboInOwl:hasAlternativeId "CHEBI:75760", "CHEBI:76970" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:76969" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bacterial metabolite" ; rdfs:subClassOf obo:CHEBI_75787 . obo:CHEBI_76971 obo:IAO_0000115 "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "E.coli metabolite", "E.coli metabolites", "Escherichia coli metabolites" ; oboInOwl:id "CHEBI:76971" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "Escherichia coli metabolite" ; rdfs:subClassOf obo:CHEBI_76969 . obo:CHEBI_76976 obo:IAO_0000115 "Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bacterial xenobiotic metabolites" ; oboInOwl:id "CHEBI:76976" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "bacterial xenobiotic metabolite" ; rdfs:subClassOf obo:CHEBI_76206, obo:CHEBI_76969 . obo:CHEBI_76988 obo:IAO_0000115 "A synthetic or semi-synthetic compound that has oestrogenic activity." ; oboInOwl:hasDbXref "Wikipedia:Xenoestrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "xenoestrogens" ; oboInOwl:id "CHEBI:76988" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "xenoestrogen" ; rdfs:subClassOf obo:CHEBI_138015, obo:CHEBI_50114 . obo:CHEBI_77022 obo:IAO_0000115 "An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of an acyltransferase which converts the acyl group to an alkyl group on transfer (EC 2.3.3.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitors", "EC 2.3.3.* inhibitor", "EC 2.3.3.* inhibitors", "acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitor", "acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitors" ; oboInOwl:id "CHEBI:77022" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor" ; rdfs:subClassOf obo:CHEBI_76661 . obo:CHEBI_77023 obo:IAO_0000115 "An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of citrate (Si)-synthase, EC 2.3.3.1." ; oboInOwl:hasDbXref "Wikipedia:Citrate_synthase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(R)-citrate synthase inhibitor", "(R)-citrate synthase inhibitors", "EC 2.3.3.1 (citrate (Si)-synthase) inhibitor", "EC 2.3.3.1 (citrate (Si)-synthase) inhibitors", "EC 2.3.3.1 [citrate (Si)-synthase] inhibitors", "EC 2.3.3.1 inhibitor", "EC 2.3.3.1 inhibitors", "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitor", "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitors", "citrate (Si)-synthase (EC 2.3.3.1) inhibitor", "citrate (Si)-synthase (EC 2.3.3.1) inhibitors", "citrate condensing enzyme inhibitor", "citrate condensing enzyme inhibitors", "citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitor", "citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitors", "citrate oxaloacetate-lyase, CoA-acetylating inhibitor", "citrate oxaloacetate-lyase, CoA-acetylating inhibitors", "citrate synthase inhibitor", "citrate synthase inhibitors", "citrate synthetase inhibitor", "citrate synthetase inhibitors", "citric synthase inhibitor", "citric synthase inhibitors", "citric-condensing enzyme inhibitor", "citric-condensing enzyme inhibitors", "citrogenase inhibitor", "citrogenase inhibitors", "condensing enzyme inhibitor", "condensing enzyme inhibitors", "oxalacetic transacetase inhibitor", "oxalacetic transacetase inhibitors", "oxaloacetate transacetase inhibitor", "oxaloacetate transacetase inhibitors" ; oboInOwl:id "CHEBI:77023" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 2.3.3.1 [citrate (Si)-synthase] inhibitor" ; rdfs:subClassOf obo:CHEBI_77022 . obo:CHEBI_77024 obo:IAO_0000115 "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41)." ; oboInOwl:hasDbXref "Wikipedia:4-nitrophenylphosphatase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-nitrophenylphosphatase (EC 3.1.3.41) inhibitor", "4-nitrophenylphosphatase (EC 3.1.3.41) inhibitors", "4-nitrophenylphosphate phosphohydrolase inhibitor", "4-nitrophenylphosphate phosphohydrolase inhibitors", "EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitors", "EC 3.1.3.41 inhibitor", "EC 3.1.3.41 inhibitors", "Ecto-p-nitrophenyl phosphatase inhibitor", "Ecto-p-nitrophenyl phosphatase inhibitors", "K-pNPPase inhibitor", "K-pNPPase inhibitors", "NPPase inhibitor", "NPPase inhibitors", "PNPPase inhibitor", "PNPPase inhibitors", "nitrophenyl phosphatase inhibitor", "nitrophenyl phosphatase inhibitors", "p-nitrophenylphosphatase inhibitor", "p-nitrophenylphosphatase inhibitors", "p-nitrophenylphosphate phosphohydrolase inhibitor", "p-nitrophenylphosphate phosphohydrolase inhibitors", "para-nitrophenyl phosphatase inhibitor", "para-nitrophenyl phosphatase inhibitors", "xK-pNPPase inhibitors" ; oboInOwl:id "CHEBI:77024" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76775 . obo:CHEBI_77035 obo:IAO_0000115 "Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex." ; oboInOwl:hasDbXref "PMID:17594730" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "expectorants" ; oboInOwl:id "CHEBI:77035" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "expectorant" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_77278 obo:IAO_0000115 "An imidazothiazole that is imidazo[2,1-b][1,3]thiazole in which the double bonds at the 2-3 and 5-6 positions have been reduced to single bonds and in which one of the hydrogens at position 6 is replaced by a phenyl group." ; chebi:charge "0" ; chebi:formula "C11H12N2S" ; chebi:inchi "InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2" ; chebi:inchikey "HLFSDGLLUJUHTE-UHFFFAOYSA-N" ; chebi:mass "204.29100" ; chebi:monoisotopicmass "204.07212" ; chebi:smiles "C1CN2CC(N=C2S1)c1ccccc1" ; oboInOwl:hasDbXref "LINCS:LSM-1579" ; oboInOwl:hasExactSynonym "6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:77278" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole" ; rdfs:subClassOf obo:CHEBI_48909, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ] . obo:CHEBI_77282 obo:IAO_0000115 "A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has R configuration." ; chebi:charge "0" ; chebi:formula "C11H12N2S" ; chebi:inchi "InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m0/s1" ; chebi:inchikey "HLFSDGLLUJUHTE-JTQLQIEISA-N" ; chebi:mass "204.29100" ; chebi:monoisotopicmass "204.07212" ; chebi:smiles "C1CN2C[C@H](N=C2S1)c1ccccc1" ; oboInOwl:hasDbXref "CAS:14769-74-5", "KEGG:D03708", "PMID:189006", "PMID:22337783", "PMID:669135", "PMID:7454609", "Reaxys:5267119" ; oboInOwl:hasExactSynonym "(6R)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole", "(+)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole", "(+)-tetramisole", "(R)-(+)-tetramisole", "dexamisol", "dexamisole", "dexamisolum" ; oboInOwl:id "CHEBI:77282" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "dexamisole" ; rdfs:subClassOf obo:CHEBI_77278, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_6432 ] . obo:CHEBI_77307 obo:IAO_0000115 "Any protective agent that is able to prevent damage to the heart." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cardioprotective agents" ; oboInOwl:id "CHEBI:77307" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cardioprotective agent" ; rdfs:subClassOf obo:CHEBI_50267 . obo:CHEBI_77703 obo:IAO_0000115 "An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3)." ; oboInOwl:hasDbXref "Wikipedia:Histidine_ammonia-lyase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 4.3.1.3 (histidine ammonia-lyase) inhibitors", "EC 4.3.1.3 inhibitor", "EC 4.3.1.3 inhibitors", "L-histidine ammonia-lyase (urocanate-forming) inhibitor", "L-histidine ammonia-lyase (urocanate-forming) inhibitors", "L-histidine ammonia-lyase inhibitor", "L-histidine ammonia-lyase inhibitors", "histidase inhibitor", "histidase inhibitors", "histidinase inhibitor", "histidinase inhibitors", "histidine alpha-deaminase inhibitor", "histidine alpha-deaminase inhibitors", "histidine ammonia-lyase (EC 4.3.1.3) inhibitor", "histidine ammonia-lyase (EC 4.3.1.3) inhibitors", "histidine ammonia-lyase inhibitor", "histidine ammonia-lyase inhibitors" ; oboInOwl:id "CHEBI:77703" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 4.3.1.3 (histidine ammonia-lyase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76832 . obo:CHEBI_77746 obo:IAO_0000115 "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." ; oboInOwl:hasAlternativeId "CHEBI:75770", "CHEBI:77123" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H. sapiens metabolite", "H. sapiens metabolites", "Homo sapiens metabolite", "Homo sapiens metabolites" ; oboInOwl:id "CHEBI:77746" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "human metabolite" ; rdfs:subClassOf obo:CHEBI_75768 . obo:CHEBI_77941 obo:IAO_0000115 "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." ; oboInOwl:hasDbXref "Wikipedia:Amidase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.5.1.4 (amidase) inhibitors", "EC 3.5.1.4 inhibitor", "EC 3.5.1.4 inhibitors", "N-acetylaminohydrolase inhibitor", "N-acetylaminohydrolase inhibitors", "acylamidase inhibitor", "acylamidase inhibitors", "acylamide amidohydrolase inhibitor", "acylamide amidohydrolase inhibitors", "amidase (EC 3.5.1.4) inhibitor", "amidase (EC 3.5.1.4) inhibitors", "amidase inhibitor", "amidase inhibitors", "amidohydrolase inhibitor", "amidohydrolase inhibitors", "deaminase inhibitor", "deaminase inhibitors", "fatty acylamidase inhibitor", "fatty acylamidase inhibitors" ; oboInOwl:id "CHEBI:77941" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "EC 3.5.1.4 (amidase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76807 . obo:CHEBI_77974 obo:IAO_0000115 "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." ; oboInOwl:hasDbXref "Wikipedia:Packaging_gas" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food packaging gases" ; oboInOwl:id "CHEBI:77974" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "food packaging gas" ; rdfs:subClassOf obo:CHEBI_64047 . obo:CHEBI_78017 obo:IAO_0000115 "A propellant that is used to expel foods from an aerosol container." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food propellants" ; oboInOwl:id "CHEBI:78017" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "food propellant" ; rdfs:subClassOf obo:CHEBI_64047, obo:CHEBI_76414 . obo:CHEBI_78115 obo:IAO_0000115 "Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C4H7O2" ; chebi:mass "87.09718" ; chebi:monoisotopicmass "87.04460" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fatty acid 4:0" ; oboInOwl:id "CHEBI:78115" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fatty acid anion 4:0" ; rdfs:subClassOf obo:CHEBI_58951, obo:CHEBI_58953, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_140601 ] . obo:CHEBI_78116 obo:IAO_0000115 "Any saturated fatty acid anion containing 6 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C6H11O2" ; chebi:mass "115.15034" ; chebi:monoisotopicmass "115.07590" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fatty acid 6:0" ; oboInOwl:id "CHEBI:78116" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fatty acid anion 6:0" ; rdfs:subClassOf obo:CHEBI_58953, obo:CHEBI_59558 . obo:CHEBI_78295 obo:IAO_0000115 "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dietary component", "dietary components", "food components" ; oboInOwl:id "CHEBI:78295" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "food component" ; rdfs:subClassOf obo:CHEBI_52211 . obo:CHEBI_78298 obo:IAO_0000115 "Any minor or unwanted substance introduced into the environment that can have undesired effects." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "environmental contaminants" ; oboInOwl:id "CHEBI:78298" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "environmental contaminant" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_78433 obo:IAO_0000115 "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." ; oboInOwl:hasDbXref "Wikipedia:Refrigerant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "refrigerants" ; oboInOwl:id "CHEBI:78433" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "refrigerant" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_78608 obo:IAO_0000115 "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "[NH3+]C([*])C([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:83409" ; oboInOwl:hasDbXref "MetaCyc:Alpha-Amino-Acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an alpha-amino acid" ; oboInOwl:id "CHEBI:78608" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha-amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi2:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_33704 ] . obo:CHEBI_78616 obo:IAO_0000115 "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrates and derivatives", "carbohydrates and their derivatives" ; oboInOwl:id "CHEBI:78616" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "carbohydrates and carbohydrate derivatives" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_78675 obo:IAO_0000115 "Any metabolite produced by all living cells." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "essential metabolite", "essential metabolites", "fundamental metabolites" ; oboInOwl:id "CHEBI:78675" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "fundamental metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_78840 obo:IAO_0000115 "Any organic molecular entity that contains at least one C=C bond." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "olefinic compounds" ; oboInOwl:id "CHEBI:78840" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "olefinic compound" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_79008 obo:IAO_0000115 "The conjugate acid of (R)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C10H15N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/p+1/t10-/m1/s1" ; chebi:inchikey "SNICXCGAKADSCV-SNVBAGLBSA-O" ; chebi:mass "163.23900" ; chebi:monoisotopicmass "163.12297" ; chebi:smiles "C[NH+]1CCC[C@@H]1c1cccnc1" ; oboInOwl:hasDbXref "MetaCyc:R-NICOTINE" ; oboInOwl:hasExactSynonym "(2R)-1-methyl-2-(pyridin-3-yl)pyrrolidinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(R)-nicotine" ; oboInOwl:id "CHEBI:79008" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(R)-nicotinium(1+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_39162 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_59806 ] . obo:CHEBI_79020 obo:IAO_0000115 "A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C#C bond." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,3-unsaturated monocarboxylic acid", "2,3-unsaturated monocarboxylic acids", "alpha,beta-unsaturated monocarboxylic acids" ; oboInOwl:id "CHEBI:79020" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "alpha,beta-unsaturated monocarboxylic acid" ; rdfs:subClassOf obo:CHEBI_25384 . obo:CHEBI_79314 obo:IAO_0000115 "Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire." ; oboInOwl:hasDbXref "Wikipedia:Flame_retardant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "flame retardants" ; oboInOwl:id "CHEBI:79314" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "flame retardant" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_79387 obo:IAO_0000115 "Any inorganic anion with a valency of three." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "trivalent inorganic anions" ; oboInOwl:id "CHEBI:79387" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "trivalent inorganic anion" ; rdfs:subClassOf obo:CHEBI_24834 . obo:CHEBI_79388 obo:IAO_0000115 "Any inorganic anion with a valency of two." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "divalent inorganic anions" ; oboInOwl:id "CHEBI:79388" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "divalent inorganic anion" ; rdfs:subClassOf obo:CHEBI_24834 . obo:CHEBI_79389 obo:IAO_0000115 "Any inorganic anion with a valency of one." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monovalent inorganic anions" ; oboInOwl:id "CHEBI:79389" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monovalent inorganic anion" ; rdfs:subClassOf obo:CHEBI_24834 . obo:CHEBI_8081 obo:IAO_0000115 "A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension." ; chebi:charge "0" ; chebi:formula "C17H19N3O" ; chebi:inchi "InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)" ; chebi:inchikey "MRBDMNSDAVCSSF-UHFFFAOYSA-N" ; chebi:mass "281.35230" ; chebi:monoisotopicmass "281.15281" ; chebi:smiles "Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1" ; oboInOwl:hasDbXref "CAS:50-60-2", "DrugBank:DB00692", "Drug_Central:2142", "HMDB:HMDB0014830", "KEGG:D00509", "KEGG:D08362", "LINCS:LSM-4022", "PMID:23438114", "PMID:23522530", "PMID:23658874", "PMID:23666670", "PMID:23887290", "PMID:23926134", "Patent:US2503059", "Reaxys:272944", "Wikipedia:Phentolamine" ; oboInOwl:hasExactSynonym "3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline", "Phentolamine mesylate", "Regitina", "Regitine", "Rogitine", "fentolamina", "phentolamine", "phentolaminum" ; oboInOwl:id "CHEBI:8081" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phentolamine" ; rdfs:subClassOf obo:CHEBI_24780, obo:CHEBI_33853, obo:CHEBI_48975, obo:CHEBI_50996, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37890 ] . obo:CHEBI_8116 obo:IAO_0000115 "A diterpenoid with the structure of tigliane hydroxylated at C-4, -9, -12(beta), -13 and -20, with an oxo group at C-3 and unsaturation at the 1- and 6-positions." ; chebi:charge "0" ; chebi:formula "C20H28O6" ; chebi:inchi "InChI=1S/C20H28O6/c1-9-5-13-18(24,15(9)22)7-11(8-21)6-12-14-17(3,4)20(14,26)16(23)10(2)19(12,13)25/h5-6,10,12-14,16,21,23-26H,7-8H2,1-4H3/t10-,12+,13-,14-,16-,18-,19-,20-/m1/s1" ; chebi:inchikey "QGVLYPPODPLXMB-UBTYZVCOSA-N" ; chebi:mass "364.433" ; chebi:monoisotopicmass "364.18859" ; chebi:smiles "C=1[C@@]2([C@@]([C@]3([C@@](C(=O)C(=C3)C)(CC1CO)O)[H])([C@H](C)[C@H]([C@@]4([C@]2(C4(C)C)[H])O)O)O)[H]" ; oboInOwl:hasDbXref "Beilstein:2341335", "CAS:17673-25-5", "KEGG:C09155", "KNApSAcK:C00003465", "LIPID_MAPS_instance:LMPR0104330001", "PMID:27007853" ; oboInOwl:hasExactSynonym "(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-5H-cyclopropa[3,4]benzo[1,2-e]azulen-5-one", "Phorbol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4,9,12beta,13,20-pentahydroxy-1,6-tigliadien-3-on", "4,9,12beta,13,20-pentahydroxytiglia-1,6-dien-3-one" ; oboInOwl:id "CHEBI:8116" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "phorbol" ; rdfs:subClassOf obo:CHEBI_139592, obo:CHEBI_3992, obo:CHEBI_51689, obo:CHEBI_52557, [ a owl:Restriction ; owl:onProperty chebi2:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_37526 ] . obo:CHEBI_82680 obo:IAO_0000115 "Any unsaturated fatty acid anion with one double or triple bond in the fatty acid chain." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monounsaturated fatty acid anions" ; oboInOwl:id "CHEBI:82680" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "monounsaturated fatty acid anion" ; rdfs:subClassOf obo:CHEBI_2580, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_25413 ] . obo:CHEBI_82744 obo:IAO_0000115 "Any aldoxime derived from an aliphatic aldehyde." ; chebi:charge "0" ; chebi:formula "CH2NOR" ; chebi:mass "44.03270" ; chebi:monoisotopicmass "44.01364" ; chebi:smiles "ON=C[*]" ; oboInOwl:hasDbXref "MetaCyc:Aliphatic-Aldoximes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an aliphatic aldoxime" ; oboInOwl:id "CHEBI:82744" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "aliphatic aldoxime" ; rdfs:subClassOf obo:CHEBI_22307 . obo:CHEBI_83039 obo:IAO_0000115 "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "crustacean metabolites" ; oboInOwl:id "CHEBI:83039" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "crustacean metabolite" ; rdfs:subClassOf obo:CHEBI_75767 . obo:CHEBI_83056 obo:IAO_0000115 "A Daphnia metabolite produced by the species Daphnia magna." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Daphnia magna metabolites" ; oboInOwl:id "CHEBI:83056" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "Daphnia magna metabolite" ; rdfs:subClassOf obo:CHEBI_83057 . obo:CHEBI_83057 obo:IAO_0000115 "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" ; oboInOwl:hasDbXref "Wikipedia:Daphnia" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Daphnia metabolites" ; oboInOwl:id "CHEBI:83057" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "Daphnia metabolite" ; rdfs:subClassOf obo:CHEBI_83039 . obo:CHEBI_83347 obo:IAO_0000115 "An ester resulting from the formal condensation of the hydroxy group of an alcohol, phenol, heteroarenol, or enol with an organosulfonic acid." ; chebi:charge "0" ; chebi:formula "O3SR2" ; chebi:mass "80.06300" ; chebi:monoisotopicmass "79.95681" ; chebi:smiles "[*]S(=O)(=O)O[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organosulfonate ester", "organosulfonate esters", "organosulfonic esters" ; oboInOwl:id "CHEBI:83347" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "organosulfonic ester" ; rdfs:subClassOf obo:CHEBI_33424, obo:CHEBI_35701, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33551 ] . obo:CHEBI_83399 obo:IAO_0000115 "Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "marine xenobiotic metabolites" ; oboInOwl:id "CHEBI:83399" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "marine xenobiotic metabolite" ; rdfs:subClassOf obo:CHEBI_76206, obo:CHEBI_76507 . obo:CHEBI_83565 obo:IAO_0000115 "An organofluorine compound that is (trifluoromethyl)benzene and derivatives arising from substitution of one or more of the phenyl hydrogens." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:83565" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(trifluoromethyl)benzenes" ; rdfs:subClassOf obo:CHEBI_22712, obo:CHEBI_37143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50127 ] . obo:CHEBI_83811 obo:IAO_0000115 "Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical amino acid derivative", "canonical amino acid derivatives", "canonical amino-acid derivative", "canonical amino-acid derivatives", "proteinogenic amino acid derivatives", "proteinogenic amino-acid derivative", "proteinogenic amino-acid derivatives" ; oboInOwl:id "CHEBI:83811" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "proteinogenic amino acid derivative" ; rdfs:subClassOf obo:CHEBI_83821, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_83813 ] . obo:CHEBI_83813 obo:IAO_0000115 "Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration." ; oboInOwl:hasDbXref "Wikipedia:Proteinogenic_amino_acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical amino acid", "canonical amino acids", "proteinogenic amino acids" ; oboInOwl:id "CHEBI:83813" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "proteinogenic amino acid" ; rdfs:subClassOf obo:CHEBI_33575, obo:CHEBI_35352 . obo:CHEBI_83820 obo:IAO_0000115 "Any amino-acid that is not naturally encoded in the genetic code of any organism." ; oboInOwl:hasDbXref "Wikipedia:Non-proteinogenic_amino_acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "non-canonical amino acid", "non-canonical amino acids", "non-canonical amino-acid", "non-canonical amino-acids", "non-coded amino acid", "non-coded amino acids", "non-coded amino-acid", "non-coded amino-acids", "non-proteinogenic amino acids", "non-proteinogenic amino-acid", "non-proteinogenic amino-acids" ; oboInOwl:id "CHEBI:83820" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "non-proteinogenic amino acid" ; rdfs:subClassOf obo:CHEBI_33709 . obo:CHEBI_83821 obo:IAO_0000115 "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues." ; oboInOwl:hasAlternativeId "CHEBI:25359" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino acid derivatives", "modified amino acids" ; oboInOwl:id "CHEBI:83821" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "amino acid derivative" ; rdfs:subClassOf obo:CHEBI_35352 . obo:CHEBI_83824 obo:IAO_0000115 "A proteinogenic amino acid derivative resulting from the formal reaction of L-cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of L-cysteine by a heteroatom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-cysteine derivatives" ; oboInOwl:id "CHEBI:83824" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "L-cysteine derivative" ; rdfs:subClassOf obo:CHEBI_23509, obo:CHEBI_83811, [ a owl:Restriction ; owl:onProperty chebi2:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17561 ] . obo:CHEBI_83925 obo:IAO_0000115 "Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "non-proteinogenic alpha-amino acids", "non-proteinogenic alpha-amino-acid", "non-proteinogenic alpha-amino-acids" ; oboInOwl:id "CHEBI:83925" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "non-proteinogenic alpha-amino acid" ; rdfs:subClassOf obo:CHEBI_33704, obo:CHEBI_83820 . obo:CHEBI_83970 obo:IAO_0000115 "Steroid lactones containing sugar residues that act on the contractile force of the cardiac muscles." ; oboInOwl:hasDbXref "Wikipedia:Cardiac_glycoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cardiac glycosides" ; oboInOwl:id "CHEBI:83970" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "cardiac glycoside" ; rdfs:subClassOf obo:CHEBI_24400, obo:CHEBI_26766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77307 ] . obo:CHEBI_84055 obo:IAO_0000115 "Any phospho sugar that is the phosphate derivative of pentose." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pentose phosphates" ; oboInOwl:id "CHEBI:84055" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "pentose phosphate" ; rdfs:subClassOf obo:CHEBI_33447, obo:CHEBI_63409 . obo:CHEBI_84087 obo:IAO_0000115 "Any metabolite (endogenous or exogenous) found in human urine samples." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "human urinary metabolites" ; oboInOwl:id "CHEBI:84087" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "human urinary metabolite" ; rdfs:subClassOf obo:CHEBI_77746 . obo:CHEBI_84729 obo:IAO_0000115 "Any member of the class of indoles carrying at least one hydroxy group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:84729" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "hydroxyindoles" ; rdfs:subClassOf obo:CHEBI_24828, obo:CHEBI_33822 . obo:CHEBI_84735 obo:IAO_0000115 "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "algal metabolites" ; oboInOwl:id "CHEBI:84735" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "algal metabolite" ; rdfs:subClassOf obo:CHEBI_75763 . obo:CHEBI_85046 obo:IAO_0000115 "Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin." ; oboInOwl:hasDbXref "PMID:21265866", "PMID:22132817", "PMID:22314516", "PMID:23891889", "PMID:23974587", "PMID:25535470", "PMID:25574195", "PMID:25643794", "Wikipedia:Skin_whitening" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "melanogenesis inhibitor", "melanogenesis inhibitors", "skin bleaching agent", "skin bleaching agents", "skin depigmenting agent", "skin depigmenting agents", "skin lightening agents", "skin whitening agent", "skin whitening agents" ; oboInOwl:id "CHEBI:85046" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "skin lightening agent" ; rdfs:subClassOf obo:CHEBI_64857 . obo:CHEBI_85234 obo:IAO_0000115 "Any metabolite (endogenous or exogenous) found in human blood serum samples." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "human blood serum metabolites" ; oboInOwl:id "CHEBI:85234" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "human blood serum metabolite" ; rdfs:subClassOf obo:CHEBI_77746 . obo:CHEBI_86315 obo:IAO_0000115 "Any aliphatic sulfide in which at least one of the organyl groups attached to the sulfur is a methyl group." ; chebi:charge "0" ; chebi:formula "CH3SR" ; chebi:mass "47.101" ; chebi:monoisotopicmass "46.99555" ; chebi:smiles "CS[*]" ; oboInOwl:hasAlternativeId "CHEBI:25260" ; oboInOwl:hasDbXref "MetaCyc:Methyl-thioethers" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a methyl thioether", "methyl sulfides", "methyl thioether", "methyl thioethers" ; oboInOwl:id "CHEBI:86315" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "methyl sulfide" ; rdfs:subClassOf obo:CHEBI_16385 . obo:CHEBI_86990 obo:IAO_0000115 "An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group." ; chebi:charge "0" ; chebi:formula "C17H18F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3" ; chebi:inchikey "RTHCYVBBDHJXIQ-UHFFFAOYSA-N" ; chebi:mass "309.32610" ; chebi:monoisotopicmass "309.13405" ; chebi:smiles "CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "LINCS:LSM-1449", "VSDB:1851" ; oboInOwl:hasExactSynonym "N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:86990" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; rdfs:subClassOf obo:CHEBI_35618, obo:CHEBI_50995, obo:CHEBI_83565 . obo:CHEBI_86991 obo:IAO_0000115 "An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has R configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine]." ; chebi:charge "0" ; chebi:formula "C17H18F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/t16-/m1/s1" ; chebi:inchikey "RTHCYVBBDHJXIQ-MRXNPFEDSA-N" ; chebi:mass "309.32610" ; chebi:monoisotopicmass "309.13405" ; chebi:smiles "CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "CAS:100568-03-4", "PMID:19144769", "PMID:19788198", "PMID:20663810", "PMID:22903652", "PMID:22923967", "PMID:23885544", "PMID:24464553", "PMID:24997906", "Reaxys:4356432" ; oboInOwl:hasExactSynonym "(3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-fluoxetine", "(R)-(+)-fluoxetine", "(R)-N-methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine", "(R)-N-methyl-3-(4-trifluoromethylphenyloxy)-3-(phenyl)propylamine", "(R)-N-methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy]propylamine", "(R)-N-methyl-gamma-(4-trifluoromethylphenoxy)-3-phenylpropylamine", "(R)-Prozac" ; oboInOwl:id "CHEBI:86991" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(R)-fluoxetine" ; rdfs:subClassOf obo:CHEBI_86990, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50949 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_86993 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_86992 ] . obo:CHEBI_86992 obo:IAO_0000115 "An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine]." ; chebi:charge "0" ; chebi:formula "C17H18F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/t16-/m0/s1" ; chebi:inchikey "RTHCYVBBDHJXIQ-INIZCTEOSA-N" ; chebi:mass "309.32610" ; chebi:monoisotopicmass "309.13405" ; chebi:smiles "CNCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "PMID:19144769", "PMID:19788198", "PMID:20663810", "PMID:22903652", "PMID:22923967", "PMID:23885544", "PMID:24464553", "PMID:24997906", "Reaxys:4356433" ; oboInOwl:hasExactSynonym "(3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-fluoxetine", "(S)-(-)-fluoxetine", "(S)-N-methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine", "(S)-N-methyl-3-(4-trifluoromethylphenyloxy)-3-(phenyl)propylamine", "(S)-N-methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy]propylamine", "(S)-N-methyl-gamma-(4-trifluoromethylphenoxy)-3-phenylpropylamine", "(S)-Prozac" ; oboInOwl:id "CHEBI:86992" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(S)-fluoxetine" ; rdfs:subClassOf obo:CHEBI_86990, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50949 ], [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_86995 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_86991 ] . obo:CHEBI_86993 obo:IAO_0000115 "An organic cation resulting from the protonation of the amino group of (R)-fluoxetine." ; chebi:charge "+1" ; chebi:formula "C17H19F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/p+1/t16-/m1/s1" ; chebi:inchikey "RTHCYVBBDHJXIQ-MRXNPFEDSA-O" ; chebi:mass "310.33350" ; chebi:monoisotopicmass "310.14133" ; chebi:smiles "C[NH2+]CC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "Reaxys:25263171" ; oboInOwl:hasExactSynonym "(3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-fluoxetine(1+)" ; oboInOwl:id "CHEBI:86993" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(R)-fluoxetine(1+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_86991 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_86995 ] . obo:CHEBI_86995 obo:IAO_0000115 "An organic cation resulting from the protonation of the amino group of (S)-fluoxetine." ; chebi:charge "+1" ; chebi:formula "C17H19F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/p+1/t16-/m0/s1" ; chebi:inchikey "RTHCYVBBDHJXIQ-INIZCTEOSA-O" ; chebi:mass "310.33350" ; chebi:monoisotopicmass "310.14133" ; chebi:smiles "C[NH2+]CC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "Reaxys:25263174" ; oboInOwl:hasExactSynonym "(3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-fluoxetine(1+)" ; oboInOwl:id "CHEBI:86995" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "(S)-fluoxetine(1+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi2:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_86992 ], [ a owl:Restriction ; owl:onProperty chebi2:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_86993 ] . obo:CHEBI_88184 obo:IAO_0000115 "Any metal which causes the onset of an allergic reaction." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "allergenic metal", "allergenic metals", "metal allergens" ; oboInOwl:id "CHEBI:88184" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "metal allergen" ; rdfs:subClassOf obo:CHEBI_33521, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50904 ] . obo:CHEBI_88188 obo:IAO_0000115 "Any drug which causes the onset of an allergic reaction." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "allergenic drug" ; oboInOwl:id "CHEBI:88188" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "drug allergen" ; rdfs:subClassOf obo:CHEBI_23888, obo:CHEBI_50904 . obo:CHEBI_88230 obo:IAO_0000115 "Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell)." ; oboInOwl:hasDbXref "PMID:24830781", "PMID:25727221", "PMID:25793774", "PMID:25896709", "Wikipedia:Autophagy" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "autophagocytosis inhibitor", "autophagocytosis inhibitors", "autophagy inhibitors" ; oboInOwl:id "CHEBI:88230" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "autophagy inhibitor" ; rdfs:subClassOf obo:CHEBI_35222, obo:CHEBI_52206 . obo:CHEBI_90710 obo:IAO_0000115 "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "receptor modulators" ; oboInOwl:id "CHEBI:90710" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "receptor modulator" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_9727 obo:IAO_0000115 "An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent." ; chebi:charge "0" ; chebi:formula "C6H9NO3" ; chebi:inchi "InChI=1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3" ; chebi:inchikey "IRYJRGCIQBGHIV-UHFFFAOYSA-N" ; chebi:mass "143.142" ; chebi:monoisotopicmass "143.05824" ; chebi:smiles "CN1C(=O)OC(C)(C)C1=O" ; oboInOwl:hasAlternativeId "CHEBI:94526" ; oboInOwl:hasDbXref "CAS:127-48-0", "DrugBank:DB00347", "Drug_Central:2751", "HMDB:HMDB0014491", "KEGG:D00392", "LINCS:LSM-5345", "PMID:10634315", "PMID:11057156", "PMID:11722678", "PMID:13590839", "PMID:13649111", "PMID:15282739", "PMID:15653505", "PMID:16171802", "PMID:18248662", "PMID:18862627", "PMID:18876072", "PMID:21638752", "PMID:2210093", "PMID:23017458", "PMID:23321016", "PMID:30605901", "PMID:7653500", "PMID:8791774", "PMID:8865369", "PMID:9375358", "PMID:9827046", "Reaxys:121627", "Wikipedia:Trimethadione" ; oboInOwl:hasExactSynonym "3,5,5-trimethyl-1,3-oxazolidine-2,4-dione" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3,5,5-trimethyl-2,4-oxazolidinedione", "Absentol", "Absetil", "Convenixa", "Edion", "Epidione", "Epixal", "Petidion", "Petilep", "Petimalin", "Ptimal", "Tridione", "Tridione Dulcet", "trimetadiona", "trimetadione", "trimethadione", "trimethadionum" ; oboInOwl:id "CHEBI:9727" ; oboInOwl:inSubset chebi5:_STAR ; a owl:Class ; rdfs:label "trimethadione" ; rdfs:subClassOf obo:CHEBI_55374, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35623 ] . obo:CL_0000000 obo:IAO_0000115 "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ; oboInOwl:hasDbXref "CALOHA:TS-2035", "FBbt:00007002", "FMA:68646", "GO:0005623", "KUPO:0000002", "MESH:D002477", "VHOG:0001533", "WBbt:0004017", "XAO:0003012" ; oboInOwl:inSubset ubprop:_upper_level ; a owl:Class ; rdfs:comment "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ; rdfs:label "cell" ; rdfs:subClassOf obo:UBERON_0000061, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_131567 ] ; owl:disjointWith obo:GO_0031012, obo:GO_0032991, obo:GO_0043226 . obo:CL_0000003 obo:IAO_0000115 "A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment)." ; oboInOwl:hasDbXref "CARO:0000013" ; oboInOwl:hasNarrowSynonym "cell in vivo" ; oboInOwl:inSubset ubprop:_upper_level ; a owl:Class ; rdfs:comment "To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12)." ; rdfs:label "native cell" ; rdfs:subClassOf obo:CL_0000000 . obo:CL_0000005 obo:IAO_0000115 "Any fibroblast that is deriived from the neural crest." ; a owl:Class ; rdfs:label "fibroblast neural crest derived" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000333 ] ) ] . obo:CL_0000006 oboInOwl:hasExactSynonym "neuronal receptor cell (sensu Animalia)" ; a owl:Class ; rdfs:label "neuronal receptor cell" ; rdfs:subClassOf obo:CL_0000101, obo:CL_0000197 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000197 obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0050906 ] ) ] . obo:CL_0000007 obo:IAO_0000115 "A cell found in the embryo before the formation of all the gem layers is complete." ; a owl:Class ; rdfs:label "early embryonic cell (metazoa)" ; rdfs:subClassOf obo:CL_0002321 . obo:CL_0000008 obo:IAO_0000115 "Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination." ; a owl:Class ; rdfs:label "migratory cranial neural crest cell" ; rdfs:subClassOf obo:CL_0000333 . obo:CL_0000011 obo:IAO_0000115 "Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination." ; a owl:Class ; rdfs:label "migratory trunk neural crest cell" ; rdfs:subClassOf obo:CL_0000333 . obo:CL_0000014 obo:IAO_0000115 "A stem cell that is the precursor of gametes." ; oboInOwl:hasExactSynonym "germline stem cell" ; a owl:Class ; rdfs:label "germ line stem cell" ; rdfs:subClassOf obo:CL_0000034, obo:CL_0000039 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000039 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0017145 ] ) ] . obo:CL_0000015 obo:IAO_0000115 "A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis." ; oboInOwl:hasDbXref "FMA:72290", "MA:0002765", "VHOG:0001531", "ncithesaurus:Spermatogenic_Cell" ; a owl:Class ; rdfs:label "male germ cell" ; rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/574" ; rdfs:subClassOf obo:CL_0000586, [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0007283 ] . obo:CL_0000017 obo:IAO_0000115 "A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids." ; oboInOwl:hasDbXref "BTO:0001275", "CALOHA:TS-0951", "EMAPA:31484", "FBbt:00004936", "FMA:84049", "WBbt:0006799" ; a owl:Class ; rdfs:label "spermatocyte" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000015, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000020 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048137 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000015 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048137 ] ) ] . obo:CL_0000018 obo:IAO_0000115 "A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa." ; oboInOwl:hasDbXref "BTO:0001274", "CALOHA:TS-0950", "EMAPA:31486", "FBbt:00004942", "FMA:72294", "WBbt:0006800" ; oboInOwl:hasExactSynonym "nematoblast" ; a owl:Class ; rdfs:label "spermatid" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000015, obo:CL_0000413, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000657 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001675 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007288 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007289 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000015 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001375 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001675 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007288 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007289 ] ) ] . obo:CL_0000019 obo:IAO_0000115 "A mature male germ cell that develops from a spermatid." ; oboInOwl:hasDbXref "BTO:0001277", "BTO:0002046", "CALOHA:TS-0949", "FBbt:00004954", "FMA:67338", "WBbt:0006798" ; oboInOwl:hasExactSynonym "sperm cell", "spermatozoid", "spermatozoon" ; a owl:Class ; rdfs:label "sperm" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000408, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000018 ] . obo:CL_0000020 obo:IAO_0000115 "An euploid male germ cell of an early stage of spermatogenesis." ; oboInOwl:hasDbXref "BTO:0000958", "CALOHA:TS-2193", "EMAPA:31482", "FBbt:00004934", "FBbt:00004935", "FMA:72291" ; oboInOwl:hasExactSynonym "spermatogonial cell" ; a owl:Class ; rdfs:label "spermatogonium" ; rdfs:subClassOf obo:CL_0000015, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001394 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000015 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001394 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001501 ] ) ] . obo:CL_0000021 obo:IAO_0000115 "Female germ cell is a germ cell that supports female gamete production." ; oboInOwl:hasDbXref "MA:0000388", "VHOG:0001530", "ncithesaurus:Egg" ; a owl:Class ; rdfs:label "female germ cell" ; rdfs:subClassOf obo:CL_0000586, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048477 ] ) ] . obo:CL_0000022 obo:IAO_0000115 "A stem cell that is the precursor of female gametes." ; oboInOwl:hasDbXref "FBbt:00004873" ; a owl:Class ; rdfs:label "female germ line stem cell" ; rdfs:subClassOf obo:CL_0000014, obo:CL_0000021 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000021 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0017145 ] ) ] . obo:CL_0000023 obo:IAO_0000115 "A female germ cell that has entered meiosis." ; oboInOwl:hasDbXref "BTO:0000964", "CALOHA:TS-0711", "FBbt:00004886", "FMA:18644", "MESH:D009865", "WBbt:0006797" ; oboInOwl:hasRelatedSynonym "oogonium" ; a owl:Class ; rdfs:label "oocyte" ; rdfs:subClassOf obo:CL_0000021, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:GO_0007143 ] . obo:CL_0000024 obo:IAO_0000115 "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." ; oboInOwl:hasDbXref "FMA:83673" ; a owl:Class ; rdfs:label "oogonial cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000021, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000670 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000021 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:CL_0000025 obo:IAO_0000115 "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization." ; oboInOwl:hasDbXref "BTO:0000369", "BTO:0003801", "CALOHA:TS-2191", "FBbt:00057012", "FMA:67343", "MA:0000388", "MESH:D010063" ; oboInOwl:hasExactSynonym "mature oocyte", "ovum" ; a owl:Class ; rdfs:label "egg cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000548, obo:CL_0000675, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:GO_0007143 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000023 ] . obo:CL_0000027 obo:IAO_0000115 "A smooth muscle cell derived from the neural crest." ; a owl:Class ; rdfs:label "smooth muscle cell neural crest derived" ; rdfs:subClassOf obo:CL_0000192, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000333 ] ) ] . obo:CL_0000029 oboInOwl:hasExactSynonym "neuron neural crest derived" ; a owl:Class ; rdfs:label "neural crest derived neuron" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002676 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000333 ] ) ] . obo:CL_0000031 obo:IAO_0000115 "A cell that will develop into a neuron often after a migration phase." ; oboInOwl:hasDbXref "BTO:0000930", "FMA:70563" ; oboInOwl:hasExactSynonym "neuroblast" ; a owl:Class ; rdfs:label "neuroblast (sensu Vertebrata)" ; rdfs:subClassOf obo:CL_0000055, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ] . obo:CL_0000034 obo:IAO_0000115 "A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "CALOHA:TS-2086", "FMA:63368" ; oboInOwl:hasExactSynonym "animal stem cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’." ; rdfs:label "stem cell" ; rdfs:subClassOf obo:CL_0000548, obo:CL_0011115, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0017145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0017145 ] ) ] . obo:CL_0000035 obo:IAO_0000115 "A stem cell that self-renews as well as give rise to a single mature cell type." ; oboInOwl:hasDbXref "FMA:70569" ; oboInOwl:hasExactSynonym "unipotent stem cell", "unipotential stem cell" ; a owl:Class ; rdfs:label "single fate stem cell" ; rdfs:subClassOf obo:CL_0000723, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001400 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001400 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0017145 ] ) ] . obo:CL_0000037 obo:IAO_0000115 "A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000725", "CALOHA:TS-0448", "FMA:70337", "FMA:86475", "MESH:D006412", "VHOG:0001485" ; oboInOwl:hasExactSynonym "HSC", "blood forming stem cell", "hemopoietic stem cell" ; oboInOwl:hasRelatedSynonym "colony forming unit hematopoietic" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim, core:human_reference_atlas ; a owl:Class ; rdfs:comment "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative." ; rdfs:label "hematopoietic stem cell" ; rdfs:subClassOf obo:CL_0000723, obo:CL_0008001, obo:CL_0011026, [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002981 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000566 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0002244 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000988 [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002981 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0002244 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048103 ] ) ] . obo:CL_0000038 obo:IAO_0000115 "A progenitor cell committed to the erythroid lineage." ; oboInOwl:hasDbXref "BTO:0004911" ; oboInOwl:hasRelatedSynonym "BFU-E", "CFU-E", "blast forming unit erythroid", "burst forming unit erythroid", "colony forming unit erythroid", "erythroid stem cell" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:label "erythroid progenitor cell" ; rdfs:subClassOf obo:CL_0000764, obo:CL_0000839, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000050 ] . obo:CL_0000039 obo:IAO_0000115 "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." ; oboInOwl:inSubset ubprop:_upper_level ; a owl:Class ; rdfs:comment "Originally this term had some plant germ line cell children." ; rdfs:label "germ line cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0022414 ] ; owl:disjointWith obo:CL_0002371 . obo:CL_0000048 obo:IAO_0000115 "A stem cell that can give rise to multiple lineages of cells." ; oboInOwl:hasDbXref "FMA:84789" ; oboInOwl:hasExactSynonym "multi-fate stem cell", "multifate stem cell", "multipotent cell", "multipotent stem cell" ; a owl:Class ; rdfs:label "multi fate stem cell" ; rdfs:subClassOf obo:CL_0000034, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002371 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001402 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0017145 ] ) ] . obo:CL_0000049 obo:IAO_0000115 "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0004730" ; oboInOwl:hasExactSynonym "CMP", "common myeloid precursor" ; oboInOwl:hasRelatedSynonym "CFU-GEMM", "CFU-S", "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte", "multipotential myeloid stem cell", "myeloid stem cell", "pluripotent stem cell (bone marrow)" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "This cell type is intended to be compatible with any vertebrate common myeloid progenitor. For mammalian CMP known to be CD34-positive, please use the term 'common myeloid progenitor, CD34-positive' (CL_0001059)." ; rdfs:label "common myeloid progenitor" ; rdfs:subClassOf obo:CL_0002032 ; owl:disjointWith obo:CL_0000050, obo:CL_0000051 . obo:CL_0000050 obo:IAO_0000115 "A progenitor cell committed to the megakaryocyte and erythroid lineages." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasExactSynonym "CFU-EM", "CFU-MegE", "MEP", "Meg/E progenitor", "colony forming unit erythroid megakaryocyte", "megakaryocyte/erythrocyte progenitor", "megakaryocyte/erythroid progenitor cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2." ; rdfs:label "megakaryocyte-erythroid progenitor cell" ; rdfs:subClassOf obo:CL_0000763, obo:CL_0002032, obo:CL_0011026, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030218 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030219 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002032 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030218 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030219 ] ) ] . obo:CL_0000051 obo:IAO_0000115 "A oligopotent progenitor cell committed to the lymphoid lineage." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasExactSynonym "CLP", "common lymphocyte precursor", "common lymphocyte progenitor", "common lymphoid precursor" ; oboInOwl:hasRelatedSynonym "ELP", "committed lymphopoietic stem cell", "early lymphocyte progenitor", "lymphoid stem cell", "lymphopoietic stem cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative." ; rdfs:label "common lymphoid progenitor" ; rdfs:subClassOf obo:CL_0002032, obo:CL_0011026, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030098 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002032 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030098 ] ) ] . obo:CL_0000052 obo:IAO_0000115 "A stem cell from which all cells of the body can form." ; oboInOwl:hasDbXref "FMA:84790", "MESH:D039901" ; oboInOwl:hasExactSynonym "totipotential stem cell" ; a owl:Class ; rdfs:label "totipotent stem cell" ; rdfs:subClassOf obo:CL_0000723 . obo:CL_0000055 obo:IAO_0000115 "A precursor cell with a limited number of potential fates." ; oboInOwl:hasDbXref "BTO:0000125", "FMA:84782" ; oboInOwl:hasExactSynonym "blast cell" ; a owl:Class ; rdfs:comment "define using PATO mulit-potent or oligopotent?" ; rdfs:label "non-terminally differentiated cell" ; rdfs:subClassOf obo:CL_0011115 . obo:CL_0000056 obo:IAO_0000115 "A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair." ; oboInOwl:hasDbXref "BTO:0000222", "CALOHA:TS-0650", "FBbt:00005083", "FMA:70335", "VHOG:0001529" ; a owl:Class ; rdfs:label "myoblast" ; rdfs:subClassOf obo:CL_0000680 . obo:CL_0000057 obo:IAO_0000115 "A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000452", "CALOHA:TS-0362", "FMA:63877", "VHOG:0001482" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "These cells may be vimentin-positive, fibronectin-positive, fsp1-positive, MMP-1-positive, collagen I-positive, collagen III-positive, and alpha-SMA-negative." ; rdfs:label "fibroblast" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0002320, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000134 ] . obo:CL_0000058 obo:IAO_0000115 "Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell." ; oboInOwl:hasDbXref "BTO:0003607", "FMA:66783" ; oboInOwl:hasExactSynonym "chrondoplast" ; a owl:Class ; rdfs:label "chondroblast" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000055, obo:CL_0002320, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0007009 ], [ a owl:Restriction ; owl:onProperty obo:RO_0003000 ; owl:someValuesFrom obo:UBERON_0002418 ] . obo:CL_0000064 obo:IAO_0000115 "A cell that has a filiform extrusion of the cell surface." ; oboInOwl:hasDbXref "VHOG:0001532", "XAO:0000031" ; a owl:Class ; rdfs:label "ciliated cell" ; rdfs:subClassOf obo:CL_0000003, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005929 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:CL_0000066 obo:IAO_0000115 "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000414", "CALOHA:TS-2026", "CARO:0000077", "FBbt:00000124", "FMA:66768", "WBbt:0003672" ; oboInOwl:hasExactSynonym "epitheliocyte" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "epithelial cell" ; rdfs:subClassOf obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000483 ] ; owl:disjointWith obo:CL_0000738 . obo:CL_0000067 obo:IAO_0000115 "An epithelial cell that has a cilia." ; oboInOwl:hasDbXref "FMA:70605" ; a owl:Class ; rdfs:label "ciliated epithelial cell" ; rdfs:subClassOf obo:CL_0000064, obo:CL_0000066 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:CL_0000068 obo:IAO_0000115 "An epithelial cell that is part of a duct." ; a owl:Class ; rdfs:label "duct epithelial cell" ; rdfs:subClassOf obo:CL_0000066, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000058 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000058 ] ) ] . obo:CL_0000069 a owl:Class ; rdfs:label "branched duct epithelial cell" ; rdfs:subClassOf obo:CL_0000068 . obo:CL_0000071 obo:IAO_0000115 "An endothelial cell that lines the vasculature." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasExactSynonym "cuboidal endothelial cell of vascular tree" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "blood vessel endothelial cell" ; rdfs:subClassOf obo:CL_0000076, obo:CL_0002139, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004638 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002546 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000076 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004638 ] ) ] . obo:CL_0000072 a owl:Class ; rdfs:label "non-branched duct epithelial cell" ; rdfs:subClassOf obo:CL_0000068, obo:CL_0002078 . obo:CL_0000075 obo:IAO_0000115 "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "columnar/cuboidal epithelial cell" ; rdfs:subClassOf obo:CL_0000066, obo:CL_0002371 . obo:CL_0000076 oboInOwl:hasDbXref "CALOHA:TS-1249" ; a owl:Class ; rdfs:label "squamous epithelial cell" ; rdfs:subClassOf obo:CL_0000066 . obo:CL_0000077 obo:IAO_0000115 "A flattened epithelial cell of mesenchymal origin that lines the serous cavity." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:66773" ; oboInOwl:hasExactSynonym "mesotheliocyte" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "mesothelial cell" ; rdfs:subClassOf obo:CL_0000076, obo:CL_0000213, obo:CL_0002078 . obo:CL_0000080 obo:IAO_0000115 "A cell which moves among different tissues of the body, via blood, lymph, or other medium." ; a owl:Class ; rdfs:label "circulating cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000179 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000179 ] ) ] . obo:CL_0000081 obo:IAO_0000115 "A cell found predominately in the blood." ; oboInOwl:hasDbXref "FMA:62844", "MESH:D001773" ; a owl:Class ; rdfs:label "blood cell" ; rdfs:subClassOf obo:CL_0000988, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0008015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000988 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0008015 ] ) ] . obo:CL_0000082 obo:IAO_0000115 "An epithelial cell of the lung." ; oboInOwl:hasDbXref "BTO:0004299" ; oboInOwl:hasExactSynonym "lung epithelial cell" ; a owl:Class ; rdfs:label "epithelial cell of lung" ; rdfs:subClassOf obo:CL_0000066, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_0000083 obo:IAO_0000115 "An epithelial cell of the pancreas." ; oboInOwl:hasDbXref "BTO:0000028" ; oboInOwl:hasExactSynonym "pancreas epithelial cell", "pancreatic epithelial cell" ; a owl:Class ; rdfs:label "epithelial cell of pancreas" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000066, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001264 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000223 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001264 ] ) ] . obo:CL_0000084 obo:IAO_0000115 "A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000782", "CALOHA:TS-1001", "FMA:62870", "MESH:D013601", "VHOG:0001479" ; oboInOwl:hasExactSynonym "T lymphocyte", "T-cell", "T-lymphocyte" ; oboInOwl:hasRelatedSynonym "immature T cell", "mature T cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "T cell" ; rdfs:subClassOf obo:CL_0000542, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000827 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0002456 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000542 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0002456 ] ) ] . obo:CL_0000086 obo:IAO_0000233 "https://github.com/obophenotype/cell-ontology/issues/1935" ; obo:IAO_0100001 obo:CL_0000014 ; oboInOwl:hasDbXref "FBbt:00004861" ; a owl:Class ; rdfs:comment "Obsoleted as there is no need for a term specific for nematods and protostomes." ; rdfs:label "obsolete germ line stem cell (sensu Nematoda and Protostomia)" ; owl:deprecated true . obo:CL_0000095 a owl:Class ; rdfs:label "neuron associated cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0002319, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000133 ] . obo:CL_0000098 obo:IAO_0000115 "A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells." ; oboInOwl:hasBroadSynonym "neuroepithelial cell" ; oboInOwl:hasDbXref "BTO:0004301" ; a owl:Class ; rdfs:comment "The term \"neuroepithelial cell\" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710)." ; rdfs:label "sensory epithelial cell" ; rdfs:subClassOf obo:CL_0000066, obo:CL_0000197, obo:CL_0002371 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0050906 ] ) ] . obo:CL_0000099 obo:IAO_0000115 "Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0003811", "FBbt:00005125", "FMA:67313", "WBbt:0005113" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "interneuron" ; rdfs:subClassOf obo:CL_0000540 . obo:CL_0000100 obo:IAO_0000115 "An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement." ; oboInOwl:hasDbXref "BTO:0000312", "FBbt:00005123", "FMA:83617", "WBbt:0005409" ; oboInOwl:hasExactSynonym "motoneuron" ; a owl:Class ; rdfs:label "motor neuron" ; rdfs:subClassOf obo:CL_0000527 . obo:CL_0000101 obo:IAO_0000115 "Any neuron having a sensory function; an afferent neuron conveying sensory impulses." ; oboInOwl:hasDbXref "BTO:0001037", "FBbt:00005124", "FMA:84649", "MESH:D011984", "WBbt:0005759" ; a owl:Class ; rdfs:label "sensory neuron" ; rdfs:subClassOf obo:CL_0000526, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0050906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0050906 ] ) ] . obo:CL_0000107 obo:IAO_0000115 "A neuron whose cell body is within an autonomic ganglion." ; oboInOwl:hasDbXref "FMA:80121" ; a owl:Class ; rdfs:label "autonomic neuron" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_2000032, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002410 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002410 ] ) ] . obo:CL_0000108 obo:IAO_0000115 "A neuron that uses acetylcholine as a vesicular neurotransmitter." ; oboInOwl:hasDbXref "BTO:0004902", "FBbt:00007173", "FMA:84796", "MESH:D059329", "WBbt:0006840" ; a owl:Class ; rdfs:label "cholinergic neuron" ; rdfs:subClassOf obo:CL_0000151, obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0014055 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0014055 ] ) ] . obo:CL_0000115 obo:IAO_0000115 "An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0001176", "CALOHA:TS-0278", "FMA:66772" ; oboInOwl:hasExactSynonym "endotheliocyte" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "From FMA: 9.07.2001: Endothelial cell has always been classified as a kind of epithelial cell, specifically a squamous cell but that is not true. First, endothelial cell can either be squamous or cuboidal (e.g. high-endothelial cell) and secondly, it has different embryological derivation (mesodermal) than a true epithelial cell (ectodermal and endodermal). The basis for present classification is the fact that it comprises the outermost layer or lining of anatomical structures (location-based) but a better structural basis for the differentia is the cytoskeleton of the cell. Endothelial cell has vimentin filaments while an epithelial cell has keratin filaments. [Onard]." ; rdfs:label "endothelial cell" ; rdfs:subClassOf obo:CL_0000213, obo:CL_0002078 . obo:CL_0000117 a owl:Class ; rdfs:label "CNS neuron (sensu Vertebrata)" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001017 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000031 ] . obo:CL_0000125 obo:IAO_0000115 "A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons." ; oboInOwl:hasDbXref "BTO:0002606", "CALOHA:TS-0415", "FBbt:00005144", "FMA:54536" ; oboInOwl:hasExactSynonym "neuroglial cell" ; oboInOwl:hasRelatedSynonym "neuroglia" ; a owl:Class ; rdfs:comment "Not all glial cells develop from glioblasts, with microglia developing from the mesoderm instead. See https://github.com/obophenotype/cell-ontology/issues/1571" ; rdfs:label "glial cell" ; rdfs:subClassOf obo:CL_0000095 . obo:CL_0000133 obo:IAO_0000115 "Ectoderm destined to be nervous tissue." ; oboInOwl:hasExactSynonym "neurectoderm cell" ; a owl:Class ; rdfs:label "neurectodermal cell" ; rdfs:subClassOf obo:CL_0000221 . obo:CL_0000134 obo:IAO_0000115 "A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs." ; oboInOwl:hasDbXref "BTO:0002625", "BTO:0003298", "FMA:70546" ; oboInOwl:hasNarrowSynonym "BMSC", "bone marrow stromal cells", "colony-forming unit-fibroblast", "marrow stromal cells" ; oboInOwl:hasRelatedSynonym "CFU-F", "MSC", "mesenchymal precursor cell", "mesenchymal progenitor cells", "mesenchymal stem cell", "mesenchymal stromal cell", "mesenchymal stromal cells", "stem cells, mesenchymal" ; a owl:Class ; rdfs:comment "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2." ; rdfs:label "mesenchymal stem cell" ; rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/474" ; rdfs:subClassOf obo:CL_0000048, obo:CL_0002320 . obo:CL_0000136 obo:IAO_0000115 "A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000443", "CALOHA:TS-0012", "FMA:63880" ; oboInOwl:hasExactSynonym "adipocyte", "adipose cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "fat cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000325, obo:CL_0002320, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000134 ] . obo:CL_0000138 obo:IAO_0000115 "Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell." ; oboInOwl:hasDbXref "BTO:0000249", "CALOHA:TS-0138", "FMA:66782" ; oboInOwl:hasExactSynonym "cartilage cell" ; a owl:Class ; rdfs:label "chondrocyte" ; rdfs:subClassOf obo:CL_0000153, obo:CL_0000667, [ a owl:Restriction ; owl:onProperty obo:RO_0001025 ; owl:someValuesFrom obo:UBERON_0002418 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000058 ] . obo:CL_0000145 obo:IAO_0000115 "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response." ; oboInOwl:hasBroadSynonym "APC" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:comment "Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells." ; rdfs:label "professional antigen presenting cell" ; rdfs:subClassOf obo:CL_0000738, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0002504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000738 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0002504 ] ) ] . obo:CL_0000147 obo:IAO_0000115 "A pigment cell is a cell that contains pigment granules." ; oboInOwl:hasDbXref "VHOG:0001678" ; oboInOwl:hasExactSynonym "chromatocyte", "chromatophore" ; a owl:Class ; rdfs:label "pigment cell" ; rdfs:subClassOf obo:CL_0000325 . obo:CL_0000149 oboInOwl:hasBroadSynonym "pigment cell" ; a owl:Class ; rdfs:label "visual pigment cell" ; rdfs:subClassOf obo:CL_0000147, obo:CL_0000548 . obo:CL_0000150 obo:IAO_0000115 "A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules." ; oboInOwl:hasDbXref "CALOHA:TS-2085", "FMA:86494" ; a owl:Class ; rdfs:label "glandular epithelial cell" ; rdfs:subClassOf obo:CL_0000066, obo:CL_0000151, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0006799 ] . obo:CL_0000151 obo:IAO_0000115 "A cell that specializes in controlled release of one or more substances." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0003659", "FMA:86916" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "secretory cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0032940 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0032940 ] ) ] . obo:CL_0000152 obo:IAO_0000115 "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct." ; oboInOwl:hasDbXref "FMA:16014" ; a owl:Class ; rdfs:label "exocrine cell" ; rdfs:subClassOf obo:CL_0000151, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002365 ] ) ] . obo:CL_0000153 obo:IAO_0000115 "A cell that secretes glycosaminoglycans." ; oboInOwl:hasExactSynonym "GAG secreting cell" ; oboInOwl:hasNarrowSynonym "hyaluronic acid secreting cell" ; a owl:Class ; rdfs:label "glycosaminoglycan secreting cell" ; rdfs:subClassOf obo:CL_0000327, obo:CL_0000447 . obo:CL_0000154 a owl:Class ; rdfs:label "protein secreting cell" ; rdfs:subClassOf obo:CL_0000151, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009306 ] ) ] . obo:CL_0000157 obo:IAO_0000115 "A cell that specializes in secretion of surfactant in the alveoli of the lung." ; a owl:Class ; rdfs:label "surfactant secreting cell" ; rdfs:subClassOf obo:CL_0000151, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0043129 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0043129 ] ) ] . obo:CL_0000158 obo:IAO_0000115 "Epithelial progenitor cell of the lung. Club cells are dome-shaped with short microvilli but no cilia. They function to protect the bronchiolar epithelium. Club cells also multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0004811", "FMA:14119" ; oboInOwl:hasExactSynonym "Clara cell", "bronchiolar non-ciliated cell", "club cell of bronchiole" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "club cell" ; rdfs:subClassOf obo:CARO_0000006, obo:CL_0000157, obo:CL_0002328, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001789 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:GO_0005902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002328 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001789 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:GO_0005902 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0032940 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0043129 ] ) ] . obo:CL_0000159 a owl:Class ; rdfs:label "seromucus secreting cell" ; rdfs:subClassOf obo:CL_0000151 . obo:CL_0000161 a owl:Class ; rdfs:label "acid secreting cell" ; rdfs:subClassOf obo:CL_0000151, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0046717 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0046717 ] ) ] . obo:CL_0000163 obo:IAO_0000115 "A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:83809" ; oboInOwl:hasExactSynonym "endocrinocyte" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "endocrine cell" ; rdfs:subClassOf obo:CL_0000151, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000949 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0046879 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:UBERON_0001009 ] ) ] ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0046879 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:UBERON_0001009 ] ) ] ] ) ] . obo:CL_0000164 obo:IAO_0000115 "An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas." ; oboInOwl:hasDbXref "BTO:0003865", "FMA:62930", "MESH:D019858" ; a owl:Class ; rdfs:label "enteroendocrine cell" ; rdfs:subClassOf obo:CL_0000150, obo:CL_0000163 . obo:CL_0000165 obo:IAO_0000115 "A neuron that is capable of some hormone secretion in response to neuronal signals." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0002691", "FBbt:00005130", "FMA:83810" ; oboInOwl:hasRelatedSynonym "neurosecretory cell", "neurosecretory neuron" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment """The neurosecretory cell is neither an ordinary neuron nor an endocrine cell, but a combination of both. Its neuronal features resemble those of ordinary neurons concerning both structure and function. The production of a visible secretory material marks the neurosecretory neuron as a gland cell, and the fact that extractable cellular products act in the manner of hormones places it in the realm of endocrine elements. The modern definition of neurosecretion has evolved to include the release of any neuronal secretory product from a neuron.""" ; rdfs:label "neuroendocrine cell" ; rdfs:subClassOf obo:CL_0000163, obo:CL_0000527, obo:CL_0000710 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0046879 ] ) ] . obo:CL_0000167 a owl:Class ; rdfs:label "peptide hormone secreting cell" ; rdfs:subClassOf obo:CL_0000151, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030072 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030072 ] ) ] . obo:CL_0000168 oboInOwl:hasDbXref "BTO:0000783" ; a owl:Class ; rdfs:label "insulin secreting cell" ; rdfs:subClassOf obo:CL_0000154, obo:CL_0000167, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030073 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030073 ] ) ] . obo:CL_0000169 obo:IAO_0000115 "A cell that secretes insulin and is located towards the center of the islets of Langerhans." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasBroadSynonym "beta cell" ; oboInOwl:hasDbXref "BTO:0000783", "EV:0200009", "FMA:70586", "MA:0002419", "ncithesaurus:Beta_Cell" ; oboInOwl:hasExactSynonym "B-cell of pancreatic islet", "beta cell of pancreatic islet", "insulin-secreting cell", "pancreatic B cell", "pancreatic B-cell", "pancreatic beta cell", "pancreatic islet core", "type B enteroendocrine cell" ; oboInOwl:hasRelatedSynonym "beta cell islet" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression." ; rdfs:label "type B pancreatic cell" ; rdfs:subClassOf obo:CL_0000168, obo:CL_0008024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000006 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000164 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000006 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030073 ] ) ] . obo:CL_0000170 obo:IAO_0000115 "A cell that secretes glucagon." ; oboInOwl:hasDbXref "FMA:84045" ; oboInOwl:hasExactSynonym "glucagon-secreting cell" ; a owl:Class ; rdfs:label "glucagon secreting cell" ; rdfs:subClassOf obo:CL_0000167, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0070091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0070091 ] ) ] . obo:CL_0000171 obo:IAO_0000115 "A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000990", "FMA:70585", "MESH:D050416" ; oboInOwl:hasExactSynonym "alpha cell of islet of Langerhans", "pancreatic alpha cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "pancreatic A cell" ; rdfs:subClassOf obo:CL_0002067, obo:CL_0008024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000006 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002067 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001264 ] ) ] . obo:CL_0000172 a owl:Class ; rdfs:label "somatostatin secreting cell" ; rdfs:subClassOf obo:CL_0000167, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0070253 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0070253 ] ) ] . obo:CL_0000173 obo:IAO_0000115 "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000803", "FMA:70587" ; oboInOwl:hasExactSynonym "D-cell of pancreatic islet", "delta cell of islet", "delta cell of pancreatic islet", "pancreatic D-cell", "pancreatic delta cell", "somatostatin-secreting pancreatic cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "pancreatic D cell" ; rdfs:subClassOf obo:CL_0000502, obo:CL_0008024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000006 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001264 ] ) ] . obo:CL_0000174 a owl:Class ; rdfs:label "steroid hormone secreting cell" ; rdfs:subClassOf obo:CL_0000151, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0035929 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0035929 ] ) ] . obo:CL_0000182 obo:IAO_0000115 "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000575", "CALOHA:TS-0454", "FMA:14515" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "Hepatocytes are reportedly MHC Class I-positive and MHC Class II-positive." ; rdfs:label "hepatocyte" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000066, obo:CL_0000417, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002107 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0005026 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0006699 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0098754 ] . obo:CL_0000183 obo:IAO_0000115 "A cell whose primary function is to shorten." ; a owl:Class ; rdfs:label "contractile cell" ; rdfs:subClassOf obo:CL_0000003 . obo:CL_0000187 obo:IAO_0000115 "A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." ; oboInOwl:hasDbXref "BTO:0000888", "BTO:0000902", "CALOHA:TS-2032", "FBbt:00005074", "FMA:67328", "WBbt:0003675" ; oboInOwl:hasExactSynonym "muscle fiber", "myocyte" ; a owl:Class ; rdfs:label "muscle cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000183, obo:CL_0000393, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000056 ] . obo:CL_0000188 obo:IAO_0000115 "A somatic cell located in skeletal muscle." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0004392", "CALOHA:TS-2158", "FMA:9727" ; oboInOwl:hasExactSynonym "skeletal muscle cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "cell of skeletal muscle" ; rdfs:subClassOf obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001134 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002371 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001134 ] ) ] . obo:CL_0000192 obo:IAO_0000115 "A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast)." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasBroadSynonym "non-striated muscle cell" ; oboInOwl:hasDbXref "BTO:0004576", "CALOHA:TS-2159", "FMA:14072" ; oboInOwl:hasExactSynonym "SMCs", "myocytes, smooth muscle", "smooth muscle fiber" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "smooth muscle cell" ; rdfs:subClassOf obo:CL_0008000, obo:CL_0008007, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000514 ] . obo:CL_0000197 obo:IAO_0000115 "A cell that is capable of detection of a stimulus involved in sensory perception." ; oboInOwl:hasDbXref "MESH:D011984" ; oboInOwl:hasExactSynonym "receptor cell" ; a owl:Class ; rdfs:label "sensory receptor cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001032 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0050906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001032 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0050906 ] ) ] . obo:CL_0000210 obo:IAO_0000115 "A cell specialized to detect and transduce light." ; oboInOwl:hasDbXref "BTO:0001060", "CALOHA:TS-0868", "FMA:86740" ; a owl:Class ; rdfs:label "photoreceptor cell" ; rdfs:subClassOf obo:CL_0000006, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0050962 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0050962 ] ) ] . obo:CL_0000211 obo:IAO_0000115 "A cell whose function is determined by the generation or the reception of an electric signal." ; a owl:Class ; rdfs:label "electrically active cell" ; rdfs:subClassOf obo:CL_0000003 . obo:CL_0000213 obo:IAO_0000115 "A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism." ; oboInOwl:hasExactSynonym "boundary cell" ; a owl:Class ; rdfs:label "lining cell" ; rdfs:subClassOf obo:CL_0000215 . obo:CL_0000214 obo:IAO_0000115 "A cell located in the synovial joint." ; oboInOwl:hasDbXref "CALOHA:TS-0995" ; oboInOwl:hasExactSynonym "synoviocyte" ; a owl:Class ; rdfs:label "synovial cell" ; rdfs:subClassOf obo:CL_0000213, obo:CL_0002078, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002217 ] . obo:CL_0000215 obo:IAO_0000115 "A cell whose primary function is to prevent the transport of stuff across compartments." ; a owl:Class ; rdfs:label "barrier cell" ; rdfs:subClassOf obo:CL_0000003 . obo:CL_0000216 obo:IAO_0000115 "A supporting cell projecting inward from the basement membrane of seminiferous tubules. They surround and nourish the developing male germ cells and secrete androgen binding protein. Their tight junctions with the spermatogonia and spermatocytes provide a blood-testis barrier." ; oboInOwl:hasDbXref "BTO:0001238", "CALOHA:TS-0922", "FMA:72298", "VHOG:0001348" ; a owl:Class ; rdfs:label "Sertoli cell" ; rdfs:subClassOf obo:CL_0000511, obo:CL_0000630, obo:CL_0002625 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000630 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001343 ] ) ] . obo:CL_0000219 obo:IAO_0000115 "A cell that moves by its own activities." ; a owl:Class ; rdfs:label "motile cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048870 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048870 ] ) ] . obo:CL_0000221 obo:IAO_0000115 "A cell of the outer of the three germ layers of the embryo." ; oboInOwl:hasDbXref "FMA:72549" ; oboInOwl:hasExactSynonym "ectoderm cell" ; a owl:Class ; rdfs:label "ectodermal cell" ; rdfs:subClassOf obo:CL_0002321, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000924 ] . obo:CL_0000222 obo:IAO_0000115 "A cell of the middle germ layer of the embryo." ; oboInOwl:hasDbXref "FMA:72554" ; oboInOwl:hasExactSynonym "mesoblast", "mesoderm cell" ; a owl:Class ; rdfs:label "mesodermal cell" ; rdfs:subClassOf obo:CL_0002321, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000926 ] . obo:CL_0000223 obo:IAO_0000115 "A cell of the inner of the three germ layers of the embryo." ; oboInOwl:hasDbXref "FMA:72555" ; oboInOwl:hasExactSynonym "endoderm cell" ; a owl:Class ; rdfs:label "endodermal cell" ; rdfs:subClassOf obo:CL_0002321, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000925 ] . obo:CL_0000225 obo:IAO_0000115 "A cell that lacks a nucleus." ; oboInOwl:hasDbXref "FMA:68647" ; oboInOwl:hasExactSynonym "non-nucleated cell" ; a owl:Class ; rdfs:label "anucleate cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001405 ] ; owl:disjointWith obo:CL_0002242 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001405 ] ) ] . obo:CL_0000226 obo:IAO_0000115 "A cell with a single nucleus." ; a owl:Class ; rdfs:label "single nucleate cell" ; rdfs:subClassOf obo:CL_0002242, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001407 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001407 ] ) ] . obo:CL_0000227 a owl:Class ; rdfs:label "binucleate cell" ; rdfs:subClassOf obo:CL_0000228, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001406 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001406 ] ) ] . obo:CL_0000228 obo:IAO_0000115 "A cell with more than one nucleus." ; oboInOwl:hasDbXref "AEO:0000203", "WBbt:0008074" ; oboInOwl:hasExactSynonym "syncitium", "syncytial cell", "syncytium" ; a owl:Class ; rdfs:label "multinucleate cell" ; rdfs:subClassOf obo:CL_0002242, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001908 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001908 ] ) ] . obo:CL_0000232 obo:IAO_0000115 "A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000424", "CALOHA:TS-0290", "FMA:81100" ; oboInOwl:hasExactSynonym "RBC", "red blood cell" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim, core:human_reference_atlas ; a owl:Class ; rdfs:label "erythrocyte" ; rdfs:subClassOf obo:CL_0000081, obo:CL_0000329, obo:CL_0000764, [ a owl:Restriction ; owl:onProperty obo:CL_4030045 ; owl:someValuesFrom obo:GO_0005840 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001945 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002039 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000558 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000764 [ a owl:Restriction ; owl:onProperty obo:CL_4030045 ; owl:someValuesFrom obo:GO_0005840 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001945 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002039 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0008015 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0015671 ] ) ] . obo:CL_0000255 oboInOwl:hasDbXref "MESH:D005057" ; a owl:Class ; rdfs:label "eukaryotic cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ] ) ] . obo:CL_0000257 a owl:Class ; rdfs:label "Eumycetozoan cell" ; rdfs:subClassOf obo:CL_0000255, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_142796 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_142796 ] ) ] . obo:CL_0000287 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "eye photoreceptor cell" ; rdfs:subClassOf obo:CL_0000210, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000970 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000210 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000970 ] ) ] . obo:CL_0000293 obo:IAO_0000115 "A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism." ; a owl:Class ; rdfs:label "structural cell" ; rdfs:subClassOf obo:CL_0000003 . obo:CL_0000300 obo:IAO_0000115 "A mature sexual reproductive cell having a single set of unpaired chromosomes." ; oboInOwl:hasDbXref "CALOHA:TS-0395", "FBbt:00005412", "FMA:18649" ; oboInOwl:hasExactSynonym "haploid nucleated cell" ; oboInOwl:hasRelatedSynonym "haploid germ cell" ; a owl:Class ; rdfs:label "gamete" ; rdfs:subClassOf obo:CL_0000413, obo:CL_0000586, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001375 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009566 ] ) ] . obo:CL_0000306 oboInOwl:hasExactSynonym "lens cell" ; a owl:Class ; rdfs:label "crystallin accumulating cell" ; rdfs:subClassOf obo:CL_0000325 . obo:CL_0000307 obo:IAO_0000115 "An epithelial cell found in the trachea." ; oboInOwl:hasDbXref "FBbt:00005038", "FMA:74793" ; oboInOwl:hasExactSynonym "tracheocyte" ; a owl:Class ; rdfs:comment "This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell'" ; rdfs:label "tracheal epithelial cell" ; rdfs:subClassOf obo:CL_0002202, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003126 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000377 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003126 ] ) ] . obo:CL_0000313 obo:IAO_0000115 "Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0003687", "FMA:62511" ; oboInOwl:hasExactSynonym "serous cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "serous secreting cell" ; rdfs:subClassOf obo:CL_0000159 . obo:CL_0000319 oboInOwl:hasDbXref "BTO:0003689" ; oboInOwl:hasExactSynonym "mucous cell" ; a owl:Class ; rdfs:label "mucus secreting cell" ; rdfs:subClassOf obo:CL_0000159, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0070254 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0070254 ] ) ] . obo:CL_0000325 obo:IAO_0000115 "A cell that is specialised to accumulate a particular substance(s)." ; oboInOwl:inSubset ubprop:_upper_level ; a owl:Class ; rdfs:label "stuff accumulating cell" ; rdfs:subClassOf obo:CL_0000003 . obo:CL_0000327 a owl:Class ; rdfs:label "extracellular matrix secreting cell" ; rdfs:subClassOf obo:CL_0000499 . obo:CL_0000329 a owl:Class ; rdfs:label "oxygen accumulating cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0015671 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0015671 ] ) ] . obo:CL_0000333 obo:IAO_0000115 "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body." ; oboInOwl:hasDbXref "FMA:86667" ; a owl:Class ; rdfs:label "migratory neural crest cell" ; rdfs:subClassOf obo:CL_0000219, obo:CL_0011012, obo:CL_0011026, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0007004 ] . obo:CL_0000335 obo:IAO_0000115 "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors." ; a owl:Class ; rdfs:label "mesenchyme condensation cell" ; rdfs:subClassOf obo:CL_0008019 . obo:CL_0000347 obo:IAO_0000115 "A cell of the sclera of the eye." ; a owl:Class ; rdfs:label "scleral cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000293, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001773 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000293 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001773 ] ) ] . obo:CL_0000348 obo:IAO_0000115 "A cell of the choroid of the eye." ; a owl:Class ; rdfs:label "choroidal cell of the eye" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000293, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001776 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000293 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001776 ] ) ] . obo:CL_0000349 a owl:Class ; rdfs:label "extraembryonic cell" ; rdfs:subClassOf obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000478 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000548 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000478 ] ) ] . obo:CL_0000351 obo:IAO_0000115 "A cell lining the outside of the blastocyst. After binding to the endometrium, trophoblast cells develop into two distinct layers, an inner layer of mononuclear cytotrophoblast cells and an outer layer of continuous multinuclear cytoplasm, the syncytiotrophoblast cells, which form the early fetal-maternal interface." ; oboInOwl:hasDbXref "FMA:83028" ; oboInOwl:hasExactSynonym "trophoblastic cell" ; a owl:Class ; rdfs:label "trophoblast cell" ; rdfs:subClassOf obo:CL_0000349, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000358 ] . obo:CL_0000352 obo:IAO_0000115 "A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation." ; a owl:Class ; rdfs:label "epiblast cell" ; rdfs:subClassOf obo:CL_0000052 . obo:CL_0000353 obo:IAO_0000115 "An undifferentiated cell produced by early cleavages of the fertilized egg (zygote)." ; oboInOwl:hasDbXref "BTO:0001473", "FMA:72551" ; oboInOwl:hasExactSynonym "blastomere" ; a owl:Class ; rdfs:label "blastoderm cell" ; rdfs:subClassOf obo:CL_0000007 . obo:CL_0000354 oboInOwl:hasDbXref "ncithesaurus:Blastemal_Cell" ; oboInOwl:hasExactSynonym "blastema cell" ; a owl:Class ; rdfs:label "blastemal cell" ; rdfs:subClassOf obo:CL_0000048 . obo:CL_0000355 obo:IAO_0000115 "A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell." ; oboInOwl:hasDbXref "FMA:86767" ; a owl:Class ; rdfs:comment "Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo." ; rdfs:label "multi-potent skeletal muscle stem cell" ; rdfs:subClassOf obo:CL_0000048, obo:CL_0000188 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000048 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001134 ] ) ] . obo:CL_0000358 obo:IAO_0000115 "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning." ; a owl:Class ; rdfs:label "sphincter associated smooth muscle cell" ; rdfs:subClassOf obo:CL_0000192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004590 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004590 ] ) ] . obo:CL_0000359 obo:IAO_0000115 "A smooth muscle cell associated with the vasculature." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasExactSynonym "VSMC", "vascular smooth muscle cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "vascular associated smooth muscle cell" ; rdfs:subClassOf obo:CL_0000192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002049 ] ) ] . obo:CL_0000362 obo:IAO_0000115 "An epithelial cell of the integument (the outer layer of an organism)." ; oboInOwl:hasDbXref "BTO:0001470", "CALOHA:TS-0283", "FMA:62411", "MESH:D000078404" ; oboInOwl:hasExactSynonym "cell of epidermis" ; oboInOwl:hasNarrowSynonym "epithelial cell of skin" ; a owl:Class ; rdfs:label "epidermal cell" ; rdfs:subClassOf obo:CL_0002159, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007376 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007376 ] ) ] . obo:CL_0000365 obo:IAO_0000115 "Diploid cell produced by the fusion of sperm cell nucleus and egg cell." ; oboInOwl:hasBroadSynonym "zygote" ; oboInOwl:hasDbXref "BTO:0000854", "EHDAA2:0004546", "FMA:72395" ; a owl:Class ; rdfs:label "animal zygote" ; rdfs:subClassOf obo:CL_0000007, obo:CL_0010017 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0010017 [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ] ) ] . obo:CL_0000377 a owl:Class ; rdfs:label "tracheoblast" ; rdfs:subClassOf obo:CL_0000069 . obo:CL_0000393 obo:IAO_0000115 "A cell whose function is determined by its response to an electric signal." ; a owl:Class ; rdfs:label "electrically responsive cell" ; rdfs:subClassOf obo:CL_0000211 . obo:CL_0000397 a owl:Class ; rdfs:label "ganglion interneuron" ; rdfs:subClassOf obo:CL_0000099, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0000045 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000099 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0000045 ] ) ] . obo:CL_0000402 a owl:Class ; rdfs:label "CNS interneuron" ; rdfs:subClassOf obo:CL_0000099, obo:CL_0000117, obo:CL_2000029 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000099 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0001017 ] ) ] . obo:CL_0000404 obo:IAO_0000115 "A cell that initiates an electrical signal and passes that signal to another cell." ; a owl:Class ; rdfs:label "electrically signaling cell" ; rdfs:subClassOf obo:CL_0000211 . obo:CL_0000408 oboInOwl:hasDbXref "BTO:0001277", "CALOHA:TS-0949" ; a owl:Class ; rdfs:label "male gamete" ; rdfs:subClassOf obo:CL_0000015, obo:CL_0000300, obo:CL_0000548 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000015 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001375 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009566 ] ) ] . obo:CL_0000411 obo:IAO_0000115 "An epithelial cell of the hypodermis of Caenorhabditis." ; oboInOwl:hasBroadSynonym "roundworm hypodermal cell" ; oboInOwl:hasDbXref "WBbt:0007846" ; a owl:Class ; rdfs:comment "This term was originally added to CL for parity with the Worm anatomy ontology, which is dedicated to C elegans. It is not clear if it makes sense to try and generalize the concept and include in CL, and this term may be obsoleted in future. Note there is no similarity to the hypodermis in vertebrates." ; rdfs:label "Caenorhabditis hypodermal cell" ; rdfs:subClassOf obo:CL_0000076, obo:CL_0000228, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_6237 ] . obo:CL_0000412 obo:IAO_0000115 "A cell whose nucleus, or nuclei, each contain more than two haploid genomes." ; a owl:Class ; rdfs:label "polyploid cell" ; rdfs:subClassOf obo:CL_0000003 . obo:CL_0000413 obo:IAO_0000115 "A cell whose nucleus contains a single haploid genome." ; a owl:Class ; rdfs:label "haploid cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001375 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001375 ] ) ] . obo:CL_0000417 a owl:Class ; rdfs:label "endopolyploid cell" ; rdfs:subClassOf obo:CL_0000412 . obo:CL_0000447 a owl:Class ; rdfs:label "carbohydrate secreting cell" ; rdfs:subClassOf obo:CL_0000151 . obo:CL_0000451 obo:IAO_0000115 "A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative)." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0002042", "CALOHA:TS-0194", "FMA:83036", "MESH:D003713" ; oboInOwl:hasRelatedSynonym "interdigitating cell", "veiled cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "dendritic cell" ; rdfs:subClassOf obo:CL_0000145, obo:CL_0000842, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0042613 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001003 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001816 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0045580 ] ; owl:disjointWith obo:CL_0000542 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000738 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0042613 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001003 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001407 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001816 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0002504 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0019882 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0045580 ] ) ] . obo:CL_0000457 a owl:Class ; rdfs:label "biogenic amine secreting cell" ; rdfs:subClassOf obo:CL_0000151 . obo:CL_0000458 obo:IAO_0000115 "A cell type that secretes 5-Hydroxytryptamine (serotonin)." ; oboInOwl:hasExactSynonym "5-HT secreting cell", "5-Hydroxytryptamine secreting cell" ; a owl:Class ; rdfs:label "serotonin secreting cell" ; rdfs:subClassOf obo:CL_0000457, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001820 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001820 ] ) ] . obo:CL_0000459 obo:IAO_0000115 "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme." ; oboInOwl:hasExactSynonym "noradrenaline secreting cell", "norepinephrin secreting cell", "norepinephrine secreting cell" ; a owl:Class ; rdfs:label "noradrenergic cell" ; rdfs:subClassOf obo:CL_0000457, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048243 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048243 ] ) ] . obo:CL_0000488 obo:IAO_0000115 "A photoreceptor cell that detects visible light." ; a owl:Class ; rdfs:label "visible light photoreceptor cell" ; rdfs:subClassOf obo:CL_0000210, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000210 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009584 ] ) ] . obo:CL_0000498 obo:IAO_0000115 "An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS)." ; oboInOwl:hasDbXref "FMA:84776" ; a owl:Class ; rdfs:label "inhibitory interneuron" ; rdfs:subClassOf obo:CL_0000099 . obo:CL_0000499 obo:IAO_0000115 "A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0002064", "FMA:83624" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "stromal cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0002320, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000134 ] . obo:CL_0000502 obo:IAO_0000115 "A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin." ; oboInOwl:hasDbXref "FMA:62935" ; oboInOwl:hasExactSynonym "D cell" ; a owl:Class ; rdfs:label "type D enteroendocrine cell" ; rdfs:subClassOf obo:CL_0000164, obo:CL_0000172 . obo:CL_0000506 obo:IAO_0000115 "An endorphine cell that secretes enkephalin." ; a owl:Class ; rdfs:label "enkephalin secreting cell" ; rdfs:subClassOf obo:CL_0000507 . obo:CL_0000507 obo:IAO_0000115 "A peptide hormone secreting cell that secretes endorphin." ; a owl:Class ; rdfs:label "endorphin secreting cell" ; rdfs:subClassOf obo:CL_0000167 . obo:CL_0000508 obo:IAO_0000115 "An endocrine cell found in the pyloric gland mucosa (antral mucosa) of the stomach of mammals and responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli." ; oboInOwl:hasDbXref "BTO:0004108", "FMA:67609" ; oboInOwl:hasExactSynonym "G cell" ; a owl:Class ; rdfs:label "type G enteroendocrine cell" ; rdfs:subClassOf obo:CL_0000164, obo:CL_0000506, obo:CL_0000509, obo:CL_0002180, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004997 ] . obo:CL_0000509 obo:IAO_0000115 "A peptide hormone secreting cell that secretes gastrin." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "gastrin secreting cell" ; rdfs:subClassOf obo:CL_0000167 . obo:CL_0000511 obo:IAO_0000115 "A peptide hormone secreting cell that secretes androgen binding protein." ; a owl:Class ; rdfs:label "androgen binding protein secreting cell" ; rdfs:subClassOf obo:CL_0000154 . obo:CL_0000513 obo:IAO_0000115 "A precursor cell destined to differentiate into cardiac muscle cell." ; oboInOwl:hasDbXref "FMA:84797" ; oboInOwl:hasExactSynonym "cardiac muscle progenitor cell", "cardiomyocyte progenitor cell" ; a owl:Class ; rdfs:label "cardiac muscle myoblast" ; rdfs:subClassOf obo:CL_0002494, obo:CL_0010021, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000056 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001133 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0000746 ] ) ] . obo:CL_0000514 obo:IAO_0000115 "A precursor cell destined to differentiate into smooth muscle myocytes." ; oboInOwl:hasDbXref "FMA:84798" ; oboInOwl:hasExactSynonym "myoblast, smooth muscle" ; oboInOwl:hasRelatedSynonym "satellite cell" ; a owl:Class ; rdfs:label "smooth muscle myoblast" ; rdfs:subClassOf obo:CL_0000056, [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0000192 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000056 [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0000192 ] ) ] . obo:CL_0000515 obo:IAO_0000115 "A myoblast that differentiates into skeletal muscle fibers." ; oboInOwl:hasDbXref "FMA:84799" ; oboInOwl:hasExactSynonym "skeletal myoblast" ; a owl:Class ; rdfs:label "skeletal muscle myoblast" ; rdfs:subClassOf obo:CL_0000056, obo:CL_0011026, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000355 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0008002 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000056 [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0008002 ] ) ] . obo:CL_0000521 a owl:Class ; rdfs:label "fungal cell" ; rdfs:subClassOf obo:CL_0000255, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:disjointWith obo:CL_0000548 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ) ] . obo:CL_0000525 obo:IAO_0000115 "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:83043" ; oboInOwl:hasExactSynonym "plasmidotrophoblast", "syncytial trophoblast", "syntrophoblast" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "syncytiotrophoblast cell" ; rdfs:subClassOf obo:CL_0000228, obo:CL_2000060 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000351 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001908 ] ) ] . obo:CL_0000526 obo:IAO_0000115 "A neuron which conveys sensory information centrally from the periphery." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:87653" ; oboInOwl:hasExactSynonym "input neuron" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "afferent neuron" ; rdfs:subClassOf obo:CL_0000540 . obo:CL_0000527 obo:IAO_0000115 "A neuron which sends impulses peripherally to activate muscles or secretory cells." ; oboInOwl:hasExactSynonym "output neuron" ; a owl:Class ; rdfs:label "efferent neuron" ; rdfs:subClassOf obo:CL_0000540 . obo:CL_0000530 a owl:Class ; rdfs:label "primary neuron" ; rdfs:subClassOf obo:CL_0000540 . obo:CL_0000531 a owl:Class ; rdfs:label "primary sensory neuron" ; rdfs:subClassOf obo:CL_0000101, obo:CL_0000530 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000101 obo:CL_0000530 ) ] . obo:CL_0000540 obo:IAO_0000115 "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000938", "CALOHA:TS-0683", "FBbt:00005106", "FMA:54527", "VHOG:0001483", "WBbt:0003679" ; oboInOwl:hasExactSynonym "nerve cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ; rdfs:label "neuron" ; rdfs:subClassOf obo:CL_0000393, obo:CL_0000404, obo:CL_0002319, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0019226 ] . obo:CL_0000542 obo:IAO_0000115 "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000775", "CALOHA:TS-0583", "FMA:62863", "MESH:D008214", "VHOG:0001535" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)" ; rdfs:label "lymphocyte" ; rdfs:subClassOf obo:CL_0000842, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017500 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017505 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0000792 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000051 ] ; owl:disjointWith obo:CL_0000766 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000738 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017500 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017505 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0000792 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001407 ] ) ] . obo:CL_0000547 obo:IAO_0000115 "An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers." ; oboInOwl:hasDbXref "FMA:83518" ; oboInOwl:hasExactSynonym "rubriblast" ; oboInOwl:hasRelatedSynonym "pronormoblast" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:label "proerythroblast" ; rdfs:subClassOf obo:CARO_0000006, obo:CL_0000764, obo:CL_0002242, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017503 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017505 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005730 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000038 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000764 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017503 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017505 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005730 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002505 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ] ) ] . obo:CL_0000548 obo:IAO_0000115 "A native cell that is part of some Metazoa." ; oboInOwl:hasExactSynonym "metazoan cell" ; oboInOwl:inSubset ubprop:_upper_level ; a owl:Class ; rdfs:label "animal cell" ; rdfs:subClassOf obo:CL_0000255, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ] ) ] . obo:CL_0000549 obo:IAO_0000115 "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers." ; oboInOwl:hasDbXref "FMA:83505" ; oboInOwl:hasExactSynonym "basophilic normoblast", "early erythroblast", "early normoblast", "prorubricyte" ; a owl:Class ; rdfs:label "basophilic erythroblast" ; rdfs:subClassOf obo:CARO_0000006, obo:CL_0000765, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017503 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0000792 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000765 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017503 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0000792 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ] ) ] . obo:CL_0000550 obo:IAO_0000115 "A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers." ; oboInOwl:hasDbXref "FMA:83506" ; oboInOwl:hasExactSynonym "intermediate erythroblast", "intermediate normoblast", "polychromatic erythroblast", "polychromatic normoblast", "polychromatophilic normoblast", "rubricyte" ; a owl:Class ; rdfs:label "polychromatophilic erythroblast" ; rdfs:subClassOf obo:CARO_0000006, obo:CL_0000765, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017504 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0000792 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000549 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000765 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017504 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0000792 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ] ) ] . obo:CL_0000552 obo:IAO_0000115 "The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated." ; oboInOwl:hasDbXref "FMA:84646" ; oboInOwl:hasExactSynonym "acidophilic erythroblast", "eosinophilic erythroblast", "late erythoblast", "orthochromatic normoblast", "pyknotic eto enrythroblast" ; a owl:Class ; rdfs:label "orthochromatic erythroblast" ; rdfs:subClassOf obo:CL_0000765, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017502 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:GO_0030263 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000550 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000765 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CL_0017502 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:GO_0030263 ] ) ] . obo:CL_0000553 obo:IAO_0000115 "The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative)." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0001164", "CALOHA:TS-0610", "FMA:84235", "MESH:D055016" ; oboInOwl:hasExactSynonym "CFU-Meg", "Meg-CFC", "MkP", "colony-forming unit-megakaryocyte", "megacaryoblast", "megacaryocyte progenitor cell", "megakaryoblast", "megakaryocytic progenitor cell" ; oboInOwl:hasRelatedSynonym "promegacaryocyte", "promegakaryocyte" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative." ; rdfs:label "megakaryocyte progenitor cell" ; rdfs:subClassOf obo:CL_0000763, obo:CL_0000839, [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002981 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000050 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007113 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030219 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000839 [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002981 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007113 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030219 ] ) ] . obo:CL_0000556 obo:IAO_0000115 "A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000843", "CALOHA:TS-0611", "FMA:83555" ; oboInOwl:hasExactSynonym "megacaryocyte", "megalocaryocyte", "megalokaryocyte" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim, core:human_reference_atlas ; a owl:Class ; rdfs:comment "Megakaryocytes are reportedly CD181-positive and CD182-positive." ; rdfs:label "megakaryocyte" ; rdfs:subClassOf obo:CL_0000763, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001393 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000553 ] ; owl:disjointWith obo:CL_0000764 . obo:CL_0000558 obo:IAO_0000115 "An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds." ; oboInOwl:hasDbXref "BTO:0001173", "CALOHA:TS-0864", "MESH:D012156" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:label "reticulocyte" ; rdfs:subClassOf obo:CARO_0000006, obo:CL_0000764, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000552 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0071971 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000764 [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0071971 ] ) ] . obo:CL_0000562 obo:IAO_0000115 "An erythrocyte having a nucleus." ; oboInOwl:hasBroadSynonym "RBC", "red blood cell" ; a owl:Class ; rdfs:label "nucleate erythrocyte" ; rdfs:subClassOf obo:CL_0000232, obo:CL_0002242, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002421 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000232 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002505 ] ) ] . obo:CL_0000566 obo:IAO_0000115 "A mesenchymal stem cell capable of developing into blood vessel endothelium." ; oboInOwl:hasExactSynonym "angioblast", "chondroplast" ; a owl:Class ; rdfs:comment "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive." ; rdfs:label "angioblastic mesenchymal cell" ; rdfs:subClassOf obo:CARO_0000006, obo:CL_0000134, obo:CL_0011026, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001444 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000002112 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000016043 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000134 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000134 [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001444 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000002112 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000016043 ] ) ] . obo:CL_0000569 obo:IAO_0000115 "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field." ; a owl:Class ; rdfs:label "cardiac mesenchymal cell" ; rdfs:subClassOf obo:CL_0008019, obo:CL_2000073, [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0002494 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0008019 [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0002494 ] ) ] . obo:CL_0000573 obo:IAO_0000115 "One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0001036", "CALOHA:TS-0866", "FMA:67748" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "retinal cone cell" ; rdfs:subClassOf obo:CL_0010009, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002672 ] . obo:CL_0000575 obo:IAO_0000115 "An epithelial cell of the cornea." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0004298", "CALOHA:TS-0173", "FMA:70551" ; oboInOwl:hasExactSynonym "epithelial cell of cornea" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "corneal epithelial cell" ; rdfs:subClassOf obo:CL_0000076, obo:CL_0002159, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001772 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000076 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001772 ] ) ] . obo:CL_0000586 obo:IAO_0000115 "The reproductive cell in multicellular organisms." ; oboInOwl:hasDbXref "BTO:0000535", "VHOG:0001534", "WBbt:0006796" ; a owl:Class ; rdfs:label "germ cell" ; rdfs:subClassOf obo:CL_0000039, [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0009566 ] . obo:CL_0000593 obo:IAO_0000115 "A steroid hormone secreting cell that secretes androgen." ; a owl:Class ; rdfs:label "androgen secreting cell" ; rdfs:subClassOf obo:CL_0000174, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0035935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0035935 ] ) ] . obo:CL_0000595 obo:IAO_0000115 "An erythrocyte lacking a nucleus." ; oboInOwl:hasBroadSynonym "RBC", "red blood cell" ; a owl:Class ; rdfs:label "enucleate erythrocyte" ; rdfs:subClassOf obo:CL_0000225, obo:CL_0000232, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002422 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000232 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001405 ] ) ] . obo:CL_0000604 obo:IAO_0000115 "One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0001024", "CALOHA:TS-0870", "FMA:67747" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "retinal rod cell" ; rdfs:subClassOf obo:CL_0010009, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002672 ] . obo:CL_0000617 obo:IAO_0000115 "A neuron that uses GABA as a vesicular neurotransmitter" ; oboInOwl:hasDbXref "FBbt:00007228", "FMA:84788", "MESH:D059330", "WBbt:0005190" ; oboInOwl:hasExactSynonym "GABA-ergic neuron" ; a owl:Class ; rdfs:label "GABAergic neuron" ; rdfs:subClassOf obo:CL_0000161, obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0061534 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0061534 ] ) ] . obo:CL_0000618 a owl:Class ; rdfs:label "sheath cell" ; rdfs:subClassOf obo:CL_0000075 . obo:CL_0000622 obo:IAO_0000115 "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus)." ; oboInOwl:hasDbXref "FMA:83625", "MESH:D061354" ; oboInOwl:hasExactSynonym "acinic cell", "acinous cell" ; a owl:Class ; rdfs:label "acinar cell" ; rdfs:subClassOf obo:CL_0000150, obo:CL_0000154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0009842 ] . obo:CL_0000630 obo:IAO_0000115 "A cell whose primary function is to support other cell types." ; oboInOwl:hasDbXref "BTO:0002315" ; oboInOwl:hasExactSynonym "supportive cell" ; a owl:Class ; rdfs:label "supporting cell" ; rdfs:subClassOf obo:CL_0000003 . obo:CL_0000656 obo:IAO_0000115 "A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes." ; oboInOwl:hasDbXref "BTO:0001115", "CALOHA:TS-2194", "FMA:72292" ; a owl:Class ; rdfs:label "primary spermatocyte" ; rdfs:subClassOf obo:CL_0000017, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001394 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007140 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000017 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001394 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007140 ] ) ] . obo:CL_0000657 obo:IAO_0000115 "One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids." ; oboInOwl:hasDbXref "BTO:0000709", "CALOHA:TS-2195", "FBbt:00004941", "FMA:72293" ; a owl:Class ; rdfs:label "secondary spermatocyte" ; rdfs:subClassOf obo:CL_0000017, obo:CL_0000413, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007142 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000017 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001375 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007142 ] ) ] . obo:CL_0000667 obo:IAO_0000115 "An extracellular matrix secreting cell that secretes collagen." ; a owl:Class ; rdfs:label "collagen secreting cell" ; rdfs:subClassOf obo:CL_0000327 . obo:CL_0000670 obo:IAO_0000115 "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." ; oboInOwl:hasDbXref "FMA:70567" ; oboInOwl:hasExactSynonym "gonocyte", "primitive germ cell" ; a owl:Class ; rdfs:label "primordial germ cell" ; rdfs:subClassOf obo:CL_0000039, obo:CL_0000219, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000922 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000039 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000922 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048870 ] ) ] . obo:CL_0000675 obo:IAO_0000115 "A mature sexual reproductive cell of the female germline." ; a owl:Class ; rdfs:label "female gamete" ; rdfs:subClassOf obo:CL_0000021, obo:CL_0000300 . obo:CL_0000680 obo:IAO_0000115 "A non-terminally differentiated cell that is capable of developing into a muscle cell." ; a owl:Class ; rdfs:label "muscle precursor cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000055, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000222 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0000187 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0011115 [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:CL_0000696 obo:IAO_0000115 "A cell that stores and secretes pancreatic polypeptide hormone." ; oboInOwl:hasDbXref "FMA:62938", "FMA:83409" ; oboInOwl:hasExactSynonym "type F enteroendocrine cell" ; a owl:Class ; rdfs:label "PP cell" ; rdfs:subClassOf obo:CL_0000164, obo:CL_0000167 . obo:CL_0000700 obo:IAO_0000115 "A neuron that releases dopamine as a neurotransmitter." ; oboInOwl:hasDbXref "BTO:0004032", "FBbt:00005131", "FMA:84787", "MESH:D059290", "WBbt:0006746" ; oboInOwl:hasExactSynonym "dopaminergic cell" ; a owl:Class ; rdfs:label "dopaminergic neuron" ; rdfs:subClassOf obo:CL_0000151, obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0061527 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0061527 ] ) ] . obo:CL_0000710 obo:IAO_0000115 "Epithelial cells derived from neural plate and neural crest." ; oboInOwl:hasBroadSynonym "neuroepithelial cell" ; oboInOwl:hasDbXref "BTO:0004301", "FMA:70557" ; a owl:Class ; rdfs:comment "The term \"neuroepithelial cell\" is used to describe both this cell type and sensory epithelial cell (CL:0000098)." ; rdfs:label "neurecto-epithelial cell" ; rdfs:subClassOf obo:CL_0000075, obo:CL_0002077, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002077 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000133 ] ) ] . obo:CL_0000723 obo:IAO_0000115 "A stem cell that can give rise to cell types of the body other than those of the germ-line." ; oboInOwl:hasDbXref "CALOHA:TS-2086", "FMA:63368", "MESH:D053687" ; a owl:Class ; rdfs:label "somatic stem cell" ; rdfs:subClassOf obo:CL_0000034, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048103 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000034 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048103 ] ) ] . obo:CL_0000737 obo:IAO_0000115 "Muscle cell which has as its direct parts myofilaments organized into sarcomeres." ; oboInOwl:hasDbXref "BTO:0002916", "CALOHA:TS-2157", "FMA:86936" ; a owl:Class ; rdfs:label "striated muscle cell" ; rdfs:subClassOf obo:CL_0000187, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030017 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001410 ] ; owl:disjointWith obo:CL_0008000 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000187 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001410 ] ) ] . obo:CL_0000738 obo:IAO_0000115 "An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ; oboInOwl:hasDbXref "BTO:0000751", "CALOHA:TS-0549", "FMA:62852", "MESH:D007962" ; oboInOwl:hasExactSynonym "leucocyte", "white blood cell" ; oboInOwl:hasRelatedSynonym "immune cell" ; a owl:Class ; rdfs:label "leukocyte" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000219, obo:CL_0000988, obo:CL_0002242, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002405 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000037 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000988 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002505 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001667 ] ) ] . obo:CL_0000740 obo:IAO_0000115 "The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0001800", "FMA:67765", "MESH:D012165" ; oboInOwl:hasExactSynonym "RGC", "gangliocyte", "ganglion cell of retina" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "retinal ganglion cell" ; rdfs:subClassOf obo:CL_0000117, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0000966 ] . obo:CL_0000746 obo:IAO_0000115 "Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasAlternativeId "FMA:83808" ; oboInOwl:hasBroadSynonym "cardiocyte" ; oboInOwl:hasDbXref "BTO:0001539", "CALOHA:TS-0115", "FMA:14067", "MESH:D032383" ; oboInOwl:hasExactSynonym "cardiac muscle fiber", "cardiac myocyte", "cardiomyocyte", "heart muscle cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction." ; rdfs:label "cardiac muscle cell" ; rdfs:subClassOf obo:CL_0000737, obo:CL_0002494, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002478 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:GO_0060047 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000513 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000187 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007100 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002478 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:GO_0060047 ] ) ] . obo:CL_0000763 obo:IAO_0000115 "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0001441", "CALOHA:TS-0647", "MESH:D022423" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "myeloid cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000988, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000988 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000049 ] ) ] . obo:CL_0000764 obo:IAO_0000115 "A immature or mature cell in the lineage leading to and including erythrocytes." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "CALOHA:TS-0290", "FMA:62845", "FMA:83516" ; oboInOwl:hasExactSynonym "erythropoietic cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "Note that in FMA erythropoietic cells are types of nucleated erythrocytes and thus don't include erythrocytes." ; rdfs:label "erythroid lineage cell" ; rdfs:subClassOf obo:CL_0000763 . obo:CL_0000765 obo:IAO_0000115 "A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers." ; oboInOwl:hasDbXref "BTO:0001571", "CALOHA:TS-0289", "FMA:83504", "MESH:D004900" ; oboInOwl:hasExactSynonym "normoblast" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:label "erythroblast" ; rdfs:subClassOf obo:CL_0000764, obo:CL_0011026, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005634 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030045 ; owl:someValuesFrom obo:GO_0005730 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000547 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030218 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000764 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030045 ; owl:someValuesFrom obo:GO_0005730 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030218 ] ) ] . obo:CL_0000766 obo:IAO_0000115 "A cell of the monocyte, granulocyte, or mast cell lineage." ; a owl:Class ; rdfs:label "myeloid leukocyte" ; rdfs:subClassOf obo:CL_0000738, obo:CL_0000763 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000738 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000049 ] ) ] . obo:CL_0000827 obo:IAO_0000115 "A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage." ; oboInOwl:hasExactSynonym "pro-T lymphocyte", "progenitor T cell" ; oboInOwl:hasNarrowSynonym "DN1 cell", "DN1 thymocyte", "TN1 cell" ; a owl:Class ; rdfs:label "pro-T cell" ; rdfs:subClassOf obo:CL_0000838, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000051 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030217 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000838 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030217 ] ) ] . obo:CL_0000837 obo:IAO_0000115 "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000725", "CALOHA:TS-0448" ; oboInOwl:hasExactSynonym "MPP", "hemopoietic progenitor cell" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim, core:human_reference_atlas ; a owl:Class ; rdfs:comment "Markers differ between mouse and human." ; rdfs:label "hematopoietic multipotent progenitor cell" ; rdfs:subClassOf obo:CARO_0000006, obo:CL_0008001, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001869 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002981 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001402 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001003 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000037 ] ; owl:disjointWith obo:CL_0002032 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000988 [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001869 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002981 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001402 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001003 ] ) ] . obo:CL_0000838 obo:IAO_0000115 "A progenitor cell restricted to the lymphoid lineage." ; oboInOwl:hasBroadSynonym "lymphoid progenitor cell" ; oboInOwl:hasDbXref "BTO:0004731", "CALOHA:TS-2025", "FMA:70338" ; a owl:Class ; rdfs:comment "Note that this is a class of cell types, not an identified single cell type." ; rdfs:label "lymphoid lineage restricted progenitor cell" ; rdfs:subClassOf obo:CL_0002031, obo:CL_0011026, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030098 ] ; owl:disjointWith obo:CL_0000839 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002031 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030098 ] ) ] . obo:CL_0000839 obo:IAO_0000115 "A progenitor cell restricted to the myeloid lineage." ; oboInOwl:hasBroadSynonym "myeloid progenitor cell" ; oboInOwl:hasDbXref "BTO:0004730", "CALOHA:TS-2099", "FMA:70339" ; a owl:Class ; rdfs:comment "Note that this is a class of cell types, not an identified single cell type." ; rdfs:label "myeloid lineage restricted progenitor cell" ; rdfs:subClassOf obo:CL_0002031, obo:CL_0011026, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030099 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002031 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030099 ] ) ] . obo:CL_0000842 obo:IAO_0000115 "A leukocyte with a single non-segmented nucleus in the mature form." ; oboInOwl:hasDbXref "BTO:0000878", "CALOHA:TS-0768", "FMA:86713" ; oboInOwl:hasExactSynonym "mononuclear leukocyte" ; oboInOwl:hasNarrowSynonym "peripheral blood mononuclear cell" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:label "mononuclear cell" ; rdfs:subClassOf obo:CL_0000226, obo:CL_0000738 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000738 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001407 ] ) ] . obo:CL_0000850 obo:IAO_0000115 "A neuron that releases serotonin as a neurotransmitter." ; oboInOwl:hasDbXref "FBbt:00005133", "MESH:D059326", "WBbt:0006837" ; oboInOwl:hasExactSynonym "5-HT neuron", "5-hydroxytryptamine neuron" ; oboInOwl:hasRelatedSynonym "serotinergic neuron" ; a owl:Class ; rdfs:label "serotonergic neuron" ; rdfs:subClassOf obo:CL_0000458, obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0060096 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0060096 ] ) ] . obo:CL_0000988 obo:IAO_0000115 "A cell of a hematopoietic lineage." ; oboInOwl:hasDbXref "BTO:0000574", "CALOHA:TS-2017", "FMA:70366", "FMA:83598" ; oboInOwl:hasExactSynonym "haematopoietic cell", "haemopoietic cell", "hemopoietic cell" ; a owl:Class ; rdfs:label "hematopoietic cell" ; rdfs:subClassOf obo:CL_0002371 . obo:CL_0001035 obo:IAO_0000115 "A connective tissue cell found in bone." ; terms:contributor ; oboInOwl:creation_date "2011-11-16T04:28:16Z" ; a owl:Class ; rdfs:label "bone cell" ; rdfs:subClassOf obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001474 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000548 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001474 ] ) ] . obo:CL_0001060 obo:IAO_0000115 "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers." ; terms:contributor ; oboInOwl:creation_date "2010-01-06T03:43:27Z" ; a owl:Class ; rdfs:label "hematopoietic oligopotent progenitor cell, lineage-negative" ; rdfs:subClassOf obo:CL_0002032, [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002981 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002032 [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002981 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001401 ] ) ] . obo:CL_0001061 obo:IAO_0000115 "A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models." ; terms:contributor ; terms:date "2017-01-30T18:53:32Z"^^xsd:dateTime ; oboInOwl:hasDbXref "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12913" ; a owl:Class ; rdfs:comment "https://github.com/obophenotype/cell-ontology/issues/448" ; rdfs:label "abnormal cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000460 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] . obo:CL_0001065 obo:IAO_0000115 "A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; terms:date "2017-01-30T20:20:48Z"^^xsd:dateTime ; oboInOwl:inSubset cl:blood_and_immune_upper_slim, core:human_reference_atlas ; a owl:Class ; rdfs:label "innate lymphoid cell" ; rdfs:subClassOf obo:CL_0000542, [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001816 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0045087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000542 [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001816 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0045087 ] ) ] . obo:CL_0001066 obo:IAO_0000115 "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative)." ; oboInOwl:hasDbXref "BTO:0004911" ; oboInOwl:hasRelatedSynonym "BFU-E", "CFU-E", "blast forming unit erythroid", "burst forming unit erythroid", "colony forming unit erythroid", "erythroid stem cell" ; a owl:Class ; rdfs:label "erythroid progenitor cell, mammalian" ; rdfs:subClassOf obo:CARO_0000006, obo:CL_0000038, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ], [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030218 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000038 [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001002 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001004 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001012 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001020 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001024 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001083 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001084 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001289 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001839 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000001889 ] [ a owl:Restriction ; owl:onProperty obo:CL_4030046 ; owl:someValuesFrom obo:PR_000002978 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002104 ; owl:someValuesFrom obo:PR_000001945 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030218 ] ) ] . obo:CL_0001082 obo:IAO_0000115 "An innate lyphoid cell with an immature phenotype." ; oboInOwl:hasExactSynonym "immature ILC" ; a owl:Class ; rdfs:label "immature innate lymphoid cell" ; rdfs:subClassOf obo:CL_0001065, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0001065 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001501 ] ) ] . obo:CL_0002031 obo:IAO_0000115 "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells." ; terms:contributor ; oboInOwl:creation_date "2010-01-06T03:43:20Z" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:label "hematopoietic lineage restricted progenitor cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0008001, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001400 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002032 ] ; owl:disjointWith obo:CL_0002032 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000988 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001400 ] ) ] . obo:CL_0002032 obo:IAO_0000115 "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities." ; terms:contributor ; oboInOwl:creation_date "2010-01-06T03:43:27Z" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:comment "This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060)." ; rdfs:label "hematopoietic oligopotent progenitor cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0008001, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001401 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000988 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001401 ] ) ] . obo:CL_0002064 obo:IAO_0000115 "A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-06-24T03:16:29Z" ; oboInOwl:hasDbXref "BTO:0000028", "CALOHA:TS-0737", "FMA:63032" ; oboInOwl:hasExactSynonym "acinar cell of pancreas" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "pancreatic acinar cell" ; rdfs:subClassOf obo:CL_0000622, obo:CL_1001599, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001263 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0042589 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000622 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001263 ] ) ] . obo:CL_0002067 obo:IAO_0000115 "An enteroendocrine cell that produces glucagon." ; terms:contributor ; oboInOwl:creation_date "2010-09-10T10:48:54Z" ; oboInOwl:hasDbXref "FMA:62939" ; a owl:Class ; rdfs:label "type A enteroendocrine cell" ; rdfs:subClassOf obo:CL_0000164, obo:CL_0000170 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000164 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0070091 ] ) ] . obo:CL_0002068 obo:IAO_0000115 "Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-06-28T08:36:15Z" ; oboInOwl:hasDbXref "BTO:0001032", "FMA:14146" ; oboInOwl:hasExactSynonym "Purkinje cell fiber", "Purkinje muscle cell", "myocytus conducens cardiacus" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "Purkinje myocyte" ; rdfs:subClassOf obo:CL_0002086 . obo:CL_0002072 obo:IAO_0000115 "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery." ; terms:contributor ; oboInOwl:creation_date "2010-06-29T11:41:37Z" ; oboInOwl:hasBroadSynonym "pacemaker cell" ; oboInOwl:hasDbXref "BTO:0004190", "FMA:67101" ; oboInOwl:hasExactSynonym "P cell", "cardiac pacemaker cell", "myocytus nodalis" ; a owl:Class ; rdfs:label "nodal myocyte" ; rdfs:subClassOf obo:CL_0002086 . obo:CL_0002073 obo:IAO_0000115 "Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes." ; terms:contributor ; oboInOwl:creation_date "2010-06-29T02:39:32Z" ; oboInOwl:hasDbXref "FMA:67142" ; a owl:Class ; rdfs:label "transitional myocyte" ; rdfs:subClassOf obo:CL_0002086 . obo:CL_0002074 obo:IAO_0000115 "The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides)." ; terms:contributor ; oboInOwl:creation_date "2010-06-29T11:50:47Z" ; oboInOwl:hasDbXref "FMA:67111" ; a owl:Class ; rdfs:label "myocardial endocrine cell" ; rdfs:subClassOf obo:CL_0000163, obo:CL_0002086 . obo:CL_0002076 obo:IAO_0000115 "An epithelial cell derived from endoderm." ; terms:contributor ; oboInOwl:creation_date "2010-06-29T03:38:14Z" ; oboInOwl:hasDbXref "FMA:69075" ; a owl:Class ; rdfs:label "endo-epithelial cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000066, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000223 ] . obo:CL_0002077 obo:IAO_0000115 "An epithelial cell derived from ectoderm." ; terms:contributor ; oboInOwl:creation_date "2010-06-29T03:38:22Z" ; oboInOwl:hasDbXref "FMA:69074" ; a owl:Class ; rdfs:label "ecto-epithelial cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000066, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000221 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000221 ] ) ] . obo:CL_0002078 obo:IAO_0000115 "Epithelial cell derived from mesoderm or mesenchyme." ; terms:contributor ; oboInOwl:creation_date "2010-06-29T03:49:14Z" ; oboInOwl:hasDbXref "FMA:69076" ; oboInOwl:hasExactSynonym "epithelial mesenchymal cell" ; a owl:Class ; rdfs:label "meso-epithelial cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000066, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000222 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000222 ] ) ] . obo:CL_0002079 obo:IAO_0000115 "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-06-30T08:49:43Z" ; oboInOwl:hasDbXref "FMA:63099" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "pancreatic ductal cell" ; rdfs:subClassOf obo:CL_0000069, obo:CL_1001433, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001064 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0015106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000083 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001064 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0015106 ] ) ] . obo:CL_0002080 obo:IAO_0000115 "A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-06-30T08:49:52Z" ; oboInOwl:hasDbXref "FMA:62455" ; oboInOwl:hasExactSynonym "centroacinar cell of Langerhans", "pancreatic centroacinar cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "pancreatic centro-acinar cell" ; rdfs:subClassOf obo:CL_1001433, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001263 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0015106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000083 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001263 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0015106 ] ) ] . obo:CL_0002086 obo:IAO_0000115 "A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart." ; terms:contributor ; oboInOwl:creation_date "2010-07-21T01:33:38Z" ; oboInOwl:hasDbXref "FMA:67968" ; a owl:Class ; rdfs:label "specialized cardiac myocyte" ; rdfs:subClassOf obo:CL_0000746 . obo:CL_0002087 obo:IAO_0000115 "A leukocyte that lacks granules." ; terms:contributor ; oboInOwl:creation_date "2010-07-22T11:30:33Z" ; oboInOwl:hasDbXref "FMA:62855" ; oboInOwl:hasExactSynonym "agranular leukocyte" ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:label "nongranular leukocyte" ; rdfs:subClassOf obo:CL_0000738, [ a owl:Restriction ; owl:onProperty obo:CL_4030045 ; owl:someValuesFrom obo:GO_0030141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000738 [ a owl:Restriction ; owl:onProperty obo:CL_4030045 ; owl:someValuesFrom obo:GO_0030141 ] ) ] . obo:CL_0002088 obo:IAO_0000115 "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-07-22T03:26:00Z" ; oboInOwl:hasDbXref "BTO:0003914", "FMA:86573" ; oboInOwl:hasExactSynonym "ICC", "intestinal pacemaker cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "Some argue this cell type is of mesenchymal origin." ; rdfs:label "interstitial cell of Cajal" ; rdfs:subClassOf obo:CL_0000710, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0043134 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000710 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0043134 ] ) ] . obo:CL_0002092 obo:IAO_0000115 "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells." ; terms:contributor ; oboInOwl:creation_date "2010-07-22T04:48:15Z" ; oboInOwl:hasDbXref "BTO:0004850", "FMA:83621", "MESH:D001854" ; a owl:Class ; rdfs:comment "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense." ; rdfs:label "bone marrow cell" ; rdfs:subClassOf obo:CL_0001035, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002371 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0001035 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002371 ] ) ] . obo:CL_0002095 obo:IAO_0000115 "A cell in the hilum of the ovary that produces androgens." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-08-23T11:18:18Z" ; oboInOwl:hasDbXref "FMA:18710" ; oboInOwl:hasExactSynonym "hilar cell of ovary" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "hilus cell of ovary" ; rdfs:subClassOf obo:CL_0000593, obo:CL_0002132 . obo:CL_0002132 obo:IAO_0000115 "A stomal cell of the ovary" ; terms:contributor ; oboInOwl:creation_date "2010-08-23T12:10:31Z" ; oboInOwl:hasDbXref "FMA:72299" ; oboInOwl:hasExactSynonym "ovarian stromal cell" ; a owl:Class ; rdfs:label "stromal cell of ovary" ; rdfs:subClassOf obo:CL_0000499, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000992 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000499 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000992 ] ) ] . obo:CL_0002139 obo:IAO_0000115 "An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels." ; terms:contributor ; oboInOwl:creation_date "2010-08-24T02:06:40Z" ; oboInOwl:hasDbXref "BTO:0001854", "CALOHA:TS-1106", "FMA:67755" ; oboInOwl:hasExactSynonym "vascular endothelial cell" ; oboInOwl:hasNarrowSynonym "cubodial endothelial cell of vascular tree" ; a owl:Class ; rdfs:comment "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, TAL1-positive." ; rdfs:label "endothelial cell of vascular tree" ; rdfs:subClassOf obo:CL_0000115 . obo:CL_0002144 obo:IAO_0000115 "An endothelial cell found in capillaries." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-08-24T10:15:00Z" ; oboInOwl:hasDbXref "BTO:0004956", "CALOHA:TS-0112", "FMA:67756" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "capillary endothelial cell" ; rdfs:subClassOf obo:CL_2000008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000071 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001915 ] ) ] . obo:CL_0002145 obo:IAO_0000115 "A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-08-24T03:38:29Z" ; oboInOwl:hasDbXref "FMA:70542" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "ciliated columnar cell of tracheobronchial tree" ; rdfs:subClassOf obo:CL_0002202, obo:CL_0005012, obo:CL_4030034, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002209 ] . obo:CL_0002149 obo:IAO_0000115 "An epithelial cell of the uterus." ; terms:contributor ; oboInOwl:creation_date "2010-08-24T10:45:54Z" ; oboInOwl:hasDbXref "FMA:256161" ; a owl:Class ; rdfs:label "epithelial cell of uterus" ; rdfs:subClassOf obo:CL_0002076, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000995 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002076 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000995 ] ) ] . obo:CL_0002159 obo:IAO_0000115 "Epithelial cells derived from general body ectoderm and ectoderm placodes." ; terms:contributor ; oboInOwl:creation_date "2010-08-26T08:31:08Z" ; oboInOwl:hasDbXref "FMA:70556" ; a owl:Class ; rdfs:label "general ecto-epithelial cell" ; rdfs:subClassOf obo:CL_0002077 . obo:CL_0002178 obo:IAO_0000115 "An epithelial cell found in the lining of the stomach." ; terms:contributor ; oboInOwl:creation_date "2010-08-25T03:22:08Z" ; oboInOwl:hasDbXref "FMA:62948" ; a owl:Class ; rdfs:label "epithelial cell of stomach" ; rdfs:subClassOf obo:CL_0002251, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000945 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000945 ] ) ] . obo:CL_0002180 obo:IAO_0000115 "A mucous cell in the epithelium of the stomach." ; terms:contributor ; oboInOwl:creation_date "2010-08-25T03:38:51Z" ; oboInOwl:hasDbXref "FMA:63464" ; a owl:Class ; rdfs:label "mucous cell of stomach" ; rdfs:subClassOf obo:CL_0002659, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001199 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002178 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001199 ] ) ] . obo:CL_0002183 obo:IAO_0000115 "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit." ; terms:contributor ; oboInOwl:creation_date "2010-08-25T03:57:08Z" ; oboInOwl:hasDbXref "FMA:62953" ; a owl:Class ; rdfs:label "stem cell of gastric gland" ; rdfs:subClassOf obo:CL_0000048, obo:CL_0000152, obo:CL_0002180, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000325 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000048 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000325 ] ) ] . obo:CL_0002195 obo:IAO_0000115 "A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes)." ; terms:contributor ; oboInOwl:creation_date "2010-08-30T02:00:42Z" ; oboInOwl:hasDbXref "FMA:86577" ; oboInOwl:hasExactSynonym "HpSC" ; a owl:Class ; rdfs:label "hepatic stem cell" ; rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" ; rdfs:subClassOf obo:CL_0000048, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002107 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000048 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002107 ] ) ] . obo:CL_0002202 obo:IAO_0000115 "An epithelial cell of the tracheobronchial tree." ; terms:contributor ; oboInOwl:creation_date "2010-09-02T02:09:14Z" ; oboInOwl:hasDbXref "FMA:66816" ; a owl:Class ; rdfs:label "epithelial cell of tracheobronchial tree" ; rdfs:subClassOf obo:CL_0002632, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007196 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007196 ] ) ] . obo:CL_0002209 obo:IAO_0000115 "An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells." ; terms:contributor ; oboInOwl:creation_date "2010-09-02T02:53:59Z" ; oboInOwl:hasDbXref "FMA:69060" ; oboInOwl:hasExactSynonym "undifferentiated columnar cell of tracheobronchial tree" ; a owl:Class ; rdfs:label "intermediate epitheliocyte" ; rdfs:subClassOf obo:CL_0002202 . obo:CL_0002222 obo:IAO_0000115 "A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye." ; terms:contributor ; oboInOwl:creation_date "2010-09-07T10:38:03Z" ; oboInOwl:hasDbXref "FMA:70950" ; a owl:Class ; rdfs:label "vertebrate lens cell" ; rdfs:subClassOf obo:CL_0000066, obo:CL_0000306, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000965 ] . obo:CL_0002224 obo:IAO_0000115 "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-09-07T10:45:47Z" ; oboInOwl:hasDbXref "FMA:67559" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "lens epithelial cell" ; rdfs:subClassOf obo:CL_0000075, obo:CL_0002222, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001803 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000075 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001803 ] ) ] . obo:CL_0002240 obo:IAO_0000115 "A fibroblast in the bone marrow." ; terms:contributor ; oboInOwl:creation_date "2010-09-07T02:25:18Z" ; oboInOwl:hasDbXref "FMA:84377" ; a owl:Class ; rdfs:label "marrow fibroblast" ; rdfs:subClassOf obo:CL_0000057, obo:CL_0002092 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002371 ] ) ] . obo:CL_0002241 obo:IAO_0000115 "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis." ; terms:contributor ; oboInOwl:creation_date "2010-09-07T02:29:38Z" ; oboInOwl:hasDbXref "FMA:84467" ; oboInOwl:hasExactSynonym "pulmonary myofibroblast", "pulmonary septal cell" ; a owl:Class ; rdfs:label "pulmonary interstitial fibroblast" ; rdfs:subClassOf obo:CL_0000057, obo:CL_4030031, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001004 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001004 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005169 ] ) ] . obo:CL_0002242 obo:IAO_0000115 "A cell containing at least one nucleus." ; terms:contributor ; oboInOwl:creation_date "2010-09-07T03:32:33Z" ; oboInOwl:hasDbXref "FMA:67513" ; a owl:Class ; rdfs:label "nucleate cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002505 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002505 ] ) ] . obo:CL_0002243 obo:IAO_0000115 "A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells." ; terms:contributor ; oboInOwl:creation_date "2010-09-08T08:53:42Z" ; oboInOwl:hasDbXref "FMA:70611" ; oboInOwl:hasExactSynonym "smooth muscle fiber of sphincter of pupil" ; oboInOwl:hasRelatedSynonym "smooth muscle fibre of sphincter of pupil" ; a owl:Class ; rdfs:label "smooth muscle cell of sphincter of pupil" ; rdfs:subClassOf obo:CL_0000358, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001607 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001607 ] ) ] . obo:CL_0002246 obo:IAO_0000115 "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells)." ; terms:contributor ; oboInOwl:creation_date "2010-09-07T03:57:09Z" ; oboInOwl:hasDbXref "BTO:0002669", "FMA:86711", "MESH:D000072916" ; oboInOwl:hasExactSynonym "PBSC" ; a owl:Class ; rdfs:label "peripheral blood stem cell" ; rdfs:subClassOf obo:CL_0000037, obo:CL_0000080, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000178 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000037 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000178 ] ) ] . obo:CL_0002251 obo:IAO_0000115 "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus." ; terms:contributor ; oboInOwl:creation_date "2010-09-08T09:26:53Z" ; a owl:Class ; rdfs:label "epithelial cell of alimentary canal" ; rdfs:subClassOf obo:CL_0002076, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001555 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001555 ] ) ] . obo:CL_0002252 obo:IAO_0000115 "An epithelial cell of the esophagus." ; terms:contributor ; oboInOwl:creation_date "2010-09-08T09:28:20Z" ; oboInOwl:hasDbXref "FMA:63071" ; a owl:Class ; rdfs:label "epithelial cell of esophagus" ; rdfs:subClassOf obo:CL_0002251, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001043 ] ) ] . obo:CL_0002253 obo:IAO_0000115 "An epithelial cell of the large intestine." ; terms:contributor ; oboInOwl:creation_date "2010-09-08T09:28:22Z" ; oboInOwl:hasDbXref "BTO:0004297", "FMA:256157" ; oboInOwl:hasRelatedSynonym "epithelial cell of colon" ; a owl:Class ; rdfs:label "epithelial cell of large intestine" ; rdfs:subClassOf obo:CL_0002563, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002563 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000059 ] ) ] . obo:CL_0002254 obo:IAO_0000115 "An epithelial cell of the small intestine." ; terms:contributor ; oboInOwl:creation_date "2010-09-08T09:41:46Z" ; oboInOwl:hasDbXref "FMA:256159" ; a owl:Class ; rdfs:label "epithelial cell of small intestine" ; rdfs:subClassOf obo:CL_0002563, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002108 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002563 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002108 ] ) ] . obo:CL_0002255 obo:IAO_0000115 "A stromal cell of the endometrium that is fibroblastic in appearance. During decidualization this cell may differentiate into a decidual stromal cell." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-09-08T09:50:04Z" ; oboInOwl:hasDbXref "CALOHA:TS-1266", "FMA:86490" ; oboInOwl:hasExactSynonym "endometrial stromal cell", "endometrial stromal fibroblast" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "stromal cell of endometrium" ; rdfs:subClassOf obo:CL_0000499, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002337 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002388 ; owl:someValuesFrom obo:CL_2000002 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000499 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001295 ] ) ] . obo:CL_0002262 obo:IAO_0000115 "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-09-14T10:57:26Z" ; oboInOwl:hasDbXref "FMA:63134" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "endothelial cell of sinusoid" ; rdfs:subClassOf obo:CL_0000115, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003909 ] ) ] . obo:CL_0002264 obo:IAO_0000115 "A type of enteroendocrine cell found in the stomach that secretes glucagon." ; terms:contributor ; oboInOwl:creation_date "2010-09-10T10:54:42Z" ; oboInOwl:hasDbXref "FMA:83411" ; a owl:Class ; rdfs:label "type A cell of stomach" ; rdfs:subClassOf obo:CL_0002067, obo:CL_0002659 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002067 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000945 ] ) ] . obo:CL_0002265 obo:IAO_0000115 "A D cell located in the colon." ; terms:contributor ; oboInOwl:creation_date "2010-09-10T11:37:35Z" ; oboInOwl:hasDbXref "FMA:268744" ; oboInOwl:hasExactSynonym "colon D-cell", "colonic delta cell", "delta cell of colon" ; a owl:Class ; rdfs:label "type D cell of colon" ; rdfs:subClassOf obo:CL_0000502, obo:CL_0009042 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001155 ] ) ] . obo:CL_0002266 obo:IAO_0000115 "A type D cell of the small intestine." ; terms:contributor ; oboInOwl:creation_date "2010-09-10T01:34:22Z" ; oboInOwl:hasDbXref "FMA:268736" ; oboInOwl:hasExactSynonym "delta cell of small intestine", "small intestine D-cell", "small intestine delta cell" ; a owl:Class ; rdfs:label "type D cell of small intestine" ; rdfs:subClassOf obo:CL_0000502, obo:CL_0009006 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002108 ] ) ] . obo:CL_0002267 obo:IAO_0000115 "A type D cell found in the stomach." ; terms:contributor ; oboInOwl:creation_date "2010-09-10T01:36:03Z" ; oboInOwl:hasDbXref "FMA:83410" ; oboInOwl:hasExactSynonym "delta cell of stomach", "stomach D-cell", "stomach delta cell" ; a owl:Class ; rdfs:label "type D cell of stomach" ; rdfs:subClassOf obo:CL_0000502, obo:CL_0002659 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000945 ] ) ] . obo:CL_0002275 obo:IAO_0000115 "A PP cell located in the islets of the pancreas." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-09-10T03:30:31Z" ; oboInOwl:hasDbXref "BTO:0000805", "FMA:70588", "MESH:D050418" ; oboInOwl:hasExactSynonym "PP cell of pancreatic islet", "PP-cell of pancreatic islet", "pancreatic polypeptide-secreting cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell." ; rdfs:label "pancreatic PP cell" ; rdfs:subClassOf obo:CL_0000696, obo:CL_0008024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000006 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000696 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000006 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001264 ] ) ] . obo:CL_0002308 obo:IAO_0000115 "An epithelial cell of a skin gland." ; terms:contributor ; oboInOwl:creation_date "2010-09-14T12:00:07Z" ; oboInOwl:hasDbXref "FMA:70657" ; oboInOwl:hasExactSynonym "epithelial cell of gland of skin" ; a owl:Class ; rdfs:label "epithelial cell of skin gland" ; rdfs:subClassOf obo:CL_0002159, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002419 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002419 ] ) ] . obo:CL_0002319 obo:IAO_0000115 "A cell that is part of the nervous system." ; terms:contributor ; oboInOwl:creation_date "2010-09-15T01:34:57Z" ; oboInOwl:hasDbXref "CALOHA:TS-2040", "FMA:70333" ; a owl:Class ; rdfs:label "neural cell" ; rdfs:subClassOf obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001016 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000548 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001016 ] ) ] . obo:CL_0002320 obo:IAO_0000115 "A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone." ; terms:contributor ; oboInOwl:creation_date "2010-09-15T03:01:54Z" ; oboInOwl:hasDbXref "CALOHA:TS-2096", "FMA:63875", "MESH:D003239" ; a owl:Class ; rdfs:label "connective tissue cell" ; rdfs:subClassOf obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002384 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002371 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002384 ] ) ] . obo:CL_0002321 obo:IAO_0000115 "A cell of the embryo." ; terms:contributor ; oboInOwl:creation_date "2010-09-15T03:39:21Z" ; oboInOwl:hasDbXref "CALOHA:TS-0263", "FMA:82840", "FMA:82841", "WBbt:0007028" ; a owl:Class ; rdfs:label "embryonic cell (metazoa)" ; rdfs:subClassOf obo:CL_0000548 . obo:CL_0002328 obo:IAO_0000115 "An epithelial cell of the bronchus." ; terms:contributor ; oboInOwl:creation_date "2010-09-20T02:00:00Z" ; oboInOwl:hasDbXref "BTO:0002922" ; a owl:Class ; rdfs:label "bronchial epithelial cell" ; rdfs:subClassOf obo:CL_0002202, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002185 ] ) ] . obo:CL_0002332 obo:IAO_0000115 "A ciliated cell of the bronchus." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-09-20T02:21:12Z" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "ciliated cell of the bronchus" ; rdfs:subClassOf obo:CL_0002145, obo:CL_0002328 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000064 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002185 ] ) ] . obo:CL_0002333 obo:IAO_0000115 "A fat cell derived from a neural crest cell." ; terms:contributor ; oboInOwl:creation_date "2010-09-20T02:25:25Z" ; a owl:Class ; rdfs:label "neural crest derived fat cell" ; rdfs:subClassOf obo:CL_0000136, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000136 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000333 ] ) ] . obo:CL_0002350 obo:IAO_0000115 "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-09-21T04:33:05Z" ; oboInOwl:hasDbXref "FMA:75621" ; oboInOwl:hasExactSynonym "endocardial endothelial cell", "endothelial cell of endocardium" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "endocardial cell" ; rdfs:subClassOf obo:CL_0010008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002165 ] ) ] . obo:CL_0002351 obo:IAO_0000115 "A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1." ; terms:contributor ; oboInOwl:creation_date "2010-09-21T04:41:06Z" ; oboInOwl:hasExactSynonym "pancreatic endocrine progenitor", "pancreatic islet progenitor cell" ; a owl:Class ; rdfs:label "progenitor cell of endocrine pancreas" ; rdfs:subClassOf obo:CL_0000548, obo:CL_0011026 . obo:CL_0002352 obo:IAO_0000115 "A hematopoietic stem cell that exists during embryogenesis." ; terms:contributor ; oboInOwl:creation_date "2010-09-22T09:05:13Z" ; a owl:Class ; rdfs:label "gestational hematopoietic stem cell" ; rdfs:subClassOf obo:CL_0000037, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000922 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000037 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000922 ] ) ] . obo:CL_0002359 obo:IAO_0000115 "A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells." ; terms:contributor ; oboInOwl:creation_date "2010-09-22T10:30:02Z" ; a owl:Class ; rdfs:label "placental hematopoietic stem cell" ; rdfs:subClassOf obo:CL_0002352, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000037 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001987 ] ) ] . obo:CL_0002363 obo:IAO_0000115 "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2010-09-22T01:57:40Z" ; oboInOwl:hasExactSynonym "corneal fibroblast", "corneal keratocyte" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "keratocyte" ; rdfs:subClassOf obo:CL_0000005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001777 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001777 ] ) ] . obo:CL_0002368 obo:IAO_0000115 "An endo-epithelial cell of the respiratory tract." ; terms:contributor ; oboInOwl:creation_date "2010-09-23T04:38:49Z" ; oboInOwl:hasDbXref "BTO:0004533" ; oboInOwl:hasExactSynonym "airway epithelial cell" ; a owl:Class ; rdfs:label "respiratory epithelial cell" ; rdfs:subClassOf obo:CL_0002076, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000065 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002076 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000065 ] ) ] . obo:CL_0002371 obo:IAO_0000115 "A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell)." ; terms:contributor ; oboInOwl:creation_date "2010-09-24T09:44:42Z" ; oboInOwl:hasDbXref "BTO:0001268", "FMA:72300", "WBbt:0008378" ; oboInOwl:inSubset ubprop:_upper_level ; a owl:Class ; rdfs:label "somatic cell" ; rdfs:subClassOf obo:CL_0000548 . obo:CL_0002372 obo:IAO_0000115 "A transversely striated, synctial muscle cell, formed by the fusion of myoblasts." ; terms:contributor ; oboInOwl:creation_date "2010-09-24T01:13:01Z" ; oboInOwl:hasDbXref "FBbt:00005812" ; oboInOwl:hasExactSynonym "myotubule", "single cell sarcomere" ; a owl:Class ; rdfs:label "myotube" ; rdfs:subClassOf obo:CL_0000228, obo:CL_0000737, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002478 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000187 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001908 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002478 ] ) ] . obo:CL_0002421 obo:IAO_0000115 "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles." ; terms:contributor ; oboInOwl:creation_date "2010-10-15T09:24:05Z" ; a owl:Class ; rdfs:label "nucleated reticulocyte" ; rdfs:subClassOf obo:CL_0000558, obo:CL_0002242 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000558 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002505 ] ) ] . obo:CL_0002422 obo:IAO_0000115 "A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes." ; terms:contributor ; oboInOwl:creation_date "2010-10-15T09:24:08Z" ; oboInOwl:hasDbXref "CALOHA:TS-0864", "FMA:66785" ; a owl:Class ; rdfs:label "enucleated reticulocyte" ; rdfs:subClassOf obo:CL_0000225, obo:CL_0000558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005840 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000558 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005840 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001405 ] ) ] . obo:CL_0002494 obo:IAO_0000115 "A cell located in the heart, including both muscle and non muscle cells." ; terms:contributor ; oboInOwl:creation_date "2010-12-07T09:37:22Z" ; oboInOwl:hasDbXref "BTO:0001539", "CALOHA:TS-0115", "FMA:83808", "FMA:84791" ; oboInOwl:hasExactSynonym "heart cell" ; a owl:Class ; rdfs:comment "From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart." ; rdfs:label "cardiocyte" ; rdfs:subClassOf obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007100 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002371 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007100 ] ) ] . obo:CL_0002503 obo:IAO_0000115 "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc" ; terms:contributor ; oboInOwl:creation_date "2010-12-07T04:03:56Z" ; oboInOwl:hasDbXref "BTO:0002441", "FMA:84639" ; a owl:Class ; rdfs:label "adventitial cell" ; rdfs:subClassOf obo:CL_0000630, obo:CL_0002320, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005742 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002320 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005742 ] ) ] . obo:CL_0002504 obo:IAO_0000115 "A smooth muscle cell of the intestine." ; terms:contributor ; oboInOwl:creation_date "2011-01-17T03:39:38Z" ; oboInOwl:hasExactSynonym "intestinal smooth muscle cell" ; a owl:Class ; rdfs:label "enteric smooth muscle cell" ; rdfs:subClassOf obo:CL_0000192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000160 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000160 ] ) ] . obo:CL_0002518 obo:IAO_0000115 "An epithelial cell of the kidney." ; terms:contributor ; oboInOwl:creation_date "2011-02-08T10:46:34Z" ; oboInOwl:hasDbXref "KUPO:0001019" ; a owl:Class ; rdfs:label "kidney epithelial cell" ; rdfs:subClassOf obo:CL_0000066, obo:CL_1000497 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002113 ] ) ] . obo:CL_0002521 obo:IAO_0000115 "A fat cell that is part of subcutaneous adipose tissue." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2011-02-21T02:51:22Z" ; oboInOwl:hasExactSynonym "subcutaneous adipocyte" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "subcutaneous fat cell" ; rdfs:subClassOf obo:CL_0000136, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002190 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000136 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002190 ] ) ] . obo:CL_0002538 obo:IAO_0000115 "An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes." ; terms:contributor ; oboInOwl:creation_date "2011-02-28T01:20:20Z" ; oboInOwl:hasExactSynonym "small bile duct cholangiocyte" ; a owl:Class ; rdfs:label "intrahepatic cholangiocyte" ; rdfs:subClassOf obo:CL_1000488, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004823 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000488 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004823 ] ) ] . obo:CL_0002539 obo:IAO_0000115 "A smooth muscle cell of the aorta." ; terms:contributor ; oboInOwl:creation_date "2011-02-28T01:42:12Z" ; oboInOwl:hasDbXref "BTO:0004577" ; a owl:Class ; rdfs:label "aortic smooth muscle cell" ; rdfs:subClassOf obo:CL_0019018, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004178 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000359 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004178 ] ) ] . obo:CL_0002540 obo:IAO_0000115 "A mesenchymal stem cell that is part of the bone marrow." ; terms:contributor ; oboInOwl:creation_date "2011-02-28T01:47:47Z" ; a owl:Class ; rdfs:label "mesenchymal stem cell of the bone marrow" ; rdfs:subClassOf obo:CL_0000134, obo:CL_0002092 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000134 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002371 ] ) ] . obo:CL_0002541 obo:IAO_0000115 "A mesenchymal stem cell of the chorionic membrane." ; terms:contributor ; oboInOwl:creation_date "2011-02-28T03:04:35Z" ; a owl:Class ; rdfs:label "chorionic membrane mesenchymal stem cell" ; rdfs:subClassOf obo:CL_0000134, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003124 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000134 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003124 ] ) ] . obo:CL_0002543 obo:IAO_0000115 "An endothelial cell that is part of the vein." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2011-02-28T03:48:11Z" ; oboInOwl:hasDbXref "FMA:62104", "KUPO:0001099" ; oboInOwl:hasExactSynonym "endothelial cell of vein", "venous endothelial cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "vein endothelial cell" ; rdfs:subClassOf obo:CL_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001638 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000071 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001638 ] ) ] . obo:CL_0002546 obo:IAO_0000115 "An endothelial progenitor cell that participates in angiogenesis during development." ; terms:contributor ; oboInOwl:creation_date "2011-02-28T04:20:39Z" ; a owl:Class ; rdfs:comment "See CL:0002619." ; rdfs:label "embryonic blood vessel endothelial progenitor cell" ; rdfs:subClassOf obo:CL_0000222, obo:CL_0002371 . obo:CL_0002547 obo:IAO_0000115 "A fibroblast of the aortic adventitia." ; terms:contributor ; oboInOwl:creation_date "2011-02-28T04:43:41Z" ; a owl:Class ; rdfs:label "fibroblast of the aortic adventitia" ; rdfs:subClassOf obo:CL_1000306, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004664 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000306 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004664 ] ) ] . obo:CL_0002548 obo:IAO_0000115 "A fibroblast that is part of the heart." ; terms:contributor ; oboInOwl:creation_date "2011-02-28T04:57:44Z" ; oboInOwl:hasExactSynonym "cardiac fibroblast" ; a owl:Class ; rdfs:label "fibroblast of cardiac tissue" ; rdfs:subClassOf obo:CL_0000057, obo:CL_0002494, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000948 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000948 ] ) ] . obo:CL_0002551 terms:contributor ; oboInOwl:creation_date "2011-02-28T05:05:33Z" ; a owl:Class ; rdfs:label "fibroblast of dermis" ; rdfs:subClassOf obo:CL_0002620, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002067 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002620 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002067 ] ) ] . obo:CL_0002553 obo:IAO_0000115 "A fibroblast that is part of lung." ; terms:contributor ; oboInOwl:creation_date "2011-02-28T05:11:03Z" ; oboInOwl:hasDbXref "BTO:0000764", "CALOHA:TS-0575" ; a owl:Class ; rdfs:label "fibroblast of lung" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_0002557 obo:IAO_0000115 "A fibroblast of pulmonary artery." ; terms:contributor ; oboInOwl:creation_date "2011-02-28T05:22:27Z" ; a owl:Class ; rdfs:label "fibroblast of pulmonary artery" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002012 ] ) ] . obo:CL_0002563 obo:IAO_0000115 "An epithelial cell of the intestine." ; terms:contributor ; oboInOwl:creation_date "2011-03-01T05:18:31Z" ; a owl:Class ; rdfs:label "intestinal epithelial cell" ; rdfs:subClassOf obo:CL_0002251, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001277 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000160 ] ) ] . obo:CL_0002569 obo:IAO_0000115 "A mesenchymal stem cell of the umbilical cord." ; terms:contributor ; oboInOwl:creation_date "2011-03-01T09:55:12Z" ; a owl:Class ; rdfs:label "mesenchymal stem cell of umbilical cord" ; rdfs:subClassOf obo:CL_0000134, obo:CL_0000349, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003422 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000134 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003422 ] ) ] . obo:CL_0002570 obo:IAO_0000115 "A mesenchymal stem cell of adipose tissue." ; terms:contributor ; oboInOwl:creation_date "2011-03-01T09:57:17Z" ; oboInOwl:hasExactSynonym "mesenchymal stem cell of adipose" ; a owl:Class ; rdfs:label "mesenchymal stem cell of adipose tissue" ; rdfs:subClassOf obo:CL_0000134, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000134 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001013 ] ) ] . obo:CL_0002571 obo:IAO_0000115 "A mesenchymal stem cell of liver." ; terms:contributor ; oboInOwl:creation_date "2011-03-01T09:58:51Z" ; a owl:Class ; rdfs:label "hepatic mesenchymal stem cell" ; rdfs:subClassOf obo:CL_0000134, obo:CL_0002195 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000134 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002107 ] ) ] . obo:CL_0002574 obo:IAO_0000115 "A stromal cell of the pancreas." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2011-03-02T02:40:41Z" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "stromal cell of pancreas" ; rdfs:subClassOf obo:CL_0000499, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000499 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001264 ] ) ] . obo:CL_0002577 obo:IAO_0000115 "An epithelial cell of the placenta." ; terms:contributor ; oboInOwl:creation_date "2011-03-02T03:21:30Z" ; a owl:Class ; rdfs:label "placental epithelial cell" ; rdfs:subClassOf obo:CL_0000066, obo:CL_0000349, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001987 ] ) ] . obo:CL_0002584 obo:IAO_0000115 "An epithelial cell of the kidney cortex." ; oboInOwl:hasDbXref "KUPO:0001016" ; a owl:Class ; rdfs:label "renal cortical epithelial cell" ; rdfs:subClassOf obo:CL_0002518, obo:CL_0002681 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002518 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001225 ] ) ] . obo:CL_0002585 obo:IAO_0000115 "A blood vessel endothelial cell that is part of the retina." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2011-03-06T03:28:27Z" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "retinal blood vessel endothelial cell" ; rdfs:subClassOf obo:CL_0000071, obo:CL_0009004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000966 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000071 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000966 ] ) ] . obo:CL_0002589 obo:IAO_0000115 "A smooth muscle cell of the bachiocephalic vasculature." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:00:58Z" ; a owl:Class ; rdfs:label "smooth muscle cell of the brachiocephalic vasculature" ; rdfs:subClassOf obo:CL_0019018, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001529 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000359 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001529 ] ) ] . obo:CL_0002590 obo:IAO_0000115 "A vascular associated smooth muscle cell of the brain vasculature." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:01:20Z" ; a owl:Class ; rdfs:label "smooth muscle cell of the brain vasculature" ; rdfs:subClassOf obo:CL_0000359, obo:CL_0002319, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000359 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000955 ] ) ] . obo:CL_0002591 obo:IAO_0000115 "A smooth muscle of the pulmonary artery." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:01:28Z" ; oboInOwl:hasDbXref "BTO:0003336" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "smooth muscle cell of the pulmonary artery" ; rdfs:subClassOf obo:CL_0019018, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000359 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002012 ] ) ] . obo:CL_0002594 obo:IAO_0000115 "A smooth muscle cell of the umbilical artery." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:01:48Z" ; a owl:Class ; rdfs:label "smooth muscle cell of the umbilical artery" ; rdfs:subClassOf obo:CL_0019018, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000359 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001310 ] ) ] . obo:CL_0002595 obo:IAO_0000115 "A smooth muscle cell of the subclavian artery." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:01:52Z" ; a owl:Class ; rdfs:label "smooth muscle cell of the subclavian artery" ; rdfs:subClassOf obo:CL_0019018, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001533 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000359 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001533 ] ) ] . obo:CL_0002596 obo:IAO_0000115 "Smooth muscle cell of the carotid artery." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:01:56Z" ; a owl:Class ; rdfs:label "smooth muscle cell of the carotid artery" ; rdfs:subClassOf obo:CL_0019018, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005396 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000359 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005396 ] ) ] . obo:CL_0002597 obo:IAO_0000115 "A smooth muscle cell of the bladder." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:43:24Z" ; oboInOwl:hasDbXref "KUPO:0001122" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "smooth muscle cell of bladder" ; rdfs:subClassOf obo:CL_0000192, obo:CL_1001319 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001255 ] ) ] . obo:CL_0002598 obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:46:39Z" ; oboInOwl:hasDbXref "BTO:0004402" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "bronchial smooth muscle cell" ; rdfs:subClassOf obo:CL_0019019, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002185 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002185 ] ) ] . obo:CL_0002599 obo:IAO_0000115 "A smooth muscle cell of the esophagus." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:48:17Z" ; a owl:Class ; rdfs:label "smooth muscle cell of the esophagus" ; rdfs:subClassOf obo:CL_0000192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001043 ] ) ] . obo:CL_0002600 obo:IAO_0000115 "A smooth muscle cell of the trachea." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:50:28Z" ; a owl:Class ; rdfs:label "smooth muscle cell of trachea" ; rdfs:subClassOf obo:CL_0019019, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003126 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003126 ] ) ] . obo:CL_0002601 obo:IAO_0000115 "A smooth muscle cell of the uterus." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T05:53:28Z" ; a owl:Class ; rdfs:label "uterine smooth muscle cell" ; rdfs:subClassOf obo:CL_0000192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000995 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000995 ] ) ] . obo:CL_0002610 obo:IAO_0000115 "A neuron of the raphe nuclei." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T07:42:06Z" ; a owl:Class ; rdfs:label "raphe nuclei neuron" ; rdfs:subClassOf obo:CL_0000117, obo:CL_2000029, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0004684 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000117 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0004684 ] ) ] . obo:CL_0002612 obo:IAO_0000115 "A neuron of the ventral spinal cord." ; terms:contributor ; oboInOwl:creation_date "2011-03-06T07:46:03Z" ; a owl:Class ; rdfs:label "neuron of the ventral spinal cord" ; rdfs:subClassOf obo:CL_0000117, obo:CL_2000029, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002257 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000117 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002257 ] ) ] . obo:CL_0002620 obo:IAO_0000115 "A fibroblast of skin." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2011-03-14T12:31:49Z" ; oboInOwl:hasDbXref "BTO:0001255", "CALOHA:TS-0935" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "skin fibroblast" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002097 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002097 ] ) ] . obo:CL_0002625 obo:IAO_0000115 "A cell of the seminiferous tubule epithelium." ; terms:contributor ; oboInOwl:creation_date "2011-03-15T11:59:23Z" ; a owl:Class ; rdfs:label "seminiferous tubule epithelial cell" ; rdfs:subClassOf obo:CL_0000068, obo:CL_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004813 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001343 ] ) ] . obo:CL_0002632 terms:contributor ; oboInOwl:creation_date "2011-06-21T12:29:31Z" ; a owl:Class ; rdfs:label "epithelial cell of lower respiratory tract" ; rdfs:subClassOf obo:CL_0002368, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001558 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002368 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001558 ] ) ] . obo:CL_0002656 obo:IAO_0000115 "A glandular epithelial cell of the endometrium." ; terms:contributor ; oboInOwl:creation_date "2011-07-08T03:54:08Z" ; oboInOwl:hasDbXref "FMA:86489" ; a owl:Class ; rdfs:label "glandular cell of endometrium" ; rdfs:subClassOf obo:CL_1001591, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001295 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001295 ] ) ] . obo:CL_0002657 obo:IAO_0000115 "A glandular epithelial cell of the esophagus." ; terms:contributor ; oboInOwl:creation_date "2011-07-08T03:55:57Z" ; oboInOwl:hasDbXref "FMA:86548" ; a owl:Class ; rdfs:label "glandular cell of esophagus" ; rdfs:subClassOf obo:CL_0000150, obo:CL_0002252 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001043 ] ) ] . obo:CL_0002658 obo:IAO_0000115 "A glandular epithelial cell of the large intestine." ; terms:contributor ; oboInOwl:creation_date "2011-07-08T04:03:01Z" ; oboInOwl:hasDbXref "FMA:87194" ; a owl:Class ; rdfs:label "glandular cell of the large intestine" ; rdfs:subClassOf obo:CL_0000150, obo:CL_0002253 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000059 ] ) ] . obo:CL_0002659 obo:IAO_0000115 "A glandular epithelial cell that is part of the stomach." ; terms:contributor ; oboInOwl:creation_date "2011-07-11T01:20:35Z" ; oboInOwl:hasDbXref "CALOHA:TS-1284", "FMA:86554" ; a owl:Class ; rdfs:label "glandular cell of stomach" ; rdfs:subClassOf obo:CL_0000150, obo:CL_0002178 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000945 ] ) ] . obo:CL_0002663 obo:IAO_0000115 "A myocardial endocrine cell that is part of the atrium." ; terms:contributor ; oboInOwl:creation_date "2011-07-11T02:45:39Z" ; oboInOwl:hasDbXref "FMA:83389" ; a owl:Class ; rdfs:label "myocardial endocrine cell of atrium" ; rdfs:subClassOf obo:CL_0002074, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002074 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002081 ] ) ] . obo:CL_0002664 obo:IAO_0000115 "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart." ; terms:contributor ; oboInOwl:creation_date "2011-07-11T03:15:38Z" ; oboInOwl:hasExactSynonym "CPC", "cardiovascular progenitor cell" ; a owl:Class ; rdfs:comment "Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell." ; rdfs:label "cardioblast" ; rdfs:subClassOf obo:CL_0000048 . obo:CL_0002672 obo:IAO_0000115 "A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells." ; terms:contributor ; oboInOwl:creation_date "2011-08-16T02:38:01Z" ; a owl:Class ; rdfs:label "retinal progenitor cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000048, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000133 ] . obo:CL_0002676 obo:IAO_0000115 "A neuroblast derived from a neural crest cell." ; terms:contributor ; oboInOwl:creation_date "2011-08-22T09:24:15Z" ; a owl:Class ; rdfs:label "neural crest derived neuroblast" ; rdfs:subClassOf obo:CL_0000031, obo:CL_0011026, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000333 ] . obo:CL_0002680 obo:IAO_0000115 "A PP cell found in intestine." ; terms:contributor ; oboInOwl:creation_date "2011-09-27T11:59:01Z" ; a owl:Class ; rdfs:label "PP cell of intestine" ; rdfs:subClassOf obo:CL_0000696, obo:CL_1001516 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000696 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000160 ] ) ] . obo:CL_0002681 terms:contributor ; oboInOwl:creation_date "2011-10-25T03:49:41Z" ; a owl:Class ; rdfs:label "kidney cortical cell" ; rdfs:subClassOf obo:CL_1000497, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001225 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000497 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001225 ] ) ] . obo:CL_0005000 obo:IAO_0000115 "A CNS interneuron located in the spinal cord." ; a owl:Class ; rdfs:comment "Is_a interneuron, part_of UBERON:0002240." ; rdfs:label "spinal cord interneuron" ; rdfs:subClassOf obo:CL_0000402, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002240 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000099 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002240 ] ) ] . obo:CL_0005009 obo:IAO_0000115 "A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system." ; a owl:Class ; rdfs:label "renal principal cell" ; rdfs:subClassOf obo:CL_0000075, obo:CL_0002518 . obo:CL_0005012 obo:IAO_0000115 "A ciliated epithelial cell with many cilia." ; oboInOwl:hasBroadSynonym "MCC"@en, "multi-ciliated cell"@en, "multiciliated cell"@en ; oboInOwl:hasExactSynonym "multiciliated epithelial cell"@en ; a owl:Class ; rdfs:label "multi-ciliated epithelial cell" ; rdfs:subClassOf obo:CL_0000067 . obo:CL_0005024 obo:IAO_0000115 "A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic." ; oboInOwl:hasExactSynonym "somatic motor neuron" ; a owl:Class ; rdfs:label "somatomotor neuron"@en ; rdfs:subClassOf obo:CL_0000100, obo:CL_0000108, [ a owl:Restriction ; owl:onProperty obo:RO_0002120 ; owl:someValuesFrom obo:CL_0008002 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000100 [ a owl:Restriction ; owl:onProperty obo:RO_0002120 ; owl:someValuesFrom obo:CL_0008002 ] ) ] . obo:CL_0005026 obo:IAO_0000115 "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation." ; a owl:Class ; rdfs:label "hepatoblast"@en ; rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/800" ; rdfs:subClassOf obo:CL_0000048 . obo:CL_0007001 obo:IAO_0000115 "Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized)." ; terms:contributor ; oboInOwl:creation_date "2012-06-15T02:51:27Z" ; oboInOwl:hasExactSynonym "scleroblast" ; a owl:Class ; rdfs:comment "Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts)" ; rdfs:label "skeletogenic cell" ; rdfs:subClassOf obo:CL_0000003 . obo:CL_0007004 obo:IAO_0000115 "Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells." ; terms:contributor ; oboInOwl:creation_date "2012-06-27T08:27:35Z" ; a owl:Class ; rdfs:label "premigratory neural crest cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0011012, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002342 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000133 ] . obo:CL_0007009 obo:IAO_0000115 "Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells." ; terms:contributor ; oboInOwl:creation_date "2012-06-27T10:44:01Z" ; a owl:Class ; rdfs:label "prechondroblast" ; rdfs:subClassOf obo:CL_0000055, obo:CL_0000548 . obo:CL_0008000 obo:IAO_0000115 "Any muscle cell in which the fibers are not organised into sarcomeres." ; a owl:Class ; rdfs:label "non-striated muscle cell" ; rdfs:subClassOf obo:CL_0000187 . obo:CL_0008001 obo:IAO_0000115 "Any hematopoietic cell that is a precursor of some other hematopoietic cell type." ; a owl:Class ; rdfs:label "hematopoietic precursor cell" ; rdfs:subClassOf obo:CL_0000988 . obo:CL_0008002 obo:IAO_0000115 "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ; oboInOwl:hasDbXref "MESH:D018485" ; a owl:Class ; rdfs:label "skeletal muscle fiber"@en ; rdfs:subClassOf obo:CL_0000188, obo:CL_0002372, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000515 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000187 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001134 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001908 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002478 ] ) ] . obo:CL_0008007 obo:IAO_0000115 "A muscle cell that is part of some visceral muscle." ; oboInOwl:hasDbXref "FBbt:00005070" ; a owl:Class ; rdfs:label "visceral muscle cell"@en ; rdfs:subClassOf obo:CL_0000187, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8600004 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000187 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8600004 ] ) ] . obo:CL_0008008 obo:IAO_0000115 "A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods." ; a owl:Class ; rdfs:label "striated visceral muscle cell"@en ; rdfs:subClassOf obo:CL_0000737, obo:CL_0008007 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0008007 [ a owl:Class ; owl:intersectionOf ([ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001410 ] ) ] ) ] . obo:CL_0008009 obo:IAO_0000115 "A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods." ; a owl:Class ; rdfs:label "transversely striated visceral muscle cell"@en ; rdfs:subClassOf obo:CL_0008008, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002478 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0008007 [ a owl:Class ; owl:intersectionOf ([ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002478 ] ) ] ) ] . obo:CL_0008017 obo:IAO_0000115 "A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers." ; oboInOwl:hasBroadSynonym "myogenic precursor cell" ; a owl:Class ; rdfs:comment "The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins." ; rdfs:label "adult skeletal muscle myoblast" ; rdfs:subClassOf obo:CL_0000188, obo:CL_0000515 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000056 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001134 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0008002 ] ) ] . obo:CL_0008019 obo:IAO_0000115 "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration." ; oboInOwl:hasExactSynonym "mesenchyme cell" ; a owl:Class ; rdfs:label "mesenchymal cell" ; rdfs:subClassOf obo:CL_0000219, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003104 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0016477 ] . obo:CL_0008022 obo:IAO_0000115 "A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves." ; a owl:Class ; rdfs:label "endocardial cushion cell" ; rdfs:subClassOf obo:CL_0000569, obo:CL_0002494, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000569 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002062 ] ) ] . obo:CL_0008024 obo:IAO_0000115 "An endocrine cell that is part of the pancreas." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "pancreatic endocrine cell" ; rdfs:subClassOf obo:CL_0000083, obo:CL_0000164 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000163 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001264 ] ) ] . obo:CL_0008025 obo:IAO_0000115 "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter." ; a owl:Class ; rdfs:label "noradrenergic neuron" ; rdfs:subClassOf obo:CL_0000459, obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0061533 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0061533 ] ) ] . obo:CL_0008028 terms:contributor ; oboInOwl:creation_date "2017-07-09T19:12:36Z"^^xsd:dateTime ; a owl:Class ; rdfs:label "visual system neuron" ; rdfs:subClassOf obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0007601 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0007601 ] ) ] . obo:CL_0008034 obo:IAO_0000115 "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2020-02-29T17:33:55Z"^^xsd:dateTime ; oboInOwl:inSubset cl:added_for_HCA, core:human_reference_atlas ; a owl:Class ; rdfs:label "mural cell"@en ; rdfs:subClassOf obo:CL_0002371 . obo:CL_0008035 terms:contributor ; oboInOwl:creation_date "2020-02-29T17:37:00Z"^^xsd:dateTime ; a owl:Class ; rdfs:label "microcirculation associated smooth muscle cell"@en ; rdfs:subClassOf obo:CL_0000359, obo:CL_0008034, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0010523 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000359 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0010523 ] ) ] . obo:CL_0009000 obo:IAO_0000115 "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord." ; oboInOwl:hasExactSynonym "spinal sensory neuron" ; a owl:Class ; rdfs:label "sensory neuron of spinal nerve" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_3000004, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0001780 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000101 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0001780 ] ) ] . obo:CL_0009001 obo:IAO_0000115 "Any cell in the compound eye, a light sensing organ composed of ommatidia." ; oboInOwl:hasDbXref "GOC:pr", "PMID:12021768" ; a owl:Class ; rdfs:label "compound eye retinal cell" ; rdfs:subClassOf obo:CL_0009004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:UBERON_0005388 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000018 ] ) ] ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:UBERON_0005388 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000018 ] ) ] ] ) ] . obo:CL_0009004 obo:IAO_0000115 "Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." ; oboInOwl:hasDbXref "PMID:10702418" ; a owl:Class ; rdfs:label "retinal cell" ; rdfs:subClassOf obo:CL_0002319, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005388 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002319 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005388 ] ) ] . obo:CL_0009006 obo:IAO_0000115 "An enteroendocrine cell that is located in the small intestine." ; terms:contributor ; oboInOwl:hasExactSynonym "small intestine enteroendocrine cell" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "enteroendocrine cell of small intestine" ; rdfs:subClassOf obo:CL_1001516, obo:CL_1001598 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000164 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002108 ] ) ] . obo:CL_0009018 obo:IAO_0000115 "A lymphocyte that resides in the lamina propria of the large intestine." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:hasExactSynonym "lamina propria lymphocyte of large intestine" ; oboInOwl:inSubset pato:location_grouping, core:human_reference_atlas ; a owl:Class ; rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you." ; rdfs:label "lymphocyte of large intestine lamina propria" ; rdfs:subClassOf obo:CL_0000542, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0011189 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000542 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0011189 ] ) ] . obo:CL_0009019 obo:IAO_0000115 "A kidney cortical cell that is part of the nephrogenic zone." ; terms:contributor ; oboInOwl:hasExactSynonym "cortical nephrogenic niche cell", "cortical nephrogenic zone cell" ; oboInOwl:inSubset cl:added_for_HCA ; a owl:Class ; rdfs:label "nephrogenic zone cell" ; rdfs:subClassOf obo:CL_0002681, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0009871 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002681 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0009871 ] ) ] . obo:CL_0009021 obo:IAO_0000115 "A stromal cell found in the lamina propria of the large intestine." ; terms:contributor ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "stromal cell of lamina propria of large intestine" ; rdfs:subClassOf obo:CL_0000499, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0011189 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000499 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0011189 ] ) ] . obo:CL_0009022 obo:IAO_0000115 "A stromal cell found in the lamina propria of the small intestine." ; terms:contributor ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "stromal cell of lamina propria of small intestine" ; rdfs:subClassOf obo:CL_0000499, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001238 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000499 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001238 ] ) ] . obo:CL_0009024 obo:IAO_0000115 "A mesothelial cell that is part of the small intestine." ; terms:contributor ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "mesothelial cell of small intestine" ; rdfs:subClassOf obo:CL_0000077, obo:CL_0002254 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002108 ] ) ] . obo:CL_0009025 obo:IAO_0000115 "A mesothelial cell that is part of the colon." ; terms:contributor ; oboInOwl:hasBroadSynonym "mesothelial cell of large intestine" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "mesothelial cell of colon" ; rdfs:subClassOf obo:CL_0000077, obo:CL_0011108 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001155 ] ) ] . obo:CL_0009040 obo:IAO_0000115 "A stromal cell found in the lamina propria of the colon." ; terms:contributor ; oboInOwl:hasExactSynonym "stromal cell of colon lamina propria" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "stromal cell of lamina propria of colon" ; rdfs:subClassOf obo:CL_0009021, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007177 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000499 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007177 ] ) ] . obo:CL_0009042 obo:IAO_0000115 "An enteroendocrine cell that is located in the colon." ; terms:contributor ; oboInOwl:hasExactSynonym "colon enteroendocrine cell" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "enteroendocrine cell of colon" ; rdfs:subClassOf obo:CL_1001516, obo:CL_1001588 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000164 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001155 ] ) ] . obo:CL_0009044 obo:IAO_0000115 "A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response." ; terms:contributor ; oboInOwl:hasBroadSynonym "gastrointestinal tract small intestine (lamina propria) leukocyte", "small intestine lamina propria leukocyte", "small intestine lamina propria leukocyte (LPL)" ; oboInOwl:hasExactSynonym "gastrointestinal tract (lamina propria) lymphocyte of small intestine", "lamina propria lymphocyte of small intestine", "small intestine lamina propria lymphocyte" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you." ; rdfs:label "lymphocyte of small intestine lamina propria" ; rdfs:subClassOf obo:CL_0000542, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001238 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000542 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001238 ] ) ] . obo:CL_0009051 obo:IAO_0000115 "A T cell that is located in the anorectum." ; terms:contributor ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you." ; rdfs:label "T cell of anorectum" ; rdfs:subClassOf obo:CL_0000084, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410050 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000084 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410050 ] ) ] . obo:CL_0009052 obo:IAO_0000115 "A smooth muscle cell that is located in the anorectum." ; terms:contributor ; oboInOwl:hasExactSynonym "anorectum smooth muscle cell" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "smooth muscle cell of anorectum" ; rdfs:subClassOf obo:CL_1000279, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410050 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410050 ] ) ] . obo:CL_0009053 obo:IAO_0000115 "A stromal cell found in the lamina propria of the anorectum." ; terms:contributor ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "stromal cell of anorectum lamina propria" ; rdfs:subClassOf obo:CL_0009021, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410050 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000499 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0011189 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410050 ] ) ] . obo:CL_0009063 obo:IAO_0000115 "An enteroendocrine cell that is located in the anorectum." ; terms:contributor ; oboInOwl:hasExactSynonym "anorectum enteroendocrine cell" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "enteroendocrine cell of anorectum" ; rdfs:subClassOf obo:CL_0002658, obo:CL_1001516, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410050 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000164 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410050 ] ) ] . obo:CL_0009084 obo:IAO_0000115 "An epithelial cell that is part of an endometrial gland." ; terms:contributor ; terms:date "2021-11-30T16:13:30Z"^^xsd:dateTime ; oboInOwl:hasDbXref "EFO:0010710" ; oboInOwl:hasExactSynonym "endometrial glandular epithelial cell" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "epithelial cell of endometrial gland" ; rdfs:subClassOf obo:CL_0000066, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002451 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002451 ] ) ] . obo:CL_0009092 obo:IAO_0000115 "An endothelial cell that is part of a placenta." ; terms:contributor ; terms:date "2021-12-13T13:53:01Z"^^xsd:dateTime ; oboInOwl:hasDbXref "EFO:0010708" ; oboInOwl:hasExactSynonym "placental endothelial cell" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "endothelial cell of placenta" ; rdfs:subClassOf obo:CL_0000115, obo:CL_0002577 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001987 ] ) ] . obo:CL_0009093 obo:IAO_0000115 "A smooth muscle cell that is part of a placenta." ; terms:contributor ; terms:date "2021-12-13T13:56:42Z"^^xsd:dateTime ; oboInOwl:hasDbXref "EFO:0010709" ; oboInOwl:hasExactSynonym "placental smooth muscle cell" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "smooth muscle cell of placenta" ; rdfs:subClassOf obo:CL_0000192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001987 ] ) ] . obo:CL_0009094 obo:IAO_0000115 "An endothelial cell that is part of a hepatic portal vein." ; terms:contributor ; terms:date "2021-12-13T14:01:05Z"^^xsd:dateTime ; oboInOwl:hasBroadSynonym "portal endothelial cell" ; oboInOwl:hasDbXref "EFO:0010704" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "endothelial cell of hepatic portal vein" ; rdfs:subClassOf obo:CL_0000115, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001639 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001639 ] ) ] . obo:CL_0009095 obo:IAO_0000115 "An endothelial cell that is part of a uterus." ; terms:contributor ; terms:date "2021-12-13T14:39:25Z"^^xsd:dateTime ; oboInOwl:hasDbXref "EFO:0010711" ; oboInOwl:hasExactSynonym "uterine endothelial cell" ; oboInOwl:inSubset pato:location_grouping ; a owl:Class ; rdfs:label "endothelial cell of uterus" ; rdfs:subClassOf obo:CL_0000115, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000995 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000995 ] ) ] . obo:CL_0009097 obo:IAO_0000115 "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development." ; terms:contributor ; terms:date "2022-02-21T15:39:10Z"^^xsd:dateTime ; a owl:Class ; rdfs:label "embryonic skeletal muscle fiber" ; rdfs:subClassOf obo:CL_0008002, [ a owl:Restriction ; owl:onProperty obo:RO_0002491 ; owl:someValuesFrom obo:UBERON_0000068 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0008002 [ a owl:Restriction ; owl:onProperty obo:RO_0002491 ; owl:someValuesFrom obo:UBERON_0000068 ] ) ] . obo:CL_0009100 obo:IAO_0000115 "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen." ; terms:contributor ; terms:date "2022-03-17T12:00:44Z"^^xsd:dateTime ; oboInOwl:hasBroadSynonym "portal fibroblast" ; a owl:Class ; rdfs:label "hepatic portal fibroblast" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001279 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001279 ] ) ] . obo:CL_0010001 obo:IAO_0000115 "A stromal cell that is part_of a bone marrow." ; terms:contributor ; oboInOwl:hasExactSynonym "bone marrow stromal cell" ; a owl:Class ; rdfs:label "stromal cell of bone marrow" ; rdfs:subClassOf obo:CL_0000499, obo:CL_0002092 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000499 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002371 ] ) ] . obo:CL_0010002 obo:IAO_0000115 "An epithelial cell that is part_of a umbilical artery." ; terms:contributor ; oboInOwl:hasExactSynonym "umbilical artery epithelial cell" ; a owl:Class ; rdfs:label "epithelial cell of umbilical artery" ; rdfs:subClassOf obo:CL_0000066, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001310 ] ) ] . obo:CL_0010004 obo:IAO_0000115 "A mononuclear cell that is part_of a bone marrow." ; terms:contributor ; oboInOwl:hasExactSynonym "bone marrow mononuclear cell" ; a owl:Class ; rdfs:label "mononuclear cell of bone marrow" ; rdfs:subClassOf obo:CL_0000842, obo:CL_1001610 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000842 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002371 ] ) ] . obo:CL_0010006 a owl:Class ; rdfs:label "cardiac blood vessel endothelial cell" ; rdfs:subClassOf obo:CL_0000071, obo:CL_0010008 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000071 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000948 ] ) ] . obo:CL_0010007 a owl:Class ; rdfs:label "His-Purkinje system cell" ; rdfs:subClassOf obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004146 ] ) ] . obo:CL_0010008 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "cardiac endothelial cell" ; rdfs:subClassOf obo:CL_0000115, obo:CL_0002494, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000948 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000948 ] ) ] . obo:CL_0010009 oboInOwl:hasExactSynonym "camera type eye photoreceptor cell" ; a owl:Class ; rdfs:label "camera-type eye photoreceptor cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000287, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000210 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000019 ] ) ] . obo:CL_0010017 obo:IAO_0000115 "A zygote in a plant or an animal." ; oboInOwl:hasDbXref "MESH:D015053" ; a owl:Class ; rdfs:label "zygote"@en ; rdfs:seeAlso ; rdfs:subClassOf obo:CL_0000003 . obo:CL_0010020 a owl:Class ; rdfs:label "cardiac glial cell" ; rdfs:subClassOf obo:CL_0000125, obo:CL_0002494, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000948 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000125 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000948 ] ) ] . obo:CL_0010021 oboInOwl:hasDbXref "MESH:D032386" ; a owl:Class ; rdfs:label "cardiac myoblast" ; rdfs:subClassOf obo:CL_0000056, [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0000746 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000056 [ a owl:Restriction ; owl:onProperty obo:RO_0002203 ; owl:someValuesFrom obo:CL_0000746 ] ) ] . obo:CL_0010022 obo:IAO_0000115 "A neuron that has its soma in the heart." ; a owl:Class ; rdfs:comment "This term is used in 3 GO terms that were created as part of the heart development focus project." ; rdfs:label "cardiac neuron" ; rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/pull/1488" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0000948 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0000948 ] ) ] . obo:CL_0011001 obo:IAO_0000115 "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." ; a owl:Class ; rdfs:label "spinal cord motor neuron" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000100, obo:CL_2000029, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002240 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000100 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002240 ] ) ] . obo:CL_0011005 obo:IAO_0000115 "An interneuron that uses GABA as a vesicular neurotransmitter. These interneurons are inhibitory" ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasExactSynonym "GABAergic inhibitory interneuron" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "The formal and textual definitions of this term will need to be altered if evidence for non-inhibitory GABA-ergic neurons emerges." ; rdfs:label "GABAergic interneuron" ; rdfs:subClassOf obo:CL_0000498, obo:CL_0000617 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000099 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0061534 ] ) ] . obo:CL_0011007 obo:IAO_0000115 "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites." ; oboInOwl:hasExactSynonym "paraxial mesoderm cell", "somitic mesoderm cell" ; oboInOwl:hasNarrowSynonym "presomitic mesoderm cell" ; a owl:Class ; rdfs:label "paraxial cell" ; rdfs:subClassOf obo:CL_0000222, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000222 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003059 ] ) ] . obo:CL_0011012 obo:IAO_0000115 "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells." ; a owl:Class ; rdfs:label "neural crest cell" ; rdfs:subClassOf obo:CL_0000048, obo:CL_0002321 . obo:CL_0011013 obo:IAO_0000115 "A sperm cell that is cabaple of motion (motility)." ; terms:contributor ; a owl:Class ; rdfs:label "motile sperm cell" ; rdfs:subClassOf obo:CL_0000019, obo:CL_0000219, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0097722 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000019 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0097722 ] ) ] . obo:CL_0011016 obo:IAO_0000115 "A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion." ; terms:contributor ; a owl:Class ; rdfs:label "flagellated sperm cell" ; rdfs:subClassOf obo:CL_0011013, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030317 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0011013 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030317 ] ) ] . obo:CL_0011019 obo:IAO_0000115 "A mesothelial cell that is part of the epicardium." ; terms:contributor ; a owl:Class ; rdfs:label "mesothelial cell of epicardium" ; rdfs:subClassOf obo:CL_0000077, obo:CL_0002494, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002348 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002348 ] ) ] . obo:CL_0011021 obo:IAO_0000115 "A fibroblast that is part of upper back skin." ; terms:contributor ; a owl:Class ; rdfs:label "fibroblast of upper back skin" ; rdfs:subClassOf obo:CL_0011022, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0009015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0009015 ] ) ] . obo:CL_0011022 obo:IAO_0000115 "A fibroblast that is part of skin of back." ; terms:contributor ; a owl:Class ; rdfs:label "fibroblast of skin of back" ; rdfs:subClassOf obo:CL_0002620, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001068 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001068 ] ) ] . obo:CL_0011026 obo:IAO_0000115 "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses." ; terms:contributor ; a owl:Class ; rdfs:label "progenitor cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0011115, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000034 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0011115 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000034 ] ) ] . obo:CL_0011027 obo:IAO_0000115 "Any fibroblast that is part of skeletal muscle tissue." ; terms:contributor ; oboInOwl:hasExactSynonym "skeleton muscle fibroblast" ; a owl:Class ; rdfs:label "skeletal muscle fibroblast" ; rdfs:subClassOf obo:CL_0000188, obo:CL_1001609 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001134 ] ) ] . obo:CL_0011030 obo:IAO_0000115 "Any microvascular endothelial cell that is part of the dermis." ; terms:contributor ; oboInOwl:hasExactSynonym "DMEC cell", "dermal microvascular endothelium cell" ; a owl:Class ; rdfs:label "dermal microvascular endothelial cell" ; rdfs:subClassOf obo:CL_2000008, obo:CL_2000010 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_2000008 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002067 ] ) ] . obo:CL_0011101 obo:IAO_0000115 "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." ; a owl:Class ; rdfs:label "chorionic trophoblast cell" ; rdfs:subClassOf obo:CL_0000351, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003124 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000351 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003124 ] ) ] . obo:CL_0011108 obo:IAO_0000115 "Epithelial cell that is part of the colon epithelium." ; oboInOwl:hasExactSynonym "colonic epithelial cell" ; a owl:Class ; rdfs:label "colon epithelial cell" ; rdfs:subClassOf obo:CL_0002253, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000397 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001155 ] ) ] . obo:CL_0011115 obo:IAO_0000115 "A cell that, by division or terminal differentiation, can give rise to other cell types." ; a owl:Class ; rdfs:comment "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ; rdfs:label "precursor cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030154 ] ) ] . obo:CL_0017500 obo:IAO_0000115 "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain." ; terms:contributor ; oboInOwl:creation_date "2010-05-25T01:36:34Z" ; a owl:Class ; rdfs:label "neutrophillic cytoplasm" ; rdfs:subClassOf obo:GO_0005737, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0070046 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0070046 ] ) ] . obo:CL_0017502 obo:IAO_0000115 "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain." ; terms:contributor ; oboInOwl:creation_date "2009-12-22T04:23:25Z" ; oboInOwl:hasNarrowSynonym "eosinophilic" ; a owl:Class ; rdfs:label "acidophilic cytoplasm" ; rdfs:subClassOf obo:GO_0005737, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002418 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002418 ] ) ] . obo:CL_0017503 obo:IAO_0000115 "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions." ; terms:contributor ; oboInOwl:creation_date "2009-12-22T04:24:54Z" ; a owl:Class ; rdfs:label "basophilic cytoplasm" ; rdfs:subClassOf obo:GO_0005737, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002094 ] ) ] . obo:CL_0017504 obo:IAO_0000115 "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions." ; terms:contributor ; oboInOwl:creation_date "2009-12-28T04:25:23Z" ; a owl:Class ; rdfs:label "polychromatophilic cytoplasm" ; rdfs:subClassOf obo:GO_0005737, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0070047 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0070047 ] ) ] . obo:CL_0017505 obo:IAO_0000115 "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." ; terms:contributor ; oboInOwl:creation_date "2009-12-23T10:53:24Z" ; a owl:Class ; rdfs:label "increased nucleus size" ; rdfs:subClassOf obo:GO_0005634, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000586 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005634 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000586 ] ) ] . obo:CL_0019001 obo:IAO_0000115 "Any serous secreting cell that is part of the tracheobronchial epithelium." ; terms:contributor ; terms:date "2020-05-07T16:03:27Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "serous cell of tracheobronchial tree" ; oboInOwl:inSubset cl:added_for_HCA ; a owl:Class ; rdfs:label "tracheobronchial serous cell"@en ; rdfs:subClassOf obo:CL_0000313, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007196 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000313 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007196 ] ) ] . obo:CL_0019002 obo:IAO_0000115 "Any chondrocyte that is part of the tracheobronchial tree." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; terms:date "2020-05-07T17:29:51Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "chondrocyte of tracheobronchial tree" ; oboInOwl:inSubset cl:added_for_HCA, core:human_reference_atlas ; a owl:Class ; rdfs:label "tracheobronchial chondrocyte"@en ; rdfs:subClassOf obo:CL_0000138, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007196 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000138 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007196 ] ) ] . obo:CL_0019018 obo:IAO_0000115 "A smooth muscle cell that is part of any blood vessel." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; terms:date "2020-07-21T12:42:48Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "smooth muscle cell of blood vessel" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "blood vessel smooth muscle cell"@en ; rdfs:subClassOf obo:CL_0000359, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001981 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001981 ] ) ] . obo:CL_0019019 obo:IAO_0000115 "A smooth muscle cell that is part of the tracheobronchial tree." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; terms:date "2020-07-21T12:50:22Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "smooth muscle cell of tracheobronchial tree" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "tracheobronchial smooth muscle cell"@en ; rdfs:subClassOf obo:CL_0000192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007196 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007196 ] ) ] . obo:CL_0019020 obo:IAO_0000115 "An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes." ; terms:contributor ; terms:date "2020-09-03T12:24:24Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "large bile duct cholangiocyte" ; a owl:Class ; rdfs:label "extrahepatic cholangiocyte"@en ; rdfs:subClassOf obo:CL_1000488, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004822 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000488 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004822 ] ) ] . obo:CL_0019021 obo:IAO_0000115 "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid." ; terms:contributor ; terms:date "2020-09-09T13:56:47Z"^^xsd:dateTime ; oboInOwl:hasDbXref "EFO:0010705" ; oboInOwl:hasExactSynonym "periportal LSEC", "periportal hepatic sinusoidal endothelial cell" ; a owl:Class ; rdfs:label "endothelial cell of periportal hepatic sinusoid"@en ; rdfs:subClassOf obo:CL_1000398, [ a owl:Restriction ; owl:onProperty obo:RO_0002220 ; owl:someValuesFrom obo:UBERON_0001279 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000398 [ a owl:Restriction ; owl:onProperty obo:RO_0002220 ; owl:someValuesFrom obo:UBERON_0001279 ] ) ] . obo:CL_0019022 obo:IAO_0000115 "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid." ; terms:contributor ; terms:date "2020-09-10T12:38:29Z"^^xsd:dateTime ; oboInOwl:hasDbXref "EFO:0010706" ; oboInOwl:hasExactSynonym "central venous hepatic sinusoidal endothelial cell", "pericentral LSEC" ; a owl:Class ; rdfs:label "endothelial cell of pericentral hepatic sinusoid"@en ; rdfs:subClassOf obo:CL_1000398, [ a owl:Restriction ; owl:onProperty obo:RO_0002220 ; owl:someValuesFrom obo:UBERON_0006841 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000398 [ a owl:Restriction ; owl:onProperty obo:RO_0002220 ; owl:someValuesFrom obo:UBERON_0006841 ] ) ] . obo:CL_1000090 a owl:Class ; rdfs:label "pronephric nephron tubule epithelial cell" ; rdfs:subClassOf obo:CL_1000449, obo:CL_1000507, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005310 ] ) ] . obo:CL_1000123 a owl:Class ; rdfs:label "metanephric nephron tubule epithelial cell" ; rdfs:subClassOf obo:CL_1000449, obo:CL_1000507, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005146 ] ) ] . obo:CL_1000222 a owl:Class ; rdfs:label "stomach neuroendocrine cell" ; rdfs:subClassOf obo:CL_0000164, obo:CL_0000165, obo:CL_0002659 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000165 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000945 ] ) ] . obo:CL_1000223 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "lung neuroendocrine cell" ; rdfs:subClassOf obo:CL_0000082, obo:CL_0000165, obo:CL_1000272 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000165 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_1000271 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "lung ciliated cell" ; rdfs:subClassOf obo:CL_0000548, obo:CL_4030034, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000064 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_1000272 a owl:Class ; rdfs:label "lung secretory cell" ; rdfs:subClassOf obo:CL_0000151, obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_1000274 oboInOwl:hasExactSynonym "trophectoderm cell" ; a owl:Class ; rdfs:label "trophectodermal cell" ; rdfs:subClassOf obo:CL_0000349 . obo:CL_1000275 obo:IAO_0000115 "A smooth muscle cell that is part of the small intestine." ; oboInOwl:hasDbXref "FMA:15050" ; oboInOwl:hasExactSynonym "non-striated muscle fiber of small intestine" ; a owl:Class ; rdfs:label "smooth muscle cell of small intestine" ; rdfs:subClassOf obo:CL_0002504, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002108 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002504 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002108 ] ) ] . obo:CL_1000276 obo:IAO_0000115 "A smooth muscle cell that is part of the duodenum." ; oboInOwl:hasDbXref "FMA:15058" ; oboInOwl:hasExactSynonym "non-striated muscle fiber of duodenum" ; a owl:Class ; rdfs:label "smooth muscle fiber of duodenum" ; rdfs:subClassOf obo:CL_1000275, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002114 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000275 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002114 ] ) ] . obo:CL_1000279 obo:IAO_0000115 "A smooth muscle cell that is part of the large intestine." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:15653" ; oboInOwl:hasExactSynonym "non-striated muscle fiber of large intestine" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "smooth muscle cell of large intestine" ; rdfs:subClassOf obo:CL_0002504, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002504 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000059 ] ) ] . obo:CL_1000280 obo:IAO_0000115 "A smooth muscle cell that is part of the colon." ; oboInOwl:hasDbXref "FMA:15663" ; oboInOwl:hasExactSynonym "non-striated muscle fiber of colon" ; a owl:Class ; rdfs:label "smooth muscle cell of colon" ; rdfs:subClassOf obo:CL_1000279, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002504 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001155 ] ) ] . obo:CL_1000285 obo:IAO_0000115 "A smooth muscle cell that is part of the sigmoid colon." ; oboInOwl:hasDbXref "FMA:17521" ; oboInOwl:hasExactSynonym "non-striated muscle fiber of sigmoid colon" ; a owl:Class ; rdfs:label "smooth muscle cell of sigmoid colon" ; rdfs:subClassOf obo:CL_1000280, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001159 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000280 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001159 ] ) ] . obo:CL_1000286 obo:IAO_0000115 "A smooth muscle cell that is part of the rectum." ; oboInOwl:hasDbXref "FMA:17522" ; oboInOwl:hasExactSynonym "non-striated muscle fiber of rectum", "smooth muscle fiber of rectum" ; a owl:Class ; rdfs:label "smooth muscle cell of rectum" ; rdfs:subClassOf obo:CL_1000279, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001052 ] ) ] . obo:CL_1000296 obo:IAO_0000115 "An epithelial cell that is part of the urethra." ; oboInOwl:hasDbXref "FMA:256165" ; a owl:Class ; rdfs:label "epithelial cell of urethra" ; rdfs:subClassOf obo:CL_0000066, obo:CL_0002371, obo:CL_1001320 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000057 ] ) ] . obo:CL_1000303 obo:IAO_0000115 "A fibroblast that is part of the areolar connective tissue." ; oboInOwl:hasDbXref "FMA:261279" ; a owl:Class ; rdfs:label "fibroblast of areolar connective tissue" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0006815 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0006815 ] ) ] . obo:CL_1000306 obo:IAO_0000115 "A fibroblast that is part of the tunica adventitia of artery." ; oboInOwl:hasDbXref "FMA:261285" ; a owl:Class ; rdfs:label "fibroblast of tunica adventitia of artery" ; rdfs:subClassOf obo:CL_0000057, obo:CL_0002503, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005734 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005734 ] ) ] . obo:CL_1000307 obo:IAO_0000115 "A fibroblast that is part of the dense regular elastic tissue." ; oboInOwl:hasDbXref "FMA:261287" ; a owl:Class ; rdfs:label "fibroblast of dense regular elastic tissue" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002521 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007846 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0007846 ] ) ] . obo:CL_1000309 obo:IAO_0000115 "A fat cell that is part of the epicardial fat." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:261293" ; oboInOwl:hasExactSynonym "adipocyte of epicardial fat", "epicardial fat cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "epicardial adipocyte" ; rdfs:subClassOf obo:CL_0000136, obo:CL_0002494, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002348 ] . obo:CL_1000310 obo:IAO_0000115 "A fat cell that is part of the epicardial fat of right ventricle." ; oboInOwl:hasDbXref "FMA:261297" ; oboInOwl:hasExactSynonym "epicardial adipocyte of right ventricle", "epicardial fat cell of right ventricle" ; a owl:Class ; rdfs:label "adipocyte of epicardial fat of right ventricle" ; rdfs:subClassOf obo:CL_1000309, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002080 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000309 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002080 ] ) ] . obo:CL_1000311 obo:IAO_0000115 "A fat cell that is part of the epicardial fat of left ventricle." ; oboInOwl:hasDbXref "FMA:261300" ; oboInOwl:hasExactSynonym "epicardial adipocyte of left ventricle", "epicardial fat cell of left ventricle" ; a owl:Class ; rdfs:label "adipocyte of epicardial fat of left ventricle" ; rdfs:subClassOf obo:CL_1000309, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000309 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002084 ] ) ] . obo:CL_1000330 obo:IAO_0000115 "A serous secreting cell that is part of the epithelium of trachea." ; oboInOwl:hasDbXref "FMA:263078" ; a owl:Class ; rdfs:label "serous cell of epithelium of trachea" ; rdfs:subClassOf obo:CL_0019001, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001901 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000313 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001901 ] ) ] . obo:CL_1000331 obo:IAO_0000115 "A serous secreting cell that is part of the epithelium of bronchus." ; oboInOwl:hasDbXref "FMA:263080" ; a owl:Class ; rdfs:label "serous cell of epithelium of bronchus" ; rdfs:subClassOf obo:CL_0019001, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000313 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002031 ] ) ] . obo:CL_1000332 obo:IAO_0000115 "A serous secreting cell that is part of the epithelium of terminal bronchiole." ; oboInOwl:hasDbXref "FMA:263082" ; a owl:Class ; rdfs:label "serous cell of epithelium of terminal bronchiole" ; rdfs:subClassOf obo:CL_0019001, obo:CL_1000272, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001958 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000313 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001958 ] ) ] . obo:CL_1000361 obo:IAO_0000115 "A transitional myocyte that is part of the interatrial septum." ; oboInOwl:hasDbXref "FMA:263152" ; a owl:Class ; rdfs:label "transitional myocyte of interatrial septum" ; rdfs:subClassOf obo:CL_0002073, obo:CL_2000022, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002073 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002085 ] ) ] . obo:CL_1000362 obo:IAO_0000115 "A transitional myocyte that is part of the interventricular septum." ; oboInOwl:hasDbXref "FMA:263154" ; a owl:Class ; rdfs:label "transitional myocyte of interventricular septum" ; rdfs:subClassOf obo:CL_0002073, obo:CL_2000022, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002073 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002094 ] ) ] . obo:CL_1000376 obo:IAO_0000115 "A Purkinje myocyte that is part of the interventricular septum." ; oboInOwl:hasDbXref "FMA:263182" ; a owl:Class ; rdfs:label "Purkinje myocyte of interventricular septum" ; rdfs:subClassOf obo:CL_0002068, obo:CL_2000022, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002068 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002094 ] ) ] . obo:CL_1000398 obo:IAO_0000115 "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:000125", "FMA:62911" ; oboInOwl:hasExactSynonym "LSEC", "endotheliocyte of hepatic sinusoid", "liver sinusoidal endothelial cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "endothelial cell of hepatic sinusoid" ; rdfs:subClassOf obo:CL_0002262, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001281 ] ) ] . obo:CL_1000409 obo:IAO_0000115 "A muscle cell that is part of the sinoatrial node." ; oboInOwl:hasDbXref "FMA:67102" ; oboInOwl:hasExactSynonym "SA nodal myocyte", "SA node cardiac muscle cell", "myocyte of sinoatrial node", "sinoatrial node cell", "sinoatrial node myocyte", "sinuatrial node myocyte" ; a owl:Class ; rdfs:label "myocyte of sinoatrial node" ; rdfs:subClassOf obo:CL_0002072, obo:CL_0008009, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000187 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002351 ] ) ] . obo:CL_1000410 obo:IAO_0000115 "A muscle cell that is part of the atrioventricular node." ; oboInOwl:hasDbXref "FMA:67106" ; oboInOwl:hasExactSynonym "AV nodal myocyte", "AV node cardiac muscle cell", "AV node cell", "atrioventricular node cell", "atrioventricular node myocyte" ; a owl:Class ; rdfs:label "myocyte of atrioventricular node" ; rdfs:subClassOf obo:CL_0002072, obo:CL_0008009, obo:CL_2000022, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002352 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000187 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002352 ] ) ] . obo:CL_1000412 obo:IAO_0000115 "An endothelial cell that is part of the arteriole." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:67760", "KUPO:0001097" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "endothelial cell of arteriole" ; rdfs:subClassOf obo:CL_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001980 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001980 ] ) ] . obo:CL_1000413 obo:IAO_0000115 "A blood vessel endothelial cell that is part of an arterial endothelium." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0004758", "FMA:67761", "KUPO:0001095" ; oboInOwl:hasExactSynonym "arterial endothelial cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "endothelial cell of artery" ; rdfs:subClassOf obo:CL_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001917 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001637 ] ) ] . obo:CL_1000414 obo:IAO_0000115 "An endothelial cell that is part of the venule." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:67762" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "endothelial cell of venule" ; rdfs:subClassOf obo:CL_0002139, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001979 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002139 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001979 ] ) ] . obo:CL_1000415 obo:IAO_0000115 "An epithelial cell that is part of the gallbladder." ; oboInOwl:hasDbXref "FMA:67780" ; a owl:Class ; rdfs:label "epithelial cell of gallbladder" ; rdfs:subClassOf obo:CL_0000066, obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002110 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002110 ] ) ] . obo:CL_1000428 obo:IAO_0000115 "A somatic stem cell that is part of the epidermis." ; oboInOwl:hasDbXref "FMA:70541" ; oboInOwl:hasExactSynonym "epidermal stem cell" ; a owl:Class ; rdfs:label "stem cell of epidermis" ; rdfs:subClassOf obo:CL_0000723, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000723 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001003 ] ) ] . obo:CL_1000443 obo:IAO_0000115 "A smooth muscle cell that is part of the ciliary body." ; oboInOwl:hasDbXref "FMA:70610" ; oboInOwl:hasExactSynonym "smooth muscle cell of ciliary body" ; a owl:Class ; rdfs:label "ciliary muscle cell" ; rdfs:subClassOf obo:CL_0000192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001775 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001775 ] ) ] . obo:CL_1000444 obo:IAO_0000115 "A mesothelial cell that is part of the anterior chamber of eyeball." ; oboInOwl:hasDbXref "FMA:70615" ; a owl:Class ; rdfs:label "mesothelial cell of anterior chamber of eye" ; rdfs:subClassOf obo:CL_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001766 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001766 ] ) ] . obo:CL_1000449 obo:IAO_0000115 "An epithelial cell that is part of the nephron." ; oboInOwl:hasDbXref "FMA:70965" ; a owl:Class ; rdfs:label "epithelial cell of nephron" ; rdfs:subClassOf obo:CL_0002518, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001285 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001285 ] ) ] . obo:CL_1000454 obo:IAO_0000115 "An epithelial cell that is part of the collecting duct of renal tubule." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:70982", "KUPO:0001059" ; oboInOwl:hasExactSynonym "epithelial cell of renal collecting tubule" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "kidney collecting duct epithelial cell" ; rdfs:subClassOf obo:CL_0000072, obo:CL_1000449, obo:CL_1001225 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000072 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001232 ] ) ] . obo:CL_1000456 obo:IAO_0000115 "A mesothelial cell that is part of the parietal peritoneum." ; oboInOwl:hasDbXref "FMA:72142" ; a owl:Class ; rdfs:label "mesothelial cell of parietal peritoneum" ; rdfs:subClassOf obo:CL_1000490, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001366 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001366 ] ) ] . obo:CL_1000457 obo:IAO_0000115 "A mesothelial cell that is part of the visceral peritoneum." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:72143" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "mesothelial cell of visceral peritoneum" ; rdfs:subClassOf obo:CL_1000490, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001178 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001178 ] ) ] . obo:CL_1000478 obo:IAO_0000115 "A transitional myocyte that is part of the sinoatrial node." ; oboInOwl:hasDbXref "FMA:83384" ; oboInOwl:hasExactSynonym "transitinal myocyte of sinuatrial node" ; a owl:Class ; rdfs:label "transitional myocyte of sinoatrial node" ; rdfs:subClassOf obo:CL_0002073, obo:CL_1000409 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002073 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002351 ] ) ] . obo:CL_1000479 obo:IAO_0000115 "A Purkinje myocyte that is part of the atrioventricular node." ; oboInOwl:hasDbXref "FMA:83386" ; a owl:Class ; rdfs:label "Purkinje myocyte of atrioventricular node" ; rdfs:subClassOf obo:CL_0002068, obo:CL_1000410 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002068 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002352 ] ) ] . obo:CL_1000482 obo:IAO_0000115 "A myocardial endocrine cell that is part of the interventricular septum." ; oboInOwl:hasDbXref "FMA:83390" ; a owl:Class ; rdfs:label "myocardial endocrine cell of interventricular septum" ; rdfs:subClassOf obo:CL_0002074, obo:CL_2000022, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002074 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002094 ] ) ] . obo:CL_1000488 obo:IAO_0000115 "An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts." ; oboInOwl:hasDbXref "FMA:86481" ; oboInOwl:hasExactSynonym "epithelial cell of bile duct" ; a owl:Class ; rdfs:label "cholangiocyte" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000069, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002394 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0005026 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0015106 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032782 ] ) ] ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000069 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002394 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0015106 ] ) ] . obo:CL_1000490 obo:IAO_0000115 "A mesothelial cell that is part of the peritoneum." ; oboInOwl:hasDbXref "FMA:86736" ; oboInOwl:hasExactSynonym "peritoneal mesothelial cell" ; a owl:Class ; rdfs:label "mesothelial cell of peritoneum" ; rdfs:subClassOf obo:CL_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002358 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002358 ] ) ] . obo:CL_1000491 obo:IAO_0000115 "A mesothelial cell that is part of the pleura." ; oboInOwl:hasDbXref "FMA:86737" ; oboInOwl:hasExactSynonym "pleural mesothelial cell" ; a owl:Class ; rdfs:label "mesothelial cell of pleura" ; rdfs:subClassOf obo:CL_0000077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000977 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000977 ] ) ] . obo:CL_1000492 obo:IAO_0000115 "A mesothelial cell that is part of the parietal pleura." ; oboInOwl:hasDbXref "FMA:86738" ; a owl:Class ; rdfs:label "mesothelial cell of parietal pleura" ; rdfs:subClassOf obo:CL_1000491, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002400 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002400 ] ) ] . obo:CL_1000493 obo:IAO_0000115 "A mesothelial cell that is part of the visceral pleura." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:86739" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "mesothelial cell of visceral pleura" ; rdfs:subClassOf obo:CL_0000082, obo:CL_1000491, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002401 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002401 ] ) ] . obo:CL_1000494 obo:IAO_0000115 "An epithelial cell that is part of a nephron tubule." ; oboInOwl:hasDbXref "FMA:86785", "KUPO:0001022" ; oboInOwl:hasExactSynonym "kidney tubule epithelial cell" ; a owl:Class ; rdfs:comment "This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON." ; rdfs:label "nephron tubule epithelial cell" ; rdfs:subClassOf obo:CL_1000449, obo:CL_1000507, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004810 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004810 ] ) ] . obo:CL_1000497 oboInOwl:hasDbXref "KUPO:0001010" ; a owl:Class ; rdfs:label "kidney cell" ; rdfs:subClassOf obo:CL_0002371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002113 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000548 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002113 ] ) ] . obo:CL_1000500 oboInOwl:hasDbXref "KUPO:0001013" ; a owl:Class ; rdfs:label "kidney interstitial cell" ; rdfs:subClassOf obo:CL_1000497, obo:CL_4030031, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005215 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000497 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005215 ] ) ] . obo:CL_1000505 oboInOwl:hasDbXref "KUPO:0001018" ; a owl:Class ; rdfs:label "kidney pelvis cell" ; rdfs:subClassOf obo:CL_1000497, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001224 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000497 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001224 ] ) ] . obo:CL_1000507 oboInOwl:hasDbXref "KUPO:0001020" ; a owl:Class ; rdfs:label "kidney tubule cell" ; rdfs:subClassOf obo:CL_1000497, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000497 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001231 ] ) ] . obo:CL_1000549 oboInOwl:hasDbXref "KUPO:0001063" ; a owl:Class ; rdfs:label "kidney cortex collecting duct epithelial cell" ; rdfs:subClassOf obo:CL_0002681, obo:CL_1001225, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004203 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000497 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004203 ] ) ] . obo:CL_1000600 oboInOwl:hasDbXref "KUPO:0001115" ; a owl:Class ; rdfs:label "lower urinary tract cell" ; rdfs:subClassOf obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000548 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001556 ] ) ] . obo:CL_1000601 oboInOwl:hasDbXref "KUPO:0001116" ; a owl:Class ; rdfs:label "ureteral cell" ; rdfs:subClassOf obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000548 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000056 ] ) ] . obo:CL_1000606 oboInOwl:hasDbXref "KUPO:0001015" ; a owl:Class ; rdfs:label "kidney nerve cell" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_1000500, obo:CL_2000032, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002113 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002113 ] ) ] . obo:CL_1000681 oboInOwl:hasDbXref "KUPO:0001091" ; a owl:Class ; rdfs:label "kidney cortex interstitial cell" ; rdfs:subClassOf obo:CL_0002584, obo:CL_1000500, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005270 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000500 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005270 ] ) ] . obo:CL_1000692 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "KUPO:0001102" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "kidney interstitial fibroblast" ; rdfs:subClassOf obo:CL_0000057, obo:CL_1000500 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005215 ] ) ] . obo:CL_1000702 oboInOwl:hasDbXref "KUPO:0001113" ; a owl:Class ; rdfs:label "kidney pelvis smooth muscle cell" ; rdfs:subClassOf obo:CL_0000192, obo:CL_1000505, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004227 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004227 ] ) ] . obo:CL_1000708 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "KUPO:0001119" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "ureter adventitial cell" ; rdfs:subClassOf obo:CL_0000115, obo:CL_0002503, obo:CL_1000601, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001252 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000601 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001252 ] ) ] . obo:CL_1000714 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "KUPO:0001130" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "kidney cortex collecting duct principal cell" ; rdfs:subClassOf obo:CL_0002584, obo:CL_1000549, obo:CL_1001431 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0005009 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004203 ] ) ] . obo:CL_1000979 oboInOwl:hasDbXref "KUPO:0001118" ; a owl:Class ; rdfs:label "ureter smooth muscle cell" ; rdfs:subClassOf obo:CL_0000192, obo:CL_1000601, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0006855 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0006855 ] ) ] . obo:CL_1001225 oboInOwl:hasDbXref "KUPO:0001012", "Wikipedia:Kidney_collecting_duct_cell" ; a owl:Class ; rdfs:label "kidney collecting duct cell" ; rdfs:subClassOf obo:CL_1000497, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001232 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000497 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001232 ] ) ] . obo:CL_1001319 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "KUPO:0001120" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "bladder cell" ; rdfs:subClassOf obo:CL_1000600, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001255 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000548 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001255 ] ) ] . obo:CL_1001320 oboInOwl:hasDbXref "KUPO:0001123" ; a owl:Class ; rdfs:label "urethra cell" ; rdfs:subClassOf obo:CL_1000600, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000548 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000057 ] ) ] . obo:CL_1001431 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "KUPO:0001128" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "kidney collecting duct principal cell" ; rdfs:subClassOf obo:CL_0005009, obo:CL_1000454 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0005009 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001232 ] ) ] . obo:CL_1001433 obo:IAO_0000115 "An epithelial cell of the exocrine pancreas." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "FMA:70986" ; oboInOwl:hasExactSynonym "exocrine pancreas cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "epithelial cell of exocrine pancreas" ; rdfs:subClassOf obo:CL_0000083, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000017 ] ) ] . obo:CL_1001516 obo:IAO_0000115 "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract." ; a owl:Class ; rdfs:label "intestinal enteroendocrine cell" ; rdfs:subClassOf obo:CL_0000164, obo:CL_0002563 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000164 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001242 ] ) ] . obo:CL_1001567 oboInOwl:hasRelatedSynonym "endothelial cell of lung", "pulmonary vessel endothelial cell" ; a owl:Class ; rdfs:label "lung endothelial cell" ; rdfs:subClassOf obo:CL_0000082, obo:CL_0002139, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002139 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_1001568 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0001141" ; oboInOwl:hasRelatedSynonym "PAEC cell" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "pulmonary artery endothelial cell" ; rdfs:subClassOf obo:CL_1000413, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005317 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002139 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002012 ] ) ] . obo:CL_1001572 obo:IAO_0000115 "A vascular endothelial cell found in colon blood vessels." ; oboInOwl:hasDbXref "CALOHA:TS-2397" ; oboInOwl:hasRelatedSynonym "colon endothelial cells", "colonic endothelial cell" ; a owl:Class ; rdfs:label "colon endothelial cell" ; rdfs:subClassOf obo:CL_0000115, obo:CL_0011108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0013695 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001155 ] ) ] . obo:CL_1001576 obo:IAO_0000115 "Squamous cell of oral epithelium." ; oboInOwl:hasDbXref "CALOHA:TS-1252" ; oboInOwl:hasRelatedSynonym "oral cavity mucosa squamous cell", "oral cavity mucosa squamous epithelial cell", "oral mucosa squamous epithelial cell", "oral mucosa squamous epithelial cells" ; a owl:Class ; rdfs:label "oral mucosa squamous cell" ; rdfs:subClassOf obo:CL_0000076, obo:CL_0002251, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002424 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000076 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002424 ] ) ] . obo:CL_1001588 obo:IAO_0000115 "Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells." ; oboInOwl:hasDbXref "CALOHA:TS-1274" ; oboInOwl:hasRelatedSynonym "colon glandular cells" ; a owl:Class ; rdfs:label "colon glandular cell" ; rdfs:subClassOf obo:CL_0002658, obo:CL_0011108 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001155 ] ) ] . obo:CL_1001589 obo:IAO_0000115 "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell." ; oboInOwl:hasDbXref "CALOHA:TS-1275" ; oboInOwl:hasRelatedSynonym "duodenum glandular cells" ; a owl:Class ; rdfs:label "duodenum glandular cell" ; rdfs:subClassOf obo:CL_1001598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0008346 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002114 ] ) ] . obo:CL_1001590 obo:IAO_0000115 "Glandular cell of epididymal epithelium." ; oboInOwl:hasDbXref "CALOHA:TS-1276" ; oboInOwl:hasRelatedSynonym "epididymal glandular cell", "epididymis glandular cells" ; a owl:Class ; rdfs:label "epididymis glandular cell" ; rdfs:subClassOf obo:CL_0000068, obo:CL_0000150, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004544 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001301 ] ) ] . obo:CL_1001591 obo:IAO_0000115 "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells." ; oboInOwl:hasDbXref "CALOHA:TS-1277" ; oboInOwl:hasRelatedSynonym "fallopian tube glandular cell", "fallopian tube glandular cells", "uterine tube glandular cell" ; a owl:Class ; rdfs:label "oviduct glandular cell" ; rdfs:subClassOf obo:CL_0000150, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004804 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000993 ] ) ] . obo:CL_1001592 obo:IAO_0000115 "Glandular cell of gallbladder epithelium." ; oboInOwl:hasDbXref "CALOHA:TS-1278" ; oboInOwl:hasExactSynonym "gall bladder glandular cell" ; oboInOwl:hasRelatedSynonym "gall bladder glandular cells", "gallbladder glandular cells" ; a owl:Class ; rdfs:label "gallbladder glandular cell" ; rdfs:subClassOf obo:CL_0000150, obo:CL_1000415, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002029 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002110 ] ) ] . obo:CL_1001595 obo:IAO_0000115 "Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells." ; oboInOwl:hasDbXref "CALOHA:TS-1281" ; oboInOwl:hasRelatedSynonym "rectal glandular cell", "rectum glandular cells" ; a owl:Class ; rdfs:label "rectum glandular cell" ; rdfs:subClassOf obo:CL_0002658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003354 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001052 ] ) ] . obo:CL_1001597 obo:IAO_0000115 "Glandular cell of seminal vesicle epithelium." ; oboInOwl:hasDbXref "CALOHA:TS-1283" ; oboInOwl:hasRelatedSynonym "seminal vesicle glandular cells" ; a owl:Class ; rdfs:label "seminal vesicle glandular cell" ; rdfs:subClassOf obo:CL_0000068, obo:CL_0000150, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004805 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000998 ] ) ] . obo:CL_1001598 obo:IAO_0000115 "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) ." ; oboInOwl:hasDbXref "CALOHA:TS-1286", "FMA:86928" ; oboInOwl:hasRelatedSynonym "small bowel glandular cell", "small intestinal glandular cell", "small intestine glandular cells" ; a owl:Class ; rdfs:label "small intestine glandular cell" ; rdfs:subClassOf obo:CL_0000150, obo:CL_0002254, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002108 ] ) ] . obo:CL_1001599 obo:IAO_0000115 "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000028", "CALOHA:TS-1242" ; oboInOwl:hasRelatedSynonym "exocrine pancreas glandular cell", "pancreas exocrine glandular cells" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "pancreas exocrine glandular cell" ; rdfs:subClassOf obo:CL_0000150, obo:CL_0000152, obo:CL_1001433, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0013697 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000017 ] ) ] . obo:CL_1001609 obo:IAO_0000115 "Fibroblast from muscle organ." ; oboInOwl:hasDbXref "CALOHA:TS-0643" ; a owl:Class ; rdfs:label "muscle fibroblast" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001630 ] ) ] . obo:CL_1001610 obo:IAO_0000115 "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes." ; oboInOwl:hasDbXref "CALOHA:TS-2109" ; oboInOwl:hasRelatedSynonym "bone marrow hematopoietic cells", "bone marrow poietic cells" ; a owl:Class ; rdfs:label "bone marrow hematopoietic cell" ; rdfs:subClassOf obo:CL_0000988, obo:CL_0002092, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0012429 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000988 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002371 ] ) ] . obo:CL_2000001 obo:IAO_0000115 "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood." ; terms:contributor ; oboInOwl:creation_date "2014-02-11T17:29:04Z" ; oboInOwl:id "CL:2000001" ; a owl:Class ; rdfs:label "peripheral blood mononuclear cell" ; rdfs:subClassOf obo:CL_0000080, obo:CL_0000842, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000178 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000842 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000178 ] ) ] . obo:CL_2000002 obo:IAO_0000115 "A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization." ; oboInOwl:creation_date "2014-02-20T23:06:41Z" ; oboInOwl:hasDbXref "BTO:0002770", "BTO:0005756", "NCIT:C32429" ; oboInOwl:hasExactSynonym "decidua cell", "decidual stromal cell" ; oboInOwl:id "CL:2000002" ; a owl:Class ; rdfs:label "decidual cell" ; rdfs:subClassOf obo:CL_0000349, obo:CL_0000499, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002450 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0002255 ] . obo:CL_2000008 obo:IAO_0000115 "Any blood vessel endothelial cell that is part of a microvascular endothelium." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2014-06-04T15:07:42Z" ; oboInOwl:id "CL:2000008" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "microvascular endothelial cell" ; rdfs:subClassOf obo:CL_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0008339 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000071 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0008339 ] ) ] . obo:CL_2000010 obo:IAO_0000115 "Any blood vessel endothelial cell that is part of a dermis." ; terms:contributor ; oboInOwl:creation_date "2014-06-04T15:12:06Z" ; oboInOwl:id "CL:2000010" ; a owl:Class ; rdfs:label "dermis blood vessel endothelial cell" ; rdfs:subClassOf obo:CL_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002067 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000071 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002067 ] ) ] . obo:CL_2000013 obo:IAO_0000115 "Any skin fibroblast that is part of a skin of abdomen." ; terms:contributor ; oboInOwl:creation_date "2014-06-04T15:18:16Z" ; oboInOwl:id "CL:2000013" ; a owl:Class ; rdfs:label "fibroblast of skin of abdomen" ; rdfs:subClassOf obo:CL_0002620, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002620 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001416 ] ) ] . obo:CL_2000016 obo:IAO_0000115 "Any lung endothelial cell that is part of a microvascular endothelium." ; terms:contributor ; oboInOwl:creation_date "2014-06-04T16:00:56Z" ; oboInOwl:id "CL:2000016" ; a owl:Class ; rdfs:label "lung microvascular endothelial cell" ; rdfs:subClassOf obo:CL_1001567, obo:CL_2000008 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1001567 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0008339 ] ) ] . obo:CL_2000019 obo:IAO_0000115 "Any photoreceptor cell that is part of a compound eye." ; terms:contributor ; oboInOwl:creation_date "2014-06-24T23:16:45Z" ; oboInOwl:hasDbXref "FBbt:00004211" ; oboInOwl:id "CL:2000019" ; a owl:Class ; rdfs:label "compound eye photoreceptor cell" ; rdfs:subClassOf obo:CL_0000287, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000018 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000210 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000018 ] ) ] . obo:CL_2000020 obo:IAO_0000115 "Any native cell that is part of a inner cell mass." ; terms:contributor ; oboInOwl:creation_date "2014-06-24T23:16:53Z" ; oboInOwl:id "CL:2000020" ; a owl:Class ; rdfs:label "inner cell mass cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000087 ] ) ] . obo:CL_2000022 obo:IAO_0000115 "Any native cell that is part of a cardiac septum." ; terms:contributor ; oboInOwl:creation_date "2014-06-24T23:17:07Z" ; oboInOwl:id "CL:2000022" ; a owl:Class ; rdfs:label "cardiac septum cell" ; rdfs:subClassOf obo:CL_0000548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002099 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002099 ] ) ] . obo:CL_2000029 obo:IAO_0000115 "Any neuron that is part of a central nervous system." ; terms:contributor ; oboInOwl:creation_date "2014-06-25T01:17:43Z" ; oboInOwl:id "CL:2000029" ; a owl:Class ; rdfs:label "central nervous system neuron" ; rdfs:subClassOf obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0001017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0001017 ] ) ] . obo:CL_2000032 obo:IAO_0000115 "A neuron that is part of a peripheral nervous system." ; terms:contributor ; oboInOwl:creation_date "2014-06-25T02:28:17Z" ; oboInOwl:hasDbXref "FMA:84664" ; oboInOwl:hasExactSynonym "PNS neuron", "peripheral neuron" ; oboInOwl:id "CL:2000032" ; a owl:Class ; rdfs:label "peripheral nervous system neuron" ; rdfs:subClassOf obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0000010 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0000010 ] ) ] . obo:CL_2000040 obo:IAO_0000115 "Any microvascular endothelial cell that is part of a urinary bladder." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2014-07-09T00:04:47Z" ; oboInOwl:id "CL:2000040" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "bladder microvascular endothelial cell" ; rdfs:subClassOf obo:CL_1001319, obo:CL_2000008 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_2000008 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001255 ] ) ] . obo:CL_2000042 obo:IAO_0000115 "Any fibroblast that is part of a embryo." ; terms:contributor ; oboInOwl:creation_date "2014-07-09T00:12:00Z" ; oboInOwl:id "CL:2000042" ; a owl:Class ; rdfs:label "embryonic fibroblast" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000922 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000922 ] ) ] . obo:CL_2000044 obo:IAO_0000115 "Any microvascular endothelial cell that is part of a brain." ; terms:contributor ; oboInOwl:creation_date "2014-07-09T00:24:53Z" ; oboInOwl:id "CL:2000044" ; a owl:Class ; rdfs:label "brain microvascular endothelial cell" ; rdfs:subClassOf obo:CL_0002319, obo:CL_2000008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_2000008 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000955 ] ) ] . obo:CL_2000046 obo:IAO_0000115 "Any cardiac muscle cell that is part of a cardiac ventricle." ; terms:contributor ; oboInOwl:creation_date "2014-08-12T20:50:28Z" ; oboInOwl:id "CL:2000046" ; a owl:Class ; rdfs:label "ventricular cardiac muscle cell" ; rdfs:subClassOf obo:CL_0000746, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000746 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002082 ] ) ] . obo:CL_2000047 obo:IAO_0000115 "Any motor neuron that is part of a brainstem." ; terms:contributor ; oboInOwl:creation_date "2014-10-02T23:52:53Z" ; oboInOwl:id "CL:2000047" ; a owl:Class ; rdfs:label "brainstem motor neuron" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000100, obo:CL_2000029, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002298 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000100 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0002298 ] ) ] . obo:CL_2000051 obo:IAO_0000115 "Any fibroblast that is part of a spleen." ; terms:contributor ; oboInOwl:creation_date "2014-10-06T18:58:47Z" ; oboInOwl:id "CL:2000051" ; a owl:Class ; rdfs:label "splenic fibroblast" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002106 ] ) ] . obo:CL_2000052 obo:IAO_0000115 "Any endothelial cell of artery that is part of a umbilical cord." ; terms:contributor ; oboInOwl:creation_date "2014-10-06T19:01:48Z" ; oboInOwl:id "CL:2000052" ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=8010" ; rdfs:label "umbilical artery endothelial cell" ; rdfs:subClassOf obo:CL_0000349, obo:CL_1000413, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002331 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_1000413 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002331 ] ) ] . obo:CL_2000053 obo:IAO_0000115 "Any endothelial cell that is part of a spleen." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2014-10-06T19:06:04Z" ; oboInOwl:id "CL:2000053" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=5500" ; rdfs:label "splenic endothelial cell" ; rdfs:subClassOf obo:CL_0000115, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000115 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002106 ] ) ] . obo:CL_2000055 obo:IAO_0000115 "Any dendritic cell that is part of a liver." ; terms:contributor ; oboInOwl:creation_date "2014-10-06T19:16:11Z" ; oboInOwl:hasExactSynonym "hepatic dendritic cell" ; oboInOwl:id "CL:2000055" ; a owl:Class ; rdfs:comment "http://www.jleukbio.org/content/66/2/322.abstract" ; rdfs:label "liver dendritic cell" ; rdfs:subClassOf obo:CL_0000451, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002107 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000451 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002107 ] ) ] . obo:CL_2000060 obo:IAO_0000115 "A trophoblast of placental villi. These cells fuse to form synctial trophoplast - the placental side of the interface between the placenta and maternal blood sinusoids in the decidua." ; terms:contributor ; oboInOwl:creation_date "2014-10-07T17:48:27Z" ; oboInOwl:hasDbXref "BTO:0006119", "BTO:0006208" ; oboInOwl:hasExactSynonym "vCTB", "villous cytotrophoblast" ; oboInOwl:id "CL:2000060" ; a owl:Class ; rdfs:comment "Same as synctial trophoblast?" ; rdfs:label "placental villous trophoblast" ; rdfs:seeAlso "http://www.sciencellonline.com/site/productInformation.php?keyword=7120" ; rdfs:subClassOf obo:CL_0000351, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0010005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000351 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0010005 ] ) ] . obo:CL_2000061 obo:IAO_0000115 "Any mesenchymal stem cell that is part of a placenta." ; terms:contributor ; oboInOwl:creation_date "2014-10-07T17:51:11Z" ; oboInOwl:id "CL:2000061" ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7140" ; rdfs:label "placental amniotic mesenchymal stromal cell" ; rdfs:subClassOf obo:CL_0000134, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000134 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001987 ] ) ] . obo:CL_2000062 obo:IAO_0000115 "Any capillary endothelial cell that is part of a placenta." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2014-10-07T17:55:56Z" ; oboInOwl:id "CL:2000062" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "http://www.ncbi.nlm.nih.gov/books/NBK53245/" ; rdfs:label "placental villus capillary endothelial cell" ; rdfs:subClassOf obo:CL_0002144, obo:CL_0009092, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0010005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002144 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0010005 ] ) ] . obo:CL_2000063 obo:IAO_0000115 "Any fibroblast that is part of a female gonad." ; terms:contributor ; oboInOwl:creation_date "2014-10-07T17:57:42Z" ; oboInOwl:id "CL:2000063" ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7330" ; rdfs:label "ovarian fibroblast" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000992 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000992 ] ) ] . obo:CL_2000064 obo:IAO_0000115 "Any epithelial cell that is part of a female gonad." ; terms:contributor ; oboInOwl:creation_date "2014-10-07T17:59:13Z" ; oboInOwl:id "CL:2000064" ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7310" ; rdfs:label "ovarian surface epithelial cell" ; rdfs:subClassOf obo:CL_0000066, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000992 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000992 ] ) ] . obo:CL_2000065 obo:IAO_0000115 "Any microvascular endothelial cell that is part of a female urethra." ; terms:contributor ; oboInOwl:creation_date "2014-10-07T18:18:01Z" ; oboInOwl:id "CL:2000065" ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7300" ; rdfs:label "ovarian microvascular endothelial cell" ; rdfs:subClassOf obo:CL_1000296, obo:CL_2000008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001334 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_2000008 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001334 ] ) ] . obo:CL_2000066 obo:IAO_0000115 "Any fibroblast that is part of a cardiac ventricle." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2014-10-07T18:35:38Z" ; oboInOwl:id "CL:2000066" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=6310" ; rdfs:label "cardiac ventricle fibroblast" ; rdfs:subClassOf obo:CL_0002548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002082 ] ) ] . obo:CL_2000067 obo:IAO_0000115 "Any fibroblast that is part of a cardiac atrium." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2014-10-07T18:36:54Z" ; oboInOwl:id "CL:2000067" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=6320" ; rdfs:label "cardiac atrium fibroblast" ; rdfs:subClassOf obo:CL_0002548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002081 ] ) ] . obo:CL_2000068 obo:IAO_0000115 "Any fibroblast that is part of a pericardium." ; terms:contributor ; oboInOwl:creation_date "2014-10-07T18:38:06Z" ; oboInOwl:id "CL:2000068" ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=6430" ; rdfs:label "pericardium fibroblast" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002407 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002407 ] ) ] . obo:CL_2000069 obo:IAO_0000115 "Any fibroblast that is part of a gallbladder." ; terms:contributor ; oboInOwl:creation_date "2014-10-07T18:41:43Z" ; oboInOwl:id "CL:2000069" ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=5430" ; rdfs:label "gallbladder fibroblast" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002110 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002110 ] ) ] . obo:CL_2000070 obo:IAO_0000115 "Any fibroblast that is part of a optic choroid." ; terms:contributor ; oboInOwl:creation_date "2014-10-07T18:50:43Z" ; oboInOwl:id "CL:2000070" ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=6620" ; rdfs:label "optic choroid fibroblast" ; rdfs:subClassOf obo:CL_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001776 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001776 ] ) ] . obo:CL_2000072 obo:IAO_0000115 "Any microvascular endothelial cell that is part of a adipose tissue." ; terms:contributor ; oboInOwl:creation_date "2014-10-07T22:13:45Z" ; oboInOwl:id "CL:2000072" ; a owl:Class ; rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7200" ; rdfs:label "adipose microvascular endothelial cell" ; rdfs:subClassOf obo:CL_0002320, obo:CL_2000008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_2000008 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001013 ] ) ] . obo:CL_2000073 obo:IAO_0000115 "Any migratory neural crest cell that is part of a cardiac neural crest." ; terms:contributor ; oboInOwl:creation_date "2014-11-05T01:18:43Z" ; oboInOwl:hasExactSynonym "cardiac neural crest cell" ; oboInOwl:id "CL:2000073" ; a owl:Class ; rdfs:label "migratory cardiac neural crest cell" ; rdfs:subClassOf obo:CL_0000333, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000095 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000333 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000095 ] ) ] . obo:CL_2000074 obo:IAO_0000115 "Any leukocyte that is part of a spleen." ; terms:contributor ; oboInOwl:creation_date "2014-11-05T01:26:50Z" ; oboInOwl:id "CL:2000074" ; a owl:Class ; rdfs:comment "Splenocytes is a vague term that refers to any one of the different white blood cell types in the spleen. This name is seen many references as such and is not explained further, necessitating a need for this terminology." ; rdfs:label "splenocyte" ; rdfs:subClassOf obo:CL_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000738 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002106 ] ) ] . obo:CL_2000080 obo:IAO_0000115 "Any mesenchymal stem cell of adipose tissue that is part of an abdomen." ; terms:contributor ; oboInOwl:creation_date "2014-12-02T19:10:34Z" ; oboInOwl:hasExactSynonym "mesenchymal stem cell of abdominal adipose" ; oboInOwl:id "CL:2000080" ; a owl:Class ; rdfs:label "mesenchymal stem cell of abdominal adipose tissue" ; rdfs:subClassOf obo:CL_0002570, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000916 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002570 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000916 ] ) ] . obo:CL_2000085 obo:IAO_0000115 "Any mononuclear cell that is part of a umbilical cord." ; terms:contributor ; oboInOwl:creation_date "2014-12-02T20:14:16Z" ; oboInOwl:id "CL:2000085" ; a owl:Class ; rdfs:label "mononuclear cell of umbilical cord" ; rdfs:subClassOf obo:CL_0000349, obo:CL_0000842, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002331 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000842 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002331 ] ) ] . obo:CL_2000091 obo:IAO_0000115 "Any microvascular endothelial cell that is part of a endometrial blood vessel." ; obo:RO_0002175 obo:NCBITaxon_9606 ; terms:contributor ; oboInOwl:creation_date "2015-03-31T21:02:36Z" ; oboInOwl:id "CL:2000091" ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "endometrial microvascular endothelial cell" ; rdfs:subClassOf obo:CL_0009095, obo:CL_2000008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0015172 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_2000008 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0015172 ] ) ] . obo:CL_2000093 obo:IAO_0000115 "Any fibroblast of lung that is part of a bronchus." ; terms:contributor ; oboInOwl:creation_date "2015-03-31T21:16:22Z" ; oboInOwl:id "CL:2000093" ; a owl:Class ; rdfs:label "bronchus fibroblast of lung" ; rdfs:subClassOf obo:CL_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002185 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002553 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002185 ] ) ] . obo:CL_2000095 obo:IAO_0000115 "Any hematopoietic stem cell that is part of a umbilical cord blood." ; terms:contributor ; oboInOwl:creation_date "2015-05-26T18:58:34Z" ; oboInOwl:id "CL:2000095" ; a owl:Class ; rdfs:label "cord blood hematopoietic stem cell" ; rdfs:subClassOf obo:CL_0002246, obo:CL_0002352, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0012168 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000037 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0012168 ] ) ] . obo:CL_2000097 obo:IAO_0000115 "Any dopaminergic neuron that is part of a midbrain." ; terms:contributor ; oboInOwl:creation_date "2015-12-03T16:42:40Z" ; oboInOwl:id "CL:2000097" ; a owl:Class ; rdfs:label "midbrain dopaminergic neuron" ; rdfs:subClassOf obo:CARO_0000000, obo:CL_0000700, obo:CL_2000029, [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0001891 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000700 [ a owl:Restriction ; owl:onProperty obo:RO_0002100 ; owl:someValuesFrom obo:UBERON_0001891 ] ) ] . obo:CL_3000000 obo:IAO_0000115 "A ciliated epithelial cell of the esophagus." ; terms:contributor ; oboInOwl:creation_date "2019-02-09T16:40:30Z" ; oboInOwl:id "CL:3000000" ; a owl:Class ; rdfs:label "ciliated epithelial cell of esophagus" ; rdfs:subClassOf obo:CL_0000067, obo:CL_0002252, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001976 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000067 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001976 ] ) ] . obo:CL_3000004 obo:IAO_0000115 "Peripheral sensory neuron." ; terms:contributor ; oboInOwl:creation_date "2019-02-25T19:34:33Z" ; oboInOwl:id "CL:3000004" ; a owl:Class ; rdfs:label "peripheral sensory neuron" ; rdfs:subClassOf obo:CL_0000101, obo:CL_2000032 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_2000032 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0050906 ] ) ] . obo:CL_4023072 obo:IAO_0000115 "A cell that is part of the brain vasculature." ; terms:contributor ; a owl:Class ; rdfs:label "brain vascular cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0008998 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0008998 ] ) ] . obo:CL_4023079 obo:IAO_0000115 "A GABAergic inhibitory neuron that is derived from the midbrain." ; terms:contributor ; a owl:Class ; rdfs:label "midbrain-derived inhibitory neuron" ; rdfs:subClassOf obo:CL_0000540, obo:UBERON_0004121, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:UBERON_0001891 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:UBERON_0001891 ] ) ] . obo:CL_4023168 obo:IAO_0000115 "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli." ; terms:contributor ; a owl:Class ; rdfs:label "somatosensory neuron" ; rdfs:subClassOf obo:CL_0000540, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003942 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000540 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0003942 ] ) ] . obo:CL_4028001 obo:IAO_0000115 "Any capillary endothelial cell that is part of a lung." ; terms:contributor ; oboInOwl:creation_date "2021-11-23T02:31:40Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "lung capillary endothelial cell" ; a owl:Class ; rdfs:label "pulmonary capillary endothelial cell" ; rdfs:subClassOf obo:CL_0002144, obo:CL_2000016 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002144 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_4030025 obo:IAO_0000115 "A fibroblast that is located in the renal cortical interstitium." ; terms:contributor ; terms:date "2022-07-05T15:50:17Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "kidney cortical fibroblast" ; a owl:Class ; rdfs:comment "Renal cortical fibroblasts have key roles in mediating intercellular communication with neighboring/infiltrating cells and extracellular matrix and maintenance of renal tissue architecture. They additionally have an endocrine function in the production of epoetin." ; rdfs:label "renal cortical fibroblast" ; rdfs:subClassOf obo:CL_1000681, obo:CL_1000692 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000057 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005270 ] ) ] . obo:CL_4030029 obo:IAO_0000115 "A lymphocyte located in blood." ; terms:contributor ; terms:date "2022-11-04T14:40:00Z"^^xsd:dateTime ; oboInOwl:inSubset cl:blood_and_immune_upper_slim ; a owl:Class ; rdfs:label "blood lymphocyte" ; rdfs:subClassOf obo:CL_0000542, obo:CL_2000001 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000542 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000178 ] ) ] . obo:CL_4030031 obo:IAO_0000115 "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes." ; terms:contributor ; terms:date "2022-11-30T14:35:08Z"^^xsd:dateTime ; a owl:Class ; rdfs:label "interstitial cell" ; rdfs:subClassOf obo:CL_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005169 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000003 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005169 ] ) ] . obo:CL_4030034 obo:IAO_0000115 "A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium." ; terms:date "2023-01-25T11:06:01Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "ciliated cell of the respiratory tract" ; a owl:Class ; rdfs:label "respiratory ciliated cell" ; rdfs:subClassOf obo:CL_0000064, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004802 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000064 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004802 ] ) ] . obo:CL_4030040 obo:IAO_0000115 "A ciliated cell of the endometrial epithelium. The cilia of this cell type help move mucus from glandular tissue of the endometrium." ; terms:date "2023-02-09T11:25:14Z"^^xsd:dateTime ; oboInOwl:hasBroadSynonym "ciliated cell of the uterus", "uterine ciliated cell" ; oboInOwl:hasExactSynonym "ciliated cell of the endometrium", "endometrium ciliated epithelial cell" ; a owl:Class ; rdfs:comment "In human samples, the expression of FOXJ1 protein, a regulator for motile cilia with epithelial lineage identity, has been noted." ; rdfs:label "endometrial ciliated epithelial cell" ; rdfs:subClassOf obo:CL_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004811 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000064 obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004811 ] ) ] . obo:CL_4030045 obo:IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y" ; a owl:ObjectProperty ; rdfs:label "lacks_part" . obo:CL_4030046 obo:IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)" ; a owl:ObjectProperty ; rdfs:label "lacks_plasma_membrane_part" . obo:CL_4033005 obo:IAO_0000115 "A(n) serous secreting cell that is part of a(n) bronchus submucosal gland." ; terms:contributor ; a owl:Class ; rdfs:label "serous secreting cell of bronchus submucosal gland" ; rdfs:subClassOf obo:CL_0000152, obo:CL_0019001, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000313 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410043 ] ) ] . obo:CL_4033008 obo:IAO_0000115 "A(n) vein endothelial cell that is part of a(n) respiratory system." ; terms:contributor ; a owl:Class ; rdfs:label "vein endothelial cell of respiratory system" ; rdfs:subClassOf obo:CL_0002543, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001004 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0002543 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001004 ] ) ] . obo:CL_4033017 obo:IAO_0000115 "A smooth muscle cell that is part of a bronchiole." ; terms:contributor , ; terms:date "2023-03-16T09:38:17Z"^^xsd:dateTime ; a owl:Class ; rdfs:label "bronchiolar smooth muscle cell" ; rdfs:subClassOf obo:CL_0019019, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002186 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002186 ] ) ] . obo:CL_4033018 obo:IAO_0000115 "A megakaryocyte that is resident in the lung connective tissue." ; terms:contributor , ; terms:date "2023-03-16T11:31:23Z"^^xsd:dateTime ; oboInOwl:hasRelatedSynonym "lung MKs" ; a owl:Class ; rdfs:label "lung megakaryocyte" ; rdfs:subClassOf obo:CL_0000556 . obo:CL_4033020 obo:IAO_0000115 "A mucus secreting cell that is part of a submucosal gland of the trachea." ; terms:contributor , ; terms:date "2023-03-16T13:03:13Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "tracheal submucosal gland mucous cell" ; a owl:Class ; rdfs:label "mucus secreting cell of trachea gland" ; rdfs:subClassOf obo:CL_0000152, obo:CL_0000319, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005203 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000319 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0005203 ] ) ] . obo:CL_4033022 obo:IAO_0000115 "A mucus secreting cell of a submucosal gland of the bronchus." ; terms:contributor , ; terms:date "2023-03-16T15:12:52Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "bronchial gland mucous cell" ; a owl:Class ; rdfs:label "mucus secreting cell of bronchus submucosal gland" ; rdfs:subClassOf obo:CL_0000152, obo:CL_0000319, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000319 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_8410043 ] ) ] . obo:ENVO_00000447 a owl:Class . obo:ENVO_01000048 a owl:Class . obo:ENVO_01000254 a owl:Class . obo:GOREL_0002003 oboInOwl:hasDbXref "GOREL:0002003" ; oboInOwl:hasOBONamespace "external" ; oboInOwl:id "results_in_distribution_of" ; oboInOwl:shorthand "results_in_distribution_of" ; a owl:ObjectProperty ; rdfs:label "results in distribution of", "results_in_distribution_of" . obo:GOREL_0002004 oboInOwl:hasDbXref "GOREL:0002004" ; oboInOwl:hasOBONamespace "external" ; oboInOwl:id "results_in_fission_of" ; oboInOwl:shorthand "results_in_fission_of" ; a owl:ObjectProperty ; rdfs:label "results in fission of", "results_in_fission_of" ; rdfs:subPropertyOf obo:RO_0000057 . obo:GO_0000002 obo:IAO_0000115 "The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000002" ; a owl:Class ; rdfs:label "mitochondrial genome maintenance" ; rdfs:subClassOf obo:GO_0007005 . obo:GO_0000003 obo:IAO_0000115 "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." ; oboInOwl:hasAlternativeId "GO:0019952", "GO:0050876" ; oboInOwl:hasDbXref "Wikipedia:Reproduction" ; oboInOwl:hasExactSynonym "reproductive physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000003" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "reproduction" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0000011 obo:IAO_0000115 "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton." ; obo:RO_0002161 obo:NCBITaxon_4896 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000011" ; a owl:Class ; rdfs:label "vacuole inheritance" ; rdfs:subClassOf obo:GO_0007033, obo:GO_0048308, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4896 ] ], [ a owl:Restriction ; owl:onProperty obo:GOREL_0002003 ; owl:someValuesFrom obo:GO_0005773 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4896 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048308 [ a owl:Restriction ; owl:onProperty obo:GOREL_0002003 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0000018 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000018" ; a owl:Class ; rdfs:label "regulation of DNA recombination" ; rdfs:subClassOf obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006310 ] ) ] . obo:GO_0000022 obo:IAO_0000115 "The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-04-08T15:06:14Z" ; oboInOwl:hasAlternativeId "GO:1905121" ; oboInOwl:hasExactSynonym "spindle elongation during mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microtubule sliding involved in mitotic spindle elongation" ; oboInOwl:id "GO:0000022" ; a owl:Class ; rdfs:label "mitotic spindle elongation" ; rdfs:subClassOf obo:GO_0051231, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051231 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000070 obo:IAO_0000115 "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." ; oboInOwl:hasAlternativeId "GO:0016359" ; oboInOwl:hasExactSynonym "mitotic chromosome segregation" ; oboInOwl:hasNarrowSynonym "mitotic sister-chromatid adhesion release" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000070" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "mitotic sister chromatid segregation" ; rdfs:subClassOf obo:GO_0000819, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098813 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0000075 obo:IAO_0000115 "A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0031576", "GO:0071779", "GO:0072395", "GO:0072404", "GO:0072407" ; oboInOwl:hasDbXref "Wikipedia:Cell_cycle_checkpoint" ; oboInOwl:hasExactSynonym "cell cycle checkpoint", "signal transduction involved in G2/M transition checkpoint", "signal transduction involved in cell cycle checkpoint" ; oboInOwl:hasNarrowSynonym "G1/S checkpoint", "G1/S transition checkpoint", "G2/M checkpoint", "G2/M transition checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000075" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here." ; rdfs:label "cell cycle checkpoint signaling" ; rdfs:subClassOf obo:GO_0035556, obo:GO_1901988 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0035556 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044770 ] ) ] . obo:GO_0000077 obo:IAO_0000115 "A signal transduction process that contributes to a DNA damage checkpoint." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-12-08T04:18:11Z" ; oboInOwl:hasAlternativeId "GO:0072422" ; oboInOwl:hasDbXref "Wikipedia:DNA_damage_checkpoint", "Wikipedia:Postreplication_checkpoint" ; oboInOwl:hasExactSynonym "DNA damage checkpoint", "signal transduction involved in DNA damage checkpoint" ; oboInOwl:hasNarrowSynonym "DNA damage response, signal transduction resulting in cell cycle arrest" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000077" ; a owl:Class ; rdfs:label "DNA damage checkpoint signaling" ; rdfs:subClassOf obo:GO_0031570, obo:GO_0042770 . obo:GO_0000082 obo:IAO_0000115 "The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000082" ; a owl:Class ; rdfs:label "G1/S transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0044772, obo:GO_0044843 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044843 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000083 obo:IAO_0000115 "Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000083" ; a owl:Class ; rdfs:label "regulation of transcription involved in G1/S transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0006355, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006355 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000082 ] ) ] . obo:GO_0000084 obo:IAO_0000115 "The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle." ; oboInOwl:hasExactSynonym "S phase of mitotic cell cycle", "S-phase of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000084" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "mitotic S phase" ; rdfs:subClassOf obo:GO_0051320, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051329 ] . obo:GO_0000086 obo:IAO_0000115 "The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex." ; oboInOwl:hasExactSynonym "mitotic G2/M transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000086" ; a owl:Class ; rdfs:label "G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0044772, obo:GO_0044839 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044839 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000087 obo:IAO_0000115 "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle." ; oboInOwl:hasExactSynonym "M phase of mitotic cell cycle", "M-phase of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000087" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "mitotic M phase" ; rdfs:subClassOf obo:GO_0000279, obo:GO_0098763 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000279 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000117 obo:IAO_0000115 "Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "G2/M-specific transcription in mitotic cell cycle", "regulation of transcription from RNA polymerase II promoter during G2/M transition of mitotic cell cycle" ; oboInOwl:id "GO:0000117" ; a owl:Class ; rdfs:label "regulation of transcription involved in G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0006355, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000086 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006355 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000086 ] ) ] . obo:GO_0000122 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II." ; oboInOwl:hasAlternativeId "GO:0010553", "GO:0045816" ; oboInOwl:hasExactSynonym "down regulation of transcription from RNA polymerase II promoter", "down-regulation of transcription from RNA polymerase II promoter", "downregulation of transcription from RNA polymerase II promoter", "inhibition of transcription from RNA polymerase II promoter", "negative regulation of transcription from Pol II promoter", "negative regulation of transcription from RNA polymerase II promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of global transcription from RNA polymerase II promoter", "down-regulation of global transcription from RNA polymerase II promoter", "downregulation of global transcription from RNA polymerase II promoter", "inhibition of global transcription from RNA polymerase II promoter", "negative regulation of gene-specific transcription from RNA polymerase II promoter", "negative regulation of global transcription from Pol II promoter", "negative regulation of transcription from RNA polymerase II promoter, global" ; oboInOwl:id "GO:0000122" ; a owl:Class ; rdfs:label "negative regulation of transcription by RNA polymerase II" ; rdfs:subClassOf obo:GO_0006357, obo:GO_0045892, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006366 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006366 ] ) ] . obo:GO_0000132 obo:IAO_0000115 "A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures." ; oboInOwl:hasAlternativeId "GO:0030607", "GO:0030609" ; oboInOwl:hasExactSynonym "establishment of spindle orientation involved in mitotic cell cycle", "mitotic spindle orientation", "orienting of mitotic spindle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "establishment of spindle orientation during mitosis" ; oboInOwl:id "GO:0000132" ; a owl:Class ; rdfs:label "establishment of mitotic spindle orientation" ; rdfs:subClassOf obo:GO_0040001, obo:GO_0051294 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051294 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000139 obo:IAO_0000115 "The lipid bilayer surrounding any of the compartments of the Golgi apparatus." ; oboInOwl:hasExactSynonym "Golgi apparatus membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0000139" ; a owl:Class ; rdfs:label "Golgi membrane" ; rdfs:subClassOf obo:GO_0098588, [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005794 ] ) ] . obo:GO_0000184 obo:IAO_0000115 "The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins." ; oboInOwl:hasDbXref "Wikipedia:Nonsense-mediated_decay", "Wikipedia:Nonsense-mediated_mRNA_decay" ; oboInOwl:hasExactSynonym "mRNA breakdown, nonsense-mediated decay", "mRNA catabolic process, nonsense-mediated", "mRNA catabolism, nonsense-mediated", "mRNA degradation, nonsense-mediated decay", "nonsense-mediated mRNA decay", "nuclear mRNA catabolic process, nonsense-mediated decay" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000184" ; a owl:Class ; rdfs:label "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ; rdfs:subClassOf obo:GO_0000956 . obo:GO_0000212 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle." ; oboInOwl:hasAlternativeId "GO:0043147" ; oboInOwl:hasExactSynonym "meiotic spindle organisation", "spindle organization during meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiotic spindle organization and biogenesis", "meiotic spindle stabilization" ; oboInOwl:id "GO:0000212" ; a owl:Class ; rdfs:label "meiotic spindle organization" ; rdfs:subClassOf obo:GO_0007051, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007051 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0000226 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23114"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/23195"^^xsd:anyURI ; oboInOwl:hasExactSynonym "microtubule cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microtubule cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0000226" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "microtubule cytoskeleton organization" ; rdfs:subClassOf obo:GO_0007010, obo:GO_0007017, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0015630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0015630 ] ) ] . obo:GO_0000228 obo:IAO_0000115 "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." ; oboInOwl:hasNarrowSynonym "nuclear interphase chromosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0000228" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic ; a owl:Class ; rdfs:label "nuclear chromosome" ; rdfs:subClassOf obo:GO_0005694, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031981 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005694 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0000235 obo:IAO_0000115 "Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0000235" ; a owl:Class ; rdfs:label "astral microtubule" ; rdfs:subClassOf obo:GO_0005876, obo:GO_0005881, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005818 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005876 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005818 ] ) ] . obo:GO_0000262 obo:IAO_0000115 "A chromosome found in the mitochondrion of a eukaryotic cell." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1186327184" ; oboInOwl:hasNarrowSynonym "mitochondrial DNA", "mtDNA" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "mitochondrial genome" ; oboInOwl:id "GO:0000262" ; a owl:Class ; rdfs:label "mitochondrial chromosome" ; rdfs:subClassOf obo:GO_0005694, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042645 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005694 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0000271 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ; oboInOwl:hasExactSynonym "glycan biosynthesis", "glycan biosynthetic process", "polysaccharide anabolism", "polysaccharide biosynthesis", "polysaccharide formation", "polysaccharide synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000271" ; a owl:Class ; rdfs:label "polysaccharide biosynthetic process" ; rdfs:subClassOf obo:GO_0005976, obo:GO_0009059, obo:GO_0016051, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18154 ] ) ] . obo:GO_0000272 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ; oboInOwl:hasAlternativeId "GO:0044244" ; oboInOwl:hasExactSynonym "polysaccharide breakdown", "polysaccharide catabolism", "polysaccharide degradation" ; oboInOwl:hasNarrowSynonym "multicellular organismal polysaccharide catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000272" ; a owl:Class ; rdfs:label "polysaccharide catabolic process" ; rdfs:subClassOf obo:GO_0005976, obo:GO_0009057, obo:GO_0016052, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18154 ] ) ] . obo:GO_0000278 obo:IAO_0000115 "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." ; oboInOwl:hasAlternativeId "GO:0007067" ; oboInOwl:hasDbXref "Wikipedia:Mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitosis" ; oboInOwl:id "GO:0000278" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle." ; rdfs:label "mitotic cell cycle" ; rdfs:subClassOf obo:GO_0007049, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0140014 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007049 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0000279 obo:IAO_0000115 "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase." ; oboInOwl:hasDbXref "Wikipedia:M_phase" ; oboInOwl:hasExactSynonym "M-phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000279" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "M phase" ; rdfs:subClassOf obo:GO_0022403 . obo:GO_0000280 obo:IAO_0000115 "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "karyokinesis" ; oboInOwl:id "GO:0000280" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "nuclear division" ; rdfs:subClassOf obo:GO_0048285, [ a owl:Restriction ; owl:onProperty obo:GOREL_0002004 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048285 [ a owl:Restriction ; owl:onProperty obo:GOREL_0002004 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0000281 obo:IAO_0000115 "A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells." ; oboInOwl:hasExactSynonym "cytokinesis after mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000281" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "mitotic cytokinesis" ; rdfs:subClassOf obo:GO_0061640, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061640 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000302 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." ; oboInOwl:hasExactSynonym "response to AOS", "response to ROI", "response to ROS", "response to active oxygen species", "response to reactive oxidative species", "response to reactive oxygen intermediate" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000302" ; a owl:Class ; rdfs:label "response to reactive oxygen species" ; rdfs:subClassOf obo:GO_0006979, obo:GO_1901700 . obo:GO_0000313 obo:IAO_0000115 "A ribosome contained within a subcellular membrane-bounded organelle." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0000313" ; a owl:Class ; rdfs:label "organellar ribosome" ; rdfs:subClassOf obo:GO_0005840, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005840 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0000323 obo:IAO_0000115 "A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0000323" ; a owl:Class ; rdfs:label "lytic vacuole" ; rdfs:subClassOf obo:GO_0005773 . obo:GO_0000374 obo:IAO_0000115 "The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mRNA splicing" ; oboInOwl:id "GO:0000374" ; a owl:Class ; rdfs:comment "Note that Group III introns are known to be found in mRNA of plastids of euglenoid protists." ; rdfs:label "Group III intron splicing" ; rdfs:subClassOf obo:GO_0000377 . obo:GO_0000375 obo:IAO_0000115 "Splicing of RNA via a series of two transesterification reactions." ; oboInOwl:hasAlternativeId "GO:0000385", "GO:0031202" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "RNA splicing factor activity, transesterification mechanism", "pre-mRNA splicing factor activity", "spliceosomal catalysis" ; oboInOwl:id "GO:0000375" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism." ; rdfs:label "RNA splicing, via transesterification reactions" ; rdfs:subClassOf obo:GO_0008380 . obo:GO_0000377 obo:IAO_0000115 "Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lariat RNA biosynthesis", "lariat RNA formation" ; oboInOwl:id "GO:0000377" ; a owl:Class ; rdfs:label "RNA splicing, via transesterification reactions with bulged adenosine as nucleophile" ; rdfs:subClassOf obo:GO_0000375 . obo:GO_0000398 obo:IAO_0000115 "The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." ; oboInOwl:hasAlternativeId "GO:0006374", "GO:0006375" ; oboInOwl:hasBroadSynonym "mRNA splicing", "pre-mRNA splicing" ; oboInOwl:hasExactSynonym "nuclear mRNA splicing, via spliceosome" ; oboInOwl:hasNarrowSynonym "nuclear mRNA splicing via U12-type spliceosome", "nuclear mRNA splicing via U2-type spliceosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "splicing AT-AC intron", "splicing GT-AG intron" ; oboInOwl:id "GO:0000398" ; a owl:Class ; rdfs:comment "Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron." ; rdfs:label "mRNA splicing, via spliceosome" ; rdfs:subClassOf obo:GO_0000377, obo:GO_0006397 . obo:GO_0000422 obo:IAO_0000115 "The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions." ; oboInOwl:hasDbXref "Wikipedia:Autophagy_(cellular)#Selective_autophagy", "Wikipedia:Mitophagy" ; oboInOwl:hasExactSynonym "mitochondrion autophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitophagy" ; oboInOwl:id "GO:0000422" ; a owl:Class ; rdfs:label "autophagy of mitochondrion" ; rdfs:subClassOf obo:GO_0006914, obo:GO_0061726 . obo:GO_0000423 obo:IAO_0000115 "The selective autophagy process in which a mitochondrion is degraded by macroautophagy." ; oboInOwl:hasExactSynonym "macromitophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000423" ; a owl:Class ; rdfs:comment "Note that this terms refers to the macroautophagy process and is named by common usage. Be aware that there are a separate micromitophagy and mitophagy by induced vacuole formation processes." ; rdfs:label "mitophagy" ; rdfs:subClassOf obo:GO_0000422, obo:GO_0061912 . obo:GO_0000578 obo:IAO_0000115 "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "embryonic axis determination" ; oboInOwl:id "GO:0000578" ; a owl:Class ; rdfs:label "embryonic axis specification" ; rdfs:subClassOf obo:GO_0009798, obo:GO_0009880 . obo:GO_0000723 obo:IAO_0000115 "Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of telomere length" ; oboInOwl:id "GO:0000723" ; a owl:Class ; rdfs:label "telomere maintenance" ; rdfs:subClassOf obo:GO_0006259, obo:GO_0032200 . obo:GO_0000740 obo:IAO_0000115 "The joining of 2 or more lipid bilayer membranes that surround the nucleus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000740" ; a owl:Class ; rdfs:label "nuclear membrane fusion" ; rdfs:subClassOf obo:GO_0071763, obo:GO_0090174, [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0031965 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061025 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0031965 ] ) ] . obo:GO_0000741 obo:IAO_0000115 "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei." ; oboInOwl:hasAlternativeId "GO:0007335" ; oboInOwl:hasDbXref "Wikipedia:Karyogamy" ; oboInOwl:hasExactSynonym "nuclear fusion", "nuclear fusion during karyogamy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000741" ; a owl:Class ; rdfs:label "karyogamy" ; rdfs:subClassOf obo:GO_0006997, obo:GO_0048284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006997 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048284 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0000768 obo:IAO_0000115 "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ; oboInOwl:hasBroadSynonym "cell fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000768" ; a owl:Class ; rdfs:label "syncytium formation by plasma membrane fusion" ; rdfs:subClassOf obo:GO_0006949, obo:GO_0140253 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006949 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0045026 ] ) ] . obo:GO_0000781 obo:IAO_0000115 "The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres)." ; oboInOwl:hasAlternativeId "GO:0000784" ; oboInOwl:hasDbXref "SO:0000624" ; oboInOwl:hasNarrowSynonym "nuclear chromosome, telomere", "nuclear chromosome, telomeric region" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "telomere" ; oboInOwl:id "GO:0000781" ; a owl:Class ; rdfs:comment "Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex." ; rdfs:label "chromosome, telomeric region" ; rdfs:subClassOf obo:GO_0098687 . obo:GO_0000785 obo:IAO_0000115 "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome." ; oboInOwl:hasAlternativeId "GO:0000789", "GO:0000790", "GO:0005717" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1615953555" ; oboInOwl:hasNarrowSynonym "cytoplasmic chromatin", "nuclear chromatin" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "chromosome scaffold" ; oboInOwl:id "GO:0000785" ; a owl:Class ; rdfs:comment "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ; rdfs:label "chromatin" ; rdfs:subClassOf obo:GO_0032993, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005694 ] . obo:GO_0000792 obo:IAO_0000115 "A compact and highly condensed form of chromatin that is refractory to transcription." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22355"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0005720", "GO:0035328" ; oboInOwl:hasDbXref "NIF_Subcellular:sao581845896", "Wikipedia:Heterochromatin" ; oboInOwl:hasExactSynonym "transcriptionally inactive chromatin", "transcriptionally silent chromatin" ; oboInOwl:hasNarrowSynonym "nuclear heterochromatin" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0000792" ; a owl:Class ; rdfs:label "heterochromatin" ; rdfs:subClassOf obo:GO_0000785 . obo:GO_0000793 obo:IAO_0000115 "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cytoplasmic mitotic chromosome", "metaphase chromosome", "mitotic chromosome" ; oboInOwl:id "GO:0000793" ; a owl:Class ; rdfs:comment "Note that this term can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes an 'open mitosis' in which the nuclear envelope breaks down during mitosis." ; rdfs:label "condensed chromosome" ; rdfs:subClassOf obo:GO_0005694 . obo:GO_0000794 obo:IAO_0000115 "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "meiotic chromosome", "nuclear mitotic chromosome" ; oboInOwl:id "GO:0000794" ; a owl:Class ; rdfs:comment "Note that this term and its children can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes a 'closed mitosis' in which the nuclear envelope does not break down during mitosis and for gene products that localize to a meiotic chromosome." ; rdfs:label "condensed nuclear chromosome" ; rdfs:subClassOf obo:GO_0000228, obo:GO_0000793 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000793 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0000819 obo:IAO_0000115 "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000819" ; a owl:Class ; rdfs:label "sister chromatid segregation" ; rdfs:subClassOf obo:GO_0051276, obo:GO_0098813 . obo:GO_0000902 obo:IAO_0000115 "The developmental process in which the size or shape of a cell is generated and organized." ; oboInOwl:hasAlternativeId "GO:0007148", "GO:0045790", "GO:0045791" ; oboInOwl:hasExactSynonym "cellular morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000902" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_yeast ; a owl:Class ; rdfs:label "cell morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_0000000 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_0000000 ] ) ] . obo:GO_0000904 obo:IAO_0000115 "The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000904" ; a owl:Class ; rdfs:label "cell morphogenesis involved in differentiation" ; rdfs:subClassOf obo:GO_0000902, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000902 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ] ) ] . obo:GO_0000910 obo:IAO_0000115 "The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells." ; oboInOwl:hasAlternativeId "GO:0007104", "GO:0016288", "GO:0033205" ; oboInOwl:hasDbXref "Wikipedia:Cytokinesis" ; oboInOwl:hasExactSynonym "cell cycle cytokinesis", "cytokinesis involved in cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000910" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_candida, go:goslim_generic, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. When annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'FtsZ-dependent cytokinesis ; GO:0043093' or Cdv-dependent cytokinesis ; GO:0061639. Also, note that cytokinesis does not necessarily result in physical separation and detachment of the two daughter cells from each other." ; rdfs:label "cytokinesis" ; rdfs:subClassOf obo:GO_0022402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051301 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0090148 ] . obo:GO_0000932 obo:IAO_0000115 "A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing." ; oboInOwl:hasDbXref "Wikipedia:P_body" ; oboInOwl:hasExactSynonym "P body", "cytoplasmic mRNA processing body" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cytoplasmic foci" ; oboInOwl:id "GO:0000932" ; a owl:Class ; rdfs:label "P-body" ; rdfs:subClassOf obo:GO_0036464 . obo:GO_0000956 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells." ; oboInOwl:hasExactSynonym "nuclear mRNA breakdown", "nuclear mRNA catabolism", "nuclear mRNA degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000956" ; a owl:Class ; rdfs:label "nuclear-transcribed mRNA catabolic process" ; rdfs:subClassOf obo:GO_0006402 . obo:GO_0000957 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000957" ; a owl:Class ; rdfs:label "mitochondrial RNA catabolic process" ; rdfs:subClassOf obo:GO_0000959, obo:GO_0006401 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006401 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0000958 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000958" ; a owl:Class ; rdfs:label "mitochondrial mRNA catabolic process" ; rdfs:subClassOf obo:GO_0000957, obo:GO_0006402 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006402 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0000959 obo:IAO_0000115 "The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000959" ; a owl:Class ; rdfs:label "mitochondrial RNA metabolic process" ; rdfs:subClassOf obo:GO_0016070, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016070 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0000960 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000960" ; a owl:Class ; rdfs:label "regulation of mitochondrial RNA catabolic process" ; rdfs:subClassOf obo:GO_0031329, obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000957 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000957 ] ) ] . obo:GO_0000961 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000961" ; a owl:Class ; rdfs:label "negative regulation of mitochondrial RNA catabolic process" ; rdfs:subClassOf obo:GO_0000960, obo:GO_1902369, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000957 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000957 ] ) ] . obo:GO_0000962 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000962" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial RNA catabolic process" ; rdfs:subClassOf obo:GO_0000960, obo:GO_0031331, obo:GO_0051254, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000957 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000957 ] ) ] . obo:GO_0000963 obo:IAO_0000115 "The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000963" ; a owl:Class ; rdfs:label "mitochondrial RNA processing" ; rdfs:subClassOf obo:GO_0000959, obo:GO_0006396, obo:GO_0140053 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006396 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0001101 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." ; oboInOwl:hasBroadSynonym "response to acid" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to acid anion", "response to oxoanion" ; oboInOwl:id "GO:0001101" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead." ; rdfs:label "response to acid chemical" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0001501 obo:IAO_0000115 "The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton)." ; oboInOwl:hasExactSynonym "skeletal development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001501" ; a owl:Class ; rdfs:label "skeletal system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001434 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001434 ] ) ] . obo:GO_0001503 obo:IAO_0000115 "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance." ; oboInOwl:hasDbXref "Wikipedia:Ossification" ; oboInOwl:hasExactSynonym "bone biosynthesis", "bone formation", "osteogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001503" ; a owl:Class ; rdfs:comment "Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'." ; rdfs:label "ossification" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001474 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032501 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001474 ] ) ] . obo:GO_0001505 obo:IAO_0000115 "Any process that modulates levels of neurotransmitter." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001505" ; a owl:Class ; rdfs:label "regulation of neurotransmitter levels" ; rdfs:subClassOf obo:GO_0065008 . obo:GO_0001508 obo:IAO_0000115 "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities." ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001508" ; a owl:Class ; rdfs:comment "Action potentials typically propagate across excitable membranes. This class covers both action potentials that propagate and those that fail to do so." ; rdfs:label "action potential" ; rdfs:subClassOf obo:GO_0042391, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4895 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] . obo:GO_0001525 obo:IAO_0000115 "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels." ; oboInOwl:hasDbXref "Wikipedia:Angiogenesis" ; oboInOwl:hasExactSynonym "blood vessel formation from pre-existing blood vessels" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001525" ; a owl:Class ; rdfs:label "angiogenesis" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048514 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001981 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001981 ] ) ] . obo:GO_0001539 obo:IAO_0000115 "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella." ; oboInOwl:hasExactSynonym "ciliary/flagellar motility" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ciliary or bacterial-type flagellar motility" ; oboInOwl:id "GO:0001539" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC." ; rdfs:label "cilium or flagellum-dependent cell motility" ; rdfs:subClassOf obo:GO_0048870 . obo:GO_0001553 obo:IAO_0000115 "The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation." ; oboInOwl:hasDbXref "Wikipedia:Luteal_phase", "Wikipedia:Luteinization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "luteal phase" ; oboInOwl:id "GO:0001553" ; a owl:Class ; rdfs:label "luteinization" ; rdfs:subClassOf obo:GO_0022602, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008585 ] . obo:GO_0001555 obo:IAO_0000115 "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001555" ; a owl:Class ; rdfs:label "oocyte growth" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0048588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048599 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:CL_0000023 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040007 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:CL_0000023 ] ) ] . obo:GO_0001556 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." ; oboInOwl:hasDbXref "Wikipedia:Oocyte_maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001556" ; a owl:Class ; rdfs:label "oocyte maturation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0048469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048599 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000023 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000023 ] ) ] . obo:GO_0001558 obo:IAO_0000115 "Any process that modulates the frequency, rate, extent or direction of cell growth." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001558" ; a owl:Class ; rdfs:label "regulation of cell growth" ; rdfs:subClassOf obo:GO_0040008, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016049 ] ) ] . obo:GO_0001568 obo:IAO_0000115 "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001568" ; a owl:Class ; rdfs:label "blood vessel development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001944 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001981 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001981 ] ) ] . obo:GO_0001569 obo:IAO_0000115 "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system." ; oboInOwl:hasBroadSynonym "patterning of blood vessels" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001569" ; a owl:Class ; rdfs:label "branching involved in blood vessel morphogenesis" ; rdfs:subClassOf obo:GO_0048754, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001525 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048754 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048514 ] ) ] . obo:GO_0001570 obo:IAO_0000115 "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes." ; oboInOwl:hasDbXref "Wikipedia:Vasculogenesis" ; oboInOwl:hasExactSynonym "vascular morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001570" ; a owl:Class ; rdfs:label "vasculogenesis" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048514 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001981 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001981 ] ) ] . obo:GO_0001578 obo:IAO_0000115 "A process that results in a parallel arrangement of microtubules." ; oboInOwl:hasExactSynonym "microtubule bundling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001578" ; a owl:Class ; rdfs:label "microtubule bundle formation" ; rdfs:subClassOf obo:GO_0000226, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:GO_0005874 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:GO_0097427 ] . obo:GO_0001654 obo:IAO_0000115 "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight." ; oboInOwl:hasAlternativeId "GO:0042460" ; oboInOwl:hasDbXref "Wikipedia:Eye_development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001654" ; a owl:Class ; rdfs:label "eye development" ; rdfs:subClassOf obo:GO_0007423, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0150063 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000970 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000970 ] ) ] . obo:GO_0001655 obo:IAO_0000115 "The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22178"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001655" ; a owl:Class ; rdfs:label "urogenital system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0072001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004122 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004122 ] ) ] . obo:GO_0001656 obo:IAO_0000115 "The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001656" ; a owl:Class ; rdfs:label "metanephros development" ; rdfs:subClassOf obo:GO_0001822, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000081 ] ) ] . obo:GO_0001657 obo:IAO_0000115 "The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001657" ; a owl:Class ; rdfs:label "ureteric bud development" ; rdfs:subClassOf obo:GO_0072164, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000084 ] ) ] . obo:GO_0001658 obo:IAO_0000115 "The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." ; oboInOwl:hasExactSynonym "ureteric bud branching" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001658" ; a owl:Class ; rdfs:label "branching involved in ureteric bud morphogenesis" ; rdfs:subClassOf obo:GO_0048754, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001763 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060675 ] ) ] . obo:GO_0001659 obo:IAO_0000115 "A homeostatic process in which an organism modulates its internal body temperature." ; oboInOwl:hasDbXref "Wikipedia:Thermoregulation" ; oboInOwl:hasExactSynonym "thermoregulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001659" ; a owl:Class ; rdfs:label "temperature homeostasis" ; rdfs:subClassOf obo:GO_0048871 . obo:GO_0001666 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." ; oboInOwl:hasExactSynonym "response to hypoxic stress", "response to lowered oxygen tension" ; oboInOwl:hasNarrowSynonym "response to intermittent hypoxia", "response to sustained hypoxia" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001666" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%." ; rdfs:label "response to hypoxia" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0036293 . obo:GO_0001667 obo:IAO_0000115 "Cell migration that is accomplished by extension and retraction of a pseudopodium." ; oboInOwl:hasExactSynonym "ameboid cell migration", "amoeboid cell migration", "amoeboidal cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001667" ; a owl:Class ; rdfs:comment "Note that this term refers to a mode of migration rather than to any particular cell type." ; rdfs:label "ameboidal-type cell migration" ; rdfs:subClassOf obo:GO_0016477 . obo:GO_0001669 obo:IAO_0000115 "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome." ; oboInOwl:hasDbXref "Wikipedia:Acrosome" ; oboInOwl:hasExactSynonym "acrosomal granule", "acrosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0001669" ; a owl:Class ; rdfs:label "acrosomal vesicle" ; rdfs:subClassOf obo:GO_0030141, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000019 ] . obo:GO_0001673 obo:IAO_0000115 "The nucleus of a male germ cell, a reproductive cell in males." ; oboInOwl:hasAlternativeId "GO:0043081" ; oboInOwl:hasExactSynonym "male germ-cell nucleus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0001673" ; a owl:Class ; rdfs:label "male germ cell nucleus" ; rdfs:subClassOf obo:GO_0043073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000015 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005634 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000015 ] ) ] . obo:GO_0001674 obo:IAO_0000115 "The nucleus of the female germ cell, a reproductive cell in females." ; oboInOwl:hasAlternativeId "GO:0043080" ; oboInOwl:hasExactSynonym "female germ-cell nucleus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0001674" ; a owl:Class ; rdfs:label "female germ cell nucleus" ; rdfs:subClassOf obo:GO_0043073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000021 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005634 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000021 ] ) ] . obo:GO_0001675 obo:IAO_0000115 "The formation of the acrosome from the spermatid Golgi." ; oboInOwl:hasExactSynonym "acrosome formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001675" ; a owl:Class ; rdfs:label "acrosome assembly" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0010927, obo:GO_0022412, obo:GO_0033363, obo:GO_0070925, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007286 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0001669 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0001669 ] ) ] . obo:GO_0001677 obo:IAO_0000115 "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." ; oboInOwl:hasExactSynonym "translation initiation ternary complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001677" ; a owl:Class ; rdfs:label "formation of translation initiation ternary complex" ; rdfs:subClassOf obo:GO_0022618, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006413 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0044207 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0044207 ] ) ] . obo:GO_0001678 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of glucose within a cell." ; oboInOwl:hasExactSynonym "cell glucose homeostasis", "cellular glucose homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001678" ; a owl:Class ; rdfs:label "intracellular glucose homeostasis" ; rdfs:subClassOf obo:GO_0042593, obo:GO_0055082 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019725 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_17234 ] ) ] . obo:GO_0001696 obo:IAO_0000115 "The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." ; oboInOwl:hasNarrowSynonym "hydrochloric acid secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001696" ; a owl:Class ; rdfs:label "gastric acid secretion" ; rdfs:subClassOf obo:GO_0022600, obo:GO_0046717 . obo:GO_0001700 obo:IAO_0000115 "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001700" ; a owl:Class ; rdfs:label "embryonic development via the syncytial blastoderm" ; rdfs:subClassOf obo:GO_0009792, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_50557 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_50557 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0001701 obo:IAO_0000115 "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001701" ; a owl:Class ; rdfs:label "in utero embryonic development" ; rdfs:subClassOf obo:GO_0043009, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_32525 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_32525 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0001702 obo:IAO_0000115 "A gastrulation process in which the initial invagination becomes the anus and the mouth forms second." ; oboInOwl:hasAlternativeId "GO:0010003", "GO:0048276" ; oboInOwl:hasExactSynonym "deuterostomic gastrulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001702" ; a owl:Class ; rdfs:label "gastrulation with mouth forming second" ; rdfs:subClassOf obo:GO_0007369, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33511 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33511 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0001704 obo:IAO_0000115 "The formation of the ectoderm, mesoderm and endoderm during gastrulation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001704" ; a owl:Class ; rdfs:label "formation of primary germ layer" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007369 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000923 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000923 ] ) ] . obo:GO_0001705 obo:IAO_0000115 "The formation of ectoderm during gastrulation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001705" ; a owl:Class ; rdfs:label "ectoderm formation" ; rdfs:subClassOf obo:GO_0001704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007398 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000924 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000924 ] ) ] . obo:GO_0001706 obo:IAO_0000115 "The formation of the endoderm during gastrulation." ; oboInOwl:hasNarrowSynonym "endoblast formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001706" ; a owl:Class ; rdfs:label "endoderm formation" ; rdfs:subClassOf obo:GO_0001704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007492 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000925 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000925 ] ) ] . obo:GO_0001707 obo:IAO_0000115 "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001707" ; a owl:Class ; rdfs:label "mesoderm formation" ; rdfs:subClassOf obo:GO_0001704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048332 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000926 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000926 ] ) ] . obo:GO_0001708 obo:IAO_0000115 "The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001708" ; a owl:Class ; rdfs:label "cell fate specification" ; rdfs:subClassOf obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045165 ] . obo:GO_0001743 obo:IAO_0000115 "The initial developmental process that will lead to the formation of an eye." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "optic placode formation" ; oboInOwl:id "GO:0001743" ; a owl:Class ; rdfs:label "lens placode formation" ; rdfs:subClassOf obo:GO_0060788, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048598 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003073 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003073 ] ) ] . obo:GO_0001745 obo:IAO_0000115 "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster." ; oboInOwl:hasExactSynonym "insect-type retina morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001745" ; a owl:Class ; rdfs:label "compound eye morphogenesis" ; rdfs:subClassOf obo:GO_0048592, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048749 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_6656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000018 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_6656 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000018 ] ) ] . obo:GO_0001751 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001751" ; a owl:Class ; rdfs:label "compound eye photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0001754, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001745 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000019 ] ) ] . obo:GO_0001754 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001754" ; a owl:Class ; rdfs:label "eye photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0046530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048592 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000287 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000287 ] ) ] . obo:GO_0001755 obo:IAO_0000115 "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001755" ; a owl:Class ; rdfs:label "neural crest cell migration" ; rdfs:subClassOf obo:GO_0090497, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0014032 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000333 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000333 ] ) ] . obo:GO_0001756 obo:IAO_0000115 "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." ; oboInOwl:hasDbXref "Wikipedia:Somitogenesis" ; oboInOwl:hasExactSynonym "formation of mesodermal clusters" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001756" ; a owl:Class ; rdfs:label "somitogenesis" ; rdfs:subClassOf obo:GO_0009952, obo:GO_0035282, obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043009 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061053 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002329 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002329 ] ) ] . obo:GO_0001763 obo:IAO_0000115 "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes." ; oboInOwl:hasExactSynonym "branching morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001763" ; a owl:Class ; rdfs:label "morphogenesis of a branching structure" ; rdfs:subClassOf obo:GO_0009653, obo:GO_0032501 . obo:GO_0001764 obo:IAO_0000115 "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." ; oboInOwl:hasDbXref "Wikipedia:Neural_development#Neuron_migration", "Wikipedia:Neuron_migration" ; oboInOwl:hasExactSynonym "neuron chemotaxis", "neuronal migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neuron guidance" ; oboInOwl:id "GO:0001764" ; a owl:Class ; rdfs:label "neuron migration" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048699 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000540 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0001767 obo:IAO_0000115 "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell." ; oboInOwl:hasExactSynonym "lymphocyte polarization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001767" ; a owl:Class ; rdfs:label "establishment of lymphocyte polarity" ; rdfs:subClassOf obo:GO_0030010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046649 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000542 ] ) ] . obo:GO_0001768 obo:IAO_0000115 "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell." ; oboInOwl:hasExactSynonym "T cell polarization", "T lymphocyte polarization", "T-cell polarization", "establishment of T lymphocyte polarity", "establishment of T-cell polarity", "establishment of T-lymphocyte polarity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001768" ; a owl:Class ; rdfs:label "establishment of T cell polarity" ; rdfs:subClassOf obo:GO_0001767, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042110 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0001775 obo:IAO_0000115 "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24416"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001775" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cell activation" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0032501 . obo:GO_0001776 obo:IAO_0000115 "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus." ; oboInOwl:hasExactSynonym "immune cell homeostasis", "leucocyte homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001776" ; a owl:Class ; rdfs:comment "Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus." ; rdfs:label "leukocyte homeostasis" ; rdfs:subClassOf obo:GO_0002376, obo:GO_0048872, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000738 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048872 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0001777 obo:IAO_0000115 "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus." ; oboInOwl:hasExactSynonym "T lymphocyte homeostatic proliferation", "T-cell homeostatic proliferation", "T-lymphocyte homeostatic proliferation", "resting T cell proliferation", "resting T-cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001777" ; a owl:Class ; rdfs:label "T cell homeostatic proliferation" ; rdfs:subClassOf obo:GO_0042098, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043029 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042592 ] [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0001816 obo:IAO_0000115 "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19116"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0042032", "GO:0042089", "GO:0042107", "GO:0050663" ; oboInOwl:hasNarrowSynonym "cytokine biosynthetic process", "cytokine metabolic process", "cytokine secretion", "interferon production", "interferon secretion", "interleukin production", "interleukin secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001816" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ; rdfs:label "cytokine production" ; rdfs:subClassOf obo:GO_0010467, obo:GO_0032501 . obo:GO_0001817 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of production of a cytokine." ; oboInOwl:hasAlternativeId "GO:0042035", "GO:0050707" ; oboInOwl:hasExactSynonym "regulation of cytokine anabolism", "regulation of cytokine biosynthesis", "regulation of cytokine formation", "regulation of cytokine synthesis" ; oboInOwl:hasNarrowSynonym "regulation of cytokine biosynthetic process", "regulation of cytokine secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001817" ; a owl:Class ; rdfs:label "regulation of cytokine production" ; rdfs:subClassOf obo:GO_0010468, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001816 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001816 ] ) ] . obo:GO_0001818 obo:IAO_0000115 "Any process that stops, prevents, or reduces the rate of production of a cytokine." ; oboInOwl:hasAlternativeId "GO:0042036", "GO:0050710" ; oboInOwl:hasExactSynonym "down regulation of cytokine biosynthetic process", "down regulation of cytokine production", "down-regulation of cytokine biosynthetic process", "down-regulation of cytokine production", "downregulation of cytokine biosynthetic process", "downregulation of cytokine production", "negative regulation of cytokine anabolism", "negative regulation of cytokine biosynthesis", "negative regulation of cytokine formation", "negative regulation of cytokine synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of cytokine biosynthetic process", "inhibition of cytokine production", "negative regulation of cytokine biosynthetic process", "negative regulation of cytokine secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001818" ; a owl:Class ; rdfs:label "negative regulation of cytokine production" ; rdfs:subClassOf obo:GO_0001817, obo:GO_0010629, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001816 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001816 ] ) ] . obo:GO_0001819 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of production of a cytokine." ; oboInOwl:hasAlternativeId "GO:0042108", "GO:0050715" ; oboInOwl:hasExactSynonym "up regulation of cytokine production", "up-regulation of cytokine production", "upregulation of cytokine production" ; oboInOwl:hasNarrowSynonym "activation of cytokine production", "positive regulation of cytokine biosynthetic process", "positive regulation of cytokine secretion", "stimulation of cytokine production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001819" ; a owl:Class ; rdfs:label "positive regulation of cytokine production" ; rdfs:subClassOf obo:GO_0001817, obo:GO_0010628, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001816 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001816 ] ) ] . obo:GO_0001820 obo:IAO_0000115 "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells." ; oboInOwl:hasExactSynonym "5-HT secretion", "5-hydroxytryptamine secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "serotonin release" ; oboInOwl:id "GO:0001820" ; a owl:Class ; rdfs:label "serotonin secretion" ; rdfs:subClassOf obo:GO_0006837, obo:GO_0023061 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_350546 ] ) ] . obo:GO_0001822 obo:IAO_0000115 "The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine." ; oboInOwl:hasDbXref "Wikipedia:Kidney_development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nephrogenesis" ; oboInOwl:id "GO:0001822" ; a owl:Class ; rdfs:label "kidney development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002113 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002113 ] ) ] . obo:GO_0001823 obo:IAO_0000115 "The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney." ; oboInOwl:hasExactSynonym "Wolffian body development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001823" ; a owl:Class ; rdfs:label "mesonephros development" ; rdfs:subClassOf obo:GO_0001822, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000080 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000080 ] ) ] . obo:GO_0001824 obo:IAO_0000115 "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001824" ; a owl:Class ; rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'." ; rdfs:label "blastocyst development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001701 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_32525 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000358 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_32525 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000358 ] ) ] . obo:GO_0001825 obo:IAO_0000115 "The initial formation of a blastocyst from a solid ball of cells known as a morula." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001825" ; a owl:Class ; rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'." ; rdfs:label "blastocyst formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001824 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000358 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000358 ] ) ] . obo:GO_0001826 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001826" ; a owl:Class ; rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'." ; rdfs:label "inner cell mass cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001825 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000020 ] ) ] . obo:GO_0001829 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell." ; oboInOwl:hasExactSynonym "trophectoderm cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001829" ; a owl:Class ; rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'." ; rdfs:label "trophectodermal cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001825 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000274 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000274 ] ) ] . obo:GO_0001831 obo:IAO_0000115 "The morphogenesis of trophectoderm cells." ; oboInOwl:hasExactSynonym "trophectoderm cellular morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001831" ; a owl:Class ; rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'." ; rdfs:label "trophectodermal cellular morphogenesis" ; rdfs:subClassOf obo:GO_0000904, obo:GO_0048598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001829 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_1000274 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_1000274 ] ) ] . obo:GO_0001832 obo:IAO_0000115 "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001832" ; a owl:Class ; rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'." ; rdfs:label "blastocyst growth" ; rdfs:subClassOf obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001824 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000358 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040007 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000358 ] ) ] . obo:GO_0001833 obo:IAO_0000115 "The proliferation of cells in the inner cell mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001833" ; a owl:Class ; rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'." ; rdfs:label "inner cell mass cell proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001832 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_2000020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_2000020 ] ) ] . obo:GO_0001834 obo:IAO_0000115 "The proliferation of cells in the trophectoderm." ; oboInOwl:hasExactSynonym "trophectoderm cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001834" ; a owl:Class ; rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'." ; rdfs:label "trophectodermal cell proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001832 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_1000274 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_1000274 ] ) ] . obo:GO_0001837 obo:IAO_0000115 "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." ; oboInOwl:hasExactSynonym "EMT", "epithelial-mesenchymal transition", "mesenchymal cell differentiation from epithelial cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001837" ; a owl:Class ; rdfs:label "epithelial to mesenchymal transition" ; rdfs:subClassOf obo:GO_0048762, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000066 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0008019 ] ) ] . obo:GO_0001838 obo:IAO_0000115 "The morphogenesis of an embryonic epithelium into a tube-shaped structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001838" ; a owl:Class ; rdfs:label "embryonic epithelial tube formation" ; rdfs:subClassOf obo:GO_0072175, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016331 ] . obo:GO_0001839 obo:IAO_0000115 "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001839" ; a owl:Class ; rdfs:label "neural plate morphogenesis" ; rdfs:subClassOf obo:GO_0016331, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001840 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003075 ] ) ] . obo:GO_0001840 obo:IAO_0000115 "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001840" ; a owl:Class ; rdfs:label "neural plate development" ; rdfs:subClassOf obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043009 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003075 ] ) ] . obo:GO_0001841 obo:IAO_0000115 "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system." ; oboInOwl:hasAlternativeId "GO:0001679" ; oboInOwl:hasDbXref "Wikipedia:Neurulation" ; oboInOwl:hasExactSynonym "neural tube morphogenesis", "neurulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001841" ; a owl:Class ; rdfs:label "neural tube formation" ; rdfs:subClassOf obo:GO_0001838, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021915 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001049 ] ) ] . obo:GO_0001842 obo:IAO_0000115 "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neural groove formation" ; oboInOwl:id "GO:0001842" ; a owl:Class ; rdfs:label "neural fold formation" ; rdfs:subClassOf obo:GO_0016331, obo:GO_0048646, obo:GO_0060571, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0014020 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005062 ] ) ] . obo:GO_0001878 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001878" ; a owl:Class ; rdfs:comment "defined as response to Saccharomycotina (true yeasts). This excludes fission yeast." ; rdfs:label "response to yeast" ; rdfs:subClassOf obo:GO_0009620, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_147537 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_147537 ] ) ] . obo:GO_0001885 obo:IAO_0000115 "The progression of an endothelial cell over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001885" ; a owl:Class ; rdfs:label "endothelial cell development" ; rdfs:subClassOf obo:GO_0002064, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045446 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000115 ] ) ] . obo:GO_0001886 obo:IAO_0000115 "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001886" ; a owl:Class ; rdfs:label "endothelial cell morphogenesis" ; rdfs:subClassOf obo:GO_0003382, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001885 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_0000115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_0000115 ] ) ] . obo:GO_0001889 obo:IAO_0000115 "The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001889" ; a owl:Class ; rdfs:label "liver development" ; rdfs:subClassOf obo:GO_0048732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061008 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002107 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002107 ] ) ] . obo:GO_0001890 obo:IAO_0000115 "The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." ; oboInOwl:hasExactSynonym "placental development", "placentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001890" ; a owl:Class ; rdfs:label "placenta development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_32525 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001987 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_32525 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001987 ] ) ] . obo:GO_0001892 obo:IAO_0000115 "The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." ; oboInOwl:hasExactSynonym "fetal placenta development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001892" ; a owl:Class ; rdfs:label "embryonic placenta development" ; rdfs:subClassOf obo:GO_0048568, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001701 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001890 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0007106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0007106 ] ) ] . obo:GO_0001893 obo:IAO_0000115 "Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "decidua development" ; oboInOwl:id "GO:0001893" ; a owl:Class ; rdfs:label "maternal placenta development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0048856, obo:GO_0060135, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001890 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002450 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002450 ] ) ] . obo:GO_0001932 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein." ; oboInOwl:hasExactSynonym "regulation of protein amino acid phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001932" ; a owl:Class ; rdfs:label "regulation of protein phosphorylation" ; rdfs:subClassOf obo:GO_0031399, obo:GO_0042325, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006468 ] ) ] . obo:GO_0001933 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein." ; oboInOwl:hasExactSynonym "down regulation of protein amino acid phosphorylation", "down-regulation of protein amino acid phosphorylation", "downregulation of protein amino acid phosphorylation", "negative regulation of protein amino acid phosphorylation" ; oboInOwl:hasNarrowSynonym "inhibition of protein amino acid phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001933" ; a owl:Class ; rdfs:label "negative regulation of protein phosphorylation" ; rdfs:subClassOf obo:GO_0001932, obo:GO_0031400, obo:GO_0042326, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006468 ] ) ] . obo:GO_0001934 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein." ; oboInOwl:hasExactSynonym "positive regulation of protein amino acid phosphorylation", "up regulation of protein amino acid phosphorylation", "up-regulation of protein amino acid phosphorylation", "upregulation of protein amino acid phosphorylation" ; oboInOwl:hasNarrowSynonym "activation of protein amino acid phosphorylation", "stimulation of protein amino acid phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001934" ; a owl:Class ; rdfs:label "positive regulation of protein phosphorylation" ; rdfs:subClassOf obo:GO_0001932, obo:GO_0031401, obo:GO_0042327, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006468 ] ) ] . obo:GO_0001935 obo:IAO_0000115 "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001935" ; a owl:Class ; rdfs:label "endothelial cell proliferation" ; rdfs:subClassOf obo:GO_0050673, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000115 ] ) ] . obo:GO_0001936 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001936" ; a owl:Class ; rdfs:label "regulation of endothelial cell proliferation" ; rdfs:subClassOf obo:GO_0050678, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001935 ] ) ] . obo:GO_0001937 obo:IAO_0000115 "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation." ; oboInOwl:hasExactSynonym "down regulation of endothelial cell proliferation", "down-regulation of endothelial cell proliferation", "downregulation of endothelial cell proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of endothelial cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001937" ; a owl:Class ; rdfs:label "negative regulation of endothelial cell proliferation" ; rdfs:subClassOf obo:GO_0001936, obo:GO_0050680, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001935 ] ) ] . obo:GO_0001938 obo:IAO_0000115 "Any process that activates or increases the rate or extent of endothelial cell proliferation." ; oboInOwl:hasExactSynonym "up regulation of endothelial cell proliferation", "up-regulation of endothelial cell proliferation", "upregulation of endothelial cell proliferation" ; oboInOwl:hasNarrowSynonym "activation of endothelial cell proliferation", "stimulation of endothelial cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001938" ; a owl:Class ; rdfs:label "positive regulation of endothelial cell proliferation" ; rdfs:subClassOf obo:GO_0001936, obo:GO_0050679, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001935 ] ) ] . obo:GO_0001939 obo:IAO_0000115 "The pronucleus originating from the ovum that is being fertilized." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0001939" ; a owl:Class ; rdfs:label "female pronucleus" ; rdfs:subClassOf obo:GO_0045120 . obo:GO_0001940 obo:IAO_0000115 "The pronucleus originating from the spermatozoa that was involved in fertilization." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0001940" ; a owl:Class ; rdfs:label "male pronucleus" ; rdfs:subClassOf obo:GO_0045120 . obo:GO_0001944 obo:IAO_0000115 "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "vascular system development" ; oboInOwl:id "GO:0001944" ; a owl:Class ; rdfs:label "vasculature development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072359 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002049 ] ) ] . obo:GO_0001955 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001955" ; a owl:Class ; rdfs:label "blood vessel maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001568 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001981 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001981 ] ) ] . obo:GO_0001956 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." ; oboInOwl:hasExactSynonym "up regulation of neurotransmitter secretion", "up-regulation of neurotransmitter secretion", "upregulation of neurotransmitter secretion" ; oboInOwl:hasNarrowSynonym "activation of neurotransmitter secretion", "stimulation of neurotransmitter secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001956" ; a owl:Class ; rdfs:label "positive regulation of neurotransmitter secretion" ; rdfs:subClassOf obo:GO_0046928, obo:GO_0050806, obo:GO_0051590, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007269 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007269 ] ) ] . obo:GO_0001957 obo:IAO_0000115 "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells." ; oboInOwl:hasDbXref "Wikipedia:Intramembranous_ossification" ; oboInOwl:hasNarrowSynonym "dermal ossification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intramembranous bone ossification" ; oboInOwl:id "GO:0001957" ; a owl:Class ; rdfs:comment "An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division." ; rdfs:label "intramembranous ossification" ; rdfs:subClassOf obo:GO_0036072 . obo:GO_0001963 obo:IAO_0000115 "The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; oboInOwl:hasExactSynonym "dopaminergic synaptic transmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001963" ; a owl:Class ; rdfs:label "synaptic transmission, dopaminergic" ; rdfs:subClassOf obo:GO_0007268, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:CHEBI_59905 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:CL_0000700 ] . obo:GO_0001966 obo:IAO_0000115 "The directed movement of an animal in response to touch." ; oboInOwl:hasBroadSynonym "taxis in response to mechanical stimulus" ; oboInOwl:hasExactSynonym "stereotaxis", "taxis in response to touch stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001966" ; a owl:Class ; rdfs:label "thigmotaxis" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0002009 obo:IAO_0000115 "The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube." ; oboInOwl:hasExactSynonym "epithelium morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002009" ; a owl:Class ; rdfs:label "morphogenesis of an epithelium" ; rdfs:subClassOf obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060429 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000483 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000483 ] ) ] . obo:GO_0002011 obo:IAO_0000115 "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002011" ; a owl:Class ; rdfs:label "morphogenesis of an epithelial sheet" ; rdfs:subClassOf obo:GO_0002009, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0010136 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0010136 ] ) ] . obo:GO_0002027 obo:IAO_0000115 "Any process that modulates the frequency or rate of heart contraction." ; oboInOwl:hasExactSynonym "cardiac chronotropy", "regulation of heart contraction rate", "regulation of rate of heart contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002027" ; a owl:Class ; rdfs:label "regulation of heart rate" ; rdfs:subClassOf obo:GO_0008016 . obo:GO_0002028 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "regulation of Na+ transport", "regulation of sodium transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002028" ; a owl:Class ; rdfs:label "regulation of sodium ion transport" ; rdfs:subClassOf obo:GO_0010959, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006814 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006814 ] ) ] . obo:GO_0002052 obo:IAO_0000115 "Any process that activates or increases the rate of neuroblast proliferation." ; oboInOwl:hasExactSynonym "up regulation of neuroblast proliferation", "up-regulation of neuroblast proliferation", "upregulation of neuroblast proliferation" ; oboInOwl:hasNarrowSynonym "activation of neuroblast proliferation", "stimulation of neuroblast proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002052" ; a owl:Class ; rdfs:label "positive regulation of neuroblast proliferation" ; rdfs:subClassOf obo:GO_0050769, obo:GO_1902692, obo:GO_2000179, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007405 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007405 ] ) ] . obo:GO_0002053 obo:IAO_0000115 "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells." ; oboInOwl:hasExactSynonym "up regulation of mesenchymal cell proliferation", "up-regulation of mesenchymal cell proliferation", "upregulation of mesenchymal cell proliferation" ; oboInOwl:hasNarrowSynonym "activation of mesenchymal cell proliferation", "stimulation of mesenchymal cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002053" ; a owl:Class ; rdfs:label "positive regulation of mesenchymal cell proliferation" ; rdfs:subClassOf obo:GO_0008284, obo:GO_0010464, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010463 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010463 ] ) ] . obo:GO_0002062 obo:IAO_0000115 "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002062" ; a owl:Class ; rdfs:label "chondrocyte differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051216 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000138 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000138 ] ) ] . obo:GO_0002063 obo:IAO_0000115 "The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002063" ; a owl:Class ; rdfs:label "chondrocyte development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002062 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000138 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000138 ] ) ] . obo:GO_0002064 obo:IAO_0000115 "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002064" ; a owl:Class ; rdfs:label "epithelial cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030855 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000066 ] ) ] . obo:GO_0002065 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002065" ; a owl:Class ; rdfs:label "columnar/cuboidal epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0030855, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000075 ] ) ] . obo:GO_0002066 obo:IAO_0000115 "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002066" ; a owl:Class ; rdfs:label "columnar/cuboidal epithelial cell development" ; rdfs:subClassOf obo:GO_0002064, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002065 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000075 ] ) ] . obo:GO_0002067 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002067" ; a owl:Class ; rdfs:label "glandular epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0002065, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000150 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000150 ] ) ] . obo:GO_0002068 obo:IAO_0000115 "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002068" ; a owl:Class ; rdfs:label "glandular epithelial cell development" ; rdfs:subClassOf obo:GO_0002066, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002067 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000150 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000150 ] ) ] . obo:GO_0002069 obo:IAO_0000115 "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002069" ; a owl:Class ; rdfs:label "columnar/cuboidal epithelial cell maturation" ; rdfs:subClassOf obo:GO_0002070, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002066 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000075 ] ) ] . obo:GO_0002070 obo:IAO_0000115 "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002070" ; a owl:Class ; rdfs:label "epithelial cell maturation" ; rdfs:subClassOf obo:GO_0048469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002064 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000066 ] ) ] . obo:GO_0002071 obo:IAO_0000115 "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002071" ; a owl:Class ; rdfs:label "glandular epithelial cell maturation" ; rdfs:subClassOf obo:GO_0002069, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000150 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000150 ] ) ] . obo:GO_0002072 obo:IAO_0000115 "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus." ; oboInOwl:hasExactSynonym "optic cup morphogenesis involved in camera-style eye development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002072" ; a owl:Class ; rdfs:label "optic cup morphogenesis involved in camera-type eye development" ; rdfs:subClassOf obo:GO_0016331, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060900 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003072 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003072 ] ) ] . obo:GO_0002080 obo:IAO_0000115 "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0002080" ; a owl:Class ; rdfs:label "acrosomal membrane" ; rdfs:subClassOf obo:GO_0030667, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001669 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0001669 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0001669 ] ) ] . obo:GO_0002085 obo:IAO_0000115 "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells." ; oboInOwl:hasNarrowSynonym "negative regulation of neural plate formation", "repression of premature neural plate formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002085" ; a owl:Class ; rdfs:label "inhibition of neuroepithelial cell differentiation" ; rdfs:subClassOf obo:GO_0022603, obo:GO_0030857, obo:GO_0045995, obo:GO_0048505, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060563 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060563 ] ) ] . obo:GO_0002087 obo:IAO_0000115 "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates." ; oboInOwl:hasExactSynonym "neurological control of breathing", "regulation of respiratory gaseous exchange by neurological system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002087" ; a owl:Class ; rdfs:label "regulation of respiratory gaseous exchange by nervous system process" ; rdfs:subClassOf obo:GO_0044065, obo:GO_0050877 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050877 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007585 ] ) ] . obo:GO_0002088 obo:IAO_0000115 "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." ; oboInOwl:hasExactSynonym "lens development", "lens development in camera-style eye" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002088" ; a owl:Class ; rdfs:label "lens development in camera-type eye" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043010 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000965 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000965 ] ) ] . obo:GO_0002089 obo:IAO_0000115 "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus." ; oboInOwl:hasExactSynonym "lens morphogenesis", "lens morphogenesis in camera-style eye" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002089" ; a owl:Class ; rdfs:label "lens morphogenesis in camera-type eye" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002088 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048593 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000965 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000965 ] ) ] . obo:GO_0002119 obo:IAO_0000115 "The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002119" ; a owl:Class ; rdfs:label "nematode larval development" ; rdfs:subClassOf obo:GO_0002164 . obo:GO_0002164 obo:IAO_0000115 "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002164" ; a owl:Class ; rdfs:label "larval development" ; rdfs:subClassOf obo:GO_0007275, obo:GO_0009791 . obo:GO_0002176 obo:IAO_0000115 "The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2010-11-18T02:35:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002176" ; a owl:Class ; rdfs:label "male germ cell proliferation" ; rdfs:subClassOf obo:GO_0036093, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000015 ] ) ] . obo:GO_0002213 obo:IAO_0000115 "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism." ; oboInOwl:hasAlternativeId "GO:0002214" ; oboInOwl:hasExactSynonym "physiological defense response to insect" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002213" ; a owl:Class ; rdfs:label "defense response to insect" ; rdfs:subClassOf obo:GO_0006952, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_50557 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006952 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_50557 ] ) ] . obo:GO_0002215 obo:IAO_0000115 "A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." ; oboInOwl:hasAlternativeId "GO:0002216" ; oboInOwl:hasExactSynonym "physiological defense response to nematode" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002215" ; a owl:Class ; rdfs:label "defense response to nematode" ; rdfs:subClassOf obo:GO_0006952, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_6231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006952 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_6231 ] ) ] . obo:GO_0002227 obo:IAO_0000115 "Any process of the innate immune response that takes place in the mucosal tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002227" ; a owl:Class ; rdfs:label "innate immune response in mucosa" ; rdfs:subClassOf obo:GO_0002385, obo:GO_0045087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0000344 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7711 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7711 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045087 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0000344 ] ) ] . obo:GO_0002232 obo:IAO_0000115 "The movement of an immune cell in response to an external stimulus contributing to an inflammatory response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "immune cell chemotaxis during inflammatory response", "leucocyte chemotaxis during inflammatory response", "leukocyte chemotaxis during inflammatory response" ; oboInOwl:id "GO:0002232" ; a owl:Class ; rdfs:label "leukocyte chemotaxis involved in inflammatory response" ; rdfs:subClassOf obo:GO_0002523, obo:GO_0030595 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030595 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006954 ] ) ] . obo:GO_0002233 obo:IAO_0000115 "The movement of an immune cell in response to an external stimulus a part of an immune response." ; oboInOwl:hasExactSynonym "immune cell chemotaxis during immune response", "leucocyte chemotaxis during immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002233" ; a owl:Class ; rdfs:label "leukocyte chemotaxis involved in immune response" ; rdfs:subClassOf obo:GO_0002522, obo:GO_0030595 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030595 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002244 obo:IAO_0000115 "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells." ; oboInOwl:hasExactSynonym "haematopoietic progenitor cell differentiation", "haemopoietic progenitor cell differentiation", "hemopoietic progenitor cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002244" ; a owl:Class ; rdfs:label "hematopoietic progenitor cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030097 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0008001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0008001 ] ) ] . obo:GO_0002250 obo:IAO_0000115 "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory)." ; oboInOwl:hasDbXref "Wikipedia:Adaptive_immune_system" ; oboInOwl:hasExactSynonym "acquired immune response", "immune memory response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002250" ; a owl:Class ; rdfs:label "adaptive immune response" ; rdfs:subClassOf obo:GO_0006955, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0002251 obo:IAO_0000115 "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues." ; oboInOwl:hasExactSynonym "immune response in organ or tissue" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002251" ; a owl:Class ; rdfs:label "organ or tissue specific immune response" ; rdfs:subClassOf obo:GO_0006955 . obo:GO_0002252 obo:IAO_0000115 "Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/18737"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002252" ; a owl:Class ; rdfs:label "immune effector process" ; rdfs:subClassOf obo:GO_0002376 . obo:GO_0002260 obo:IAO_0000115 "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002260" ; a owl:Class ; rdfs:label "lymphocyte homeostasis" ; rdfs:subClassOf obo:GO_0001776, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048872 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000542 ] ) ] . obo:GO_0002262 obo:IAO_0000115 "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002262" ; a owl:Class ; rdfs:label "myeloid cell homeostasis" ; rdfs:subClassOf obo:GO_0002376, obo:GO_0048872, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000763 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048872 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000763 ] ) ] . obo:GO_0002263 obo:IAO_0000115 "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell activation during immune response" ; oboInOwl:id "GO:0002263" ; a owl:Class ; rdfs:label "cell activation involved in immune response" ; rdfs:subClassOf obo:GO_0001775, obo:GO_0002252, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002264 obo:IAO_0000115 "A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "endothelial cell activation during immune response" ; oboInOwl:id "GO:0002264" ; a owl:Class ; rdfs:label "endothelial cell activation involved in immune response" ; rdfs:subClassOf obo:GO_0002263, obo:GO_0042118 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042118 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002269 obo:IAO_0000115 "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "immune cell activation during inflammatory response", "leukocyte activation during inflammatory response" ; oboInOwl:id "GO:0002269" ; a owl:Class ; rdfs:label "leukocyte activation involved in inflammatory response" ; rdfs:subClassOf obo:GO_0045321, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006954 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045321 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006954 ] ) ] . obo:GO_0002274 obo:IAO_0000115 "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand." ; oboInOwl:hasExactSynonym "myeloid leucocyte activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002274" ; a owl:Class ; rdfs:label "myeloid leukocyte activation" ; rdfs:subClassOf obo:GO_0045321, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000766 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000766 ] ) ] . obo:GO_0002285 obo:IAO_0000115 "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lymphocyte activation during immune response" ; oboInOwl:id "GO:0002285" ; a owl:Class ; rdfs:label "lymphocyte activation involved in immune response" ; rdfs:subClassOf obo:GO_0002366, obo:GO_0046649 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046649 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002286 obo:IAO_0000115 "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "T cell activation during immune response", "T lymphocyte activation during immune response", "T-cell activation during immune response", "T-lymphocyte activation during immune response" ; oboInOwl:id "GO:0002286" ; a owl:Class ; rdfs:label "T cell activation involved in immune response" ; rdfs:subClassOf obo:GO_0002285, obo:GO_0042110 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042110 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002292 obo:IAO_0000115 "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "T cell development involved in immune response", "T cell differentiation during immune response", "T lymphocyte differentiation during immune response", "T-cell differentiation during immune response", "T-lymphocyte differentiation during immune response" ; oboInOwl:id "GO:0002292" ; a owl:Class ; rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "T cell differentiation involved in immune response" ; rdfs:subClassOf obo:GO_0002286, obo:GO_0030217 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030217 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002309 obo:IAO_0000115 "The expansion of a T cell population by cell division as part of an immune response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "T cell proliferation during immune response", "T lymphocyte proliferation during immune response", "T-cell proliferation during immune response", "T-lymphocyte proliferation during immune response" ; oboInOwl:id "GO:0002309" ; a owl:Class ; rdfs:label "T cell proliferation involved in immune response" ; rdfs:subClassOf obo:GO_0002286, obo:GO_0042098 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042098 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002318 obo:IAO_0000115 "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002318" ; a owl:Class ; rdfs:label "myeloid progenitor cell differentiation" ; rdfs:subClassOf obo:GO_0002244, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000839 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000839 ] ) ] . obo:GO_0002320 obo:IAO_0000115 "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002320" ; a owl:Class ; rdfs:label "lymphoid progenitor cell differentiation" ; rdfs:subClassOf obo:GO_0002244, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000838 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000838 ] ) ] . obo:GO_0002351 obo:IAO_0000115 "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." ; oboInOwl:hasBroadSynonym "serotonin production involved in acute inflammatory response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002351" ; a owl:Class ; rdfs:label "serotonin production involved in inflammatory response" ; rdfs:subClassOf obo:GO_0002532 . obo:GO_0002366 obo:IAO_0000115 "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "immune cell activation during immune response", "leucocyte activation during immune response", "leukocyte activation during immune response" ; oboInOwl:id "GO:0002366" ; a owl:Class ; rdfs:label "leukocyte activation involved in immune response" ; rdfs:subClassOf obo:GO_0002263, obo:GO_0045321 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045321 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002367 obo:IAO_0000115 "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels." ; oboInOwl:hasAlternativeId "GO:0002374", "GO:0002375" ; oboInOwl:hasNarrowSynonym "cytokine biosynthetic process involved in immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cytokine production during immune response", "cytokine secretion during immune response", "cytokine secretion involved in immune response" ; oboInOwl:id "GO:0002367" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ; rdfs:label "cytokine production involved in immune response" ; rdfs:subClassOf obo:GO_0001816, obo:GO_0002440, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001816 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002369 obo:IAO_0000115 "Any process that contributes to cytokine production by a T cell." ; oboInOwl:hasExactSynonym "T lymphocyte cytokine production", "T-cell cytokine production", "T-lymphocyte cytokine production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002369" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ; rdfs:label "T cell cytokine production" ; rdfs:subClassOf obo:GO_0002367, obo:GO_0002456 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001816 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0002371 obo:IAO_0000115 "Any process that contributes to cytokine production by a dendritic cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002371" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ; rdfs:label "dendritic cell cytokine production" ; rdfs:subClassOf obo:GO_0002367, obo:GO_0002443, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000451 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001816 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000451 ] ) ] . obo:GO_0002376 obo:IAO_0000115 "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasDbXref "Wikipedia:Immune_system" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002376" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pir ; a owl:Class ; rdfs:comment "Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501)." ; rdfs:label "immune system process" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4895 ] ] ; owl:disjointWith obo:GO_0044848, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] . obo:GO_0002384 obo:IAO_0000115 "An immune response taking place in the liver." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002384" ; a owl:Class ; rdfs:label "hepatic immune response" ; rdfs:subClassOf obo:GO_0002251, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002107 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006955 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002107 ] ) ] . obo:GO_0002385 obo:IAO_0000115 "An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract." ; oboInOwl:hasAlternativeId "GO:0002386", "GO:0002422" ; oboInOwl:hasNarrowSynonym "immune response in MALT", "immune response in mucosal-associated lymphoid tissue", "immune response in urogenital tract" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002385" ; a owl:Class ; rdfs:label "mucosal immune response" ; rdfs:subClassOf obo:GO_0002251 . obo:GO_0002396 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002396" ; a owl:Class ; rdfs:label "MHC protein complex assembly" ; rdfs:subClassOf obo:GO_0065003, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0042611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0042611 ] ) ] . obo:GO_0002399 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002399" ; a owl:Class ; rdfs:label "MHC class II protein complex assembly" ; rdfs:subClassOf obo:GO_0002396, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0042613 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0042613 ] ) ] . obo:GO_0002407 obo:IAO_0000115 "The movement of a dendritic cell in response to an external stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002407" ; a owl:Class ; rdfs:label "dendritic cell chemotaxis" ; rdfs:subClassOf obo:GO_0030595, obo:GO_0036336 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006935 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000451 ] ) ] . obo:GO_0002440 obo:IAO_0000115 "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "production of cellular mediator of immune response" ; oboInOwl:id "GO:0002440" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms." ; rdfs:label "production of molecular mediator of immune response" ; rdfs:subClassOf obo:GO_0002376, obo:GO_0010467 . obo:GO_0002442 obo:IAO_0000115 "The regulated release of serotonin by a cell as part of an inflammatory response." ; oboInOwl:hasBroadSynonym "serotonin secretion involved in acute inflammatory response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "serotonin release involved in inflammatory response" ; oboInOwl:id "GO:0002442" ; a owl:Class ; rdfs:label "serotonin secretion involved in inflammatory response" ; rdfs:subClassOf obo:GO_0001820, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001820 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006954 ] ) ] . obo:GO_0002443 obo:IAO_0000115 "Any process involved in the carrying out of an immune response by a leukocyte." ; oboInOwl:hasAlternativeId "GO:0019723", "GO:0042087" ; oboInOwl:hasExactSynonym "immune cell effector process", "immune cell mediated immunity", "leucocyte immune effector process", "leucocyte mediated immunity", "leukocyte immune effector process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell-mediated immune response", "cellular immune response" ; oboInOwl:id "GO:0002443" ; a owl:Class ; rdfs:label "leukocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002252, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000738 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0002376 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0002444 obo:IAO_0000115 "Any process involved in the carrying out of an immune response by a myeloid leukocyte." ; oboInOwl:hasExactSynonym "myeloid leucocyte immune effector process", "myeloid leucocyte mediated immunity", "myeloid leukocyte immune effector process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002444" ; a owl:Class ; rdfs:label "myeloid leukocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002443, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000766 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0002376 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000766 ] ) ] . obo:GO_0002449 obo:IAO_0000115 "Any process involved in the carrying out of an immune response by a lymphocyte." ; oboInOwl:hasBroadSynonym "cell-mediated immunity", "cellular immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002449" ; a owl:Class ; rdfs:label "lymphocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002443, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0002376 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000542 ] ) ] . obo:GO_0002456 obo:IAO_0000115 "Any process involved in the carrying out of an immune response by a T cell." ; oboInOwl:hasBroadSynonym "cell-mediated immunity", "cellular immune response" ; oboInOwl:hasExactSynonym "T lymphocyte mediated immunity", "T-cell mediated immunity", "T-lymphocyte mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002456" ; a owl:Class ; rdfs:label "T cell mediated immunity" ; rdfs:subClassOf obo:GO_0002449, obo:GO_0002460, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0002376 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0002457 obo:IAO_0000115 "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." ; oboInOwl:hasExactSynonym "T lymphocyte antigen processing and presentation", "T-cell antigen processing and presentation", "T-lymphocyte antigen processing and presentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002457" ; a owl:Class ; rdfs:label "T cell antigen processing and presentation" ; rdfs:subClassOf obo:GO_0019882, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002456 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019882 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0002460 obo:IAO_0000115 "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002460" ; a owl:Class ; rdfs:label "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" ; rdfs:subClassOf obo:GO_0002250 . obo:GO_0002468 obo:IAO_0000115 "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002468" ; a owl:Class ; rdfs:label "dendritic cell antigen processing and presentation" ; rdfs:subClassOf obo:GO_0019882, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000451 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019882 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000451 ] ) ] . obo:GO_0002504 obo:IAO_0000115 "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex." ; oboInOwl:hasExactSynonym "peptide or polysaccharide antigen processing and presentation of via MHC class II" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002504" ; a owl:Class ; rdfs:label "antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ; rdfs:subClassOf obo:GO_0019882 . obo:GO_0002520 obo:IAO_0000115 "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002520" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "immune system development" ; rdfs:subClassOf obo:GO_0002376, obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002405 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002405 ] ) ] . obo:GO_0002521 obo:IAO_0000115 "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ; oboInOwl:hasExactSynonym "immune cell differentiation", "leucocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002521" ; a owl:Class ; rdfs:label "leukocyte differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030097 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000738 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0002522 obo:IAO_0000115 "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response." ; oboInOwl:hasExactSynonym "immune cell migration during immune response", "immune cell trafficking during immune response", "leucocyte migration during immune response", "leucocyte trafficking during immune response", "leukocyte trafficking during immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002522" ; a owl:Class ; rdfs:label "leukocyte migration involved in immune response" ; rdfs:subClassOf obo:GO_0002252, obo:GO_0050900, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050900 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0002523 obo:IAO_0000115 "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "immune cell migration during inflammatory response", "immune cell trafficking during inflammatory response", "leucocyte migration during inflammatory response", "leucocyte trafficking during inflammatory response", "leukocyte migration during inflammatory response", "leukocyte trafficking during inflammatory response" ; oboInOwl:id "GO:0002523" ; a owl:Class ; rdfs:label "leukocyte migration involved in inflammatory response" ; rdfs:subClassOf obo:GO_0050900, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006954 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050900 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006954 ] ) ] . obo:GO_0002532 obo:IAO_0000115 "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels." ; oboInOwl:hasBroadSynonym "production of molecular mediator involved in acute inflammatory response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "production of cellular mediator of acute inflammation" ; oboInOwl:id "GO:0002532" ; a owl:Class ; rdfs:label "production of molecular mediator involved in inflammatory response" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006954 ] . obo:GO_0002534 obo:IAO_0000115 "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels." ; oboInOwl:hasBroadSynonym "cytokine production involved in acute inflammatory response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002534" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "cytokine production involved in inflammatory response" ; rdfs:subClassOf obo:GO_0001816, obo:GO_0002532 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001816 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006954 ] ) ] . obo:GO_0002572 obo:IAO_0000115 "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed." ; oboInOwl:hasExactSynonym "pro-T lymphocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002572" ; a owl:Class ; rdfs:label "pro-T cell differentiation" ; rdfs:subClassOf obo:GO_0002320, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030217 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000827 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000827 ] ) ] . obo:GO_0002573 obo:IAO_0000115 "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage." ; oboInOwl:hasExactSynonym "myeloid leucocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002573" ; a owl:Class ; rdfs:label "myeloid leukocyte differentiation" ; rdfs:subClassOf obo:GO_0002521, obo:GO_0030099, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000766 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000766 ] ) ] . obo:GO_0002577 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of antigen processing and presentation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002577" ; a owl:Class ; rdfs:label "regulation of antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002682, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019882 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019882 ] ) ] . obo:GO_0002578 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation." ; oboInOwl:hasExactSynonym "down regulation of antigen processing and presentation", "down-regulation of antigen processing and presentation", "downregulation of antigen processing and presentation" ; oboInOwl:hasNarrowSynonym "inhibition of antigen processing and presentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002578" ; a owl:Class ; rdfs:label "negative regulation of antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002577, obo:GO_0002683, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019882 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019882 ] ) ] . obo:GO_0002579 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation." ; oboInOwl:hasExactSynonym "up regulation of antigen processing and presentation", "up-regulation of antigen processing and presentation", "upregulation of antigen processing and presentation" ; oboInOwl:hasNarrowSynonym "activation of antigen processing and presentation", "stimulation of antigen processing and presentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002579" ; a owl:Class ; rdfs:label "positive regulation of antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002577, obo:GO_0002684, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019882 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019882 ] ) ] . obo:GO_0002580 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." ; oboInOwl:hasExactSynonym "regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002580" ; a owl:Class ; rdfs:label "regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ; rdfs:subClassOf obo:GO_0002577, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002504 ] ) ] . obo:GO_0002581 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." ; oboInOwl:hasExactSynonym "down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II" ; oboInOwl:hasNarrowSynonym "inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002581" ; a owl:Class ; rdfs:label "negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ; rdfs:subClassOf obo:GO_0002578, obo:GO_0002580, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002504 ] ) ] . obo:GO_0002582 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II." ; oboInOwl:hasExactSynonym "positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II", "up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ; oboInOwl:hasNarrowSynonym "activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II", "stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002582" ; a owl:Class ; rdfs:label "positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II" ; rdfs:subClassOf obo:GO_0002579, obo:GO_0002580, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002504 ] ) ] . obo:GO_0002604 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002604" ; a owl:Class ; rdfs:label "regulation of dendritic cell antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002577, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002468 ] ) ] . obo:GO_0002605 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation." ; oboInOwl:hasExactSynonym "down regulation of dendritic cell antigen processing and presentation", "down-regulation of dendritic cell antigen processing and presentation", "downregulation of dendritic cell antigen processing and presentation" ; oboInOwl:hasNarrowSynonym "inhibition of dendritic cell antigen processing and presentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002605" ; a owl:Class ; rdfs:label "negative regulation of dendritic cell antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002578, obo:GO_0002604, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002468 ] ) ] . obo:GO_0002606 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation." ; oboInOwl:hasExactSynonym "up regulation of dendritic cell antigen processing and presentation", "up-regulation of dendritic cell antigen processing and presentation", "upregulation of dendritic cell antigen processing and presentation" ; oboInOwl:hasNarrowSynonym "activation of dendritic cell antigen processing and presentation", "stimulation of dendritic cell antigen processing and presentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002606" ; a owl:Class ; rdfs:label "positive regulation of dendritic cell antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002579, obo:GO_0002604, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002468 ] ) ] . obo:GO_0002625 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation." ; oboInOwl:hasExactSynonym "regulation of T lymphocyte antigen processing and presentation", "regulation of T-cell antigen processing and presentation", "regulation of T-lymphocyte antigen processing and presentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002625" ; a owl:Class ; rdfs:label "regulation of T cell antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002577, obo:GO_0002709, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002457 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002457 ] ) ] . obo:GO_0002626 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation." ; oboInOwl:hasExactSynonym "down regulation of T cell antigen processing and presentation", "down-regulation of T cell antigen processing and presentation", "downregulation of T cell antigen processing and presentation", "negative regulation of T lymphocyte antigen processing and presentation", "negative regulation of T-cell antigen processing and presentation", "negative regulation of T-lymphocyte antigen processing and presentation" ; oboInOwl:hasNarrowSynonym "inhibition of T cell antigen processing and presentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002626" ; a owl:Class ; rdfs:label "negative regulation of T cell antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002578, obo:GO_0002625, obo:GO_0002710, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002457 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002457 ] ) ] . obo:GO_0002627 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation." ; oboInOwl:hasExactSynonym "positive regulation of T lymphocyte antigen processing and presentation", "positive regulation of T-cell antigen processing and presentation", "positive regulation of T-lymphocyte antigen processing and presentation", "up regulation of T cell antigen processing and presentation", "up-regulation of T cell antigen processing and presentation", "upregulation of T cell antigen processing and presentation" ; oboInOwl:hasNarrowSynonym "activation of T cell antigen processing and presentation", "stimulation of T cell antigen processing and presentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002627" ; a owl:Class ; rdfs:label "positive regulation of T cell antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002579, obo:GO_0002625, obo:GO_0002711, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002457 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002457 ] ) ] . obo:GO_0002682 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of an immune system process." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002682" ; a owl:Class ; rdfs:label "regulation of immune system process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002376 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002376 ] ) ] . obo:GO_0002683 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." ; oboInOwl:hasExactSynonym "down regulation of immune system process", "down-regulation of immune system process", "downregulation of immune system process" ; oboInOwl:hasNarrowSynonym "inhibition of immune system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002683" ; a owl:Class ; rdfs:label "negative regulation of immune system process" ; rdfs:subClassOf obo:GO_0002682, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002376 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002376 ] ) ] . obo:GO_0002684 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of an immune system process." ; oboInOwl:hasExactSynonym "up regulation of immune system process", "up-regulation of immune system process", "upregulation of immune system process" ; oboInOwl:hasNarrowSynonym "activation of immune system process", "stimulation of immune system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002684" ; a owl:Class ; rdfs:label "positive regulation of immune system process" ; rdfs:subClassOf obo:GO_0002682, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002376 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002376 ] ) ] . obo:GO_0002685 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of leukocyte migration." ; oboInOwl:hasExactSynonym "regulation of immune cell migration", "regulation of leucocyte migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002685" ; a owl:Class ; rdfs:label "regulation of leukocyte migration" ; rdfs:subClassOf obo:GO_0002682, obo:GO_0030334, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050900 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050900 ] ) ] . obo:GO_0002686 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration." ; oboInOwl:hasExactSynonym "down regulation of leukocyte migration", "down-regulation of leukocyte migration", "downregulation of leukocyte migration", "negative regulation of immune cell migration", "negative regulation of leucocyte migration" ; oboInOwl:hasNarrowSynonym "inhibition of leukocyte migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002686" ; a owl:Class ; rdfs:label "negative regulation of leukocyte migration" ; rdfs:subClassOf obo:GO_0002683, obo:GO_0002685, obo:GO_0030336, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050900 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050900 ] ) ] . obo:GO_0002687 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of leukocyte migration." ; oboInOwl:hasExactSynonym "positive regulation of immune cell migration", "positive regulation of leucocyte migration", "up regulation of leukocyte migration", "up-regulation of leukocyte migration", "upregulation of leukocyte migration" ; oboInOwl:hasNarrowSynonym "activation of leukocyte migration", "stimulation of leukocyte migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002687" ; a owl:Class ; rdfs:label "positive regulation of leukocyte migration" ; rdfs:subClassOf obo:GO_0002684, obo:GO_0002685, obo:GO_0030335, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050900 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050900 ] ) ] . obo:GO_0002688 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis." ; oboInOwl:hasExactSynonym "regulation of immune cell chemotaxis", "regulation of leucocyte chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002688" ; a owl:Class ; rdfs:label "regulation of leukocyte chemotaxis" ; rdfs:subClassOf obo:GO_0002685, obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030595 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030595 ] ) ] . obo:GO_0002689 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis." ; oboInOwl:hasExactSynonym "down regulation of leukocyte chemotaxis", "down-regulation of leukocyte chemotaxis", "downregulation of leukocyte chemotaxis", "negative regulation of immune cell chemotaxis", "negative regulation of leucocyte chemotaxis" ; oboInOwl:hasNarrowSynonym "inhibition of leukocyte chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002689" ; a owl:Class ; rdfs:label "negative regulation of leukocyte chemotaxis" ; rdfs:subClassOf obo:GO_0002686, obo:GO_0002688, obo:GO_0050922, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030595 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030595 ] ) ] . obo:GO_0002690 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis." ; oboInOwl:hasExactSynonym "positive regulation of immune cell chemotaxis", "positive regulation of leucocyte chemotaxis", "up regulation of leukocyte chemotaxis", "up-regulation of leukocyte chemotaxis", "upregulation of leukocyte chemotaxis" ; oboInOwl:hasNarrowSynonym "activation of leukocyte chemotaxis", "stimulation of leukocyte chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002690" ; a owl:Class ; rdfs:label "positive regulation of leukocyte chemotaxis" ; rdfs:subClassOf obo:GO_0002687, obo:GO_0002688, obo:GO_0050921, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030595 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030595 ] ) ] . obo:GO_0002694 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of leukocyte activation." ; oboInOwl:hasExactSynonym "regulation of immune cell activation", "regulation of leucocyte activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002694" ; a owl:Class ; rdfs:label "regulation of leukocyte activation" ; rdfs:subClassOf obo:GO_0002682, obo:GO_0050865, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045321 ] ) ] . obo:GO_0002695 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation." ; oboInOwl:hasExactSynonym "down regulation of leukocyte activation", "down-regulation of leukocyte activation", "downregulation of leukocyte activation", "negative regulation of immune cell activation", "negative regulation of leucocyte activation" ; oboInOwl:hasNarrowSynonym "inhibition of leukocyte activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002695" ; a owl:Class ; rdfs:label "negative regulation of leukocyte activation" ; rdfs:subClassOf obo:GO_0002683, obo:GO_0002694, obo:GO_0050866, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045321 ] ) ] . obo:GO_0002696 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of leukocyte activation." ; oboInOwl:hasExactSynonym "positive regulation of immune cell activation", "positive regulation of leucocyte activation", "up regulation of leukocyte activation", "up-regulation of leukocyte activation", "upregulation of leukocyte activation" ; oboInOwl:hasNarrowSynonym "activation of leukocyte activation", "stimulation of leukocyte activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002696" ; a owl:Class ; rdfs:label "positive regulation of leukocyte activation" ; rdfs:subClassOf obo:GO_0002684, obo:GO_0002694, obo:GO_0050867, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045321 ] ) ] . obo:GO_0002697 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of an immune effector process." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002697" ; a owl:Class ; rdfs:label "regulation of immune effector process" ; rdfs:subClassOf obo:GO_0002682, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002252 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002252 ] ) ] . obo:GO_0002698 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process." ; oboInOwl:hasExactSynonym "down regulation of immune effector process", "down-regulation of immune effector process", "downregulation of immune effector process" ; oboInOwl:hasNarrowSynonym "inhibition of immune effector process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002698" ; a owl:Class ; rdfs:label "negative regulation of immune effector process" ; rdfs:subClassOf obo:GO_0002683, obo:GO_0002697, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002252 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002252 ] ) ] . obo:GO_0002699 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of an immune effector process." ; oboInOwl:hasExactSynonym "up regulation of immune effector process", "up-regulation of immune effector process", "upregulation of immune effector process" ; oboInOwl:hasNarrowSynonym "activation of immune effector process", "stimulation of immune effector process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002699" ; a owl:Class ; rdfs:label "positive regulation of immune effector process" ; rdfs:subClassOf obo:GO_0002684, obo:GO_0002697, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002252 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002252 ] ) ] . obo:GO_0002700 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002700" ; a owl:Class ; rdfs:label "regulation of production of molecular mediator of immune response" ; rdfs:subClassOf obo:GO_0002697, obo:GO_0010468, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002440 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002440 ] ) ] . obo:GO_0002701 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response." ; oboInOwl:hasExactSynonym "down regulation of production of molecular mediator of immune response", "down-regulation of production of molecular mediator of immune response", "downregulation of production of molecular mediator of immune response" ; oboInOwl:hasNarrowSynonym "inhibition of production of molecular mediator of immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002701" ; a owl:Class ; rdfs:label "negative regulation of production of molecular mediator of immune response" ; rdfs:subClassOf obo:GO_0002698, obo:GO_0002700, obo:GO_0010629, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002440 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002440 ] ) ] . obo:GO_0002702 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response." ; oboInOwl:hasExactSynonym "up regulation of production of molecular mediator of immune response", "up-regulation of production of molecular mediator of immune response", "upregulation of production of molecular mediator of immune response" ; oboInOwl:hasNarrowSynonym "activation of production of molecular mediator of immune response", "stimulation of production of molecular mediator of immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002702" ; a owl:Class ; rdfs:label "positive regulation of production of molecular mediator of immune response" ; rdfs:subClassOf obo:GO_0002699, obo:GO_0002700, obo:GO_0010628, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002440 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002440 ] ) ] . obo:GO_0002703 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity." ; oboInOwl:hasExactSynonym "regulation of immune cell mediated immunity", "regulation of leucocyte mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002703" ; a owl:Class ; rdfs:label "regulation of leukocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002697, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002443 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002443 ] ) ] . obo:GO_0002704 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity." ; oboInOwl:hasExactSynonym "down regulation of leukocyte mediated immunity", "down-regulation of leukocyte mediated immunity", "downregulation of leukocyte mediated immunity", "negative regulation of immune cell mediated immunity", "negative regulation of leucocyte mediated immunity" ; oboInOwl:hasNarrowSynonym "inhibition of leukocyte mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002704" ; a owl:Class ; rdfs:label "negative regulation of leukocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002698, obo:GO_0002703, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002443 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002443 ] ) ] . obo:GO_0002705 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity." ; oboInOwl:hasExactSynonym "positive regulation of immune cell mediated immunity", "positive regulation of leucocyte mediated immunity", "up regulation of leukocyte mediated immunity", "up-regulation of leukocyte mediated immunity", "upregulation of leukocyte mediated immunity" ; oboInOwl:hasNarrowSynonym "activation of leukocyte mediated immunity", "stimulation of leukocyte mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002705" ; a owl:Class ; rdfs:label "positive regulation of leukocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002699, obo:GO_0002703, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002443 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002443 ] ) ] . obo:GO_0002706 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002706" ; a owl:Class ; rdfs:label "regulation of lymphocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002703, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002449 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002449 ] ) ] . obo:GO_0002707 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity." ; oboInOwl:hasExactSynonym "down regulation of lymphocyte mediated immunity", "down-regulation of lymphocyte mediated immunity", "downregulation of lymphocyte mediated immunity" ; oboInOwl:hasNarrowSynonym "inhibition of lymphocyte mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002707" ; a owl:Class ; rdfs:label "negative regulation of lymphocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002704, obo:GO_0002706, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002449 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002449 ] ) ] . obo:GO_0002708 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity." ; oboInOwl:hasExactSynonym "up regulation of lymphocyte mediated immunity", "up-regulation of lymphocyte mediated immunity", "upregulation of lymphocyte mediated immunity" ; oboInOwl:hasNarrowSynonym "activation of lymphocyte mediated immunity", "stimulation of lymphocyte mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002708" ; a owl:Class ; rdfs:label "positive regulation of lymphocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002705, obo:GO_0002706, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002449 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002449 ] ) ] . obo:GO_0002709 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of T cell mediated immunity." ; oboInOwl:hasExactSynonym "regulation of T lymphocyte mediated immunity", "regulation of T-cell mediated immunity", "regulation of T-lymphocyte mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002709" ; a owl:Class ; rdfs:label "regulation of T cell mediated immunity" ; rdfs:subClassOf obo:GO_0002706, obo:GO_0002822, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002456 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002456 ] ) ] . obo:GO_0002710 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity." ; oboInOwl:hasExactSynonym "down regulation of T cell mediated immunity", "down-regulation of T cell mediated immunity", "downregulation of T cell mediated immunity", "negative regulation of T lymphocyte mediated immunity", "negative regulation of T-cell mediated immunity", "negative regulation of T-lymphocyte mediated immunity" ; oboInOwl:hasNarrowSynonym "inhibition of T cell mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002710" ; a owl:Class ; rdfs:label "negative regulation of T cell mediated immunity" ; rdfs:subClassOf obo:GO_0002707, obo:GO_0002709, obo:GO_0002823, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002456 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002456 ] ) ] . obo:GO_0002711 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity." ; oboInOwl:hasExactSynonym "positive regulation of T lymphocyte mediated immunity", "positive regulation of T-cell mediated immunity", "positive regulation of T-lymphocyte mediated immunity", "up regulation of T cell mediated immunity", "up-regulation of T cell mediated immunity", "upregulation of T cell mediated immunity" ; oboInOwl:hasNarrowSynonym "activation of T cell mediated immunity", "stimulation of T cell mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002711" ; a owl:Class ; rdfs:label "positive regulation of T cell mediated immunity" ; rdfs:subClassOf obo:GO_0002708, obo:GO_0002709, obo:GO_0002824, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002456 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002456 ] ) ] . obo:GO_0002718 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response." ; oboInOwl:hasAlternativeId "GO:0002739", "GO:0002742" ; oboInOwl:hasNarrowSynonym "regulation of cytokine biosynthetic process involved in immune response", "regulation of cytokine secretion involved in immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cytokine production during immune response" ; oboInOwl:id "GO:0002718" ; a owl:Class ; rdfs:label "regulation of cytokine production involved in immune response" ; rdfs:subClassOf obo:GO_0001817, obo:GO_0002700, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002367 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002367 ] ) ] . obo:GO_0002719 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response." ; oboInOwl:hasAlternativeId "GO:0002740", "GO:0002743" ; oboInOwl:hasExactSynonym "down-regulation of cytokine production during immune response" ; oboInOwl:hasNarrowSynonym "negative regulation of cytokine biosynthetic process involved in immune response", "negative regulation of cytokine secretion involved in immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of cytokine production during immune response", "downregulation of cytokine production during immune response", "inhibition of cytokine production during immune response", "negative regulation of cytokine production during immune response" ; oboInOwl:id "GO:0002719" ; a owl:Class ; rdfs:label "negative regulation of cytokine production involved in immune response" ; rdfs:subClassOf obo:GO_0001818, obo:GO_0002701, obo:GO_0002718, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002367 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002367 ] ) ] . obo:GO_0002720 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response." ; oboInOwl:hasAlternativeId "GO:0002741", "GO:0002744" ; oboInOwl:hasNarrowSynonym "activation of cytokine production during immune response", "positive regulation of cytokine biosynthetic process involved in immune response", "positive regulation of cytokine secretion involved in immune response", "stimulation of cytokine production during immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cytokine production during immune response", "up regulation of cytokine production during immune response", "up-regulation of cytokine production during immune response", "upregulation of cytokine production during immune response" ; oboInOwl:id "GO:0002720" ; a owl:Class ; rdfs:label "positive regulation of cytokine production involved in immune response" ; rdfs:subClassOf obo:GO_0001819, obo:GO_0002702, obo:GO_0002718, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002367 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002367 ] ) ] . obo:GO_0002724 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of T cell cytokine production." ; oboInOwl:hasExactSynonym "regulation of T lymphocyte cytokine production", "regulation of T-cell cytokine production", "regulation of T-lymphocyte cytokine production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002724" ; a owl:Class ; rdfs:label "regulation of T cell cytokine production" ; rdfs:subClassOf obo:GO_0002709, obo:GO_0002718, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002369 ] ) ] . obo:GO_0002725 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production." ; oboInOwl:hasExactSynonym "down regulation of T cell cytokine production", "down-regulation of T cell cytokine production", "downregulation of T cell cytokine production", "negative regulation of T lymphocyte cytokine production", "negative regulation of T-cell cytokine production", "negative regulation of T-lymphocyte cytokine production" ; oboInOwl:hasNarrowSynonym "inhibition of T cell cytokine production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002725" ; a owl:Class ; rdfs:label "negative regulation of T cell cytokine production" ; rdfs:subClassOf obo:GO_0002710, obo:GO_0002719, obo:GO_0002724, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002369 ] ) ] . obo:GO_0002726 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production." ; oboInOwl:hasExactSynonym "positive regulation of T lymphocyte cytokine production", "positive regulation of T-cell cytokine production", "positive regulation of T-lymphocyte cytokine production", "up regulation of T cell cytokine production", "up-regulation of T cell cytokine production", "upregulation of T cell cytokine production" ; oboInOwl:hasNarrowSynonym "activation of T cell cytokine production", "stimulation of T cell cytokine production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002726" ; a owl:Class ; rdfs:label "positive regulation of T cell cytokine production" ; rdfs:subClassOf obo:GO_0002711, obo:GO_0002720, obo:GO_0002724, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002369 ] ) ] . obo:GO_0002730 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002730" ; a owl:Class ; rdfs:label "regulation of dendritic cell cytokine production" ; rdfs:subClassOf obo:GO_0002703, obo:GO_0002718, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002371 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002371 ] ) ] . obo:GO_0002731 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production." ; oboInOwl:hasExactSynonym "down regulation of dendritic cell cytokine production", "down-regulation of dendritic cell cytokine production", "downregulation of dendritic cell cytokine production" ; oboInOwl:hasNarrowSynonym "inhibition of dendritic cell cytokine production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002731" ; a owl:Class ; rdfs:label "negative regulation of dendritic cell cytokine production" ; rdfs:subClassOf obo:GO_0002704, obo:GO_0002719, obo:GO_0002730, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002371 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002371 ] ) ] . obo:GO_0002732 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production." ; oboInOwl:hasExactSynonym "up regulation of dendritic cell cytokine production", "up-regulation of dendritic cell cytokine production", "upregulation of dendritic cell cytokine production" ; oboInOwl:hasNarrowSynonym "activation of dendritic cell cytokine production", "stimulation of dendritic cell cytokine production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002732" ; a owl:Class ; rdfs:label "positive regulation of dendritic cell cytokine production" ; rdfs:subClassOf obo:GO_0002705, obo:GO_0002720, obo:GO_0002730, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002371 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002371 ] ) ] . obo:GO_0002761 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002761" ; a owl:Class ; rdfs:label "regulation of myeloid leukocyte differentiation" ; rdfs:subClassOf obo:GO_0045637, obo:GO_1902105, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002573 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002573 ] ) ] . obo:GO_0002762 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation." ; oboInOwl:hasExactSynonym "down regulation of myeloid leukocyte differentiation", "down-regulation of myeloid leukocyte differentiation", "downregulation of myeloid leukocyte differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of myeloid leukocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002762" ; a owl:Class ; rdfs:label "negative regulation of myeloid leukocyte differentiation" ; rdfs:subClassOf obo:GO_0002761, obo:GO_0045638, obo:GO_1902106, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002573 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002573 ] ) ] . obo:GO_0002763 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation." ; oboInOwl:hasExactSynonym "up regulation of myeloid leukocyte differentiation", "up-regulation of myeloid leukocyte differentiation", "upregulation of myeloid leukocyte differentiation" ; oboInOwl:hasNarrowSynonym "activation of myeloid leukocyte differentiation", "stimulation of myeloid leukocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002763" ; a owl:Class ; rdfs:label "positive regulation of myeloid leukocyte differentiation" ; rdfs:subClassOf obo:GO_0002761, obo:GO_0045639, obo:GO_1902107, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002573 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002573 ] ) ] . obo:GO_0002790 obo:IAO_0000115 "The controlled release of a peptide from a cell or a tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002790" ; a owl:Class ; rdfs:label "peptide secretion" ; rdfs:subClassOf obo:GO_0015833, obo:GO_0046903 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0002791 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of peptide secretion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002791" ; a owl:Class ; rdfs:label "regulation of peptide secretion" ; rdfs:subClassOf obo:GO_0051046, obo:GO_0090087, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002790 ] ) ] . obo:GO_0002792 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion." ; oboInOwl:hasExactSynonym "down regulation of peptide secretion", "down-regulation of peptide secretion", "downregulation of peptide secretion" ; oboInOwl:hasNarrowSynonym "inhibition of peptide secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002792" ; a owl:Class ; rdfs:label "negative regulation of peptide secretion" ; rdfs:subClassOf obo:GO_0002791, obo:GO_0051048, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002790 ] ) ] . obo:GO_0002793 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of peptide secretion." ; oboInOwl:hasExactSynonym "up regulation of peptide secretion", "up-regulation of peptide secretion", "upregulation of peptide secretion" ; oboInOwl:hasNarrowSynonym "activation of peptide secretion", "stimulation of peptide secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002793" ; a owl:Class ; rdfs:label "positive regulation of peptide secretion" ; rdfs:subClassOf obo:GO_0002791, obo:GO_0051047, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002790 ] ) ] . obo:GO_0002819 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of an adaptive immune response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002819" ; a owl:Class ; rdfs:label "regulation of adaptive immune response" ; rdfs:subClassOf obo:GO_0050776, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002250 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002250 ] ) ] . obo:GO_0002820 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response." ; oboInOwl:hasExactSynonym "down regulation of adaptive immune response", "down-regulation of adaptive immune response", "downregulation of adaptive immune response" ; oboInOwl:hasNarrowSynonym "inhibition of adaptive immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002820" ; a owl:Class ; rdfs:label "negative regulation of adaptive immune response" ; rdfs:subClassOf obo:GO_0002819, obo:GO_0050777, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002250 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002250 ] ) ] . obo:GO_0002821 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response." ; oboInOwl:hasExactSynonym "up regulation of adaptive immune response", "up-regulation of adaptive immune response", "upregulation of adaptive immune response" ; oboInOwl:hasNarrowSynonym "activation of adaptive immune response", "stimulation of adaptive immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002821" ; a owl:Class ; rdfs:label "positive regulation of adaptive immune response" ; rdfs:subClassOf obo:GO_0002819, obo:GO_0050778, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002250 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002250 ] ) ] . obo:GO_0002822 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002822" ; a owl:Class ; rdfs:label "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" ; rdfs:subClassOf obo:GO_0002819, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7776 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002460 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7776 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002460 ] ) ] . obo:GO_0002823 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002823" ; a owl:Class ; rdfs:label "negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" ; rdfs:subClassOf obo:GO_0002820, obo:GO_0002822, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002460 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002460 ] ) ] . obo:GO_0002824 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002824" ; a owl:Class ; rdfs:label "positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" ; rdfs:subClassOf obo:GO_0002821, obo:GO_0002822, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002460 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002460 ] ) ] . obo:GO_0002831 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002831" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "regulation of response to biotic stimulus" ; rdfs:subClassOf obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009607 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009607 ] ) ] . obo:GO_0002832 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to biotic stimulus", "down-regulation of response to biotic stimulus", "downregulation of response to biotic stimulus" ; oboInOwl:hasNarrowSynonym "inhibition of response to biotic stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002832" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "negative regulation of response to biotic stimulus" ; rdfs:subClassOf obo:GO_0002831, obo:GO_0048585, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009607 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009607 ] ) ] . obo:GO_0002833 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to biotic stimulus", "up-regulation of response to biotic stimulus", "upregulation of response to biotic stimulus" ; oboInOwl:hasNarrowSynonym "activation of response to biotic stimulus", "stimulation of response to biotic stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002833" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "positive regulation of response to biotic stimulus" ; rdfs:subClassOf obo:GO_0002831, obo:GO_0048584, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009607 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009607 ] ) ] . obo:GO_0002886 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002886" ; a owl:Class ; rdfs:label "regulation of myeloid leukocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002703, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002444 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002444 ] ) ] . obo:GO_0002887 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity." ; oboInOwl:hasExactSynonym "down regulation of myeloid leukocyte mediated immunity", "down-regulation of myeloid leukocyte mediated immunity", "downregulation of myeloid leukocyte mediated immunity" ; oboInOwl:hasNarrowSynonym "inhibition of myeloid leukocyte mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002887" ; a owl:Class ; rdfs:label "negative regulation of myeloid leukocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002704, obo:GO_0002886, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002444 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002444 ] ) ] . obo:GO_0002888 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity." ; oboInOwl:hasExactSynonym "up regulation of myeloid leukocyte mediated immunity", "up-regulation of myeloid leukocyte mediated immunity", "upregulation of myeloid leukocyte mediated immunity" ; oboInOwl:hasNarrowSynonym "activation of myeloid leukocyte mediated immunity", "stimulation of myeloid leukocyte mediated immunity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002888" ; a owl:Class ; rdfs:label "positive regulation of myeloid leukocyte mediated immunity" ; rdfs:subClassOf obo:GO_0002705, obo:GO_0002886, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002444 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002444 ] ) ] . obo:GO_0002932 obo:IAO_0000115 "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2012-04-23T02:11:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002932" ; a owl:Class ; rdfs:label "tendon sheath development" ; rdfs:subClassOf obo:GO_0061448, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035989 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000304 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000304 ] ) ] . obo:GO_0003002 obo:IAO_0000115 "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pattern formation" ; oboInOwl:id "GO:0003002" ; a owl:Class ; rdfs:label "regionalization" ; rdfs:subClassOf obo:GO_0007389 . obo:GO_0003006 obo:IAO_0000115 "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring." ; oboInOwl:hasNarrowSynonym "puberty" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "reproductive developmental process" ; oboInOwl:id "GO:0003006" ; a owl:Class ; rdfs:label "developmental process involved in reproduction" ; rdfs:subClassOf obo:GO_0022414, obo:GO_0032502 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000003 ] ) ] . obo:GO_0003007 obo:IAO_0000115 "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiac morphogenesis" ; oboInOwl:id "GO:0003007" ; a owl:Class ; rdfs:label "heart morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007100 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007100 ] ) ] . obo:GO_0003008 obo:IAO_0000115 "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." ; oboInOwl:hasExactSynonym "organ system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003008" ; a owl:Class ; rdfs:label "system process" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0003009 obo:IAO_0000115 "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003009" ; a owl:Class ; rdfs:label "skeletal muscle contraction" ; rdfs:subClassOf obo:GO_0006941, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050881 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001134 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006936 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001134 ] ) ] . obo:GO_0003012 obo:IAO_0000115 "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "muscle physiological process" ; oboInOwl:id "GO:0003012" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic ; a owl:Class ; rdfs:label "muscle system process" ; rdfs:subClassOf obo:GO_0003008 . obo:GO_0003013 obo:IAO_0000115 "A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism." ; oboInOwl:hasDbXref "Wikipedia:Circulatory_system" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003013" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic ; a owl:Class ; rdfs:label "circulatory system process" ; rdfs:subClassOf obo:GO_0003008 . obo:GO_0003014 obo:IAO_0000115 "A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila)." ; oboInOwl:hasExactSynonym "excretory system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "kidney system process" ; oboInOwl:id "GO:0003014" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "renal system process" ; rdfs:subClassOf obo:GO_0003008 . obo:GO_0003015 obo:IAO_0000115 "A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiac process" ; oboInOwl:id "GO:0003015" ; a owl:Class ; rdfs:label "heart process" ; rdfs:subClassOf obo:GO_0003013 . obo:GO_0003016 obo:IAO_0000115 "A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange." ; oboInOwl:hasAlternativeId "GO:0010802" ; oboInOwl:hasExactSynonym "respiratory gaseous exchange" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003016" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "respiratory system process" ; rdfs:subClassOf obo:GO_0003008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007585 ] . obo:GO_0003096 obo:IAO_0000115 "The directed movement of sodium ions (Na+) by the renal system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003096" ; a owl:Class ; rdfs:label "renal sodium ion transport" ; rdfs:subClassOf obo:GO_0003014, obo:GO_0006814, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006814 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001008 ] ) ] . obo:GO_0003133 obo:IAO_0000115 "Any process that mediates the transfer of information from endodermal cells to mesodermal cells." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T03:10:29Z" ; oboInOwl:hasExactSynonym "endodermal-mesodermal cell signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003133" ; a owl:Class ; rdfs:label "endodermal-mesodermal cell signaling" ; rdfs:subClassOf obo:GO_0007267, [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:UBERON_0000925 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002232 ; owl:someValuesFrom obo:UBERON_0000926 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:UBERON_0000925 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002232 ; owl:someValuesFrom obo:UBERON_0000926 ] ) ] . obo:GO_0003142 obo:IAO_0000115 "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T04:12:18Z" ; oboInOwl:hasExactSynonym "cardiac crescent morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003142" ; a owl:Class ; rdfs:label "cardiogenic plate morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004139 ] ) ] . obo:GO_0003143 obo:IAO_0000115 "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T04:21:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003143" ; a owl:Class ; rdfs:label "embryonic heart tube morphogenesis" ; rdfs:subClassOf obo:GO_0048598, obo:GO_0060562, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035050 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048562 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004141 ] ) ] . obo:GO_0003144 obo:IAO_0000115 "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T04:22:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003144" ; a owl:Class ; rdfs:label "embryonic heart tube formation" ; rdfs:subClassOf obo:GO_0001838, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003143 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004141 ] ) ] . obo:GO_0003145 obo:IAO_0000115 "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T04:26:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003145" ; a owl:Class ; rdfs:label "embryonic heart tube formation via epithelial folding" ; rdfs:subClassOf obo:GO_0003144 . obo:GO_0003147 obo:IAO_0000115 "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T04:29:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003147" ; a owl:Class ; rdfs:label "neural crest cell migration involved in heart formation" ; rdfs:subClassOf obo:GO_0001755, obo:GO_0060974, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061308 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001755 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060914 ] ) ] . obo:GO_0003148 obo:IAO_0000115 "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T07:51:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003148" ; a owl:Class ; rdfs:label "outflow tract septum morphogenesis" ; rdfs:subClassOf obo:GO_0060411, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003151 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004142 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004142 ] ) ] . obo:GO_0003149 obo:IAO_0000115 "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T07:51:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003149" ; a owl:Class ; rdfs:label "membranous septum morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060412 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004666 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004666 ] ) ] . obo:GO_0003150 obo:IAO_0000115 "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T07:53:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003150" ; a owl:Class ; rdfs:label "muscular septum morphogenesis" ; rdfs:subClassOf obo:GO_0060415, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060412 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004667 ] ) ] . obo:GO_0003151 obo:IAO_0000115 "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-22T07:59:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003151" ; a owl:Class ; rdfs:label "outflow tract morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004145 ] ) ] . obo:GO_0003152 obo:IAO_0000115 "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-23T10:10:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003152" ; a owl:Class ; rdfs:label "morphogenesis of an epithelial fold involved in embryonic heart tube formation" ; rdfs:subClassOf obo:GO_0048598, obo:GO_0060571, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060571 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003144 ] ) ] . obo:GO_0003156 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-30T11:21:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003156" ; a owl:Class ; rdfs:label "regulation of animal organ formation" ; rdfs:subClassOf obo:GO_2000027, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048645 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048645 ] ) ] . obo:GO_0003157 obo:IAO_0000115 "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T12:42:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003157" ; a owl:Class ; rdfs:label "endocardium development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002165 ] ) ] . obo:GO_0003158 obo:IAO_0000115 "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T12:50:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003158" ; a owl:Class ; rdfs:label "endothelium development" ; rdfs:subClassOf obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001986 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001986 ] ) ] . obo:GO_0003159 obo:IAO_0000115 "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T01:34:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003159" ; a owl:Class ; rdfs:label "morphogenesis of an endothelium" ; rdfs:subClassOf obo:GO_0002009, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003158 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001986 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001986 ] ) ] . obo:GO_0003160 obo:IAO_0000115 "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T01:37:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003160" ; a owl:Class ; rdfs:label "endocardium morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003157 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002165 ] ) ] . obo:GO_0003161 obo:IAO_0000115 "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T01:57:16Z" ; oboInOwl:hasExactSynonym "cardiac impulse conducting system development", "heart conduction system development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003161" ; a owl:Class ; rdfs:label "cardiac conduction system development" ; rdfs:subClassOf obo:GO_0048738, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002350 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002350 ] ) ] . obo:GO_0003162 obo:IAO_0000115 "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T02:05:13Z" ; oboInOwl:hasExactSynonym "AV node development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003162" ; a owl:Class ; rdfs:label "atrioventricular node development" ; rdfs:subClassOf obo:GO_0048738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003161 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002352 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002352 ] ) ] . obo:GO_0003163 obo:IAO_0000115 "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T02:06:09Z" ; oboInOwl:hasExactSynonym "SA node development", "SAN development" ; oboInOwl:hasNarrowSynonym "sinus node development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003163" ; a owl:Class ; rdfs:label "sinoatrial node development" ; rdfs:subClassOf obo:GO_0003228, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003161 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002351 ] ) ] . obo:GO_0003164 obo:IAO_0000115 "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T02:07:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003164" ; a owl:Class ; rdfs:label "His-Purkinje system development" ; rdfs:subClassOf obo:GO_0003229, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003161 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004146 ] ) ] . obo:GO_0003165 obo:IAO_0000115 "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T02:07:50Z" ; oboInOwl:hasExactSynonym "cardiac Purkinje fiber development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003165" ; a owl:Class ; rdfs:label "Purkinje myocyte development" ; rdfs:subClassOf obo:GO_0003229, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003164 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002354 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002354 ] ) ] . obo:GO_0003168 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-01T02:49:54Z" ; oboInOwl:hasExactSynonym "cardiac Purkinje fiber cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003168" ; a owl:Class ; rdfs:label "Purkinje myocyte differentiation" ; rdfs:subClassOf obo:GO_0060932, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003165 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002068 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002068 ] ) ] . obo:GO_0003169 obo:IAO_0000115 "The process in which the anatomical structures of veins of the heart are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-08T10:45:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003169" ; a owl:Class ; rdfs:label "coronary vein morphogenesis" ; rdfs:subClassOf obo:GO_0048845, obo:GO_0060977, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004148 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004148 ] ) ] . obo:GO_0003197 obo:IAO_0000115 "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-08T01:17:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003197" ; a owl:Class ; rdfs:label "endocardial cushion development" ; rdfs:subClassOf obo:GO_0060485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002062 ] ) ] . obo:GO_0003203 obo:IAO_0000115 "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-08T01:43:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003203" ; a owl:Class ; rdfs:label "endocardial cushion morphogenesis" ; rdfs:subClassOf obo:GO_0072132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003197 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002062 ] ) ] . obo:GO_0003204 obo:IAO_0000115 "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:05:04Z" ; oboInOwl:hasExactSynonym "heart fibrous skeleton development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003204" ; a owl:Class ; rdfs:label "cardiac skeleton development" ; rdfs:subClassOf obo:GO_0061448, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004292 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004292 ] ) ] . obo:GO_0003205 obo:IAO_0000115 "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:11:18Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003205" ; a owl:Class ; rdfs:label "cardiac chamber development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004151 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004151 ] ) ] . obo:GO_0003206 obo:IAO_0000115 "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:14:51Z" ; oboInOwl:hasExactSynonym "heart chamber morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003206" ; a owl:Class ; rdfs:label "cardiac chamber morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003205 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004151 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004151 ] ) ] . obo:GO_0003207 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:29:13Z" ; oboInOwl:hasExactSynonym "heart chamber formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003207" ; a owl:Class ; rdfs:label "cardiac chamber formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003206 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004151 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004151 ] ) ] . obo:GO_0003208 obo:IAO_0000115 "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:38:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003208" ; a owl:Class ; rdfs:label "cardiac ventricle morphogenesis" ; rdfs:subClassOf obo:GO_0003206, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003231 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002082 ] ) ] . obo:GO_0003209 obo:IAO_0000115 "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:39:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003209" ; a owl:Class ; rdfs:label "cardiac atrium morphogenesis" ; rdfs:subClassOf obo:GO_0003206, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003230 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002081 ] ) ] . obo:GO_0003210 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:44:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003210" ; a owl:Class ; rdfs:label "cardiac atrium formation" ; rdfs:subClassOf obo:GO_0003207, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003209 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002081 ] ) ] . obo:GO_0003211 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:46:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003211" ; a owl:Class ; rdfs:label "cardiac ventricle formation" ; rdfs:subClassOf obo:GO_0003207, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002082 ] ) ] . obo:GO_0003212 obo:IAO_0000115 "The process in which the left cardiac atrium is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:48:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003212" ; a owl:Class ; rdfs:label "cardiac left atrium morphogenesis" ; rdfs:subClassOf obo:GO_0003209, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002079 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002079 ] ) ] . obo:GO_0003213 obo:IAO_0000115 "The process in which the right cardiac atrium is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:49:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003213" ; a owl:Class ; rdfs:label "cardiac right atrium morphogenesis" ; rdfs:subClassOf obo:GO_0003209, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002078 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002078 ] ) ] . obo:GO_0003214 obo:IAO_0000115 "The process in which the left cardiac ventricle is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:50:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003214" ; a owl:Class ; rdfs:label "cardiac left ventricle morphogenesis" ; rdfs:subClassOf obo:GO_0003208, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002084 ] ) ] . obo:GO_0003215 obo:IAO_0000115 "The process in which the right cardiac ventricle is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:50:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003215" ; a owl:Class ; rdfs:label "cardiac right ventricle morphogenesis" ; rdfs:subClassOf obo:GO_0003208, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002080 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002080 ] ) ] . obo:GO_0003216 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:52:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003216" ; a owl:Class ; rdfs:label "cardiac left atrium formation" ; rdfs:subClassOf obo:GO_0003210, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003212 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002079 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002079 ] ) ] . obo:GO_0003217 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:53:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003217" ; a owl:Class ; rdfs:label "cardiac right atrium formation" ; rdfs:subClassOf obo:GO_0003210, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003213 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002078 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002078 ] ) ] . obo:GO_0003218 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:54:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003218" ; a owl:Class ; rdfs:label "cardiac left ventricle formation" ; rdfs:subClassOf obo:GO_0003211, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003214 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002084 ] ) ] . obo:GO_0003219 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T09:55:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003219" ; a owl:Class ; rdfs:label "cardiac right ventricle formation" ; rdfs:subClassOf obo:GO_0003211, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003215 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002080 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002080 ] ) ] . obo:GO_0003220 obo:IAO_0000115 "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T10:18:05Z" ; oboInOwl:hasExactSynonym "left ventricular myocardium morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003220" ; a owl:Class ; rdfs:label "left ventricular cardiac muscle tissue morphogenesis" ; rdfs:subClassOf obo:GO_0055010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003214 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003382 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003382 ] ) ] . obo:GO_0003221 obo:IAO_0000115 "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T10:26:33Z" ; oboInOwl:hasExactSynonym "right ventricle myocardium morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003221" ; a owl:Class ; rdfs:label "right ventricular cardiac muscle tissue morphogenesis" ; rdfs:subClassOf obo:GO_0055010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003215 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003381 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003381 ] ) ] . obo:GO_0003228 obo:IAO_0000115 "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22614"^^xsd:anyURI ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T10:53:18Z" ; oboInOwl:hasExactSynonym "atrial myocardium development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003228" ; a owl:Class ; rdfs:label "atrial cardiac muscle tissue development" ; rdfs:subClassOf obo:GO_0048738, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004490 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004490 ] ) ] . obo:GO_0003229 obo:IAO_0000115 "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T10:56:01Z" ; oboInOwl:hasExactSynonym "ventricular myocardium development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003229" ; a owl:Class ; rdfs:label "ventricular cardiac muscle tissue development" ; rdfs:subClassOf obo:GO_0048738, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0018649 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0018649 ] ) ] . obo:GO_0003230 obo:IAO_0000115 "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:02:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003230" ; a owl:Class ; rdfs:label "cardiac atrium development" ; rdfs:subClassOf obo:GO_0003205, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002081 ] ) ] . obo:GO_0003231 obo:IAO_0000115 "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:03:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003231" ; a owl:Class ; rdfs:label "cardiac ventricle development" ; rdfs:subClassOf obo:GO_0003205, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002082 ] ) ] . obo:GO_0003235 obo:IAO_0000115 "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:12:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003235" ; a owl:Class ; rdfs:label "sinus venosus development" ; rdfs:subClassOf obo:GO_0003205, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002063 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002063 ] ) ] . obo:GO_0003236 obo:IAO_0000115 "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:16:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003236" ; a owl:Class ; rdfs:label "sinus venosus morphogenesis" ; rdfs:subClassOf obo:GO_0003206, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002063 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002063 ] ) ] . obo:GO_0003237 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:18:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003237" ; a owl:Class ; rdfs:label "sinus venosus formation" ; rdfs:subClassOf obo:GO_0003207, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003236 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002063 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002063 ] ) ] . obo:GO_0003238 obo:IAO_0000115 "The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:20:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003238" ; a owl:Class ; rdfs:label "conus arteriosus development" ; rdfs:subClassOf obo:GO_0003205, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003983 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003983 ] ) ] . obo:GO_0003239 obo:IAO_0000115 "The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:25:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003239" ; a owl:Class ; rdfs:label "conus arteriosus morphogenesis" ; rdfs:subClassOf obo:GO_0003206, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003238 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003983 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003983 ] ) ] . obo:GO_0003240 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:25:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003240" ; a owl:Class ; rdfs:label "conus arteriosus formation" ; rdfs:subClassOf obo:GO_0003207, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003239 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003983 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003983 ] ) ] . obo:GO_0003241 obo:IAO_0000115 "Developmental growth that contributes to the shaping of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:28:46Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003241" ; a owl:Class ; rdfs:label "growth involved in heart morphogenesis" ; rdfs:subClassOf obo:GO_0060560, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060419 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ] ) ] . obo:GO_0003245 obo:IAO_0000115 "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:44:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003245" ; a owl:Class ; rdfs:label "cardiac muscle tissue growth involved in heart morphogenesis" ; rdfs:subClassOf obo:GO_0003241, obo:GO_0055017, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055017 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ] ) ] . obo:GO_0003248 obo:IAO_0000115 "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T11:53:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003248" ; a owl:Class ; rdfs:label "heart capillary growth" ; rdfs:subClassOf obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060419 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060976 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0006966 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0006966 ] ) ] . obo:GO_0003253 obo:IAO_0000115 "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-13T02:14:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003253" ; a owl:Class ; rdfs:label "cardiac neural crest cell migration involved in outflow tract morphogenesis" ; rdfs:subClassOf obo:GO_0001755, obo:GO_0060973, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061309 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001755 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003151 ] ) ] . obo:GO_0003260 obo:IAO_0000115 "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-15T01:52:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003260" ; a owl:Class ; rdfs:label "cardioblast migration" ; rdfs:subClassOf obo:GO_0060974, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0002664 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0002664 ] ) ] . obo:GO_0003272 obo:IAO_0000115 "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-20T08:53:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003272" ; a owl:Class ; rdfs:label "endocardial cushion formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003203 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002062 ] ) ] . obo:GO_0003273 obo:IAO_0000115 "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-20T09:08:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003273" ; a owl:Class ; rdfs:label "cell migration involved in endocardial cushion formation" ; rdfs:subClassOf obo:GO_0060973, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003272 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003272 ] ) ] . obo:GO_0003275 obo:IAO_0000115 "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-20T09:30:01Z" ; oboInOwl:hasNarrowSynonym "apoptosis involved in outflow tract morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003275" ; a owl:Class ; rdfs:label "apoptotic process involved in outflow tract morphogenesis" ; rdfs:subClassOf obo:GO_0003278, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003151 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003151 ] ) ] . obo:GO_0003277 obo:IAO_0000115 "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-20T09:37:03Z" ; oboInOwl:hasNarrowSynonym "apoptosis involved in endocardial cushion morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003277" ; a owl:Class ; rdfs:label "apoptotic process involved in endocardial cushion morphogenesis" ; rdfs:subClassOf obo:GO_0003278, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003203 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003203 ] ) ] . obo:GO_0003278 obo:IAO_0000115 "Any apoptotic process that contributes to the shaping of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-20T09:40:22Z" ; oboInOwl:hasNarrowSynonym "apoptosis involved in heart morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003278" ; a owl:Class ; rdfs:label "apoptotic process involved in heart morphogenesis" ; rdfs:subClassOf obo:GO_0060561, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ] ) ] . obo:GO_0003279 obo:IAO_0000115 "The progression of a cardiac septum over time, from its initial formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-20T09:45:13Z" ; oboInOwl:hasExactSynonym "heart septum development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003279" ; a owl:Class ; rdfs:label "cardiac septum development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003205 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002099 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002099 ] ) ] . obo:GO_0003281 obo:IAO_0000115 "The progression of the ventricular septum over time from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-20T10:04:51Z" ; oboInOwl:hasExactSynonym "interventricular septum development" ; oboInOwl:hasNarrowSynonym "septum inferius development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003281" ; a owl:Class ; rdfs:label "ventricular septum development" ; rdfs:subClassOf obo:GO_0003279, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003231 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002094 ] ) ] . obo:GO_0003283 obo:IAO_0000115 "The progression of the atrial septum over time, from its initial formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-20T10:10:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003283" ; a owl:Class ; rdfs:label "atrial septum development" ; rdfs:subClassOf obo:GO_0003279, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003230 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002085 ] ) ] . obo:GO_0003292 obo:IAO_0000115 "The process in which an endocardial cushion cell becomes a cell of a cardiac septum." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-20T11:03:46Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003292" ; a owl:Class ; rdfs:label "cardiac septum cell differentiation" ; rdfs:subClassOf obo:GO_0035051, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003279 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000022 ] ) ] . obo:GO_0003298 obo:IAO_0000115 "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-22T09:24:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003298" ; a owl:Class ; rdfs:label "physiological muscle hypertrophy" ; rdfs:subClassOf obo:GO_0014896 . obo:GO_0003300 obo:IAO_0000115 "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-22T10:33:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003300" ; a owl:Class ; rdfs:label "cardiac muscle hypertrophy" ; rdfs:subClassOf obo:GO_0014897 . obo:GO_0003301 obo:IAO_0000115 "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-22T10:38:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003301" ; a owl:Class ; rdfs:label "physiological cardiac muscle hypertrophy" ; rdfs:subClassOf obo:GO_0003298, obo:GO_0003300, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055017 ] . obo:GO_0003309 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-26T09:27:23Z" ; oboInOwl:hasExactSynonym "pancreatic B cell differentiation", "pancreatic beta cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003309" ; a owl:Class ; rdfs:label "type B pancreatic cell differentiation" ; rdfs:subClassOf obo:GO_0035883, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031018 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000169 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000169 ] ) ] . obo:GO_0003310 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-26T09:28:05Z" ; oboInOwl:hasExactSynonym "pancreatic alpha cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003310" ; a owl:Class ; rdfs:label "pancreatic A cell differentiation" ; rdfs:subClassOf obo:GO_0035883, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031018 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000171 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000171 ] ) ] . obo:GO_0003311 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-26T09:30:27Z" ; oboInOwl:hasExactSynonym "pancreatic delta cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003311" ; a owl:Class ; rdfs:label "pancreatic D cell differentiation" ; rdfs:subClassOf obo:GO_0035883, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031018 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000173 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000173 ] ) ] . obo:GO_0003312 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-26T09:32:32Z" ; oboInOwl:hasExactSynonym "pancreatic polypeptide-producing cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003312" ; a owl:Class ; rdfs:label "pancreatic PP cell differentiation" ; rdfs:subClassOf obo:GO_0035883, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031018 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002275 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002275 ] ) ] . obo:GO_0003313 obo:IAO_0000115 "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-27T08:32:40Z" ; oboInOwl:hasExactSynonym "heart cone development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003313" ; a owl:Class ; rdfs:label "heart rudiment development" ; rdfs:subClassOf obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035050 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004291 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004291 ] ) ] . obo:GO_0003314 obo:IAO_0000115 "The process in which the anatomical structures of the heart rudiment are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-27T08:38:04Z" ; oboInOwl:hasExactSynonym "heart cone morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003314" ; a owl:Class ; rdfs:label "heart rudiment morphogenesis" ; rdfs:subClassOf obo:GO_0002009, obo:GO_0048598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003313 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004291 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004291 ] ) ] . obo:GO_0003315 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the heart rudiment." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-27T08:43:37Z" ; oboInOwl:hasExactSynonym "heart cone formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003315" ; a owl:Class ; rdfs:label "heart rudiment formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003314 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004291 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004291 ] ) ] . obo:GO_0003322 obo:IAO_0000115 "The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-02T08:13:55Z" ; oboInOwl:hasExactSynonym "pancreatic alpha cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003322" ; a owl:Class ; rdfs:label "pancreatic A cell development" ; rdfs:subClassOf obo:GO_0002068, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003310 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000171 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000171 ] ) ] . obo:GO_0003323 obo:IAO_0000115 "The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-02T08:20:11Z" ; oboInOwl:hasExactSynonym "pancreatic B cell development", "pancreatic beta cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003323" ; a owl:Class ; rdfs:label "type B pancreatic cell development" ; rdfs:subClassOf obo:GO_0002068, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003309 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000169 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000169 ] ) ] . obo:GO_0003324 obo:IAO_0000115 "The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-02T08:23:26Z" ; oboInOwl:hasExactSynonym "pancreatic delta cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003324" ; a owl:Class ; rdfs:label "pancreatic D cell development" ; rdfs:subClassOf obo:GO_0002068, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003311 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000173 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000173 ] ) ] . obo:GO_0003325 obo:IAO_0000115 "The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-02T08:25:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003325" ; a owl:Class ; rdfs:label "pancreatic PP cell development" ; rdfs:subClassOf obo:GO_0002068, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003312 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002275 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002275 ] ) ] . obo:GO_0003333 obo:IAO_0000115 "The process in which an amino acid is transported across a membrane." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-02T02:36:11Z" ; oboInOwl:hasExactSynonym "amino acid membrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003333" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "amino acid transmembrane transport" ; rdfs:subClassOf obo:GO_0006865, obo:GO_1903825 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33709 ] ) ] . obo:GO_0003337 obo:IAO_0000115 "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-24T09:29:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "metanephric mesenchyme to epithelial transition" ; oboInOwl:id "GO:0003337" ; a owl:Class ; rdfs:label "mesenchymal to epithelial transition involved in metanephros morphogenesis" ; rdfs:subClassOf obo:GO_0035850, obo:GO_0060231, obo:GO_0072202, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072283 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060231 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003338 ] ) ] . obo:GO_0003338 obo:IAO_0000115 "The process in which the anatomical structures of the metanephros are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-24T09:32:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003338" ; a owl:Class ; rdfs:label "metanephros morphogenesis" ; rdfs:subClassOf obo:GO_0060993, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000081 ] ) ] . obo:GO_0003339 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-24T09:43:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003339" ; a owl:Class ; rdfs:label "regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis" ; rdfs:subClassOf obo:GO_2000696, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003337 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003337 ] ) ] . obo:GO_0003340 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-24T09:46:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003340" ; a owl:Class ; rdfs:label "negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis" ; rdfs:subClassOf obo:GO_0003339, obo:GO_2000697, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003337 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003337 ] ) ] . obo:GO_0003341 obo:IAO_0000115 "The directed, self-propelled movement of a cilium." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI ; obo:RO_0002161 obo:NCBITaxon_3176, obo:NCBITaxon_3312, obo:NCBITaxon_3378, obo:NCBITaxon_3398, obo:NCBITaxon_4890, obo:NCBITaxon_5782 ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-11-24T09:56:26Z" ; oboInOwl:hasAlternativeId "GO:0036142" ; oboInOwl:hasExactSynonym "microtubule-based flagellum movement" ; oboInOwl:hasNarrowSynonym "flagellar movement", "flagellum movement" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ciliary motility", "cilium beating", "flagellar motility" ; oboInOwl:id "GO:0003341" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "cilium movement" ; rdfs:subClassOf obo:GO_0007018, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3176 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3312 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3378 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3398 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4890 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:GO_0005929 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007018 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:GO_0005929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0003342 obo:IAO_0000115 "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-01T10:30:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003342" ; a owl:Class ; rdfs:label "proepicardium development" ; rdfs:subClassOf obo:GO_0060485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003343 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004160 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004160 ] ) ] . obo:GO_0003343 obo:IAO_0000115 "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-01T10:40:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003343" ; a owl:Class ; rdfs:label "septum transversum development" ; rdfs:subClassOf obo:GO_0060485, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004161 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004161 ] ) ] . obo:GO_0003344 obo:IAO_0000115 "The process in which the anatomical structure of the pericardium is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-01T10:46:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003344" ; a owl:Class ; rdfs:label "pericardium morphogenesis" ; rdfs:subClassOf obo:GO_0002011, obo:GO_0048598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060039 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002407 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002407 ] ) ] . obo:GO_0003348 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-01T11:12:05Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003348" ; a owl:Class ; rdfs:label "cardiac endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0035051, obo:GO_0045446, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010008 ] ) ] . obo:GO_0003352 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-03T10:12:00Z" ; oboInOwl:hasAlternativeId "GO:1900172" ; oboInOwl:hasExactSynonym "regulation of microtubule-based flagellum movement" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of flagellar movement", "regulation of flagellum movement" ; oboInOwl:id "GO:0003352" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "regulation of cilium movement" ; rdfs:subClassOf obo:GO_0060632, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003341 ] ) ] . obo:GO_0003353 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-03T10:16:10Z" ; oboInOwl:hasAlternativeId "GO:1900174" ; oboInOwl:hasExactSynonym "positive regulation of microtubule-based flagellum movement" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of flagellar movement", "positive regulation of flagellum movement" ; oboInOwl:id "GO:0003353" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "positive regulation of cilium movement" ; rdfs:subClassOf obo:GO_0003352, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003341 ] ) ] . obo:GO_0003354 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-03T10:17:47Z" ; oboInOwl:hasAlternativeId "GO:1900173" ; oboInOwl:hasExactSynonym "negative regulation of microtubule-based flagellum movement" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of flagellum movement" ; oboInOwl:id "GO:0003354" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "negative regulation of cilium movement" ; rdfs:subClassOf obo:GO_0003352, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003341 ] ) ] . obo:GO_0003357 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-03T10:34:30Z" ; oboInOwl:hasExactSynonym "norepinephrine secreting neuron differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003357" ; a owl:Class ; rdfs:label "noradrenergic neuron differentiation" ; rdfs:subClassOf obo:GO_0030182, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0008025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0008025 ] ) ] . obo:GO_0003358 obo:IAO_0000115 "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-03T10:38:37Z" ; oboInOwl:hasExactSynonym "norepinephrine secreting neuron development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003358" ; a owl:Class ; rdfs:label "noradrenergic neuron development" ; rdfs:subClassOf obo:GO_0048666, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0008025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0008025 ] ) ] . obo:GO_0003360 obo:IAO_0000115 "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-03T10:47:20Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003360" ; a owl:Class ; rdfs:label "brainstem development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002298 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002298 ] ) ] . obo:GO_0003361 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-03T10:53:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003361" ; a owl:Class ; rdfs:label "noradrenergic neuron differentiation involved in brainstem development" ; rdfs:subClassOf obo:GO_0003357, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003360 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0003357 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003360 ] ) ] . obo:GO_0003365 obo:IAO_0000115 "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-08T04:50:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003365" ; a owl:Class ; rdfs:label "establishment of cell polarity involved in ameboidal cell migration" ; rdfs:subClassOf obo:GO_0030010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001667 ] ) ] . obo:GO_0003371 obo:IAO_0000115 "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-08T05:42:46Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003371" ; a owl:Class ; rdfs:label "establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration" ; rdfs:subClassOf obo:GO_0030952, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030952 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001667 ] ) ] . obo:GO_0003379 obo:IAO_0000115 "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-09T06:54:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003379" ; a owl:Class ; rdfs:label "establishment of cell polarity involved in gastrulation cell migration" ; rdfs:subClassOf obo:GO_0003365, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042074 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042074 ] ) ] . obo:GO_0003380 obo:IAO_0000115 "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-09T07:10:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003380" ; a owl:Class ; rdfs:label "establishment or maintenance of cytoskeleton polarity involved in gastrulation" ; rdfs:subClassOf obo:GO_0003371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003379 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030952 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007369 ] ) ] . obo:GO_0003381 obo:IAO_0000115 "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-09T07:18:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003381" ; a owl:Class ; rdfs:label "epithelial cell morphogenesis involved in gastrulation" ; rdfs:subClassOf obo:GO_0003382, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0003382 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007369 ] ) ] . obo:GO_0003382 obo:IAO_0000115 "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-09T07:21:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003382" ; a owl:Class ; rdfs:label "epithelial cell morphogenesis" ; rdfs:subClassOf obo:GO_0000904, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002064 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000066 ] ) ] . obo:GO_0003403 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-21T01:42:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003403" ; a owl:Class ; rdfs:label "optic vesicle formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003404 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060900 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004128 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004128 ] ) ] . obo:GO_0003404 obo:IAO_0000115 "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-21T01:54:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003404" ; a owl:Class ; rdfs:label "optic vesicle morphogenesis" ; rdfs:subClassOf obo:GO_0048598, obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048596 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004128 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004128 ] ) ] . obo:GO_0003407 obo:IAO_0000115 "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-21T02:15:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003407" ; a owl:Class ; rdfs:label "neural retina development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060041 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003902 ] ) ] . obo:GO_0003411 obo:IAO_0000115 "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-21T03:04:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003411" ; a owl:Class ; rdfs:label "cell motility involved in camera-type eye morphogenesis" ; rdfs:subClassOf obo:GO_0048870, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048593 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048870 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048593 ] ) ] . obo:GO_0003413 obo:IAO_0000115 "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-22T08:39:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003413" ; a owl:Class ; rdfs:label "chondrocyte differentiation involved in endochondral bone morphogenesis" ; rdfs:subClassOf obo:GO_0002062, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0002062 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060350 ] ) ] . obo:GO_0003414 obo:IAO_0000115 "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-22T08:42:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003414" ; a owl:Class ; rdfs:label "chondrocyte morphogenesis involved in endochondral bone morphogenesis" ; rdfs:subClassOf obo:GO_0090171, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003433 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0090171 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060350 ] ) ] . obo:GO_0003416 obo:IAO_0000115 "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-22T08:52:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003416" ; a owl:Class ; rdfs:label "endochondral bone growth" ; rdfs:subClassOf obo:GO_0098868, [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0002513 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0002513 ] ) ] . obo:GO_0003433 obo:IAO_0000115 "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-22T12:42:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003433" ; a owl:Class ; rdfs:label "chondrocyte development involved in endochondral bone morphogenesis" ; rdfs:subClassOf obo:GO_0002063, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003413 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0002063 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060350 ] ) ] . obo:GO_0003674 obo:IAO_0000115 "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.", "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process." ; oboInOwl:hasAlternativeId "GO:0005554" ; oboInOwl:hasExactSynonym "molecular function" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0003674" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex." ; rdfs:label "molecular_function" ; rdfs:subClassOf obo:BFO_0000015 ; owl:disjointWith obo:GO_0005575, obo:GO_0008150 . obo:GO_0003676 obo:IAO_0000115 "Binding to a nucleic acid." ; oboInOwl:hasAlternativeId "GO:0000496" ; oboInOwl:hasNarrowSynonym "base pairing" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0003676" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "nucleic acid binding" ; rdfs:subClassOf obo:GO_0097159, obo:GO_1901363, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33696 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33696 ] ) ] . obo:GO_0003677 obo:IAO_0000115 "Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid)." ; oboInOwl:hasAlternativeId "GO:0043566" ; oboInOwl:hasNarrowSynonym "plasmid binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "microtubule/chromatin interaction", "structure specific DNA binding", "structure-specific DNA binding" ; oboInOwl:id "GO:0003677" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "DNA binding" ; rdfs:subClassOf obo:GO_0003676, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16991 ] ) ] . obo:GO_0003682 obo:IAO_0000115 "Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." ; oboInOwl:hasNarrowSynonym "lamin/chromatin binding", "microtubule/chromatin interaction", "nuclear membrane vesicle binding to chromatin" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0003682" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "chromatin binding" ; rdfs:subClassOf obo:GO_0044877, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0000785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0000785 ] ) ] . obo:GO_0003723 obo:IAO_0000115 "Binding to an RNA molecule or a portion thereof." ; oboInOwl:hasAlternativeId "GO:0000498", "GO:0044822" ; oboInOwl:hasDbXref "Reactome:R-HSA-203922" ; oboInOwl:hasNarrowSynonym "base pairing with RNA" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "poly(A) RNA binding", "poly(A)-RNA binding", "poly-A RNA binding" ; oboInOwl:id "GO:0003723" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "RNA binding" ; rdfs:subClassOf obo:GO_0003676, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33697 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33697 ] ) ] . obo:GO_0003824 obo:IAO_0000115 "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." ; oboInOwl:hasDbXref "Wikipedia:Enzyme" ; oboInOwl:hasExactSynonym "enzyme activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0003824" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "catalytic activity" ; rdfs:subClassOf obo:GO_0003674 . obo:GO_0003990 obo:IAO_0000115 "Catalysis of the reaction: acetylcholine + H2O = choline + acetate." ; oboInOwl:hasDbXref "EC:3.1.1.7", "MetaCyc:ACETYLCHOLINESTERASE-RXN", "RHEA:17561", "Reactome:R-HSA-372519" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "AcCholE", "acetyl.beta-methylcholinesterase activity", "acetylcholine acetylhydrolase activity", "acetylcholine hydrolase activity", "acetylthiocholinesterase activity", "choline esterase I activity", "true cholinesterase activity" ; oboInOwl:id "GO:0003990" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "acetylcholinesterase activity" ; rdfs:subClassOf obo:GO_0004104 . obo:GO_0004104 obo:IAO_0000115 "Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion." ; oboInOwl:hasDbXref "EC:3.1.1.8", "MetaCyc:CHOLINESTERASE-RXN", "RHEA:21964" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "BtChoEase activity", "acylcholine acylhydrolase activity", "anticholineesterase activity", "benzoylcholinesterase activity", "butyrylcholine esterase activity", "butyrylcholinesterase activity", "choline esterase II (unspecific) activity", "choline esterase activity", "non-specific cholinesterase activity", "propionylcholinesterase activity", "pseudocholinesterase activity" ; oboInOwl:id "GO:0004104" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "cholinesterase activity" ; rdfs:subClassOf obo:GO_0052689 . obo:GO_0004518 obo:IAO_0000115 "Catalysis of the hydrolysis of ester linkages within nucleic acids." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0004518" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis." ; rdfs:label "nuclease activity" ; rdfs:subClassOf obo:GO_0016788 . obo:GO_0004536 obo:IAO_0000115 "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid." ; oboInOwl:hasAlternativeId "GO:0004537" ; oboInOwl:hasDbXref "Reactome:R-HSA-211247", "Reactome:R-HSA-5685994", "Reactome:R-HSA-6785986" ; oboInOwl:hasExactSynonym "deoxyribonuclease activity" ; oboInOwl:hasNarrowSynonym "caspase-activated deoxyribonuclease activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0004536" ; a owl:Class ; rdfs:label "DNA nuclease activity" ; rdfs:subClassOf obo:GO_0004518, obo:GO_0140097, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006259 ] . obo:GO_0005102 obo:IAO_0000115 "Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." ; oboInOwl:hasBroadSynonym "receptor binding" ; oboInOwl:hasDbXref "Wikipedia:Ligand_(biochemistry)" ; oboInOwl:hasNarrowSynonym "receptor ligand" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "receptor-associated protein activity" ; oboInOwl:id "GO:0005102" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_plant ; a owl:Class ; rdfs:comment "Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'." ; rdfs:label "signaling receptor binding" ; rdfs:subClassOf obo:GO_0005515 . obo:GO_0005126 obo:IAO_0000115 "Binding to a cytokine receptor." ; oboInOwl:hasExactSynonym "hematopoietin/interferon-class (D200-domain) cytokine receptor binding" ; oboInOwl:hasNarrowSynonym "hematopoietin/interferon-class (D200-domain) cytokine receptor ligand" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005126" ; a owl:Class ; rdfs:label "cytokine receptor binding" ; rdfs:subClassOf obo:GO_0005102 . obo:GO_0005172 obo:IAO_0000115 "Binding to a vascular endothelial growth factor receptor." ; oboInOwl:hasExactSynonym "VEGF receptor binding", "VEGFR binding" ; oboInOwl:hasNarrowSynonym "vascular endothelial growth factor", "vascular endothelial growth factor receptor ligand" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005172" ; a owl:Class ; rdfs:label "vascular endothelial growth factor receptor binding" ; rdfs:subClassOf obo:GO_0005126, obo:GO_0070851, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000001971 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000001971 ] ) ] . obo:GO_0005215 obo:IAO_0000115 "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells." ; oboInOwl:hasAlternativeId "GO:0005478" ; oboInOwl:hasDbXref "Reactome:R-HSA-168313", "Reactome:R-HSA-178215" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "carrier" ; oboInOwl:id "GO:0005215" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules." ; rdfs:label "transporter activity" ; rdfs:subClassOf obo:GO_0003674 . obo:GO_0005275 obo:IAO_0000115 "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group." ; oboInOwl:hasAlternativeId "GO:0005279" ; oboInOwl:hasBroadSynonym "amine/amide/polyamine channel activity" ; oboInOwl:hasExactSynonym "amine/polyamine transmembrane transporter activity", "amino acid-polyamine transmembrane transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005275" ; a owl:Class ; rdfs:label "amine transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015837 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32952 ] ) ] . obo:GO_0005277 obo:IAO_0000115 "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." ; oboInOwl:hasDbXref "Reactome:R-HSA-264615" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005277" ; a owl:Class ; rdfs:label "acetylcholine transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0005326, obo:GO_0015101, obo:GO_1901375, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15355 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15355 ] ) ] . obo:GO_0005310 obo:IAO_0000115 "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups." ; oboInOwl:hasAlternativeId "GO:0005312", "GO:0015365" ; oboInOwl:hasDbXref "Reactome:R-HSA-1614546", "Reactome:R-HSA-372843" ; oboInOwl:hasNarrowSynonym "dicarboxylate carrier", "sodium:dicarboxylate/tricarboxylate symporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "dicarboxylate (succinate/fumarate/malate) antiporter activity", "dicarboxylic acid permease activity" ; oboInOwl:id "GO:0005310" ; a owl:Class ; rdfs:label "dicarboxylic acid transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0005342, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006835 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35692 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf _:genid15310 ] . obo:GO_0005319 obo:IAO_0000115 "Enables the directed movement of lipids into, out of or within a cell, or between cells." ; oboInOwl:hasDbXref "Reactome:R-HSA-1369028", "Reactome:R-HSA-1369052", "Reactome:R-HSA-174786", "Reactome:R-HSA-5682285", "Reactome:R-HSA-5682311", "Reactome:R-HSA-5683672", "Reactome:R-HSA-5683714", "Reactome:R-HSA-5688397", "Reactome:R-HSA-6801250", "Reactome:R-HSA-8848053", "Reactome:R-HSA-8866329" ; oboInOwl:hasNarrowSynonym "lipophorin" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "apolipoprotein" ; oboInOwl:id "GO:0005319" ; a owl:Class ; rdfs:label "lipid transporter activity" ; rdfs:subClassOf obo:GO_0005215, _:genid15310, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005215 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0005326 obo:IAO_0000115 "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." ; oboInOwl:hasDbXref "Reactome:R-HSA-374896", "Reactome:R-HSA-374919" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "neurotransmitter transporter activity" ; oboInOwl:id "GO:0005326" ; a owl:Class ; rdfs:label "neurotransmitter transmembrane transporter activity" ; rdfs:subClassOf _:genid15325 . obo:GO_0005342 obo:IAO_0000115 "Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005342" ; a owl:Class ; rdfs:label "organic acid transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_1903825 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64709 ] ) ] . obo:GO_0005355 obo:IAO_0000115 "Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other." ; oboInOwl:hasAlternativeId "GO:0015579" ; oboInOwl:hasDbXref "Reactome:R-HSA-499981", "Reactome:R-HSA-5653873" ; oboInOwl:hasExactSynonym "glucose permease activity" ; oboInOwl:hasNarrowSynonym "lactose/glucose efflux transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "galactose/glucose (methylgalactoside) porter activity" ; oboInOwl:id "GO:0005355" ; a owl:Class ; rdfs:label "glucose transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015149, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_1904659 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17234 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17234 ] ) ] . obo:GO_0005488 obo:IAO_0000115 "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." ; oboInOwl:hasDbXref "Wikipedia:Binding_(molecular)" ; oboInOwl:hasNarrowSynonym "ligand" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005488" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children." ; rdfs:label "binding" ; rdfs:subClassOf obo:GO_0003674 . obo:GO_0005496 obo:IAO_0000115 "Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005496" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "steroid binding" ; rdfs:subClassOf obo:GO_0008289, obo:GO_0097159, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35341 ] ) ] . obo:GO_0005509 obo:IAO_0000115 "Binding to a calcium ion (Ca2+)." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "calcium ion storage activity" ; oboInOwl:id "GO:0005509" ; a owl:Class ; rdfs:label "calcium ion binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_29108 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_29108 ] ) ] . obo:GO_0005515 obo:IAO_0000115 "Binding to a protein." ; oboInOwl:hasAlternativeId "GO:0001948", "GO:0045308" ; oboInOwl:hasExactSynonym "protein amino acid binding" ; oboInOwl:hasNarrowSynonym "glycoprotein binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005515" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "protein binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000000001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0005518 obo:IAO_0000115 "Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005518" ; a owl:Class ; rdfs:label "collagen binding" ; rdfs:subClassOf obo:GO_0044877, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005581 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005581 ] ) ] . obo:GO_0005536 obo:IAO_0000115 "Binding to D- or L-enantiomers of glucose." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005536" ; a owl:Class ; rdfs:label "glucose binding" ; rdfs:subClassOf obo:GO_0030246, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_17234 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_17234 ] ) ] . obo:GO_0005539 obo:IAO_0000115 "Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005539" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "glycosaminoglycan binding" ; rdfs:subClassOf obo:GO_0097367, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18085 ] ) ] . obo:GO_0005540 obo:IAO_0000115 "Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine." ; oboInOwl:hasExactSynonym "hyaluronan binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005540" ; a owl:Class ; rdfs:label "hyaluronic acid binding" ; rdfs:subClassOf obo:GO_0005539, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16336 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf _:genid15394 ] . obo:GO_0005575 obo:IAO_0000115 "A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome)." ; oboInOwl:hasAlternativeId "GO:0008372" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1337158144" ; oboInOwl:hasExactSynonym "cell or subcellular entity", "cellular component" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "subcellular entity" ; oboInOwl:id "GO:0005575" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ; rdfs:label "cellular_component" ; rdfs:subClassOf obo:BFO_0000040 ; owl:disjointWith obo:GO_0008150 . obo:GO_0005576 obo:IAO_0000115 "The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite." ; oboInOwl:hasDbXref "Wikipedia:Extracellular" ; oboInOwl:hasExactSynonym "extracellular" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005576" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'." ; rdfs:label "extracellular region" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0005577 obo:IAO_0000115 "A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds." ; oboInOwl:hasExactSynonym "fibrinogen" ; oboInOwl:hasNarrowSynonym "fibrinogen alpha chain", "fibrinogen beta chain", "fibrinogen gamma chain" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005577" ; a owl:Class ; rdfs:label "fibrinogen complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005615 ] . obo:GO_0005581 obo:IAO_0000115 "A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures." ; oboInOwl:hasDbXref "Wikipedia:Collagen" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005581" ; a owl:Class ; rdfs:label "collagen trimer" ; rdfs:subClassOf obo:GO_0032991, _:genid15394, _:genid15396 . obo:GO_0005583 obo:IAO_0000115 "Any triple helical collagen trimer that forms fibrils." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005583" ; a owl:Class ; rdfs:label "fibrillar collagen trimer" ; rdfs:subClassOf obo:GO_0005581, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098643 ] ; owl:disjointWith obo:GO_0030936 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005581 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098643 ] ) ] . obo:GO_0005585 obo:IAO_0000115 "A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils." ; oboInOwl:hasDbXref "Wikipedia:Collagen_type_II" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005585" ; a owl:Class ; rdfs:label "collagen type II trimer" ; rdfs:subClassOf obo:GO_0005583 . obo:GO_0005587 obo:IAO_0000115 "A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes." ; oboInOwl:hasDbXref "Wikipedia:Collagen_type_IV" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005587" ; a owl:Class ; rdfs:label "collagen type IV trimer" ; rdfs:subClassOf obo:GO_0098642, obo:GO_0098651 . obo:GO_0005604 obo:IAO_0000115 "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." ; oboInOwl:hasAlternativeId "GO:0005605", "GO:0008003" ; oboInOwl:hasDbXref "Wikipedia:Basement_membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "basal lamina", "basement lamina", "lamina densa" ; oboInOwl:id "GO:0005604" ; a owl:Class ; rdfs:comment "Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer." ; rdfs:label "basement membrane" ; rdfs:subClassOf obo:GO_0062023 . obo:GO_0005615 obo:IAO_0000115 "That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1425028079" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "intercellular space" ; oboInOwl:id "GO:0005615" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term." ; rdfs:label "extracellular space" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005576 ] . obo:GO_0005622 obo:IAO_0000115 "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17776"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Intracellular" ; oboInOwl:hasExactSynonym "internal to cell", "intracellular", "protoplasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "nucleocytoplasm", "protoplast" ; oboInOwl:id "GO:0005622" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_chembl, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:label "intracellular anatomical structure" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000000 ] . obo:GO_0005623 obo:IAO_0000115 "OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19036"^^xsd:anyURI ; obo:IAO_0000589 "cell and encapsulating structures" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1813327414", "Wikipedia:Cell_(biology)" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005623" ; a owl:Class ; rdfs:comment "This term was obsoleted because it was redundant with the root class of the cell ontology, CL:0000000." ; rdfs:label "obsolete cell" ; owl:deprecated true . obo:GO_0005634 obo:IAO_0000115 "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1702920020", "Wikipedia:Cell_nucleus" ; oboInOwl:hasExactSynonym "cell nucleus" ; oboInOwl:hasNarrowSynonym "horsetail nucleus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005634" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "nucleus" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith obo:GO_0005737, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0005635 obo:IAO_0000115 "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." ; oboInOwl:hasAlternativeId "GO:0005636" ; oboInOwl:hasDbXref "Wikipedia:Nuclear_envelope" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005635" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic, go:goslim_plant ; a owl:Class ; rdfs:label "nuclear envelope" ; rdfs:subClassOf obo:GO_0031967, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0005640 obo:IAO_0000115 "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1617136075" ; oboInOwl:hasExactSynonym "nucleus outer envelope", "perinuclear membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005640" ; a owl:Class ; rdfs:label "nuclear outer membrane" ; rdfs:subClassOf obo:GO_0031965, obo:GO_0031968, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042175 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0005643 obo:IAO_0000115 "A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined." ; oboInOwl:hasAlternativeId "GO:0005644" ; oboInOwl:hasDbXref "NIF_Subcellular:sao220861693", "Wikipedia:Nuclear_pore" ; oboInOwl:hasExactSynonym "NPC", "nuclear pore complex", "nucleopore" ; oboInOwl:hasNarrowSynonym "nuclear pore membrane protein" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005643" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "nuclear pore" ; rdfs:subClassOf obo:GO_0140513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005635 ] . obo:GO_0005694 obo:IAO_0000115 "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." ; oboInOwl:hasDbXref "Wikipedia:Chromosome" ; oboInOwl:hasNarrowSynonym "interphase chromosome", "prophase chromosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "chromatid" ; oboInOwl:id "GO:0005694" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ; rdfs:label "chromosome" ; rdfs:subClassOf obo:GO_0043232 . obo:GO_0005712 obo:IAO_0000115 "A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over." ; oboInOwl:hasDbXref "Wikipedia:Chiasma_(genetics)" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005712" ; a owl:Class ; rdfs:label "chiasma" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000794 ] . obo:GO_0005730 obo:IAO_0000115 "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1820400233", "Wikipedia:Nucleolus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005730" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "nucleolus" ; rdfs:subClassOf obo:GO_0043232, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031981 ] . obo:GO_0005737 obo:IAO_0000115 "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23023"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Cytoplasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005737" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "cytoplasm" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] . obo:GO_0005739 obo:IAO_0000115 "A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1860313010", "Wikipedia:Mitochondrion" ; oboInOwl:hasExactSynonym "mitochondria" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005739" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.)" ; rdfs:label "mitochondrion" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0005740 obo:IAO_0000115 "The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005740" ; oboInOwl:inSubset go:goslim_candida, go:goslim_yeast ; a owl:Class ; rdfs:label "mitochondrial envelope" ; rdfs:subClassOf obo:GO_0031967, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] . obo:GO_0005759 obo:IAO_0000115 "The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation." ; oboInOwl:hasAlternativeId "GO:0031980" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1804523077", "Wikipedia:Mitochondrial_matrix" ; oboInOwl:hasExactSynonym "mitochondrial lumen" ; oboInOwl:hasNarrowSynonym "mitochondrial stroma" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005759" ; a owl:Class ; rdfs:label "mitochondrial matrix" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] . obo:GO_0005764 obo:IAO_0000115 "A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "NIF_Subcellular:sao585356902", "Wikipedia:Lysosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005764" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic, go:goslim_plant ; a owl:Class ; rdfs:label "lysosome" ; rdfs:subClassOf obo:GO_0000323, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] . obo:GO_0005765 obo:IAO_0000115 "The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasExactSynonym "lysosome membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005765" ; a owl:Class ; rdfs:label "lysosomal membrane" ; rdfs:subClassOf obo:GO_0098852, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005764 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005764 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005764 ] ) ] . obo:GO_0005768 obo:IAO_0000115 "A vacuole to which materials ingested by endocytosis are delivered." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1720343330", "Wikipedia:Endosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005768" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "endosome" ; rdfs:subClassOf obo:GO_0031410, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0005769 obo:IAO_0000115 "A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways." ; oboInOwl:hasDbXref "NIF_Subcellular:nlx_subcell_20090701" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005769" ; a owl:Class ; rdfs:label "early endosome" ; rdfs:subClassOf obo:GO_0005768 . obo:GO_0005770 obo:IAO_0000115 "A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center." ; oboInOwl:hasBroadSynonym "PVC" ; oboInOwl:hasDbXref "NIF_Subcellular:nlx_subcell_20090702" ; oboInOwl:hasExactSynonym "prevacuolar compartment" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005770" ; a owl:Class ; rdfs:label "late endosome" ; rdfs:subClassOf obo:GO_0005768 . obo:GO_0005773 obo:IAO_0000115 "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." ; oboInOwl:hasDbXref "Wikipedia:Vacuole" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "vacuolar carboxypeptidase Y" ; oboInOwl:id "GO:0005773" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "vacuole" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0005774 obo:IAO_0000115 "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005774" ; a owl:Class ; rdfs:label "vacuolar membrane" ; rdfs:subClassOf obo:GO_0098588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005773 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0005775 obo:IAO_0000115 "The volume enclosed within the vacuolar membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005775" ; a owl:Class ; rdfs:label "vacuolar lumen" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031974 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0005777 obo:IAO_0000115 "A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism." ; oboInOwl:hasAlternativeId "GO:0019818" ; oboInOwl:hasBroadSynonym "peroxisome vesicle" ; oboInOwl:hasDbXref "NIF_Subcellular:sao499555322", "Wikipedia:Peroxisome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "peroxisomal" ; oboInOwl:id "GO:0005777" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "peroxisome" ; rdfs:subClassOf obo:GO_0042579 . obo:GO_0005783 obo:IAO_0000115 "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1036339110", "Wikipedia:Endoplasmic_reticulum" ; oboInOwl:hasExactSynonym "ER" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005783" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "endoplasmic reticulum" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0005788 obo:IAO_0000115 "The volume enclosed by the membranes of the endoplasmic reticulum." ; oboInOwl:hasAlternativeId "GO:0016022" ; oboInOwl:hasExactSynonym "ER cisterna", "ER lumen", "cisternal lumen", "endoplasmic reticulum cisterna" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005788" ; a owl:Class ; rdfs:label "endoplasmic reticulum lumen" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005783 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031974 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005783 ] ) ] . obo:GO_0005794 obo:IAO_0000115 "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways." ; oboInOwl:hasBroadSynonym "Golgi" ; oboInOwl:hasDbXref "NIF_Subcellular:sao451912436", "Wikipedia:Golgi_apparatus" ; oboInOwl:hasExactSynonym "Golgi complex" ; oboInOwl:hasNarrowSynonym "Golgi ribbon" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005794" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon." ; rdfs:label "Golgi apparatus" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0005798 obo:IAO_0000115 "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell." ; oboInOwl:hasDbXref "NIF_Subcellular:sao819927218" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "Golgi vesicle", "vesicular component" ; oboInOwl:id "GO:0005798" ; a owl:Class ; rdfs:comment "Note that this definition includes vesicles that are transiently associated with the Golgi." ; rdfs:label "Golgi-associated vesicle" ; rdfs:subClassOf obo:GO_0031410 . obo:GO_0005818 obo:IAO_0000115 "An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005818" ; a owl:Class ; rdfs:label "aster" ; rdfs:subClassOf obo:GO_0043232, obo:GO_0099080, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005819 ] . obo:GO_0005819 obo:IAO_0000115 "The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart." ; oboInOwl:hasDbXref "Wikipedia:Spindle_apparatus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005819" ; a owl:Class ; rdfs:label "spindle" ; rdfs:subClassOf obo:GO_0043232, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015630 ] . obo:GO_0005829 obo:IAO_0000115 "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." ; oboInOwl:hasDbXref "NIF_Subcellular:sao101633890", "Wikipedia:Cytosol" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005829" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_plant ; a owl:Class ; rdfs:label "cytosol" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0005840 obo:IAO_0000115 "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins." ; oboInOwl:hasAlternativeId "GO:0033279" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1429207766", "Wikipedia:Ribosome" ; oboInOwl:hasNarrowSynonym "free ribosome", "membrane bound ribosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "ribosomal RNA" ; oboInOwl:id "GO:0005840" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "ribosome" ; rdfs:subClassOf obo:GO_0043232, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33697 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0006412 ] . obo:GO_0005856 obo:IAO_0000115 "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." ; oboInOwl:hasDbXref "Wikipedia:Cytoskeleton" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005856" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "cytoskeleton" ; rdfs:subClassOf obo:GO_0043232 . obo:GO_0005859 obo:IAO_0000115 "A filament of myosin found in a muscle cell of any type." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005859" ; a owl:Class ; rdfs:label "muscle myosin complex" ; rdfs:subClassOf obo:GO_0016460, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043292 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016460 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043292 ] ) ] . obo:GO_0005863 obo:IAO_0000115 "Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005863" ; a owl:Class ; rdfs:label "striated muscle myosin thick filament" ; rdfs:subClassOf obo:GO_0032982, obo:GO_0036379, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030017 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005859 ] . obo:GO_0005874 obo:IAO_0000115 "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1846835077", "Wikipedia:Microtubule" ; oboInOwl:hasExactSynonym "microtubuli", "microtubulus" ; oboInOwl:hasNarrowSynonym "neurotubule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005874" ; oboInOwl:inSubset go:goslim_metagenomics ; a owl:Class ; rdfs:label "microtubule" ; rdfs:subClassOf obo:GO_0099513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015630 ] . obo:GO_0005876 obo:IAO_0000115 "Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005876" ; a owl:Class ; rdfs:label "spindle microtubule" ; rdfs:subClassOf obo:GO_0005874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005819 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005874 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005819 ] ) ] . obo:GO_0005879 obo:IAO_0000115 "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005879" ; a owl:Class ; rdfs:label "axonemal microtubule" ; rdfs:subClassOf obo:GO_0005881, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005930 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005874 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005930 ] ) ] . obo:GO_0005880 obo:IAO_0000115 "Any microtubule in the nucleus of a cell." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005880" ; a owl:Class ; rdfs:label "nuclear microtubule" ; rdfs:subClassOf obo:GO_0005874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005874 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0005881 obo:IAO_0000115 "Any microtubule in the cytoplasm of a cell." ; oboInOwl:hasNarrowSynonym "non-spindle-associated astral microtubule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005881" ; a owl:Class ; rdfs:label "cytoplasmic microtubule" ; rdfs:subClassOf obo:GO_0005874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005874 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0005884 obo:IAO_0000115 "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." ; oboInOwl:hasDbXref "FMA:63850", "NIF_Subcellular:sao1588493326", "Wikipedia:Actin" ; oboInOwl:hasExactSynonym "microfilament" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005884" ; a owl:Class ; rdfs:label "actin filament" ; rdfs:subClassOf obo:GO_0099513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015629 ] . obo:GO_0005886 obo:IAO_0000115 "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." ; oboInOwl:hasAlternativeId "GO:0005887", "GO:0005904" ; oboInOwl:hasBroadSynonym "juxtamembrane" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1663586795", "Wikipedia:Cell_membrane" ; oboInOwl:hasExactSynonym "cell membrane", "cellular membrane", "cytoplasmic membrane", "plasmalemma" ; oboInOwl:hasNarrowSynonym "bacterial inner membrane", "inner endospore membrane", "integral component of plasma membrane", "integral to plasma membrane", "plasma membrane lipid bilayer" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005886" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "plasma membrane" ; rdfs:subClassOf obo:GO_0016020, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071944 ] . obo:GO_0005902 obo:IAO_0000115 "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "NIF_Subcellular:sao671419673", "Wikipedia:Microvillus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "microvilli" ; oboInOwl:id "GO:0005902" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta." ; rdfs:label "microvillus" ; rdfs:subClassOf obo:GO_0098858, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000066 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0032432 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] . obo:GO_0005911 obo:IAO_0000115 "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22122"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "cell-cell contact region", "cell-cell contact zone" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1922892319" ; oboInOwl:hasExactSynonym "intercellular junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005911" ; a owl:Class ; rdfs:label "cell-cell junction" ; rdfs:subClassOf obo:GO_0070161 . obo:GO_0005912 obo:IAO_0000115 "A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules." ; oboInOwl:hasAlternativeId "GO:0005913" ; oboInOwl:hasDbXref "Wikipedia:Adherens_junction" ; oboInOwl:hasExactSynonym "cell-cell adherens junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005912" ; a owl:Class ; rdfs:label "adherens junction" ; rdfs:subClassOf obo:GO_0005911 . obo:GO_0005923 obo:IAO_0000115 "An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1939999134", "Wikipedia:Tight_junction" ; oboInOwl:hasExactSynonym "zonula occludens" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005923" ; a owl:Class ; rdfs:label "bicellular tight junction" ; rdfs:subClassOf obo:GO_0070160, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043296 ] . obo:GO_0005929 obo:IAO_0000115 "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." ; obo:RO_0002161 obo:NCBITaxon_3176, obo:NCBITaxon_3312, obo:NCBITaxon_3378, obo:NCBITaxon_3398, obo:NCBITaxon_4890, obo:NCBITaxon_5782 ; oboInOwl:hasAlternativeId "GO:0072372" ; oboInOwl:hasDbXref "FMA:67181", "NIF_Subcellular:sao787716553", "Wikipedia:Cilium" ; oboInOwl:hasExactSynonym "eukaryotic flagellum", "microtubule-based flagellum" ; oboInOwl:hasNarrowSynonym "primary cilium" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "flagellum" ; oboInOwl:id "GO:0005929" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms." ; rdfs:label "cilium" ; rdfs:subClassOf obo:GO_0043227, obo:GO_0120025, obo:PR_000050567, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030990 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3176 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3312 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3378 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3398 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4890 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] . obo:GO_0005930 obo:IAO_0000115 "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." ; oboInOwl:hasAlternativeId "GO:0035085", "GO:0035086" ; oboInOwl:hasDbXref "Wikipedia:Axoneme" ; oboInOwl:hasExactSynonym "ciliary axoneme", "cilium axoneme", "flagellar axoneme", "flagellum axoneme" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005930" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane." ; rdfs:label "axoneme" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005856 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0097014 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005874 ] . obo:GO_0005938 obo:IAO_0000115 "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." ; oboInOwl:hasDbXref "Wikipedia:Cell_cortex" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cell periphery", "peripheral cytoplasm" ; oboInOwl:id "GO:0005938" ; oboInOwl:inSubset go:goslim_candida, go:goslim_yeast ; a owl:Class ; rdfs:label "cell cortex" ; rdfs:subClassOf obo:GO_0005737, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071944 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071944 ] ) ] . obo:GO_0005975 obo:IAO_0000115 "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22880"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-10-23T15:40:34Z" ; oboInOwl:hasAlternativeId "GO:0044261", "GO:0044723" ; oboInOwl:hasDbXref "Wikipedia:Carbohydrate_metabolism" ; oboInOwl:hasExactSynonym "carbohydrate metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0005975" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "carbohydrate metabolic process" ; rdfs:subClassOf obo:GO_0044238, obo:GO_0071704, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_16646 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_16646 ] ) ] . obo:GO_0005976 obo:IAO_0000115 "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ; oboInOwl:hasAlternativeId "GO:0044263" ; oboInOwl:hasExactSynonym "polysaccharide metabolism" ; oboInOwl:hasNarrowSynonym "glycan metabolic process", "glycan metabolism", "multicellular organismal polysaccharide metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0005976" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "polysaccharide metabolic process" ; rdfs:subClassOf obo:GO_0005975, obo:GO_0043170, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18154 ] ) ] . obo:GO_0005977 obo:IAO_0000115 "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages." ; oboInOwl:hasExactSynonym "glycogen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0005977" ; a owl:Class ; rdfs:label "glycogen metabolic process" ; rdfs:subClassOf obo:GO_0006112, obo:GO_0044042, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_28087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_28087 ] ) ] . obo:GO_0005978 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." ; oboInOwl:hasDbXref "MetaCyc:GLYCOGENSYNTH-PWY" ; oboInOwl:hasExactSynonym "glycogen anabolism", "glycogen biosynthesis", "glycogen formation", "glycogen synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0005978" ; a owl:Class ; rdfs:label "glycogen biosynthetic process" ; rdfs:subClassOf obo:GO_0005977, obo:GO_0009250, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_28087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_28087 ] ) ] . obo:GO_0005979 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." ; oboInOwl:hasExactSynonym "regulation of glycogen anabolism", "regulation of glycogen biosynthesis", "regulation of glycogen formation", "regulation of glycogen synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0005979" ; a owl:Class ; rdfs:label "regulation of glycogen biosynthetic process" ; rdfs:subClassOf obo:GO_0010962, obo:GO_0070873, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005978 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005978 ] ) ] . obo:GO_0005980 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues." ; oboInOwl:hasDbXref "MetaCyc:GLYCOCAT-PWY" ; oboInOwl:hasExactSynonym "glycogen breakdown", "glycogen catabolism", "glycogen degradation", "glycogenolysis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0005980" ; a owl:Class ; rdfs:label "glycogen catabolic process" ; rdfs:subClassOf obo:GO_0005977, obo:GO_0009251, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_28087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_28087 ] ) ] . obo:GO_0005981 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." ; oboInOwl:hasExactSynonym "regulation of glycogen breakdown", "regulation of glycogen catabolism", "regulation of glycogen degradation", "regulation of glycogenolysis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0005981" ; a owl:Class ; rdfs:label "regulation of glycogen catabolic process" ; rdfs:subClassOf obo:GO_0043470, obo:GO_0070873, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005980 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005980 ] ) ] . obo:GO_0005996 obo:IAO_0000115 "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." ; oboInOwl:hasExactSynonym "monosaccharide metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0005996" ; a owl:Class ; rdfs:label "monosaccharide metabolic process" ; rdfs:subClassOf obo:GO_0005975, obo:GO_0044281, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35381 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35381 ] ) ] . obo:GO_0006006 obo:IAO_0000115 "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides." ; oboInOwl:hasExactSynonym "cellular glucose metabolic process", "glucose metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006006" ; a owl:Class ; rdfs:label "glucose metabolic process" ; rdfs:subClassOf obo:GO_0019318, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_17234 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_17234 ] ) ] . obo:GO_0006007 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose." ; oboInOwl:hasExactSynonym "glucose breakdown", "glucose catabolism", "glucose degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006007" ; a owl:Class ; rdfs:label "glucose catabolic process" ; rdfs:subClassOf obo:GO_0006006, obo:GO_0019320, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17234 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17234 ] ) ] . obo:GO_0006022 obo:IAO_0000115 "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." ; oboInOwl:hasExactSynonym "aminoglycan metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006022" ; a owl:Class ; rdfs:label "aminoglycan metabolic process" ; rdfs:subClassOf obo:GO_0043170, obo:GO_1901135, obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_22506 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_22506 ] ) ] . obo:GO_0006023 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." ; oboInOwl:hasExactSynonym "aminoglycan anabolism", "aminoglycan biosynthesis", "aminoglycan formation", "aminoglycan synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006023" ; a owl:Class ; rdfs:label "aminoglycan biosynthetic process" ; rdfs:subClassOf obo:GO_0006022, obo:GO_0009059, obo:GO_1901137, obo:GO_1901566, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_22506 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_22506 ] ) ] . obo:GO_0006024 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." ; oboInOwl:hasExactSynonym "glycosaminoglycan anabolism", "glycosaminoglycan biosynthesis", "glycosaminoglycan formation", "glycosaminoglycan synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006024" ; a owl:Class ; rdfs:label "glycosaminoglycan biosynthetic process" ; rdfs:subClassOf obo:GO_0006023, obo:GO_0030203, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18085 ] ) ] . obo:GO_0006026 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages." ; oboInOwl:hasExactSynonym "aminoglycan breakdown", "aminoglycan catabolism", "aminoglycan degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006026" ; a owl:Class ; rdfs:label "aminoglycan catabolic process" ; rdfs:subClassOf obo:GO_0006022, obo:GO_0009057, obo:GO_1901136, obo:GO_1901565, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_22506 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_22506 ] ) ] . obo:GO_0006027 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars." ; oboInOwl:hasExactSynonym "glycosaminoglycan breakdown", "glycosaminoglycan catabolism", "glycosaminoglycan degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006027" ; a owl:Class ; rdfs:label "glycosaminoglycan catabolic process" ; rdfs:subClassOf obo:GO_0006026, obo:GO_0030203, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18085 ] ) ] . obo:GO_0006066 obo:IAO_0000115 "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." ; oboInOwl:hasExactSynonym "alcohol metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006066" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:label "alcohol metabolic process" ; rdfs:subClassOf obo:GO_0044281, obo:GO_1901615 . obo:GO_0006082 obo:IAO_0000115 "The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage." ; oboInOwl:hasExactSynonym "organic acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006082" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "organic acid metabolic process" ; rdfs:subClassOf obo:GO_0044237, obo:GO_0044281, obo:GO_0071704, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_64709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_64709 ] ) ] . obo:GO_0006083 obo:IAO_0000115 "The chemical reactions and pathways involving acetate, the anion of acetic acid." ; oboInOwl:hasExactSynonym "acetate metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006083" ; a owl:Class ; rdfs:label "acetate metabolic process" ; rdfs:subClassOf obo:GO_0032787, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_30089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_30089 ] ) ] . obo:GO_0006091 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances." ; oboInOwl:hasBroadSynonym "energy pathways" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intermediary metabolism", "metabolic energy generation" ; oboInOwl:id "GO:0006091" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "generation of precursor metabolites and energy" ; rdfs:subClassOf obo:GO_0044237 . obo:GO_0006094 obo:IAO_0000115 "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." ; oboInOwl:hasDbXref "MetaCyc:GLUCONEO-PWY", "Wikipedia:Gluconeogenesis" ; oboInOwl:hasExactSynonym "glucose biosynthesis", "glucose biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006094" ; a owl:Class ; rdfs:label "gluconeogenesis" ; rdfs:subClassOf obo:GO_0006006, obo:GO_0019319, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_17234 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_17234 ] ) ] . obo:GO_0006109 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates." ; oboInOwl:hasExactSynonym "regulation of carbohydrate metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006109" ; a owl:Class ; rdfs:label "regulation of carbohydrate metabolic process" ; rdfs:subClassOf obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005975 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005975 ] ) ] . obo:GO_0006111 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2013-01-18T12:47:43Z" ; oboInOwl:hasAlternativeId "GO:0090526" ; oboInOwl:hasBroadSynonym "regulation of glucose biosynthesis", "regulation of glucose biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of gluconeogenesis involved in cellular glucose homeostasis" ; oboInOwl:id "GO:0006111" ; a owl:Class ; rdfs:label "regulation of gluconeogenesis" ; rdfs:subClassOf obo:GO_0010906, obo:GO_0043255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006094 ] ) ] . obo:GO_0006112 obo:IAO_0000115 "The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen." ; oboInOwl:hasExactSynonym "energy reserve metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006112" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "energy reserve metabolic process" ; rdfs:subClassOf obo:GO_0015980 . obo:GO_0006139 obo:IAO_0000115 "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasAlternativeId "GO:0055134" ; oboInOwl:hasExactSynonym "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism", "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nucleobase, nucleoside and nucleotide metabolic process", "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:id "GO:0006139" ; oboInOwl:inSubset go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "nucleobase-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_0034641, obo:GO_0044238, obo:GO_0046483, obo:GO_1901360, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_61120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_61120 ] ) ] . obo:GO_0006259 obo:IAO_0000115 "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides." ; oboInOwl:hasAlternativeId "GO:0055132" ; oboInOwl:hasExactSynonym "DNA metabolism", "cellular DNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006259" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "DNA metabolic process" ; rdfs:subClassOf obo:GO_0090304, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_16991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_16991 ] ) ] . obo:GO_0006260 obo:IAO_0000115 "The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/10596"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0055133" ; oboInOwl:hasDbXref "Wikipedia:DNA_replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006260" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:comment "DNA biosynthesis is only part of this process. See also the biological process terms 'DNA-dependent DNA replication ; GO:0006261' and 'RNA-dependent DNA replication ; GO:0006278'." ; rdfs:label "DNA replication" ; rdfs:subClassOf obo:GO_0006259, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0071897 ] . obo:GO_0006261 obo:IAO_0000115 "A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22572"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006262", "GO:0006263" ; oboInOwl:hasExactSynonym "DNA-dependent DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006261" ; a owl:Class ; rdfs:label "DNA-templated DNA replication" ; rdfs:subClassOf obo:GO_0006260 . obo:GO_0006264 obo:IAO_0000115 "The process in which new strands of DNA are synthesized in the mitochondrion." ; oboInOwl:hasExactSynonym "mtDNA replication", "replication of mitochondrial DNA" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitochondrial DNA synthesis", "mtDNA synthesis" ; oboInOwl:id "GO:0006264" ; a owl:Class ; rdfs:label "mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0006261, obo:GO_0032042 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006260 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0006270 obo:IAO_0000115 "The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/10596"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0042024" ; oboInOwl:hasExactSynonym "DNA-dependent DNA replication initiation" ; oboInOwl:hasNarrowSynonym "DNA endoreduplication initiation", "DNA re-replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006270" ; a owl:Class ; rdfs:label "DNA replication initiation" ; rdfs:subClassOf obo:GO_0006259, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006261 ] . obo:GO_0006275 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of DNA replication." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006275" ; a owl:Class ; rdfs:label "regulation of DNA replication" ; rdfs:subClassOf obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006260 ] ) ] . obo:GO_0006279 obo:IAO_0000115 "The replication of DNA that precedes meiotic cell division." ; oboInOwl:hasAlternativeId "GO:1902968" ; oboInOwl:hasExactSynonym "DNA replication involved in S phase involved in meiotic cell cycle", "DNA replication involved in S-phase involved in meiotic cell cycle", "meiotic cell cycle DNA replication", "meiotic nuclear cell cycle DNA replication", "nuclear cell cycle DNA replication involved in meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA replication during S phase involved in meiotic cell cycle", "meiotic DNA replication", "meiotic DNA synthesis", "premeiotic DNA synthesis" ; oboInOwl:id "GO:0006279" ; a owl:Class ; rdfs:label "premeiotic DNA replication" ; rdfs:subClassOf obo:GO_0033260, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0033260 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0006308 obo:IAO_0000115 "The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one." ; oboInOwl:hasExactSynonym "DNA breakdown", "DNA catabolism", "DNA degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006308" ; a owl:Class ; rdfs:label "DNA catabolic process" ; rdfs:subClassOf obo:GO_0006259, obo:GO_0009057, obo:GO_0034655, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0004536 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16991 ] ) ] . obo:GO_0006309 obo:IAO_0000115 "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24396"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0008178" ; oboInOwl:hasBroadSynonym "DNA fragmentation", "chromatinolysis" ; oboInOwl:hasExactSynonym "DNA catabolic process during apoptosis", "DNA catabolism during apoptosis", "DNA fragmentation involved in apoptotic nuclear change", "endonucleolytic DNA catabolic process involved in apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006309" ; a owl:Class ; rdfs:comment "DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases. In human, these include DNA fragmentation factor (DFF) or caspase-activated DNase (CAD) and endonuclease G (Endo G) (reviewed in PMID:15723341). Caution is needed when apoptotic DNA laddering assays show presence of fragmented DNA. A positive assay may simply reflect the end point of a whole apoptotic process. Unless clear experimental evidence is available to show that a gene product is directly involved in fragmenting DNA, please do not annotate to GO:0006309 'apoptotic DNA fragmentation' and consider annotating instead to a more upstream process such as, e.g., GO:0042981 'regulation of apoptotic process', GO:0006915 'apoptotic process', GO:0097190 'apoptotic signaling pathway'. Also, note that gene products involved in compartmentalization of apoptotic nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341)." ; rdfs:label "apoptotic DNA fragmentation" ; rdfs:subClassOf obo:GO_0006308, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030262 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006308 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030262 ] ) ] . obo:GO_0006310 obo:IAO_0000115 "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006310" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "DNA recombination" ; rdfs:subClassOf obo:GO_0006259 . obo:GO_0006325 obo:IAO_0000115 "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22130"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/23549"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006333", "GO:0006336", "GO:0016568", "GO:0031497", "GO:0034724" ; oboInOwl:hasBroadSynonym "chromatin maintenance" ; oboInOwl:hasExactSynonym "chromatin organisation", "establishment of chromatin architecture", "establishment or maintenance of chromatin architecture" ; oboInOwl:hasNarrowSynonym "DNA replication-independent chromatin assembly", "DNA replication-independent chromatin organization", "DNA replication-independent nucleosome organisation", "DNA replication-independent nuclesome assembly", "chromatin assembly", "transcription-coupled nucleosome assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromatin assembly or disassembly", "chromatin assembly/disassembly", "chromatin modification" ; oboInOwl:id "GO:0006325" ; oboInOwl:inSubset go:goslim_generic, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:label "chromatin organization" ; rdfs:subClassOf obo:GO_0071824, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0000785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0000785 ] ) ] . obo:GO_0006338 obo:IAO_0000115 "A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21732"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/21748"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0043044" ; oboInOwl:hasExactSynonym "chromatin modeling", "chromatin modelling", "chromatin remodelling" ; oboInOwl:hasNarrowSynonym "ATP-dependent chromatin remodeling", "ATP-dependent chromatin remodelling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006338" ; a owl:Class ; rdfs:label "chromatin remodeling" ; rdfs:subClassOf obo:GO_0006325 . obo:GO_0006351 obo:IAO_0000115 "The synthesis of an RNA transcript from a DNA template." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14854"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/16737"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/22258"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/22555"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0001121", "GO:0006350", "GO:0061018", "GO:0061022" ; oboInOwl:hasBroadSynonym "cellular transcription", "transcription" ; oboInOwl:hasDbXref "Wikipedia:Transcription_(genetics)" ; oboInOwl:hasExactSynonym "DNA-dependent transcription", "transcription, DNA-dependent", "transcription, DNA-templated" ; oboInOwl:hasNarrowSynonym "bacterial transcription", "transcription from bacterial-type RNA polymerase promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006351" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "DNA-templated transcription" ; rdfs:subClassOf obo:GO_0032774 . obo:GO_0006355 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." ; oboInOwl:hasAlternativeId "GO:0032583", "GO:0045449", "GO:0061019" ; oboInOwl:hasBroadSynonym "transcriptional control" ; oboInOwl:hasExactSynonym "regulation of cellular transcription, DNA-dependent", "regulation of transcription, DNA-dependent", "regulation of transcription, DNA-templated" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of gene-specific transcription" ; oboInOwl:id "GO:0006355" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "regulation of DNA-templated transcription" ; rdfs:subClassOf obo:GO_0010468, obo:GO_2001141, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006351 ] ) ] . obo:GO_0006357 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II." ; oboInOwl:hasAlternativeId "GO:0006358", "GO:0010551" ; oboInOwl:hasExactSynonym "regulation of transcription from Pol II promoter", "regulation of transcription from RNA polymerase II promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "global transcription regulation from Pol II promoter", "regulation of gene-specific transcription from RNA polymerase II promoter", "regulation of global transcription from Pol II promoter", "regulation of transcription from RNA polymerase II promoter, global" ; oboInOwl:id "GO:0006357" ; a owl:Class ; rdfs:label "regulation of transcription by RNA polymerase II" ; rdfs:subClassOf obo:GO_0006355, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006366 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006366 ] ) ] . obo:GO_0006366 obo:IAO_0000115 "The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14854"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0032568", "GO:0032569" ; oboInOwl:hasExactSynonym "transcription from Pol II promoter", "transcription from RNA polymerase II promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "RNA polymerase II transcription factor activity", "gene-specific transcription from RNA polymerase II promoter", "general transcription from RNA polymerase II promoter", "specific transcription from RNA polymerase II promoter" ; oboInOwl:id "GO:0006366" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "transcription by RNA polymerase II" ; rdfs:subClassOf obo:GO_0006351 . obo:GO_0006396 obo:IAO_0000115 "Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules." ; oboInOwl:hasAlternativeId "GO:0006394" ; oboInOwl:hasDbXref "Wikipedia:Post-transcriptional_modification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006396" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:label "RNA processing" ; rdfs:subClassOf obo:GO_0016070, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010467 ] . obo:GO_0006397 obo:IAO_0000115 "Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mRNA maturation" ; oboInOwl:id "GO:0006397" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_yeast ; a owl:Class ; rdfs:label "mRNA processing" ; rdfs:subClassOf obo:GO_0006396, obo:GO_0016071 . obo:GO_0006401 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; oboInOwl:hasExactSynonym "RNA breakdown", "RNA catabolism", "RNA degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006401" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "RNA catabolic process" ; rdfs:subClassOf obo:GO_0009057, obo:GO_0016070, obo:GO_0034655, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33697 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33697 ] ) ] . obo:GO_0006402 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." ; oboInOwl:hasExactSynonym "mRNA breakdown", "mRNA catabolism", "mRNA degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mRNA decay" ; oboInOwl:id "GO:0006402" ; a owl:Class ; rdfs:label "mRNA catabolic process" ; rdfs:subClassOf obo:GO_0006401, obo:GO_0010629, obo:GO_0016071 . obo:GO_0006403 obo:IAO_0000115 "A process in which RNA is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "RNA localisation", "establishment and maintenance of RNA localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006403" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "RNA localization" ; rdfs:subClassOf obo:GO_0033036 . obo:GO_0006405 obo:IAO_0000115 "The directed movement of RNA from the nucleus to the cytoplasm." ; oboInOwl:hasExactSynonym "RNA export from cell nucleus", "RNA export out of nucleus", "RNA transport from nucleus to cytoplasm", "RNA-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006405" ; a owl:Class ; rdfs:label "RNA export from nucleus" ; rdfs:subClassOf obo:GO_0050658, obo:GO_0051168 . obo:GO_0006406 obo:IAO_0000115 "The directed movement of mRNA from the nucleus to the cytoplasm." ; oboInOwl:hasExactSynonym "mRNA export from cell nucleus", "mRNA export out of nucleus", "mRNA transport from nucleus to cytoplasm", "mRNA-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006406" ; a owl:Class ; rdfs:label "mRNA export from nucleus" ; rdfs:subClassOf obo:GO_0006405, obo:GO_0051028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010467 ] . obo:GO_0006412 obo:IAO_0000115 "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." ; oboInOwl:hasAlternativeId "GO:0006416", "GO:0006453", "GO:0043037" ; oboInOwl:hasDbXref "Wikipedia:Translation_(genetics)" ; oboInOwl:hasExactSynonym "protein anabolism", "protein biosynthesis", "protein biosynthetic process", "protein formation", "protein synthesis", "protein translation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006412" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:prokaryote_subset ; a owl:Class ; rdfs:label "translation" ; rdfs:subClassOf obo:GO_0009059, obo:GO_0019538, obo:GO_0043043, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010467 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0006414 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002224 ; owl:someValuesFrom obo:GO_0006413 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002230 ; owl:someValuesFrom obo:GO_0006415 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16541 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010467 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16541 ] ) ] . obo:GO_0006413 obo:IAO_0000115 "The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA." ; oboInOwl:hasAlternativeId "GO:0006440", "GO:0006454" ; oboInOwl:hasBroadSynonym "biopolymerisation", "biopolymerization", "protein synthesis initiation" ; oboInOwl:hasExactSynonym "translation initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006413" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "translational initiation" ; rdfs:subClassOf obo:GO_0044237, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006412 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002224 ; owl:someValuesFrom obo:GO_0001677 ] . obo:GO_0006414 obo:IAO_0000115 "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." ; oboInOwl:hasAlternativeId "GO:0006442", "GO:0006455" ; oboInOwl:hasBroadSynonym "protein synthesis elongation" ; oboInOwl:hasExactSynonym "translation elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006414" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "translational elongation" ; rdfs:subClassOf obo:GO_0009059, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006412 ] . obo:GO_0006415 obo:IAO_0000115 "The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code)." ; oboInOwl:hasAlternativeId "GO:0006443", "GO:0006456" ; oboInOwl:hasBroadSynonym "protein synthesis termination" ; oboInOwl:hasExactSynonym "translation termination", "translational complex disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006415" ; a owl:Class ; rdfs:label "translational termination" ; rdfs:subClassOf obo:GO_0032984, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006412 ] . obo:GO_0006417 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ; oboInOwl:hasAlternativeId "GO:0006445" ; oboInOwl:hasExactSynonym "regulation of protein anabolism", "regulation of protein biosynthesis", "regulation of protein formation", "regulation of protein synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006417" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of translation" ; rdfs:subClassOf obo:GO_0010556, obo:GO_0010608, obo:GO_0031326, obo:GO_0034248, obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0006446 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of translational initiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006446" ; a owl:Class ; rdfs:label "regulation of translational initiation" ; rdfs:subClassOf obo:GO_0006417, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006413 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006413 ] ) ] . obo:GO_0006448 obo:IAO_0000115 "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006448" ; a owl:Class ; rdfs:label "regulation of translational elongation" ; rdfs:subClassOf obo:GO_0006417, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006414 ] ) ] . obo:GO_0006449 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of translational termination." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006449" ; a owl:Class ; rdfs:label "regulation of translational termination" ; rdfs:subClassOf obo:GO_0006417, obo:GO_0043244, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006415 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006415 ] ) ] . obo:GO_0006468 obo:IAO_0000115 "The process of introducing a phosphate group on to a protein." ; oboInOwl:hasExactSynonym "protein amino acid phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006468" ; oboInOwl:inSubset go:goslim_yeast, go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "protein phosphorylation" ; rdfs:subClassOf obo:GO_0016310, obo:GO_0036211 . obo:GO_0006479 obo:IAO_0000115 "The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom." ; oboInOwl:hasExactSynonym "protein amino acid methylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006479" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "protein methylation" ; rdfs:subClassOf obo:GO_0008213, obo:GO_0043414 . obo:GO_0006516 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ; oboInOwl:hasExactSynonym "glycoprotein breakdown", "glycoprotein catabolism", "glycoprotein degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006516" ; a owl:Class ; rdfs:label "glycoprotein catabolic process" ; rdfs:subClassOf obo:GO_0009100, obo:GO_0030163, obo:GO_1901136, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17089 ] ) ] . obo:GO_0006518 obo:IAO_0000115 "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." ; oboInOwl:hasExactSynonym "peptide metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006518" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "peptide metabolic process" ; rdfs:subClassOf obo:GO_0043603, obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_16670 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0006520 obo:IAO_0000115 "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17904"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006519" ; oboInOwl:hasExactSynonym "cellular amino acid metabolic process", "cellular amino acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "amino acid and derivative metabolism", "cellular amino acid and derivative metabolic process" ; oboInOwl:id "GO:0006520" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "amino acid metabolic process" ; rdfs:subClassOf obo:GO_0019752, obo:GO_0044238, obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_37022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_37022 ] ) ] . obo:GO_0006521 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids." ; oboInOwl:hasExactSynonym "regulation of amino acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006521" ; a owl:Class ; rdfs:label "regulation of cellular amino acid metabolic process" ; rdfs:subClassOf obo:GO_0010565, obo:GO_0033238, obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006520 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006520 ] ) ] . obo:GO_0006576 obo:IAO_0000115 "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ; oboInOwl:hasExactSynonym "biogenic amine metabolism", "cellular biogenic amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006576" ; a owl:Class ; rdfs:label "biogenic amine metabolic process" ; rdfs:subClassOf obo:GO_0009308 . obo:GO_0006581 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline." ; oboInOwl:hasExactSynonym "acetylcholine breakdown", "acetylcholine catabolism", "acetylcholine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006581" ; a owl:Class ; rdfs:label "acetylcholine catabolic process" ; rdfs:subClassOf obo:GO_0008291, obo:GO_0042135, obo:GO_1901575, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15355 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15355 ] ) ] . obo:GO_0006584 obo:IAO_0000115 "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; oboInOwl:hasExactSynonym "catecholamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006584" ; a owl:Class ; rdfs:label "catecholamine metabolic process" ; rdfs:subClassOf obo:GO_0006576, obo:GO_0009712, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33567 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33567 ] ) ] . obo:GO_0006586 obo:IAO_0000115 "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." ; oboInOwl:hasBroadSynonym "indolamine metabolic process", "indolamine metabolism" ; oboInOwl:hasExactSynonym "indolalkylamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006586" ; a owl:Class ; rdfs:label "indolalkylamine metabolic process" ; rdfs:subClassOf obo:GO_0006576, obo:GO_0042430, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_38631 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_38631 ] ) ] . obo:GO_0006611 obo:IAO_0000115 "The directed movement of a protein from the nucleus into the cytoplasm." ; oboInOwl:hasAlternativeId "GO:0097349" ; oboInOwl:hasExactSynonym "protein export from cell nucleus", "protein export out of nucleus", "protein transport from nucleus to cytoplasm", "protein-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "copper-induced protein export from nucleus" ; oboInOwl:id "GO:0006611" ; a owl:Class ; rdfs:label "protein export from nucleus" ; rdfs:subClassOf obo:GO_0006886, obo:GO_0051168 . obo:GO_0006629 obo:IAO_0000115 "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." ; oboInOwl:hasDbXref "Wikipedia:Lipid_metabolism" ; oboInOwl:hasExactSynonym "lipid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006629" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "lipid metabolic process" ; rdfs:subClassOf obo:GO_0044238, obo:GO_0071704, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0006694 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification." ; oboInOwl:hasDbXref "Wikipedia:Steroid_metabolisms#Steroid_biosynthesis" ; oboInOwl:hasExactSynonym "steroid anabolism", "steroid biosynthesis", "steroid formation", "steroid synthesis", "steroidogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006694" ; a owl:Class ; rdfs:label "steroid biosynthetic process" ; rdfs:subClassOf obo:GO_0008202, obo:GO_0008610, obo:GO_1901362, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_35341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_35341 ] ) ] . obo:GO_0006699 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile." ; oboInOwl:hasExactSynonym "bile acid anabolism", "bile acid biosynthesis", "bile acid formation", "bile acid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006699" ; a owl:Class ; rdfs:label "bile acid biosynthetic process" ; rdfs:subClassOf obo:GO_0006694, obo:GO_0008206, obo:GO_0072330, obo:GO_1901617, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_36235 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_36235 ] ) ] . obo:GO_0006706 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ; oboInOwl:hasExactSynonym "steroid breakdown", "steroid catabolism", "steroid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006706" ; a owl:Class ; rdfs:label "steroid catabolic process" ; rdfs:subClassOf obo:GO_0008202, obo:GO_0016042, obo:GO_1901361, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35341 ] ) ] . obo:GO_0006725 obo:IAO_0000115 "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." ; oboInOwl:hasExactSynonym "aromatic compound metabolism" ; oboInOwl:hasNarrowSynonym "aromatic hydrocarbon metabolic process", "aromatic hydrocarbon metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006725" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular aromatic compound metabolic process" ; rdfs:subClassOf obo:GO_0044237, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33655 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33655 ] ) ] . obo:GO_0006790 obo:IAO_0000115 "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." ; oboInOwl:hasDbXref "Wikipedia:Sulfur_metabolism" ; oboInOwl:hasExactSynonym "sulfur metabolism", "sulphur metabolic process", "sulphur metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006790" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "sulfur compound metabolic process" ; rdfs:subClassOf obo:GO_0044237, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_26835 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_26835 ] ) ] . obo:GO_0006793 obo:IAO_0000115 "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." ; oboInOwl:hasExactSynonym "phosphorus metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006793" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "phosphorus metabolic process" ; rdfs:subClassOf obo:GO_0044237, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_26082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_26082 ] ) ] . obo:GO_0006796 obo:IAO_0000115 "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." ; oboInOwl:hasExactSynonym "phosphate metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "phosphate metabolic process" ; oboInOwl:id "GO:0006796" ; a owl:Class ; rdfs:label "phosphate-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006793, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_26020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_26020 ] ) ] . obo:GO_0006807 obo:IAO_0000115 "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen." ; oboInOwl:hasExactSynonym "nitrogen compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006807" ; oboInOwl:inSubset go:goslim_metagenomics, go:goslim_pir ; a owl:Class ; rdfs:label "nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0008152, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_51143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_51143 ] ) ] . obo:GO_0006810 obo:IAO_0000115 "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20292"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-12-13T16:25:32Z" ; oboInOwl:hasAlternativeId "GO:0015457", "GO:0015460", "GO:0044765" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism transport" ; oboInOwl:id "GO:0006810" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ; rdfs:label "transport" ; rdfs:subClassOf obo:GO_0051234 . obo:GO_0006811 obo:IAO_0000115 "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ; oboInOwl:hasBroadSynonym "ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006811" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "monoatomic ion transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24867 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24867 ] ) ] . obo:GO_0006812 obo:IAO_0000115 "The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." ; oboInOwl:hasAlternativeId "GO:0006819", "GO:0015674", "GO:0072512" ; oboInOwl:hasBroadSynonym "cation transport" ; oboInOwl:hasNarrowSynonym "di-, tri-valent inorganic cation transport", "trivalent inorganic cation transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006812" ; a owl:Class ; rdfs:label "monoatomic cation transport" ; rdfs:subClassOf obo:GO_0006811, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_23906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_23906 ] ) ] . obo:GO_0006814 obo:IAO_0000115 "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasAlternativeId "GO:0006834", "GO:0016974" ; oboInOwl:hasBroadSynonym "sodium/potassium transport" ; oboInOwl:hasExactSynonym "sodium transport" ; oboInOwl:hasNarrowSynonym "mitochondrial sodium/calcium ion exchange", "sodium:calcium exchange", "sodium:solute transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "sodium channel auxiliary protein activity" ; oboInOwl:id "GO:0006814" ; a owl:Class ; rdfs:label "sodium ion transport" ; rdfs:subClassOf obo:GO_0030001, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29101 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29101 ] ) ] . obo:GO_0006816 obo:IAO_0000115 "The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "calcium transport" ; oboInOwl:hasNarrowSynonym "mitochondrial sodium/calcium ion exchange", "sodium:calcium exchange" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006816" ; a owl:Class ; rdfs:label "calcium ion transport" ; rdfs:subClassOf obo:GO_0030001, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29108 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29108 ] ) ] . obo:GO_0006817 obo:IAO_0000115 "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "phosphate transport" ; oboInOwl:id "GO:0006817" ; a owl:Class ; rdfs:label "phosphate ion transport" ; rdfs:subClassOf obo:GO_0015698, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35780 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35780 ] ) ] . obo:GO_0006835 obo:IAO_0000115 "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasAlternativeId "GO:0006841" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "sodium:dicarboxylate transport" ; oboInOwl:id "GO:0006835" ; a owl:Class ; rdfs:label "dicarboxylic acid transport" ; rdfs:subClassOf obo:GO_0046942, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35693 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35693 ] ) ] . obo:GO_0006836 obo:IAO_0000115 "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." ; oboInOwl:hasNarrowSynonym "sodium:neurotransmitter transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006836" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "neurotransmitter transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0006837 obo:IAO_0000115 "The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006837" ; a owl:Class ; rdfs:label "serotonin transport" ; rdfs:subClassOf obo:GO_0071705, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_350546 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_350546 ] ) ] . obo:GO_0006846 obo:IAO_0000115 "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006846" ; a owl:Class ; rdfs:label "acetate transport" ; rdfs:subClassOf obo:GO_0015718, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_30089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_30089 ] ) ] . obo:GO_0006847 obo:IAO_0000115 "The directed movement of acetate across a plasma membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006847" ; a owl:Class ; rdfs:label "plasma membrane acetate transport" ; rdfs:subClassOf obo:GO_0035433, [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0005886 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_30089 ] ) ] . obo:GO_0006858 obo:IAO_0000115 "The transport of substances that occurs outside cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006858" ; a owl:Class ; rdfs:label "extracellular transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005576 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005576 ] ) ] . obo:GO_0006860 obo:IAO_0000115 "The directed extracellular movement of amino acids." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006860" ; a owl:Class ; rdfs:label "extracellular amino acid transport" ; rdfs:subClassOf obo:GO_0006858, obo:GO_0006865 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006865 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005576 ] ) ] . obo:GO_0006865 obo:IAO_0000115 "The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasAlternativeId "GO:0006866" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006865" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "amino acid transport" ; rdfs:subClassOf obo:GO_0015849, obo:GO_0071705, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33709 ] ) ] . obo:GO_0006869 obo:IAO_0000115 "The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006869" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "lipid transport" ; rdfs:subClassOf obo:GO_0071702, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010876 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0006873 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "cellular ion homeostasis" ; oboInOwl:hasExactSynonym "cellular monoatomic ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006873" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "intracellular monoatomic ion homeostasis" ; rdfs:subClassOf obo:GO_0050801, obo:GO_0055082 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019725 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_24867 ] ) ] . obo:GO_0006874 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell." ; oboInOwl:hasBroadSynonym "regulation of calcium ion concentration" ; oboInOwl:hasExactSynonym "cellular calcium ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006874" ; a owl:Class ; rdfs:label "intracellular calcium ion homeostasis" ; rdfs:subClassOf obo:GO_0030003, obo:GO_0055074 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019725 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_29108 ] ) ] . obo:GO_0006883 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell." ; oboInOwl:hasExactSynonym "cellular sodium ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006883" ; a owl:Class ; rdfs:label "intracellular sodium ion homeostasis" ; rdfs:subClassOf obo:GO_0030003, obo:GO_0055078 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055082 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_29101 ] ) ] . obo:GO_0006885 obo:IAO_0000115 "Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell." ; oboInOwl:hasExactSynonym "hydrogen ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006885" ; a owl:Class ; rdfs:label "regulation of pH" ; rdfs:subClassOf obo:GO_0055080, obo:GO_0065007 . obo:GO_0006886 obo:IAO_0000115 "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." ; oboInOwl:hasAlternativeId "GO:0032779" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "copper-induced intracellular protein transport" ; oboInOwl:id "GO:0006886" ; oboInOwl:inSubset go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "intracellular protein transport" ; rdfs:subClassOf obo:GO_0015031, obo:GO_0046907, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008104 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0006887 obo:IAO_0000115 "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." ; oboInOwl:hasAlternativeId "GO:0016194", "GO:0016195" ; oboInOwl:hasDbXref "Wikipedia:Exocytosis" ; oboInOwl:hasExactSynonym "vesicle exocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nonselective vesicle exocytosis" ; oboInOwl:id "GO:0006887" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "exocytosis" ; rdfs:subClassOf obo:GO_0016192, obo:GO_0032940, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0099500 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0070382 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0070382 ] ) ] . obo:GO_0006892 obo:IAO_0000115 "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles." ; oboInOwl:hasExactSynonym "post-Golgi transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006892" ; a owl:Class ; rdfs:label "post-Golgi vesicle-mediated transport" ; rdfs:subClassOf obo:GO_0048193 . obo:GO_0006893 obo:IAO_0000115 "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis." ; oboInOwl:hasExactSynonym "Golgi to plasma membrane vesicle-mediated transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006893" ; a owl:Class ; rdfs:label "Golgi to plasma membrane transport" ; rdfs:subClassOf obo:GO_0006892, obo:GO_0098876, [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016192 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0006896 obo:IAO_0000115 "The directed movement of substances from the Golgi to the vacuole." ; oboInOwl:hasExactSynonym "Golgi to vacuole vesicle-mediated transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006896" ; a owl:Class ; rdfs:label "Golgi to vacuole transport" ; rdfs:subClassOf obo:GO_0006892, obo:GO_0007034, [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005794 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0006897 obo:IAO_0000115 "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24907"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/25268"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0016193", "GO:0016196", "GO:0098701" ; oboInOwl:hasDbXref "Wikipedia:Endocytosis" ; oboInOwl:hasExactSynonym "endocytic import into cell", "vesicle endocytosis" ; oboInOwl:hasNarrowSynonym "plasma membrane invagination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nonselective vesicle endocytosis" ; oboInOwl:id "GO:0006897" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "endocytosis" ; rdfs:subClassOf obo:GO_0016192, obo:GO_0098657, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0006900 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0010324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0031410 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0030139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016192 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0030139 ] ) ] . obo:GO_0006898 obo:IAO_0000115 "An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles." ; oboInOwl:hasDbXref "Wikipedia:Receptor-mediated_endocytosis" ; oboInOwl:hasExactSynonym "receptor mediated endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006898" ; a owl:Class ; rdfs:label "receptor-mediated endocytosis" ; rdfs:subClassOf obo:GO_0006897 . obo:GO_0006900 obo:IAO_0000115 "The evagination of a membrane, resulting in formation of a vesicle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-19T15:26:17Z" ; oboInOwl:hasAlternativeId "GO:0006902", "GO:1902591" ; oboInOwl:hasExactSynonym "membrane evagination", "vesicle biosynthesis", "vesicle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nonselective vesicle assembly", "single organism membrane budding", "single-organism membrane budding", "vesicle budding" ; oboInOwl:id "GO:0006900" ; a owl:Class ; rdfs:label "vesicle budding from membrane" ; rdfs:subClassOf obo:GO_0016050, obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016192 ] . obo:GO_0006903 obo:IAO_0000115 "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006903" ; a owl:Class ; rdfs:label "vesicle targeting" ; rdfs:subClassOf obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016192 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051650 ] . obo:GO_0006906 obo:IAO_0000115 "Fusion of the membrane of a transport vesicle with its target membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006906" ; a owl:Class ; rdfs:label "vesicle fusion" ; rdfs:subClassOf obo:GO_0016050, obo:GO_0090174, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016192 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0012506 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0012506 ] ) ] . obo:GO_0006909 obo:IAO_0000115 "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24907"^^xsd:anyURI ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "Wikipedia:Phagocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006909" ; a owl:Class ; rdfs:label "phagocytosis" ; rdfs:subClassOf obo:GO_0006897 . obo:GO_0006910 obo:IAO_0000115 "The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell." ; oboInOwl:hasExactSynonym "recognition of phagocytosed substance by phagocytic cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006910" ; a owl:Class ; rdfs:comment "Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'." ; rdfs:label "phagocytosis, recognition" ; rdfs:subClassOf obo:GO_0008037, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006909 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0038024 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008037 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0006911 obo:IAO_0000115 "The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "phagosome biosynthesis", "phagosome formation" ; oboInOwl:id "GO:0006911" ; a owl:Class ; rdfs:label "phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0099024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099024 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0006913 obo:IAO_0000115 "The directed movement of molecules between the nucleus and the cytoplasm." ; oboInOwl:hasAlternativeId "GO:0000063" ; oboInOwl:hasNarrowSynonym "nucleocytoplasmic shuttling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006913" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pombe ; a owl:Class ; rdfs:comment "Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed." ; rdfs:label "nucleocytoplasmic transport" ; rdfs:subClassOf obo:GO_0051169 . obo:GO_0006914 obo:IAO_0000115 "The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation." ; oboInOwl:hasAlternativeId "GO:0016238" ; oboInOwl:hasDbXref "Wikipedia:Autophagy_(cellular)" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006914" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe ; a owl:Class ; rdfs:label "autophagy" ; rdfs:subClassOf obo:GO_0044248, obo:GO_0061919, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002230 ; owl:someValuesFrom obo:GO_0055085 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0006915 obo:IAO_0000115 "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." ; obo:RO_0002161 obo:NCBITaxon_2, obo:NCBITaxon_4896 ; oboInOwl:hasAlternativeId "GO:0006917", "GO:0008632" ; oboInOwl:hasBroadSynonym "cell suicide", "cellular suicide" ; oboInOwl:hasDbXref "Wikipedia:Apoptosis" ; oboInOwl:hasExactSynonym "apoptotic cell death", "apoptotic programmed cell death", "programmed cell death by apoptosis" ; oboInOwl:hasNarrowSynonym "activation of apoptosis", "apoptosis", "apoptosis signaling", "apoptotic program", "type I programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "apoptosis activator activity", "caspase-dependent programmed cell death", "commitment to apoptosis", "induction of apoptosis", "induction of apoptosis by p53", "signaling (initiator) caspase activity" ; oboInOwl:id "GO:0006915" ; a owl:Class ; rdfs:label "apoptotic process" ; rdfs:subClassOf obo:GO_0012501, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_2 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4896 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33154 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_2 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4896 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002224 ; owl:someValuesFrom obo:GO_0097190 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002230 ; owl:someValuesFrom obo:GO_0097194 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33154 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_2 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4896 ] . obo:GO_0006921 obo:IAO_0000115 "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis." ; oboInOwl:hasBroadSynonym "cellular component disassembly involved in apoptotic process", "disassembly of cell structures" ; oboInOwl:hasNarrowSynonym "cellular component disassembly involved in apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006921" ; a owl:Class ; rdfs:label "cellular component disassembly involved in execution phase of apoptosis" ; rdfs:subClassOf obo:GO_0022411, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0097194 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0097194 ] ) ] . obo:GO_0006935 obo:IAO_0000115 "The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ; oboInOwl:hasDbXref "Wikipedia:Chemotaxis" ; oboInOwl:hasExactSynonym "taxis in response to chemical stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006935" ; a owl:Class ; rdfs:label "chemotaxis" ; rdfs:subClassOf obo:GO_0042330, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042221 ] . obo:GO_0006936 obo:IAO_0000115 "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." ; oboInOwl:hasDbXref "Wikipedia:Muscle_contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006936" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "muscle contraction" ; rdfs:subClassOf obo:GO_0003012, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002385 ] . obo:GO_0006937 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of muscle contraction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006937" ; a owl:Class ; rdfs:label "regulation of muscle contraction" ; rdfs:subClassOf obo:GO_0090257, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006936 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006936 ] ) ] . obo:GO_0006939 obo:IAO_0000115 "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length." ; oboInOwl:hasExactSynonym "visceral muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006939" ; a owl:Class ; rdfs:label "smooth muscle contraction" ; rdfs:subClassOf obo:GO_0006936, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001135 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006936 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001135 ] ) ] . obo:GO_0006940 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of smooth muscle contraction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006940" ; a owl:Class ; rdfs:label "regulation of smooth muscle contraction" ; rdfs:subClassOf obo:GO_0006937, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006939 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006939 ] ) ] . obo:GO_0006941 obo:IAO_0000115 "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope." ; oboInOwl:hasExactSynonym "sarcomeric muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006941" ; a owl:Class ; rdfs:label "striated muscle contraction" ; rdfs:subClassOf obo:GO_0006936, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002036 ] . obo:GO_0006942 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of striated muscle contraction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006942" ; a owl:Class ; rdfs:label "regulation of striated muscle contraction" ; rdfs:subClassOf obo:GO_0006937, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006941 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006941 ] ) ] . obo:GO_0006949 obo:IAO_0000115 "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006949" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "syncytium formation" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:CL_0000228 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:CL_0000228 ] ) ] . obo:GO_0006950 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to abiotic stress", "response to biotic stress" ; oboInOwl:id "GO:0006950" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to stress" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0006952 obo:IAO_0000115 "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." ; oboInOwl:hasAlternativeId "GO:0002217", "GO:0042829" ; oboInOwl:hasExactSynonym "defence response", "physiological defense response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "antimicrobial peptide activity", "defense/immunity protein activity" ; oboInOwl:id "GO:0006952" ; a owl:Class ; rdfs:label "defense response" ; rdfs:subClassOf obo:GO_0006950 . obo:GO_0006954 obo:IAO_0000115 "The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages." ; oboInOwl:hasBroadSynonym "inflammation" ; oboInOwl:hasDbXref "Wikipedia:Inflammation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006954" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "inflammatory response" ; rdfs:subClassOf obo:GO_0006952, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0006955 obo:IAO_0000115 "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006955" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "immune response" ; rdfs:subClassOf obo:GO_0002376, obo:GO_0050896 . obo:GO_0006970 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:hasExactSynonym "osmotic response", "osmotic stress response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006970" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "response to osmotic stress" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0009628 . obo:GO_0006974 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24775"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0034984" ; oboInOwl:hasBroadSynonym "response to DNA damage stimulus" ; oboInOwl:hasExactSynonym "cellular DNA damage response", "cellular response to DNA damage stimulus", "response to genotoxic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006974" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "DNA damage response" ; rdfs:subClassOf obo:GO_0033554 . obo:GO_0006979 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006979" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "response to oxidative stress" ; rdfs:subClassOf obo:GO_0006950 . obo:GO_0006983 obo:IAO_0000115 "The series of molecular signals initiated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB." ; oboInOwl:hasAlternativeId "GO:0006985" ; oboInOwl:hasExactSynonym "EOR", "ER-overload response", "endoplasmic reticulum overload response" ; oboInOwl:hasNarrowSynonym "EOR-mediated NF-kappaB activation", "EOR-mediated activation of NF-kappaB", "positive regulation of NF-kappaB transcription factor activity by EOR", "positive regulation of NF-kappaB transcription factor activity by ER overload response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006983" ; a owl:Class ; rdfs:label "ER overload response" ; rdfs:subClassOf obo:GO_0006984, obo:GO_0034976, obo:GO_0071216 . obo:GO_0006984 obo:IAO_0000115 "The series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation." ; oboInOwl:hasExactSynonym "ER to nucleus signaling pathway", "ER to nucleus signalling pathway", "ER-nuclear signaling pathway", "ER-nuclear signalling pathway", "endoplasmic reticulum to nucleus signaling pathway", "endoplasmic reticulum-nuclear signaling pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006984" ; a owl:Class ; rdfs:label "ER-nucleus signaling pathway" ; rdfs:subClassOf obo:GO_0007165 . obo:GO_0006986 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heat shock protein activity" ; oboInOwl:id "GO:0006986" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to one specific response to the presence of unfolded proteins in the ER." ; rdfs:label "response to unfolded protein" ; rdfs:subClassOf obo:GO_0035966 . obo:GO_0006990 obo:IAO_0000115 "The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response." ; oboInOwl:hasBroadSynonym "unfolded protein response, target gene transcriptional activation" ; oboInOwl:hasExactSynonym "positive regulation of transcription of target genes involved in unfolded protein response", "unfolded protein response, positive regulation of target gene transcription", "unfolded protein response, up regulation of target gene transcription", "unfolded protein response, up-regulation of target gene transcription", "unfolded protein response, upregulation of target gene transcription" ; oboInOwl:hasNarrowSynonym "unfolded protein response, activation of target gene transcription", "unfolded protein response, stimulation of target gene transcription" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006990" ; a owl:Class ; rdfs:label "positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response" ; rdfs:subClassOf obo:GO_1901522, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030968 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045944 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030968 ] ) ] . obo:GO_0006996 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-19T15:25:51Z" ; oboInOwl:hasAlternativeId "GO:1902589" ; oboInOwl:hasExactSynonym "organelle organisation", "single organism organelle organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "organelle organization and biogenesis", "single-organism organelle organization" ; oboInOwl:id "GO:0006996" ; oboInOwl:inSubset go:goslim_candida, go:goslim_pir ; a owl:Class ; rdfs:label "organelle organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0006997 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." ; oboInOwl:hasAlternativeId "GO:0048287" ; oboInOwl:hasExactSynonym "nuclear organisation", "nuclear organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear morphology", "nuclear organization and biogenesis", "nucleus organization and biogenesis" ; oboInOwl:id "GO:0006997" ; oboInOwl:inSubset go:goslim_candida, go:goslim_drosophila, go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "nucleus organization" ; rdfs:subClassOf obo:GO_0006996, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0006998 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." ; oboInOwl:hasExactSynonym "nuclear envelope organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear envelope organization and biogenesis" ; oboInOwl:id "GO:0006998" ; a owl:Class ; rdfs:label "nuclear envelope organization" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006997 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010256 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005635 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005635 ] ) ] . obo:GO_0007000 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus." ; oboInOwl:hasExactSynonym "nucleolus organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nucleolus organization and biogenesis" ; oboInOwl:id "GO:0007000" ; a owl:Class ; rdfs:label "nucleolus organization" ; rdfs:subClassOf obo:GO_0006997, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005730 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005730 ] ) ] . obo:GO_0007005 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components." ; oboInOwl:hasExactSynonym "mitochondria organization", "mitochondrion organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitochondrion organization and biogenesis" ; oboInOwl:id "GO:0007005" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:label "mitochondrion organization" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0007006 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion." ; oboInOwl:hasExactSynonym "mitochondrial membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitochondrial membrane organization and biogenesis" ; oboInOwl:id "GO:0007006" ; a owl:Class ; rdfs:label "mitochondrial membrane organization" ; rdfs:subClassOf obo:GO_0007005, obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061024 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0007009 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." ; oboInOwl:hasExactSynonym "plasma membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "plasma membrane organization and biogenesis" ; oboInOwl:id "GO:0007009" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "plasma membrane organization" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010256 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0007010 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." ; oboInOwl:hasExactSynonym "cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cytoskeletal organization and biogenesis", "cytoskeletal regulator activity", "cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0007010" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "cytoskeleton organization" ; rdfs:subClassOf obo:GO_0006996, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005856 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005856 ] ) ] . obo:GO_0007015 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking." ; oboInOwl:hasExactSynonym "actin filament organisation" ; oboInOwl:hasNarrowSynonym "regulation of actin filament localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007015" ; a owl:Class ; rdfs:label "actin filament organization" ; rdfs:subClassOf obo:GO_0097435, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030036 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005884 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005884 ] ) ] . obo:GO_0007017 obo:IAO_0000115 "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007017" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "microtubule-based process" ; rdfs:subClassOf obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0005874 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0007018 obo:IAO_0000115 "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007018" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic ; a owl:Class ; rdfs:label "microtubule-based movement" ; rdfs:subClassOf obo:GO_0007017 . obo:GO_0007019 obo:IAO_0000115 "The removal of tubulin heterodimers from one or both ends of a microtubule." ; oboInOwl:hasExactSynonym "microtubule disassembly", "microtubule shortening" ; oboInOwl:hasNarrowSynonym "microtubule catastrophe", "microtubule depolymerization during nuclear congression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007019" ; a owl:Class ; rdfs:label "microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031109, obo:GO_0051261, obo:GO_0097435, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005874 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0007020 obo:IAO_0000115 "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." ; oboInOwl:hasDbXref "Wikipedia:Microtubule_nucleation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007020" ; a owl:Class ; rdfs:label "microtubule nucleation" ; rdfs:subClassOf obo:GO_0000226, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046785 ] . obo:GO_0007026 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." ; oboInOwl:hasExactSynonym "down regulation of microtubule depolymerization", "down-regulation of microtubule depolymerization", "downregulation of microtubule depolymerization", "microtubule stabilization", "negative regulation of microtubule disassembly" ; oboInOwl:hasNarrowSynonym "inhibition of microtubule depolymerization", "microtubule rescue", "negative regulation of microtubule catastrophe" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007026" ; a owl:Class ; rdfs:label "negative regulation of microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031111, obo:GO_0031114, obo:GO_1901880, obo:GO_1902904, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007019 ] ) ] . obo:GO_0007027 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." ; oboInOwl:hasExactSynonym "axonemal microtubule stabilization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of microtubule depolymerization in axoneme" ; oboInOwl:id "GO:0007027" ; a owl:Class ; rdfs:label "negative regulation of axonemal microtubule depolymerization" ; rdfs:subClassOf obo:GO_0007026, obo:GO_0010937, obo:GO_0031345, obo:GO_0120035, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060404 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060404 ] ) ] . obo:GO_0007028 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." ; oboInOwl:hasExactSynonym "cytoplasm organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cytoplasm organization and biogenesis" ; oboInOwl:id "GO:0007028" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cytoplasm organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0007030 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus." ; oboInOwl:hasExactSynonym "Golgi apparatus organization", "Golgi organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "Golgi organization and biogenesis" ; oboInOwl:id "GO:0007030" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "Golgi organization" ; rdfs:subClassOf obo:GO_0006996, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010256 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005794 ] ) ] . obo:GO_0007031 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." ; oboInOwl:hasExactSynonym "peroxisome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "peroxisome organization and biogenesis", "peroxisome-assembly ATPase activity" ; oboInOwl:id "GO:0007031" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:label "peroxisome organization" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0007033 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." ; oboInOwl:hasAlternativeId "GO:0044086" ; oboInOwl:hasExactSynonym "vacuole organisation" ; oboInOwl:hasNarrowSynonym "vacuolar assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "vacuole biogenesis", "vacuole organization and biogenesis" ; oboInOwl:id "GO:0007033" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "vacuole organization" ; rdfs:subClassOf obo:GO_0006996, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0007034 obo:IAO_0000115 "The directed movement of substances into, out of or within a vacuole." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007034" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "vacuolar transport" ; rdfs:subClassOf obo:GO_0046907, [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0007036 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007036" ; a owl:Class ; rdfs:label "vacuolar calcium ion homeostasis" ; rdfs:subClassOf obo:GO_0006874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055074 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0007039 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "vacuolar protein breakdown", "vacuolar protein catabolic process", "vacuolar protein catabolism", "vacuolar protein degradation" ; oboInOwl:id "GO:0007039" ; a owl:Class ; rdfs:label "protein catabolic process in the vacuole" ; rdfs:subClassOf obo:GO_0030163, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030163 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0007040 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases." ; oboInOwl:hasExactSynonym "lysosome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lysosome organization and biogenesis" ; oboInOwl:id "GO:0007040" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "lysosome organization" ; rdfs:subClassOf obo:GO_0080171, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005764 ] ) ] . obo:GO_0007041 obo:IAO_0000115 "The directed movement of substances into, out of or within a lysosome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007041" ; a owl:Class ; rdfs:label "lysosomal transport" ; rdfs:subClassOf obo:GO_0007034, [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005764 ] ) ] . obo:GO_0007043 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a junction between cells." ; oboInOwl:hasExactSynonym "intercellular junction assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007043" ; a owl:Class ; rdfs:label "cell-cell junction assembly" ; rdfs:subClassOf obo:GO_0034329, obo:GO_0045216, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0034329 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005911 ] ) ] . obo:GO_0007049 obo:IAO_0000115 "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." ; oboInOwl:hasDbXref "Wikipedia:Cell_cycle" ; oboInOwl:hasExactSynonym "cell-division cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007049" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "cell cycle" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0007051 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart." ; oboInOwl:hasAlternativeId "GO:0043146" ; oboInOwl:hasExactSynonym "spindle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "spindle organization and biogenesis", "spindle stabilization" ; oboInOwl:id "GO:0007051" ; a owl:Class ; rdfs:label "spindle organization" ; rdfs:subClassOf obo:GO_0000226, obo:GO_0022402 . obo:GO_0007052 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/15341"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0000071", "GO:0030472", "GO:0043148" ; oboInOwl:hasExactSynonym "mitotic spindle organisation", "spindle organization and biogenesis during mitosis" ; oboInOwl:hasNarrowSynonym "mitotic spindle organisation in nucleus", "mitotic spindle organization and biogenesis in cell nucleus", "mitotic spindle organization and biogenesis in nucleus", "mitotic spindle organization in nucleus", "spindle organization and biogenesis in nucleus during mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic spindle organization and biogenesis", "mitotic spindle stabilization" ; oboInOwl:id "GO:0007052" ; a owl:Class ; rdfs:comment "In fission yeast most mitotic spindle organization occurs in the nucleus." ; rdfs:label "mitotic spindle organization" ; rdfs:subClassOf obo:GO_0007051, obo:GO_1902850 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007051 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007053 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007053" ; a owl:Class ; rdfs:label "spindle assembly involved in male meiosis" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0090306, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ) ] . obo:GO_0007054 obo:IAO_0000115 "The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "male meiosis I spindle assembly" ; oboInOwl:id "GO:0007054" ; a owl:Class ; rdfs:label "spindle assembly involved in male meiosis I" ; rdfs:subClassOf obo:GO_0007053, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007141 ] ) ] . obo:GO_0007056 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "female meiotic spindle assembly" ; oboInOwl:id "GO:0007056" ; a owl:Class ; rdfs:label "spindle assembly involved in female meiosis" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0090306, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ) ] . obo:GO_0007057 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "female meiosis I spindle assembly" ; oboInOwl:id "GO:0007057" ; a owl:Class ; rdfs:label "spindle assembly involved in female meiosis I" ; rdfs:subClassOf obo:GO_0007056, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007144 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007144 ] ) ] . obo:GO_0007059 obo:IAO_0000115 "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." ; oboInOwl:hasDbXref "Wikipedia:Chromosome_segregation" ; oboInOwl:hasExactSynonym "chromosome division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosome transmission" ; oboInOwl:id "GO:0007059" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "chromosome segregation" ; rdfs:subClassOf obo:GO_0022402 . obo:GO_0007060 obo:IAO_0000115 "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007060" ; a owl:Class ; rdfs:label "male meiosis chromosome segregation" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0045132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] . obo:GO_0007076 obo:IAO_0000115 "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007076" ; a owl:Class ; rdfs:label "mitotic chromosome condensation" ; rdfs:subClassOf obo:GO_0030261, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030261 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007077 obo:IAO_0000115 "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis." ; oboInOwl:hasBroadSynonym "NEB", "local NEB", "nuclear envelope breakdown" ; oboInOwl:hasExactSynonym "mitotic nuclear envelope breakdown" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic nuclear envelope catabolism", "mitotic nuclear envelope degradation", "mitotic nuclear envelope disassembly" ; oboInOwl:id "GO:0007077" ; a owl:Class ; rdfs:label "mitotic nuclear membrane disassembly" ; rdfs:subClassOf obo:GO_0051081, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051081 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007080 obo:IAO_0000115 "The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007080" ; a owl:Class ; rdfs:label "mitotic metaphase plate congression" ; rdfs:subClassOf obo:GO_0051310, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051310 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007084 obo:IAO_0000115 "The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19950"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/20636"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "nuclear envelope repair", "nuclear envelope resealing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic nuclear envelope reassembly" ; oboInOwl:id "GO:0007084" ; a owl:Class ; rdfs:label "mitotic nuclear membrane reassembly" ; rdfs:subClassOf obo:GO_0031468, obo:GO_0101024 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031468 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007088 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitosis." ; oboInOwl:hasExactSynonym "regulation of mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007088" ; a owl:Class ; rdfs:label "regulation of mitotic nuclear division" ; rdfs:subClassOf obo:GO_0007346, obo:GO_0010564, obo:GO_0051783, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0007091 obo:IAO_0000115 "The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24140"^^xsd:anyURI ; oboInOwl:hasExactSynonym "metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process", "mitotic metaphase/anaphase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007091" ; a owl:Class ; rdfs:label "metaphase/anaphase transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0044772, obo:GO_0044784 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044784 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007093 obo:IAO_0000115 "A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0031575", "GO:0071780", "GO:0072413", "GO:0072456", "GO:0072474" ; oboInOwl:hasExactSynonym "mitotic cell cycle checkpoint", "signal transduction involved in mitotic cell cycle checkpoint" ; oboInOwl:hasNarrowSynonym "signal transduction involved in mitotic G2/M transition checkpoint", "signal transduction involved in mitotic cell cycle G1/S checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic checkpoint" ; oboInOwl:id "GO:0007093" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "mitotic cell cycle checkpoint signaling" ; rdfs:subClassOf obo:GO_0000075, obo:GO_0045930, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000075 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007094 obo:IAO_0000115 "A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signalling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19810"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/24179"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0044810", "GO:0072480", "GO:1902420" ; oboInOwl:hasExactSynonym "mitotic cell cycle spindle assembly checkpoint", "mitotic checkpoint", "mitotic spindle assembly checkpoint", "mitotic spindle assembly checkpoint signalling", "signal transduction involved in mitotic cell cycle spindle assembly checkpoint", "signal transduction involved in mitotic spindle assembly checkpoint" ; oboInOwl:hasNarrowSynonym "Dma1-dependent checkpoint", "Mad2-dependent checkpoint", "SAC-independent checkpoint", "signal transduction involved in Dma1-dependent checkpoint", "signal transduction involved in SAC-independent checkpoint", "signaling cascade involved in Dma1-dependent checkpoint", "signaling cascade involved in SAC-independent checkpoint", "signalling cascade involved in Dma1-dependent checkpoint", "signalling cascade involved in SAC-independent checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "signaling pathway involved in Dma1-dependent checkpoint", "signaling pathway involved in SAC-independent checkpoint", "signalling pathway involved in Dma1-dependent checkpoint", "signalling pathway involved in SAC-independent checkpoint" ; oboInOwl:id "GO:0007094" ; a owl:Class ; rdfs:label "mitotic spindle assembly checkpoint signaling" ; rdfs:subClassOf obo:GO_0045841, obo:GO_0071173, obo:GO_0071174 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071173 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007097 obo:IAO_0000115 "The directed movement of the nucleus to a specific location within a cell." ; oboInOwl:hasAlternativeId "GO:0040023" ; oboInOwl:hasExactSynonym "establishment of position of nucleus", "nuclear movement", "nuclear positioning", "nucleus migration", "nucleus positioning", "positioning of nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "establishment of cell nucleus localization", "establishment of localization of nucleus", "establishment of nucleus localisation", "establishment of nucleus localization" ; oboInOwl:id "GO:0007097" ; a owl:Class ; rdfs:label "nuclear migration" ; rdfs:subClassOf obo:GO_0046907, obo:GO_0051647, obo:GO_0051656 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0007112 obo:IAO_0000115 "A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells." ; oboInOwl:hasExactSynonym "cytokinesis after male meiosis", "cytokinesis involved in male meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007112" ; a owl:Class ; rdfs:label "male meiosis cytokinesis" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0033206, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000910 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ) ] . obo:GO_0007113 obo:IAO_0000115 "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell." ; oboInOwl:hasDbXref "Wikipedia:Mitosis#Endomitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "endomitosis" ; oboInOwl:id "GO:0007113" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins." ; rdfs:label "endomitotic cell cycle" ; rdfs:subClassOf obo:GO_0000278 . obo:GO_0007127 obo:IAO_0000115 "The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei." ; oboInOwl:hasDbXref "Wikipedia:Meiosis#Meiosis_I" ; oboInOwl:hasExactSynonym "meiosis I nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007127" ; a owl:Class ; rdfs:label "meiosis I" ; rdfs:subClassOf obo:GO_0061982, obo:GO_0140013, [ a owl:Restriction ; owl:onProperty obo:RO_0002093 ; owl:someValuesFrom obo:GO_0007134 ] . obo:GO_0007129 obo:IAO_0000115 "The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete." ; oboInOwl:hasDbXref "Wikipedia:Synapsis" ; oboInOwl:hasNarrowSynonym "chromosomal synapsis", "synapsis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosomal pairing" ; oboInOwl:id "GO:0007129" ; a owl:Class ; rdfs:label "homologous chromosome pairing at meiosis" ; rdfs:subClassOf obo:GO_0070192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045143 ] . obo:GO_0007134 obo:IAO_0000115 "The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007134" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiotic telophase I" ; rdfs:subClassOf obo:GO_0051326, obo:GO_0098764 . obo:GO_0007135 obo:IAO_0000115 "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II." ; oboInOwl:hasDbXref "Wikipedia:Meiosis#Meiosis_II" ; oboInOwl:hasExactSynonym "meiosis II nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007135" ; a owl:Class ; rdfs:label "meiosis II" ; rdfs:subClassOf obo:GO_0061983, obo:GO_0140013 . obo:GO_0007140 obo:IAO_0000115 "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasBroadSynonym "male nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "male meiosis" ; oboInOwl:id "GO:0007140" ; a owl:Class ; rdfs:label "male meiotic nuclear division" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0140013, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048232 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000280 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048232 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007141 obo:IAO_0000115 "A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline." ; oboInOwl:hasExactSynonym "male meiosis I nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007141" ; a owl:Class ; rdfs:label "male meiosis I" ; rdfs:subClassOf obo:GO_0007127, obo:GO_0007140 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007127 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048232 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007142 obo:IAO_0000115 "A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline." ; oboInOwl:hasExactSynonym "male meiosis II nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007142" ; a owl:Class ; rdfs:label "male meiosis II" ; rdfs:subClassOf obo:GO_0007135, obo:GO_0007140 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007135 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048232 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007143 obo:IAO_0000115 "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasBroadSynonym "female meiosis", "female meiotic division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007143" ; a owl:Class ; rdfs:comment "Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'." ; rdfs:label "female meiotic nuclear division" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0140013, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000280 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007144 obo:IAO_0000115 "The cell cycle process in which the first meiotic division occurs in the female germline." ; oboInOwl:hasExactSynonym "female meiosis I nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007144" ; a owl:Class ; rdfs:label "female meiosis I" ; rdfs:subClassOf obo:GO_0007127, obo:GO_0007143 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007127 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007147 obo:IAO_0000115 "The cell cycle process in which the second meiotic division occurs in the female germline." ; oboInOwl:hasExactSynonym "female meiosis II nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007147" ; a owl:Class ; rdfs:label "female meiosis II" ; rdfs:subClassOf obo:GO_0007135, obo:GO_0007143 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007135 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007154 obo:IAO_0000115 "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:hasDbXref "Wikipedia:Cell_signaling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007154" ; oboInOwl:inSubset go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "cell communication" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0007155 obo:IAO_0000115 "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2014-04-15T15:59:10Z" ; oboInOwl:hasAlternativeId "GO:0098602" ; oboInOwl:hasDbXref "Wikipedia:Cell_adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell adhesion molecule activity", "single organism cell adhesion" ; oboInOwl:id "GO:0007155" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "cell adhesion" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0007159 obo:IAO_0000115 "The attachment of a leukocyte to another cell via adhesion molecules." ; obo:RO_0002161 obo:NCBITaxon_33090 ; oboInOwl:hasExactSynonym "leukocyte adhesion", "leukocyte cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007159" ; a owl:Class ; rdfs:label "leukocyte cell-cell adhesion" ; rdfs:subClassOf obo:GO_0098609, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_33090 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:CL_0000738 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_33090 ] ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_33090 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098609 [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0007162 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." ; oboInOwl:hasExactSynonym "down regulation of cell adhesion", "down-regulation of cell adhesion", "downregulation of cell adhesion" ; oboInOwl:hasNarrowSynonym "inhibition of cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell adhesion receptor inhibitor activity" ; oboInOwl:id "GO:0007162" ; a owl:Class ; rdfs:label "negative regulation of cell adhesion" ; rdfs:subClassOf obo:GO_0030155, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007155 ] ) ] . obo:GO_0007163 obo:IAO_0000115 "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." ; oboInOwl:hasAlternativeId "GO:0030012", "GO:0030467" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell polarity", "establishment and/or maintenance of cell polarity", "establishment and/or maintenance of cell polarization" ; oboInOwl:id "GO:0007163" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "establishment or maintenance of cell polarity" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0007165 obo:IAO_0000115 "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." ; oboInOwl:hasAlternativeId "GO:0023014", "GO:0023015", "GO:0023016", "GO:0023033", "GO:0023045" ; oboInOwl:hasDbXref "Wikipedia:Signal_transduction" ; oboInOwl:hasNarrowSynonym "signal transduction by cis-phosphorylation", "signal transduction by conformational transition", "signal transduction by protein phosphorylation", "signal transduction by trans-phosphorylation", "signaling cascade", "signalling cascade" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "signaling pathway", "signalling pathway" ; oboInOwl:id "GO:0007165" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not." ; rdfs:label "signal transduction" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007154 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0023052 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051716 ] . obo:GO_0007267 obo:IAO_0000115 "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." ; oboInOwl:hasExactSynonym "cell-cell signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007267" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_plant ; a owl:Class ; rdfs:label "cell-cell signaling" ; rdfs:subClassOf obo:GO_0007154, obo:GO_0023052 . obo:GO_0007268 obo:IAO_0000115 "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; oboInOwl:hasBroadSynonym "signal transmission across a synapse", "synaptic transmission" ; oboInOwl:hasDbXref "Wikipedia:Neurotransmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neurotransmission" ; oboInOwl:id "GO:0007268" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "chemical synaptic transmission" ; rdfs:subClassOf obo:GO_0098916, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:GO_0045202 ] . obo:GO_0007269 obo:IAO_0000115 "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." ; oboInOwl:hasAlternativeId "GO:0010554" ; oboInOwl:hasExactSynonym "neurotransmitter release", "neurotransmitter secretory pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007269" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." ; rdfs:label "neurotransmitter secretion" ; rdfs:subClassOf obo:GO_0001505, obo:GO_0006836, obo:GO_0051649, obo:GO_0099643, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007268 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] . obo:GO_0007271 obo:IAO_0000115 "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; oboInOwl:hasExactSynonym "cholinergic synaptic transmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007271" ; a owl:Class ; rdfs:label "synaptic transmission, cholinergic" ; rdfs:subClassOf obo:GO_0007268, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:CHEBI_15355 ] . obo:GO_0007274 obo:IAO_0000115 "The process of synaptic transmission from a neuron to a muscle, across a synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007274" ; a owl:Class ; rdfs:label "neuromuscular synaptic transmission" ; rdfs:subClassOf obo:GO_0007268 . obo:GO_0007275 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21234"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007275" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_chembl, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term was 'developmental process'." ; rdfs:label "multicellular organism development" ; rdfs:subClassOf obo:GO_0032501, obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:UBERON_0000468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:UBERON_0000468 ] ) ] . obo:GO_0007276 obo:IAO_0000115 "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." ; obo:RO_0002161 obo:NCBITaxon_Union_0000023 ; oboInOwl:hasAlternativeId "GO:0009552" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "gametogenesis" ; oboInOwl:id "GO:0007276" ; a owl:Class ; rdfs:label "gamete generation" ; rdfs:subClassOf obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019953 ] . obo:GO_0007281 obo:IAO_0000115 "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." ; oboInOwl:hasExactSynonym "germ-cell development" ; oboInOwl:hasNarrowSynonym "primordial germ cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007281" ; a owl:Class ; rdfs:label "germ cell development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007276 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000586 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000586 ] ) ] . obo:GO_0007283 obo:IAO_0000115 "The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa." ; oboInOwl:hasDbXref "Wikipedia:Spermatogenesis" ; oboInOwl:hasExactSynonym "generation of spermatozoa" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007283" ; a owl:Class ; rdfs:label "spermatogenesis" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0048232 . obo:GO_0007284 obo:IAO_0000115 "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes)." ; oboInOwl:hasExactSynonym "spermatogonium division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007284" ; a owl:Class ; rdfs:comment "See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'." ; rdfs:label "spermatogonial cell division" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0051301, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007283 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051301 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000020 ] ) ] . obo:GO_0007285 obo:IAO_0000115 "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007285" ; a owl:Class ; rdfs:label "primary spermatocyte growth" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0048588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007283 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:CL_0000656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040007 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:CL_0000656 ] ) ] . obo:GO_0007286 obo:IAO_0000115 "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." ; oboInOwl:hasDbXref "Wikipedia:Spermiogenesis" ; oboInOwl:hasExactSynonym "spermatid cell development", "spermiogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007286" ; a owl:Class ; rdfs:label "spermatid development" ; rdfs:subClassOf obo:GO_0007281, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048515 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000018 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000018 ] ) ] . obo:GO_0007288 obo:IAO_0000115 "The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007288" ; a owl:Class ; rdfs:label "sperm axoneme assembly" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0035082, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0120316 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0035082 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000019 ] ) ] . obo:GO_0007289 obo:IAO_0000115 "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization." ; oboInOwl:hasExactSynonym "spermatid nuclear differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007289" ; a owl:Class ; rdfs:comment "See also the Cell Ontology term 'spermatid ; CL:0000018'." ; rdfs:label "spermatid nucleus differentiation" ; rdfs:subClassOf obo:GO_0006997, obo:GO_0022412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007286 ] . obo:GO_0007292 obo:IAO_0000115 "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007292" ; a owl:Class ; rdfs:label "female gamete generation" ; rdfs:subClassOf obo:GO_0007276 . obo:GO_0007293 obo:IAO_0000115 "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007293" ; a owl:Class ; rdfs:label "germarium-derived egg chamber formation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048477 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_6656 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_6656 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0007296 obo:IAO_0000115 "The production of yolk. Yolk is a mixture of materials used for embryonic nutrition." ; oboInOwl:hasDbXref "Wikipedia:Vitellogenesis" ; oboInOwl:hasExactSynonym "yolk formation", "yolk production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007296" ; a owl:Class ; rdfs:label "vitellogenesis" ; rdfs:subClassOf obo:GO_0007028, obo:GO_0022412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] . obo:GO_0007308 obo:IAO_0000115 "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0048110" ; oboInOwl:hasExactSynonym "oocyte arrangement" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007308" ; a owl:Class ; rdfs:label "oocyte construction" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0048469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048599 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:CL_0000023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:CL_0000023 ] ) ] . obo:GO_0007309 obo:IAO_0000115 "The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0048111" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "oocyte axis determination" ; oboInOwl:id "GO:0007309" ; a owl:Class ; rdfs:label "oocyte axis specification" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0009798, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007308 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009798 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000023 ] ) ] . obo:GO_0007314 obo:IAO_0000115 "Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0048112" ; oboInOwl:hasExactSynonym "oocyte anterior/posterior axis determination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007314" ; a owl:Class ; rdfs:label "oocyte anterior/posterior axis specification" ; rdfs:subClassOf obo:GO_0007309, obo:GO_0009948, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008358 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009948 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000023 ] ) ] . obo:GO_0007320 obo:IAO_0000115 "The introduction of semen or sperm into the genital tract of a female." ; oboInOwl:hasDbXref "Wikipedia:Insemination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007320" ; a owl:Class ; rdfs:label "insemination" ; rdfs:subClassOf obo:GO_0044703, obo:GO_0044706, obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007620 ] . obo:GO_0007338 obo:IAO_0000115 "The union of male and female gametes to form a zygote." ; obo:RO_0002161 obo:NCBITaxon_58024 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "zygote biosynthesis", "zygote formation" ; oboInOwl:id "GO:0007338" ; a owl:Class ; rdfs:label "single fertilization" ; rdfs:subClassOf obo:GO_0009566, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_58024 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_58024 ] ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_58024 ] . obo:GO_0007343 obo:IAO_0000115 "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm." ; oboInOwl:hasDbXref "Wikipedia:Egg_activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007343" ; a owl:Class ; rdfs:label "egg activation" ; rdfs:subClassOf obo:GO_0001775, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007338 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000025 ] ) ] . obo:GO_0007346 obo:IAO_0000115 "Any process that modulates the rate or extent of progress through the mitotic cell cycle." ; oboInOwl:hasExactSynonym "mitotic cell cycle modulation", "mitotic cell cycle regulation", "modulation of mitotic cell cycle progression", "regulation of mitotic cell cycle progression", "regulation of progression through mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic cell cycle regulator" ; oboInOwl:id "GO:0007346" ; a owl:Class ; rdfs:label "regulation of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0051726, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007350 obo:IAO_0000115 "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007350" ; a owl:Class ; rdfs:label "blastoderm segmentation" ; rdfs:subClassOf obo:GO_0009880, obo:GO_0035282 . obo:GO_0007351 obo:IAO_0000115 "Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007351" ; a owl:Class ; rdfs:label "tripartite regional subdivision" ; rdfs:subClassOf obo:GO_0003002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007350 ] . obo:GO_0007354 obo:IAO_0000115 "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007354" ; a owl:Class ; rdfs:label "zygotic determination of anterior/posterior axis, embryo" ; rdfs:subClassOf obo:GO_0008595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008595 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000365 ] ) ] . obo:GO_0007369 obo:IAO_0000115 "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." ; oboInOwl:hasDbXref "Wikipedia:Gastrulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007369" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "gastrulation" ; rdfs:subClassOf obo:GO_0048598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0001705 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0001706 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0001707 ] . obo:GO_0007389 obo:IAO_0000115 "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pattern biosynthesis", "pattern formation" ; oboInOwl:id "GO:0007389" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "pattern specification process" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0007398 obo:IAO_0000115 "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007398" ; a owl:Class ; rdfs:label "ectoderm development" ; rdfs:subClassOf obo:GO_0009888, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000924 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000924 ] ) ] . obo:GO_0007399 obo:IAO_0000115 "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pan-neural process" ; oboInOwl:id "GO:0007399" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "nervous system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001016 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001016 ] ) ] . obo:GO_0007405 obo:IAO_0000115 "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron." ; oboInOwl:hasAlternativeId "GO:0043349", "GO:0043350" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007405" ; a owl:Class ; rdfs:label "neuroblast proliferation" ; rdfs:subClassOf obo:GO_0061351, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048699 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000031 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000031 ] ) ] . obo:GO_0007406 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts." ; oboInOwl:hasExactSynonym "down regulation of neuroblast proliferation", "down-regulation of neuroblast proliferation", "downregulation of neuroblast proliferation", "suppression of neuroblast proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of neuroblast proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007406" ; a owl:Class ; rdfs:label "negative regulation of neuroblast proliferation" ; rdfs:subClassOf obo:GO_0050768, obo:GO_1902692, obo:GO_2000178, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007405 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007405 ] ) ] . obo:GO_0007407 obo:IAO_0000115 "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." ; oboInOwl:hasAlternativeId "GO:0043351", "GO:0043352" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007407" ; a owl:Class ; rdfs:label "neuroblast activation" ; rdfs:subClassOf obo:GO_0001775, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048699 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000031 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000031 ] ) ] . obo:GO_0007409 obo:IAO_0000115 "De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells." ; oboInOwl:hasAlternativeId "GO:0007410" ; oboInOwl:hasExactSynonym "axon morphogenesis", "neuron long process generation" ; oboInOwl:hasNarrowSynonym "axon growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007409" ; a owl:Class ; rdfs:comment "Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon)." ; rdfs:label "axonogenesis" ; rdfs:subClassOf obo:GO_0048812, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048667 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061564 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0030424 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0030424 ] ) ] . obo:GO_0007411 obo:IAO_0000115 "The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues." ; oboInOwl:hasAlternativeId "GO:0008040" ; oboInOwl:hasDbXref "Wikipedia:Axon_guidance" ; oboInOwl:hasExactSynonym "axon pathfinding" ; oboInOwl:hasNarrowSynonym "axon growth cone guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "axon chemotaxis" ; oboInOwl:id "GO:0007411" ; a owl:Class ; rdfs:label "axon guidance" ; rdfs:subClassOf obo:GO_0097485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007409 ] . obo:GO_0007413 obo:IAO_0000115 "The collection of axons into a bundle of rods, known as a fascicle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "fasciculation of neuron" ; oboInOwl:id "GO:0007413" ; a owl:Class ; rdfs:label "axonal fasciculation" ; rdfs:subClassOf obo:GO_0008038, obo:GO_0106030, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061564 ] . obo:GO_0007416 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." ; oboInOwl:hasDbXref "Wikipedia:Synaptogenesis" ; oboInOwl:hasExactSynonym "synapse biogenesis", "synaptogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007416" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synapse assembly" ; rdfs:subClassOf obo:GO_0034329, obo:GO_0050808, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0007417 obo:IAO_0000115 "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." ; oboInOwl:hasDbXref "Wikipedia:Neural_development" ; oboInOwl:hasExactSynonym "CNS development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007417" ; a owl:Class ; rdfs:label "central nervous system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001017 ] ) ] . obo:GO_0007420 obo:IAO_0000115 "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007420" ; a owl:Class ; rdfs:label "brain development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007417 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060322 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000955 ] ) ] . obo:GO_0007422 obo:IAO_0000115 "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007422" ; a owl:Class ; rdfs:label "peripheral nervous system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000010 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000010 ] ) ] . obo:GO_0007423 obo:IAO_0000115 "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure." ; oboInOwl:hasExactSynonym "sense organ development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007423" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "sensory organ development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000020 ] ) ] . obo:GO_0007439 obo:IAO_0000115 "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ectodermal gut development" ; oboInOwl:id "GO:0007439" ; a owl:Class ; rdfs:label "ectodermal digestive tract development" ; rdfs:subClassOf obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048565 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004906 ] ) ] . obo:GO_0007440 obo:IAO_0000115 "The process in which the anatomical structures of the foregut are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007440" ; a owl:Class ; rdfs:label "foregut morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048546 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001041 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001041 ] ) ] . obo:GO_0007442 obo:IAO_0000115 "The process in which the anatomical structures of the hindgut are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007442" ; a owl:Class ; rdfs:label "hindgut morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048546 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061525 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001046 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001046 ] ) ] . obo:GO_0007492 obo:IAO_0000115 "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007492" ; a owl:Class ; rdfs:label "endoderm development" ; rdfs:subClassOf obo:GO_0009888, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000925 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000925 ] ) ] . obo:GO_0007494 obo:IAO_0000115 "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007494" ; a owl:Class ; rdfs:label "midgut development" ; rdfs:subClassOf obo:GO_0048565, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001045 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001045 ] ) ] . obo:GO_0007498 obo:IAO_0000115 "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007498" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "mesoderm development" ; rdfs:subClassOf obo:GO_0009888, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000926 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000926 ] ) ] . obo:GO_0007506 obo:IAO_0000115 "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007506" ; a owl:Class ; rdfs:label "gonadal mesoderm development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0007498, obo:GO_0060485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008406 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003855 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003855 ] ) ] . obo:GO_0007507 obo:IAO_0000115 "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood." ; oboInOwl:hasAlternativeId "GO:0007511" ; oboInOwl:hasDbXref "Wikipedia:Heart_development" ; oboInOwl:hasNarrowSynonym "dorsal vessel development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiac development" ; oboInOwl:id "GO:0007507" ; a owl:Class ; rdfs:label "heart development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072359 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0007100 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0007100 ] ) ] . obo:GO_0007517 obo:IAO_0000115 "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007517" ; a owl:Class ; rdfs:label "muscle organ development" ; rdfs:subClassOf obo:GO_0048513, obo:GO_0061061, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001630 ] ) ] . obo:GO_0007519 obo:IAO_0000115 "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers." ; oboInOwl:hasAlternativeId "GO:0048637" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "myogenesis" ; oboInOwl:id "GO:0007519" ; a owl:Class ; rdfs:label "skeletal muscle tissue development" ; rdfs:subClassOf obo:GO_0014706, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060538 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001134 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001134 ] ) ] . obo:GO_0007528 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction." ; oboInOwl:hasExactSynonym "neuromuscular junction organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "NMJ stability", "neuromuscular junction stability" ; oboInOwl:id "GO:0007528" ; a owl:Class ; rdfs:label "neuromuscular junction development" ; rdfs:subClassOf obo:GO_0050808, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031594 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031594 ] ) ] . obo:GO_0007530 obo:IAO_0000115 "Any process that establishes and transmits the specification of sexual status of an individual organism." ; oboInOwl:hasDbXref "Wikipedia:Sex-determination_system" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007530" ; a owl:Class ; rdfs:label "sex determination" ; rdfs:subClassOf obo:GO_0003006 . obo:GO_0007548 obo:IAO_0000115 "The establishment of the sex of an organism by physical differentiation." ; oboInOwl:hasDbXref "Wikipedia:Sexual_differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007548" ; a owl:Class ; rdfs:label "sex differentiation" ; rdfs:subClassOf obo:GO_0003006 . obo:GO_0007549 obo:IAO_0000115 "Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes." ; oboInOwl:hasDbXref "Wikipedia:Dosage_compensation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007549" ; a owl:Class ; rdfs:label "dosage compensation" ; rdfs:subClassOf obo:GO_0040029 . obo:GO_0007565 obo:IAO_0000115 "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth." ; oboInOwl:hasDbXref "Wikipedia:Gestation" ; oboInOwl:hasExactSynonym "gestation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "carrying of young" ; oboInOwl:id "GO:0007565" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "female pregnancy" ; rdfs:subClassOf obo:GO_0044703, obo:GO_0044706, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_40674 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_40674 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0007566 obo:IAO_0000115 "Attachment of the blastocyst to the uterine lining." ; oboInOwl:hasExactSynonym "blastocyst implantation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007566" ; a owl:Class ; rdfs:label "embryo implantation" ; rdfs:subClassOf obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007565 ] . obo:GO_0007568 obo:IAO_0000115 "OBSOLETE. A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24930"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0016280" ; oboInOwl:hasExactSynonym "ageing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007568" ; a owl:Class ; rdfs:comment "The reason for obsoletion is that this represents a phenotype." ; rdfs:label "obsolete aging" ; owl:deprecated true . obo:GO_0007585 obo:IAO_0000115 "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms." ; oboInOwl:hasBroadSynonym "breathing", "respiration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007585" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "respiratory gaseous exchange by respiratory system" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0007586 obo:IAO_0000115 "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasDbXref "Wikipedia:Digestion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007586" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "digestion" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0007588 obo:IAO_0000115 "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22368"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Excretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007588" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:label "excretion" ; rdfs:subClassOf obo:GO_0003008 . obo:GO_0007589 obo:IAO_0000115 "The controlled release of a fluid by a cell or tissue in an animal." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007589" ; a owl:Class ; rdfs:label "body fluid secretion" ; rdfs:subClassOf obo:GO_0046903, obo:GO_0050878 . obo:GO_0007600 obo:IAO_0000115 "The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." ; oboInOwl:hasDbXref "Wikipedia:Perception" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007600" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "sensory perception" ; rdfs:subClassOf obo:GO_0050877 . obo:GO_0007601 obo:IAO_0000115 "The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image." ; oboInOwl:hasDbXref "Wikipedia:Visual_perception" ; oboInOwl:hasExactSynonym "sense of sight", "sensory visual perception", "vision" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007601" ; a owl:Class ; rdfs:label "visual perception" ; rdfs:subClassOf obo:GO_0050953 . obo:GO_0007605 obo:IAO_0000115 "The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound." ; oboInOwl:hasDbXref "Wikipedia:Hearing_(sense)" ; oboInOwl:hasExactSynonym "hearing", "perception of sound" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007605" ; a owl:Class ; rdfs:label "sensory perception of sound" ; rdfs:subClassOf obo:GO_0050954 . obo:GO_0007610 obo:IAO_0000115 "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-20T14:06:08Z" ; oboInOwl:hasAlternativeId "GO:0023032", "GO:0044708", "GO:0044709" ; oboInOwl:hasDbXref "Wikipedia:Behavior" ; oboInOwl:hasExactSynonym "behavioral response to stimulus", "behaviour", "behavioural response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism behavior" ; oboInOwl:id "GO:0007610" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_agr, go:goslim_flybase_ribbon ; a owl:Class ; rdfs:comment """1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews. 2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).""" ; rdfs:label "behavior" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:UBERON_0001016 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith obo:GO_0032502 . obo:GO_0007611 obo:IAO_0000115 "The acquisition and processing of information and/or the storage and retrieval of this information over time." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007611" ; a owl:Class ; rdfs:label "learning or memory" ; rdfs:subClassOf obo:GO_0007610, obo:GO_0050890 . obo:GO_0007612 obo:IAO_0000115 "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience." ; oboInOwl:hasDbXref "Wikipedia:Learning" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007612" ; a owl:Class ; rdfs:label "learning" ; rdfs:subClassOf obo:GO_0007611 . obo:GO_0007613 obo:IAO_0000115 "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." ; oboInOwl:hasDbXref "Wikipedia:Memory" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007613" ; a owl:Class ; rdfs:label "memory" ; rdfs:subClassOf obo:GO_0007611 . obo:GO_0007617 obo:IAO_0000115 "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." ; oboInOwl:hasDbXref "Wikipedia:Mating_behaviour" ; oboInOwl:hasExactSynonym "mating behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007617" ; a owl:Class ; rdfs:label "mating behavior" ; rdfs:subClassOf obo:GO_0019098 . obo:GO_0007618 obo:IAO_0000115 "The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007618" ; a owl:Class ; rdfs:label "mating" ; rdfs:subClassOf obo:GO_0044703, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019953 ] . obo:GO_0007620 obo:IAO_0000115 "The act of sexual union between male and female, involving the transfer of sperm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007620" ; a owl:Class ; rdfs:label "copulation" ; rdfs:subClassOf obo:GO_0007617 . obo:GO_0007622 obo:IAO_0000115 "The specific behavior of an organism that recur with measured regularity." ; oboInOwl:hasExactSynonym "rhythmic behavioral response to stimulus", "rhythmic behaviour", "rhythmic behavioural response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007622" ; a owl:Class ; rdfs:label "rhythmic behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0007623 obo:IAO_0000115 "Any biological process in an organism that recurs with a regularity of approximately 24 hours." ; oboInOwl:hasAlternativeId "GO:0050895" ; oboInOwl:hasDbXref "Wikipedia:Circadian_rhythm" ; oboInOwl:hasExactSynonym "circadian process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "circadian response", "response to circadian rhythm" ; oboInOwl:id "GO:0007623" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_plant ; a owl:Class ; rdfs:label "circadian rhythm" ; rdfs:subClassOf obo:GO_0048511 . obo:GO_0007624 obo:IAO_0000115 "The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007624" ; a owl:Class ; rdfs:label "ultradian rhythm" ; rdfs:subClassOf obo:GO_0048511 . obo:GO_0007626 obo:IAO_0000115 "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." ; oboInOwl:hasExactSynonym "behavior via locomotion", "locomotion in response to stimulus", "locomotory behavioral response to stimulus", "locomotory behaviour", "locomotory behavioural response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007626" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "locomotory behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0007631 obo:IAO_0000115 "Behavior associated with the intake of food." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/18547"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2011-10-27T03:53:33Z" ; oboInOwl:hasAlternativeId "GO:0044366", "GO:0044367", "GO:0044368", "GO:0044369", "GO:0044370", "GO:0044371", "GO:0044372" ; oboInOwl:hasDbXref "Wikipedia:List_of_feeding_behaviours" ; oboInOwl:hasExactSynonym "behavioral response to food", "behavioural response to food", "feeding behaviour" ; oboInOwl:hasNarrowSynonym "eating", "feeding from phloem of other organism", "feeding from plant phloem", "feeding from tissue of other organism", "feeding from vascular tissue of another organism", "feeding from xylem of other organism", "feeding on blood of other organism", "feeding on or from other organism", "feeding on plant sap", "hematophagy", "injection of substance into other organism during feeding on blood of other organism", "taking of blood meal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007631" ; a owl:Class ; rdfs:comment "See also the biological process term 'behavior ; GO:0007610'." ; rdfs:label "feeding behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0007635 obo:IAO_0000115 "Behavior that is dependent upon the sensation of chemicals." ; oboInOwl:hasExactSynonym "behavioral response to chemical stimulus", "behavioural response to chemical stimulus", "chemosensory behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007635" ; a owl:Class ; rdfs:label "chemosensory behavior" ; rdfs:subClassOf obo:GO_0007610, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042221 ] . obo:GO_0008015 obo:IAO_0000115 "The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products." ; oboInOwl:hasAlternativeId "GO:0070261" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "hemolymph circulation" ; oboInOwl:id "GO:0008015" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "blood circulation" ; rdfs:subClassOf obo:GO_0003013 . obo:GO_0008016 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body." ; oboInOwl:hasExactSynonym "regulation of cardiac contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008016" ; a owl:Class ; rdfs:label "regulation of heart contraction" ; rdfs:subClassOf obo:GO_1903522, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060047 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060047 ] ) ] . obo:GO_0008017 obo:IAO_0000115 "Binding to a microtubule, a filament composed of tubulin monomers." ; oboInOwl:hasDbXref "Reactome:R-HSA-9614343" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "microtubule severing activity", "microtubule/chromatin interaction" ; oboInOwl:id "GO:0008017" ; a owl:Class ; rdfs:label "microtubule binding" ; rdfs:subClassOf obo:GO_0015631, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005874 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0008021 obo:IAO_0000115 "A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1071221672", "Wikipedia:Synaptic_vesicle" ; oboInOwl:hasNarrowSynonym "docked vesicle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0008021" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "This term should not be confused with GO:0097547 'synaptic vesicle protein transport vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles." ; rdfs:label "synaptic vesicle" ; rdfs:subClassOf obo:GO_0070382, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] . obo:GO_0008028 obo:IAO_0000115 "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group." ; oboInOwl:hasAlternativeId "GO:0008505" ; oboInOwl:hasDbXref "Reactome:R-HSA-429749", "Reactome:R-HSA-433698", "Reactome:R-HSA-5624211", "Reactome:R-HSA-9645220" ; oboInOwl:hasNarrowSynonym "monocarboxylate carrier", "prostaglandin/thromboxane transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0008028" ; a owl:Class ; rdfs:label "monocarboxylic acid transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0005342, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015718 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25384 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25384 ] ) ] . obo:GO_0008037 obo:IAO_0000115 "The process in which a cell in an organism interprets its surroundings." ; oboInOwl:hasExactSynonym "recognition of surroundings by cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008037" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cell recognition" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0008038 obo:IAO_0000115 "The process in which a neuronal cell in a multicellular organism interprets its surroundings." ; oboInOwl:hasExactSynonym "neuronal cell recognition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008038" ; a owl:Class ; rdfs:label "neuron recognition" ; rdfs:subClassOf obo:GO_0008037, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ] . obo:GO_0008078 obo:IAO_0000115 "The orderly movement of mesodermal cells from one site to another." ; oboInOwl:hasExactSynonym "mesoderm cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008078" ; a owl:Class ; rdfs:label "mesodermal cell migration" ; rdfs:subClassOf obo:GO_0001667, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000222 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000222 ] ) ] . obo:GO_0008088 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules in neuron projections." ; oboInOwl:hasDbXref "Wikipedia:Axoplasmic_transport" ; oboInOwl:hasNarrowSynonym "axon cargo transport", "axonal transport", "axoplasmic transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008088" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "axo-dendritic transport" ; rdfs:subClassOf obo:GO_0010970, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043005 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0008089 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons." ; oboInOwl:hasExactSynonym "anterograde axon cargo transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008089" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "anterograde axonal transport" ; rdfs:subClassOf obo:GO_0098930, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_1904115 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_1904115 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0008090 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons." ; oboInOwl:hasExactSynonym "retrograde axon cargo transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008090" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "retrograde axonal transport" ; rdfs:subClassOf obo:GO_0098930, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_1904115 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_1904115 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0008092 obo:IAO_0000115 "Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton)." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0008092" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "cytoskeletal protein binding" ; rdfs:subClassOf obo:GO_0005515 . obo:GO_0008104 obo:IAO_0000115 "Any process in which a protein is transported to, or maintained in, a specific location." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0008105", "GO:0016249", "GO:0034613" ; oboInOwl:hasExactSynonym "cellular protein localisation", "cellular protein localization", "protein localisation" ; oboInOwl:hasNarrowSynonym "channel localizer activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "asymmetric protein localisation", "asymmetric protein localization", "establishment and maintenance of asymmetric protein localization", "establishment and maintenance of protein localization" ; oboInOwl:id "GO:0008104" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "protein localization" ; rdfs:subClassOf obo:GO_0070727, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0008150 obo:IAO_0000115 "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.", "A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24968"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T15:05:24Z" ; oboInOwl:hasAlternativeId "GO:0000004", "GO:0007582", "GO:0044699" ; oboInOwl:hasDbXref "Wikipedia:Biological_process" ; oboInOwl:hasExactSynonym "biological process", "physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism process", "single-organism process" ; oboInOwl:id "GO:0008150" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ; rdfs:label "biological_process" ; rdfs:subClassOf obo:BFO_0000015 . obo:GO_0008152 obo:IAO_0000115 "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-10-17T15:46:40Z" ; oboInOwl:hasAlternativeId "GO:0044236", "GO:0044710" ; oboInOwl:hasDbXref "Wikipedia:Metabolism" ; oboInOwl:hasExactSynonym "metabolism" ; oboInOwl:hasNarrowSynonym "metabolic process resulting in cell growth", "metabolism resulting in cell growth", "multicellular organism metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism metabolic process" ; oboInOwl:id "GO:0008152" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions." ; rdfs:label "metabolic process" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848, obo:GO_0051179 . obo:GO_0008156 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication." ; oboInOwl:hasExactSynonym "down regulation of DNA replication", "down-regulation of DNA replication", "downregulation of DNA replication" ; oboInOwl:hasNarrowSynonym "inhibition of DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA replication inhibitor" ; oboInOwl:id "GO:0008156" ; a owl:Class ; rdfs:label "negative regulation of DNA replication" ; rdfs:subClassOf obo:GO_0006275, obo:GO_0051053, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006260 ] ) ] . obo:GO_0008202 obo:IAO_0000115 "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ; oboInOwl:hasDbXref "Wikipedia:Steroid_metabolism" ; oboInOwl:hasExactSynonym "steroid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008202" ; a owl:Class ; rdfs:label "steroid metabolic process" ; rdfs:subClassOf obo:GO_0006629, obo:GO_1901360, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35341 ] ) ] . obo:GO_0008206 obo:IAO_0000115 "The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." ; oboInOwl:hasExactSynonym "bile acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008206" ; a owl:Class ; rdfs:label "bile acid metabolic process" ; rdfs:subClassOf obo:GO_0008202, obo:GO_0032787, obo:GO_1901615, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_36235 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_36235 ] ) ] . obo:GO_0008213 obo:IAO_0000115 "The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom." ; oboInOwl:hasExactSynonym "protein amino acid alkylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008213" ; oboInOwl:inSubset go:goslim_yeast, go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "protein alkylation" ; rdfs:subClassOf obo:GO_0036211 . obo:GO_0008219 obo:IAO_0000115 "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "accidental cell death", "necrosis" ; oboInOwl:id "GO:0008219" ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide) show that cell death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Also, if experimental data suggest that a gene product influences cell death indirectly, rather than being involved in the death process directly, consider annotating to a 'regulation' term." ; rdfs:label "cell death" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0008272 obo:IAO_0000115 "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasAlternativeId "GO:0006870" ; oboInOwl:hasExactSynonym "sulphate transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008272" ; a owl:Class ; rdfs:label "sulfate transport" ; rdfs:subClassOf obo:GO_0015698, obo:GO_0072348, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16189 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16189 ] ) ] . obo:GO_0008283 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a cell population." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell proliferation" ; oboInOwl:id "GO:0008283" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir ; a owl:Class ; rdfs:comment "This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms." ; rdfs:label "cell population proliferation" ; rdfs:subClassOf obo:GO_0009987, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] . obo:GO_0008284 obo:IAO_0000115 "Any process that activates or increases the rate or extent of cell proliferation." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasExactSynonym "up regulation of cell proliferation", "up-regulation of cell proliferation", "upregulation of cell proliferation" ; oboInOwl:hasNarrowSynonym "activation of cell proliferation", "stimulation of cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cell proliferation" ; oboInOwl:id "GO:0008284" ; a owl:Class ; rdfs:label "positive regulation of cell population proliferation" ; rdfs:subClassOf obo:GO_0042127, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008283 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008283 ] ) ] . obo:GO_0008285 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of cell proliferation." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasExactSynonym "down regulation of cell proliferation", "down-regulation of cell proliferation", "downregulation of cell proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell proliferation" ; oboInOwl:id "GO:0008285" ; a owl:Class ; rdfs:label "negative regulation of cell population proliferation" ; rdfs:subClassOf obo:GO_0042127, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008283 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008283 ] ) ] . obo:GO_0008289 obo:IAO_0000115 "Binding to a lipid." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0008289" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "lipid binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0008291 obo:IAO_0000115 "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ; oboInOwl:hasExactSynonym "acetylcholine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008291" ; a owl:Class ; rdfs:label "acetylcholine metabolic process" ; rdfs:subClassOf obo:GO_0042133, obo:GO_1900619, obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_15355 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_15355 ] ) ] . obo:GO_0008292 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline." ; oboInOwl:hasExactSynonym "acetylcholine anabolism", "acetylcholine biosynthesis", "acetylcholine formation", "acetylcholine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008292" ; a owl:Class ; rdfs:label "acetylcholine biosynthetic process" ; rdfs:subClassOf obo:GO_0008291, obo:GO_0042136, obo:GO_1900620, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_15355 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_15355 ] ) ] . obo:GO_0008306 obo:IAO_0000115 "Learning by associating a stimulus (the cause) with a particular outcome (the effect)." ; oboInOwl:hasDbXref "Wikipedia:Learning#Associative_learning" ; oboInOwl:hasExactSynonym "Pavlovian conditioning", "classical conditioning", "conditional learning", "conditional response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008306" ; a owl:Class ; rdfs:label "associative learning" ; rdfs:subClassOf obo:GO_0007612 . obo:GO_0008320 obo:IAO_0000115 "Enables the transfer of a protein from one side of a membrane to the other." ; oboInOwl:hasAlternativeId "GO:0015266", "GO:0015463" ; oboInOwl:hasDbXref "Reactome:R-HSA-1268022", "Reactome:R-HSA-1299475", "Reactome:R-HSA-184269", "Reactome:R-HSA-3149434", "Reactome:R-HSA-5205661", "Reactome:R-HSA-5210943", "Reactome:R-HSA-5210947", "Reactome:R-HSA-5228406", "Reactome:R-HSA-5229111", "Reactome:R-HSA-5244404", "Reactome:R-HSA-5244428", "Reactome:R-HSA-5244506", "Reactome:R-HSA-5246514", "Reactome:R-HSA-5250616", "Reactome:R-HSA-5250884", "Reactome:R-HSA-5250972", "Reactome:R-HSA-5336420", "Reactome:R-HSA-9636375", "Reactome:R-HSA-9698930", "Reactome:R-HSA-9698933" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "protein channel activity" ; oboInOwl:id "GO:0008320" ; a owl:Class ; rdfs:label "protein transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022884, obo:GO_0140318, _:genid17081 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005215 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0008324 obo:IAO_0000115 "Enables the transfer of cation from one side of a membrane to the other." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24479"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "cation transmembrane transporter activity" ; oboInOwl:hasExactSynonym "transmembrane cation transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0008324" ; a owl:Class ; rdfs:label "monoatomic cation transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015075, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098655 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_23906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_23906 ] ) ] . obo:GO_0008347 obo:IAO_0000115 "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." ; oboInOwl:hasAlternativeId "GO:0043359" ; oboInOwl:hasExactSynonym "glia cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008347" ; a owl:Class ; rdfs:label "glial cell migration" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042063 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000125 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000125 ] ) ] . obo:GO_0008354 obo:IAO_0000115 "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." ; oboInOwl:hasExactSynonym "germ-cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "primordial germ cell migration" ; oboInOwl:id "GO:0008354" ; a owl:Class ; rdfs:label "germ cell migration" ; rdfs:subClassOf obo:GO_0016477, obo:GO_0022412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007276 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000586 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000586 ] ) ] . obo:GO_0008356 obo:IAO_0000115 "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." ; oboInOwl:hasDbXref "Wikipedia:Asymmetric_cell_division" ; oboInOwl:hasExactSynonym "asymmetrical cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "asymmetric cytokinesis", "asymmetrical cytokinesis" ; oboInOwl:id "GO:0008356" ; a owl:Class ; rdfs:label "asymmetric cell division" ; rdfs:subClassOf obo:GO_0051301 . obo:GO_0008358 obo:IAO_0000115 "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008358" ; a owl:Class ; rdfs:label "maternal determination of anterior/posterior axis, embryo" ; rdfs:subClassOf obo:GO_0008595 . obo:GO_0008361 obo:IAO_0000115 "Any process that modulates the size of a cell." ; oboInOwl:hasExactSynonym "cell size control" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008361" ; a owl:Class ; rdfs:label "regulation of cell size" ; rdfs:subClassOf obo:GO_0032535 . obo:GO_0008380 obo:IAO_0000115 "The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." ; oboInOwl:hasAlternativeId "GO:0006395" ; oboInOwl:hasDbXref "Wikipedia:RNA_splicing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pre-mRNA splicing factor activity" ; oboInOwl:id "GO:0008380" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "RNA splicing" ; rdfs:subClassOf obo:GO_0006396 . obo:GO_0008406 obo:IAO_0000115 "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." ; oboInOwl:hasExactSynonym "gonadogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008406" ; a owl:Class ; rdfs:label "gonad development" ; rdfs:subClassOf obo:GO_0048513, obo:GO_0048608, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045137 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000991 ] ) ] . obo:GO_0008504 obo:IAO_0000115 "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other." ; oboInOwl:hasAlternativeId "GO:0015201" ; oboInOwl:hasDbXref "Reactome:R-HSA-372542", "Reactome:R-HSA-379393", "Reactome:R-HSA-380586", "Reactome:R-HSA-380620", "Reactome:R-HSA-444160", "Reactome:R-HSA-5660706" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0008504" ; a owl:Class ; rdfs:label "monoamine transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022804, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015844 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_63534 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_63534 ] ) ] . obo:GO_0008514 obo:IAO_0000115 "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." ; oboInOwl:hasDbXref "Reactome:R-HSA-2142859", "Reactome:R-HSA-561041", "Reactome:R-HSA-9794830" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0008514" ; a owl:Class ; rdfs:label "organic anion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015711 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25696 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25696 ] ) ] . obo:GO_0008544 obo:IAO_0000115 "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." ; obo:RO_0002161 obo:NCBITaxon_33090 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "hypodermis development" ; oboInOwl:id "GO:0008544" ; a owl:Class ; rdfs:label "epidermis development" ; rdfs:subClassOf obo:GO_0009888, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_33090 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_33090 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_33090 ] . obo:GO_0008584 obo:IAO_0000115 "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." ; oboInOwl:hasExactSynonym "testicular development", "testis development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008584" ; a owl:Class ; rdfs:label "male gonad development" ; rdfs:subClassOf obo:GO_0008406, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046546 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000473 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000473 ] ) ] . obo:GO_0008585 obo:IAO_0000115 "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure." ; obo:RO_0002161 obo:NCBITaxon_3398 ; oboInOwl:hasAlternativeId "GO:0061039" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ovarian development", "ovary development" ; oboInOwl:id "GO:0008585" ; a owl:Class ; rdfs:label "female gonad development" ; rdfs:subClassOf obo:GO_0008406, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046545 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3398 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000992 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000992 ] ) ] . obo:GO_0008594 obo:IAO_0000115 "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "photoreceptor development" ; oboInOwl:id "GO:0008594" ; a owl:Class ; rdfs:label "photoreceptor cell morphogenesis" ; rdfs:subClassOf obo:GO_0048667, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042461 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_0000210 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_0000210 ] ) ] . obo:GO_0008595 obo:IAO_0000115 "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "anterior/posterior axis determination, embryo" ; oboInOwl:id "GO:0008595" ; a owl:Class ; rdfs:label "anterior/posterior axis specification, embryo" ; rdfs:subClassOf obo:GO_0000578, obo:GO_0009948, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007351 ] . obo:GO_0008610 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." ; oboInOwl:hasExactSynonym "lipid anabolism", "lipid biosynthesis", "lipid formation", "lipid synthesis", "lipogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008610" ; a owl:Class ; rdfs:label "lipid biosynthetic process" ; rdfs:subClassOf obo:GO_0006629, obo:GO_1901576, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0008630 obo:IAO_0000115 "The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA damage response, signal transduction resulting in induction of apoptosis" ; oboInOwl:id "GO:0008630" ; a owl:Class ; rdfs:label "intrinsic apoptotic signaling pathway in response to DNA damage" ; rdfs:subClassOf obo:GO_0006974, obo:GO_0097193 . obo:GO_0008643 obo:IAO_0000115 "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y." ; oboInOwl:hasAlternativeId "GO:0006861", "GO:0008644" ; oboInOwl:hasNarrowSynonym "sugar transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008643" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "carbohydrate transport" ; rdfs:subClassOf obo:GO_0071702, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16646 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16646 ] ) ] . obo:GO_0008645 obo:IAO_0000115 "The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-04-08T10:27:23Z" ; oboInOwl:hasAlternativeId "GO:0008646", "GO:0008647", "GO:0035428" ; oboInOwl:hasNarrowSynonym "high-affinity hexose transport", "low-affinity hexose transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "hexose membrane transport", "hexose transport" ; oboInOwl:id "GO:0008645" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "hexose transmembrane transport" ; rdfs:subClassOf obo:GO_0015749, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18133 ] ) ] . obo:GO_0008652 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17904"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Amino_acid_synthesis" ; oboInOwl:hasExactSynonym "amino acid anabolism", "amino acid biosynthesis", "amino acid formation", "amino acid synthesis", "cellular amino acid biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008652" ; a owl:Class ; rdfs:label "amino acid biosynthetic process" ; rdfs:subClassOf obo:GO_0006520, obo:GO_0046394, obo:GO_1901566, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_37022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_37022 ] ) ] . obo:GO_0009056 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-10-17T15:52:35Z" ; oboInOwl:hasAlternativeId "GO:0044243", "GO:0044712" ; oboInOwl:hasDbXref "Wikipedia:Catabolism" ; oboInOwl:hasExactSynonym "breakdown", "catabolism", "degradation" ; oboInOwl:hasNarrowSynonym "multicellular organismal catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism catabolic process" ; oboInOwl:id "GO:0009056" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_plant ; a owl:Class ; rdfs:label "catabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0009057 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasAlternativeId "GO:0043285", "GO:0044266" ; oboInOwl:hasExactSynonym "biopolymer catabolic process", "macromolecule breakdown", "macromolecule catabolism", "macromolecule degradation" ; oboInOwl:hasNarrowSynonym "multicellular organismal macromolecule catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular macromolecule catabolic process", "cellular macromolecule catabolism", "cellular macromolecule degradation" ; oboInOwl:id "GO:0009057" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "macromolecule catabolic process" ; rdfs:subClassOf obo:GO_0043170, obo:GO_1901575, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33694 ] ) ] . obo:GO_0009058 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-10-17T15:52:18Z" ; oboInOwl:hasAlternativeId "GO:0044274", "GO:0044711" ; oboInOwl:hasBroadSynonym "formation" ; oboInOwl:hasDbXref "Wikipedia:Anabolism" ; oboInOwl:hasExactSynonym "anabolism", "biosynthesis", "synthesis" ; oboInOwl:hasNarrowSynonym "multicellular organismal biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism biosynthetic process" ; oboInOwl:id "GO:0009058" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:label "biosynthetic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0009059 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; obo:IAO_0000233 "http://amigo.geneontology.org/amigo/term/GO:0070589"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0043284" ; oboInOwl:hasExactSynonym "biopolymer biosynthetic process", "macromolecule anabolism", "macromolecule biosynthesis", "macromolecule formation", "macromolecule synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009059" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "macromolecule biosynthetic process" ; rdfs:subClassOf obo:GO_0043170, obo:GO_1901576, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33694 ] ) ] . obo:GO_0009063 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17904"^^xsd:anyURI ; oboInOwl:hasExactSynonym "amino acid breakdown", "amino acid catabolism", "amino acid degradation", "cellular amino acid catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009063" ; a owl:Class ; rdfs:label "amino acid catabolic process" ; rdfs:subClassOf obo:GO_0006520, obo:GO_0046395, obo:GO_1901565, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_37022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_37022 ] ) ] . obo:GO_0009100 obo:IAO_0000115 "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ; oboInOwl:hasExactSynonym "glycoprotein metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009100" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "glycoprotein metabolic process" ; rdfs:subClassOf obo:GO_0019538, obo:GO_1901135, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_17089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_17089 ] ) ] . obo:GO_0009101 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ; oboInOwl:hasExactSynonym "glycoprotein anabolism", "glycoprotein biosynthesis", "glycoprotein formation", "glycoprotein synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009101" ; a owl:Class ; rdfs:label "glycoprotein biosynthetic process" ; rdfs:subClassOf obo:GO_0009059, obo:GO_0009100, obo:GO_1901137, obo:GO_1901566, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_17089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_17089 ] ) ] . obo:GO_0009112 obo:IAO_0000115 "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine." ; oboInOwl:hasExactSynonym "nucleobase metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009112" ; a owl:Class ; rdfs:label "nucleobase metabolic process" ; rdfs:subClassOf obo:GO_0055086, obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18282 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18282 ] ) ] . obo:GO_0009250 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." ; oboInOwl:hasExactSynonym "glucan anabolism", "glucan biosynthesis", "glucan formation", "glucan synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009250" ; a owl:Class ; rdfs:label "glucan biosynthetic process" ; rdfs:subClassOf obo:GO_0000271, obo:GO_0044042, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_37163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_37163 ] ) ] . obo:GO_0009251 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues." ; oboInOwl:hasExactSynonym "glucan breakdown", "glucan catabolism", "glucan degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009251" ; a owl:Class ; rdfs:label "glucan catabolic process" ; rdfs:subClassOf obo:GO_0000272, obo:GO_0044042, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_37163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_37163 ] ) ] . obo:GO_0009266 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus." ; oboInOwl:hasExactSynonym "response to thermal stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009266" ; a owl:Class ; rdfs:label "response to temperature stimulus" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0009268 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009268" ; a owl:Class ; rdfs:label "response to pH" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0009269 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "desiccation tolerance" ; oboInOwl:id "GO:0009269" ; a owl:Class ; rdfs:label "response to desiccation" ; rdfs:subClassOf obo:GO_0009414 . obo:GO_0009295 obo:IAO_0000115 "The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined." ; oboInOwl:hasDbXref "Wikipedia:Nucleoid" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0009295" ; a owl:Class ; rdfs:label "nucleoid" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0009299 obo:IAO_0000115 "The cellular synthesis of messenger RNA (mRNA) from a DNA template." ; oboInOwl:hasAlternativeId "GO:0061023" ; oboInOwl:hasBroadSynonym "mRNA biosynthesis", "mRNA biosynthetic process", "mRNA synthesis" ; oboInOwl:hasExactSynonym "cellular mRNA transcription" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009299" ; a owl:Class ; rdfs:label "mRNA transcription" ; rdfs:subClassOf obo:GO_0006351, obo:GO_0016071 . obo:GO_0009306 obo:IAO_0000115 "The controlled release of proteins from a cell." ; oboInOwl:hasAlternativeId "GO:0045166", "GO:0045731" ; oboInOwl:hasNarrowSynonym "glycoprotein secretion", "protein secretion during cell fate commitment", "protein secretion resulting in cell fate commitment" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009306" ; a owl:Class ; rdfs:label "protein secretion" ; rdfs:subClassOf obo:GO_0015031, obo:GO_0032940, obo:GO_0035592 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0009308 obo:IAO_0000115 "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2009-07-15T11:55:44Z" ; oboInOwl:hasAlternativeId "GO:0044106" ; oboInOwl:hasExactSynonym "amine metabolism", "cellular amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009308" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "amine metabolic process" ; rdfs:subClassOf obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_32952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_32952 ] ) ] . obo:GO_0009309 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ; oboInOwl:hasExactSynonym "amine anabolism", "amine biosynthesis", "amine formation", "amine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009309" ; a owl:Class ; rdfs:label "amine biosynthetic process" ; rdfs:subClassOf obo:GO_0009308, obo:GO_0044271, obo:GO_1901566, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_32952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_32952 ] ) ] . obo:GO_0009310 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ; oboInOwl:hasExactSynonym "amine breakdown", "amine catabolism", "amine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009310" ; a owl:Class ; rdfs:label "amine catabolic process" ; rdfs:subClassOf obo:GO_0009308, obo:GO_1901565, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32952 ] ) ] . obo:GO_0009314 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." ; oboInOwl:hasExactSynonym "response to electromagnetic radiation stimulus", "response to radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009314" ; a owl:Class ; rdfs:comment "Note that 'radiation' refers to electromagnetic radiation of any wavelength." ; rdfs:label "response to radiation" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0009408 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." ; oboInOwl:hasAlternativeId "GO:0006951" ; oboInOwl:hasNarrowSynonym "response to heat shock" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009408" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "response to heat" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0009266 . obo:GO_0009411 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." ; oboInOwl:hasExactSynonym "response to UV light stimulus", "response to UV radiation stimulus", "response to ultraviolet light stimulus", "response to ultraviolet radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009411" ; a owl:Class ; rdfs:label "response to UV" ; rdfs:subClassOf obo:GO_0009416 . obo:GO_0009414 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water." ; oboInOwl:hasExactSynonym "response to dehydration", "response to drought", "response to thirst" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "drought tolerance" ; oboInOwl:id "GO:0009414" ; a owl:Class ; rdfs:label "response to water deprivation" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0009415 . obo:GO_0009415 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water." ; oboInOwl:hasExactSynonym "response to water stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009415" ; a owl:Class ; rdfs:label "response to water" ; rdfs:subClassOf obo:GO_0001101, obo:GO_0009628, obo:GO_0010033, obo:GO_0010035, obo:GO_1901700, obo:GO_1902074 . obo:GO_0009416 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009416" ; oboInOwl:inSubset go:goslim_plant ; a owl:Class ; rdfs:label "response to light stimulus" ; rdfs:subClassOf obo:GO_0009314, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_30212 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_30212 ] ) ] . obo:GO_0009448 obo:IAO_0000115 "The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." ; oboInOwl:hasExactSynonym "4-aminobutanoate metabolic process", "4-aminobutanoate metabolism", "4-aminobutyrate metabolic process", "4-aminobutyrate metabolism", "GABA metabolic process", "GABA metabolism", "gamma-aminobutyric acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009448" ; a owl:Class ; rdfs:comment "See also the biological process term 'neurotransmitter metabolic process ; GO:0042133'." ; rdfs:label "gamma-aminobutyric acid metabolic process" ; rdfs:subClassOf obo:GO_0006520, obo:GO_0032787, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_59888 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_59888 ] ) ] . obo:GO_0009449 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." ; oboInOwl:hasExactSynonym "4-aminobutanoate biosynthesis", "4-aminobutanoate biosynthetic process", "4-aminobutyrate biosynthesis", "4-aminobutyrate biosynthetic process", "GABA biosynthesis", "GABA biosynthetic process", "gamma-aminobutyric acid anabolism", "gamma-aminobutyric acid biosynthesis", "gamma-aminobutyric acid formation", "gamma-aminobutyric acid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009449" ; a owl:Class ; rdfs:comment "See also the biological process term 'neurotransmitter biosynthetic process ; GO:0042136'." ; rdfs:label "gamma-aminobutyric acid biosynthetic process" ; rdfs:subClassOf obo:GO_0009448, obo:GO_1901576, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_59888 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_59888 ] ) ] . obo:GO_0009450 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms." ; oboInOwl:hasDbXref "MetaCyc:4AMINOBUTMETAB-PWY" ; oboInOwl:hasExactSynonym "4-aminobutanoate catabolic process", "4-aminobutanoate catabolism", "4-aminobutyrate catabolic process", "4-aminobutyrate catabolism", "GABA catabolic process", "GABA catabolism", "gamma-aminobutyric acid breakdown", "gamma-aminobutyric acid catabolism", "gamma-aminobutyric acid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009450" ; a owl:Class ; rdfs:comment "See also the biological process term 'neurotransmitter catabolic process ; GO:0042135'." ; rdfs:label "gamma-aminobutyric acid catabolic process" ; rdfs:subClassOf obo:GO_0009448, obo:GO_1901575, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59888 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59888 ] ) ] . obo:GO_0009453 obo:IAO_0000115 "The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates." ; oboInOwl:hasExactSynonym "energytaxis", "taxis in response to energy source" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009453" ; a owl:Class ; rdfs:label "energy taxis" ; rdfs:subClassOf obo:GO_0042330 . obo:GO_0009566 obo:IAO_0000115 "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20176"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Fertilisation" ; oboInOwl:hasExactSynonym "syngamy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009566" ; a owl:Class ; rdfs:label "fertilization" ; rdfs:subClassOf obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019953 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:CL_0010017 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0043073 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022414 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:CL_0010017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0043073 ] ) ] . obo:GO_0009581 obo:IAO_0000115 "The series of events in which an external stimulus is received by a cell and converted into a molecular signal." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "perception of external stimulus" ; oboInOwl:id "GO:0009581" ; a owl:Class ; rdfs:label "detection of external stimulus" ; rdfs:subClassOf obo:GO_0009605, obo:GO_0051606 . obo:GO_0009582 obo:IAO_0000115 "The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "perception of abiotic stimulus" ; oboInOwl:id "GO:0009582" ; a owl:Class ; rdfs:label "detection of abiotic stimulus" ; rdfs:subClassOf obo:GO_0009628, obo:GO_0051606 . obo:GO_0009583 obo:IAO_0000115 "The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal." ; oboInOwl:hasExactSynonym "detection of light" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "perception of light" ; oboInOwl:id "GO:0009583" ; a owl:Class ; rdfs:label "detection of light stimulus" ; rdfs:subClassOf obo:GO_0009416, obo:GO_0009581, obo:GO_0009582 . obo:GO_0009584 obo:IAO_0000115 "The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "perception of visible light" ; oboInOwl:id "GO:0009584" ; a owl:Class ; rdfs:label "detection of visible light" ; rdfs:subClassOf obo:GO_0009583 . obo:GO_0009605 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." ; oboInOwl:hasExactSynonym "response to environmental stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009605" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_drosophila, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to external stimulus" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0009607 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." ; oboInOwl:hasNarrowSynonym "response to biotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009607" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to biotic stimulus" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0009611 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism." ; oboInOwl:hasAlternativeId "GO:0002245" ; oboInOwl:hasExactSynonym "physiological response to wounding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009611" ; a owl:Class ; rdfs:label "response to wounding" ; rdfs:subClassOf obo:GO_0006950 . obo:GO_0009617 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium." ; oboInOwl:hasAlternativeId "GO:0009618", "GO:0009680" ; oboInOwl:hasExactSynonym "response to bacteria" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009617" ; a owl:Class ; rdfs:label "response to bacterium" ; rdfs:subClassOf obo:GO_0051707, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_2 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_2 ] ) ] . obo:GO_0009620 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus." ; oboInOwl:hasAlternativeId "GO:0009621" ; oboInOwl:hasExactSynonym "response to fungi" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009620" ; a owl:Class ; rdfs:label "response to fungus" ; rdfs:subClassOf obo:GO_0051707, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ) ] . obo:GO_0009628 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/16572"^^xsd:anyURI ; oboInOwl:hasNarrowSynonym "response to abiotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009628" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to abiotic stimulus" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0009629 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus." ; oboInOwl:hasExactSynonym "response to gravitational stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009629" ; a owl:Class ; rdfs:label "response to gravity" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0009636 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." ; oboInOwl:hasNarrowSynonym "detoxification response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "toxin resistance", "toxin susceptibility/resistance" ; oboInOwl:id "GO:0009636" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "response to toxic substance" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0009653 obo:IAO_0000115 "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." ; oboInOwl:hasBroadSynonym "embryogenesis and morphogenesis" ; oboInOwl:hasDbXref "Wikipedia:Morphogenesis" ; oboInOwl:hasExactSynonym "anatomical structure organization", "morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009653" ; a owl:Class ; rdfs:label "anatomical structure morphogenesis" ; rdfs:subClassOf obo:GO_0032502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048856 ] ; owl:disjointWith obo:GO_0048856, obo:GO_0071695 . obo:GO_0009712 obo:IAO_0000115 "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "catechol metabolic process", "catechol metabolism" ; oboInOwl:id "GO:0009712" ; a owl:Class ; rdfs:label "catechol-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0018958, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33566 ] ) ] . obo:GO_0009713 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "catechol anabolism", "catechol biosynthesis", "catechol biosynthetic process", "catechol formation", "catechol synthesis" ; oboInOwl:id "GO:0009713" ; a owl:Class ; rdfs:label "catechol-containing compound biosynthetic process" ; rdfs:subClassOf obo:GO_0009712, obo:GO_0046189, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33566 ] ) ] . obo:GO_0009719 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009719" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to endogenous stimulus" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0009725 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus." ; oboInOwl:hasExactSynonym "response to hormone stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "growth regulator" ; oboInOwl:id "GO:0009725" ; a owl:Class ; rdfs:label "response to hormone" ; rdfs:subClassOf obo:GO_0009719, obo:GO_0010033 . obo:GO_0009743 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." ; oboInOwl:hasExactSynonym "response to carbohydrate stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009743" ; a owl:Class ; rdfs:label "response to carbohydrate" ; rdfs:subClassOf obo:GO_0010033, obo:GO_1901700, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16646 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16646 ] ) ] . obo:GO_0009746 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." ; oboInOwl:hasExactSynonym "response to hexose stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009746" ; a owl:Class ; rdfs:label "response to hexose" ; rdfs:subClassOf obo:GO_0034284, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18133 ] ) ] . obo:GO_0009749 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." ; oboInOwl:hasExactSynonym "response to glucose stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009749" ; a owl:Class ; rdfs:label "response to glucose" ; rdfs:subClassOf obo:GO_0009746, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_17234 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_17234 ] ) ] . obo:GO_0009786 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of asymmetric cell division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009786" ; a owl:Class ; rdfs:label "regulation of asymmetric cell division" ; rdfs:subClassOf obo:GO_0051302, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008356 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008356 ] ) ] . obo:GO_0009790 obo:IAO_0000115 "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." ; oboInOwl:hasAlternativeId "GO:0009795" ; oboInOwl:hasBroadSynonym "embryogenesis and morphogenesis" ; oboInOwl:hasDbXref "Wikipedia:Embryogenesis" ; oboInOwl:hasExactSynonym "embryogenesis", "embryonal development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009790" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_chembl, go:goslim_plant ; a owl:Class ; rdfs:label "embryo development" ; rdfs:subClassOf obo:GO_0007275, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000922 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000922 ] ) ] . obo:GO_0009791 obo:IAO_0000115 "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009791" ; oboInOwl:inSubset go:goslim_plant ; a owl:Class ; rdfs:label "post-embryonic development" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0009792 obo:IAO_0000115 "The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell." ; oboInOwl:hasBroadSynonym "embryogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009792" ; a owl:Class ; rdfs:label "embryo development ending in birth or egg hatching" ; rdfs:subClassOf obo:GO_0009790, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0009798 obo:IAO_0000115 "The establishment, maintenance and elaboration of a pattern along a line or around a point." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "axis determination" ; oboInOwl:id "GO:0009798" ; a owl:Class ; rdfs:label "axis specification" ; rdfs:subClassOf obo:GO_0007389 . obo:GO_0009820 obo:IAO_0000115 "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." ; oboInOwl:hasExactSynonym "alkaloid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009820" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "alkaloid metabolic process" ; rdfs:subClassOf obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_22315 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_22315 ] ) ] . obo:GO_0009821 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases)." ; oboInOwl:hasDbXref "UM-BBD_enzymeID:e0711" ; oboInOwl:hasExactSynonym "alkaloid anabolism", "alkaloid biosynthesis", "alkaloid formation", "alkaloid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009821" ; a owl:Class ; rdfs:label "alkaloid biosynthetic process" ; rdfs:subClassOf obo:GO_0009820, obo:GO_0044550, obo:GO_1901566, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_22315 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_22315 ] ) ] . obo:GO_0009822 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases)." ; oboInOwl:hasExactSynonym "alkaloid breakdown", "alkaloid catabolism", "alkaloid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009822" ; a owl:Class ; rdfs:label "alkaloid catabolic process" ; rdfs:subClassOf obo:GO_0009820, obo:GO_0044270, obo:GO_1901565, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_22315 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_22315 ] ) ] . obo:GO_0009880 obo:IAO_0000115 "The process that results in the patterns of cell differentiation that will arise in an embryo." ; oboInOwl:hasBroadSynonym "embryonic pattern biosynthesis", "embryonic pattern formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ventral/lateral system" ; oboInOwl:id "GO:0009880" ; a owl:Class ; rdfs:label "embryonic pattern specification" ; rdfs:subClassOf obo:GO_0007389, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ] . obo:GO_0009887 obo:IAO_0000115 "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ; oboInOwl:hasBroadSynonym "histogenesis and organogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009887" ; a owl:Class ; rdfs:label "animal organ morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048513 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000062 ] ) ] . obo:GO_0009888 obo:IAO_0000115 "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." ; obo:RO_0002161 obo:NCBITaxon_147554, obo:NCBITaxon_33630, obo:NCBITaxon_33682, obo:NCBITaxon_38254, obo:NCBITaxon_4891 ; oboInOwl:hasBroadSynonym "histogenesis and organogenesis" ; oboInOwl:hasDbXref "Wikipedia:Histogenesis" ; oboInOwl:hasExactSynonym "histogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009888" ; a owl:Class ; rdfs:label "tissue development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_147554 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_33630 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_33682 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_38254 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4891 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_147554 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_33630 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_33682 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_38254 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4891 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000479 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_147554 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_33630 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_33682 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_38254 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4891 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000479 ] ) ] . obo:GO_0009889 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ; oboInOwl:hasExactSynonym "regulation of anabolism", "regulation of biosynthesis", "regulation of formation", "regulation of synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009889" ; a owl:Class ; rdfs:label "regulation of biosynthetic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009058 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009058 ] ) ] . obo:GO_0009890 obo:IAO_0000115 "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." ; oboInOwl:hasExactSynonym "down regulation of biosynthetic process", "down-regulation of biosynthetic process", "downregulation of biosynthetic process", "negative regulation of anabolism", "negative regulation of biosynthesis", "negative regulation of formation", "negative regulation of synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009890" ; a owl:Class ; rdfs:label "negative regulation of biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0009892, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009058 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009058 ] ) ] . obo:GO_0009891 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ; oboInOwl:hasExactSynonym "positive regulation of anabolism", "positive regulation of biosynthesis", "positive regulation of formation", "positive regulation of synthesis", "up regulation of biosynthetic process", "up-regulation of biosynthetic process", "upregulation of biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of biosynthetic process", "stimulation of biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009891" ; a owl:Class ; rdfs:label "positive regulation of biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0009893, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009058 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009058 ] ) ] . obo:GO_0009892 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ; oboInOwl:hasAlternativeId "GO:0044252" ; oboInOwl:hasExactSynonym "down regulation of metabolic process", "down-regulation of metabolic process", "downregulation of metabolic process", "negative regulation of metabolism", "negative regulation of organismal metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of metabolic process", "inhibition of organismal metabolic process", "negative regulation of multicellular organismal metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009892" ; a owl:Class ; rdfs:label "negative regulation of metabolic process" ; rdfs:subClassOf obo:GO_0019222, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008152 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008152 ] ) ] . obo:GO_0009893 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ; oboInOwl:hasAlternativeId "GO:0044253" ; oboInOwl:hasExactSynonym "positive regulation of metabolism", "up regulation of metabolic process", "up-regulation of metabolic process", "upregulation of metabolic process" ; oboInOwl:hasNarrowSynonym "activation of metabolic process", "positive regulation of multicellular organismal metabolic process", "positive regulation of organismal metabolism", "stimulation of metabolic process", "stimulation of organismal metabolic process", "up-regulation of organismal metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009893" ; a owl:Class ; rdfs:label "positive regulation of metabolic process" ; rdfs:subClassOf obo:GO_0019222, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008152 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008152 ] ) ] . obo:GO_0009894 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." ; oboInOwl:hasExactSynonym "regulation of breakdown", "regulation of catabolism", "regulation of degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009894" ; a owl:Class ; rdfs:label "regulation of catabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009056 ] ) ] . obo:GO_0009895 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." ; oboInOwl:hasExactSynonym "down regulation of catabolic process", "down-regulation of catabolic process", "downregulation of catabolic process", "negative regulation of breakdown", "negative regulation of catabolism", "negative regulation of degradation" ; oboInOwl:hasNarrowSynonym "inhibition of catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009895" ; a owl:Class ; rdfs:label "negative regulation of catabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0009894, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009056 ] ) ] . obo:GO_0009896 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." ; oboInOwl:hasExactSynonym "positive regulation of breakdown", "positive regulation of catabolism", "positive regulation of degradation", "up regulation of catabolic process", "up-regulation of catabolic process", "upregulation of catabolic process" ; oboInOwl:hasNarrowSynonym "activation of catabolic process", "stimulation of catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009896" ; a owl:Class ; rdfs:label "positive regulation of catabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0009894, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009056 ] ) ] . obo:GO_0009913 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis." ; oboInOwl:hasAlternativeId "GO:0043355" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "hypodermal cell differentiation" ; oboInOwl:id "GO:0009913" ; a owl:Class ; rdfs:label "epidermal cell differentiation" ; rdfs:subClassOf obo:GO_0030855, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008544 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000362 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000362 ] ) ] . obo:GO_0009914 obo:IAO_0000115 "The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009914" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "hormone transport" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0010817 . obo:GO_0009948 obo:IAO_0000115 "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "anterior/posterior axis determination" ; oboInOwl:id "GO:0009948" ; a owl:Class ; rdfs:label "anterior/posterior axis specification" ; rdfs:subClassOf obo:GO_0009798, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009952 ] . obo:GO_0009952 obo:IAO_0000115 "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "anterior/posterior pattern formation" ; oboInOwl:id "GO:0009952" ; a owl:Class ; rdfs:label "anterior/posterior pattern specification" ; rdfs:subClassOf obo:GO_0003002 . obo:GO_0009966 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of signal transduction." ; oboInOwl:hasAlternativeId "GO:0035466" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of signaling pathway", "regulation of signalling pathway" ; oboInOwl:id "GO:0009966" ; a owl:Class ; rdfs:label "regulation of signal transduction" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0023051, obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007165 ] ) ] . obo:GO_0009967 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of signal transduction." ; oboInOwl:hasAlternativeId "GO:0035468" ; oboInOwl:hasExactSynonym "up regulation of signal transduction", "up-regulation of signal transduction", "upregulation of signal transduction" ; oboInOwl:hasNarrowSynonym "activation of signal transduction", "stimulation of signal transduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of signaling pathway", "positive regulation of signalling pathway" ; oboInOwl:id "GO:0009967" ; a owl:Class ; rdfs:label "positive regulation of signal transduction" ; rdfs:subClassOf obo:GO_0009966, obo:GO_0010647, obo:GO_0023056, obo:GO_0048584, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007165 ] ) ] . obo:GO_0009968 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." ; oboInOwl:hasAlternativeId "GO:0035467" ; oboInOwl:hasExactSynonym "down regulation of signal transduction", "down-regulation of signal transduction", "downregulation of signal transduction" ; oboInOwl:hasNarrowSynonym "inhibition of signal transduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of signaling pathway", "negative regulation of signalling pathway" ; oboInOwl:id "GO:0009968" ; a owl:Class ; rdfs:label "negative regulation of signal transduction" ; rdfs:subClassOf obo:GO_0009966, obo:GO_0010648, obo:GO_0023057, obo:GO_0048585, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007165 ] ) ] . obo:GO_0009987 obo:IAO_0000115 "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-12-11T16:56:55Z" ; oboInOwl:hasAlternativeId "GO:0008151", "GO:0044763", "GO:0050875" ; oboInOwl:hasExactSynonym "cell physiology", "cellular physiological process" ; oboInOwl:hasNarrowSynonym "cell growth and/or maintenance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism cellular process" ; oboInOwl:id "GO:0009987" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_plant ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term." ; rdfs:label "cellular process" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0009991 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009991" ; a owl:Class ; rdfs:label "response to extracellular stimulus" ; rdfs:subClassOf obo:GO_0009605 . obo:GO_0009994 obo:IAO_0000115 "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." ; oboInOwl:hasExactSynonym "oocyte cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009994" ; a owl:Class ; rdfs:label "oocyte differentiation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048477 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000023 ] ) ] . obo:GO_0009996 obo:IAO_0000115 "Any process that restricts, stops or prevents a cell from adopting a specific cell fate." ; oboInOwl:hasExactSynonym "down regulation of cell fate specification", "down-regulation of cell fate specification", "downregulation of cell fate specification", "suppression of cell fate" ; oboInOwl:hasNarrowSynonym "inhibition of cell fate specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009996" ; a owl:Class ; rdfs:label "negative regulation of cell fate specification" ; rdfs:subClassOf obo:GO_0010454, obo:GO_0042659, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001708 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001708 ] ) ] . obo:GO_0010001 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell." ; oboInOwl:hasAlternativeId "GO:0007404", "GO:0043360" ; oboInOwl:hasExactSynonym "glia cell differentiation", "neuroglia differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010001" ; a owl:Class ; rdfs:label "glial cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042063 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000125 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000125 ] ) ] . obo:GO_0010002 obo:IAO_0000115 "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ; oboInOwl:hasExactSynonym "cardiac precursor cell differentiation", "cardioblast cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiomyocyte generation" ; oboInOwl:id "GO:0010002" ; a owl:Class ; rdfs:label "cardioblast differentiation" ; rdfs:subClassOf obo:GO_0035051, obo:GO_0048863, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002664 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002664 ] ) ] . obo:GO_0010032 obo:IAO_0000115 "Compaction of chromatin structure prior to meiosis in eukaryotic cells." ; oboInOwl:hasExactSynonym "chromosome condensation involved in meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010032" ; a owl:Class ; rdfs:label "meiotic chromosome condensation" ; rdfs:subClassOf obo:GO_0030261, obo:GO_0070192 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030261 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0010033 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." ; oboInOwl:hasAlternativeId "GO:1990367" ; oboInOwl:hasNarrowSynonym "process resulting in tolerance to organic substance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010033" ; a owl:Class ; rdfs:label "response to organic substance" ; rdfs:subClassOf obo:GO_0042221, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_50860 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042221 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_50860 ] ) ] . obo:GO_0010034 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010034" ; a owl:Class ; rdfs:label "response to acetate" ; rdfs:subClassOf obo:GO_0010033, obo:GO_1901700, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_30089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_30089 ] ) ] . obo:GO_0010035 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010035" ; a owl:Class ; rdfs:label "response to inorganic substance" ; rdfs:subClassOf obo:GO_0042221, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_24835 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_24835 ] ) ] . obo:GO_0010037 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010037" ; a owl:Class ; rdfs:label "response to carbon dioxide" ; rdfs:subClassOf obo:GO_0010033, obo:GO_1901700 . obo:GO_0010038 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." ; oboInOwl:hasExactSynonym "response to metal" ; oboInOwl:hasNarrowSynonym "response to heavy metal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heavy metal sensitivity/resistance" ; oboInOwl:id "GO:0010038" ; a owl:Class ; rdfs:label "response to metal ion" ; rdfs:subClassOf obo:GO_0010035, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_25213 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_25213 ] ) ] . obo:GO_0010042 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus." ; oboInOwl:hasExactSynonym "response to manganese" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010042" ; a owl:Class ; rdfs:label "response to manganese ion" ; rdfs:subClassOf obo:GO_0010038 . obo:GO_0010044 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus." ; oboInOwl:hasExactSynonym "response to aluminium ion", "response to aluminum" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010044" ; a owl:Class ; rdfs:label "response to aluminum ion" ; rdfs:subClassOf obo:GO_0010038 . obo:GO_0010070 obo:IAO_0000115 "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "zygote asymmetric cytokinesis" ; oboInOwl:id "GO:0010070" ; a owl:Class ; rdfs:label "zygote asymmetric cell division" ; rdfs:subClassOf obo:GO_0008356, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008356 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000365 ] ) ] . obo:GO_0010160 obo:IAO_0000115 "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues." ; oboInOwl:hasAlternativeId "GO:0048862" ; oboInOwl:hasExactSynonym "organ boundary specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010160" ; a owl:Class ; rdfs:label "formation of animal organ boundary" ; rdfs:subClassOf obo:GO_0003002, obo:GO_0048859, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048645 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0000062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048859 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0000062 ] ) ] . obo:GO_0010165 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)." ; oboInOwl:hasExactSynonym "response to X-ray radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010165" ; a owl:Class ; rdfs:label "response to X-ray" ; rdfs:subClassOf obo:GO_0010212 . obo:GO_0010171 obo:IAO_0000115 "The process in which the anatomical structures of the soma are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010171" ; a owl:Class ; rdfs:label "body morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000468 ] ) ] . obo:GO_0010212 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays." ; oboInOwl:hasExactSynonym "response to ionising radiation", "response to ionizing radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010212" ; a owl:Class ; rdfs:label "response to ionizing radiation" ; rdfs:subClassOf obo:GO_0009314 . obo:GO_0010243 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." ; oboInOwl:hasExactSynonym "response to organic nitrogen" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010243" ; a owl:Class ; rdfs:label "response to organonitrogen compound" ; rdfs:subClassOf obo:GO_0010033, obo:GO_1901698, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35352 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35352 ] ) ] . obo:GO_0010256 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." ; oboInOwl:hasExactSynonym "endomembrane organization", "endomembrane system organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010256" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "endomembrane system organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0012505 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0012505 ] ) ] . obo:GO_0010260 obo:IAO_0000115 "OBSOLETE. The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22732"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0010261" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010260" ; a owl:Class ; rdfs:comment "This term was obsoleted because there is no evidence that this process exists." ; rdfs:label "obsolete animal organ senescence" ; owl:deprecated true . obo:GO_0010269 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010269" ; a owl:Class ; rdfs:label "response to selenium ion" ; rdfs:subClassOf obo:GO_0010035 . obo:GO_0010288 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010288" ; a owl:Class ; rdfs:label "response to lead ion" ; rdfs:subClassOf obo:GO_0010038 . obo:GO_0010324 obo:IAO_0000115 "The infolding of a membrane." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-02T13:58:34Z" ; oboInOwl:hasAlternativeId "GO:1902534" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism membrane invagination" ; oboInOwl:id "GO:0010324" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "membrane invagination" ; rdfs:subClassOf obo:GO_0061024 . obo:GO_0010332 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to gamma ray", "response to gamma-ray photon" ; oboInOwl:id "GO:0010332" ; a owl:Class ; rdfs:label "response to gamma radiation" ; rdfs:subClassOf obo:GO_0010212 . obo:GO_0010389 obo:IAO_0000115 "Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." ; oboInOwl:hasExactSynonym "regulation of mitotic entry" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010389" ; a owl:Class ; rdfs:label "regulation of G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_1901990, obo:GO_1902749, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000086 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000086 ] ) ] . obo:GO_0010453 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010453" ; a owl:Class ; rdfs:label "regulation of cell fate commitment" ; rdfs:subClassOf obo:GO_0050793, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045165 ] ) ] . obo:GO_0010454 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010454" ; a owl:Class ; rdfs:label "negative regulation of cell fate commitment" ; rdfs:subClassOf obo:GO_0010453, obo:GO_0045596, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045165 ] ) ] . obo:GO_0010455 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010455" ; a owl:Class ; rdfs:label "positive regulation of cell fate commitment" ; rdfs:subClassOf obo:GO_0010453, obo:GO_0045597, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045165 ] ) ] . obo:GO_0010463 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010463" ; a owl:Class ; rdfs:label "mesenchymal cell proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0008019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0008019 ] ) ] . obo:GO_0010464 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010464" ; a owl:Class ; rdfs:label "regulation of mesenchymal cell proliferation" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010463 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010463 ] ) ] . obo:GO_0010467 obo:IAO_0000115 "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, translation and maturation for protein-coding genes." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Gene_expression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010467" ; oboInOwl:inSubset go:goslim_flybase_ribbon ; a owl:Class ; rdfs:label "gene expression" ; rdfs:subClassOf obo:GO_0043170 . obo:GO_0010468 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Regulation_of_gene_expression" ; oboInOwl:hasNarrowSynonym "regulation of protein expression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "gene regulation", "regulation of gene product expression" ; oboInOwl:id "GO:0010468" ; a owl:Class ; rdfs:comment "This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation." ; rdfs:label "regulation of gene expression" ; rdfs:subClassOf obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010467 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010467 ] ) ] . obo:GO_0010470 obo:IAO_0000115 "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010470" ; a owl:Class ; rdfs:label "regulation of gastrulation" ; rdfs:subClassOf obo:GO_0022603, obo:GO_0045995, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007369 ] ) ] . obo:GO_0010481 obo:IAO_0000115 "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "hypodermal cell division" ; oboInOwl:id "GO:0010481" ; a owl:Class ; rdfs:label "epidermal cell division" ; rdfs:subClassOf obo:GO_0051301, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000362 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051301 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000362 ] ) ] . obo:GO_0010482 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of hypodermal cell division" ; oboInOwl:id "GO:0010482" ; a owl:Class ; rdfs:label "regulation of epidermal cell division" ; rdfs:subClassOf obo:GO_0051302, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010481 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010481 ] ) ] . obo:GO_0010496 obo:IAO_0000115 "The movement of substances between cells." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-19T13:24:56Z" ; oboInOwl:hasAlternativeId "GO:1902585" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism intercellular transport", "single-organism intercellular transport" ; oboInOwl:id "GO:0010496" ; a owl:Class ; rdfs:label "intercellular transport" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:CL_0000000 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:CL_0000000 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0005615 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:CL_0000000 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:CL_0000000 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0005615 ] ) ] . obo:GO_0010506 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010506" ; a owl:Class ; rdfs:label "regulation of autophagy" ; rdfs:subClassOf obo:GO_0031329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006914 ] ) ] . obo:GO_0010507 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010507" ; a owl:Class ; rdfs:label "negative regulation of autophagy" ; rdfs:subClassOf obo:GO_0010506, obo:GO_0031330, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006914 ] ) ] . obo:GO_0010508 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010508" ; a owl:Class ; rdfs:label "positive regulation of autophagy" ; rdfs:subClassOf obo:GO_0010506, obo:GO_0031331, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006914 ] ) ] . obo:GO_0010549 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of membrane disassembly." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010549" ; a owl:Class ; rdfs:label "regulation of membrane disassembly" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030397 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030397 ] ) ] . obo:GO_0010556 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010556" ; a owl:Class ; rdfs:label "regulation of macromolecule biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009059 ] ) ] . obo:GO_0010557 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010557" ; a owl:Class ; rdfs:label "positive regulation of macromolecule biosynthetic process" ; rdfs:subClassOf obo:GO_0009891, obo:GO_0010556, obo:GO_0010604, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009059 ] ) ] . obo:GO_0010558 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010558" ; a owl:Class ; rdfs:label "negative regulation of macromolecule biosynthetic process" ; rdfs:subClassOf obo:GO_0009890, obo:GO_0010556, obo:GO_0010605, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009059 ] ) ] . obo:GO_0010559 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010559" ; a owl:Class ; rdfs:label "regulation of glycoprotein biosynthetic process" ; rdfs:subClassOf obo:GO_0010556, obo:GO_1903018, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009101 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009101 ] ) ] . obo:GO_0010560 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010560" ; a owl:Class ; rdfs:label "positive regulation of glycoprotein biosynthetic process" ; rdfs:subClassOf obo:GO_0010557, obo:GO_0010559, obo:GO_1903020, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009101 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009101 ] ) ] . obo:GO_0010561 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010561" ; a owl:Class ; rdfs:label "negative regulation of glycoprotein biosynthetic process" ; rdfs:subClassOf obo:GO_0010558, obo:GO_0010559, obo:GO_1903019, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009101 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009101 ] ) ] . obo:GO_0010562 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010562" ; a owl:Class ; rdfs:label "positive regulation of phosphorus metabolic process" ; rdfs:subClassOf obo:GO_0031325, obo:GO_0051174, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006793 ] ) ] . obo:GO_0010563 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010563" ; a owl:Class ; rdfs:label "negative regulation of phosphorus metabolic process" ; rdfs:subClassOf obo:GO_0031324, obo:GO_0051174, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006793 ] ) ] . obo:GO_0010564 obo:IAO_0000115 "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010564" ; a owl:Class ; rdfs:label "regulation of cell cycle process" ; rdfs:subClassOf obo:GO_0051726, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022402 ] ) ] . obo:GO_0010565 obo:IAO_0000115 "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010565" ; a owl:Class ; rdfs:label "regulation of cellular ketone metabolic process" ; rdfs:subClassOf obo:GO_0031323, obo:GO_0062012, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042180 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042180 ] ) ] . obo:GO_0010566 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010566" ; a owl:Class ; rdfs:label "regulation of ketone biosynthetic process" ; rdfs:subClassOf obo:GO_0010565, obo:GO_0031326, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042181 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042181 ] ) ] . obo:GO_0010567 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010567" ; a owl:Class ; rdfs:label "regulation of ketone catabolic process" ; rdfs:subClassOf obo:GO_0010565, obo:GO_0031329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042182 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042182 ] ) ] . obo:GO_0010571 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." ; oboInOwl:hasExactSynonym "positive regulation of DNA replication involved in S phase", "positive regulation of DNA replication involved in S-phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of DNA replication during S phase" ; oboInOwl:id "GO:0010571" ; a owl:Class ; rdfs:label "positive regulation of nuclear cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0033262, obo:GO_0090068, obo:GO_2000105, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0033260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0033260 ] ) ] . obo:GO_0010594 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010594" ; a owl:Class ; rdfs:label "regulation of endothelial cell migration" ; rdfs:subClassOf obo:GO_0010632, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043542 ] ) ] . obo:GO_0010595 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010595" ; a owl:Class ; rdfs:label "positive regulation of endothelial cell migration" ; rdfs:subClassOf obo:GO_0010594, obo:GO_0010634, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043542 ] ) ] . obo:GO_0010596 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010596" ; a owl:Class ; rdfs:label "negative regulation of endothelial cell migration" ; rdfs:subClassOf obo:GO_0010594, obo:GO_0010633, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043542 ] ) ] . obo:GO_0010604 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010604" ; a owl:Class ; rdfs:label "positive regulation of macromolecule metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043170 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043170 ] ) ] . obo:GO_0010605 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010605" ; a owl:Class ; rdfs:label "negative regulation of macromolecule metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043170 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043170 ] ) ] . obo:GO_0010608 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." ; oboInOwl:hasExactSynonym "posttranscriptional regulation of gene expression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010608" ; a owl:Class ; rdfs:label "post-transcriptional regulation of gene expression" ; rdfs:subClassOf obo:GO_0010468 . obo:GO_0010611 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010611" ; a owl:Class ; rdfs:label "regulation of cardiac muscle hypertrophy" ; rdfs:subClassOf obo:GO_0014743, obo:GO_0043502, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003300 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003300 ] ) ] . obo:GO_0010612 obo:IAO_0000115 "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010612" ; a owl:Class ; rdfs:label "regulation of cardiac muscle adaptation" ; rdfs:subClassOf obo:GO_0043502, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014887 ] ) ] . obo:GO_0010613 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010613" ; a owl:Class ; rdfs:label "positive regulation of cardiac muscle hypertrophy" ; rdfs:subClassOf obo:GO_0010611, obo:GO_0014742, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003300 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003300 ] ) ] . obo:GO_0010614 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010614" ; a owl:Class ; rdfs:label "negative regulation of cardiac muscle hypertrophy" ; rdfs:subClassOf obo:GO_0010611, obo:GO_0014741, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003300 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003300 ] ) ] . obo:GO_0010615 obo:IAO_0000115 "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010615" ; a owl:Class ; rdfs:label "positive regulation of cardiac muscle adaptation" ; rdfs:subClassOf obo:GO_0010612, obo:GO_0014744, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014887 ] ) ] . obo:GO_0010616 obo:IAO_0000115 "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010616" ; a owl:Class ; rdfs:label "negative regulation of cardiac muscle adaptation" ; rdfs:subClassOf obo:GO_0010612, obo:GO_0014745, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014887 ] ) ] . obo:GO_0010623 obo:IAO_0000115 "The activation of endogenous cellular processes that result in the death of a cell as part of its development." ; oboInOwl:hasBroadSynonym "developmental programmed cell death", "programmed cell death involved in development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010623" ; a owl:Class ; rdfs:comment "This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure." ; rdfs:label "programmed cell death involved in cell development" ; rdfs:subClassOf obo:GO_0012501, obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0012501 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ] ) ] . obo:GO_0010628 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010628" ; a owl:Class ; rdfs:label "positive regulation of gene expression" ; rdfs:subClassOf obo:GO_0010468, obo:GO_0010604, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010467 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010467 ] ) ] . obo:GO_0010629 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "gene silencing" ; oboInOwl:id "GO:0010629" ; a owl:Class ; rdfs:comment "This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation." ; rdfs:label "negative regulation of gene expression" ; rdfs:subClassOf obo:GO_0010468, obo:GO_0010605, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010467 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010467 ] ) ] . obo:GO_0010631 obo:IAO_0000115 "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010631" ; a owl:Class ; rdfs:label "epithelial cell migration" ; rdfs:subClassOf obo:GO_0001667, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0090132 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000066 ] ) ] . obo:GO_0010632 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of epithelial cell migration." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010632" ; a owl:Class ; rdfs:label "regulation of epithelial cell migration" ; rdfs:subClassOf obo:GO_0030334, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010631 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010631 ] ) ] . obo:GO_0010633 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010633" ; a owl:Class ; rdfs:label "negative regulation of epithelial cell migration" ; rdfs:subClassOf obo:GO_0010632, obo:GO_0030336, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010631 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010631 ] ) ] . obo:GO_0010634 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of epithelial cell migration." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010634" ; a owl:Class ; rdfs:label "positive regulation of epithelial cell migration" ; rdfs:subClassOf obo:GO_0010632, obo:GO_0030335, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010631 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010631 ] ) ] . obo:GO_0010638 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ; oboInOwl:hasExactSynonym "positive regulation of organelle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of organelle organization and biogenesis" ; oboInOwl:id "GO:0010638" ; a owl:Class ; rdfs:label "positive regulation of organelle organization" ; rdfs:subClassOf obo:GO_0033043, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006996 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006996 ] ) ] . obo:GO_0010639 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ; oboInOwl:hasExactSynonym "negative regulation of organelle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of organelle organization and biogenesis" ; oboInOwl:id "GO:0010639" ; a owl:Class ; rdfs:label "negative regulation of organelle organization" ; rdfs:subClassOf obo:GO_0033043, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006996 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006996 ] ) ] . obo:GO_0010646 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010646" ; a owl:Class ; rdfs:label "regulation of cell communication" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007154 ] ) ] . obo:GO_0010647 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010647" ; a owl:Class ; rdfs:label "positive regulation of cell communication" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007154 ] ) ] . obo:GO_0010648 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010648" ; a owl:Class ; rdfs:label "negative regulation of cell communication" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007154 ] ) ] . obo:GO_0010656 obo:IAO_0000115 "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." ; oboInOwl:hasNarrowSynonym "negative regulation of muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010656" ; a owl:Class ; rdfs:label "negative regulation of muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010660, obo:GO_0043066, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010657 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010657 ] ) ] . obo:GO_0010657 obo:IAO_0000115 "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle." ; oboInOwl:hasNarrowSynonym "muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010657" ; a owl:Class ; rdfs:label "muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0006915, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:GO_0010658 obo:IAO_0000115 "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations." ; oboInOwl:hasNarrowSynonym "striated muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010658" ; a owl:Class ; rdfs:label "striated muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010657, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000737 ] ) ] . obo:GO_0010659 obo:IAO_0000115 "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." ; oboInOwl:hasNarrowSynonym "cardiac muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010659" ; a owl:Class ; rdfs:label "cardiac muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000746 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000746 ] ) ] . obo:GO_0010660 obo:IAO_0000115 "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." ; oboInOwl:hasNarrowSynonym "regulation of muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010660" ; a owl:Class ; rdfs:label "regulation of muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0042981, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010657 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010657 ] ) ] . obo:GO_0010661 obo:IAO_0000115 "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death." ; oboInOwl:hasNarrowSynonym "positive regulation of muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010661" ; a owl:Class ; rdfs:label "positive regulation of muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010660, obo:GO_0043065, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010657 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010657 ] ) ] . obo:GO_0010662 obo:IAO_0000115 "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." ; oboInOwl:hasNarrowSynonym "regulation of striated muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010662" ; a owl:Class ; rdfs:label "regulation of striated muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010660, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010658 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010658 ] ) ] . obo:GO_0010663 obo:IAO_0000115 "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." ; oboInOwl:hasNarrowSynonym "positive regulation of striated muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010663" ; a owl:Class ; rdfs:label "positive regulation of striated muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010661, obo:GO_0010662, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010658 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010658 ] ) ] . obo:GO_0010664 obo:IAO_0000115 "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death." ; oboInOwl:hasExactSynonym "down regulation of striated muscle cell apoptosis", "down-regulation of striated muscle cell apoptosis", "downregulation of striated muscle cell apoptosis" ; oboInOwl:hasNarrowSynonym "inhibition of striated muscle cell apoptosis", "negative regulation of striated muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010664" ; a owl:Class ; rdfs:label "negative regulation of striated muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010656, obo:GO_0010662, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010658 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010658 ] ) ] . obo:GO_0010665 obo:IAO_0000115 "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." ; oboInOwl:hasNarrowSynonym "regulation of cardiac muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010665" ; a owl:Class ; rdfs:label "regulation of cardiac muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010662, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010659 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010659 ] ) ] . obo:GO_0010666 obo:IAO_0000115 "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." ; oboInOwl:hasNarrowSynonym "positive regulation of cardiac muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010666" ; a owl:Class ; rdfs:label "positive regulation of cardiac muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010663, obo:GO_0010665, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010659 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010659 ] ) ] . obo:GO_0010667 obo:IAO_0000115 "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death." ; oboInOwl:hasExactSynonym "down regulation of cardiac muscle cell apoptosis", "down-regulation of cardiac muscle cell apoptosis", "downregulation of cardiac muscle cell apoptosis" ; oboInOwl:hasNarrowSynonym "inhibition of cardiac muscle cell apoptosis", "negative regulation of cardiac muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010667" ; a owl:Class ; rdfs:label "negative regulation of cardiac muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010664, obo:GO_0010665, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010659 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010659 ] ) ] . obo:GO_0010668 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010668" ; a owl:Class ; rdfs:label "ectodermal cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007398 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000221 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000221 ] ) ] . obo:GO_0010672 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-04-20T02:45:12Z" ; oboInOwl:hasAlternativeId "GO:1900401" ; oboInOwl:hasExactSynonym "regulation of transcription from RNA polymerase II promoter, meiotic" ; oboInOwl:hasNarrowSynonym "regulation of meiosis by regulation of transcription from RNA polymerase II promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010672" ; a owl:Class ; rdfs:label "regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle" ; rdfs:subClassOf obo:GO_0006357, obo:GO_0051037 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006357 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0010673 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle." ; oboInOwl:created_by "dgf" ; oboInOwl:creation_date "2012-05-01T08:40:11Z" ; oboInOwl:hasAlternativeId "GO:1900476" ; oboInOwl:hasExactSynonym "positive regulation of transcription from RNA polymerase II promoter, meiotic" ; oboInOwl:hasNarrowSynonym "activation of meiosis by positive regulation of transcription from RNA polymerase II promoter", "positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter", "stimulation of meiosis by positive regulation of transcription from RNA polymerase II promoter", "up regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter", "up-regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter", "upregulation of meiosis by positive regulation of transcription from RNA polymerase II promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010673" ; a owl:Class ; rdfs:label "positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle" ; rdfs:subClassOf obo:GO_0010672, obo:GO_0045944, obo:GO_0051039 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045944 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0010674 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle." ; oboInOwl:created_by "dgf" ; oboInOwl:creation_date "2012-05-01T08:39:58Z" ; oboInOwl:hasAlternativeId "GO:1900475" ; oboInOwl:hasExactSynonym "negative regulation of transcription from RNA polymerase II promoter, meiotic" ; oboInOwl:hasNarrowSynonym "activation of meiosis by negative regulation of transcription from RNA polymerase II promoter", "positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter", "stimulation of meiosis by negative regulation of transcription from RNA polymerase II promoter", "up regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter", "up-regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter", "upregulation of meiosis by negative regulation of transcription from RNA polymerase II promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010674" ; a owl:Class ; rdfs:label "negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle" ; rdfs:subClassOf obo:GO_0000122, obo:GO_0010672, obo:GO_0051038 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000122 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0010700 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010700" ; a owl:Class ; rdfs:label "negative regulation of norepinephrine secretion" ; rdfs:subClassOf obo:GO_0014061, obo:GO_0033604, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048243 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048243 ] ) ] . obo:GO_0010701 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010701" ; a owl:Class ; rdfs:label "positive regulation of norepinephrine secretion" ; rdfs:subClassOf obo:GO_0014061, obo:GO_0033605, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048243 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048243 ] ) ] . obo:GO_0010710 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." ; oboInOwl:hasExactSynonym "regulation of collagen breakdown", "regulation of collagen catabolism", "regulation of collagen degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010710" ; a owl:Class ; rdfs:label "regulation of collagen catabolic process" ; rdfs:subClassOf obo:GO_0009894, obo:GO_0010712, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030574 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030574 ] ) ] . obo:GO_0010711 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." ; oboInOwl:hasExactSynonym "down regulation of collagen catabolic process", "down-regulation of collagen catabolic process", "downregulation of collagen catabolic process", "negative regulation of collagen breakdown", "negative regulation of collagen catabolism", "negative regulation of collagen degradation" ; oboInOwl:hasNarrowSynonym "inhibition of collagen catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010711" ; a owl:Class ; rdfs:label "negative regulation of collagen catabolic process" ; rdfs:subClassOf obo:GO_0009895, obo:GO_0010710, obo:GO_0010713, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030574 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030574 ] ) ] . obo:GO_0010712 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ; oboInOwl:hasExactSynonym "regulation of collagen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010712" ; a owl:Class ; rdfs:label "regulation of collagen metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032963 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032963 ] ) ] . obo:GO_0010713 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010713" ; a owl:Class ; rdfs:label "negative regulation of collagen metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0010712, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032963 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032963 ] ) ] . obo:GO_0010714 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ; oboInOwl:hasExactSynonym "positive regulation of collagen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010714" ; a owl:Class ; rdfs:label "positive regulation of collagen metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0010712, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032963 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032963 ] ) ] . obo:GO_0010715 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." ; oboInOwl:hasExactSynonym "regulation of extracellular matrix breakdown", "regulation of extracellular matrix degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010715" ; a owl:Class ; rdfs:label "regulation of extracellular matrix disassembly" ; rdfs:subClassOf obo:GO_1903053, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022617 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022617 ] ) ] . obo:GO_0010716 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." ; oboInOwl:hasExactSynonym "down regulation of extracellular matrix disassembly", "down-regulation of extracellular matrix disassembly", "downregulation of extracellular matrix disassembly", "negative regulation of extracellular matrix breakdown", "negative regulation of extracellular matrix degradation" ; oboInOwl:hasNarrowSynonym "inhibition of extracellular matrix disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010716" ; a owl:Class ; rdfs:label "negative regulation of extracellular matrix disassembly" ; rdfs:subClassOf obo:GO_0010715, obo:GO_1903054, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022617 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022617 ] ) ] . obo:GO_0010717 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010717" ; a owl:Class ; rdfs:label "regulation of epithelial to mesenchymal transition" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001837 ] ) ] . obo:GO_0010718 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010718" ; a owl:Class ; rdfs:label "positive regulation of epithelial to mesenchymal transition" ; rdfs:subClassOf obo:GO_0010717, obo:GO_0045597, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001837 ] ) ] . obo:GO_0010719 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010719" ; a owl:Class ; rdfs:label "negative regulation of epithelial to mesenchymal transition" ; rdfs:subClassOf obo:GO_0010717, obo:GO_0045596, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001837 ] ) ] . obo:GO_0010720 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010720" ; a owl:Class ; rdfs:label "positive regulation of cell development" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048468 ] ) ] . obo:GO_0010721 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010721" ; a owl:Class ; rdfs:label "negative regulation of cell development" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048468 ] ) ] . obo:GO_0010761 obo:IAO_0000115 "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." ; oboInOwl:hasExactSynonym "fibroblast cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010761" ; a owl:Class ; rdfs:label "fibroblast migration" ; rdfs:subClassOf obo:GO_0001667, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000057 ] ) ] . obo:GO_0010762 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." ; oboInOwl:hasExactSynonym "regulation of fibroblast cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010762" ; a owl:Class ; rdfs:label "regulation of fibroblast migration" ; rdfs:subClassOf obo:GO_0030334, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010761 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010761 ] ) ] . obo:GO_0010763 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." ; oboInOwl:hasExactSynonym "positive regulation of fibroblast cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010763" ; a owl:Class ; rdfs:label "positive regulation of fibroblast migration" ; rdfs:subClassOf obo:GO_0010762, obo:GO_0030335, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010761 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010761 ] ) ] . obo:GO_0010764 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium." ; oboInOwl:hasExactSynonym "negative regulation of fibroblast cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010764" ; a owl:Class ; rdfs:label "negative regulation of fibroblast migration" ; rdfs:subClassOf obo:GO_0010762, obo:GO_0030336, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010761 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010761 ] ) ] . obo:GO_0010765 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010765" ; a owl:Class ; rdfs:label "positive regulation of sodium ion transport" ; rdfs:subClassOf obo:GO_0002028, obo:GO_0043270, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006814 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006814 ] ) ] . obo:GO_0010766 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010766" ; a owl:Class ; rdfs:label "negative regulation of sodium ion transport" ; rdfs:subClassOf obo:GO_0002028, obo:GO_0043271, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006814 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006814 ] ) ] . obo:GO_0010769 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010769" ; a owl:Class ; rdfs:label "regulation of cell morphogenesis involved in differentiation" ; rdfs:subClassOf obo:GO_0022604, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000904 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000904 ] ) ] . obo:GO_0010770 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010770" ; a owl:Class ; rdfs:label "positive regulation of cell morphogenesis involved in differentiation" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0010769, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000904 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000904 ] ) ] . obo:GO_0010771 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010771" ; a owl:Class ; rdfs:label "negative regulation of cell morphogenesis involved in differentiation" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0010769, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000904 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000904 ] ) ] . obo:GO_0010793 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010793" ; a owl:Class ; rdfs:label "regulation of mRNA export from nucleus" ; rdfs:subClassOf obo:GO_0046831, obo:GO_2000197, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006406 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006406 ] ) ] . obo:GO_0010817 obo:IAO_0000115 "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010817" ; a owl:Class ; rdfs:label "regulation of hormone levels" ; rdfs:subClassOf obo:GO_0065008 . obo:GO_0010818 obo:IAO_0000115 "The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." ; oboInOwl:hasExactSynonym "T-cell chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010818" ; a owl:Class ; rdfs:label "T cell chemotaxis" ; rdfs:subClassOf obo:GO_0048247, obo:GO_0072678 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006935 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0010819 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010819" ; a owl:Class ; rdfs:label "regulation of T cell chemotaxis" ; rdfs:subClassOf obo:GO_1901623, obo:GO_2000404, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010818 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010818 ] ) ] . obo:GO_0010820 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010820" ; a owl:Class ; rdfs:label "positive regulation of T cell chemotaxis" ; rdfs:subClassOf obo:GO_0010819, obo:GO_0140131, obo:GO_2000406, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010818 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010818 ] ) ] . obo:GO_0010821 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." ; oboInOwl:hasExactSynonym "regulation of mitochondrion organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010821" ; a owl:Class ; rdfs:label "regulation of mitochondrion organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007005 ] ) ] . obo:GO_0010822 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." ; oboInOwl:hasExactSynonym "positive regulation of mitochondrion organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010822" ; a owl:Class ; rdfs:label "positive regulation of mitochondrion organization" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0010821, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007005 ] ) ] . obo:GO_0010823 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." ; oboInOwl:hasExactSynonym "negative regulation of mitochondrion organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010823" ; a owl:Class ; rdfs:label "negative regulation of mitochondrion organization" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0010821, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007005 ] ) ] . obo:GO_0010827 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of glucose transport" ; oboInOwl:id "GO:0010827" ; a owl:Class ; rdfs:label "regulation of glucose transmembrane transport" ; rdfs:subClassOf obo:GO_0034762, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1904659 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1904659 ] ) ] . obo:GO_0010828 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of glucose transport" ; oboInOwl:id "GO:0010828" ; a owl:Class ; rdfs:label "positive regulation of glucose transmembrane transport" ; rdfs:subClassOf obo:GO_0010827, obo:GO_0034764, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1904659 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1904659 ] ) ] . obo:GO_0010829 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of glucose transport" ; oboInOwl:id "GO:0010829" ; a owl:Class ; rdfs:label "negative regulation of glucose transmembrane transport" ; rdfs:subClassOf obo:GO_0010827, obo:GO_0034763, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1904659 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1904659 ] ) ] . obo:GO_0010830 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010830" ; a owl:Class ; rdfs:label "regulation of myotube differentiation" ; rdfs:subClassOf obo:GO_0051153, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014902 ] ) ] . obo:GO_0010831 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010831" ; a owl:Class ; rdfs:label "positive regulation of myotube differentiation" ; rdfs:subClassOf obo:GO_0010830, obo:GO_0051155, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014902 ] ) ] . obo:GO_0010832 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010832" ; a owl:Class ; rdfs:label "negative regulation of myotube differentiation" ; rdfs:subClassOf obo:GO_0010830, obo:GO_0051154, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014902 ] ) ] . obo:GO_0010833 obo:IAO_0000115 "Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010833" ; a owl:Class ; rdfs:label "telomere maintenance via telomere lengthening" ; rdfs:subClassOf obo:GO_0000723 . obo:GO_0010842 obo:IAO_0000115 "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia." ; oboInOwl:hasExactSynonym "retinal lamination", "retinal layer formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010842" ; a owl:Class ; rdfs:label "retina layer formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003407 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060042 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001781 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001781 ] ) ] . obo:GO_0010876 obo:IAO_0000115 "Any process in which a lipid is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "lipid localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010876" ; a owl:Class ; rdfs:label "lipid localization" ; rdfs:subClassOf obo:GO_0033036, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0033036 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0010882 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction." ; oboInOwl:hasExactSynonym "regulation of cardiac muscle contraction by calcium ion signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010882" ; a owl:Class ; rdfs:label "regulation of cardiac muscle contraction by calcium ion signaling" ; rdfs:subClassOf obo:GO_0019722, obo:GO_0055117 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019722 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060048 ] ) ] . obo:GO_0010892 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010892" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial translation in response to stress" ; rdfs:subClassOf obo:GO_0032056, obo:GO_0070131 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032543 ] ) ] . obo:GO_0010893 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010893" ; a owl:Class ; rdfs:label "positive regulation of steroid biosynthetic process" ; rdfs:subClassOf obo:GO_0045940, obo:GO_0046889, obo:GO_0050810, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006694 ] ) ] . obo:GO_0010894 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010894" ; a owl:Class ; rdfs:label "negative regulation of steroid biosynthetic process" ; rdfs:subClassOf obo:GO_0045939, obo:GO_0050810, obo:GO_0051055, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006694 ] ) ] . obo:GO_0010906 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." ; oboInOwl:hasExactSynonym "regulation of glucose metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010906" ; a owl:Class ; rdfs:label "regulation of glucose metabolic process" ; rdfs:subClassOf obo:GO_0006109, obo:GO_0062012, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006006 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006006 ] ) ] . obo:GO_0010907 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose." ; oboInOwl:hasExactSynonym "positive regulation of glucose metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010907" ; a owl:Class ; rdfs:label "positive regulation of glucose metabolic process" ; rdfs:subClassOf obo:GO_0010906, obo:GO_0045913, obo:GO_0062013, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006006 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006006 ] ) ] . obo:GO_0010927 obo:IAO_0000115 "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010927" ; a owl:Class ; rdfs:label "cellular component assembly involved in morphogenesis" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032989 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ) ] . obo:GO_0010937 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010937" ; a owl:Class ; rdfs:label "regulation of cytoplasmic microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031114, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010938 ] ) ] . obo:GO_0010938 obo:IAO_0000115 "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010938" ; a owl:Class ; rdfs:label "cytoplasmic microtubule depolymerization" ; rdfs:subClassOf obo:GO_0007019, obo:GO_0031122, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007019 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0010941 obo:IAO_0000115 "Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010941" ; a owl:Class ; rdfs:label "regulation of cell death" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008219 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008219 ] ) ] . obo:GO_0010942 obo:IAO_0000115 "Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010942" ; a owl:Class ; rdfs:label "positive regulation of cell death" ; rdfs:subClassOf obo:GO_0010941, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008219 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008219 ] ) ] . obo:GO_0010948 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-04-27T09:53:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010948" ; a owl:Class ; rdfs:label "negative regulation of cell cycle process" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0045786, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022402 ] ) ] . obo:GO_0010959 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-06T11:40:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010959" ; a owl:Class ; rdfs:label "regulation of metal ion transport" ; rdfs:subClassOf obo:GO_0043269, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030001 ] ) ] . obo:GO_0010962 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-11T12:17:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010962" ; a owl:Class ; rdfs:label "regulation of glucan biosynthetic process" ; rdfs:subClassOf obo:GO_0032885, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009250 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009250 ] ) ] . obo:GO_0010965 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-20T11:39:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010965" ; a owl:Class ; rdfs:label "regulation of mitotic sister chromatid separation" ; rdfs:subClassOf obo:GO_1905818, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051306 ] ) ] . obo:GO_0010966 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-20T11:42:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010966" ; a owl:Class ; rdfs:label "regulation of phosphate transport" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006817 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006817 ] ) ] . obo:GO_0010968 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-20T11:51:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010968" ; a owl:Class ; rdfs:label "regulation of microtubule nucleation" ; rdfs:subClassOf obo:GO_0031113, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007020 ] ) ] . obo:GO_0010970 obo:IAO_0000115 "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-27T10:56:08Z" ; oboInOwl:hasBroadSynonym "microtubule-based transport" ; oboInOwl:hasExactSynonym "establishment of localization by movement along microtubule", "movement along microtubule" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010970" ; a owl:Class ; rdfs:label "transport along microtubule" ; rdfs:subClassOf obo:GO_0007018, obo:GO_0030705, obo:GO_0099111, [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0010971 obo:IAO_0000115 "Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:16:34Z" ; oboInOwl:hasAlternativeId "GO:0031662" ; oboInOwl:hasExactSynonym "positive regulation of mitotic entry" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle" ; oboInOwl:id "GO:0010971" ; a owl:Class ; rdfs:label "positive regulation of G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0010389, obo:GO_1901992, obo:GO_1902751, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000086 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000086 ] ) ] . obo:GO_0010972 obo:IAO_0000115 "Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:18:29Z" ; oboInOwl:hasExactSynonym "negative regulation of mitotic entry" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010972" ; a owl:Class ; rdfs:label "negative regulation of G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0010389, obo:GO_1901991, obo:GO_1902750, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000086 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000086 ] ) ] . obo:GO_0010975 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:44:45Z" ; oboInOwl:hasNarrowSynonym "regulation of neurite biosynthesis", "regulation of neurite development", "regulation of neurite formation", "regulation of neurite growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010975" ; a owl:Class ; rdfs:label "regulation of neuron projection development" ; rdfs:subClassOf obo:GO_0120035, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031175 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031175 ] ) ] . obo:GO_0010976 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:46:44Z" ; oboInOwl:hasNarrowSynonym "positive regulation of neurite biosynthesis", "positive regulation of neurite development", "positive regulation of neurite formation", "positive regulation of neurite growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010976" ; a owl:Class ; rdfs:label "positive regulation of neuron projection development" ; rdfs:subClassOf obo:GO_0010975, obo:GO_0031346, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031175 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031175 ] ) ] . obo:GO_0010977 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:47:42Z" ; oboInOwl:hasNarrowSynonym "negative regulation of neurite biosynthesis", "negative regulation of neurite development", "negative regulation of neurite formation", "negative regulation of neurite growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "growth cone collapse" ; oboInOwl:id "GO:0010977" ; a owl:Class ; rdfs:label "negative regulation of neuron projection development" ; rdfs:subClassOf obo:GO_0010975, obo:GO_0031345, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031175 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031175 ] ) ] . obo:GO_0012501 obo:IAO_0000115 "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24835"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0016244" ; oboInOwl:hasBroadSynonym "regulated cell death" ; oboInOwl:hasDbXref "Wikipedia:Programmed_cell_death" ; oboInOwl:hasNarrowSynonym "caspase-independent cell death", "non-apoptotic programmed cell death", "nonapoptotic programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "PCD", "RCD", "caspase-independent apoptosis" ; oboInOwl:id "GO:0012501" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_plant, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children." ; rdfs:label "programmed cell death" ; rdfs:subClassOf obo:GO_0008219, [ a owl:Restriction ; owl:onProperty obo:RO_0002224 ; owl:someValuesFrom obo:GO_0007165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008219 [ a owl:Restriction ; owl:onProperty obo:RO_0002224 ; owl:someValuesFrom obo:GO_0007165 ] ) ] . obo:GO_0012505 obo:IAO_0000115 "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." ; oboInOwl:hasDbXref "Wikipedia:Endomembrane_system" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0012505" ; oboInOwl:inSubset go:goslim_candida, go:goslim_flybase_ribbon, go:goslim_yeast ; a owl:Class ; rdfs:label "endomembrane system" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000000 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005773 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005886 ] . obo:GO_0012506 obo:IAO_0000115 "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1153182838" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0012506" ; a owl:Class ; rdfs:label "vesicle membrane" ; rdfs:subClassOf obo:GO_0031090, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031982 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0014009 obo:IAO_0000115 "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others." ; oboInOwl:hasExactSynonym "glia proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014009" ; a owl:Class ; rdfs:label "glial cell proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042063 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000125 ] ) ] . obo:GO_0014013 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014013" ; a owl:Class ; rdfs:label "regulation of gliogenesis" ; rdfs:subClassOf obo:GO_0050767, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042063 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042063 ] ) ] . obo:GO_0014014 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia." ; oboInOwl:hasExactSynonym "down regulation of gliogenesis", "down-regulation of gliogenesis", "downregulation of gliogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of gliogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014014" ; a owl:Class ; rdfs:label "negative regulation of gliogenesis" ; rdfs:subClassOf obo:GO_0014013, obo:GO_0050768, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042063 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042063 ] ) ] . obo:GO_0014015 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia." ; oboInOwl:hasExactSynonym "up regulation of gliogenesis", "up-regulation of gliogenesis", "upregulation of gliogenesis" ; oboInOwl:hasNarrowSynonym "activation of gliogenesis", "stimulation of gliogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014015" ; a owl:Class ; rdfs:label "positive regulation of gliogenesis" ; rdfs:subClassOf obo:GO_0014013, obo:GO_0050769, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042063 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042063 ] ) ] . obo:GO_0014016 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014016" ; a owl:Class ; rdfs:label "neuroblast differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048699 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000031 ] ) ] . obo:GO_0014019 obo:IAO_0000115 "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014019" ; a owl:Class ; rdfs:label "neuroblast development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0014016 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000031 ] ) ] . obo:GO_0014020 obo:IAO_0000115 "The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube." ; oboInOwl:hasAlternativeId "GO:0014024" ; oboInOwl:hasExactSynonym "primary neural tube morphogenesis", "primary neurulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neural rod cavitation" ; oboInOwl:id "GO:0014020" ; a owl:Class ; rdfs:label "primary neural tube formation" ; rdfs:subClassOf obo:GO_0001838, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001841 ] . obo:GO_0014023 obo:IAO_0000115 "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014023" ; a owl:Class ; rdfs:label "neural rod formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0014020 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_32443 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005068 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_32443 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005068 ] ) ] . obo:GO_0014025 obo:IAO_0000115 "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014025" ; a owl:Class ; rdfs:label "neural keel formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0014023 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0007135 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0007135 ] ) ] . obo:GO_0014028 obo:IAO_0000115 "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014028" ; a owl:Class ; rdfs:label "notochord formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048570 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002328 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002328 ] ) ] . obo:GO_0014029 obo:IAO_0000115 "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014029" ; a owl:Class ; rdfs:label "neural crest formation" ; rdfs:subClassOf obo:GO_0001837, obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043009 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002342 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002342 ] ) ] . obo:GO_0014031 obo:IAO_0000115 "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014031" ; a owl:Class ; rdfs:label "mesenchymal cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048762 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0008019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0008019 ] ) ] . obo:GO_0014032 obo:IAO_0000115 "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014032" ; a owl:Class ; rdfs:label "neural crest cell development" ; rdfs:subClassOf obo:GO_0048864, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0014033 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0011012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0011012 ] ) ] . obo:GO_0014033 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014033" ; a owl:Class ; rdfs:label "neural crest cell differentiation" ; rdfs:subClassOf obo:GO_0048762, obo:GO_0048863, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000333 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000333 ] ) ] . obo:GO_0014041 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014041" ; a owl:Class ; rdfs:label "regulation of neuron maturation" ; rdfs:subClassOf obo:GO_0045664, obo:GO_1903429, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042551 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042551 ] ) ] . obo:GO_0014042 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of neuron maturation." ; oboInOwl:hasExactSynonym "up regulation of neuron maturation", "up-regulation of neuron maturation", "upregulation of neuron maturation" ; oboInOwl:hasNarrowSynonym "activation of neuron maturation", "stimulation of neuron maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014042" ; a owl:Class ; rdfs:label "positive regulation of neuron maturation" ; rdfs:subClassOf obo:GO_0014041, obo:GO_1903431, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042551 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042551 ] ) ] . obo:GO_0014043 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." ; oboInOwl:hasExactSynonym "down regulation of neuron maturation", "down-regulation of neuron maturation", "downregulation of neuron maturation" ; oboInOwl:hasNarrowSynonym "inhibition of neuron maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014043" ; a owl:Class ; rdfs:label "negative regulation of neuron maturation" ; rdfs:subClassOf obo:GO_0014041, obo:GO_1903430, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042551 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042551 ] ) ] . obo:GO_0014046 obo:IAO_0000115 "The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014046" ; a owl:Class ; rdfs:label "dopamine secretion" ; rdfs:subClassOf obo:GO_0015872, obo:GO_0023061 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59905 ] ) ] . obo:GO_0014051 obo:IAO_0000115 "The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues." ; oboInOwl:hasExactSynonym "GABA secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014051" ; a owl:Class ; rdfs:label "gamma-aminobutyric acid secretion" ; rdfs:subClassOf obo:GO_0015812, obo:GO_0046717 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59888 ] ) ] . obo:GO_0014052 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." ; oboInOwl:hasExactSynonym "regulation of GABA secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014052" ; a owl:Class ; rdfs:label "regulation of gamma-aminobutyric acid secretion" ; rdfs:subClassOf obo:GO_0051046, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014051 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014051 ] ) ] . obo:GO_0014053 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." ; oboInOwl:hasExactSynonym "down regulation of gamma-aminobutyric acid secretion", "down-regulation of gamma-aminobutyric acid secretion", "downregulation of gamma-aminobutyric acid secretion", "negative regulation of GABA secretion" ; oboInOwl:hasNarrowSynonym "inhibition of gamma-aminobutyric acid secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014053" ; a owl:Class ; rdfs:label "negative regulation of gamma-aminobutyric acid secretion" ; rdfs:subClassOf obo:GO_0014052, obo:GO_0051048, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014051 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014051 ] ) ] . obo:GO_0014054 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid." ; oboInOwl:hasExactSynonym "positive regulation of GABA secretion", "up regulation of gamma-aminobutyric acid secretion", "up-regulation of gamma-aminobutyric acid secretion", "upregulation of gamma-aminobutyric acid secretion" ; oboInOwl:hasNarrowSynonym "activation of gamma-aminobutyric acid secretion", "stimulation of gamma-aminobutyric acid secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014054" ; a owl:Class ; rdfs:label "positive regulation of gamma-aminobutyric acid secretion" ; rdfs:subClassOf obo:GO_0014052, obo:GO_0051047, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014051 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014051 ] ) ] . obo:GO_0014055 obo:IAO_0000115 "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014055" ; a owl:Class ; rdfs:label "acetylcholine secretion, neurotransmission" ; rdfs:subClassOf obo:GO_0007269, obo:GO_0061526, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061526 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007271 ] ) ] . obo:GO_0014056 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014056" ; a owl:Class ; rdfs:label "regulation of acetylcholine secretion, neurotransmission" ; rdfs:subClassOf obo:GO_0032222, obo:GO_0046928, obo:GO_0051952, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014055 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014055 ] ) ] . obo:GO_0014057 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine." ; oboInOwl:hasExactSynonym "up regulation of acetylcholine secretion", "up-regulation of acetylcholine secretion", "upregulation of acetylcholine secretion" ; oboInOwl:hasNarrowSynonym "activation of acetylcholine secretion", "stimulation of acetylcholine secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014057" ; a owl:Class ; rdfs:label "positive regulation of acetylcholine secretion, neurotransmission" ; rdfs:subClassOf obo:GO_0001956, obo:GO_0014056, obo:GO_0032224, obo:GO_0051954, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014055 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014055 ] ) ] . obo:GO_0014058 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine." ; oboInOwl:hasExactSynonym "down regulation of acetylcholine secretion", "down-regulation of acetylcholine secretion", "downregulation of acetylcholine secretion" ; oboInOwl:hasNarrowSynonym "inhibition of acetylcholine secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014058" ; a owl:Class ; rdfs:label "negative regulation of acetylcholine secretion, neurotransmission" ; rdfs:subClassOf obo:GO_0014056, obo:GO_0032223, obo:GO_0046929, obo:GO_0051953, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014055 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014055 ] ) ] . obo:GO_0014059 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of dopamine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014059" ; a owl:Class ; rdfs:label "regulation of dopamine secretion" ; rdfs:subClassOf obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014046 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014046 ] ) ] . obo:GO_0014061 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine." ; oboInOwl:hasExactSynonym "regulation of noradrenaline secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014061" ; a owl:Class ; rdfs:label "regulation of norepinephrine secretion" ; rdfs:subClassOf obo:GO_0050433, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048243 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048243 ] ) ] . obo:GO_0014062 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of serotonin." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of serotonin release" ; oboInOwl:id "GO:0014062" ; a owl:Class ; rdfs:label "regulation of serotonin secretion" ; rdfs:subClassOf obo:GO_0043269, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001820 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001820 ] ) ] . obo:GO_0014063 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin." ; oboInOwl:hasExactSynonym "down regulation of serotonin secretion", "down-regulation of serotonin secretion", "downregulation of serotonin secretion" ; oboInOwl:hasNarrowSynonym "inhibition of serotonin secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of serotonin release" ; oboInOwl:id "GO:0014063" ; a owl:Class ; rdfs:label "negative regulation of serotonin secretion" ; rdfs:subClassOf obo:GO_0014062, obo:GO_0043271, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001820 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001820 ] ) ] . obo:GO_0014064 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin." ; oboInOwl:hasExactSynonym "up regulation of serotonin secretion", "up-regulation of serotonin secretion", "upregulation of serotonin secretion" ; oboInOwl:hasNarrowSynonym "activation of serotonin secretion", "stimulation of serotonin secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of serotonin release" ; oboInOwl:id "GO:0014064" ; a owl:Class ; rdfs:label "positive regulation of serotonin secretion" ; rdfs:subClassOf obo:GO_0014062, obo:GO_0043270, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001820 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001820 ] ) ] . obo:GO_0014070 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." ; oboInOwl:hasExactSynonym "response to organic cyclic substance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014070" ; a owl:Class ; rdfs:label "response to organic cyclic compound" ; rdfs:subClassOf obo:GO_0010033, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33832 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33832 ] ) ] . obo:GO_0014075 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." ; oboInOwl:hasExactSynonym "response to amine stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014075" ; a owl:Class ; rdfs:label "response to amine" ; rdfs:subClassOf obo:GO_0010243, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_32952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_32952 ] ) ] . obo:GO_0014076 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to SSRI", "response to selective serotonin reuptake inhibitor" ; oboInOwl:id "GO:0014076" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to fluoxetine" ; rdfs:subClassOf obo:GO_0036276 . obo:GO_0014706 obo:IAO_0000115 "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014706" ; a owl:Class ; rdfs:label "striated muscle tissue development" ; rdfs:subClassOf obo:GO_0060537, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002036 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002036 ] ) ] . obo:GO_0014722 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction." ; oboInOwl:hasExactSynonym "regulation of skeletal muscle contraction by calcium ion signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014722" ; a owl:Class ; rdfs:label "regulation of skeletal muscle contraction by calcium ion signaling" ; rdfs:subClassOf obo:GO_0014819, obo:GO_0019722 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019722 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003009 ] ) ] . obo:GO_0014733 obo:IAO_0000115 "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of skeletal muscle plasticity" ; oboInOwl:id "GO:0014733" ; a owl:Class ; rdfs:label "regulation of skeletal muscle adaptation" ; rdfs:subClassOf obo:GO_0043502, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043501 ] ) ] . obo:GO_0014734 obo:IAO_0000115 "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014734" ; a owl:Class ; rdfs:label "skeletal muscle hypertrophy" ; rdfs:subClassOf obo:GO_0014897, obo:GO_0043501 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0014896 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001134 ] ) ] . obo:GO_0014741 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014741" ; a owl:Class ; rdfs:label "negative regulation of muscle hypertrophy" ; rdfs:subClassOf obo:GO_0014743, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014896 ] ) ] . obo:GO_0014742 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014742" ; a owl:Class ; rdfs:label "positive regulation of muscle hypertrophy" ; rdfs:subClassOf obo:GO_0014743, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014896 ] ) ] . obo:GO_0014743 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of muscle hypertrophy." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014743" ; a owl:Class ; rdfs:label "regulation of muscle hypertrophy" ; rdfs:subClassOf obo:GO_0090257, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014896 ] ) ] . obo:GO_0014744 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of muscle adaptation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of muscle plasticity" ; oboInOwl:id "GO:0014744" ; a owl:Class ; rdfs:label "positive regulation of muscle adaptation" ; rdfs:subClassOf obo:GO_0043502, obo:GO_0048584, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043500 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043500 ] ) ] . obo:GO_0014745 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of muscle plasticity" ; oboInOwl:id "GO:0014745" ; a owl:Class ; rdfs:label "negative regulation of muscle adaptation" ; rdfs:subClassOf obo:GO_0043502, obo:GO_0048585, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043500 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043500 ] ) ] . obo:GO_0014805 obo:IAO_0000115 "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "smooth muscle plasticity" ; oboInOwl:id "GO:0014805" ; a owl:Class ; rdfs:label "smooth muscle adaptation" ; rdfs:subClassOf obo:GO_0043500, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001135 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043500 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001135 ] ) ] . obo:GO_0014807 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of somitogenesis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014807" ; a owl:Class ; rdfs:label "regulation of somitogenesis" ; rdfs:subClassOf obo:GO_0022603, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001756 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001756 ] ) ] . obo:GO_0014812 obo:IAO_0000115 "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014812" ; a owl:Class ; rdfs:label "muscle cell migration" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000187 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:GO_0014819 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of skeletal muscle contraction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014819" ; a owl:Class ; rdfs:label "regulation of skeletal muscle contraction" ; rdfs:subClassOf obo:GO_0006942, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003009 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003009 ] ) ] . obo:GO_0014821 obo:IAO_0000115 "A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014821" ; a owl:Class ; rdfs:label "phasic smooth muscle contraction" ; rdfs:subClassOf obo:GO_0006939 . obo:GO_0014827 obo:IAO_0000115 "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014827" ; a owl:Class ; rdfs:label "intestine smooth muscle contraction" ; rdfs:subClassOf obo:GO_0014821, obo:GO_0014831 . obo:GO_0014831 obo:IAO_0000115 "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014831" ; a owl:Class ; rdfs:label "gastro-intestinal system smooth muscle contraction" ; rdfs:subClassOf obo:GO_0006939 . obo:GO_0014832 obo:IAO_0000115 "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract." ; obo:RO_0002161 obo:NCBITaxon_8782 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014832" ; a owl:Class ; rdfs:label "urinary bladder smooth muscle contraction" ; rdfs:subClassOf obo:GO_0014848, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_8782 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_8782 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_8782 ] . obo:GO_0014848 obo:IAO_0000115 "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014848" ; a owl:Class ; rdfs:label "urinary tract smooth muscle contraction" ; rdfs:subClassOf obo:GO_0006939 . obo:GO_0014849 obo:IAO_0000115 "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014849" ; a owl:Class ; rdfs:label "ureter smooth muscle contraction" ; rdfs:subClassOf obo:GO_0014821, obo:GO_0014848 . obo:GO_0014852 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014852" ; a owl:Class ; rdfs:label "regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction" ; rdfs:subClassOf obo:GO_0014819 . obo:GO_0014855 obo:IAO_0000115 "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014855" ; a owl:Class ; rdfs:label "striated muscle cell proliferation" ; rdfs:subClassOf obo:GO_0033002, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000737 ] ) ] . obo:GO_0014856 obo:IAO_0000115 "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014856" ; a owl:Class ; rdfs:label "skeletal muscle cell proliferation" ; rdfs:subClassOf obo:GO_0014855, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000188 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000188 ] ) ] . obo:GO_0014857 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014857" ; a owl:Class ; rdfs:label "regulation of skeletal muscle cell proliferation" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014856 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014856 ] ) ] . obo:GO_0014858 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014858" ; a owl:Class ; rdfs:label "positive regulation of skeletal muscle cell proliferation" ; rdfs:subClassOf obo:GO_0008284, obo:GO_0014857, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014856 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014856 ] ) ] . obo:GO_0014859 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014859" ; a owl:Class ; rdfs:label "negative regulation of skeletal muscle cell proliferation" ; rdfs:subClassOf obo:GO_0008285, obo:GO_0014857, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014856 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014856 ] ) ] . obo:GO_0014860 obo:IAO_0000115 "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." ; oboInOwl:hasExactSynonym "neurotransmitter secretion involved in control of skeletal muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014860" ; a owl:Class ; rdfs:label "neurotransmitter secretion involved in regulation of skeletal muscle contraction" ; rdfs:subClassOf obo:GO_0007269, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0014852 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007269 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0014819 ] ) ] . obo:GO_0014861 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of skeletal muscle contraction via membrane action potential" ; oboInOwl:id "GO:0014861" ; a owl:Class ; rdfs:label "regulation of skeletal muscle contraction via regulation of action potential" ; rdfs:subClassOf obo:GO_0014819, obo:GO_0098900, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0100001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050789 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0100001 ] ) ] . obo:GO_0014866 obo:IAO_0000115 "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014866" ; a owl:Class ; rdfs:label "skeletal myofibril assembly" ; rdfs:subClassOf obo:GO_0030239, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0098723 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0098723 ] ) ] . obo:GO_0014872 obo:IAO_0000115 "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014872" ; a owl:Class ; rdfs:label "myoblast division" ; rdfs:subClassOf obo:GO_0051301, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051301 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000056 ] ) ] . obo:GO_0014874 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to stimulus involved in regulation of muscle plasticity" ; oboInOwl:id "GO:0014874" ; a owl:Class ; rdfs:label "response to stimulus involved in regulation of muscle adaptation" ; rdfs:subClassOf obo:GO_0050896, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043502 ] ) ] . obo:GO_0014887 obo:IAO_0000115 "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiac muscle plasticity" ; oboInOwl:id "GO:0014887" ; a owl:Class ; rdfs:label "cardiac muscle adaptation" ; rdfs:subClassOf obo:GO_0014888, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043500 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001133 ] ) ] . obo:GO_0014888 obo:IAO_0000115 "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "striated muscle plasticity" ; oboInOwl:id "GO:0014888" ; a owl:Class ; rdfs:label "striated muscle adaptation" ; rdfs:subClassOf obo:GO_0043500, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002036 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043500 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002036 ] ) ] . obo:GO_0014895 obo:IAO_0000115 "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014895" ; a owl:Class ; rdfs:label "smooth muscle hypertrophy" ; rdfs:subClassOf obo:GO_0014805, obo:GO_0014896 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0014896 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001135 ] ) ] . obo:GO_0014896 obo:IAO_0000115 "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy." ; oboInOwl:hasDbXref "Wikipedia:Muscle_hypertrophy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014896" ; a owl:Class ; rdfs:label "muscle hypertrophy" ; rdfs:subClassOf obo:GO_0003012, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002385 ] . obo:GO_0014897 obo:IAO_0000115 "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014897" ; a owl:Class ; rdfs:label "striated muscle hypertrophy" ; rdfs:subClassOf obo:GO_0014896, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:UBERON_0002036 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0014896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:UBERON_0002036 ] ) ] . obo:GO_0014902 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014902" ; a owl:Class ; rdfs:label "myotube differentiation" ; rdfs:subClassOf obo:GO_0051146, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002372 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002372 ] ) ] . obo:GO_0014904 obo:IAO_0000115 "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014904" ; a owl:Class ; rdfs:label "myotube cell development" ; rdfs:subClassOf obo:GO_0055002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0014902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002372 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002372 ] ) ] . obo:GO_0014909 obo:IAO_0000115 "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014909" ; a owl:Class ; rdfs:label "smooth muscle cell migration" ; rdfs:subClassOf obo:GO_0014812, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000192 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000192 ] ) ] . obo:GO_0014910 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of smooth muscle cell migration." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014910" ; a owl:Class ; rdfs:label "regulation of smooth muscle cell migration" ; rdfs:subClassOf obo:GO_0030334, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014909 ] ) ] . obo:GO_0014911 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014911" ; a owl:Class ; rdfs:label "positive regulation of smooth muscle cell migration" ; rdfs:subClassOf obo:GO_0014910, obo:GO_0030335, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014909 ] ) ] . obo:GO_0014912 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014912" ; a owl:Class ; rdfs:label "negative regulation of smooth muscle cell migration" ; rdfs:subClassOf obo:GO_0014910, obo:GO_0030336, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014909 ] ) ] . obo:GO_0015031 obo:IAO_0000115 "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasAlternativeId "GO:0015831" ; oboInOwl:hasNarrowSynonym "enzyme transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015031" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "protein transport" ; rdfs:subClassOf obo:GO_0045184, obo:GO_0071702, obo:GO_0071705 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 _:genid18982 ) ] . obo:GO_0015075 obo:IAO_0000115 "Enables the transfer of an ion from one side of a membrane to the other." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24479"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "ion transmembrane transporter activity" ; oboInOwl:hasExactSynonym "ion transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015075" ; a owl:Class ; rdfs:label "monoatomic ion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, _:genid18982, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24867 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24867 ] ) ] . obo:GO_0015081 obo:IAO_0000115 "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24076"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0022816" ; oboInOwl:hasDbXref "RHEA:34963" ; oboInOwl:hasExactSynonym "sodium transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015081" ; a owl:Class ; rdfs:label "sodium ion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0046873, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035725 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29101 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29101 ] ) ] . obo:GO_0015085 obo:IAO_0000115 "Enables the transfer of calcium (Ca) ions from one side of a membrane to the other." ; oboInOwl:hasDbXref "RHEA:29671", "Reactome:R-HSA-2534359" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015085" ; a owl:Class ; rdfs:label "calcium ion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0046873, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070588 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29108 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29108 ] ) ] . obo:GO_0015101 obo:IAO_0000115 "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage." ; oboInOwl:hasDbXref "Reactome:R-HSA-2161500", "Reactome:R-HSA-549129", "Reactome:R-HSA-549279", "Reactome:R-HSA-549304", "Reactome:R-HSA-549322", "Reactome:R-HSA-561054", "Reactome:R-HSA-561072", "Reactome:R-HSA-9794270", "Reactome:R-HSA-9794523", "Reactome:R-HSA-9795207" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015101" ; a owl:Class ; rdfs:label "organic cation transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015695 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25697 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25697 ] ) ] . obo:GO_0015103 obo:IAO_0000115 "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015103" ; a owl:Class ; rdfs:label "inorganic anion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015318, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015698 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24834 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24834 ] ) ] . obo:GO_0015106 obo:IAO_0000115 "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-." ; oboInOwl:hasDbXref "RHEA:28695", "Reactome:R-HSA-2752067" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015106" ; a owl:Class ; rdfs:label "bicarbonate transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0008514, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015701 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17544 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17544 ] ) ] . obo:GO_0015114 obo:IAO_0000115 "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-22T15:43:10Z" ; oboInOwl:hasAlternativeId "GO:1901677" ; oboInOwl:hasDbXref "RHEA:32823" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "phosphate transmembrane transporter activity" ; oboInOwl:id "GO:0015114" ; a owl:Class ; rdfs:label "phosphate ion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015103, _:genid19037, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35780 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35780 ] ) ] . obo:GO_0015116 obo:IAO_0000115 "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other." ; oboInOwl:hasDbXref "RHEA:34983", "Reactome:R-HSA-3560789", "Reactome:R-HSA-427555", "Reactome:R-HSA-8875871" ; oboInOwl:hasExactSynonym "sulphate transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "sulfate permease activity" ; oboInOwl:id "GO:0015116" ; a owl:Class ; rdfs:label "sulfate transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015103, obo:GO_1901682, _:genid19046, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16189 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16189 ] ) ] . obo:GO_0015123 obo:IAO_0000115 "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015123" ; a owl:Class ; rdfs:label "acetate transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0046943, _:genid19057, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_30089 ] ; owl:equivalentClass _:genid19057 . obo:GO_0015125 obo:IAO_0000115 "Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine." ; oboInOwl:hasDbXref "Reactome:R-HSA-194079", "Reactome:R-HSA-194083", "Reactome:R-HSA-194130", "Reactome:R-HSA-5661184", "Reactome:R-HSA-5661198", "Reactome:R-HSA-9733964" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015125" ; a owl:Class ; rdfs:label "bile acid transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0005319, obo:GO_0008028, obo:GO_1901618, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015721 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_3098 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_3098 ] ) ] . obo:GO_0015127 obo:IAO_0000115 "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile." ; oboInOwl:hasDbXref "Reactome:R-HSA-5679031", "Reactome:R-HSA-5679041", "Reactome:R-HSA-9661417" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015127" ; a owl:Class ; rdfs:label "bilirubin transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0046943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015723 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_57977 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_57977 ] ) ] . obo:GO_0015144 obo:IAO_0000115 "Enables the transfer of carbohydrate from one side of a membrane to the other." ; oboInOwl:hasAlternativeId "GO:1901476" ; oboInOwl:hasNarrowSynonym "sugar transporter" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "carbohydrate transporter activity" ; oboInOwl:id "GO:0015144" ; a owl:Class ; rdfs:label "carbohydrate transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, _:genid19088, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16646 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf _:genid19088 ] . obo:GO_0015145 obo:IAO_0000115 "Enables the transfer of a monosaccharide from one side of a membrane to the other." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015145" ; a owl:Class ; rdfs:label "monosaccharide transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0051119, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015749 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35381 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35381 ] ) ] . obo:GO_0015149 obo:IAO_0000115 "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other." ; oboInOwl:hasDbXref "Reactome:R-HSA-189242", "Reactome:R-HSA-5638222" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015149" ; a owl:Class ; rdfs:label "hexose transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015145, _:genid19103, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 _:genid19103 ) ] . obo:GO_0015159 obo:IAO_0000115 "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015159" ; a owl:Class ; rdfs:label "polysaccharide transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015144, obo:GO_0022884, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015774 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18154 ] ) ] . obo:GO_0015171 obo:IAO_0000115 "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group." ; oboInOwl:hasAlternativeId "GO:0015359" ; oboInOwl:hasBroadSynonym "amino acid transporter activity" ; oboInOwl:hasDbXref "Reactome:R-HSA-210439", "Reactome:R-HSA-212642", "Reactome:R-HSA-351963", "Reactome:R-HSA-351987", "Reactome:R-HSA-352029", "Reactome:R-HSA-352052", "Reactome:R-HSA-352059", "Reactome:R-HSA-352103", "Reactome:R-HSA-352107", "Reactome:R-HSA-352108", "Reactome:R-HSA-352119", "Reactome:R-HSA-352136", "Reactome:R-HSA-352158", "Reactome:R-HSA-352174", "Reactome:R-HSA-352182", "Reactome:R-HSA-352191", "Reactome:R-HSA-352232", "Reactome:R-HSA-352347", "Reactome:R-HSA-352354", "Reactome:R-HSA-352364", "Reactome:R-HSA-352371", "Reactome:R-HSA-352379", "Reactome:R-HSA-352385", "Reactome:R-HSA-375405", "Reactome:R-HSA-375417", "Reactome:R-HSA-375473", "Reactome:R-HSA-375487", "Reactome:R-HSA-375768", "Reactome:R-HSA-375770", "Reactome:R-HSA-375776", "Reactome:R-HSA-375790", "Reactome:R-HSA-376200", "Reactome:R-HSA-378513", "Reactome:R-HSA-379415", "Reactome:R-HSA-379426", "Reactome:R-HSA-379432", "Reactome:R-HSA-5653850", "Reactome:R-HSA-5655702", "Reactome:R-HSA-5659674", "Reactome:R-HSA-5659734", "Reactome:R-HSA-5659755", "Reactome:R-HSA-5660694", "Reactome:R-HSA-5660890", "Reactome:R-HSA-5660910", "Reactome:R-HSA-888592", "Reactome:R-HSA-8952726" ; oboInOwl:hasExactSynonym "amino acid permease activity" ; oboInOwl:hasNarrowSynonym "amino acid/choline transmembrane transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "general amino acid permease activity", "hydroxy/aromatic amino acid permease activity" ; oboInOwl:id "GO:0015171" ; a owl:Class ; rdfs:label "amino acid transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0005342, _:genid19120, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33709 ] ) ] . obo:GO_0015185 obo:IAO_0000115 "Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA)." ; oboInOwl:hasExactSynonym "4-aminobutanoate transporter activity", "4-aminobutyrate transporter activity", "GABA transporter activity" ; oboInOwl:hasNarrowSynonym "betaine/GABA:sodium symporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015185" ; a owl:Class ; rdfs:label "gamma-aminobutyric acid transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015812 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59888 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59888 ] ) ] . obo:GO_0015205 obo:IAO_0000115 "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other." ; oboInOwl:hasAlternativeId "GO:0015392" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015205" ; a owl:Class ; rdfs:label "nucleobase transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015851 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18282 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18282 ] ) ] . obo:GO_0015318 obo:IAO_0000115 "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14372"^^xsd:anyURI ; oboInOwl:hasExactSynonym "inorganic solute uptake transmembrane transporter activity", "inorganic uptake permease activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015318" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "inorganic molecular entity transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24835 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24835 ] ) ] . obo:GO_0015629 obo:IAO_0000115 "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0015629" ; a owl:Class ; rdfs:label "actin cytoskeleton" ; rdfs:subClassOf obo:GO_0005856 . obo:GO_0015630 obo:IAO_0000115 "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0015630" ; a owl:Class ; rdfs:label "microtubule cytoskeleton" ; rdfs:subClassOf obo:GO_0005856 . obo:GO_0015631 obo:IAO_0000115 "Binding to monomeric or multimeric forms of tubulin, including microtubules." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0015631" ; a owl:Class ; rdfs:label "tubulin binding" ; rdfs:subClassOf obo:GO_0008092 . obo:GO_0015669 obo:IAO_0000115 "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015669" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "gas transport" ; rdfs:subClassOf obo:GO_0006810 . obo:GO_0015671 obo:IAO_0000115 "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015671" ; a owl:Class ; rdfs:label "oxygen transport" ; rdfs:subClassOf obo:GO_0015669, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15379 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15379 ] ) ] . obo:GO_0015695 obo:IAO_0000115 "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015695" ; a owl:Class ; rdfs:label "organic cation transport" ; rdfs:subClassOf obo:GO_0071702, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25697 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25697 ] ) ] . obo:GO_0015698 obo:IAO_0000115 "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015698" ; a owl:Class ; rdfs:label "inorganic anion transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24834 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24834 ] ) ] . obo:GO_0015701 obo:IAO_0000115 "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015701" ; a owl:Class ; rdfs:label "bicarbonate transport" ; rdfs:subClassOf obo:GO_0015711, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17544 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17544 ] ) ] . obo:GO_0015711 obo:IAO_0000115 "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015711" ; a owl:Class ; rdfs:label "organic anion transport" ; rdfs:subClassOf obo:GO_0071702, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25696 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25696 ] ) ] . obo:GO_0015718 obo:IAO_0000115 "The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015718" ; a owl:Class ; rdfs:label "monocarboxylic acid transport" ; rdfs:subClassOf obo:GO_0046942, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35757 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35757 ] ) ] . obo:GO_0015721 obo:IAO_0000115 "The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasNarrowSynonym "bile acid transport", "bile salt transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015721" ; a owl:Class ; rdfs:label "bile acid and bile salt transport" ; rdfs:subClassOf obo:GO_0006869, obo:GO_0015718, obo:GO_0015849, obo:GO_0015850, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_3098 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_3098 ] ) ] . obo:GO_0015723 obo:IAO_0000115 "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015723" ; a owl:Class ; rdfs:label "bilirubin transport" ; rdfs:subClassOf obo:GO_0006835, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_57977 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_57977 ] ) ] . obo:GO_0015749 obo:IAO_0000115 "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2017-02-19T10:41:27Z" ; oboInOwl:hasAlternativeId "GO:1905950" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "monosaccharide transport" ; oboInOwl:id "GO:0015749" ; a owl:Class ; rdfs:label "monosaccharide transmembrane transport" ; rdfs:subClassOf obo:GO_0034219, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35381 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35381 ] ) ] . obo:GO_0015774 obo:IAO_0000115 "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015774" ; a owl:Class ; rdfs:label "polysaccharide transport" ; rdfs:subClassOf obo:GO_0008643, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033037 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18154 ] ) ] . obo:GO_0015812 obo:IAO_0000115 "The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "4-aminobutanoate transport", "4-aminobutyrate transport", "GABA transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015812" ; a owl:Class ; rdfs:comment "See also the biological process term 'neurotransmitter transport ; GO:0006836'." ; rdfs:label "gamma-aminobutyric acid transport" ; rdfs:subClassOf obo:GO_0071702, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59888 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59888 ] ) ] . obo:GO_0015833 obo:IAO_0000115 "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015833" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "peptide transport" ; rdfs:subClassOf obo:GO_0042886, obo:GO_0071702, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16670 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0015837 obo:IAO_0000115 "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "amine/polyamine transport" ; oboInOwl:id "GO:0015837" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "amine transport" ; rdfs:subClassOf obo:GO_0071702, obo:GO_0071705, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32952 ] ) ] . obo:GO_0015844 obo:IAO_0000115 "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasAlternativeId "GO:0015873" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015844" ; a owl:Class ; rdfs:label "monoamine transport" ; rdfs:subClassOf obo:GO_0071702, obo:GO_0071705, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_63534 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_63534 ] ) ] . obo:GO_0015849 obo:IAO_0000115 "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015849" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "organic acid transport" ; rdfs:subClassOf obo:GO_0071702, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64709 ] ) ] . obo:GO_0015850 obo:IAO_0000115 "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom." ; oboInOwl:hasExactSynonym "organic alcohol transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015850" ; a owl:Class ; rdfs:label "organic hydroxy compound transport" ; rdfs:subClassOf obo:GO_0071702, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33822 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33822 ] ) ] . obo:GO_0015851 obo:IAO_0000115 "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "nucleobase transmembrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015851" ; a owl:Class ; rdfs:label "nucleobase transport" ; rdfs:subClassOf obo:GO_0071702, obo:GO_0071705, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18282 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18282 ] ) ] . obo:GO_0015869 obo:IAO_0000115 "The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "DNA-protein complex transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015869" ; a owl:Class ; rdfs:label "protein-DNA complex transport" ; rdfs:subClassOf obo:GO_0006886, obo:GO_0015931, obo:GO_0031503, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0032993 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0032993 ] ) ] . obo:GO_0015870 obo:IAO_0000115 "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015870" ; a owl:Class ; rdfs:label "acetylcholine transport" ; rdfs:subClassOf obo:GO_0015695, obo:GO_0071705, obo:GO_1901374, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15355 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15355 ] ) ] . obo:GO_0015872 obo:IAO_0000115 "The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015872" ; a owl:Class ; rdfs:label "dopamine transport" ; rdfs:subClassOf obo:GO_0071705, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59905 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59905 ] ) ] . obo:GO_0015874 obo:IAO_0000115 "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." ; oboInOwl:hasExactSynonym "levarterenol transport", "noradrenaline transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015874" ; a owl:Class ; rdfs:label "norepinephrine transport" ; rdfs:subClassOf obo:GO_0015695, obo:GO_0051937, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_72587 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0015931 obo:IAO_0000115 "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:id "GO:0015931" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "nucleobase-containing compound transport" ; rdfs:subClassOf obo:GO_0071702, obo:GO_0071705, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_61120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_61120 ] ) ] . obo:GO_0015932 obo:IAO_0000115 "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity" ; oboInOwl:id "GO:0015932" ; a owl:Class ; rdfs:label "nucleobase-containing compound transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015931 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_61120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_61120 ] ) ] . obo:GO_0015980 obo:IAO_0000115 "The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released." ; oboInOwl:hasExactSynonym "chemoorganotrophy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015980" ; a owl:Class ; rdfs:label "energy derivation by oxidation of organic compounds" ; rdfs:subClassOf obo:GO_0006091 . obo:GO_0016020 obo:IAO_0000115 "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." ; oboInOwl:creation_date "2014-03-06T11:37:54Z" ; oboInOwl:hasAlternativeId "GO:0016021", "GO:0098589", "GO:0098805" ; oboInOwl:hasDbXref "Wikipedia:Biological_membrane", "Wikipedia:Transmembrane_protein" ; oboInOwl:hasNarrowSynonym "integral component of membrane", "integral to membrane", "membrane region", "region of membrane", "whole membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "transmembrane" ; oboInOwl:id "GO:0016020" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "membrane" ; rdfs:subClassOf obo:GO_0110165 ; owl:disjointWith obo:GO_0031012 . obo:GO_0016042 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." ; oboInOwl:hasAlternativeId "GO:0006724", "GO:0044240" ; oboInOwl:hasDbXref "Wikipedia:Lipid_catabolism" ; oboInOwl:hasExactSynonym "lipid breakdown", "lipid catabolism", "lipid degradation", "lipolysis" ; oboInOwl:hasNarrowSynonym "multicellular organism lipid catabolic process", "multicellular organismal lipid catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016042" ; a owl:Class ; rdfs:label "lipid catabolic process" ; rdfs:subClassOf obo:GO_0006629, obo:GO_1901575, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0016043 obo:IAO_0000115 "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." ; oboInOwl:hasAlternativeId "GO:0044235", "GO:0071842" ; oboInOwl:hasExactSynonym "cell organisation", "cellular component organisation at cellular level", "cellular component organisation in other organism", "cellular component organization at cellular level", "cellular component organization in other organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell organization and biogenesis" ; oboInOwl:id "GO:0016043" ; oboInOwl:inSubset go:goslim_agr, go:goslim_mouse, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "cellular component organization" ; rdfs:subClassOf obo:GO_0071840, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005575 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005575 ] ) ] . obo:GO_0016049 obo:IAO_0000115 "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." ; oboInOwl:hasAlternativeId "GO:0048591" ; oboInOwl:hasExactSynonym "cellular growth", "growth of cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell expansion", "metabolic process resulting in cell growth", "metabolism resulting in cell growth", "non-developmental cell growth", "non-developmental growth of a unicellular organism" ; oboInOwl:id "GO:0016049" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_drosophila, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "cell growth" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0040007, [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:CL_0000000 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040007 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:CL_0000000 ] ) ] . obo:GO_0016050 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." ; oboInOwl:hasExactSynonym "vesicle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "vesicle organization and biogenesis" ; oboInOwl:id "GO:0016050" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "vesicle organization" ; rdfs:subClassOf obo:GO_0006996, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031982 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0016051 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." ; oboInOwl:hasAlternativeId "GO:0006093" ; oboInOwl:hasExactSynonym "anabolic carbohydrate metabolic process", "anabolic carbohydrate metabolism", "carbohydrate anabolism", "carbohydrate biosynthesis", "carbohydrate formation", "carbohydrate synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016051" ; a owl:Class ; rdfs:label "carbohydrate biosynthetic process" ; rdfs:subClassOf obo:GO_0005975, obo:GO_1901576, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16646 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16646 ] ) ] . obo:GO_0016052 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-10-23T16:34:39Z" ; oboInOwl:hasAlternativeId "GO:0006095", "GO:0044276", "GO:0044724" ; oboInOwl:hasExactSynonym "carbohydrate breakdown", "carbohydrate catabolism", "carbohydrate degradation", "catabolic carbohydrate metabolic process", "catabolic carbohydrate metabolism" ; oboInOwl:hasNarrowSynonym "multicellular organismal carbohydrate catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism carbohydrate catabolic process" ; oboInOwl:id "GO:0016052" ; a owl:Class ; rdfs:label "carbohydrate catabolic process" ; rdfs:subClassOf obo:GO_0005975, obo:GO_1901575, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16646 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16646 ] ) ] . obo:GO_0016053 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage." ; oboInOwl:hasExactSynonym "organic acid anabolism", "organic acid biosynthesis", "organic acid formation", "organic acid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016053" ; a owl:Class ; rdfs:label "organic acid biosynthetic process" ; rdfs:subClassOf obo:GO_0006082, obo:GO_0044249, obo:GO_0044283, obo:GO_1901576, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_64709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_64709 ] ) ] . obo:GO_0016054 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage." ; oboInOwl:hasExactSynonym "organic acid breakdown", "organic acid catabolism", "organic acid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016054" ; a owl:Class ; rdfs:label "organic acid catabolic process" ; rdfs:subClassOf obo:GO_0006082, obo:GO_0044248, obo:GO_0044282, obo:GO_1901575, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64709 ] ) ] . obo:GO_0016057 obo:IAO_0000115 "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon." ; oboInOwl:hasExactSynonym "changes in polarization state of photoreceptor cell membrane" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016057" ; a owl:Class ; rdfs:label "regulation of membrane potential in photoreceptor cell" ; rdfs:subClassOf obo:GO_0042391, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000210 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042391 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000210 ] ) ] . obo:GO_0016070 obo:IAO_0000115 "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; oboInOwl:hasExactSynonym "RNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016070" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_metagenomics, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "RNA metabolic process" ; rdfs:subClassOf obo:GO_0090304, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33697 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33697 ] ) ] . obo:GO_0016071 obo:IAO_0000115 "The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." ; oboInOwl:hasExactSynonym "mRNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016071" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "mRNA metabolic process" ; rdfs:subClassOf obo:GO_0016070 . obo:GO_0016079 obo:IAO_0000115 "Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016079" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle exocytosis" ; rdfs:subClassOf obo:GO_0045055, obo:GO_0051649, obo:GO_0099003, obo:GO_0099643, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007269 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099504 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045055 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0016192 obo:IAO_0000115 "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." ; oboInOwl:hasAlternativeId "GO:0006899" ; oboInOwl:hasExactSynonym "vesicle transport", "vesicular transport" ; oboInOwl:hasNarrowSynonym "nonselective vesicle transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein sorting along secretory pathway", "vesicle trafficking" ; oboInOwl:id "GO:0016192" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe ; a owl:Class ; rdfs:label "vesicle-mediated transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0031982 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0016202 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of striated muscle development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016202" ; a owl:Class ; rdfs:label "regulation of striated muscle tissue development" ; rdfs:subClassOf obo:GO_0048634, obo:GO_1901861, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014706 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014706 ] ) ] . obo:GO_0016203 obo:IAO_0000115 "The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016203" ; a owl:Class ; rdfs:label "muscle attachment" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060538 ] . obo:GO_0016236 obo:IAO_0000115 "The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded." ; oboInOwl:hasAlternativeId "GO:0034262" ; oboInOwl:hasBroadSynonym "autophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016236" ; a owl:Class ; rdfs:comment "Targeted macroautophagy sometimes targets regions of cytoplasm containing non-self, such as virus particles or components (e.g. see PMID:20159618). As this is essentially the same process as macroautophagy that encloses and digests only self, the term autophagy is still used despite the enclosure of some non-self (non-auto) entities." ; rdfs:label "macroautophagy" ; rdfs:subClassOf obo:GO_0006914 . obo:GO_0016239 obo:IAO_0000115 "Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation." ; oboInOwl:hasExactSynonym "positive regulation of starvation-induced autophagy", "up regulation of macroautophagy", "up-regulation of macroautophagy", "upregulation of macroautophagy" ; oboInOwl:hasNarrowSynonym "activation of macroautophagy", "stimulation of macroautophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016239" ; a owl:Class ; rdfs:label "positive regulation of macroautophagy" ; rdfs:subClassOf obo:GO_0010508, obo:GO_0016241, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016236 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016236 ] ) ] . obo:GO_0016241 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of macroautophagy." ; oboInOwl:hasExactSynonym "regulation of starvation-induced autophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016241" ; a owl:Class ; rdfs:label "regulation of macroautophagy" ; rdfs:subClassOf obo:GO_0010506, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016236 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016236 ] ) ] . obo:GO_0016242 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy." ; oboInOwl:hasExactSynonym "down regulation of macroautophagy", "down-regulation of macroautophagy", "downregulation of macroautophagy", "negative regulation of starvation-induced autophagy" ; oboInOwl:hasNarrowSynonym "inhibition of macroautophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016242" ; a owl:Class ; rdfs:label "negative regulation of macroautophagy" ; rdfs:subClassOf obo:GO_0010507, obo:GO_0016241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016236 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016236 ] ) ] . obo:GO_0016246 obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:GO_0035194 ; a owl:Class ; owl:deprecated true . obo:GO_0016301 obo:IAO_0000115 "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ; oboInOwl:hasDbXref "Reactome:R-HSA-6788855", "Reactome:R-HSA-6788867" ; oboInOwl:hasExactSynonym "phosphokinase activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016301" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_metagenomics, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term." ; rdfs:label "kinase activity" ; rdfs:subClassOf obo:GO_0016772, [ a owl:Restriction ; owl:hasSelf true ; owl:onProperty obo:RO_0002481 ] . obo:GO_0016310 obo:IAO_0000115 "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." ; oboInOwl:hasDbXref "Wikipedia:Phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016310" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_metagenomics ; a owl:Class ; rdfs:label "phosphorylation" ; rdfs:subClassOf obo:GO_0006796 . obo:GO_0016321 obo:IAO_0000115 "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016321" ; a owl:Class ; rdfs:label "female meiosis chromosome segregation" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0045132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098813 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ) ] . obo:GO_0016325 obo:IAO_0000115 "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0048130" ; oboInOwl:hasExactSynonym "oocyte microtubule cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016325" ; a owl:Class ; rdfs:label "oocyte microtubule cytoskeleton organization" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0030951, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007308 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000023 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0015630 ] ) ] . obo:GO_0016331 obo:IAO_0000115 "The process in which the anatomical structures of embryonic epithelia are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016331" ; a owl:Class ; rdfs:label "morphogenesis of embryonic epithelium" ; rdfs:subClassOf obo:GO_0002009, obo:GO_0048598 . obo:GO_0016358 obo:IAO_0000115 "The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016358" ; a owl:Class ; rdfs:label "dendrite development" ; rdfs:subClassOf obo:GO_0031175, obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:GO_0030425 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:GO_0030425 ] ) ] . obo:GO_0016459 obo:IAO_0000115 "A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0016459" ; a owl:Class ; rdfs:label "myosin complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015629 ] . obo:GO_0016460 obo:IAO_0000115 "A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "conventional myosin" ; oboInOwl:id "GO:0016460" ; a owl:Class ; rdfs:label "myosin II complex" ; rdfs:subClassOf obo:GO_0016459 . obo:GO_0016477 obo:IAO_0000115 "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24787"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Cell_migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016477" ; a owl:Class ; rdfs:label "cell migration" ; rdfs:subClassOf obo:GO_0048870 . obo:GO_0016482 obo:IAO_0000115 "The directed movement of substances or organelles within the cytosol." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016482" ; a owl:Class ; rdfs:label "cytosolic transport" ; rdfs:subClassOf obo:GO_0046907, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005829 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005829 ] ) ] . obo:GO_0016525 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis." ; oboInOwl:hasExactSynonym "down regulation of angiogenesis", "down-regulation of angiogenesis", "downregulation of angiogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of angiogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016525" ; a owl:Class ; rdfs:label "negative regulation of angiogenesis" ; rdfs:subClassOf obo:GO_0045765, obo:GO_2000181, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001525 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001525 ] ) ] . obo:GO_0016528 obo:IAO_0000115 "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "Wikipedia:Sarcoplasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0016528" ; a owl:Class ; rdfs:label "sarcoplasm" ; rdfs:subClassOf obo:GO_0005737, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:GO_0016740 obo:IAO_0000115 "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." ; oboInOwl:hasDbXref "EC:2.-.-.-", "Reactome:R-HSA-1483089", "Reactome:R-HSA-1483186", "Reactome:R-HSA-5668414", "Reactome:R-HSA-8868783" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016740" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "transferase activity" ; rdfs:subClassOf obo:GO_0003824 . obo:GO_0016757 obo:IAO_0000115 "Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor)." ; oboInOwl:hasAlternativeId "GO:0016932" ; oboInOwl:hasDbXref "EC:2.4.-.-", "Reactome:R-HSA-5173005", "Reactome:R-HSA-6785565" ; oboInOwl:hasExactSynonym "transferase activity, transferring glycosyl groups", "transglycosidase activity", "transglycosylase activity" ; oboInOwl:hasNarrowSynonym "transferase activity, transferring other glycosyl groups" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016757" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_yeast ; a owl:Class ; rdfs:label "glycosyltransferase activity" ; rdfs:subClassOf obo:GO_0016740 . obo:GO_0016772 obo:IAO_0000115 "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." ; oboInOwl:hasDbXref "EC:2.7.-.-" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016772" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:comment "Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides." ; rdfs:label "transferase activity, transferring phosphorus-containing groups" ; rdfs:subClassOf obo:GO_0016740 . obo:GO_0016787 obo:IAO_0000115 "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc." ; oboInOwl:hasDbXref "EC:3.-.-.-", "Reactome:R-HSA-1236938", "Reactome:R-HSA-2029475", "Reactome:R-HSA-5694583", "Reactome:R-HSA-5695964", "Reactome:R-HSA-6786190", "Reactome:R-HSA-6788295", "Reactome:R-HSA-8938314", "Reactome:R-HSA-8952137" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016787" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "hydrolase activity" ; rdfs:subClassOf obo:GO_0003824 . obo:GO_0016788 obo:IAO_0000115 "Catalysis of the hydrolysis of any ester bond." ; oboInOwl:hasDbXref "EC:3.1.-.-", "Reactome:R-HSA-162729", "Reactome:R-HSA-9023617", "Reactome:R-HSA-9023619", "Reactome:R-HSA-9749609" ; oboInOwl:hasExactSynonym "esterase activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016788" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "hydrolase activity, acting on ester bonds" ; rdfs:subClassOf obo:GO_0016787 . obo:GO_0017046 obo:IAO_0000115 "Binding to a peptide with hormonal activity in animals." ; oboInOwl:hasExactSynonym "polypeptide hormone binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0017046" ; a owl:Class ; rdfs:label "peptide hormone binding" ; rdfs:subClassOf obo:GO_0042277, obo:GO_0042562, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_25905 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_25905 ] ) ] . obo:GO_0017085 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "insecticide resistance", "insecticide susceptibility/resistance" ; oboInOwl:id "GO:0017085" ; a owl:Class ; rdfs:label "response to insecticide" ; rdfs:subClassOf obo:GO_0009636 . obo:GO_0017126 obo:IAO_0000115 "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells." ; oboInOwl:hasExactSynonym "nucleolus biogenesis" ; oboInOwl:hasNarrowSynonym "nucleolus assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0017126" ; a owl:Class ; rdfs:label "nucleologenesis" ; rdfs:subClassOf obo:GO_0007000, obo:GO_0044085, [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:GO_0005730 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044085 [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:GO_0005730 ] ) ] . obo:GO_0017145 obo:IAO_0000115 "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types." ; oboInOwl:hasExactSynonym "stem cell renewal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0017145" ; a owl:Class ; rdfs:label "stem cell division" ; rdfs:subClassOf obo:GO_0051301, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000034 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051301 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000034 ] ) ] . obo:GO_0017148 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ; oboInOwl:hasAlternativeId "GO:0016478" ; oboInOwl:hasExactSynonym "down regulation of protein biosynthetic process", "down-regulation of protein biosynthetic process", "downregulation of protein biosynthetic process", "negative regulation of protein anabolism", "negative regulation of protein biosynthesis", "negative regulation of protein biosynthetic process", "negative regulation of protein formation", "negative regulation of protein synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of protein biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein biosynthesis inhibitor activity", "protein biosynthetic process inhibitor activity" ; oboInOwl:id "GO:0017148" ; a owl:Class ; rdfs:label "negative regulation of translation" ; rdfs:subClassOf obo:GO_0006417, obo:GO_0010558, obo:GO_0010629, obo:GO_0031327, obo:GO_0034249, obo:GO_0051248, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0017157 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of exocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0017157" ; a owl:Class ; rdfs:label "regulation of exocytosis" ; rdfs:subClassOf obo:GO_0060627, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006887 ] ) ] . obo:GO_0018130 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." ; oboInOwl:hasExactSynonym "heterocycle anabolism", "heterocycle biosynthesis", "heterocycle formation", "heterocycle synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018130" ; a owl:Class ; rdfs:label "heterocycle biosynthetic process" ; rdfs:subClassOf obo:GO_0044249, obo:GO_0046483, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_5686 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_5686 ] ) ] . obo:GO_0018958 obo:IAO_0000115 "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ; oboInOwl:hasDbXref "UM-BBD_pathwayID:phe" ; oboInOwl:hasExactSynonym "carbolic acid metabolic process", "carbolic acid metabolism", "hydroxybenzene metabolic process", "hydroxybenzene metabolism", "phenol-containing compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018958" ; a owl:Class ; rdfs:comment "Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds." ; rdfs:label "phenol-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_1901360, obo:GO_1901615, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33853 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33853 ] ) ] . obo:GO_0018985 obo:IAO_0000115 "Synthesis and ordering of the envelope of pronuclei." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018985" ; a owl:Class ; rdfs:label "pronuclear envelope synthesis" ; rdfs:subClassOf obo:GO_0006998, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007338 ] . obo:GO_0018991 obo:IAO_0000115 "A reproductive behavior that results in the deposition of eggs (either fertilized or not) upon a surface or into a medium such as water." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24955"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0060403" ; oboInOwl:hasBroadSynonym "egg laying", "egg-laying" ; oboInOwl:hasDbXref "Wikipedia:Oviposition" ; oboInOwl:hasExactSynonym "oviposition" ; oboInOwl:hasNarrowSynonym "post-mating oviposition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018991" ; a owl:Class ; rdfs:label "egg-laying behavior" ; rdfs:subClassOf obo:GO_0019098 . obo:GO_0018992 obo:IAO_0000115 "The determination of sex and sexual phenotype in an organism's germ line." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018992" ; a owl:Class ; rdfs:label "germ-line sex determination" ; rdfs:subClassOf obo:GO_0007530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0018996 obo:IAO_0000115 "The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans." ; oboInOwl:hasExactSynonym "collagen and cuticulin-based cuticle molting cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018996" ; a owl:Class ; rdfs:label "molting cycle, collagen and cuticulin-based cuticle" ; rdfs:subClassOf obo:GO_0042303 . obo:GO_0019093 obo:IAO_0000115 "Any process in which mitochondrial RNA is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "establishment and maintenance of mitochondrial RNA localization", "mitochondrial RNA localisation", "mtRNA localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019093" ; a owl:Class ; rdfs:label "mitochondrial RNA localization" ; rdfs:subClassOf obo:GO_0006403, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006403 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0019098 obo:IAO_0000115 "The specific behavior of an organism that is associated with reproduction." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23491"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T16:01:37Z" ; oboInOwl:hasAlternativeId "GO:0033057", "GO:0044704", "GO:0044705" ; oboInOwl:hasExactSynonym "reproductive behavior in a multicellular organism", "reproductive behaviour" ; oboInOwl:hasNarrowSynonym "multi-organism reproductive behavior", "multicellular organism reproductive behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism reproductive behavior" ; oboInOwl:id "GO:0019098" ; a owl:Class ; rdfs:label "reproductive behavior" ; rdfs:subClassOf obo:GO_0007610, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007610 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] ) ] . obo:GO_0019216 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." ; oboInOwl:hasExactSynonym "regulation of lipid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019216" ; a owl:Class ; rdfs:label "regulation of lipid metabolic process" ; rdfs:subClassOf obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006629 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006629 ] ) ] . obo:GO_0019218 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids." ; oboInOwl:hasExactSynonym "regulation of steroid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019218" ; a owl:Class ; rdfs:label "regulation of steroid metabolic process" ; rdfs:subClassOf obo:GO_0019216, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008202 ] ) ] . obo:GO_0019219 obo:IAO_0000115 "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:id "GO:0019219" ; a owl:Class ; rdfs:label "regulation of nucleobase-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0031323, obo:GO_0051171, obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006139 ] ) ] . obo:GO_0019220 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ; oboInOwl:hasExactSynonym "regulation of phosphate metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019220" ; a owl:Class ; rdfs:label "regulation of phosphate metabolic process" ; rdfs:subClassOf obo:GO_0051174, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006796 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006796 ] ) ] . obo:GO_0019222 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ; oboInOwl:hasAlternativeId "GO:0044246" ; oboInOwl:hasExactSynonym "regulation of metabolism" ; oboInOwl:hasNarrowSynonym "regulation of multicellular organismal metabolic process", "regulation of organismal metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019222" ; oboInOwl:inSubset go:goslim_metagenomics ; a owl:Class ; rdfs:label "regulation of metabolic process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008152 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008152 ] ) ] . obo:GO_0019226 obo:IAO_0000115 "The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission." ; oboInOwl:hasExactSynonym "conduction of nerve impulse", "signal transmission along a neuron" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019226" ; a owl:Class ; rdfs:label "transmission of nerve impulse" ; rdfs:subClassOf obo:GO_0050877, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007154 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0001508 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0007268 ] . obo:GO_0019228 obo:IAO_0000115 "An action potential that occurs in a neuron." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "generation of action potential" ; oboInOwl:id "GO:0019228" ; a owl:Class ; rdfs:label "neuronal action potential" ; rdfs:subClassOf obo:GO_0001508, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019226 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000540 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001508 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0019233 obo:IAO_0000115 "The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process." ; oboInOwl:hasDbXref "Wikipedia:Nociception" ; oboInOwl:hasNarrowSynonym "perception of physiological pain" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nociception" ; oboInOwl:id "GO:0019233" ; a owl:Class ; rdfs:label "sensory perception of pain" ; rdfs:subClassOf obo:GO_0007600 . obo:GO_0019318 obo:IAO_0000115 "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule." ; oboInOwl:hasExactSynonym "hexose metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019318" ; a owl:Class ; rdfs:label "hexose metabolic process" ; rdfs:subClassOf obo:GO_0005996, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18133 ] ) ] . obo:GO_0019319 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." ; oboInOwl:hasExactSynonym "hexose anabolism", "hexose biosynthesis", "hexose formation", "hexose synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019319" ; a owl:Class ; rdfs:label "hexose biosynthetic process" ; rdfs:subClassOf obo:GO_0019318, obo:GO_0046364, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18133 ] ) ] . obo:GO_0019320 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule." ; oboInOwl:hasExactSynonym "hexose breakdown", "hexose catabolism", "hexose degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019320" ; a owl:Class ; rdfs:label "hexose catabolic process" ; rdfs:subClassOf obo:GO_0019318, obo:GO_0046365, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18133 ] ) ] . obo:GO_0019336 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ; oboInOwl:hasDbXref "MetaCyc:PHENOLDEG-PWY" ; oboInOwl:hasExactSynonym "phenol-containing compound breakdown", "phenol-containing compound catabolism", "phenol-containing compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019336" ; a owl:Class ; rdfs:label "phenol-containing compound catabolic process" ; rdfs:subClassOf obo:GO_0018958, obo:GO_0019439, obo:GO_1901361, obo:GO_1901616, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33853 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33853 ] ) ] . obo:GO_0019413 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid." ; oboInOwl:hasExactSynonym "acetate anabolism", "acetate biosynthesis", "acetate formation", "acetate synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019413" ; a owl:Class ; rdfs:label "acetate biosynthetic process" ; rdfs:subClassOf obo:GO_0006083, obo:GO_0072330, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_30089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_30089 ] ) ] . obo:GO_0019438 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." ; oboInOwl:hasExactSynonym "aromatic compound anabolism", "aromatic compound biosynthesis", "aromatic compound formation", "aromatic compound synthesis" ; oboInOwl:hasNarrowSynonym "aromatic hydrocarbon biosynthesis", "aromatic hydrocarbon biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019438" ; a owl:Class ; rdfs:label "aromatic compound biosynthetic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_0044249, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33655 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33655 ] ) ] . obo:GO_0019439 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring." ; oboInOwl:hasExactSynonym "aromatic compound breakdown", "aromatic compound catabolism", "aromatic compound degradation" ; oboInOwl:hasNarrowSynonym "aromatic hydrocarbon catabolic process", "aromatic hydrocarbon catabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019439" ; a owl:Class ; rdfs:label "aromatic compound catabolic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_0044248, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33655 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33655 ] ) ] . obo:GO_0019538 obo:IAO_0000115 "The chemical reactions and pathways involving a protein. Includes protein modification." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006411", "GO:0044267", "GO:0044268" ; oboInOwl:hasDbXref "Wikipedia:Protein_metabolism" ; oboInOwl:hasExactSynonym "cellular protein metabolic process", "cellular protein metabolism", "protein metabolic process and modification", "protein metabolism", "protein metabolism and modification" ; oboInOwl:hasNarrowSynonym "multicellular organismal protein metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019538" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "protein metabolic process" ; rdfs:subClassOf obo:GO_0043170, obo:GO_0044238, obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:PR_000000001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0019614 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "catechol breakdown", "catechol catabolic process", "catechol catabolism", "catechol degradation" ; oboInOwl:id "GO:0019614" ; a owl:Class ; rdfs:label "catechol-containing compound catabolic process" ; rdfs:subClassOf obo:GO_0009712, obo:GO_0019336, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33566 ] ) ] . obo:GO_0019722 obo:IAO_0000115 "Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions." ; oboInOwl:hasDbXref "Wikipedia:Calcium_signaling" ; oboInOwl:hasExactSynonym "calcium ion signaling", "calcium signaling", "calcium signalling", "calcium-mediated signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019722" ; a owl:Class ; rdfs:label "calcium-mediated signaling" ; rdfs:subClassOf obo:GO_0019932 . obo:GO_0019725 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state at the level of the cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019725" ; oboInOwl:inSubset go:goslim_candida, go:goslim_plant ; a owl:Class ; rdfs:label "cellular homeostasis" ; rdfs:subClassOf obo:GO_0042592, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000000 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_131567 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_131567 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith obo:GO_0048872 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042592 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000000 ] ) ] . obo:GO_0019748 obo:IAO_0000115 "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." ; oboInOwl:hasDbXref "Wikipedia:Secondary_metabolism" ; oboInOwl:hasExactSynonym "secondary metabolism", "secondary metabolite metabolic process", "secondary metabolite metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019748" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir, go:goslim_plant, go:goslim_pombe ; a owl:Class ; rdfs:label "secondary metabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0019752 obo:IAO_0000115 "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." ; oboInOwl:hasExactSynonym "carboxylic acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019752" ; a owl:Class ; rdfs:label "carboxylic acid metabolic process" ; rdfs:subClassOf obo:GO_0043436, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_29067 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_29067 ] ) ] . obo:GO_0019755 obo:IAO_0000115 "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "one carbon compound transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019755" ; a owl:Class ; rdfs:label "one-carbon compound transport" ; rdfs:subClassOf obo:GO_0071702, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64708 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64708 ] ) ] . obo:GO_0019825 obo:IAO_0000115 "Binding to oxygen (O2)." ; oboInOwl:hasNarrowSynonym "cytochrome P450" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "cytochrome P450 activity" ; oboInOwl:id "GO:0019825" ; oboInOwl:inSubset go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "oxygen binding" ; rdfs:subClassOf obo:GO_0036094, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_15379 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_15379 ] ) ] . obo:GO_0019827 obo:IAO_0000115 "The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "maintenance of pluripotency" ; oboInOwl:id "GO:0019827" ; a owl:Class ; rdfs:label "stem cell population maintenance" ; rdfs:subClassOf obo:GO_0032501, obo:GO_0098727, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000034 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098727 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000034 ] ) ] . obo:GO_0019867 obo:IAO_0000115 "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0019867" ; oboInOwl:inSubset go:goslim_metagenomics ; a owl:Class ; rdfs:label "outer membrane" ; rdfs:subClassOf obo:GO_0016020 . obo:GO_0019882 obo:IAO_0000115 "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex." ; oboInOwl:hasAlternativeId "GO:0030333" ; oboInOwl:hasDbXref "Wikipedia:Antigen_presentation" ; oboInOwl:hasExactSynonym "antigen presentation", "antigen processing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019882" ; a owl:Class ; rdfs:label "antigen processing and presentation" ; rdfs:subClassOf obo:GO_0002376 . obo:GO_0019932 obo:IAO_0000115 "Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell." ; oboInOwl:hasExactSynonym "second messenger mediated signaling", "second messenger mediated signalling", "second messenger-mediated signaling", "second messenger-mediated signalling", "second-messenger-mediated signal transduction", "second-messenger-mediated signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019932" ; a owl:Class ; rdfs:label "second-messenger-mediated signaling" ; rdfs:subClassOf obo:GO_0035556 . obo:GO_0019953 obo:IAO_0000115 "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22929"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Sexual_reproduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019953" ; a owl:Class ; rdfs:comment "Note that gametes may come from two organisms or from a single organism in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. Note also that sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times." ; rdfs:label "sexual reproduction" ; rdfs:subClassOf obo:GO_0000003 . obo:GO_0021501 obo:IAO_0000115 "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021501" ; a owl:Class ; rdfs:label "prechordal plate formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003063 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003063 ] ) ] . obo:GO_0021510 obo:IAO_0000115 "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021510" ; a owl:Class ; rdfs:label "spinal cord development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007417 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002240 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002240 ] ) ] . obo:GO_0021514 obo:IAO_0000115 "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021514" ; a owl:Class ; rdfs:label "ventral spinal cord interneuron differentiation" ; rdfs:subClassOf obo:GO_0021515, obo:GO_0021953, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021517 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000099 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002240 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000099 ] ) ] . obo:GO_0021515 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021515" ; a owl:Class ; rdfs:label "cell differentiation in spinal cord" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021510 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002240 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002240 ] ) ] . obo:GO_0021517 obo:IAO_0000115 "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021517" ; a owl:Class ; rdfs:label "ventral spinal cord development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021510 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002257 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002257 ] ) ] . obo:GO_0021522 obo:IAO_0000115 "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021522" ; a owl:Class ; rdfs:label "spinal cord motor neuron differentiation" ; rdfs:subClassOf obo:GO_0021515, obo:GO_0021953, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021517 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0011001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0011001 ] ) ] . obo:GO_0021523 obo:IAO_0000115 "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021523" ; a owl:Class ; rdfs:label "somatic motor neuron differentiation" ; rdfs:subClassOf obo:GO_0021522, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0005024 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0005024 ] ) ] . obo:GO_0021532 obo:IAO_0000115 "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021532" ; a owl:Class ; rdfs:label "neural tube patterning" ; rdfs:subClassOf obo:GO_0003002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021915 ] . obo:GO_0021533 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021533" ; a owl:Class ; rdfs:label "cell differentiation in hindbrain" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030902 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002028 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_89593 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_89593 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002028 ] ) ] . obo:GO_0021534 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021534" ; a owl:Class ; rdfs:label "cell proliferation in hindbrain" ; rdfs:subClassOf obo:GO_0061351, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030902 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002028 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_89593 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_89593 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002028 ] ) ] . obo:GO_0021535 obo:IAO_0000115 "The orderly movement of a cell that will reside in the hindbrain." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021535" ; a owl:Class ; rdfs:label "cell migration in hindbrain" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030902 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002028 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_89593 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_89593 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002028 ] ) ] . obo:GO_0021545 obo:IAO_0000115 "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021545" ; a owl:Class ; rdfs:label "cranial nerve development" ; rdfs:subClassOf obo:GO_0021675, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001785 ] ) ] . obo:GO_0021546 obo:IAO_0000115 "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021546" ; a owl:Class ; rdfs:label "rhombomere development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001892 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001892 ] ) ] . obo:GO_0021547 obo:IAO_0000115 "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." ; oboInOwl:hasExactSynonym "MHB biosynthesis", "MHB formation", "midbrain-hindbrain boundary biosynthesis", "midbrain-hindbrain boundary formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "isthmus biosynthesis", "isthmus formation" ; oboInOwl:id "GO:0021547" ; a owl:Class ; rdfs:label "midbrain-hindbrain boundary initiation" ; rdfs:subClassOf obo:GO_0003002, obo:GO_0048859, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021999 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030917 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003052 ] ) ] . obo:GO_0021548 obo:IAO_0000115 "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021548" ; a owl:Class ; rdfs:label "pons development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0022037 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000988 ] ) ] . obo:GO_0021550 obo:IAO_0000115 "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "medulla development", "myelencephalon development" ; oboInOwl:id "GO:0021550" ; a owl:Class ; rdfs:label "medulla oblongata development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001896 ] ) ] . obo:GO_0021551 obo:IAO_0000115 "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021551" ; a owl:Class ; rdfs:label "central nervous system morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007417 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001017 ] ) ] . obo:GO_0021555 obo:IAO_0000115 "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." ; oboInOwl:hasExactSynonym "MHB morphogenesis", "isthmus morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021555" ; a owl:Class ; rdfs:label "midbrain-hindbrain boundary morphogenesis" ; rdfs:subClassOf obo:GO_0048598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030917 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003052 ] ) ] . obo:GO_0021556 obo:IAO_0000115 "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021556" ; a owl:Class ; rdfs:label "central nervous system formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021551 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001017 ] ) ] . obo:GO_0021559 obo:IAO_0000115 "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." ; oboInOwl:hasExactSynonym "cranial nerve 5 development", "cranial nerve V development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "CN V development" ; oboInOwl:id "GO:0021559" ; a owl:Class ; rdfs:label "trigeminal nerve development" ; rdfs:subClassOf obo:GO_0021545, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001645 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001645 ] ) ] . obo:GO_0021575 obo:IAO_0000115 "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "rhombencephalon morphogenesis" ; oboInOwl:id "GO:0021575" ; a owl:Class ; rdfs:label "hindbrain morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002028 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002028 ] ) ] . obo:GO_0021576 obo:IAO_0000115 "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021576" ; a owl:Class ; rdfs:label "hindbrain formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021575 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002028 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002028 ] ) ] . obo:GO_0021578 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021578" ; a owl:Class ; rdfs:label "hindbrain maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021626 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0002028 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0002028 ] ) ] . obo:GO_0021579 obo:IAO_0000115 "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "medulla morphogenesis", "myelencephalon morphogenesis" ; oboInOwl:id "GO:0021579" ; a owl:Class ; rdfs:label "medulla oblongata morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021550 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021575 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001896 ] ) ] . obo:GO_0021580 obo:IAO_0000115 "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "medulla biosynthesis", "medulla formation", "myelencephalon biosynthesis", "myelencephalon formation" ; oboInOwl:id "GO:0021580" ; a owl:Class ; rdfs:label "medulla oblongata formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021576 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021579 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001896 ] ) ] . obo:GO_0021582 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "medulla maturation", "myelencephalon maturation" ; oboInOwl:id "GO:0021582" ; a owl:Class ; rdfs:label "medulla oblongata maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021550 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021578 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001896 ] ) ] . obo:GO_0021583 obo:IAO_0000115 "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021583" ; a owl:Class ; rdfs:label "pons morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021548 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021575 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000988 ] ) ] . obo:GO_0021584 obo:IAO_0000115 "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021584" ; a owl:Class ; rdfs:label "pons formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021576 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021583 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000988 ] ) ] . obo:GO_0021586 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021586" ; a owl:Class ; rdfs:label "pons maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021548 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021578 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000988 ] ) ] . obo:GO_0021593 obo:IAO_0000115 "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021593" ; a owl:Class ; rdfs:label "rhombomere morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021546 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001892 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001892 ] ) ] . obo:GO_0021594 obo:IAO_0000115 "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021594" ; a owl:Class ; rdfs:label "rhombomere formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021593 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001892 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001892 ] ) ] . obo:GO_0021602 obo:IAO_0000115 "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021602" ; a owl:Class ; rdfs:label "cranial nerve morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021545 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001785 ] ) ] . obo:GO_0021603 obo:IAO_0000115 "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021603" ; a owl:Class ; rdfs:label "cranial nerve formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021602 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001785 ] ) ] . obo:GO_0021605 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021605" ; a owl:Class ; rdfs:label "cranial nerve maturation" ; rdfs:subClassOf obo:GO_0021682, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021545 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001785 ] ) ] . obo:GO_0021626 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021626" ; a owl:Class ; rdfs:label "central nervous system maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007417 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001017 ] ) ] . obo:GO_0021635 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "CN V maturation" ; oboInOwl:id "GO:0021635" ; a owl:Class ; rdfs:label "trigeminal nerve maturation" ; rdfs:subClassOf obo:GO_0021605, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021559 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001645 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001645 ] ) ] . obo:GO_0021636 obo:IAO_0000115 "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "CN V morphogenesis" ; oboInOwl:id "GO:0021636" ; a owl:Class ; rdfs:label "trigeminal nerve morphogenesis" ; rdfs:subClassOf obo:GO_0021602, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021559 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001645 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001645 ] ) ] . obo:GO_0021638 obo:IAO_0000115 "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "CN V biosynthesis", "CN V formation" ; oboInOwl:id "GO:0021638" ; a owl:Class ; rdfs:label "trigeminal nerve formation" ; rdfs:subClassOf obo:GO_0021603, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021636 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001645 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001645 ] ) ] . obo:GO_0021654 obo:IAO_0000115 "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021654" ; a owl:Class ; rdfs:label "rhombomere boundary formation" ; rdfs:subClassOf obo:GO_0048859, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021594 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0018239 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0018239 ] ) ] . obo:GO_0021675 obo:IAO_0000115 "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021675" ; a owl:Class ; rdfs:label "nerve development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001021 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001021 ] ) ] . obo:GO_0021682 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021682" ; a owl:Class ; rdfs:label "nerve maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021675 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001021 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001021 ] ) ] . obo:GO_0021700 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021700" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "developmental maturation" ; rdfs:subClassOf obo:GO_0032502 . obo:GO_0021703 obo:IAO_0000115 "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." ; oboInOwl:hasExactSynonym "locus caeruleus development", "locus coeruleus development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021703" ; a owl:Class ; rdfs:label "locus ceruleus development" ; rdfs:subClassOf obo:GO_0048857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021548 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002148 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002148 ] ) ] . obo:GO_0021704 obo:IAO_0000115 "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021704" ; a owl:Class ; rdfs:label "locus ceruleus morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021583 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002148 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002148 ] ) ] . obo:GO_0021705 obo:IAO_0000115 "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021705" ; a owl:Class ; rdfs:label "locus ceruleus formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021584 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021704 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002148 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002148 ] ) ] . obo:GO_0021706 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021706" ; a owl:Class ; rdfs:label "locus ceruleus maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021586 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0002148 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0002148 ] ) ] . obo:GO_0021718 obo:IAO_0000115 "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "superior olive development" ; oboInOwl:id "GO:0021718" ; a owl:Class ; rdfs:label "superior olivary nucleus development" ; rdfs:subClassOf obo:GO_0048857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021548 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0007247 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0007247 ] ) ] . obo:GO_0021719 obo:IAO_0000115 "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "superior olive morphogenesis" ; oboInOwl:id "GO:0021719" ; a owl:Class ; rdfs:label "superior olivary nucleus morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021583 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021718 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007247 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007247 ] ) ] . obo:GO_0021720 obo:IAO_0000115 "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021720" ; a owl:Class ; rdfs:label "superior olivary nucleus formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021584 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021719 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0007247 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0007247 ] ) ] . obo:GO_0021722 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "superior olive maturation" ; oboInOwl:id "GO:0021722" ; a owl:Class ; rdfs:label "superior olivary nucleus maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021586 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021718 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0007247 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0007247 ] ) ] . obo:GO_0021732 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "MHB maturation", "isthmus maturation" ; oboInOwl:id "GO:0021732" ; a owl:Class ; rdfs:label "midbrain-hindbrain boundary maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030917 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0003052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0003052 ] ) ] . obo:GO_0021751 obo:IAO_0000115 "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021751" ; a owl:Class ; rdfs:label "salivary nucleus development" ; rdfs:subClassOf obo:GO_0048857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021548 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004133 ] ) ] . obo:GO_0021753 obo:IAO_0000115 "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021753" ; a owl:Class ; rdfs:label "superior salivary nucleus development" ; rdfs:subClassOf obo:GO_0021751, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002149 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002149 ] ) ] . obo:GO_0021782 obo:IAO_0000115 "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021782" ; a owl:Class ; rdfs:label "glial cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000125 ] ) ] . obo:GO_0021903 obo:IAO_0000115 "The process in which the neural tube is divided into specific regions along the rostrocaudal axis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "anterior-posterior neural tube patterning" ; oboInOwl:id "GO:0021903" ; a owl:Class ; rdfs:label "rostrocaudal neural tube patterning" ; rdfs:subClassOf obo:GO_0009952, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021532 ] . obo:GO_0021906 obo:IAO_0000115 "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021906" ; a owl:Class ; rdfs:label "hindbrain-spinal cord boundary formation" ; rdfs:subClassOf obo:GO_0048859, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021903 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005076 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005076 ] ) ] . obo:GO_0021915 obo:IAO_0000115 "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021915" ; a owl:Class ; rdfs:label "neural tube development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043009 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001049 ] ) ] . obo:GO_0021953 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021953" ; a owl:Class ; rdfs:label "central nervous system neuron differentiation" ; rdfs:subClassOf obo:GO_0030182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007417 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000029 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000029 ] ) ] . obo:GO_0021954 obo:IAO_0000115 "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021954" ; a owl:Class ; rdfs:label "central nervous system neuron development" ; rdfs:subClassOf obo:GO_0048666, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021953 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_2000029 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_2000029 ] ) ] . obo:GO_0021990 obo:IAO_0000115 "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021990" ; a owl:Class ; rdfs:label "neural plate formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001839 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003075 ] ) ] . obo:GO_0021999 obo:IAO_0000115 "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neural plate anterior/posterior pattern formation" ; oboInOwl:id "GO:0021999" ; a owl:Class ; rdfs:label "neural plate anterior/posterior regionalization" ; rdfs:subClassOf obo:GO_0009952, obo:GO_0060897 . obo:GO_0022008 obo:IAO_0000115 "Generation of cells within the nervous system." ; oboInOwl:hasDbXref "Wikipedia:Neurogenesis" ; oboInOwl:hasExactSynonym "nervous system cell generation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neural cell differentiation" ; oboInOwl:id "GO:0022008" ; a owl:Class ; rdfs:label "neurogenesis" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ] . obo:GO_0022009 obo:IAO_0000115 "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21480"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022009" ; a owl:Class ; rdfs:label "central nervous system vasculogenesis" ; rdfs:subClassOf obo:GO_0001570, [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001570 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001017 ] ) ] . obo:GO_0022035 obo:IAO_0000115 "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022035" ; a owl:Class ; rdfs:label "rhombomere cell migration" ; rdfs:subClassOf obo:GO_0021535, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021546 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:UBERON_0001892 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:UBERON_0001892 ] ) ] . obo:GO_0022037 obo:IAO_0000115 "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022037" ; a owl:Class ; rdfs:label "metencephalon development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001895 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001895 ] ) ] . obo:GO_0022402 obo:IAO_0000115 "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022402" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "cell cycle process" ; rdfs:subClassOf obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0022403 obo:IAO_0000115 "One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022403" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "cell cycle phase" ; rdfs:subClassOf obo:GO_0044848 . obo:GO_0022404 obo:IAO_0000115 "A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022404" ; a owl:Class ; rdfs:label "molting cycle process" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042303 ] . obo:GO_0022406 obo:IAO_0000115 "The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022406" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "membrane docking" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0022407 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022407" ; a owl:Class ; rdfs:label "regulation of cell-cell adhesion" ; rdfs:subClassOf obo:GO_0030155, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0098609 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0022408 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." ; oboInOwl:hasExactSynonym "down regulation of cell-cell adhesion", "down-regulation of cell-cell adhesion", "downregulation of cell-cell adhesion" ; oboInOwl:hasNarrowSynonym "inhibition of cell-cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022408" ; a owl:Class ; rdfs:label "negative regulation of cell-cell adhesion" ; rdfs:subClassOf obo:GO_0007162, obo:GO_0022407, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0098609 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0022409 obo:IAO_0000115 "Any process that activates or increases the rate or extent of cell adhesion to another cell." ; oboInOwl:hasExactSynonym "up regulation of cell-cell adhesion", "up-regulation of cell-cell adhesion", "upregulation of cell-cell adhesion" ; oboInOwl:hasNarrowSynonym "activation of cell-cell adhesion", "stimulation of cell-cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022409" ; a owl:Class ; rdfs:label "positive regulation of cell-cell adhesion" ; rdfs:subClassOf obo:GO_0022407, obo:GO_0045785, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0098609 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0022411 obo:IAO_0000115 "A cellular process that results in the breakdown of a cellular component." ; oboInOwl:hasAlternativeId "GO:0071845" ; oboInOwl:hasExactSynonym "cell structure disassembly", "cellular component disassembly at cellular level" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022411" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular component disassembly" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005575 ] ; owl:disjointWith obo:GO_0022607 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005575 ] ) ] . obo:GO_0022412 obo:IAO_0000115 "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." ; oboInOwl:hasExactSynonym "reproductive cellular process in multicellular organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022412" ; a owl:Class ; rdfs:label "cellular process involved in reproduction in multicellular organism" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] ) ] . obo:GO_0022414 obo:IAO_0000115 "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T15:56:06Z" ; oboInOwl:hasAlternativeId "GO:0044702" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism reproductive process" ; oboInOwl:id "GO:0022414" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "reproductive process" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000003 ] ; owl:disjointWith obo:GO_0044848 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000003 ] ) ] . obo:GO_0022600 obo:IAO_0000115 "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022600" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "digestive system process" ; rdfs:subClassOf obo:GO_0003008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007586 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0003008 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007586 ] ) ] . obo:GO_0022602 obo:IAO_0000115 "A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "estrous cycle process", "menstrual cycle process" ; oboInOwl:id "GO:0022602" ; a owl:Class ; rdfs:label "ovulation cycle process" ; rdfs:subClassOf obo:GO_0022414, obo:GO_0048511, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042698 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042698 ] ) ] . obo:GO_0022603 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." ; oboInOwl:hasExactSynonym "regulation of morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022603" ; a owl:Class ; rdfs:label "regulation of anatomical structure morphogenesis" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009653 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009653 ] ) ] . obo:GO_0022604 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell shape and cell size", "positive regulation of cell shape and cell size", "regulation of cell shape and cell size" ; oboInOwl:id "GO:0022604" ; a owl:Class ; rdfs:label "regulation of cell morphogenesis" ; rdfs:subClassOf obo:GO_0022603, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000902 ] ) ] . obo:GO_0022607 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a cellular component." ; oboInOwl:hasAlternativeId "GO:0071844" ; oboInOwl:hasExactSynonym "cell structure assembly", "cellular component assembly at cellular level" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022607" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "cellular component assembly" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044085 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005575 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005575 ] ) ] . obo:GO_0022611 obo:IAO_0000115 "A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated." ; oboInOwl:hasNarrowSynonym "multicellular organism dormancy process", "spore dormancy process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022611" ; a owl:Class ; rdfs:comment "In plants and animals, dormancy may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. In plants, dormancy may involve the formation of dormant buds, and may be preceded by the senescence of plant parts such as leaves in woody plants or most of the shoot system in herbaceous perennials. The exit from dormancy in vascular plants is marked by resumed growth of buds and/or growth of vascular cambium." ; rdfs:label "dormancy process" ; rdfs:subClassOf obo:GO_0032502 . obo:GO_0022612 obo:IAO_0000115 "The process in which the anatomical structures of a gland are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022612" ; a owl:Class ; rdfs:label "gland morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048732 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002530 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002530 ] ) ] . obo:GO_0022613 obo:IAO_0000115 "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." ; oboInOwl:hasExactSynonym "RNA-protein complex biogenesis", "ribonucleoprotein complex biogenesis and assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022613" ; a owl:Class ; rdfs:label "ribonucleoprotein complex biogenesis" ; rdfs:subClassOf obo:GO_0044085 . obo:GO_0022617 obo:IAO_0000115 "A process that results in the breakdown of the extracellular matrix." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022617" ; a owl:Class ; rdfs:label "extracellular matrix disassembly" ; rdfs:subClassOf obo:GO_0022411, obo:GO_0030198, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0031012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0031012 ] ) ] . obo:GO_0022618 obo:IAO_0000115 "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." ; oboInOwl:hasExactSynonym "RNA-protein complex assembly", "RNP complex assembly", "ribonucleoprotein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022618" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "protein-RNA complex assembly" ; rdfs:subClassOf obo:GO_0065003, obo:GO_0071826, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0022613 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_1990904 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_1990904 ] ) ] . obo:GO_0022804 obo:IAO_0000115 "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction." ; oboInOwl:hasExactSynonym "active carrier activity", "carrier activity", "permease activity", "pump activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0022804" ; a owl:Class ; rdfs:label "active transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857 . obo:GO_0022853 obo:IAO_0000115 "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24479"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "active ion transmembrane transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0022853" ; a owl:Class ; rdfs:label "active monoatomic ion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015075, obo:GO_0022804 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022804 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24867 ] ) ] . obo:GO_0022857 obo:IAO_0000115 "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other." ; oboInOwl:hasAlternativeId "GO:0005386", "GO:0015563", "GO:0015646", "GO:0022891", "GO:0022892" ; oboInOwl:hasDbXref "Reactome:R-HSA-1236947", "Reactome:R-HSA-429036", "Reactome:R-HSA-5638209", "Reactome:R-HSA-5671707", "Reactome:R-HSA-6784434", "Reactome:R-HSA-6784436" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "substrate-specific transmembrane transporter activity", "substrate-specific transporter activity", "uptake permease activity", "uptake transmembrane transporter activity" ; oboInOwl:id "GO:0022857" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_yeast ; a owl:Class ; rdfs:label "transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0005215, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055085 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005215 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0022884 obo:IAO_0000115 "Enables the transfer of a macromolecule from one side of a membrane to the other." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0022884" ; a owl:Class ; rdfs:label "macromolecule transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33694 ] ) ] . obo:GO_0022890 obo:IAO_0000115 "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage." ; oboInOwl:hasAlternativeId "GO:0015077", "GO:0015082", "GO:0072509", "GO:0072510" ; oboInOwl:hasNarrowSynonym "di-, tri-valent inorganic cation transmembrane transporter activity", "divalent inorganic cation transmembrane transporter activity", "monovalent inorganic cation transmembrane transporter activity", "trivalent inorganic cation transmembrane transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0022890" ; a owl:Class ; rdfs:label "inorganic cation transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015318, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36915 ] ) ] . obo:GO_0022898 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of transmembrane transporter activity." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022898" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0032409, obo:GO_0034762, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022857 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022857 ] ) ] . obo:GO_0023019 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of gene expression as a consequence of signal transmission" ; oboInOwl:id "GO:0023019" ; a owl:Class ; rdfs:label "signal transduction involved in regulation of gene expression" ; rdfs:subClassOf obo:GO_0007165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007165 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010468 ] ) ] . obo:GO_0023023 obo:IAO_0000115 "Binding to a major histocompatibility complex." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0023023" ; a owl:Class ; rdfs:label "MHC protein complex binding" ; rdfs:subClassOf obo:GO_0044877, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0042611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0042611 ] ) ] . obo:GO_0023026 obo:IAO_0000115 "Binding to a class II major histocompatibility complex." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0023026" ; a owl:Class ; rdfs:label "MHC class II protein complex binding" ; rdfs:subClassOf obo:GO_0023023, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0042613 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0042613 ] ) ] . obo:GO_0023051 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a signaling process." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of signaling process", "regulation of signalling process" ; oboInOwl:id "GO:0023051" ; a owl:Class ; rdfs:label "regulation of signaling" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0023052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0023052 ] ) ] . obo:GO_0023052 obo:IAO_0000115 "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasAlternativeId "GO:0023046", "GO:0044700" ; oboInOwl:hasExactSynonym "biological signaling", "signaling process", "signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "signalling process", "single organism signaling" ; oboInOwl:id "GO:0023052" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ; rdfs:label "signaling" ; rdfs:subClassOf obo:GO_0050789 ; owl:disjointWith obo:GO_0044848 . obo:GO_0023056 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasExactSynonym "positive regulation of signalling process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of signaling process" ; oboInOwl:id "GO:0023056" ; a owl:Class ; rdfs:label "positive regulation of signaling" ; rdfs:subClassOf obo:GO_0023051, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0023052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0023052 ] ) ] . obo:GO_0023057 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of signaling process", "negative regulation of signalling process" ; oboInOwl:id "GO:0023057" ; a owl:Class ; rdfs:label "negative regulation of signaling" ; rdfs:subClassOf obo:GO_0023051, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0023052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0023052 ] ) ] . obo:GO_0023061 obo:IAO_0000115 "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasExactSynonym "signal secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0023061" ; a owl:Class ; rdfs:label "signal release" ; rdfs:subClassOf obo:GO_0032940, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007267 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032940 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007267 ] ) ] . obo:GO_0030001 obo:IAO_0000115 "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23033"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-07-31T01:07:46Z" ; oboInOwl:hasAlternativeId "GO:0070838", "GO:0070839" ; oboInOwl:hasNarrowSynonym "divalent metal ion export", "divalent metal ion transport", "heavy metal ion transport", "metal ion export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030001" ; a owl:Class ; rdfs:label "metal ion transport" ; rdfs:subClassOf obo:GO_0006812, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25213 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25213 ] ) ] . obo:GO_0030003 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "cellular cation homeostasis" ; oboInOwl:hasExactSynonym "cellular monoatomic cation homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030003" ; a owl:Class ; rdfs:label "intracellular monoatomic cation homeostasis" ; rdfs:subClassOf obo:GO_0006873, obo:GO_0055080 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019725 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_23906 ] ) ] . obo:GO_0030010 obo:IAO_0000115 "The specification and formation of anisotropic intracellular organization or cell growth patterns." ; oboInOwl:hasAlternativeId "GO:0000283", "GO:0030468" ; oboInOwl:hasExactSynonym "cell polarization" ; oboInOwl:hasNarrowSynonym "bud site selection/establishment of cell polarity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030010" ; a owl:Class ; rdfs:label "establishment of cell polarity" ; rdfs:subClassOf obo:GO_0007163 . obo:GO_0030016 obo:IAO_0000115 "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." ; oboInOwl:hasDbXref "Wikipedia:Myofibril" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030016" ; a owl:Class ; rdfs:label "myofibril" ; rdfs:subClassOf obo:GO_0043292, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043292 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000737 ] ) ] . obo:GO_0030017 obo:IAO_0000115 "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ; oboInOwl:hasDbXref "Wikipedia:Sarcomere" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030017" ; a owl:Class ; rdfs:label "sarcomere" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030016 ] . obo:GO_0030029 obo:IAO_0000115 "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microfilament-based process" ; oboInOwl:id "GO:0030029" ; a owl:Class ; rdfs:label "actin filament-based process" ; rdfs:subClassOf obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0005884 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0005884 ] ) ] . obo:GO_0030030 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." ; oboInOwl:hasExactSynonym "cell projection organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell projection organization and biogenesis", "cell surface structure organization and biogenesis" ; oboInOwl:id "GO:0030030" ; oboInOwl:inSubset go:prokaryote_subset ; a owl:Class ; rdfs:label "cell projection organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0042995 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0042995 ] ) ] . obo:GO_0030031 obo:IAO_0000115 "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon." ; oboInOwl:hasExactSynonym "formation of a cell surface projection" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell projection biogenesis" ; oboInOwl:id "GO:0030031" ; a owl:Class ; rdfs:label "cell projection assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0030030, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0042995 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0042995 ] ) ] . obo:GO_0030033 obo:IAO_0000115 "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microvillus biogenesis" ; oboInOwl:id "GO:0030033" ; a owl:Class ; rdfs:label "microvillus assembly" ; rdfs:subClassOf obo:GO_0032528, obo:GO_0120031, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005902 ] ) ] . obo:GO_0030036 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23114"^^xsd:anyURI ; oboInOwl:hasExactSynonym "actin cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "actin cytoskeleton organization and biogenesis", "actin modulating activity" ; oboInOwl:id "GO:0030036" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "actin cytoskeleton organization" ; rdfs:subClassOf obo:GO_0007010, obo:GO_0030029, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0015629 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0015629 ] ) ] . obo:GO_0030037 obo:IAO_0000115 "The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs." ; oboInOwl:hasExactSynonym "actin filament reorganisation involved in cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "actin filament reorganization during cell cycle" ; oboInOwl:id "GO:0030037" ; a owl:Class ; rdfs:label "actin filament reorganization involved in cell cycle" ; rdfs:subClassOf obo:GO_0022402, obo:GO_0090527 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0090527 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0030048 obo:IAO_0000115 "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030048" ; a owl:Class ; rdfs:label "actin filament-based movement" ; rdfs:subClassOf obo:GO_0030029 . obo:GO_0030050 obo:IAO_0000115 "Movement of a vesicle along an actin filament, mediated by motor proteins." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030050" ; a owl:Class ; rdfs:label "vesicle transport along actin filament" ; rdfs:subClassOf obo:GO_0030048, obo:GO_0099515, obo:GO_0099518 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005884 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0030054 obo:IAO_0000115 "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "Wikipedia:Cell_junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030054" ; oboInOwl:inSubset go:goslim_agr, go:goslim_drosophila, go:goslim_flybase_ribbon ; a owl:Class ; rdfs:label "cell junction" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] . obo:GO_0030071 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030071" ; a owl:Class ; rdfs:label "regulation of mitotic metaphase/anaphase transition" ; rdfs:subClassOf obo:GO_1901990, obo:GO_1902099, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007091 ] ) ] . obo:GO_0030072 obo:IAO_0000115 "The regulated release of a peptide hormone from a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030072" ; a owl:Class ; rdfs:label "peptide hormone secretion" ; rdfs:subClassOf obo:GO_0002790, obo:GO_0046879, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25905 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25905 ] ) ] . obo:GO_0030073 obo:IAO_0000115 "The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030073" ; a owl:Class ; rdfs:label "insulin secretion" ; rdfs:subClassOf obo:GO_0009306, obo:GO_0030072, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_6072 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000009054 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_6072 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000009054 ] ) ] . obo:GO_0030097 obo:IAO_0000115 "The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22178"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Haematopoiesis" ; oboInOwl:hasExactSynonym "blood cell biosynthesis", "blood cell formation", "haemopoiesis", "hematopoiesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030097" ; a owl:Class ; rdfs:label "hemopoiesis" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000988 ] ) ] . obo:GO_0030098 obo:IAO_0000115 "The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." ; oboInOwl:hasAlternativeId "GO:0046650" ; oboInOwl:hasExactSynonym "lymphocyte cell differentiation", "lymphocytic blood cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lymphocyte development" ; oboInOwl:id "GO:0030098" ; a owl:Class ; rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "lymphocyte differentiation" ; rdfs:subClassOf obo:GO_0046649, obo:GO_1903131, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000542 ] ) ] . obo:GO_0030099 obo:IAO_0000115 "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030099" ; a owl:Class ; rdfs:label "myeloid cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030097 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000763 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000763 ] ) ] . obo:GO_0030100 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of endocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030100" ; a owl:Class ; rdfs:label "regulation of endocytosis" ; rdfs:subClassOf obo:GO_0051128, obo:GO_0060627, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006897 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006897 ] ) ] . obo:GO_0030104 obo:IAO_0000115 "OBSOLETE. Any process involved in the maintenance of an internal steady state of water within an organism or cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24726"^^xsd:anyURI ; oboInOwl:consider "GO:0003091", "GO:0009992", "GO:0050891" ; oboInOwl:hasAlternativeId "GO:0018987" ; oboInOwl:hasDbXref "Wikipedia:Osmoregulation" ; oboInOwl:hasExactSynonym "regulation of osmotic pressure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "osmoregulation" ; oboInOwl:id "GO:0030104" ; a owl:Class ; rdfs:comment "The reason for obsoletion is that this term does not specify whether the process is intracellular or organism-level." ; rdfs:label "obsolete water homeostasis" ; owl:deprecated true . obo:GO_0030133 obo:IAO_0000115 "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." ; oboInOwl:hasDbXref "NIF_Subcellular:sao885490876" ; oboInOwl:hasExactSynonym "constitutive secretory pathway transport vesicle" ; oboInOwl:hasNarrowSynonym "Golgi to vacuole transport vesicle", "Golgi-vacuole transport vesicle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "secretory vesicle" ; oboInOwl:id "GO:0030133" ; a owl:Class ; rdfs:comment "Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'." ; rdfs:label "transport vesicle" ; rdfs:subClassOf obo:GO_0031410, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0030139 obo:IAO_0000115 "A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1362520468" ; oboInOwl:hasExactSynonym "endocytotic transport vesicle", "endocytotic vesicle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030139" ; a owl:Class ; rdfs:label "endocytic vesicle" ; rdfs:subClassOf obo:GO_0031410 . obo:GO_0030141 obo:IAO_0000115 "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules." ; obo:RO_0002161 obo:NCBITaxon_4890 ; oboInOwl:hasBroadSynonym "secretory vesicle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030141" ; a owl:Class ; rdfs:comment "Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'transport vesicle ; GO:0030133'." ; rdfs:label "secretory granule" ; rdfs:subClassOf obo:GO_0099503, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4890 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ] . obo:GO_0030154 obo:IAO_0000115 "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Cellular_differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030154" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_plant ; a owl:Class ; rdfs:label "cell differentiation" ; rdfs:subClassOf obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000000 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048869 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000000 ] ) ] . obo:GO_0030155 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell adhesion receptor regulator activity" ; oboInOwl:id "GO:0030155" ; a owl:Class ; rdfs:label "regulation of cell adhesion" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007155 ] ) ] . obo:GO_0030163 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0044254", "GO:0044257" ; oboInOwl:hasDbXref "Wikipedia:Protein_catabolism" ; oboInOwl:hasExactSynonym "cellular protein breakdown", "cellular protein catabolic process", "cellular protein catabolism", "cellular protein degradation", "protein breakdown", "protein catabolism", "protein degradation" ; oboInOwl:hasNarrowSynonym "multicellular organismal protein catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pheromone catabolic process", "pheromone catabolism" ; oboInOwl:id "GO:0030163" ; oboInOwl:inSubset go:goslim_candida, go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:comment "This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children." ; rdfs:label "protein catabolic process" ; rdfs:subClassOf obo:GO_0009057, obo:GO_0019538, obo:GO_1901565, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0030174 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase." ; oboInOwl:hasBroadSynonym "regulation of DNA replication initiation" ; oboInOwl:hasExactSynonym "DNA replication licencing", "DNA replication licensing", "regulation of DNA-dependent DNA replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030174" ; a owl:Class ; rdfs:label "regulation of DNA-templated DNA replication initiation" ; rdfs:subClassOf obo:GO_0090329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006270 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006270 ] ) ] . obo:GO_0030182 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a neuron." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030182" ; a owl:Class ; rdfs:label "neuron differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048699 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000540 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0030198 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix." ; oboInOwl:hasExactSynonym "extracellular matrix organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "extracellular matrix organization and biogenesis" ; oboInOwl:id "GO:0030198" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic ; a owl:Class ; rdfs:label "extracellular matrix organization" ; rdfs:subClassOf obo:GO_0043062, obo:GO_0045229, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031012 ] ) ] . obo:GO_0030199 obo:IAO_0000115 "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasExactSynonym "collagen fibril organisation", "fibrillar collagen organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030199" ; a owl:Class ; rdfs:label "collagen fibril organization" ; rdfs:subClassOf obo:GO_0030198, obo:GO_0097435, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0098643 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0098643 ] ) ] . obo:GO_0030203 obo:IAO_0000115 "The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars." ; oboInOwl:hasExactSynonym "glycosaminoglycan metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030203" ; a owl:Class ; rdfs:label "glycosaminoglycan metabolic process" ; rdfs:subClassOf obo:GO_0006022, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_18085 ] ) ] . obo:GO_0030212 obo:IAO_0000115 "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." ; oboInOwl:hasExactSynonym "hyaluronan metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030212" ; a owl:Class ; rdfs:label "hyaluronan metabolic process" ; rdfs:subClassOf obo:GO_1903510, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_16336 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_16336 ] ) ] . obo:GO_0030213 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." ; oboInOwl:hasExactSynonym "hyaluronan anabolism", "hyaluronan biosynthesis", "hyaluronan formation", "hyaluronan synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030213" ; a owl:Class ; rdfs:label "hyaluronan biosynthetic process" ; rdfs:subClassOf obo:GO_0006024, obo:GO_0030212, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16336 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16336 ] ) ] . obo:GO_0030214 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine." ; oboInOwl:hasExactSynonym "hyaluronan breakdown", "hyaluronan catabolism", "hyaluronan degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030214" ; a owl:Class ; rdfs:label "hyaluronan catabolic process" ; rdfs:subClassOf obo:GO_0006027, obo:GO_0030212, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16336 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16336 ] ) ] . obo:GO_0030217 obo:IAO_0000115 "The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex." ; oboInOwl:hasAlternativeId "GO:0042112", "GO:0046652" ; oboInOwl:hasExactSynonym "T lymphocyte differentiation", "T-cell differentiation", "T-lymphocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "T cell development" ; oboInOwl:id "GO:0030217" ; a owl:Class ; rdfs:comment "Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "T cell differentiation" ; rdfs:subClassOf obo:GO_0030098, obo:GO_0042110, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0030218 obo:IAO_0000115 "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte." ; oboInOwl:hasDbXref "Wikipedia:Erythropoiesis" ; oboInOwl:hasExactSynonym "RBC differentiation", "erythrocyte cell differentiation", "erythropoiesis", "red blood cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030218" ; a owl:Class ; rdfs:label "erythrocyte differentiation" ; rdfs:subClassOf obo:GO_0030099, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034101 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000232 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000232 ] ) ] . obo:GO_0030219 obo:IAO_0000115 "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte." ; oboInOwl:hasExactSynonym "megakaryocyte cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030219" ; a owl:Class ; rdfs:label "megakaryocyte differentiation" ; rdfs:subClassOf obo:GO_0030099, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000556 ] ) ] . obo:GO_0030239 obo:IAO_0000115 "Formation of myofibrils, the repeating units of striated muscle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030239" ; a owl:Class ; rdfs:label "myofibril assembly" ; rdfs:subClassOf obo:GO_0010927, obo:GO_0031032, obo:GO_0097435, obo:GO_0140694, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055002 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0030016 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0030016 ] ) ] . obo:GO_0030246 obo:IAO_0000115 "Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates." ; oboInOwl:hasAlternativeId "GO:0005529" ; oboInOwl:hasExactSynonym "sugar binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "selectin" ; oboInOwl:id "GO:0030246" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "carbohydrate binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16646 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16646 ] ) ] . obo:GO_0030247 obo:IAO_0000115 "Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically." ; oboInOwl:hasAlternativeId "GO:0002506" ; oboInOwl:hasNarrowSynonym "polysaccharide assembly with MHC class II protein complex" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0030247" ; a owl:Class ; rdfs:label "polysaccharide binding" ; rdfs:subClassOf obo:GO_0030246, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18154 ] ) ] . obo:GO_0030261 obo:IAO_0000115 "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." ; oboInOwl:hasAlternativeId "GO:0000068" ; oboInOwl:hasBroadSynonym "DNA condensation" ; oboInOwl:hasExactSynonym "eukaryotic chromosome condensation", "nuclear chromosome condensation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030261" ; a owl:Class ; rdfs:label "chromosome condensation" ; rdfs:subClassOf obo:GO_0051276 . obo:GO_0030262 obo:IAO_0000115 "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis." ; oboInOwl:hasNarrowSynonym "apoptotic nuclear change" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030262" ; a owl:Class ; rdfs:label "apoptotic nuclear changes" ; rdfs:subClassOf obo:GO_0006921 . obo:GO_0030263 obo:IAO_0000115 "The compaction of chromatin during apoptosis." ; oboInOwl:hasDbXref "Wikipedia:Pyknosis" ; oboInOwl:hasExactSynonym "pyknosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030263" ; a owl:Class ; rdfs:label "apoptotic chromosome condensation" ; rdfs:subClassOf obo:GO_0030261, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030262 ] . obo:GO_0030264 obo:IAO_0000115 "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA." ; oboInOwl:hasExactSynonym "apoptotic nuclear fragmentation", "nucleus fragmentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear fragmentation during apoptosis" ; oboInOwl:id "GO:0030264" ; a owl:Class ; rdfs:label "nuclear fragmentation involved in apoptotic nuclear change" ; rdfs:subClassOf obo:GO_0071763, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030262 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071763 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030262 ] ) ] . obo:GO_0030278 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." ; oboInOwl:hasExactSynonym "regulation of bone biosynthesis", "regulation of bone formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030278" ; a owl:Class ; rdfs:label "regulation of ossification" ; rdfs:subClassOf obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001503 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001503 ] ) ] . obo:GO_0030279 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." ; oboInOwl:hasExactSynonym "down regulation of ossification", "down-regulation of ossification", "downregulation of ossification", "negative regulation of bone biosynthesis", "negative regulation of bone formation" ; oboInOwl:hasNarrowSynonym "inhibition of ossification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030279" ; a owl:Class ; rdfs:label "negative regulation of ossification" ; rdfs:subClassOf obo:GO_0030278, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001503 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001503 ] ) ] . obo:GO_0030307 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, extent or direction of cell growth." ; oboInOwl:hasExactSynonym "up regulation of cell growth", "up-regulation of cell growth", "upregulation of cell growth" ; oboInOwl:hasNarrowSynonym "activation of cell growth", "stimulation of cell growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030307" ; a owl:Class ; rdfs:label "positive regulation of cell growth" ; rdfs:subClassOf obo:GO_0001558, obo:GO_0045927, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016049 ] ) ] . obo:GO_0030308 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." ; oboInOwl:hasExactSynonym "down regulation of cell growth", "down-regulation of cell growth", "downregulation of cell growth" ; oboInOwl:hasNarrowSynonym "inhibition of cell growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030308" ; a owl:Class ; rdfs:label "negative regulation of cell growth" ; rdfs:subClassOf obo:GO_0001558, obo:GO_0045926, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016049 ] ) ] . obo:GO_0030312 obo:IAO_0000115 "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030312" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:comment "The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'." ; rdfs:label "external encapsulating structure" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000000 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071944 ] . obo:GO_0030317 obo:IAO_0000115 "The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm." ; oboInOwl:hasAlternativeId "GO:0097724", "GO:1905419" ; oboInOwl:hasBroadSynonym "sperm motility", "sperm movement" ; oboInOwl:hasDbXref "Wikipedia:Sperm_motility" ; oboInOwl:hasExactSynonym "flagellated sperm movement", "sperm flagellum movement", "sperm flagellum movement involved in flagellated sperm motility", "sperm flagellum movement involved in flagellated sperm movement" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030317" ; a owl:Class ; rdfs:label "flagellated sperm motility" ; rdfs:subClassOf obo:GO_0060285, obo:GO_0060294, obo:GO_0097722 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060285 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000019 ] ) ] . obo:GO_0030323 obo:IAO_0000115 "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030323" ; a owl:Class ; rdfs:label "respiratory tube development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000117 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000117 ] ) ] . obo:GO_0030324 obo:IAO_0000115 "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030324" ; a owl:Class ; rdfs:label "lung development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030323 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060541 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:GO_0030334 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell migration." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030334" ; a owl:Class ; rdfs:label "regulation of cell migration" ; rdfs:subClassOf obo:GO_2000145, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016477 ] ) ] . obo:GO_0030335 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell migration." ; oboInOwl:hasExactSynonym "up regulation of cell migration", "up-regulation of cell migration", "upregulation of cell migration" ; oboInOwl:hasNarrowSynonym "activation of cell migration", "stimulation of cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030335" ; a owl:Class ; rdfs:label "positive regulation of cell migration" ; rdfs:subClassOf obo:GO_0030334, obo:GO_2000147, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016477 ] ) ] . obo:GO_0030336 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." ; oboInOwl:hasExactSynonym "down regulation of cell migration", "down-regulation of cell migration", "downregulation of cell migration" ; oboInOwl:hasNarrowSynonym "inhibition of cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030336" ; a owl:Class ; rdfs:label "negative regulation of cell migration" ; rdfs:subClassOf obo:GO_0030334, obo:GO_2000146, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016477 ] ) ] . obo:GO_0030397 obo:IAO_0000115 "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." ; oboInOwl:hasExactSynonym "membrane breakdown", "membrane catabolism", "membrane degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030397" ; a owl:Class ; rdfs:label "membrane disassembly" ; rdfs:subClassOf obo:GO_0022411, obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0030421 obo:IAO_0000115 "The expulsion of feces from the rectum." ; oboInOwl:hasDbXref "Wikipedia:Defecation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030421" ; a owl:Class ; rdfs:label "defecation" ; rdfs:subClassOf obo:GO_0007588, obo:GO_0022600 . obo:GO_0030424 obo:IAO_0000115 "The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1770195789", "Wikipedia:Axon" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030424" ; a owl:Class ; rdfs:label "axon" ; rdfs:subClassOf obo:GO_0043005 . obo:GO_0030425 obo:IAO_0000115 "A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1211023249", "Wikipedia:Dendrite" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030425" ; a owl:Class ; rdfs:label "dendrite" ; rdfs:subClassOf obo:GO_0043005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0097447 ] . obo:GO_0030432 obo:IAO_0000115 "A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards." ; oboInOwl:hasDbXref "Wikipedia:Peristalsis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030432" ; a owl:Class ; rdfs:label "peristalsis" ; rdfs:subClassOf obo:GO_0014821 . obo:GO_0030473 obo:IAO_0000115 "The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins." ; oboInOwl:hasAlternativeId "GO:0000065" ; oboInOwl:hasBroadSynonym "nuclear movement, microtubule-mediated", "nucleus migration" ; oboInOwl:hasExactSynonym "microtubule cytoskeleton-dependent nuclear positioning", "microtubule cytoskeleton-dependent nucleus positioning", "microtubule-dependent nuclear positioning", "microtubule-dependent nucleus positioning", "microtubule-mediated nuclear migration", "nuclear migration, microtubule-mediated", "transport of nucleus by microtubules", "transport of nucleus, microtubule-mediated" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030473" ; a owl:Class ; rdfs:label "nuclear migration along microtubule" ; rdfs:subClassOf obo:GO_0007097, obo:GO_0072384, [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0015630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007097 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0015630 ] ) ] . obo:GO_0030485 obo:IAO_0000115 "The contractile fiber of smooth muscle cells." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030485" ; a owl:Class ; rdfs:label "smooth muscle contractile fiber" ; rdfs:subClassOf obo:GO_0043292, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000192 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043292 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000192 ] ) ] . obo:GO_0030516 obo:IAO_0000115 "Any process that modulates the rate, direction or extent of axon extension." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030516" ; a owl:Class ; rdfs:label "regulation of axon extension" ; rdfs:subClassOf obo:GO_0048638, obo:GO_0061387, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048675 ] ) ] . obo:GO_0030517 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth." ; oboInOwl:hasExactSynonym "down regulation of axon extension", "down-regulation of axon extension", "downregulation of axon extension" ; oboInOwl:hasNarrowSynonym "inhibition of axon extension" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030517" ; a owl:Class ; rdfs:label "negative regulation of axon extension" ; rdfs:subClassOf obo:GO_0030308, obo:GO_0030516, obo:GO_0048640, obo:GO_0050771, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048675 ] ) ] . obo:GO_0030534 obo:IAO_0000115 "Behavior in a fully developed and mature organism." ; oboInOwl:hasExactSynonym "adult behavioral response to stimulus", "adult behaviour", "adult behavioural response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030534" ; a owl:Class ; rdfs:comment "See also the biological process term 'behavior ; GO:0007610'." ; rdfs:label "adult behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0030537 obo:IAO_0000115 "Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics." ; oboInOwl:hasAlternativeId "GO:0017037" ; oboInOwl:hasExactSynonym "larval behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030537" ; a owl:Class ; rdfs:comment "See also the biological process term 'behavior ; GO:0007610'." ; rdfs:label "larval behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0030539 obo:IAO_0000115 "The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure." ; oboInOwl:hasExactSynonym "male genital development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030539" ; a owl:Class ; rdfs:label "male genitalia development" ; rdfs:subClassOf obo:GO_0048806, obo:GO_0061458, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046661 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000079 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000079 ] ) ] . obo:GO_0030573 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile." ; oboInOwl:hasAlternativeId "GO:0019613" ; oboInOwl:hasDbXref "MetaCyc:7ALPHADEHYDROX-PWY" ; oboInOwl:hasExactSynonym "bile acid breakdown", "bile acid catabolism", "bile acid degradation" ; oboInOwl:hasNarrowSynonym "bile acid 7alpha-dehydroxylation pathway", "cholate catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030573" ; a owl:Class ; rdfs:label "bile acid catabolic process" ; rdfs:subClassOf obo:GO_0008206, obo:GO_0072329, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36235 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36235 ] ) ] . obo:GO_0030574 obo:IAO_0000115 "The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells." ; oboInOwl:hasExactSynonym "collagen breakdown", "collagen catabolism", "collagen degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030574" ; a owl:Class ; rdfs:label "collagen catabolic process" ; rdfs:subClassOf obo:GO_0009056, obo:GO_0032963, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005581 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005581 ] ) ] . obo:GO_0030588 obo:IAO_0000115 "Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030588" ; a owl:Class ; rdfs:label "pseudocleavage" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ] . obo:GO_0030590 obo:IAO_0000115 "A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030590" ; a owl:Class ; rdfs:label "first cell cycle pseudocleavage" ; rdfs:subClassOf obo:GO_0030588 . obo:GO_0030595 obo:IAO_0000115 "The movement of a leukocyte in response to an external stimulus." ; oboInOwl:hasExactSynonym "immune cell chemotaxis", "leucocyte chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030595" ; a owl:Class ; rdfs:label "leukocyte chemotaxis" ; rdfs:subClassOf obo:GO_0050900, obo:GO_0060326 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006935 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0030641 obo:IAO_0000115 "Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment." ; oboInOwl:hasExactSynonym "cellular hydrogen ion homeostasis", "proton homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030641" ; a owl:Class ; rdfs:label "regulation of cellular pH" ; rdfs:subClassOf obo:GO_0006885, obo:GO_0030003 . obo:GO_0030642 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24514"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "sulphate ion homeostasis" ; oboInOwl:hasExactSynonym "cellular sulfate ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030642" ; a owl:Class ; rdfs:label "intracellular sulfate ion homeostasis" ; rdfs:subClassOf obo:GO_0055063, obo:GO_0055082 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055082 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_16189 ] ) ] . obo:GO_0030643 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell." ; oboInOwl:hasExactSynonym "cellular phosphate ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030643" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "intracellular phosphate ion homeostasis" ; rdfs:subClassOf obo:GO_0055062, obo:GO_0055082 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019725 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_35780 ] ) ] . obo:GO_0030658 obo:IAO_0000115 "The lipid bilayer surrounding a transport vesicle." ; oboInOwl:hasBroadSynonym "secretory vesicle membrane" ; oboInOwl:hasExactSynonym "constitutive secretory pathway transport vesicle membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030658" ; a owl:Class ; rdfs:label "transport vesicle membrane" ; rdfs:subClassOf obo:GO_0030659, obo:GO_0098588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030133 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0030133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0030133 ] ) ] . obo:GO_0030659 obo:IAO_0000115 "The lipid bilayer surrounding a cytoplasmic vesicle." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030659" ; a owl:Class ; rdfs:label "cytoplasmic vesicle membrane" ; rdfs:subClassOf obo:GO_0012506, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031410 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031410 ] ) ] . obo:GO_0030660 obo:IAO_0000115 "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "Golgi vesicle membrane" ; oboInOwl:id "GO:0030660" ; a owl:Class ; rdfs:label "Golgi-associated vesicle membrane" ; rdfs:subClassOf obo:GO_0030659, obo:GO_0098588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005798 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005798 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005798 ] ) ] . obo:GO_0030666 obo:IAO_0000115 "The lipid bilayer surrounding an endocytic vesicle." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030666" ; a owl:Class ; rdfs:label "endocytic vesicle membrane" ; rdfs:subClassOf obo:GO_0030659, obo:GO_0098588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030139 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0030139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0030139 ] ) ] . obo:GO_0030667 obo:IAO_0000115 "The lipid bilayer surrounding a secretory granule." ; oboInOwl:hasBroadSynonym "secretory vesicle membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030667" ; a owl:Class ; rdfs:label "secretory granule membrane" ; rdfs:subClassOf obo:GO_0030659, obo:GO_0098588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030141 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0030141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0030141 ] ) ] . obo:GO_0030705 obo:IAO_0000115 "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030705" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila ; a owl:Class ; rdfs:label "cytoskeleton-dependent intracellular transport" ; rdfs:subClassOf obo:GO_0046907, [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0099513 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0099513 ] ) ] . obo:GO_0030718 obo:IAO_0000115 "Any process by which an organism or tissue maintains a population of germ-line stem cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030718" ; a owl:Class ; rdfs:label "germ-line stem cell population maintenance" ; rdfs:subClassOf obo:GO_0019827, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098727 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000014 ] ) ] . obo:GO_0030720 obo:IAO_0000115 "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber." ; oboInOwl:hasExactSynonym "establishment and maintenance of oocyte localization in egg chamber", "establishment and maintenance of oocyte position during oogenesis", "oocyte localisation involved in germarium-derived egg chamber formation", "oogenesis, establishment and maintenance of oocyte localization", "oogenesis, oocyte localization" ; oboInOwl:hasNarrowSynonym "oocyte positioning during oogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "oocyte localization during germarium-derived egg chamber formation", "oocyte localization during oogenesis" ; oboInOwl:id "GO:0030720" ; a owl:Class ; rdfs:label "oocyte localization involved in germarium-derived egg chamber formation" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0051674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007293 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_50557 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CL_0000023 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_50557 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CL_0000023 ] ) ] . obo:GO_0030728 obo:IAO_0000115 "The release of a mature ovum/oocyte from an ovary." ; oboInOwl:hasDbXref "Wikipedia:Ovulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030728" ; a owl:Class ; rdfs:label "ovulation" ; rdfs:subClassOf obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] . obo:GO_0030855 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030855" ; a owl:Class ; rdfs:label "epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060429 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000066 ] ) ] . obo:GO_0030856 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030856" ; a owl:Class ; rdfs:label "regulation of epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0045595, obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030855 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030855 ] ) ] . obo:GO_0030857 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of epithelial cell differentiation", "down-regulation of epithelial cell differentiation", "downregulation of epithelial cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of epithelial cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030857" ; a owl:Class ; rdfs:label "negative regulation of epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0030856, obo:GO_0045596, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030855 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030855 ] ) ] . obo:GO_0030858 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of epithelial cell differentiation", "up-regulation of epithelial cell differentiation", "upregulation of epithelial cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of epithelial cell differentiation", "stimulation of epithelial cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030858" ; a owl:Class ; rdfs:label "positive regulation of epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0030856, obo:GO_0045597, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030855 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030855 ] ) ] . obo:GO_0030901 obo:IAO_0000115 "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)." ; oboInOwl:hasExactSynonym "mesencephalon development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030901" ; a owl:Class ; rdfs:label "midbrain development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007420 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001891 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001891 ] ) ] . obo:GO_0030902 obo:IAO_0000115 "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium)." ; oboInOwl:hasExactSynonym "rhombencephalon development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030902" ; a owl:Class ; rdfs:label "hindbrain development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007420 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002028 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002028 ] ) ] . obo:GO_0030903 obo:IAO_0000115 "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030903" ; a owl:Class ; rdfs:label "notochord development" ; rdfs:subClassOf obo:GO_0048568, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002328 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002328 ] ) ] . obo:GO_0030917 obo:IAO_0000115 "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages." ; oboInOwl:hasExactSynonym "MHB development", "isthmic organizer development", "isthmomesencephalic boundary development", "isthmus development", "midbrain-hindbrain orgainizer development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030917" ; a owl:Class ; rdfs:label "midbrain-hindbrain boundary development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007420 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021903 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003052 ] ) ] . obo:GO_0030936 obo:IAO_0000115 "Any collagen trimer that passes through a lipid bilayer membrane." ; oboInOwl:hasExactSynonym "MACIT" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030936" ; a owl:Class ; rdfs:label "transmembrane collagen trimer" ; rdfs:subClassOf obo:GO_0005581, obo:GO_0098797 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005581 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0030951 obo:IAO_0000115 "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030951" ; a owl:Class ; rdfs:label "establishment or maintenance of microtubule cytoskeleton polarity" ; rdfs:subClassOf obo:GO_0000226, obo:GO_0030952 . obo:GO_0030952 obo:IAO_0000115 "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cytoskeleton polarization" ; oboInOwl:id "GO:0030952" ; a owl:Class ; rdfs:label "establishment or maintenance of cytoskeleton polarity" ; rdfs:subClassOf obo:GO_0007010, obo:GO_0007163 . obo:GO_0030968 obo:IAO_0000115 "The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation." ; oboInOwl:hasExactSynonym "ER unfolded protein response", "erUPR" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "SREBP-mediated signalling pathway" ; oboInOwl:id "GO:0030968" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'response to unfolded protein ; GO:0006986', which refers to any response to the presence of unfolded proteins anywhere in the cell or in multicellular organism. Also see 'ER-associated protein catabolic process ; GO:0030433'." ; rdfs:label "endoplasmic reticulum unfolded protein response" ; rdfs:subClassOf obo:GO_0007165, obo:GO_0034976, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034620 ] . obo:GO_0030990 obo:IAO_0000115 "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." ; oboInOwl:hasExactSynonym "intraflagellar transport complex", "intraflagellar transport particle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "IFT complex" ; oboInOwl:id "GO:0030990" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that we deem cilia and microtubule-based flagella to be equivalent." ; rdfs:label "intraciliary transport particle" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0035735 ] . obo:GO_0031012 obo:IAO_0000115 "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." ; oboInOwl:hasAlternativeId "GO:0005578" ; oboInOwl:hasDbXref "NIF_Subcellular:nlx_subcell_20090513", "Wikipedia:Extracellular_matrix" ; oboInOwl:hasExactSynonym "proteinaceous extracellular matrix" ; oboInOwl:hasNarrowSynonym "matrisome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031012" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "extracellular matrix" ; rdfs:subClassOf obo:GO_0030312 ; owl:disjointWith obo:GO_0032991, obo:GO_0043226 . obo:GO_0031016 obo:IAO_0000115 "The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23777"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Pancreas" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031016" ; a owl:Class ; rdfs:label "pancreas development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001264 ] ) ] . obo:GO_0031017 obo:IAO_0000115 "The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031017" ; a owl:Class ; rdfs:label "exocrine pancreas development" ; rdfs:subClassOf obo:GO_0048732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031016 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035272 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055123 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000017 ] ) ] . obo:GO_0031018 obo:IAO_0000115 "The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031018" ; a owl:Class ; rdfs:label "endocrine pancreas development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031016 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035270 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000016 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000016 ] ) ] . obo:GO_0031022 obo:IAO_0000115 "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins." ; oboInOwl:hasExactSynonym "nuclear migration, microfilament-mediated" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031022" ; a owl:Class ; rdfs:label "nuclear migration along microfilament" ; rdfs:subClassOf obo:GO_0007097, obo:GO_0030048, obo:GO_0099515 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007097 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005884 ] ) ] . obo:GO_0031032 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments." ; oboInOwl:hasExactSynonym "actomyosin organization", "actomyosin structure organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "actomyosin structure organization and biogenesis" ; oboInOwl:id "GO:0031032" ; a owl:Class ; rdfs:comment "Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins." ; rdfs:label "actomyosin structure organization" ; rdfs:subClassOf obo:GO_0030036, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0042641 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0042641 ] ) ] . obo:GO_0031076 obo:IAO_0000115 "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure." ; oboInOwl:hasExactSynonym "embryonic eye development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031076" ; a owl:Class ; rdfs:label "embryonic camera-type eye development" ; rdfs:subClassOf obo:GO_0043010, obo:GO_0048568 . obo:GO_0031090 obo:IAO_0000115 "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." ; oboInOwl:hasDbXref "NIF_Subcellular:sao830981606" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "intracellular membrane" ; oboInOwl:id "GO:0031090" ; a owl:Class ; rdfs:label "organelle membrane" ; rdfs:subClassOf obo:GO_0016020, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043227 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043227 ] ) ] . obo:GO_0031109 obo:IAO_0000115 "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23195"^^xsd:anyURI ; oboInOwl:hasExactSynonym "microtubule dynamics" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031109" ; a owl:Class ; rdfs:label "microtubule polymerization or depolymerization" ; rdfs:subClassOf obo:GO_0000226 . obo:GO_0031110 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031110" ; a owl:Class ; rdfs:label "regulation of microtubule polymerization or depolymerization" ; rdfs:subClassOf obo:GO_0070507, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031109 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031109 ] ) ] . obo:GO_0031111 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." ; oboInOwl:hasExactSynonym "down regulation of microtubule polymerization or depolymerization", "down-regulation of microtubule polymerization or depolymerization", "downregulation of microtubule polymerization or depolymerization" ; oboInOwl:hasNarrowSynonym "inhibition of microtubule polymerization or depolymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031111" ; a owl:Class ; rdfs:label "negative regulation of microtubule polymerization or depolymerization" ; rdfs:subClassOf obo:GO_0031110, obo:GO_0051494, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031109 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031109 ] ) ] . obo:GO_0031112 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." ; oboInOwl:hasExactSynonym "up regulation of microtubule polymerization or depolymerization", "up-regulation of microtubule polymerization or depolymerization", "upregulation of microtubule polymerization or depolymerization" ; oboInOwl:hasNarrowSynonym "activation of microtubule polymerization or depolymerization", "stimulation of microtubule polymerization or depolymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031112" ; a owl:Class ; rdfs:label "positive regulation of microtubule polymerization or depolymerization" ; rdfs:subClassOf obo:GO_0031110, obo:GO_0051495, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031109 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031109 ] ) ] . obo:GO_0031113 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of microtubule polymerization." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031113" ; a owl:Class ; rdfs:label "regulation of microtubule polymerization" ; rdfs:subClassOf obo:GO_0031110, obo:GO_0032271, obo:GO_1902903, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046785 ] ) ] . obo:GO_0031114 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of microtubule depolymerization." ; oboInOwl:hasExactSynonym "regulation of microtubule disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031114" ; a owl:Class ; rdfs:label "regulation of microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031110, obo:GO_1901879, obo:GO_1902903, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007019 ] ) ] . obo:GO_0031115 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." ; oboInOwl:hasExactSynonym "down regulation of microtubule polymerization", "down-regulation of microtubule polymerization", "downregulation of microtubule polymerization" ; oboInOwl:hasNarrowSynonym "inhibition of microtubule polymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031115" ; a owl:Class ; rdfs:label "negative regulation of microtubule polymerization" ; rdfs:subClassOf obo:GO_0031111, obo:GO_0031113, obo:GO_0032272, obo:GO_1902904, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046785 ] ) ] . obo:GO_0031116 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." ; oboInOwl:hasExactSynonym "up regulation of microtubule polymerization", "up-regulation of microtubule polymerization", "upregulation of microtubule polymerization" ; oboInOwl:hasNarrowSynonym "activation of microtubule polymerization", "stimulation of microtubule polymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031116" ; a owl:Class ; rdfs:label "positive regulation of microtubule polymerization" ; rdfs:subClassOf obo:GO_0031112, obo:GO_0031113, obo:GO_0032273, obo:GO_1902905, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046785 ] ) ] . obo:GO_0031117 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." ; oboInOwl:hasExactSynonym "microtubule destabilization", "positive regulation of microtubule disassembly", "up regulation of microtubule depolymerization", "up-regulation of microtubule depolymerization", "upregulation of microtubule depolymerization" ; oboInOwl:hasNarrowSynonym "activation of microtubule depolymerization", "positive regulation of microtubule catastrophe", "stimulation of microtubule depolymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031117" ; a owl:Class ; rdfs:label "positive regulation of microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031112, obo:GO_0031114, obo:GO_1901881, obo:GO_1902905, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007019 ] ) ] . obo:GO_0031122 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." ; oboInOwl:hasExactSynonym "cytoplasmic microtubule organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cytoplasmic microtubule organization and biogenesis" ; oboInOwl:id "GO:0031122" ; a owl:Class ; rdfs:label "cytoplasmic microtubule organization" ; rdfs:subClassOf obo:GO_0000226, obo:GO_0097435, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005881 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005881 ] ) ] . obo:GO_0031128 obo:IAO_0000115 "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031128" ; a owl:Class ; rdfs:label "developmental induction" ; rdfs:subClassOf obo:GO_0032502, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0045168 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4895 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0045168 ] ) ] . obo:GO_0031129 obo:IAO_0000115 "Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate." ; oboInOwl:hasExactSynonym "inductive cell-cell signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031129" ; a owl:Class ; rdfs:label "inductive cell-cell signaling" ; rdfs:subClassOf obo:GO_0031128 . obo:GO_0031143 obo:IAO_0000115 "A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21139"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/21141"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Pseudopod" ; oboInOwl:hasExactSynonym "pseudopod", "pseudopodial protrusion" ; oboInOwl:hasNarrowSynonym "axopodium", "lobopodium", "reticulopodium" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031143" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "pseudopodium" ; rdfs:subClassOf obo:GO_0120025 . obo:GO_0031175 obo:IAO_0000115 "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ; oboInOwl:hasNarrowSynonym "neurite biosynthesis", "neurite development", "neurite formation", "neurite growth", "neurite outgrowth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031175" ; a owl:Class ; rdfs:label "neuron projection development" ; rdfs:subClassOf obo:GO_0120036, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0120036 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ] ) ] . obo:GO_0031252 obo:IAO_0000115 "The area of a motile cell closest to the direction of movement." ; oboInOwl:hasExactSynonym "front of cell", "leading edge of cell" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031252" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cell leading edge" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000000 ] . obo:GO_0031253 obo:IAO_0000115 "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "membrane extension", "membrane projection" ; oboInOwl:id "GO:0031253" ; a owl:Class ; rdfs:label "cell projection membrane" ; rdfs:subClassOf obo:GO_0098590, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0120025 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0120025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0120025 ] ) ] . obo:GO_0031256 obo:IAO_0000115 "The portion of the plasma membrane surrounding the leading edge of a motile cell." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031256" ; a owl:Class ; rdfs:label "leading edge membrane" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031252 ] . obo:GO_0031268 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement." ; oboInOwl:hasExactSynonym "pseudopodium organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pseudopodium organization and biogenesis" ; oboInOwl:id "GO:0031268" ; a owl:Class ; rdfs:label "pseudopodium organization" ; rdfs:subClassOf obo:GO_0120036, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031143 ] ) ] . obo:GO_0031269 obo:IAO_0000115 "The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane." ; oboInOwl:hasExactSynonym "pseudopodium extension" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pseudopodium formation" ; oboInOwl:id "GO:0031269" ; a owl:Class ; rdfs:label "pseudopodium assembly" ; rdfs:subClassOf obo:GO_0031268, obo:GO_0120031, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0031143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0031143 ] ) ] . obo:GO_0031270 obo:IAO_0000115 "The myosin-based contraction and retraction of a pseudopodium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031270" ; a owl:Class ; rdfs:label "pseudopodium retraction" ; rdfs:subClassOf obo:GO_0022411, obo:GO_0031268, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0031143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0031143 ] ) ] . obo:GO_0031272 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the assembly of pseudopodia." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of pseudopodium formation" ; oboInOwl:id "GO:0031272" ; a owl:Class ; rdfs:label "regulation of pseudopodium assembly" ; rdfs:subClassOf obo:GO_0120032, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031269 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031269 ] ) ] . obo:GO_0031273 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia." ; oboInOwl:hasNarrowSynonym "inhibition of pseudopodium formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of pseudopodium formation", "down-regulation of pseudopodium formation", "downregulation of pseudopodium formation", "negative regulation of pseudopodium formation" ; oboInOwl:id "GO:0031273" ; a owl:Class ; rdfs:label "negative regulation of pseudopodium assembly" ; rdfs:subClassOf obo:GO_0031272, obo:GO_0120033, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031269 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031269 ] ) ] . obo:GO_0031274 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia." ; oboInOwl:hasNarrowSynonym "activation of pseudopodium formation", "stimulation of pseudopodium formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of pseudopodium formation", "up regulation of pseudopodium formation", "up-regulation of pseudopodium formation", "upregulation of pseudopodium formation" ; oboInOwl:id "GO:0031274" ; a owl:Class ; rdfs:label "positive regulation of pseudopodium assembly" ; rdfs:subClassOf obo:GO_0031272, obo:GO_0120034, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031269 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031269 ] ) ] . obo:GO_0031323 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." ; oboInOwl:hasExactSynonym "regulation of cellular metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031323" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "regulation of cellular metabolic process" ; rdfs:subClassOf obo:GO_0019222, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044237 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044237 ] ) ] . obo:GO_0031324 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." ; oboInOwl:hasExactSynonym "down regulation of cellular metabolic process", "down-regulation of cellular metabolic process", "downregulation of cellular metabolic process", "negative regulation of cellular metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of cellular metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031324" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of cellular metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0031323, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044237 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044237 ] ) ] . obo:GO_0031325 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." ; oboInOwl:hasExactSynonym "positive regulation of cellular metabolism", "up regulation of cellular metabolic process", "up-regulation of cellular metabolic process", "upregulation of cellular metabolic process" ; oboInOwl:hasNarrowSynonym "activation of cellular metabolic process", "stimulation of cellular metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031325" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of cellular metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0031323, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044237 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044237 ] ) ] . obo:GO_0031326 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "regulation of cellular anabolism", "regulation of cellular biosynthesis", "regulation of cellular formation", "regulation of cellular synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031326" ; a owl:Class ; rdfs:label "regulation of cellular biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0031323, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044249 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044249 ] ) ] . obo:GO_0031327 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "down regulation of cellular biosynthetic process", "down-regulation of cellular biosynthetic process", "downregulation of cellular biosynthetic process", "negative regulation of cellular anabolism", "negative regulation of cellular biosynthesis", "negative regulation of cellular formation", "negative regulation of cellular synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of cellular biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031327" ; a owl:Class ; rdfs:label "negative regulation of cellular biosynthetic process" ; rdfs:subClassOf obo:GO_0009890, obo:GO_0031324, obo:GO_0031326, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044249 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044249 ] ) ] . obo:GO_0031328 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "positive regulation of cellular anabolism", "positive regulation of cellular biosynthesis", "positive regulation of cellular formation", "positive regulation of cellular synthesis", "up regulation of cellular biosynthetic process", "up-regulation of cellular biosynthetic process", "upregulation of cellular biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of cellular biosynthetic process", "stimulation of cellular biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031328" ; a owl:Class ; rdfs:label "positive regulation of cellular biosynthetic process" ; rdfs:subClassOf obo:GO_0009891, obo:GO_0031325, obo:GO_0031326, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044249 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044249 ] ) ] . obo:GO_0031329 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "regulation of cellular breakdown", "regulation of cellular catabolism", "regulation of cellular degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031329" ; a owl:Class ; rdfs:label "regulation of cellular catabolic process" ; rdfs:subClassOf obo:GO_0009894, obo:GO_0031323, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044248 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044248 ] ) ] . obo:GO_0031330 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "down regulation of cellular catabolic process", "down-regulation of cellular catabolic process", "downregulation of cellular catabolic process", "negative regulation of cellular breakdown", "negative regulation of cellular catabolism", "negative regulation of cellular degradation" ; oboInOwl:hasNarrowSynonym "inhibition of cellular catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031330" ; a owl:Class ; rdfs:label "negative regulation of cellular catabolic process" ; rdfs:subClassOf obo:GO_0009895, obo:GO_0031324, obo:GO_0031329, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044248 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044248 ] ) ] . obo:GO_0031331 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "positive regulation of cellular breakdown", "positive regulation of cellular catabolism", "positive regulation of cellular degradation", "up regulation of cellular catabolic process", "up-regulation of cellular catabolic process", "upregulation of cellular catabolic process" ; oboInOwl:hasNarrowSynonym "activation of cellular catabolic process", "stimulation of cellular catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031331" ; a owl:Class ; rdfs:label "positive regulation of cellular catabolic process" ; rdfs:subClassOf obo:GO_0009896, obo:GO_0031325, obo:GO_0031329, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044248 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044248 ] ) ] . obo:GO_0031333 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." ; oboInOwl:hasExactSynonym "down regulation of protein complex assembly", "down-regulation of protein complex assembly", "downregulation of protein complex assembly" ; oboInOwl:hasNarrowSynonym "inhibition of protein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of protein complex assembly" ; oboInOwl:id "GO:0031333" ; a owl:Class ; rdfs:label "negative regulation of protein-containing complex assembly" ; rdfs:subClassOf obo:GO_0043254, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0065003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0065003 ] ) ] . obo:GO_0031334 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein complex assembly." ; oboInOwl:hasExactSynonym "up regulation of protein complex assembly", "up-regulation of protein complex assembly", "upregulation of protein complex assembly" ; oboInOwl:hasNarrowSynonym "activation of protein complex assembly", "stimulation of protein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of protein complex assembly" ; oboInOwl:id "GO:0031334" ; a owl:Class ; rdfs:label "positive regulation of protein-containing complex assembly" ; rdfs:subClassOf obo:GO_0043254, obo:GO_0044089, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0065003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0065003 ] ) ] . obo:GO_0031338 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of vesicle fusion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031338" ; a owl:Class ; rdfs:label "regulation of vesicle fusion" ; rdfs:subClassOf obo:GO_0033043, obo:GO_0060627, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006906 ] ) ] . obo:GO_0031339 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." ; oboInOwl:hasExactSynonym "down regulation of vesicle fusion", "down-regulation of vesicle fusion", "downregulation of vesicle fusion" ; oboInOwl:hasNarrowSynonym "inhibition of vesicle fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031339" ; a owl:Class ; rdfs:label "negative regulation of vesicle fusion" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0031338, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006906 ] ) ] . obo:GO_0031340 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of vesicle fusion." ; oboInOwl:hasExactSynonym "up regulation of vesicle fusion", "up-regulation of vesicle fusion", "upregulation of vesicle fusion" ; oboInOwl:hasNarrowSynonym "activation of vesicle fusion", "stimulation of vesicle fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031340" ; a owl:Class ; rdfs:label "positive regulation of vesicle fusion" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0031338, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006906 ] ) ] . obo:GO_0031344 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ; oboInOwl:hasExactSynonym "regulation of cell projection organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cell projection organization and biogenesis" ; oboInOwl:id "GO:0031344" ; a owl:Class ; rdfs:label "regulation of cell projection organization" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030030 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030030 ] ) ] . obo:GO_0031345 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ; oboInOwl:hasExactSynonym "down regulation of cell projection organization", "down-regulation of cell projection organization", "downregulation of cell projection organization", "negative regulation of cell projection organisation" ; oboInOwl:hasNarrowSynonym "inhibition of cell projection organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell projection organization and biogenesis" ; oboInOwl:id "GO:0031345" ; a owl:Class ; rdfs:label "negative regulation of cell projection organization" ; rdfs:subClassOf obo:GO_0031344, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030030 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030030 ] ) ] . obo:GO_0031346 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ; oboInOwl:hasExactSynonym "positive regulation of cell projection organisation", "up regulation of cell projection organization", "up-regulation of cell projection organization", "upregulation of cell projection organization" ; oboInOwl:hasNarrowSynonym "activation of cell projection organization", "stimulation of cell projection organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cell projection organization and biogenesis" ; oboInOwl:id "GO:0031346" ; a owl:Class ; rdfs:label "positive regulation of cell projection organization" ; rdfs:subClassOf obo:GO_0031344, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030030 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030030 ] ) ] . obo:GO_0031347 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a defense response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031347" ; a owl:Class ; rdfs:label "regulation of defense response" ; rdfs:subClassOf obo:GO_0080134, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006952 ] ) ] . obo:GO_0031348 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." ; oboInOwl:hasExactSynonym "down regulation of defense response", "down-regulation of defense response", "downregulation of defense response" ; oboInOwl:hasNarrowSynonym "inhibition of defense response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031348" ; a owl:Class ; rdfs:label "negative regulation of defense response" ; rdfs:subClassOf obo:GO_0031347, obo:GO_0048585, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006952 ] ) ] . obo:GO_0031349 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a defense response." ; oboInOwl:hasExactSynonym "up regulation of defense response", "up-regulation of defense response", "upregulation of defense response" ; oboInOwl:hasNarrowSynonym "activation of defense response", "stimulation of defense response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031349" ; a owl:Class ; rdfs:label "positive regulation of defense response" ; rdfs:subClassOf obo:GO_0031347, obo:GO_0048584, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006952 ] ) ] . obo:GO_0031399 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031399" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of protein modification process" ; rdfs:subClassOf obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0036211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0036211 ] ) ] . obo:GO_0031400 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ; oboInOwl:hasExactSynonym "down regulation of protein modification", "down-regulation of protein modification", "downregulation of protein modification" ; oboInOwl:hasNarrowSynonym "inhibition of protein modification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031400" ; a owl:Class ; rdfs:label "negative regulation of protein modification process" ; rdfs:subClassOf obo:GO_0031399, obo:GO_0051248, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0036211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0036211 ] ) ] . obo:GO_0031401 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ; oboInOwl:hasExactSynonym "up regulation of protein modification", "up-regulation of protein modification", "upregulation of protein modification" ; oboInOwl:hasNarrowSynonym "activation of protein modification", "stimulation of protein modification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031401" ; a owl:Class ; rdfs:label "positive regulation of protein modification process" ; rdfs:subClassOf obo:GO_0031399, obo:GO_0051247, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0036211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0036211 ] ) ] . obo:GO_0031406 obo:IAO_0000115 "Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-)." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0031406" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "carboxylic acid binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_29067 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_29067 ] ) ] . obo:GO_0031410 obo:IAO_0000115 "A vesicle found in the cytoplasm of a cell." ; oboInOwl:hasAlternativeId "GO:0016023" ; oboInOwl:hasDbXref "NIF_Subcellular:sao180601769" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cytoplasmic membrane bounded vesicle", "cytoplasmic membrane-enclosed vesicle", "cytoplasmic, membrane-bounded vesicle" ; oboInOwl:id "GO:0031410" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_generic, go:goslim_mouse, go:goslim_yeast ; a owl:Class ; rdfs:label "cytoplasmic vesicle" ; rdfs:subClassOf obo:GO_0097708, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031982 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0031430 obo:IAO_0000115 "The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines." ; oboInOwl:hasBroadSynonym "midline" ; oboInOwl:hasDbXref "Wikipedia:Sarcomere#bands" ; oboInOwl:hasExactSynonym "M disc", "mesophragma" ; oboInOwl:hasNarrowSynonym "M line" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031430" ; a owl:Class ; rdfs:label "M band" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031672 ] . obo:GO_0031468 obo:IAO_0000115 "The reformation of the nuclear membranes following their breakdown in the context of a normal process." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20636"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear envelope reassembly" ; oboInOwl:id "GO:0031468" ; a owl:Class ; rdfs:label "nuclear membrane reassembly" ; rdfs:subClassOf obo:GO_0071709, obo:GO_0071763 . obo:GO_0031503 obo:IAO_0000115 "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0034629" ; oboInOwl:hasExactSynonym "establishment and maintenance of protein complex localization", "protein complex localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular protein complex localisation", "cellular protein complex localization", "cellular protein-containing complex localization", "establishment and maintenance of cellular protein complex localization", "protein complex localization" ; oboInOwl:id "GO:0031503" ; a owl:Class ; rdfs:label "protein-containing complex localization" ; rdfs:subClassOf obo:GO_0051179, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0032991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0032991 ] ) ] . obo:GO_0031514 obo:IAO_0000115 "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell." ; oboInOwl:hasAlternativeId "GO:0009434", "GO:0031512" ; oboInOwl:hasExactSynonym "motile cilia" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "microtubule-based flagellum", "motile primary cilia", "motile primary cilium", "motile secondary cilium", "nodal cilium" ; oboInOwl:id "GO:0031514" ; a owl:Class ; rdfs:label "motile cilium" ; rdfs:subClassOf obo:GO_0005929, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0003341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005929 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0003341 ] ) ] . obo:GO_0031532 obo:IAO_0000115 "A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins." ; oboInOwl:hasAlternativeId "GO:0007012" ; oboInOwl:hasExactSynonym "actin cytoskeleton remodeling", "actin cytoskeleton reorganisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031532" ; a owl:Class ; rdfs:label "actin cytoskeleton reorganization" ; rdfs:subClassOf obo:GO_0030036 . obo:GO_0031570 obo:IAO_0000115 "A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072401" ; oboInOwl:hasExactSynonym "DNA integrity checkpoint", "signal transduction involved in DNA integrity checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031570" ; a owl:Class ; rdfs:label "DNA integrity checkpoint signaling" ; rdfs:subClassOf obo:GO_0000075 . obo:GO_0031573 obo:IAO_0000115 "A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072428" ; oboInOwl:hasBroadSynonym "S-phase checkpoint" ; oboInOwl:hasExactSynonym "intra-S DNA damage checkpoint", "mitotic intra-S DNA damage checkpoint", "signal transduction involved in intra-S DNA damage checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031573" ; a owl:Class ; rdfs:label "mitotic intra-S DNA damage checkpoint signaling" ; rdfs:subClassOf obo:GO_0044773, [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000084 ] . obo:GO_0031577 obo:IAO_0000115 "A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072416" ; oboInOwl:hasDbXref "Wikipedia:Spindle_checkpoint" ; oboInOwl:hasExactSynonym "signal transduction involved in spindle checkpoint", "spindle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031577" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to choose either a mitotic or meiotic child term." ; rdfs:label "spindle checkpoint signaling" ; rdfs:subClassOf obo:GO_0000075 . obo:GO_0031594 obo:IAO_0000115 "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1124888485", "Wikipedia:Neuromuscular_junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "NMJ", "motor endplate" ; oboInOwl:id "GO:0031594" ; a owl:Class ; rdfs:comment "In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT." ; rdfs:label "neuromuscular junction" ; rdfs:subClassOf obo:GO_0045202, [ a owl:Restriction ; owl:onProperty obo:RO_0002131 ; owl:someValuesFrom obo:CL_0000100 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002131 ; owl:someValuesFrom obo:CL_0000187 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045202 [ a owl:Restriction ; owl:onProperty obo:RO_0002131 ; owl:someValuesFrom obo:CL_0000100 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002131 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:GO_0031644 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." ; oboInOwl:hasExactSynonym "regulation of neurological process", "regulation of neurological system process", "regulation of neurophysiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031644" ; a owl:Class ; rdfs:label "regulation of nervous system process" ; rdfs:subClassOf obo:GO_0044057, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050877 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050877 ] ) ] . obo:GO_0031645 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." ; oboInOwl:hasExactSynonym "down regulation of neurological process", "down-regulation of neurological process", "downregulation of neurological process", "negative regulation of neurological process", "negative regulation of neurological system process", "negative regulation of neurophysiological process" ; oboInOwl:hasNarrowSynonym "inhibition of neurological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031645" ; a owl:Class ; rdfs:label "negative regulation of nervous system process" ; rdfs:subClassOf obo:GO_0031644, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050877 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050877 ] ) ] . obo:GO_0031646 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." ; oboInOwl:hasExactSynonym "positive regulation of neurological process", "positive regulation of neurological system process", "positive regulation of neurophysiological process", "up regulation of neurological process", "up-regulation of neurological process", "upregulation of neurological process" ; oboInOwl:hasNarrowSynonym "activation of neurological process", "stimulation of neurological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031646" ; a owl:Class ; rdfs:label "positive regulation of nervous system process" ; rdfs:subClassOf obo:GO_0031644, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050877 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050877 ] ) ] . obo:GO_0031647 obo:IAO_0000115 "Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031647" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "regulation of protein stability" ; rdfs:subClassOf obo:GO_0065008 . obo:GO_0031667 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031667" ; a owl:Class ; rdfs:label "response to nutrient levels" ; rdfs:subClassOf obo:GO_0009991 . obo:GO_0031672 obo:IAO_0000115 "The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line." ; oboInOwl:hasDbXref "Wikipedia:Sarcomere#bands" ; oboInOwl:hasExactSynonym "A disc", "Q disc", "anisotropic disc", "transverse disc" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031672" ; a owl:Class ; rdfs:label "A band" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030017 ] . obo:GO_0031965 obo:IAO_0000115 "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1687101204" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031965" ; a owl:Class ; rdfs:label "nuclear membrane" ; rdfs:subClassOf obo:GO_0031090, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005635 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0031966 obo:IAO_0000115 "Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1045389829" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031966" ; a owl:Class ; rdfs:label "mitochondrial membrane" ; rdfs:subClassOf obo:GO_0031090, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005740 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0031967 obo:IAO_0000115 "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031967" ; oboInOwl:inSubset go:goslim_mouse ; a owl:Class ; rdfs:label "organelle envelope" ; rdfs:subClassOf obo:GO_0031975, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043227 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043229 ] . obo:GO_0031968 obo:IAO_0000115 "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031968" ; a owl:Class ; rdfs:label "organelle outer membrane" ; rdfs:subClassOf obo:GO_0019867, obo:GO_0098588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031967 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031967 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0031974 obo:IAO_0000115 "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031974" ; a owl:Class ; rdfs:label "membrane-enclosed lumen" ; rdfs:subClassOf obo:GO_0110165 ; owl:disjointWith obo:GO_0045202 . obo:GO_0031975 obo:IAO_0000115 "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031975" ; a owl:Class ; rdfs:label "envelope" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000000 ] . obo:GO_0031981 obo:IAO_0000115 "The volume enclosed by the nuclear inner membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031981" ; a owl:Class ; rdfs:label "nuclear lumen" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] . obo:GO_0031982 obo:IAO_0000115 "Any small, fluid-filled, spherical organelle enclosed by membrane." ; oboInOwl:hasAlternativeId "GO:0031988" ; oboInOwl:hasDbXref "NIF_Subcellular:sao221389602", "Wikipedia:Vesicle_(biology)" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "membrane-bounded vesicle", "membrane-enclosed vesicle" ; oboInOwl:id "GO:0031982" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "vesicle" ; rdfs:subClassOf obo:GO_0043227 . obo:GO_0031987 obo:IAO_0000115 "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ; oboInOwl:hasExactSynonym "locomotion during locomotory behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031987" ; a owl:Class ; rdfs:label "locomotion involved in locomotory behavior" ; rdfs:subClassOf obo:GO_0040011, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007626 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040011 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007626 ] ) ] . obo:GO_0032024 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin." ; oboInOwl:hasExactSynonym "up regulation of insulin secretion", "up-regulation of insulin secretion", "upregulation of insulin secretion" ; oboInOwl:hasNarrowSynonym "activation of insulin secretion", "stimulation of insulin secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032024" ; a owl:Class ; rdfs:label "positive regulation of insulin secretion" ; rdfs:subClassOf obo:GO_0050714, obo:GO_0050796, obo:GO_0090277, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030073 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030073 ] ) ] . obo:GO_0032042 obo:IAO_0000115 "The chemical reactions and pathways involving mitochondrial DNA." ; oboInOwl:hasExactSynonym "mitochondrial DNA metabolism", "mtDNA metabolic process", "mtDNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032042" ; a owl:Class ; rdfs:label "mitochondrial DNA metabolic process" ; rdfs:subClassOf obo:GO_0006259, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000002 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006259 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0032052 obo:IAO_0000115 "Binding to a bile acid, a steroid carboxylic acids occurring in bile." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0032052" ; a owl:Class ; rdfs:label "bile acid binding" ; rdfs:subClassOf obo:GO_0033293, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_36235 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_36235 ] ) ] . obo:GO_0032055 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress." ; oboInOwl:hasExactSynonym "down regulation of translation in response to stress", "down-regulation of translation in response to stress", "downregulation of translation in response to stress" ; oboInOwl:hasNarrowSynonym "inhibition of translation in response to stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032055" ; a owl:Class ; rdfs:label "negative regulation of translation in response to stress" ; rdfs:subClassOf obo:GO_0017148, obo:GO_0043555 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032056 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress." ; oboInOwl:hasExactSynonym "up regulation of translation in response to stress", "up-regulation of translation in response to stress", "upregulation of translation in response to stress" ; oboInOwl:hasNarrowSynonym "activation of translation in response to stress", "stimulation of translation in response to stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032056" ; a owl:Class ; rdfs:label "positive regulation of translation in response to stress" ; rdfs:subClassOf obo:GO_0043555, obo:GO_0045727 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032057 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress." ; oboInOwl:hasExactSynonym "down regulation of translation initiation in response to stress", "down-regulation of translation initiation in response to stress", "downregulation of translation initiation in response to stress" ; oboInOwl:hasNarrowSynonym "inhibition of translation initiation in response to stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032057" ; a owl:Class ; rdfs:label "negative regulation of translational initiation in response to stress" ; rdfs:subClassOf obo:GO_0045947, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006950 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006950 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006413 ] ) ] . obo:GO_0032058 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress." ; oboInOwl:hasExactSynonym "up regulation of translation initiation in response to stress", "up-regulation of translation initiation in response to stress", "upregulation of translation initiation in response to stress" ; oboInOwl:hasNarrowSynonym "activation of translation initiation in response to stress", "stimulation of translation initiation in response to stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032058" ; a owl:Class ; rdfs:label "positive regulation of translational initiation in response to stress" ; rdfs:subClassOf obo:GO_0045948, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006950 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006950 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006413 ] ) ] . obo:GO_0032059 obo:IAO_0000115 "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." ; oboInOwl:hasDbXref "Wikipedia:Bleb_(cell_biology)" ; oboInOwl:hasExactSynonym "plasma membrane bleb" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032059" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "bleb" ; rdfs:subClassOf obo:GO_0120025 . obo:GO_0032060 obo:IAO_0000115 "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses." ; oboInOwl:hasBroadSynonym "blebbing", "membrane blebbing" ; oboInOwl:hasExactSynonym "cell blebbing", "plasma membrane bleb assembly", "plasma membrane blebbing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032060" ; a owl:Class ; rdfs:label "bleb assembly" ; rdfs:subClassOf obo:GO_0120031, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0032059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0032059 ] ) ] . obo:GO_0032061 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:hasExactSynonym "down regulation of translation in response to osmotic stress", "down-regulation of translation in response to osmotic stress", "downregulation of translation in response to osmotic stress" ; oboInOwl:hasNarrowSynonym "inhibition of translation in response to osmotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032061" ; a owl:Class ; rdfs:label "negative regulation of translation in response to osmotic stress" ; rdfs:subClassOf obo:GO_0032055, obo:GO_0043557 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071470 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032062 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:hasExactSynonym "up regulation of translation in response to osmotic stress", "up-regulation of translation in response to osmotic stress", "upregulation of translation in response to osmotic stress" ; oboInOwl:hasNarrowSynonym "activation of translation in response to osmotic stress", "stimulation of translation in response to osmotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032062" ; a owl:Class ; rdfs:label "positive regulation of translation in response to osmotic stress" ; rdfs:subClassOf obo:GO_0032056, obo:GO_0043557 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071470 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032065 obo:IAO_0000115 "A process in which a protein or protein complex is maintained in a specific location in the cell cortex." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cortical protein anchoring" ; oboInOwl:id "GO:0032065" ; a owl:Class ; rdfs:label "maintenance of protein location in cell cortex" ; rdfs:subClassOf obo:GO_0032507, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005938 ] ) ] . obo:GO_0032069 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclease regulator activity" ; oboInOwl:id "GO:0032069" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of nuclease activity" ; rdfs:subClassOf obo:GO_0051336, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0004518 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0004518 ] ) ] . obo:GO_0032070 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNase regulator", "deoxyribonuclease regulator" ; oboInOwl:id "GO:0032070" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of deoxyribonuclease activity" ; rdfs:subClassOf obo:GO_0032069, obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0004536 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0004536 ] ) ] . obo:GO_0032074 obo:IAO_0000115 "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids." ; oboInOwl:hasExactSynonym "down regulation of nuclease activity", "down-regulation of nuclease activity", "downregulation of nuclease activity" ; oboInOwl:hasNarrowSynonym "inhibition of nuclease activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclease inhibitor" ; oboInOwl:id "GO:0032074" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of nuclease activity" ; rdfs:subClassOf obo:GO_0032069, obo:GO_0045934, obo:GO_0051346, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0004518 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0004518 ] ) ] . obo:GO_0032075 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids." ; oboInOwl:hasExactSynonym "up regulation of nuclease activity", "up-regulation of nuclease activity", "upregulation of nuclease activity" ; oboInOwl:hasNarrowSynonym "activation of nuclease activity", "stimulation of nuclease activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclease activator" ; oboInOwl:id "GO:0032075" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of nuclease activity" ; rdfs:subClassOf obo:GO_0032069, obo:GO_0045935, obo:GO_0051345, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0004518 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0004518 ] ) ] . obo:GO_0032076 obo:IAO_0000115 "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." ; oboInOwl:hasExactSynonym "down regulation of deoxyribonuclease activity", "down-regulation of deoxyribonuclease activity", "downregulation of deoxyribonuclease activity" ; oboInOwl:hasNarrowSynonym "inhibition of deoxyribonuclease activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNase inhibitor", "deoxyribonuclease inhibitor" ; oboInOwl:id "GO:0032076" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of deoxyribonuclease activity" ; rdfs:subClassOf obo:GO_0032070, obo:GO_0032074, obo:GO_0051053, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0004536 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0004536 ] ) ] . obo:GO_0032077 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid." ; oboInOwl:hasExactSynonym "up regulation of deoxyribonuclease activity", "up-regulation of deoxyribonuclease activity", "upregulation of deoxyribonuclease activity" ; oboInOwl:hasNarrowSynonym "activation of deoxyribonuclease activity", "stimulation of deoxyribonuclease activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNase activator", "deoxyribonuclease activator" ; oboInOwl:id "GO:0032077" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of deoxyribonuclease activity" ; rdfs:subClassOf obo:GO_0032070, obo:GO_0032075, obo:GO_0051054, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0004536 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0004536 ] ) ] . obo:GO_0032091 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding." ; oboInOwl:hasExactSynonym "down regulation of protein binding", "down-regulation of protein binding", "downregulation of protein binding" ; oboInOwl:hasNarrowSynonym "inhibition of protein binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032091" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of protein binding" ; rdfs:subClassOf obo:GO_0043393, obo:GO_0051100, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005515 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005515 ] ) ] . obo:GO_0032092 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein binding." ; oboInOwl:hasExactSynonym "up regulation of protein binding", "up-regulation of protein binding", "upregulation of protein binding" ; oboInOwl:hasNarrowSynonym "activation of protein binding", "stimulation of protein binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032092" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of protein binding" ; rdfs:subClassOf obo:GO_0043393, obo:GO_0051099, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005515 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005515 ] ) ] . obo:GO_0032094 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032094" ; a owl:Class ; rdfs:label "response to food" ; rdfs:subClassOf obo:GO_0031667, obo:GO_0042221 . obo:GO_0032095 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to a food stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032095" ; a owl:Class ; rdfs:label "regulation of response to food" ; rdfs:subClassOf obo:GO_0032107, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032094 ] ) ] . obo:GO_0032096 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to food", "down-regulation of response to food", "downregulation of response to food" ; oboInOwl:hasNarrowSynonym "inhibition of response to food" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032096" ; a owl:Class ; rdfs:label "negative regulation of response to food" ; rdfs:subClassOf obo:GO_0032095, obo:GO_0032108, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032094 ] ) ] . obo:GO_0032097 obo:IAO_0000115 "Any process that activates, maintains, or increases the rate of a response to a food stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to food", "up-regulation of response to food", "upregulation of response to food" ; oboInOwl:hasNarrowSynonym "activation of response to food", "stimulation of response to food" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032097" ; a owl:Class ; rdfs:label "positive regulation of response to food" ; rdfs:subClassOf obo:GO_0032095, obo:GO_0032109, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032094 ] ) ] . obo:GO_0032101 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to an external stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032101" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "regulation of response to external stimulus" ; rdfs:subClassOf obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009605 ] ) ] . obo:GO_0032102 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to external stimulus", "down-regulation of response to external stimulus", "downregulation of response to external stimulus" ; oboInOwl:hasNarrowSynonym "inhibition of response to external stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032102" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "negative regulation of response to external stimulus" ; rdfs:subClassOf obo:GO_0032101, obo:GO_0048585, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009605 ] ) ] . obo:GO_0032103 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of a response to an external stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to external stimulus", "up-regulation of response to external stimulus", "upregulation of response to external stimulus" ; oboInOwl:hasNarrowSynonym "activation of response to external stimulus", "stimulation of response to external stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032103" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "positive regulation of response to external stimulus" ; rdfs:subClassOf obo:GO_0032101, obo:GO_0048584, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009605 ] ) ] . obo:GO_0032104 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032104" ; a owl:Class ; rdfs:label "regulation of response to extracellular stimulus" ; rdfs:subClassOf obo:GO_0032101, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009991 ] ) ] . obo:GO_0032105 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to extracellular stimulus", "down-regulation of response to extracellular stimulus", "downregulation of response to extracellular stimulus" ; oboInOwl:hasNarrowSynonym "inhibition of response to extracellular stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032105" ; a owl:Class ; rdfs:label "negative regulation of response to extracellular stimulus" ; rdfs:subClassOf obo:GO_0032102, obo:GO_0032104, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009991 ] ) ] . obo:GO_0032106 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of a response to an extracellular stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to extracellular stimulus", "up-regulation of response to extracellular stimulus", "upregulation of response to extracellular stimulus" ; oboInOwl:hasNarrowSynonym "activation of response to extracellular stimulus", "stimulation of response to extracellular stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032106" ; a owl:Class ; rdfs:label "positive regulation of response to extracellular stimulus" ; rdfs:subClassOf obo:GO_0032103, obo:GO_0032104, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009991 ] ) ] . obo:GO_0032107 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to nutrient levels." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032107" ; a owl:Class ; rdfs:label "regulation of response to nutrient levels" ; rdfs:subClassOf obo:GO_0032104, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031667 ] ) ] . obo:GO_0032108 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels." ; oboInOwl:hasExactSynonym "down regulation of response to nutrient levels", "down-regulation of response to nutrient levels", "downregulation of response to nutrient levels" ; oboInOwl:hasNarrowSynonym "inhibition of response to nutrient levels" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032108" ; a owl:Class ; rdfs:label "negative regulation of response to nutrient levels" ; rdfs:subClassOf obo:GO_0032105, obo:GO_0032107, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031667 ] ) ] . obo:GO_0032109 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a response to nutrient levels." ; oboInOwl:hasExactSynonym "up regulation of response to nutrient levels", "up-regulation of response to nutrient levels", "upregulation of response to nutrient levels" ; oboInOwl:hasNarrowSynonym "activation of response to nutrient levels", "stimulation of response to nutrient levels" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032109" ; a owl:Class ; rdfs:label "positive regulation of response to nutrient levels" ; rdfs:subClassOf obo:GO_0032106, obo:GO_0032107, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031667 ] ) ] . obo:GO_0032153 obo:IAO_0000115 "The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles." ; oboInOwl:hasExactSynonym "cell division plane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032153" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that this term refers to the future site of division in a cell that has not yet divided." ; rdfs:label "cell division site" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0032154 obo:IAO_0000115 "The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm." ; oboInOwl:hasDbXref "Wikipedia:Cleavage_furrow" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032154" ; a owl:Class ; rdfs:comment "While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists." ; rdfs:label "cleavage furrow" ; rdfs:subClassOf obo:GO_0098590, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032153 ] . obo:GO_0032200 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins." ; oboInOwl:hasExactSynonym "chromosome organization, telomeric", "organization of chromosome, telomeric region", "telomere organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "telomere organization and biogenesis" ; oboInOwl:id "GO:0032200" ; oboInOwl:inSubset go:goslim_generic, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:label "telomere organization" ; rdfs:subClassOf obo:GO_0051276 . obo:GO_0032204 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032204" ; a owl:Class ; rdfs:label "regulation of telomere maintenance" ; rdfs:subClassOf obo:GO_0033044, obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000723 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000723 ] ) ] . obo:GO_0032205 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." ; oboInOwl:hasExactSynonym "down regulation of telomere maintenance", "down-regulation of telomere maintenance", "downregulation of telomere maintenance" ; oboInOwl:hasNarrowSynonym "inhibition of telomere maintenance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032205" ; a owl:Class ; rdfs:label "negative regulation of telomere maintenance" ; rdfs:subClassOf obo:GO_0032204, obo:GO_0051053, obo:GO_2001251, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000723 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000723 ] ) ] . obo:GO_0032206 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." ; oboInOwl:hasExactSynonym "up regulation of telomere maintenance", "up-regulation of telomere maintenance", "upregulation of telomere maintenance" ; oboInOwl:hasNarrowSynonym "activation of telomere maintenance", "stimulation of telomere maintenance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032206" ; a owl:Class ; rdfs:label "positive regulation of telomere maintenance" ; rdfs:subClassOf obo:GO_0032204, obo:GO_0051054, obo:GO_2001252, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000723 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000723 ] ) ] . obo:GO_0032222 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032222" ; a owl:Class ; rdfs:label "regulation of synaptic transmission, cholinergic" ; rdfs:subClassOf obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007271 ] ) ] . obo:GO_0032223 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ; oboInOwl:hasExactSynonym "down regulation of synaptic transmission, cholinergic", "down-regulation of synaptic transmission, cholinergic", "downregulation of synaptic transmission, cholinergic" ; oboInOwl:hasNarrowSynonym "inhibition of synaptic transmission, cholinergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032223" ; a owl:Class ; rdfs:label "negative regulation of synaptic transmission, cholinergic" ; rdfs:subClassOf obo:GO_0032222, obo:GO_0050805, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007271 ] ) ] . obo:GO_0032224 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ; oboInOwl:hasExactSynonym "up regulation of synaptic transmission, cholinergic", "up-regulation of synaptic transmission, cholinergic", "upregulation of synaptic transmission, cholinergic" ; oboInOwl:hasNarrowSynonym "activation of synaptic transmission, cholinergic", "stimulation of synaptic transmission, cholinergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032224" ; a owl:Class ; rdfs:label "positive regulation of synaptic transmission, cholinergic" ; rdfs:subClassOf obo:GO_0032222, obo:GO_0050806, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007271 ] ) ] . obo:GO_0032225 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032225" ; a owl:Class ; rdfs:label "regulation of synaptic transmission, dopaminergic" ; rdfs:subClassOf obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001963 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001963 ] ) ] . obo:GO_0032226 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." ; oboInOwl:hasExactSynonym "up regulation of synaptic transmission, dopaminergic", "up-regulation of synaptic transmission, dopaminergic", "upregulation of synaptic transmission, dopaminergic" ; oboInOwl:hasNarrowSynonym "activation of synaptic transmission, dopaminergic", "stimulation of synaptic transmission, dopaminergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032226" ; a owl:Class ; rdfs:label "positive regulation of synaptic transmission, dopaminergic" ; rdfs:subClassOf obo:GO_0032225, obo:GO_0050806, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001963 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001963 ] ) ] . obo:GO_0032227 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine." ; oboInOwl:hasExactSynonym "down regulation of synaptic transmission, dopaminergic", "down-regulation of synaptic transmission, dopaminergic", "downregulation of synaptic transmission, dopaminergic" ; oboInOwl:hasNarrowSynonym "inhibition of synaptic transmission, dopaminergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032227" ; a owl:Class ; rdfs:label "negative regulation of synaptic transmission, dopaminergic" ; rdfs:subClassOf obo:GO_0032225, obo:GO_0050805, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001963 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001963 ] ) ] . obo:GO_0032228 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032228" ; a owl:Class ; rdfs:label "regulation of synaptic transmission, GABAergic" ; rdfs:subClassOf obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051932 ] ) ] . obo:GO_0032229 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ; oboInOwl:hasExactSynonym "down regulation of synaptic transmission, GABAergic", "down-regulation of synaptic transmission, GABAergic", "downregulation of synaptic transmission, GABAergic" ; oboInOwl:hasNarrowSynonym "inhibition of synaptic transmission, GABAergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032229" ; a owl:Class ; rdfs:label "negative regulation of synaptic transmission, GABAergic" ; rdfs:subClassOf obo:GO_0032228, obo:GO_0050805, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051932 ] ) ] . obo:GO_0032230 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ; oboInOwl:hasExactSynonym "up regulation of synaptic transmission, GABAergic", "up-regulation of synaptic transmission, GABAergic", "upregulation of synaptic transmission, GABAergic" ; oboInOwl:hasNarrowSynonym "activation of synaptic transmission, GABAergic", "stimulation of synaptic transmission, GABAergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032230" ; a owl:Class ; rdfs:label "positive regulation of synaptic transmission, GABAergic" ; rdfs:subClassOf obo:GO_0032228, obo:GO_0050806, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051932 ] ) ] . obo:GO_0032231 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles." ; oboInOwl:hasExactSynonym "regulation of actin cable assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of actin filament bundle formation" ; oboInOwl:id "GO:0032231" ; a owl:Class ; rdfs:label "regulation of actin filament bundle assembly" ; rdfs:subClassOf obo:GO_0044087, obo:GO_0110053, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051017 ] ) ] . obo:GO_0032232 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles." ; oboInOwl:hasExactSynonym "down regulation of actin filament bundle formation", "down-regulation of actin filament bundle formation", "downregulation of actin filament bundle formation" ; oboInOwl:hasNarrowSynonym "inhibition of actin filament bundle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032232" ; a owl:Class ; rdfs:label "negative regulation of actin filament bundle assembly" ; rdfs:subClassOf obo:GO_0032231, obo:GO_0051494, obo:GO_1902904, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051017 ] ) ] . obo:GO_0032233 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles." ; oboInOwl:hasExactSynonym "up regulation of actin filament bundle formation", "up-regulation of actin filament bundle formation", "upregulation of actin filament bundle formation" ; oboInOwl:hasNarrowSynonym "activation of actin filament bundle formation", "stimulation of actin filament bundle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032233" ; a owl:Class ; rdfs:label "positive regulation of actin filament bundle assembly" ; rdfs:subClassOf obo:GO_0032231, obo:GO_0044089, obo:GO_0051495, obo:GO_1902905, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051017 ] ) ] . obo:GO_0032239 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:id "GO:0032239" ; a owl:Class ; rdfs:label "regulation of nucleobase-containing compound transport" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015931 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015931 ] ) ] . obo:GO_0032240 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:hasNarrowSynonym "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:id "GO:0032240" ; a owl:Class ; rdfs:label "negative regulation of nucleobase-containing compound transport" ; rdfs:subClassOf obo:GO_0032239, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015931 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015931 ] ) ] . obo:GO_0032241 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:hasNarrowSynonym "activation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:id "GO:0032241" ; a owl:Class ; rdfs:label "positive regulation of nucleobase-containing compound transport" ; rdfs:subClassOf obo:GO_0032239, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015931 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015931 ] ) ] . obo:GO_0032252 obo:IAO_0000115 "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell." ; oboInOwl:hasExactSynonym "secretory granule localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "secretory granule clustering" ; oboInOwl:id "GO:0032252" ; a owl:Class ; rdfs:label "secretory granule localization" ; rdfs:subClassOf obo:GO_0051648, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0030141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0030141 ] ) ] . obo:GO_0032259 obo:IAO_0000115 "The process in which a methyl group is covalently attached to a molecule." ; oboInOwl:hasDbXref "Wikipedia:Methylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032259" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "methylation" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0032271 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." ; oboInOwl:hasExactSynonym "regulation of protein polymerisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032271" ; a owl:Class ; rdfs:label "regulation of protein polymerization" ; rdfs:subClassOf obo:GO_0043254, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051258 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051258 ] ) ] . obo:GO_0032272 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." ; oboInOwl:hasExactSynonym "down regulation of protein polymerization", "down-regulation of protein polymerization", "downregulation of protein polymerization" ; oboInOwl:hasNarrowSynonym "inhibition of protein polymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032272" ; a owl:Class ; rdfs:label "negative regulation of protein polymerization" ; rdfs:subClassOf obo:GO_0031333, obo:GO_0032271, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051258 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051258 ] ) ] . obo:GO_0032273 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." ; oboInOwl:hasExactSynonym "up regulation of protein polymerization", "up-regulation of protein polymerization", "upregulation of protein polymerization" ; oboInOwl:hasNarrowSynonym "activation of protein polymerization", "stimulation of protein polymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032273" ; a owl:Class ; rdfs:label "positive regulation of protein polymerization" ; rdfs:subClassOf obo:GO_0031334, obo:GO_0032271, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051258 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051258 ] ) ] . obo:GO_0032297 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication." ; oboInOwl:hasBroadSynonym "negative regulation of DNA replication initiation" ; oboInOwl:hasExactSynonym "down regulation of DNA replication initiation", "down-regulation of DNA replication initiation", "downregulation of DNA replication initiation", "negative regulation of DNA-dependent DNA replication initiation" ; oboInOwl:hasNarrowSynonym "inhibition of DNA replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032297" ; a owl:Class ; rdfs:label "negative regulation of DNA-templated DNA replication initiation" ; rdfs:subClassOf obo:GO_0030174, obo:GO_2000104, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006270 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006270 ] ) ] . obo:GO_0032298 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication." ; oboInOwl:hasBroadSynonym "negative regulation of DNA replication initiation" ; oboInOwl:hasExactSynonym "positive regulation of DNA-dependent DNA replication initiation", "up regulation of DNA replication initiation", "up-regulation of DNA replication initiation", "upregulation of DNA replication initiation" ; oboInOwl:hasNarrowSynonym "activation of DNA replication initiation", "stimulation of DNA replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032298" ; a owl:Class ; rdfs:label "positive regulation of DNA-templated DNA replication initiation" ; rdfs:subClassOf obo:GO_0030174, obo:GO_2000105, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006270 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006270 ] ) ] . obo:GO_0032330 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of chondrocyte differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032330" ; a owl:Class ; rdfs:label "regulation of chondrocyte differentiation" ; rdfs:subClassOf obo:GO_0045595, obo:GO_0061035, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002062 ] ) ] . obo:GO_0032331 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation." ; oboInOwl:hasExactSynonym "down regulation of chondrocyte differentiation", "down-regulation of chondrocyte differentiation", "downregulation of chondrocyte differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of chondrocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032331" ; a owl:Class ; rdfs:label "negative regulation of chondrocyte differentiation" ; rdfs:subClassOf obo:GO_0032330, obo:GO_0045596, obo:GO_0061037, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002062 ] ) ] . obo:GO_0032332 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation." ; oboInOwl:hasExactSynonym "up regulation of chondrocyte differentiation", "up-regulation of chondrocyte differentiation", "upregulation of chondrocyte differentiation" ; oboInOwl:hasNarrowSynonym "activation of chondrocyte differentiation", "stimulation of chondrocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032332" ; a owl:Class ; rdfs:label "positive regulation of chondrocyte differentiation" ; rdfs:subClassOf obo:GO_0032330, obo:GO_0045597, obo:GO_0061036, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002062 ] ) ] . obo:GO_0032350 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ; oboInOwl:hasExactSynonym "regulation of hormone metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032350" ; a owl:Class ; rdfs:label "regulation of hormone metabolic process" ; rdfs:subClassOf obo:GO_0010817, obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042445 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042445 ] ) ] . obo:GO_0032351 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ; oboInOwl:hasExactSynonym "down regulation of hormone metabolic process", "down-regulation of hormone metabolic process", "downregulation of hormone metabolic process", "negative regulation of hormone metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of hormone metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032351" ; a owl:Class ; rdfs:label "negative regulation of hormone metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0032350, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042445 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042445 ] ) ] . obo:GO_0032352 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ; oboInOwl:hasExactSynonym "positive regulation of hormone metabolism", "up regulation of hormone metabolic process", "up-regulation of hormone metabolic process", "upregulation of hormone metabolic process" ; oboInOwl:hasNarrowSynonym "activation of hormone metabolic process", "stimulation of hormone metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032352" ; a owl:Class ; rdfs:label "positive regulation of hormone metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0032350, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042445 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042445 ] ) ] . obo:GO_0032364 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24224"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "oxygen homeostasis" ; oboInOwl:hasExactSynonym "cellular oxygen homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032364" ; a owl:Class ; rdfs:label "intracellular oxygen homeostasis" ; rdfs:subClassOf obo:GO_0055082, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_15379 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055082 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_15379 ] ) ] . obo:GO_0032365 obo:IAO_0000115 "The directed movement of lipids within cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032365" ; a owl:Class ; rdfs:label "intracellular lipid transport" ; rdfs:subClassOf obo:GO_0006869, obo:GO_0046907 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0032368 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032368" ; a owl:Class ; rdfs:label "regulation of lipid transport" ; rdfs:subClassOf obo:GO_0051049, obo:GO_1905952, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006869 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006869 ] ) ] . obo:GO_0032369 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of lipid transport", "down-regulation of lipid transport", "downregulation of lipid transport" ; oboInOwl:hasNarrowSynonym "inhibition of lipid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032369" ; a owl:Class ; rdfs:label "negative regulation of lipid transport" ; rdfs:subClassOf obo:GO_0032368, obo:GO_0051051, obo:GO_1905953, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006869 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006869 ] ) ] . obo:GO_0032370 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of lipid transport", "up-regulation of lipid transport", "upregulation of lipid transport" ; oboInOwl:hasNarrowSynonym "activation of lipid transport", "stimulation of lipid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032370" ; a owl:Class ; rdfs:label "positive regulation of lipid transport" ; rdfs:subClassOf obo:GO_0032368, obo:GO_0051050, obo:GO_1905954, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006869 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006869 ] ) ] . obo:GO_0032377 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032377" ; a owl:Class ; rdfs:label "regulation of intracellular lipid transport" ; rdfs:subClassOf obo:GO_0032368, obo:GO_0032386, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032365 ] ) ] . obo:GO_0032378 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells." ; oboInOwl:hasExactSynonym "down regulation of intracellular lipid transport", "down-regulation of intracellular lipid transport", "downregulation of intracellular lipid transport" ; oboInOwl:hasNarrowSynonym "inhibition of intracellular lipid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032378" ; a owl:Class ; rdfs:label "negative regulation of intracellular lipid transport" ; rdfs:subClassOf obo:GO_0032369, obo:GO_0032377, obo:GO_0032387, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032365 ] ) ] . obo:GO_0032379 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells." ; oboInOwl:hasExactSynonym "up regulation of intracellular lipid transport", "up-regulation of intracellular lipid transport", "upregulation of intracellular lipid transport" ; oboInOwl:hasNarrowSynonym "activation of intracellular lipid transport", "stimulation of intracellular lipid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032379" ; a owl:Class ; rdfs:label "positive regulation of intracellular lipid transport" ; rdfs:subClassOf obo:GO_0032370, obo:GO_0032377, obo:GO_0032388, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032365 ] ) ] . obo:GO_0032386 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032386" ; a owl:Class ; rdfs:label "regulation of intracellular transport" ; rdfs:subClassOf obo:GO_0051049, obo:GO_0060341, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046907 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046907 ] ) ] . obo:GO_0032387 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." ; oboInOwl:hasExactSynonym "down regulation of intracellular transport", "down-regulation of intracellular transport", "downregulation of intracellular transport" ; oboInOwl:hasNarrowSynonym "inhibition of intracellular transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032387" ; a owl:Class ; rdfs:label "negative regulation of intracellular transport" ; rdfs:subClassOf obo:GO_0032386, obo:GO_0048523, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046907 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046907 ] ) ] . obo:GO_0032388 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." ; oboInOwl:hasExactSynonym "up regulation of intracellular transport", "up-regulation of intracellular transport", "upregulation of intracellular transport" ; oboInOwl:hasNarrowSynonym "activation of intracellular transport", "stimulation of intracellular transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032388" ; a owl:Class ; rdfs:label "positive regulation of intracellular transport" ; rdfs:subClassOf obo:GO_0032386, obo:GO_0048522, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046907 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046907 ] ) ] . obo:GO_0032409 obo:IAO_0000115 "Any process that modulates the activity of a transporter." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032409" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of transporter activity" ; rdfs:subClassOf obo:GO_0065009, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005215 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005215 ] ) ] . obo:GO_0032410 obo:IAO_0000115 "Any process that stops or reduces the activity of a transporter." ; oboInOwl:hasExactSynonym "down regulation of transporter activity", "down-regulation of transporter activity", "downregulation of transporter activity" ; oboInOwl:hasNarrowSynonym "inhibition of transporter activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032410" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of transporter activity" ; rdfs:subClassOf obo:GO_0032409, obo:GO_0044092, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005215 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005215 ] ) ] . obo:GO_0032411 obo:IAO_0000115 "Any process that activates or increases the activity of a transporter." ; oboInOwl:hasExactSynonym "up regulation of transporter activity", "up-regulation of transporter activity", "upregulation of transporter activity" ; oboInOwl:hasNarrowSynonym "activation of transporter activity", "stimulation of transporter activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032411" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of transporter activity" ; rdfs:subClassOf obo:GO_0032409, obo:GO_0044093, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005215 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005215 ] ) ] . obo:GO_0032412 obo:IAO_0000115 "Any process that modulates the activity of an ion transporter." ; oboInOwl:hasBroadSynonym "regulation of ion transmembrane transporter activity" ; oboInOwl:hasExactSynonym "regulation of ion transporter activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032412" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of monoatomic ion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022898, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015075 ] ) ] . obo:GO_0032413 obo:IAO_0000115 "Any process that stops or reduces the activity of an ion transporter." ; oboInOwl:hasExactSynonym "down regulation of ion transporter activity", "down-regulation of ion transporter activity", "downregulation of ion transporter activity", "negative regulation of ion transporter activity" ; oboInOwl:hasNarrowSynonym "inhibition of ion transporter activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032413" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of ion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0032410, obo:GO_0032412, obo:GO_0034766, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015075 ] ) ] . obo:GO_0032414 obo:IAO_0000115 "Any process that activates or increases the activity of an ion transporter." ; oboInOwl:hasExactSynonym "positive regulation of ion transporter activity", "up regulation of ion transporter activity", "up-regulation of ion transporter activity", "upregulation of ion transporter activity" ; oboInOwl:hasNarrowSynonym "activation of ion transporter activity", "stimulation of ion transporter activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032414" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of ion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0032411, obo:GO_0032412, obo:GO_0034767, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015075 ] ) ] . obo:GO_0032418 obo:IAO_0000115 "Any process in which a lysosome is transported to, and/or maintained in, a specific location." ; oboInOwl:hasExactSynonym "lysosome localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032418" ; a owl:Class ; rdfs:label "lysosome localization" ; rdfs:subClassOf obo:GO_1990849, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005764 ] ) ] . obo:GO_0032432 obo:IAO_0000115 "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." ; oboInOwl:hasAlternativeId "GO:0000141", "GO:0030482" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "actin cable" ; oboInOwl:id "GO:0032432" ; a owl:Class ; rdfs:label "actin filament bundle" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015629 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005884 ] . obo:GO_0032459 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein oligomerization." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032459" ; a owl:Class ; rdfs:label "regulation of protein oligomerization" ; rdfs:subClassOf obo:GO_0043254, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051259 ] ) ] . obo:GO_0032460 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization." ; oboInOwl:hasExactSynonym "down regulation of protein oligomerization", "down-regulation of protein oligomerization", "downregulation of protein oligomerization" ; oboInOwl:hasNarrowSynonym "inhibition of protein oligomerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032460" ; a owl:Class ; rdfs:label "negative regulation of protein oligomerization" ; rdfs:subClassOf obo:GO_0031333, obo:GO_0032459, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051259 ] ) ] . obo:GO_0032461 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein oligomerization." ; oboInOwl:hasExactSynonym "up regulation of protein oligomerization", "up-regulation of protein oligomerization", "upregulation of protein oligomerization" ; oboInOwl:hasNarrowSynonym "activation of protein oligomerization", "stimulation of protein oligomerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "induction of protein oligomerization" ; oboInOwl:id "GO:0032461" ; a owl:Class ; rdfs:label "positive regulation of protein oligomerization" ; rdfs:subClassOf obo:GO_0031334, obo:GO_0032459, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051259 ] ) ] . obo:GO_0032465 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells." ; oboInOwl:hasAlternativeId "GO:0071775" ; oboInOwl:hasExactSynonym "regulation of cell cycle cytokinesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032465" ; a owl:Class ; rdfs:label "regulation of cytokinesis" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0051302, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000910 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000910 ] ) ] . obo:GO_0032466 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." ; oboInOwl:hasAlternativeId "GO:0071776" ; oboInOwl:hasExactSynonym "down regulation of cytokinesis", "down-regulation of cytokinesis", "downregulation of cytokinesis" ; oboInOwl:hasNarrowSynonym "inhibition of cytokinesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell cycle cytokinesis" ; oboInOwl:id "GO:0032466" ; a owl:Class ; rdfs:label "negative regulation of cytokinesis" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0032465, obo:GO_0051782, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000910 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000910 ] ) ] . obo:GO_0032467 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." ; oboInOwl:hasAlternativeId "GO:0071777" ; oboInOwl:hasExactSynonym "up regulation of cytokinesis", "up-regulation of cytokinesis", "upregulation of cytokinesis" ; oboInOwl:hasNarrowSynonym "activation of cytokinesis", "stimulation of cytokinesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cell cycle cytokinesis" ; oboInOwl:id "GO:0032467" ; a owl:Class ; rdfs:label "positive regulation of cytokinesis" ; rdfs:subClassOf obo:GO_0032465, obo:GO_0051781, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000910 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000910 ] ) ] . obo:GO_0032468 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings." ; oboInOwl:hasExactSynonym "Golgi calcium ion concentration regulation", "calcium ion homeostasis in Golgi", "regulation of Golgi calcium ion concentration", "regulation of calcium ion concentration in Golgi" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032468" ; a owl:Class ; rdfs:label "Golgi calcium ion homeostasis" ; rdfs:subClassOf obo:GO_0006874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005794 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055074 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005794 ] ) ] . obo:GO_0032472 obo:IAO_0000115 "The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus." ; oboInOwl:hasExactSynonym "Golgi calcium transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032472" ; a owl:Class ; rdfs:label "Golgi calcium ion transport" ; rdfs:subClassOf obo:GO_0006816, [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29108 ] ) ] . obo:GO_0032501 obo:IAO_0000115 "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." ; obo:RO_0002161 obo:NCBITaxon_2, obo:NCBITaxon_2157, obo:NCBITaxon_4896, obo:NCBITaxon_4932 ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T16:07:47Z" ; oboInOwl:hasAlternativeId "GO:0044707", "GO:0050874" ; oboInOwl:hasExactSynonym "organismal physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-multicellular organism process" ; oboInOwl:id "GO:0032501" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:label "multicellular organismal process" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_2 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_2157 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4896 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4932 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_2 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_2157 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4896 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4932 ] ] ; owl:disjointWith obo:GO_0044848, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_2 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_2157 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4896 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4932 ] . obo:GO_0032502 obo:IAO_0000115 "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-12-19T12:21:31Z" ; oboInOwl:hasAlternativeId "GO:0044767" ; oboInOwl:hasNarrowSynonym "development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism developmental process" ; oboInOwl:id "GO:0032502" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_pir ; a owl:Class ; rdfs:label "developmental process" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0032504 obo:IAO_0000115 "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032504" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "multicellular organism reproduction" ; rdfs:subClassOf obo:GO_0000003, obo:GO_0032501 . obo:GO_0032507 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "maintenance of protein localization in cell" ; oboInOwl:id "GO:0032507" ; a owl:Class ; rdfs:label "maintenance of protein location in cell" ; rdfs:subClassOf obo:GO_0045185, obo:GO_0051651 . obo:GO_0032528 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasExactSynonym "microvillus organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microvillus organization and biogenesis" ; oboInOwl:id "GO:0032528" ; a owl:Class ; rdfs:label "microvillus organization" ; rdfs:subClassOf obo:GO_0120036, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005902 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005902 ] ) ] . obo:GO_0032530 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus." ; oboInOwl:hasExactSynonym "regulation of microvillus organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of microvillus organization and biogenesis" ; oboInOwl:id "GO:0032530" ; a owl:Class ; rdfs:label "regulation of microvillus organization" ; rdfs:subClassOf obo:GO_0120035, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032528 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032528 ] ) ] . obo:GO_0032534 obo:IAO_0000115 "A process that modulates the formation of a microvillus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of microvillus biogenesis" ; oboInOwl:id "GO:0032534" ; a owl:Class ; rdfs:label "regulation of microvillus assembly" ; rdfs:subClassOf obo:GO_0032530, obo:GO_0120032, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030033 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030033 ] ) ] . obo:GO_0032535 obo:IAO_0000115 "A process that modulates the size of a cellular component." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032535" ; a owl:Class ; rdfs:label "regulation of cellular component size" ; rdfs:subClassOf obo:GO_0016043, obo:GO_0090066 . obo:GO_0032543 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code." ; oboInOwl:hasExactSynonym "mitochondrial protein anabolism", "mitochondrial protein biosynthesis", "mitochondrial protein formation", "mitochondrial protein synthesis", "mitochondrial protein translation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032543" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "mitochondrial translation" ; rdfs:subClassOf obo:GO_0006412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140053 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006412 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140053 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0032589 obo:IAO_0000115 "The portion of the plasma membrane surrounding a neuron projection." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032589" ; a owl:Class ; rdfs:label "neuron projection membrane" ; rdfs:subClassOf obo:GO_0031253, obo:GO_0031256, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043005 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0043005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0043005 ] ) ] . obo:GO_0032590 obo:IAO_0000115 "The portion of the plasma membrane surrounding a dendrite." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032590" ; a owl:Class ; rdfs:label "dendrite membrane" ; rdfs:subClassOf obo:GO_0032589, [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0030425 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0030425 ] ) ] . obo:GO_0032594 obo:IAO_0000115 "The directed movement of a protein from one location to another within a lipid bilayer." ; oboInOwl:hasExactSynonym "protein translocation within membrane" ; oboInOwl:hasNarrowSynonym "receptor translocation within membrane", "receptor transport within lipid bilayer" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032594" ; a owl:Class ; rdfs:label "protein transport within lipid bilayer" ; rdfs:subClassOf obo:GO_0006886, obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0015031 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0032774 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." ; oboInOwl:hasAlternativeId "GO:0062103" ; oboInOwl:hasExactSynonym "RNA anabolism", "RNA biosynthesis", "RNA formation", "RNA synthesis" ; oboInOwl:hasNarrowSynonym "double-stranded RNA biosynthesis", "double-stranded RNA biosynthetic process", "dsRNA biosynthesis", "dsRNA biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032774" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study." ; rdfs:label "RNA biosynthetic process" ; rdfs:subClassOf obo:GO_0009059, obo:GO_0016070, obo:GO_0034654, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33697 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33697 ] ) ] . obo:GO_0032782 obo:IAO_0000115 "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032782" ; a owl:Class ; rdfs:label "bile acid secretion" ; rdfs:subClassOf obo:GO_0015718, obo:GO_0046717, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36235 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36235 ] ) ] . obo:GO_0032787 obo:IAO_0000115 "The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-)." ; oboInOwl:hasExactSynonym "monocarboxylate metabolic process", "monocarboxylic acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032787" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "monocarboxylic acid metabolic process" ; rdfs:subClassOf obo:GO_0019752, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35757 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35757 ] ) ] . obo:GO_0032790 obo:IAO_0000115 "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits." ; oboInOwl:hasNarrowSynonym "ribosome recycling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ribosome dissociation factor" ; oboInOwl:id "GO:0032790" ; a owl:Class ; rdfs:label "ribosome disassembly" ; rdfs:subClassOf obo:GO_1903008, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005840 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005840 ] ) ] . obo:GO_0032838 obo:IAO_0000115 "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032838" ; a owl:Class ; rdfs:label "plasma membrane bounded cell projection cytoplasm" ; rdfs:subClassOf obo:GO_0099568, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0120025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0120025 ] ) ] . obo:GO_0032839 obo:IAO_0000115 "All of the contents of a dendrite, excluding the surrounding plasma membrane." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI ; oboInOwl:hasExactSynonym "dendritic cytoplasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032839" ; a owl:Class ; rdfs:label "dendrite cytoplasm" ; rdfs:subClassOf obo:GO_0120111, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030425 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030425 ] ) ] . obo:GO_0032847 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell." ; oboInOwl:hasExactSynonym "regulation of cell pH reduction", "regulation of cellular acidification", "regulation of intracellular pH reduction", "regulation of reduction of cellular pH", "regulation of reduction of pH in cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of intracellular acidification" ; oboInOwl:id "GO:0032847" ; a owl:Class ; rdfs:label "regulation of cellular pH reduction" ; rdfs:subClassOf obo:GO_0050789, obo:GO_0051453, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051452 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051452 ] ) ] . obo:GO_0032848 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell." ; oboInOwl:hasExactSynonym "down regulation of cellular pH reduction", "down-regulation of cellular pH reduction", "downregulation of cellular pH reduction", "negative regulation of cell pH reduction", "negative regulation of cellular acidification", "negative regulation of intracellular pH reduction", "negative regulation of reduction of cellular pH", "negative regulation of reduction of pH in cell" ; oboInOwl:hasNarrowSynonym "inhibition of cellular pH reduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of intracellular acidification" ; oboInOwl:id "GO:0032848" ; a owl:Class ; rdfs:label "negative regulation of cellular pH reduction" ; rdfs:subClassOf obo:GO_0032847, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051452 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051452 ] ) ] . obo:GO_0032849 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell." ; oboInOwl:hasExactSynonym "positive regulation of cell pH reduction", "positive regulation of cellular acidification", "positive regulation of intracellular pH reduction", "positive regulation of reduction of cellular pH", "positive regulation of reduction of pH in cell", "up regulation of cellular pH reduction", "up-regulation of cellular pH reduction", "upregulation of cellular pH reduction" ; oboInOwl:hasNarrowSynonym "activation of cellular pH reduction", "stimulation of cellular pH reduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of intracellular acidification" ; oboInOwl:id "GO:0032849" ; a owl:Class ; rdfs:label "positive regulation of cellular pH reduction" ; rdfs:subClassOf obo:GO_0032847, obo:GO_0048518, obo:GO_0051452, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051452 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051452 ] ) ] . obo:GO_0032868 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." ; oboInOwl:hasExactSynonym "response to insulin stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032868" ; a owl:Class ; rdfs:label "response to insulin" ; rdfs:subClassOf obo:GO_0043434, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000009054 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042221 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000009054 ] ) ] . obo:GO_0032869 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032869" ; a owl:Class ; rdfs:label "cellular response to insulin stimulus" ; rdfs:subClassOf obo:GO_0032868, obo:GO_0071375 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000009054 ] ) ] . obo:GO_0032871 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032871" ; a owl:Class ; rdfs:label "regulation of karyogamy" ; rdfs:subClassOf obo:GO_1903353, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000741 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000741 ] ) ] . obo:GO_0032875 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of DNA endoreduplication." ; oboInOwl:hasExactSynonym "regulation of DNA endoreplication", "regulation of DNA re-duplication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032875" ; a owl:Class ; rdfs:label "regulation of DNA endoreduplication" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0090329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042023 ] ) ] . obo:GO_0032876 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication." ; oboInOwl:hasExactSynonym "down regulation of DNA endoreduplication", "down-regulation of DNA endoreduplication", "downregulation of DNA endoreduplication", "negative regulation of DNA endoreplication", "negative regulation of DNA re-duplication" ; oboInOwl:hasNarrowSynonym "inhibition of DNA endoreduplication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032876" ; a owl:Class ; rdfs:label "negative regulation of DNA endoreduplication" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0032875, obo:GO_2000104, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042023 ] ) ] . obo:GO_0032877 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of DNA endoreduplication." ; oboInOwl:hasExactSynonym "positive regulation of DNA endoreplication", "positive regulation of DNA re-duplication", "up regulation of DNA endoreduplication", "up-regulation of DNA endoreduplication", "upregulation of DNA endoreduplication" ; oboInOwl:hasNarrowSynonym "activation of DNA endoreduplication", "stimulation of DNA endoreduplication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032877" ; a owl:Class ; rdfs:label "positive regulation of DNA endoreduplication" ; rdfs:subClassOf obo:GO_0032875, obo:GO_0090068, obo:GO_2000105, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042023 ] ) ] . obo:GO_0032878 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032878" ; a owl:Class ; rdfs:label "regulation of establishment or maintenance of cell polarity" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007163 ] ) ] . obo:GO_0032879 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "regulation of localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032879" ; a owl:Class ; rdfs:label "regulation of localization" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051179 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051179 ] ) ] . obo:GO_0032880 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2015-01-20T14:32:14Z" ; oboInOwl:hasAlternativeId "GO:1903827" ; oboInOwl:hasExactSynonym "regulation of cellular protein localisation", "regulation of cellular protein localization", "regulation of protein localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032880" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "regulation of protein localization" ; rdfs:subClassOf obo:GO_0060341, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008104 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008104 ] ) ] . obo:GO_0032881 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032881" ; a owl:Class ; rdfs:label "regulation of polysaccharide metabolic process" ; rdfs:subClassOf obo:GO_0006109, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005976 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005976 ] ) ] . obo:GO_0032885 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032885" ; a owl:Class ; rdfs:label "regulation of polysaccharide biosynthetic process" ; rdfs:subClassOf obo:GO_0010556, obo:GO_0032881, obo:GO_0043255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000271 ] ) ] . obo:GO_0032886 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032886" ; a owl:Class ; rdfs:label "regulation of microtubule-based process" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007017 ] ) ] . obo:GO_0032887 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032887" ; a owl:Class ; rdfs:label "regulation of spindle elongation" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0032886, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051231 ] ) ] . obo:GO_0032888 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032888" ; a owl:Class ; rdfs:label "regulation of mitotic spindle elongation" ; rdfs:subClassOf obo:GO_0032887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033047 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000022 ] ) ] . obo:GO_0032890 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032890" ; a owl:Class ; rdfs:label "regulation of organic acid transport" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015849 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015849 ] ) ] . obo:GO_0032891 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of organic acid transport", "down-regulation of organic acid transport", "downregulation of organic acid transport" ; oboInOwl:hasNarrowSynonym "inhibition of organic acid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032891" ; a owl:Class ; rdfs:label "negative regulation of organic acid transport" ; rdfs:subClassOf obo:GO_0032890, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015849 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015849 ] ) ] . obo:GO_0032892 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of organic acid transport", "up-regulation of organic acid transport", "upregulation of organic acid transport" ; oboInOwl:hasNarrowSynonym "activation of organic acid transport", "stimulation of organic acid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032892" ; a owl:Class ; rdfs:label "positive regulation of organic acid transport" ; rdfs:subClassOf obo:GO_0032890, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015849 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015849 ] ) ] . obo:GO_0032939 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ; oboInOwl:hasExactSynonym "up regulation of translation in response to oxidative stress", "up-regulation of translation in response to oxidative stress", "upregulation of translation in response to oxidative stress" ; oboInOwl:hasNarrowSynonym "activation of translation in response to oxidative stress", "stimulation of translation in response to oxidative stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032939" ; a owl:Class ; rdfs:label "positive regulation of translation in response to oxidative stress" ; rdfs:subClassOf obo:GO_0032056, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034599 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032940 obo:IAO_0000115 "The controlled release of a substance by a cell." ; oboInOwl:hasDbXref "Wikipedia:Secretion" ; oboInOwl:hasExactSynonym "cellular secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032940" ; a owl:Class ; rdfs:label "secretion by cell" ; rdfs:subClassOf obo:GO_0046903, obo:GO_0140352 . obo:GO_0032941 obo:IAO_0000115 "The controlled release of a substance by a tissue." ; oboInOwl:hasExactSynonym "tissue secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "expulsion of gland contents" ; oboInOwl:id "GO:0032941" ; a owl:Class ; rdfs:label "secretion by tissue" ; rdfs:subClassOf obo:GO_0032501, obo:GO_0046903 . obo:GO_0032943 obo:IAO_0000115 "The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form." ; oboInOwl:hasNarrowSynonym "PBMC proliferation", "peripheral blood mononuclear cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032943" ; a owl:Class ; rdfs:label "mononuclear cell proliferation" ; rdfs:subClassOf obo:GO_0070661, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000842 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000842 ] ) ] . obo:GO_0032944 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation." ; oboInOwl:hasNarrowSynonym "regulation of PBMC proliferation", "regulation of peripheral blood mononuclear cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032944" ; a owl:Class ; rdfs:label "regulation of mononuclear cell proliferation" ; rdfs:subClassOf obo:GO_0070663, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032943 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032943 ] ) ] . obo:GO_0032945 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation." ; oboInOwl:hasNarrowSynonym "negative regulation of PBMC proliferation", "negative regulation of peripheral blood mononuclear cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032945" ; a owl:Class ; rdfs:label "negative regulation of mononuclear cell proliferation" ; rdfs:subClassOf obo:GO_0032944, obo:GO_0070664, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032943 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032943 ] ) ] . obo:GO_0032946 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation." ; oboInOwl:hasExactSynonym "up regulation of mononuclear cell proliferation", "up-regulation of mononuclear cell proliferation", "upregulation of mononuclear cell proliferation" ; oboInOwl:hasNarrowSynonym "activation of mononuclear cell proliferation", "positive regulation of PBMC proliferation", "positive regulation of peripheral blood mononuclear cell proliferation", "stimulation of mononuclear cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032946" ; a owl:Class ; rdfs:label "positive regulation of mononuclear cell proliferation" ; rdfs:subClassOf obo:GO_0032944, obo:GO_0070665, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032943 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032943 ] ) ] . obo:GO_0032956 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ; oboInOwl:hasExactSynonym "regulation of actin cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of actin cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0032956" ; a owl:Class ; rdfs:label "regulation of actin cytoskeleton organization" ; rdfs:subClassOf obo:GO_0032970, obo:GO_0051493, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030036 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030036 ] ) ] . obo:GO_0032963 obo:IAO_0000115 "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." ; oboInOwl:hasExactSynonym "collagen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032963" ; a owl:Class ; rdfs:label "collagen metabolic process" ; rdfs:subClassOf obo:GO_0008152, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:GO_0005581 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:GO_0005581 ] ) ] . obo:GO_0032964 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%)." ; oboInOwl:hasExactSynonym "collagen anabolism", "collagen biosynthesis", "collagen formation", "collagen synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032964" ; a owl:Class ; rdfs:label "collagen biosynthetic process" ; rdfs:subClassOf obo:GO_0009058, obo:GO_0032963, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:GO_0005581 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:GO_0005581 ] ) ] . obo:GO_0032965 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ; oboInOwl:hasExactSynonym "regulation of collagen anabolism", "regulation of collagen biosynthesis", "regulation of collagen formation", "regulation of collagen synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032965" ; a owl:Class ; rdfs:label "regulation of collagen biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0010712, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032964 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032964 ] ) ] . obo:GO_0032966 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ; oboInOwl:hasExactSynonym "negative regulation of collagen anabolism", "negative regulation of collagen biosynthesis", "negative regulation of collagen formation", "negative regulation of collagen synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032966" ; a owl:Class ; rdfs:label "negative regulation of collagen biosynthetic process" ; rdfs:subClassOf obo:GO_0009890, obo:GO_0010713, obo:GO_0032965, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032964 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032964 ] ) ] . obo:GO_0032967 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals." ; oboInOwl:hasExactSynonym "positive regulation of collagen anabolism", "positive regulation of collagen biosynthesis", "positive regulation of collagen formation", "positive regulation of collagen synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032967" ; a owl:Class ; rdfs:label "positive regulation of collagen biosynthetic process" ; rdfs:subClassOf obo:GO_0009891, obo:GO_0010714, obo:GO_0032965, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032964 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032964 ] ) ] . obo:GO_0032970 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032970" ; a owl:Class ; rdfs:label "regulation of actin filament-based process" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030029 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030029 ] ) ] . obo:GO_0032982 obo:IAO_0000115 "A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "myosin thick filament", "thick filament" ; oboInOwl:id "GO:0032982" ; a owl:Class ; rdfs:label "myosin filament" ; rdfs:subClassOf obo:GO_0099512, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016459 ] . obo:GO_0032984 obo:IAO_0000115 "The disaggregation of a protein-containing macromolecular complex into its constituent components." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22580"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0034623", "GO:0043241", "GO:0043624" ; oboInOwl:hasExactSynonym "protein complex disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular macromolecule complex disassembly", "cellular protein complex disassembly", "macromolecule complex disassembly" ; oboInOwl:id "GO:0032984" ; a owl:Class ; rdfs:label "protein-containing complex disassembly" ; rdfs:subClassOf obo:GO_0022411, obo:GO_0043933, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0032991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0032991 ] ) ] . obo:GO_0032986 obo:IAO_0000115 "The disaggregation of a protein-DNA complex into its constituent components." ; oboInOwl:hasExactSynonym "DNA-protein complex disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032986" ; a owl:Class ; rdfs:label "protein-DNA complex disassembly" ; rdfs:subClassOf obo:GO_0032984, obo:GO_0071824, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0032993 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0032993 ] ) ] . obo:GO_0032988 obo:IAO_0000115 "The disaggregation of a protein-RNA complex into its constituent components." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25143"^^xsd:anyURI ; oboInOwl:hasExactSynonym "RNA-protein complex disassembly", "RNP complex disassembly", "ribonucleoprotein complex disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032988" ; a owl:Class ; rdfs:label "protein-RNA complex disassembly" ; rdfs:subClassOf obo:GO_0032984, obo:GO_0071826, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_1990904 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_1990904 ] ) ] . obo:GO_0032989 obo:IAO_0000115 "The process in which cellular structures, including whole cells or cell parts, are generated and organized." ; oboInOwl:hasExactSynonym "cellular structure morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032989" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular component morphogenesis" ; rdfs:subClassOf obo:GO_0009653, obo:GO_0016043, obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0005575 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0005575 ] ) ] . obo:GO_0032990 obo:IAO_0000115 "The process in which the anatomical structures of a cell part are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032990" ; a owl:Class ; rdfs:label "cell part morphogenesis" ; rdfs:subClassOf obo:GO_0032989, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0110165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0110165 ] ) ] . obo:GO_0032991 obo:IAO_0000115 "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ; oboInOwl:hasAlternativeId "GO:0043234" ; oboInOwl:hasExactSynonym "macromolecular complex", "macromolecule complex", "protein containing complex" ; oboInOwl:hasNarrowSynonym "protein complex", "protein-protein complex" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032991" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir ; a owl:Class ; rdfs:comment "A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole." ; rdfs:label "protein-containing complex" ; rdfs:subClassOf obo:GO_0005575, obo:PR_000050567 ; owl:disjointWith obo:GO_0110165 . obo:GO_0032993 obo:IAO_0000115 "A macromolecular complex containing both protein and DNA molecules." ; oboInOwl:hasExactSynonym "DNA-protein complex" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032993" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here." ; rdfs:label "protein-DNA complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16991 ] . obo:GO_0033002 obo:IAO_0000115 "The expansion of a muscle cell population by cell division." ; oboInOwl:hasExactSynonym "myocyte proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033002" ; a owl:Class ; rdfs:label "muscle cell proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000187 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:GO_0033013 obo:IAO_0000115 "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." ; oboInOwl:hasExactSynonym "tetrapyrrole metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033013" ; oboInOwl:inSubset go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "tetrapyrrole metabolic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_0046483, obo:GO_1901360, obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_26932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_26932 ] ) ] . obo:GO_0033014 obo:IAO_0000115 "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." ; oboInOwl:hasExactSynonym "tetrapyrrole anabolism", "tetrapyrrole biosynthesis", "tetrapyrrole formation", "tetrapyrrole synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033014" ; a owl:Class ; rdfs:label "tetrapyrrole biosynthetic process" ; rdfs:subClassOf obo:GO_0018130, obo:GO_0019438, obo:GO_0033013, obo:GO_0044271, obo:GO_1901362, obo:GO_1901566, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_26932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_26932 ] ) ] . obo:GO_0033015 obo:IAO_0000115 "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." ; oboInOwl:hasExactSynonym "tetrapyrrole breakdown", "tetrapyrrole catabolism", "tetrapyrrole degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033015" ; a owl:Class ; rdfs:label "tetrapyrrole catabolic process" ; rdfs:subClassOf obo:GO_0019439, obo:GO_0033013, obo:GO_0044270, obo:GO_0046700, obo:GO_1901361, obo:GO_1901565, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_26932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_26932 ] ) ] . obo:GO_0033028 obo:IAO_0000115 "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage." ; oboInOwl:hasExactSynonym "apoptosis of myeloid cells" ; oboInOwl:hasNarrowSynonym "myeloid cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033028" ; a owl:Class ; rdfs:label "myeloid cell apoptotic process" ; rdfs:subClassOf obo:GO_0006915, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000763 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000763 ] ) ] . obo:GO_0033032 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process." ; oboInOwl:hasNarrowSynonym "regulation of myeloid cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033032" ; a owl:Class ; rdfs:label "regulation of myeloid cell apoptotic process" ; rdfs:subClassOf obo:GO_0042981, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033028 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033028 ] ) ] . obo:GO_0033033 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process." ; oboInOwl:hasExactSynonym "down regulation of myeloid cell apoptosis", "down-regulation of myeloid cell apoptosis", "downregulation of myeloid cell apoptosis" ; oboInOwl:hasNarrowSynonym "inhibition of myeloid cell apoptosis", "negative regulation of myeloid cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033033" ; a owl:Class ; rdfs:label "negative regulation of myeloid cell apoptotic process" ; rdfs:subClassOf obo:GO_0033032, obo:GO_0043066, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0033028 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0033028 ] ) ] . obo:GO_0033034 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process." ; oboInOwl:hasExactSynonym "up regulation of myeloid cell apoptosis", "up-regulation of myeloid cell apoptosis", "upregulation of myeloid cell apoptosis" ; oboInOwl:hasNarrowSynonym "activation of myeloid cell apoptosis", "positive regulation of myeloid cell apoptosis", "stimulation of myeloid cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033034" ; a owl:Class ; rdfs:label "positive regulation of myeloid cell apoptotic process" ; rdfs:subClassOf obo:GO_0033032, obo:GO_0043065, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0033028 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0033028 ] ) ] . obo:GO_0033036 obo:IAO_0000115 "Any process in which a macromolecule is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "macromolecule localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033036" ; oboInOwl:inSubset go:goslim_flybase_ribbon ; a owl:Class ; rdfs:label "macromolecule localization" ; rdfs:subClassOf obo:GO_0051179 . obo:GO_0033037 obo:IAO_0000115 "Any process in which a polysaccharide is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "polysaccharide localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033037" ; a owl:Class ; rdfs:label "polysaccharide localization" ; rdfs:subClassOf obo:GO_0033036, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0033036 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18154 ] ) ] . obo:GO_0033043 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ; oboInOwl:hasExactSynonym "regulation of organelle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of organelle organization and biogenesis" ; oboInOwl:id "GO:0033043" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of organelle organization" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006996 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006996 ] ) ] . obo:GO_0033044 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." ; oboInOwl:hasExactSynonym "regulation of chromosome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of chromosome organization and biogenesis" ; oboInOwl:id "GO:0033044" ; a owl:Class ; rdfs:label "regulation of chromosome organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051276 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051276 ] ) ] . obo:GO_0033045 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of sister chromatid segregation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033045" ; a owl:Class ; rdfs:label "regulation of sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033044, obo:GO_0051983, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000819 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000819 ] ) ] . obo:GO_0033046 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033046" ; a owl:Class ; rdfs:label "negative regulation of sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033045, obo:GO_0051985, obo:GO_2001251, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000819 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000819 ] ) ] . obo:GO_0033047 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033047" ; a owl:Class ; rdfs:label "regulation of mitotic sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033045, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000070 ] ) ] . obo:GO_0033048 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033048" ; a owl:Class ; rdfs:label "negative regulation of mitotic sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033046, obo:GO_0033047, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000070 ] ) ] . obo:GO_0033058 obo:IAO_0000115 "Self-propelled movement of a cell or organism from one location to another along an axis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033058" ; a owl:Class ; rdfs:label "directional locomotion" ; rdfs:subClassOf obo:GO_0040011 . obo:GO_0033059 obo:IAO_0000115 "The deposition or aggregation of coloring matter in a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033059" ; a owl:Class ; rdfs:label "cellular pigmentation" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0043473 . obo:GO_0033119 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033119" ; a owl:Class ; rdfs:label "negative regulation of RNA splicing" ; rdfs:subClassOf obo:GO_0010629, obo:GO_0043484, obo:GO_0051253, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008380 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008380 ] ) ] . obo:GO_0033120 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of RNA splicing." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033120" ; a owl:Class ; rdfs:label "positive regulation of RNA splicing" ; rdfs:subClassOf obo:GO_0010628, obo:GO_0043484, obo:GO_0051254, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008380 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008380 ] ) ] . obo:GO_0033157 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033157" ; a owl:Class ; rdfs:label "regulation of intracellular protein transport" ; rdfs:subClassOf obo:GO_0032386, obo:GO_0051223, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006886 ] ) ] . obo:GO_0033206 obo:IAO_0000115 "A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells." ; oboInOwl:hasExactSynonym "cytokinesis after meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033206" ; a owl:Class ; rdfs:label "meiotic cytokinesis" ; rdfs:subClassOf obo:GO_0061640, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061640 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0033218 obo:IAO_0000115 "Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0033218" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "amide binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_32988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_32988 ] ) ] . obo:GO_0033238 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." ; oboInOwl:hasExactSynonym "regulation of amine metabolism", "regulation of cellular amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033238" ; a owl:Class ; rdfs:label "regulation of amine metabolic process" ; rdfs:subClassOf obo:GO_0051171, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009308 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009308 ] ) ] . obo:GO_0033239 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." ; oboInOwl:hasExactSynonym "negative regulation of amine metabolism", "negative regulation of cellular amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033239" ; a owl:Class ; rdfs:label "negative regulation of amine metabolic process" ; rdfs:subClassOf obo:GO_0033238, obo:GO_0051172, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009308 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009308 ] ) ] . obo:GO_0033240 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." ; oboInOwl:hasExactSynonym "positive regulation of amine metabolism", "positive regulation of cellular amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033240" ; a owl:Class ; rdfs:label "positive regulation of amine metabolic process" ; rdfs:subClassOf obo:GO_0033238, obo:GO_0051173, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009308 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009308 ] ) ] . obo:GO_0033241 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ; oboInOwl:hasExactSynonym "regulation of amine breakdown", "regulation of amine catabolism", "regulation of amine degradation", "regulation of cellular amine catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033241" ; a owl:Class ; rdfs:label "regulation of amine catabolic process" ; rdfs:subClassOf obo:GO_0009894, obo:GO_0033238, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009310 ] ) ] . obo:GO_0033242 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ; oboInOwl:hasExactSynonym "negative regulation of amine breakdown", "negative regulation of amine catabolism", "negative regulation of amine degradation", "negative regulation of cellular amine catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033242" ; a owl:Class ; rdfs:label "negative regulation of amine catabolic process" ; rdfs:subClassOf obo:GO_0009895, obo:GO_0033239, obo:GO_0033241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009310 ] ) ] . obo:GO_0033243 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ; oboInOwl:hasExactSynonym "positive regulation of amine breakdown", "positive regulation of amine catabolism", "positive regulation of amine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033243" ; a owl:Class ; rdfs:label "positive regulation of amine catabolic process" ; rdfs:subClassOf obo:GO_0009896, obo:GO_0033240, obo:GO_0033241, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009310 ] ) ] . obo:GO_0033260 obo:IAO_0000115 "The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." ; oboInOwl:hasExactSynonym "DNA replication involved in S phase", "DNA replication involved in S-phase", "nuclear cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA replication during S phase" ; oboInOwl:id "GO:0033260" ; a owl:Class ; rdfs:label "nuclear DNA replication" ; rdfs:subClassOf obo:GO_0044786, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006260 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007049 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0033262 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." ; oboInOwl:hasExactSynonym "regulation of DNA replication involved in S phase", "regulation of DNA replication involved in S-phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of DNA replication during S phase" ; oboInOwl:id "GO:0033262" ; a owl:Class ; rdfs:label "regulation of nuclear cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0090329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033260 ] ) ] . obo:GO_0033278 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain." ; oboInOwl:hasExactSynonym "cell proliferation in mesencephalon" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mesencepahalic cell proliferation" ; oboInOwl:id "GO:0033278" ; a owl:Class ; rdfs:label "cell proliferation in midbrain" ; rdfs:subClassOf obo:GO_0061351, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030901 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001891 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001891 ] ) ] . obo:GO_0033293 obo:IAO_0000115 "Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-)." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0033293" ; a owl:Class ; rdfs:label "monocarboxylic acid binding" ; rdfs:subClassOf obo:GO_0031406, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35757 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35757 ] ) ] . obo:GO_0033313 obo:IAO_0000115 "A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072411" ; oboInOwl:hasExactSynonym "meiotic cell cycle checkpoint", "signal transduction involved in meiotic cell cycle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033313" ; a owl:Class ; rdfs:label "meiotic cell cycle checkpoint signaling" ; rdfs:subClassOf obo:GO_0000075, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000075 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0033316 obo:IAO_0000115 "A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072465" ; oboInOwl:hasExactSynonym "meiotic spindle assembly checkpoint", "signal transduction involved in meiotic spindle assembly checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033316" ; a owl:Class ; rdfs:label "meiotic spindle assembly checkpoint signaling" ; rdfs:subClassOf obo:GO_0044779, obo:GO_0071173 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071173 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0033341 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of collagen binding." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033341" ; a owl:Class ; rdfs:label "regulation of collagen binding" ; rdfs:subClassOf obo:GO_0051098, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005518 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005518 ] ) ] . obo:GO_0033342 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding." ; oboInOwl:hasExactSynonym "down regulation of collagen binding", "down-regulation of collagen binding", "downregulation of collagen binding" ; oboInOwl:hasNarrowSynonym "inhibition of collagen binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033342" ; a owl:Class ; rdfs:label "negative regulation of collagen binding" ; rdfs:subClassOf obo:GO_0033341, obo:GO_0051100, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005518 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005518 ] ) ] . obo:GO_0033343 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of collagen binding." ; oboInOwl:hasExactSynonym "up regulation of collagen binding", "up-regulation of collagen binding", "upregulation of collagen binding" ; oboInOwl:hasNarrowSynonym "activation of collagen binding", "stimulation of collagen binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033343" ; a owl:Class ; rdfs:label "positive regulation of collagen binding" ; rdfs:subClassOf obo:GO_0033341, obo:GO_0051099, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005518 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005518 ] ) ] . obo:GO_0033363 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." ; oboInOwl:hasExactSynonym "secretory granule organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "secretory granule organization and biogenesis" ; oboInOwl:id "GO:0033363" ; a owl:Class ; rdfs:label "secretory granule organization" ; rdfs:subClassOf obo:GO_0016050, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010256 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0030141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0030141 ] ) ] . obo:GO_0033365 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within an organelle." ; oboInOwl:hasExactSynonym "protein localisation to organelle", "protein localization in organelle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033365" ; a owl:Class ; rdfs:label "protein localization to organelle" ; rdfs:subClassOf obo:GO_0008104, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0033366 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within a secretory granule." ; oboInOwl:hasExactSynonym "protein localisation in secretory granule", "protein localization in secretory granule" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033366" ; a owl:Class ; rdfs:label "protein localization to secretory granule" ; rdfs:subClassOf obo:GO_0033365, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0030141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0030141 ] ) ] . obo:GO_0033371 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." ; oboInOwl:hasExactSynonym "T cell secretory granule organisation", "T lymphocyte secretory granule organization", "T-cell secretory granule organization", "T-lymphocyte secretory granule organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "T cell secretory granule organization and biogenesis", "T-lymphocyte secretory granule maturation" ; oboInOwl:id "GO:0033371" ; a owl:Class ; rdfs:label "T cell secretory granule organization" ; rdfs:subClassOf obo:GO_0033363, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000084 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0030141 ] ) ] . obo:GO_0033500 obo:IAO_0000115 "A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033500" ; a owl:Class ; rdfs:label "carbohydrate homeostasis" ; rdfs:subClassOf obo:GO_0048878, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_16646 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_16646 ] ) ] . obo:GO_0033554 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033554" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to stress" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0051716 . obo:GO_0033602 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine." ; oboInOwl:hasExactSynonym "down regulation of dopamine secretion", "down-regulation of dopamine secretion", "downregulation of dopamine secretion" ; oboInOwl:hasNarrowSynonym "inhibition of dopamine secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033602" ; a owl:Class ; rdfs:label "negative regulation of dopamine secretion" ; rdfs:subClassOf obo:GO_0014059, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014046 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014046 ] ) ] . obo:GO_0033603 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine." ; oboInOwl:hasExactSynonym "up regulation of dopamine secretion", "up-regulation of dopamine secretion", "upregulation of dopamine secretion" ; oboInOwl:hasNarrowSynonym "activation of dopamine secretion", "stimulation of dopamine secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033603" ; a owl:Class ; rdfs:label "positive regulation of dopamine secretion" ; rdfs:subClassOf obo:GO_0014059, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014046 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014046 ] ) ] . obo:GO_0033604 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine." ; oboInOwl:hasExactSynonym "down regulation of catecholamine secretion", "down-regulation of catecholamine secretion", "downregulation of catecholamine secretion" ; oboInOwl:hasNarrowSynonym "inhibition of catecholamine secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033604" ; a owl:Class ; rdfs:label "negative regulation of catecholamine secretion" ; rdfs:subClassOf obo:GO_0050433, obo:GO_0051953, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050432 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050432 ] ) ] . obo:GO_0033605 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine." ; oboInOwl:hasExactSynonym "up regulation of catecholamine secretion", "up-regulation of catecholamine secretion", "upregulation of catecholamine secretion" ; oboInOwl:hasNarrowSynonym "activation of catecholamine secretion", "stimulation of catecholamine secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033605" ; a owl:Class ; rdfs:label "positive regulation of catecholamine secretion" ; rdfs:subClassOf obo:GO_0050433, obo:GO_0051954, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050432 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050432 ] ) ] . obo:GO_0033673 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ; oboInOwl:hasExactSynonym "down regulation of kinase activity", "down-regulation of kinase activity", "downregulation of kinase activity" ; oboInOwl:hasNarrowSynonym "inhibition of kinase activity", "kinase inhibitor" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033673" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of kinase activity" ; rdfs:subClassOf obo:GO_0042326, obo:GO_0043549, obo:GO_0051348, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016301 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016301 ] ) ] . obo:GO_0033674 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ; oboInOwl:hasExactSynonym "up regulation of kinase activity", "up-regulation of kinase activity", "upregulation of kinase activity" ; oboInOwl:hasNarrowSynonym "kinase activator", "stimulation of kinase activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033674" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of kinase activity" ; rdfs:subClassOf obo:GO_0042327, obo:GO_0043549, obo:GO_0051347, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016301 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016301 ] ) ] . obo:GO_0033750 obo:IAO_0000115 "A process in which a ribosome is transported to, and/or maintained in, a specific location." ; oboInOwl:hasAlternativeId "GO:0033753" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "establishment of ribosome localisation", "establishment of ribosome localization", "ribosome localisation" ; oboInOwl:id "GO:0033750" ; a owl:Class ; rdfs:label "ribosome localization" ; rdfs:subClassOf obo:GO_0051640, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005840 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005840 ] ) ] . obo:GO_0033762 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." ; oboInOwl:hasExactSynonym "response to glucagon stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033762" ; a owl:Class ; rdfs:label "response to glucagon" ; rdfs:subClassOf obo:GO_0043434, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_5391 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_5391 ] ) ] . obo:GO_0033993 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033993" ; a owl:Class ; rdfs:label "response to lipid" ; rdfs:subClassOf obo:GO_0010033, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0034059 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%." ; oboInOwl:hasExactSynonym "response to anoxic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034059" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'response to hypoxia ; GO:0001666'." ; rdfs:label "response to anoxia" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0036293 . obo:GO_0034067 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:26:36Z" ; oboInOwl:hasAlternativeId "GO:0000042", "GO:0072600" ; oboInOwl:hasExactSynonym "protein localisation in Golgi apparatus", "protein localization in Golgi apparatus" ; oboInOwl:hasNarrowSynonym "establishment of protein localisation to Golgi", "establishment of protein localization in Golgi", "establishment of protein localization to Golgi", "establishment of protein localization to Golgi apparatus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein targeting to Golgi", "protein-Golgi targeting" ; oboInOwl:id "GO:0034067" ; a owl:Class ; rdfs:label "protein localization to Golgi apparatus" ; rdfs:subClassOf obo:GO_0033365, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005794 ] ) ] . obo:GO_0034101 obo:IAO_0000115 "Any process of regulating the production and elimination of erythrocytes within an organism." ; oboInOwl:hasExactSynonym "RBC homeostasis", "red blood cell homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034101" ; a owl:Class ; rdfs:label "erythrocyte homeostasis" ; rdfs:subClassOf obo:GO_0002262, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000232 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048872 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000232 ] ) ] . obo:GO_0034219 obo:IAO_0000115 "The process in which a carbohydrate is transported across a membrane." ; oboInOwl:hasExactSynonym "carbohydrate membrane transport", "transmembrane carbohydrate transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034219" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "carbohydrate transmembrane transport" ; rdfs:subClassOf obo:GO_0008643, obo:GO_0055085 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16646 ] ) ] . obo:GO_0034220 obo:IAO_0000115 "A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ; oboInOwl:hasAlternativeId "GO:0099131" ; oboInOwl:hasBroadSynonym "ion transmembrane transport" ; oboInOwl:hasExactSynonym "ion membrane transport", "transmembrane ion transport" ; oboInOwl:hasNarrowSynonym "ATP hydrolysis coupled ion transmembrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034220" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "monoatomic ion transmembrane transport" ; rdfs:subClassOf obo:GO_0006811, obo:GO_0055085 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24867 ] ) ] . obo:GO_0034242 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034242" ; a owl:Class ; rdfs:label "negative regulation of syncytium formation by plasma membrane fusion" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0051129, obo:GO_0060142, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000768 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000768 ] ) ] . obo:GO_0034248 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." ; oboInOwl:hasExactSynonym "regulation of amide metabolism", "regulation of cellular amide metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034248" ; a owl:Class ; rdfs:label "regulation of amide metabolic process" ; rdfs:subClassOf obo:GO_0051171, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043603 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043603 ] ) ] . obo:GO_0034249 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." ; oboInOwl:hasExactSynonym "negative regulation of amide metabolism", "negative regulation of cellular amide metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034249" ; a owl:Class ; rdfs:label "negative regulation of amide metabolic process" ; rdfs:subClassOf obo:GO_0034248, obo:GO_0051172, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043603 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043603 ] ) ] . obo:GO_0034250 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." ; oboInOwl:hasExactSynonym "positive regulation of amide metabolism", "positive regulation of cellular amide metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034250" ; a owl:Class ; rdfs:label "positive regulation of amide metabolic process" ; rdfs:subClassOf obo:GO_0034248, obo:GO_0051173, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043603 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043603 ] ) ] . obo:GO_0034251 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." ; oboInOwl:hasExactSynonym "regulation of amide breakdown", "regulation of amide catabolism", "regulation of amide degradation", "regulation of cellular amide catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034251" ; a owl:Class ; rdfs:label "regulation of amide catabolic process" ; rdfs:subClassOf obo:GO_0009894, obo:GO_0034248, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043605 ] ) ] . obo:GO_0034252 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." ; oboInOwl:hasExactSynonym "negative regulation of amide breakdown", "negative regulation of amide catabolism", "negative regulation of cellular amide catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of amide degradation" ; oboInOwl:id "GO:0034252" ; a owl:Class ; rdfs:label "negative regulation of amide catabolic process" ; rdfs:subClassOf obo:GO_0009895, obo:GO_0034249, obo:GO_0034251, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043605 ] ) ] . obo:GO_0034253 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides." ; oboInOwl:hasExactSynonym "positive regulation of amide breakdown", "positive regulation of amide catabolism", "positive regulation of cellular amide catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of amide degradation" ; oboInOwl:id "GO:0034253" ; a owl:Class ; rdfs:label "positive regulation of amide catabolic process" ; rdfs:subClassOf obo:GO_0009896, obo:GO_0034250, obo:GO_0034251, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043605 ] ) ] . obo:GO_0034263 obo:IAO_0000115 "The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy." ; oboInOwl:hasExactSynonym "autophagy in response to ER stress", "autophagy in response to endoplasmic reticulum overload" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034263" ; a owl:Class ; rdfs:label "positive regulation of autophagy in response to ER overload" ; rdfs:subClassOf obo:GO_0006983, obo:GO_0010508 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006983 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006914 ] ) ] . obo:GO_0034284 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." ; oboInOwl:hasExactSynonym "response to monosaccharide stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034284" ; a owl:Class ; rdfs:label "response to monosaccharide" ; rdfs:subClassOf obo:GO_0009743, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35381 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35381 ] ) ] . obo:GO_0034329 obo:IAO_0000115 "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034329" ; a owl:Class ; rdfs:label "cell junction assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0034330, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0030054 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0030054 ] ) ] . obo:GO_0034330 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." ; oboInOwl:hasExactSynonym "cell junction assembly and maintenance", "cell junction organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell junction biogenesis" ; oboInOwl:id "GO:0034330" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic ; a owl:Class ; rdfs:label "cell junction organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0030054 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0030054 ] ) ] . obo:GO_0034349 obo:IAO_0000115 "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system." ; oboInOwl:hasExactSynonym "apoptosis of glia", "apoptosis of glial cells", "glia apoptosis", "glia programmed cell death by apoptosis", "glial cell programmed cell death by apoptosis", "programmed cell death of glia by apoptosis", "programmed cell death of glial cells by apoptosis", "programmed cell death, glia", "programmed cell death, glial cells" ; oboInOwl:hasNarrowSynonym "glial cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034349" ; a owl:Class ; rdfs:label "glial cell apoptotic process" ; rdfs:subClassOf obo:GO_0006915, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000125 ] ) ] . obo:GO_0034350 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of glial cell apoptosis" ; oboInOwl:id "GO:0034350" ; a owl:Class ; rdfs:label "regulation of glial cell apoptotic process" ; rdfs:subClassOf obo:GO_0042981, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034349 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034349 ] ) ] . obo:GO_0034351 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process." ; oboInOwl:hasExactSynonym "down regulation of glial cell apoptosis", "down-regulation of glial cell apoptosis", "downregulation of glial cell apoptosis" ; oboInOwl:hasNarrowSynonym "inhibition of glial cell apoptosis", "negative regulation of glial cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034351" ; a owl:Class ; rdfs:label "negative regulation of glial cell apoptotic process" ; rdfs:subClassOf obo:GO_0034350, obo:GO_0043066, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034349 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034349 ] ) ] . obo:GO_0034352 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process." ; oboInOwl:hasExactSynonym "up regulation of glial cell apoptosis", "up-regulation of glial cell apoptosis", "upregulation of glial cell apoptosis" ; oboInOwl:hasNarrowSynonym "activation of glial cell apoptosis", "positive regulation of glial cell apoptosis", "stimulation of glial cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034352" ; a owl:Class ; rdfs:label "positive regulation of glial cell apoptotic process" ; rdfs:subClassOf obo:GO_0034350, obo:GO_0043065, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034349 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034349 ] ) ] . obo:GO_0034390 obo:IAO_0000115 "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels." ; oboInOwl:hasExactSynonym "SMC apoptosis", "apoptosis of smooth muscle cells", "programmed cell death of smooth muscle cells by apoptosis", "programmed cell death, smooth muscle cells", "smooth muscle cell programmed cell death by apoptosis" ; oboInOwl:hasNarrowSynonym "smooth muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034390" ; a owl:Class ; rdfs:label "smooth muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010657, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000192 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000192 ] ) ] . obo:GO_0034391 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process." ; oboInOwl:hasExactSynonym "regulation of SMC apoptosis" ; oboInOwl:hasNarrowSynonym "regulation of smooth muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034391" ; a owl:Class ; rdfs:label "regulation of smooth muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010660, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034390 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034390 ] ) ] . obo:GO_0034392 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process." ; oboInOwl:hasExactSynonym "down regulation of smooth muscle cell apoptosis", "down-regulation of smooth muscle cell apoptosis", "downregulation of smooth muscle cell apoptosis", "negative regulation of SMC apoptosis" ; oboInOwl:hasNarrowSynonym "inhibition of smooth muscle cell apoptosis", "negative regulation of smooth muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034392" ; a owl:Class ; rdfs:label "negative regulation of smooth muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010656, obo:GO_0034391, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034390 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034390 ] ) ] . obo:GO_0034393 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process." ; oboInOwl:hasExactSynonym "positive regulation of SMC apoptosis", "up regulation of smooth muscle cell apoptosis", "up-regulation of smooth muscle cell apoptosis", "upregulation of smooth muscle cell apoptosis" ; oboInOwl:hasNarrowSynonym "activation of smooth muscle cell apoptosis", "positive regulation of smooth muscle cell apoptosis", "stimulation of smooth muscle cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034393" ; a owl:Class ; rdfs:label "positive regulation of smooth muscle cell apoptotic process" ; rdfs:subClassOf obo:GO_0010661, obo:GO_0034391, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034390 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034390 ] ) ] . obo:GO_0034436 obo:IAO_0000115 "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034436" ; a owl:Class ; rdfs:label "glycoprotein transport" ; rdfs:subClassOf obo:GO_0015031, obo:GO_1901264, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17089 ] ) ] . obo:GO_0034486 obo:IAO_0000115 "The process in which a solute is transported from one side of the vacuolar membrane to the other." ; oboInOwl:hasExactSynonym "vacuolar membrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034486" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "vacuolar transmembrane transport" ; rdfs:subClassOf obo:GO_0055085, [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0034487 obo:IAO_0000115 "The process in which an amino acid is transported from one side of the vacuolar membrane to the other." ; oboInOwl:hasExactSynonym "vacuolar amino acid membrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034487" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "vacuolar amino acid transmembrane transport" ; rdfs:subClassOf obo:GO_0003333, [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0005774 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0005774 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33709 ] ) ] . obo:GO_0034502 obo:IAO_0000115 "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome." ; oboInOwl:hasExactSynonym "protein localisation to chromosome" ; oboInOwl:hasNarrowSynonym "condensin localization to chromosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034502" ; a owl:Class ; rdfs:label "protein localization to chromosome" ; rdfs:subClassOf obo:GO_0033365, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005694 ] ) ] . obo:GO_0034504 obo:IAO_0000115 "A process in which a protein transports or maintains the localization of another protein to the nucleus." ; oboInOwl:creation_date "2012-11-07T15:45:54Z" ; oboInOwl:hasAlternativeId "GO:0044744" ; oboInOwl:hasExactSynonym "protein localisation to nucleus", "protein localization in cell nucleus", "protein localization in nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein targeting to nucleus" ; oboInOwl:id "GO:0034504" ; a owl:Class ; rdfs:label "protein localization to nucleus" ; rdfs:subClassOf obo:GO_0033365, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0034599 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ; oboInOwl:hasNarrowSynonym "adaptive response to oxidative stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034599" ; a owl:Class ; rdfs:label "cellular response to oxidative stress" ; rdfs:subClassOf obo:GO_0006979, obo:GO_0062197 . obo:GO_0034606 obo:IAO_0000115 "The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034606" ; a owl:Class ; rdfs:label "response to hermaphrodite contact" ; rdfs:subClassOf obo:GO_0060179 . obo:GO_0034608 obo:IAO_0000115 "Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034608" ; a owl:Class ; rdfs:label "vulval location" ; rdfs:subClassOf obo:GO_0060179 . obo:GO_0034609 obo:IAO_0000115 "Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034609" ; a owl:Class ; rdfs:label "spicule insertion" ; rdfs:subClassOf obo:GO_0060179 . obo:GO_0034613 obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:GO_0008104 ; a owl:Class ; owl:deprecated true . obo:GO_0034620 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heat shock protein activity" ; oboInOwl:id "GO:0034620" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to the signaling pathways that respond to the presence of unfolded proteins in the ER." ; rdfs:label "cellular response to unfolded protein" ; rdfs:subClassOf obo:GO_0006986, obo:GO_0035967 . obo:GO_0034641 obo:IAO_0000115 "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." ; oboInOwl:hasExactSynonym "cellular nitrogen compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034641" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "cellular nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0006807, obo:GO_0044237 . obo:GO_0034644 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." ; oboInOwl:hasExactSynonym "cellular response to UV light stimulus", "cellular response to UV radiation stimulus", "cellular response to ultraviolet light stimulus", "cellular response to ultraviolet radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034644" ; a owl:Class ; rdfs:label "cellular response to UV" ; rdfs:subClassOf obo:GO_0009411, obo:GO_0071482 . obo:GO_0034654 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "nucleobase, nucleoside, nucleotide and nucleic acid anabolism", "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis", "nucleobase, nucleoside, nucleotide and nucleic acid formation" ; oboInOwl:hasNarrowSynonym "nucleobase, nucleoside, nucleotide and nucleic acid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034654" ; a owl:Class ; rdfs:label "nucleobase-containing compound biosynthetic process" ; rdfs:subClassOf obo:GO_0006139, obo:GO_0018130, obo:GO_0019438, obo:GO_0044271, obo:GO_1901362, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_61120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_61120 ] ) ] . obo:GO_0034655 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "nucleobase, nucleoside, nucleotide and nucleic acid breakdown", "nucleobase, nucleoside, nucleotide and nucleic acid catabolism", "nucleobase, nucleoside, nucleotide and nucleic acid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process" ; oboInOwl:id "GO:0034655" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "nucleobase-containing compound catabolic process" ; rdfs:subClassOf obo:GO_0006139, obo:GO_0019439, obo:GO_0044270, obo:GO_0046700, obo:GO_1901361, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_61120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_61120 ] ) ] . obo:GO_0034672 obo:IAO_0000115 "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." ; oboInOwl:hasExactSynonym "anterior/posterior pattern specification involved in pronephric kidney development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034672" ; a owl:Class ; rdfs:label "anterior/posterior pattern specification involved in pronephros development" ; rdfs:subClassOf obo:GO_0039017, obo:GO_0072098 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009952 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ] ) ] . obo:GO_0034762 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." ; oboInOwl:hasExactSynonym "regulation of membrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034762" ; a owl:Class ; rdfs:label "regulation of transmembrane transport" ; rdfs:subClassOf obo:GO_0050794, obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0055085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0055085 ] ) ] . obo:GO_0034763 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." ; oboInOwl:hasExactSynonym "down regulation of transmembrane transport", "down-regulation of transmembrane transport", "downregulation of transmembrane transport", "negative regulation of membrane transport" ; oboInOwl:hasNarrowSynonym "inhibition of transmembrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034763" ; a owl:Class ; rdfs:label "negative regulation of transmembrane transport" ; rdfs:subClassOf obo:GO_0034762, obo:GO_0048523, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0055085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0055085 ] ) ] . obo:GO_0034764 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other." ; oboInOwl:hasExactSynonym "positive regulation of membrane transport", "up regulation of transmembrane transport", "up-regulation of transmembrane transport", "upregulation of transmembrane transport" ; oboInOwl:hasNarrowSynonym "activation of transmembrane transport", "stimulation of transmembrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034764" ; a owl:Class ; rdfs:label "positive regulation of transmembrane transport" ; rdfs:subClassOf obo:GO_0034762, obo:GO_0048522, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0055085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0055085 ] ) ] . obo:GO_0034765 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." ; oboInOwl:hasBroadSynonym "regulation of ion transmembrane transport" ; oboInOwl:hasExactSynonym "regulation of ion membrane transport", "regulation of transmembrane ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034765" ; a owl:Class ; rdfs:label "regulation of monoatomic ion transmembrane transport" ; rdfs:subClassOf obo:GO_0034762, obo:GO_0043269, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034220 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034220 ] ) ] . obo:GO_0034766 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." ; oboInOwl:hasBroadSynonym "negative regulation of ion transmembrane transport" ; oboInOwl:hasExactSynonym "down regulation of transmembrane ion transport", "down-regulation of transmembrane ion transport", "downregulation of transmembrane ion transport", "negative regulation of ion membrane transport", "negative regulation of transmembrane ion transport" ; oboInOwl:hasNarrowSynonym "inhibition of transmembrane ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034766" ; a owl:Class ; rdfs:label "negative regulation of monoatomic ion transmembrane transport" ; rdfs:subClassOf obo:GO_0034763, obo:GO_0034765, obo:GO_0043271, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034220 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034220 ] ) ] . obo:GO_0034767 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other." ; oboInOwl:hasBroadSynonym "positive regulation of ion transmembrane transport" ; oboInOwl:hasExactSynonym "positive regulation of ion membrane transport", "positive regulation of transmembrane ion transport", "up regulation of transmembrane ion transport", "up-regulation of transmembrane ion transport", "upregulation of transmembrane ion transport" ; oboInOwl:hasNarrowSynonym "activation of transmembrane ion transport", "stimulation of transmembrane ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034767" ; a owl:Class ; rdfs:label "positive regulation of monoatomic ion transmembrane transport" ; rdfs:subClassOf obo:GO_0034764, obo:GO_0034765, obo:GO_0043270, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034220 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034220 ] ) ] . obo:GO_0034769 obo:IAO_0000115 "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-13T11:27:24Z" ; oboInOwl:hasAlternativeId "GO:0060881" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "basal lamina disassembly" ; oboInOwl:id "GO:0034769" ; a owl:Class ; rdfs:comment "Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer." ; rdfs:label "basement membrane disassembly" ; rdfs:subClassOf obo:GO_0022617, obo:GO_0071711, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005604 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005604 ] ) ] . obo:GO_0034976 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." ; oboInOwl:hasExactSynonym "ER stress response", "cellular response to endoplasmic reticulum stress", "response to ER stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034976" ; a owl:Class ; rdfs:label "response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0033554 . obo:GO_0035019 obo:IAO_0000115 "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035019" ; a owl:Class ; rdfs:label "somatic stem cell population maintenance" ; rdfs:subClassOf obo:GO_0019827, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000723 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098727 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000723 ] ) ] . obo:GO_0035039 obo:IAO_0000115 "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "male pronucleus formation" ; oboInOwl:id "GO:0035039" ; a owl:Class ; rdfs:label "male pronucleus assembly" ; rdfs:subClassOf obo:GO_0006997, obo:GO_0022414, obo:GO_0070925, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007338 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0001940 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0001940 ] ) ] . obo:GO_0035040 obo:IAO_0000115 "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035040" ; a owl:Class ; rdfs:label "sperm nuclear envelope removal" ; rdfs:subClassOf obo:GO_0022414, obo:GO_0051081, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035039 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051081 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000019 ] ) ] . obo:GO_0035045 obo:IAO_0000115 "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg." ; oboInOwl:hasExactSynonym "sperm plasma membrane breakdown", "sperm plasma membrane catabolism", "sperm plasma membrane degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035045" ; a owl:Class ; rdfs:label "sperm plasma membrane disassembly" ; rdfs:subClassOf obo:GO_0007009, obo:GO_0022412, obo:GO_0030397, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007338 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0097524 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0097524 ] ) ] . obo:GO_0035046 obo:IAO_0000115 "The directed movement of the male and female pronuclei towards each other prior to their fusion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035046" ; a owl:Class ; rdfs:label "pronuclear migration" ; rdfs:subClassOf obo:GO_0007097, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007338 ] . obo:GO_0035047 obo:IAO_0000115 "The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035047" ; a owl:Class ; rdfs:label "centrosomal and pronuclear rotation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007338 ] . obo:GO_0035050 obo:IAO_0000115 "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035050" ; a owl:Class ; rdfs:label "embryonic heart tube development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048568 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004141 ] ) ] . obo:GO_0035051 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual." ; oboInOwl:hasExactSynonym "cardiac cell differentiation", "heart cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035051" ; a owl:Class ; rdfs:label "cardiocyte differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002494 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002494 ] ) ] . obo:GO_0035082 obo:IAO_0000115 "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." ; oboInOwl:hasAlternativeId "GO:0035083", "GO:0035084" ; oboInOwl:hasExactSynonym "ciliary axoneme assembly", "cilium axoneme assembly", "flagellar axoneme assembly", "flagellum axoneme assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "axoneme biogenesis", "cilium axoneme biogenesis" ; oboInOwl:id "GO:0035082" ; a owl:Class ; rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent." ; rdfs:label "axoneme assembly" ; rdfs:subClassOf obo:GO_0001578, obo:GO_0022607, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060271 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005930 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005930 ] ) ] . obo:GO_0035107 obo:IAO_0000115 "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035107" ; a owl:Class ; rdfs:label "appendage morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048736 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000026 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000026 ] ) ] . obo:GO_0035112 obo:IAO_0000115 "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "genital morphogenesis" ; oboInOwl:id "GO:0035112" ; a owl:Class ; rdfs:label "genitalia morphogenesis" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048806 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000990 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000990 ] ) ] . obo:GO_0035148 obo:IAO_0000115 "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow." ; oboInOwl:hasExactSynonym "tube lumen formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lumen formation in an anatomical structure" ; oboInOwl:id "GO:0035148" ; a owl:Class ; rdfs:label "tube formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035239 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000025 ] ) ] . obo:GO_0035176 obo:IAO_0000115 "Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group." ; oboInOwl:hasDbXref "Wikipedia:Social_behavior" ; oboInOwl:hasExactSynonym "social behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cooperative behavior" ; oboInOwl:id "GO:0035176" ; a owl:Class ; rdfs:comment "Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior." ; rdfs:label "social behavior" ; rdfs:subClassOf obo:GO_0007610, obo:GO_0051703 . obo:GO_0035177 obo:IAO_0000115 "The movement of a larva through a feeding substrate whilst feeding on food." ; oboInOwl:hasExactSynonym "larval foraging behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035177" ; a owl:Class ; rdfs:label "larval foraging behavior" ; rdfs:subClassOf obo:GO_0030537, obo:GO_0060756 . obo:GO_0035188 obo:IAO_0000115 "The emergence of an immature organism from a protective structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035188" ; a owl:Class ; rdfs:label "hatching" ; rdfs:subClassOf obo:GO_0071684, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0035190 obo:IAO_0000115 "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035190" ; a owl:Class ; rdfs:label "syncytial nuclear migration" ; rdfs:subClassOf obo:GO_0007097, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001700 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000228 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007097 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000228 ] ) ] . obo:GO_0035234 obo:IAO_0000115 "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo." ; oboInOwl:hasExactSynonym "programmed cell death of ectopic germ cells", "programmed cell death, ectopic germ cells" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035234" ; a owl:Class ; rdfs:label "ectopic germ cell programmed cell death" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0010623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000586 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0012501 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000586 ] ) ] . obo:GO_0035239 obo:IAO_0000115 "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035239" ; a owl:Class ; rdfs:label "tube morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035295 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000025 ] ) ] . obo:GO_0035240 obo:IAO_0000115 "Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0035240" ; a owl:Class ; rdfs:label "dopamine binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_59905 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_59905 ] ) ] . obo:GO_0035260 obo:IAO_0000115 "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035260" ; a owl:Class ; rdfs:label "internal genitalia morphogenesis" ; rdfs:subClassOf obo:GO_0035112, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004175 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004175 ] ) ] . obo:GO_0035261 obo:IAO_0000115 "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035261" ; a owl:Class ; rdfs:label "external genitalia morphogenesis" ; rdfs:subClassOf obo:GO_0035112, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004176 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004176 ] ) ] . obo:GO_0035262 obo:IAO_0000115 "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035262" ; a owl:Class ; rdfs:label "gonad morphogenesis" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008406 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000991 ] ) ] . obo:GO_0035264 obo:IAO_0000115 "The increase in size or mass of an entire multicellular organism, as opposed to cell growth." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "body growth" ; oboInOwl:id "GO:0035264" ; a owl:Class ; rdfs:label "multicellular organism growth" ; rdfs:subClassOf obo:GO_0032501, obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000468 ] ) ] . obo:GO_0035265 obo:IAO_0000115 "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035265" ; a owl:Class ; rdfs:label "organ growth" ; rdfs:subClassOf obo:GO_0032501, obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000062 ] ) ] . obo:GO_0035270 obo:IAO_0000115 "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035270" ; a owl:Class ; rdfs:label "endocrine system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000949 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000949 ] ) ] . obo:GO_0035272 obo:IAO_0000115 "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035272" ; a owl:Class ; rdfs:label "exocrine system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002330 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002330 ] ) ] . obo:GO_0035282 obo:IAO_0000115 "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis." ; oboInOwl:hasDbXref "Wikipedia:Segmentation_(biology)" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035282" ; a owl:Class ; rdfs:label "segmentation" ; rdfs:subClassOf obo:GO_0003002 . obo:GO_0035290 obo:IAO_0000115 "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035290" ; a owl:Class ; rdfs:label "trunk segmentation" ; rdfs:subClassOf obo:GO_0035282, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007350 ] . obo:GO_0035295 obo:IAO_0000115 "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035295" ; a owl:Class ; rdfs:label "tube development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000025 ] ) ] . obo:GO_0035372 obo:IAO_0000115 "A process in which a protein is transported to, or maintained at, a microtubule." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-03-11T11:00:56Z" ; oboInOwl:hasExactSynonym "protein localisation to microtubule" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035372" ; a owl:Class ; rdfs:label "protein localization to microtubule" ; rdfs:subClassOf obo:GO_0072698, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005874 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0035418 obo:IAO_0000115 "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-03-29T10:58:53Z" ; oboInOwl:hasExactSynonym "protein localisation to synapse" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035418" ; a owl:Class ; rdfs:label "protein localization to synapse" ; rdfs:subClassOf obo:GO_1902414, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0035433 obo:IAO_0000115 "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-04-08T10:59:01Z" ; oboInOwl:hasExactSynonym "acetate membrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035433" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "acetate transmembrane transport" ; rdfs:subClassOf obo:GO_0006846, obo:GO_1905039 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_30089 ] ) ] . obo:GO_0035435 obo:IAO_0000115 "The process in which a phosphate is transported across a membrane." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-04-08T11:24:06Z" ; oboInOwl:hasExactSynonym "phosphate ion membrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035435" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "phosphate ion transmembrane transport" ; rdfs:subClassOf obo:GO_0006817, obo:GO_0098661 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35780 ] ) ] . obo:GO_0035437 obo:IAO_0000115 "Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-04-09T10:39:49Z" ; oboInOwl:hasExactSynonym "maintenance of protein localisation in endoplasmic reticulum", "maintenance of protein localization in ER", "maintenance of protein location in ER", "maintenance of protein location in endoplasmic reticulum", "protein-ER retention", "protein-endoplasmic reticulum retention", "retention of protein in ER", "retention of protein in endoplasmic reticulum" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035437" ; a owl:Class ; rdfs:label "maintenance of protein localization in endoplasmic reticulum" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070972 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005783 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005783 ] ) ] . obo:GO_0035441 obo:IAO_0000115 "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-04-09T03:53:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035441" ; a owl:Class ; rdfs:label "cell migration involved in vasculogenesis" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001570 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001570 ] ) ] . obo:GO_0035556 obo:IAO_0000115 "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-05-14T01:14:37Z" ; oboInOwl:hasAlternativeId "GO:0007242", "GO:0007243", "GO:0023013", "GO:0023034" ; oboInOwl:hasExactSynonym "intracellular signaling chain" ; oboInOwl:hasNarrowSynonym "intracellular protein kinase cascade", "intracellular signal transduction pathway", "protein kinase cascade", "signal transmission via intracellular cascade" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intracellular signaling cascade", "intracellular signaling pathway", "signal transduction via intracellular signaling cascade" ; oboInOwl:id "GO:0035556" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "intracellular signal transduction" ; rdfs:subClassOf obo:GO_0007165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007165 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0035561 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-05-19T10:28:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035561" ; a owl:Class ; rdfs:label "regulation of chromatin binding" ; rdfs:subClassOf obo:GO_0051098, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003682 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003682 ] ) ] . obo:GO_0035562 obo:IAO_0000115 "Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-05-19T10:29:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035562" ; a owl:Class ; rdfs:label "negative regulation of chromatin binding" ; rdfs:subClassOf obo:GO_0035561, obo:GO_0051100, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003682 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003682 ] ) ] . obo:GO_0035563 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-05-19T10:29:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035563" ; a owl:Class ; rdfs:label "positive regulation of chromatin binding" ; rdfs:subClassOf obo:GO_0035561, obo:GO_0051099, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003682 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003682 ] ) ] . obo:GO_0035592 obo:IAO_0000115 "The directed movement of a protein to a specific location within the extracellular region." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-11-09T10:25:08Z" ; oboInOwl:hasExactSynonym "establishment of protein localisation in extracellular region", "establishment of protein localization in extracellular region" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035592" ; a owl:Class ; rdfs:label "establishment of protein localization to extracellular region" ; rdfs:subClassOf obo:GO_0045184, obo:GO_0071692 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045184 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005576 ] ) ] . obo:GO_0035622 obo:IAO_0000115 "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver)." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-12-08T04:10:50Z" ; oboInOwl:hasExactSynonym "IHBD development", "intrahepatic biliary duct development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035622" ; a owl:Class ; rdfs:label "intrahepatic bile duct development" ; rdfs:subClassOf obo:GO_0061009, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001889 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003704 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003704 ] ) ] . obo:GO_0035628 obo:IAO_0000115 "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-12-10T01:24:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035628" ; a owl:Class ; rdfs:label "cystic duct development" ; rdfs:subClassOf obo:GO_0061009, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001152 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001152 ] ) ] . obo:GO_0035645 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-01-21T02:58:58Z" ; oboInOwl:hasExactSynonym "intestinal smooth muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035645" ; a owl:Class ; rdfs:label "enteric smooth muscle cell differentiation" ; rdfs:subClassOf obo:GO_0051145, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048565 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002504 ] ) ] . obo:GO_0035694 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-02-28T11:06:40Z" ; oboInOwl:hasExactSynonym "catabolism of mitochondrial protein", "degradation of damaged mitochondrial protein" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035694" ; a owl:Class ; rdfs:label "mitochondrial protein catabolic process" ; rdfs:subClassOf obo:GO_0030163, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007005 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030163 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0035701 obo:IAO_0000115 "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-02-28T03:20:36Z" ; oboInOwl:hasExactSynonym "hemopoietic stem cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035701" ; a owl:Class ; rdfs:label "hematopoietic stem cell migration" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000037 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000037 ] ) ] . obo:GO_0035725 obo:IAO_0000115 "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-03-10T02:52:36Z" ; oboInOwl:hasExactSynonym "sodium ion membrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035725" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "sodium ion transmembrane transport" ; rdfs:subClassOf obo:GO_0006814, obo:GO_0098655, obo:GO_0098662 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055085 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29101 ] ) ] . obo:GO_0035735 obo:IAO_0000115 "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-03-17T10:55:42Z" ; oboInOwl:hasBroadSynonym "intraflagellar transport" ; oboInOwl:hasDbXref "Reactome:R-HSA-5620924.2" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intraciliary transport involved in cilium morphogenesis", "intraflagellar transport involved in cilium morphogenesis" ; oboInOwl:id "GO:0035735" ; a owl:Class ; rdfs:label "intraciliary transport involved in cilium assembly" ; rdfs:subClassOf obo:GO_0042073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042073 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060271 ] ) ] . obo:GO_0035736 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-03-17T10:57:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035736" ; a owl:Class ; rdfs:label "cell proliferation involved in compound eye morphogenesis" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001745 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001745 ] ) ] . obo:GO_0035767 obo:IAO_0000115 "The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-03-31T04:31:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035767" ; a owl:Class ; rdfs:label "endothelial cell chemotaxis" ; rdfs:subClassOf obo:GO_0043542, obo:GO_0060326 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006935 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000115 ] ) ] . obo:GO_0035770 obo:IAO_0000115 "A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-01T10:50:47Z" ; oboInOwl:hasExactSynonym "RNP granule", "mRNP granule" ; oboInOwl:hasNarrowSynonym "RNA granule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0035770" ; a owl:Class ; rdfs:label "ribonucleoprotein granule" ; rdfs:subClassOf obo:GO_0043232, obo:GO_0099080 . obo:GO_0035773 obo:IAO_0000115 "The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-01T01:14:40Z" ; oboInOwl:hasExactSynonym "insulin secretion involved in cellular response to glucose" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035773" ; a owl:Class ; rdfs:label "insulin secretion involved in cellular response to glucose stimulus" ; rdfs:subClassOf obo:GO_0030073, obo:GO_0051649, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071333 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030073 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071333 ] ) ] . obo:GO_0035774 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-01T01:49:09Z" ; oboInOwl:hasExactSynonym "positive regulation of insulin secretion in response to glucose" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035774" ; a owl:Class ; rdfs:label "positive regulation of insulin secretion involved in cellular response to glucose stimulus" ; rdfs:subClassOf obo:GO_0032024, obo:GO_0061178, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035773 ] ) ] . obo:GO_0035778 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-04T11:07:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035778" ; a owl:Class ; rdfs:label "pronephric nephron tubule epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0039014, obo:GO_0072160, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0039020 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000090 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000090 ] ) ] . obo:GO_0035779 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells)." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-04T11:10:38Z" ; oboInOwl:hasExactSynonym "angioblastic mesenchymal cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035779" ; a owl:Class ; rdfs:label "angioblast cell differentiation" ; rdfs:subClassOf obo:GO_0048863, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001568 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000566 ] ) ] . obo:GO_0035787 obo:IAO_0000115 "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-06T10:39:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035787" ; a owl:Class ; rdfs:label "cell migration involved in kidney development" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0035788 obo:IAO_0000115 "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-06T10:42:21Z" ; oboInOwl:hasExactSynonym "cell migration involved in metanephric kidney development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035788" ; a owl:Class ; rdfs:label "cell migration involved in metanephros development" ; rdfs:subClassOf obo:GO_0035787, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ) ] . obo:GO_0035799 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-14T01:13:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035799" ; a owl:Class ; rdfs:label "ureter maturation" ; rdfs:subClassOf obo:GO_0048799, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072189 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071695 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000056 ] ) ] . obo:GO_0035805 obo:IAO_0000115 "A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-19T02:07:23Z" ; oboInOwl:hasNarrowSynonym "vitelline membrane", "zona pellucida" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0035805" ; a owl:Class ; rdfs:label "egg coat" ; rdfs:subClassOf obo:GO_0031012, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000025 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031012 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000025 ] ) ] . obo:GO_0035809 obo:IAO_0000115 "Any process that modulates the amount of urine excreted from the body over a unit of time." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-20T01:17:38Z" ; oboInOwl:hasExactSynonym "regulation of urinary volume", "regulation of urine flow" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035809" ; a owl:Class ; rdfs:label "regulation of urine volume" ; rdfs:subClassOf obo:GO_0003014, obo:GO_0050878 . obo:GO_0035825 obo:IAO_0000115 "A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/18777"^^xsd:anyURI ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-04T01:23:31Z" ; oboInOwl:hasDbXref "Wikipedia:Chromosomal_crossover" ; oboInOwl:hasExactSynonym "interchromosomal DNA recombination", "interstrand DNA recombination" ; oboInOwl:hasNarrowSynonym "reciprocal DNA recombination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosomal crossover" ; oboInOwl:id "GO:0035825" ; a owl:Class ; rdfs:label "homologous recombination" ; rdfs:subClassOf obo:GO_0006310 . obo:GO_0035834 obo:IAO_0000115 "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-04T03:17:44Z" ; oboInOwl:hasExactSynonym "indole alkaloid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035834" ; a owl:Class ; rdfs:label "indole alkaloid metabolic process" ; rdfs:subClassOf obo:GO_0009820, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_38958 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_38958 ] ) ] . obo:GO_0035835 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-04T03:18:31Z" ; oboInOwl:hasExactSynonym "indole alkaloid anabolism", "indole alkaloid biosynthesis", "indole alkaloid formation", "indole alkaloid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035835" ; a owl:Class ; rdfs:label "indole alkaloid biosynthetic process" ; rdfs:subClassOf obo:GO_0009821, obo:GO_0035834, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_38958 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_38958 ] ) ] . obo:GO_0035844 obo:IAO_0000115 "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-06T01:54:35Z" ; oboInOwl:hasExactSynonym "cloacal development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035844" ; a owl:Class ; rdfs:label "cloaca development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001655 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048546 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000162 ] ) ] . obo:GO_0035846 obo:IAO_0000115 "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-10T10:53:05Z" ; oboInOwl:hasNarrowSynonym "fallopian tube epithelium development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035846" ; a owl:Class ; rdfs:label "oviduct epithelium development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060066 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004804 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004804 ] ) ] . obo:GO_0035847 obo:IAO_0000115 "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-10T10:57:45Z" ; oboInOwl:hasExactSynonym "uterus epithelial development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035847" ; a owl:Class ; rdfs:label "uterine epithelium development" ; rdfs:subClassOf obo:GO_0035846, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060065 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006955 ] ) ] . obo:GO_0035848 obo:IAO_0000115 "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-10T11:01:20Z" ; oboInOwl:hasNarrowSynonym "fallopian tube morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035848" ; a owl:Class ; rdfs:label "oviduct morphogenesis" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0009887, obo:GO_0035239, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060066 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000993 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000993 ] ) ] . obo:GO_0035850 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-11T11:34:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035850" ; a owl:Class ; rdfs:label "epithelial cell differentiation involved in kidney development" ; rdfs:subClassOf obo:GO_0030855, obo:GO_0061005 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030855 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0035855 obo:IAO_0000115 "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-13T01:28:06Z" ; oboInOwl:hasExactSynonym "megakaryocyte cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035855" ; a owl:Class ; rdfs:label "megakaryocyte development" ; rdfs:subClassOf obo:GO_0061515, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030219 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000556 ] ) ] . obo:GO_0035869 obo:IAO_0000115 "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-25T03:09:58Z" ; oboInOwl:hasExactSynonym "cilial transition zone", "cilium transition zone" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "connecting cilium" ; oboInOwl:id "GO:0035869" ; a owl:Class ; rdfs:comment "Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone." ; rdfs:label "ciliary transition zone" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005929 ] . obo:GO_0035882 obo:IAO_0000115 "The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-06T11:36:35Z" ; oboInOwl:hasExactSynonym "DMP", "defecation cycle", "defecation motor program" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "defecation behavior" ; oboInOwl:id "GO:0035882" ; a owl:Class ; rdfs:label "defecation rhythm" ; rdfs:subClassOf obo:GO_0007624, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030421 ] . obo:GO_0035883 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-06T11:48:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035883" ; a owl:Class ; rdfs:label "enteroendocrine cell differentiation" ; rdfs:subClassOf obo:GO_0002067, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000164 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000164 ] ) ] . obo:GO_0035886 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-08T11:23:52Z" ; oboInOwl:hasExactSynonym "VSMC differentiation", "vascular smooth muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035886" ; a owl:Class ; rdfs:label "vascular associated smooth muscle cell differentiation" ; rdfs:subClassOf obo:GO_0051145, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001944 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000359 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000359 ] ) ] . obo:GO_0035887 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-08T11:34:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035887" ; a owl:Class ; rdfs:label "aortic smooth muscle cell differentiation" ; rdfs:subClassOf obo:GO_0035886, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002539 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002539 ] ) ] . obo:GO_0035904 obo:IAO_0000115 "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-24T11:00:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035904" ; a owl:Class ; rdfs:label "aorta development" ; rdfs:subClassOf obo:GO_0060840, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000947 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000947 ] ) ] . obo:GO_0035905 obo:IAO_0000115 "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-24T11:02:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035905" ; a owl:Class ; rdfs:label "ascending aorta development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035904 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001496 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001496 ] ) ] . obo:GO_0035906 obo:IAO_0000115 "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-24T11:05:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035906" ; a owl:Class ; rdfs:label "descending aorta development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035904 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001514 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001514 ] ) ] . obo:GO_0035907 obo:IAO_0000115 "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-24T11:07:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035907" ; a owl:Class ; rdfs:label "dorsal aorta development" ; rdfs:subClassOf obo:GO_0035904, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005805 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005805 ] ) ] . obo:GO_0035909 obo:IAO_0000115 "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-24T11:11:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035909" ; a owl:Class ; rdfs:label "aorta morphogenesis" ; rdfs:subClassOf obo:GO_0048844, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035904 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000947 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000947 ] ) ] . obo:GO_0035910 obo:IAO_0000115 "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-24T11:14:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035910" ; a owl:Class ; rdfs:label "ascending aorta morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035905 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035909 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001496 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001496 ] ) ] . obo:GO_0035911 obo:IAO_0000115 "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-24T11:19:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035911" ; a owl:Class ; rdfs:label "descending aorta morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035906 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035909 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001514 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001514 ] ) ] . obo:GO_0035912 obo:IAO_0000115 "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-24T11:22:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035912" ; a owl:Class ; rdfs:label "dorsal aorta morphogenesis" ; rdfs:subClassOf obo:GO_0035909, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035907 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005805 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005805 ] ) ] . obo:GO_0035914 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-24T02:36:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035914" ; a owl:Class ; rdfs:label "skeletal muscle cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007519 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000188 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000188 ] ) ] . obo:GO_0035915 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-07-01T11:45:01Z" ; oboInOwl:hasExactSynonym "pore complex assembly in other organism", "pore complex biogenesis in other organism", "pore formation in membrane of other organism", "pore formation in other organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pore-forming toxin activity" ; oboInOwl:id "GO:0035915" ; a owl:Class ; rdfs:label "pore formation in membrane of another organism" ; rdfs:subClassOf obo:GO_0051673 . obo:GO_0035929 obo:IAO_0000115 "The regulated release of any steroid that acts as a hormone into the circulatory system." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-07-20T01:01:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035929" ; a owl:Class ; rdfs:label "steroid hormone secretion" ; rdfs:subClassOf obo:GO_0060986, obo:GO_0140353, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_26764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_26764 ] ) ] . obo:GO_0035935 obo:IAO_0000115 "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-07-20T01:11:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035935" ; a owl:Class ; rdfs:label "androgen secretion" ; rdfs:subClassOf obo:GO_0035929 . obo:GO_0035966 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-08-03T11:43:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to misfolded or unfolded protein" ; oboInOwl:id "GO:0035966" ; a owl:Class ; rdfs:label "response to topologically incorrect protein" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0010033 . obo:GO_0035967 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-08-03T11:44:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular response to misfolded or unfolded protein" ; oboInOwl:id "GO:0035967" ; a owl:Class ; rdfs:label "cellular response to topologically incorrect protein" ; rdfs:subClassOf obo:GO_0033554, obo:GO_0035966, obo:GO_0071310 . obo:GO_0035987 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-08-25T04:50:36Z" ; oboInOwl:hasExactSynonym "endoderm cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035987" ; a owl:Class ; rdfs:label "endodermal cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001706 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000223 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000223 ] ) ] . obo:GO_0035989 obo:IAO_0000115 "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-08-26T04:14:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "sinew development" ; oboInOwl:id "GO:0035989" ; a owl:Class ; rdfs:label "tendon development" ; rdfs:subClassOf obo:GO_0061448, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000043 ] ) ] . obo:GO_0035992 obo:IAO_0000115 "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-08-30T01:35:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035992" ; a owl:Class ; rdfs:label "tendon formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035989 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000043 ] ) ] . obo:GO_0036072 obo:IAO_0000115 "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-12-19T01:47:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036072" ; a owl:Class ; rdfs:label "direct ossification" ; rdfs:subClassOf obo:GO_0001503 . obo:GO_0036093 obo:IAO_0000115 "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-01-17T04:06:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036093" ; a owl:Class ; rdfs:label "germ cell proliferation" ; rdfs:subClassOf obo:GO_0008283, obo:GO_0022412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007276 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000586 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000586 ] ) ] . obo:GO_0036094 obo:IAO_0000115 "Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-01-17T04:20:34Z" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0036094" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon ; a owl:Class ; rdfs:comment "Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides." ; rdfs:label "small molecule binding" ; rdfs:subClassOf obo:GO_0005488 . obo:GO_0036099 obo:IAO_0000115 "The process by which an organism or tissue maintains a population of female germ-line stem cells." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-01-26T01:58:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036099" ; a owl:Class ; rdfs:label "female germ-line stem cell population maintenance" ; rdfs:subClassOf obo:GO_0030718, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098727 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000022 ] ) ] . obo:GO_0036145 obo:IAO_0000115 "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-03-12T11:05:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DC homeostasis" ; oboInOwl:id "GO:0036145" ; a owl:Class ; rdfs:label "dendritic cell homeostasis" ; rdfs:subClassOf obo:GO_0001776, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000451 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048872 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000451 ] ) ] . obo:GO_0036194 obo:IAO_0000115 "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-04-20T10:20:47Z" ; oboInOwl:hasExactSynonym "myocyte projection" ; oboInOwl:hasNarrowSynonym "muscle arm", "myopodia" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0036194" ; a owl:Class ; rdfs:label "muscle cell projection" ; rdfs:subClassOf obo:GO_0120025, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000187 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0120025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:GO_0036195 obo:IAO_0000115 "The portion of the plasma membrane surrounding a muscle cell projection." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-04-20T10:21:51Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0036195" ; a owl:Class ; rdfs:label "muscle cell projection membrane" ; rdfs:subClassOf obo:GO_0031253, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0036194 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031253 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0036194 ] ) ] . obo:GO_0036211 obo:IAO_0000115 "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-04-26T01:47:12Z" ; oboInOwl:hasAlternativeId "GO:0006464" ; oboInOwl:hasExactSynonym "cellular protein modification process", "process resulting in protein modification", "protein modification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036211" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_pir, go:goslim_plant, go:prokaryote_subset ; a owl:Class ; rdfs:label "protein modification process" ; rdfs:subClassOf obo:GO_0019538, obo:GO_0043412 . obo:GO_0036276 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-07-09T02:12:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036276" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to antidepressant" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0036293 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-07-20T01:05:46Z" ; oboInOwl:hasExactSynonym "response to lowered oxygen levels" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036293" ; a owl:Class ; rdfs:comment "This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'." ; rdfs:label "response to decreased oxygen levels" ; rdfs:subClassOf obo:GO_0070482 . obo:GO_0036304 obo:IAO_0000115 "The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-08-08T10:12:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036304" ; a owl:Class ; rdfs:label "umbilical cord morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002331 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002331 ] ) ] . obo:GO_0036333 obo:IAO_0000115 "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-09-05T10:17:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036333" ; a owl:Class ; rdfs:label "hepatocyte homeostasis" ; rdfs:subClassOf obo:GO_0048872, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000182 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048872 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000182 ] ) ] . obo:GO_0036334 obo:IAO_0000115 "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-09-05T10:21:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036334" ; a owl:Class ; rdfs:label "epidermal stem cell homeostasis" ; rdfs:subClassOf obo:GO_0048872, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_1000428 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048872 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_1000428 ] ) ] . obo:GO_0036336 obo:IAO_0000115 "The movement of a dendritic cell within or between different tissues and organs of the body." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-09-05T10:24:46Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036336" ; a owl:Class ; rdfs:label "dendritic cell migration" ; rdfs:subClassOf obo:GO_0071674, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000451 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000451 ] ) ] . obo:GO_0036379 obo:IAO_0000115 "Any of the smallest contractile units of a myofibril (striated muscle fiber)." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2013-05-22T14:39:06Z" ; oboInOwl:hasExactSynonym "striated muscle filament" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0036379" ; a owl:Class ; rdfs:label "myofilament" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030016 ] . obo:GO_0036464 obo:IAO_0000115 "A ribonucleoprotein granule located in the cytoplasm." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-06-18T09:44:44Z" ; oboInOwl:hasNarrowSynonym "Staufen granule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0036464" ; a owl:Class ; rdfs:label "cytoplasmic ribonucleoprotein granule" ; rdfs:subClassOf obo:GO_0035770, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0035770 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0036465 obo:IAO_0000115 "The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-06-26T11:03:08Z" ; oboInOwl:hasNarrowSynonym "kiss-and-run synaptic vesicle recycling", "kiss-and-stay synaptic vesicle recycling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036465" ; a owl:Class ; rdfs:label "synaptic vesicle recycling" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0051649, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099504 ] . obo:GO_0036477 obo:IAO_0000115 "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-07-24T10:06:19Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0036477" ; a owl:Class ; rdfs:label "somatodendritic compartment" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000540 ] . obo:GO_0036484 obo:IAO_0000115 "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-08-26T15:27:44Z" ; oboInOwl:hasExactSynonym "trunk NCC migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036484" ; a owl:Class ; rdfs:label "trunk neural crest cell migration" ; rdfs:subClassOf obo:GO_0001755, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035290 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000011 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000011 ] ) ] . obo:GO_0036490 obo:IAO_0000115 "Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2015-02-05T09:50:11Z" ; oboInOwl:hasExactSynonym "regulation of translation in response to ER stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036490" ; a owl:Class ; rdfs:label "regulation of translation in response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0043555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034976 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034976 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0036493 obo:IAO_0000115 "Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2015-02-05T10:09:51Z" ; oboInOwl:hasExactSynonym "positive regulation of translation in response to ER stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036493" ; a owl:Class ; rdfs:label "positive regulation of translation in response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0032056, obo:GO_0036490 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034976 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0036504 obo:IAO_0000115 "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2015-05-21T10:05:06Z" ; oboInOwl:hasExactSynonym "Golgi apparatus membrane fusion", "membrane fusion involved in Golgi reassembly", "post-mitotic fusion of Golgi membranes" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036504" ; a owl:Class ; rdfs:label "Golgi membrane fusion" ; rdfs:subClassOf obo:GO_0090174, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0090168 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0000139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061025 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0000139 ] ) ] . obo:GO_0038024 obo:IAO_0000115 "Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-08-01T02:50:45Z" ; oboInOwl:hasBroadSynonym "receptor activity", "transport receptor activity" ; oboInOwl:hasDbXref "Reactome:R-HSA-3000103", "Reactome:R-HSA-3000112", "Reactome:R-HSA-3000122", "Reactome:R-HSA-3000137", "Reactome:R-HSA-350168", "Reactome:R-HSA-9759202", "Reactome:R-HSA-9759209" ; oboInOwl:hasNarrowSynonym "endocytic receptor activity", "receptor activity involved in receptor-mediated endocytosis" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0038024" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic ; a owl:Class ; rdfs:comment "Notes: (1) this term and its child terms are intended for receptors that bind to and internalize molecules by receptor-mediated endocytosis. For receptors that are coupled to a signal transduction pathway, consider instead the term 'signaling receptor activity ; GO:0038023' and its children. (2) Cargo receptors transport substances by vesicular transport, not by transmembrane transport. For transmembrane transporters, consider instead the term 'transmembrane transporter activity ; GO:0022857." ; rdfs:label "cargo receptor activity" ; rdfs:subClassOf obo:GO_0003674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006897 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0060090 ] . obo:GO_0039006 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T09:37:27Z" ; oboInOwl:hasExactSynonym "pronephric tubule formation", "pronephros tubule formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039006" ; a owl:Class ; rdfs:label "pronephric nephron tubule formation" ; rdfs:subClassOf obo:GO_0072079, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0039008 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072116 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005310 ] ) ] . obo:GO_0039007 obo:IAO_0000115 "The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T09:38:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039007" ; a owl:Class ; rdfs:label "pronephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0039019 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072114 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005309 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005309 ] ) ] . obo:GO_0039008 obo:IAO_0000115 "The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T09:45:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039008" ; a owl:Class ; rdfs:label "pronephric nephron tubule morphogenesis" ; rdfs:subClassOf obo:GO_0072078, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0039007 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0039020 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005310 ] ) ] . obo:GO_0039014 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T09:59:25Z" ; oboInOwl:hasExactSynonym "cell differentiation involved in pronephric kidney development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039014" ; a owl:Class ; rdfs:label "cell differentiation involved in pronephros development" ; rdfs:subClassOf obo:GO_0061005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ] ) ] . obo:GO_0039015 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T10:01:49Z" ; oboInOwl:hasExactSynonym "cell proliferation involved in pronephric kidney development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039015" ; a owl:Class ; rdfs:label "cell proliferation involved in pronephros development" ; rdfs:subClassOf obo:GO_0072111, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ] ) ] . obo:GO_0039016 obo:IAO_0000115 "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T10:03:16Z" ; oboInOwl:hasExactSynonym "cell-cell signaling involved in pronephric kidney development", "cell-cell signalling involved in pronephros development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039016" ; a owl:Class ; rdfs:label "cell-cell signaling involved in pronephros development" ; rdfs:subClassOf obo:GO_0060995, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ] ) ] . obo:GO_0039017 obo:IAO_0000115 "Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T10:04:39Z" ; oboInOwl:hasExactSynonym "pattern specification involved in pronephric kidney development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039017" ; a owl:Class ; rdfs:label "pattern specification involved in pronephros development" ; rdfs:subClassOf obo:GO_0061004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007389 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ] ) ] . obo:GO_0039019 obo:IAO_0000115 "The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T10:10:20Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039019" ; a owl:Class ; rdfs:label "pronephric nephron development" ; rdfs:subClassOf obo:GO_0072006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005309 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005309 ] ) ] . obo:GO_0039020 obo:IAO_0000115 "The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T10:11:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039020" ; a owl:Class ; rdfs:label "pronephric nephron tubule development" ; rdfs:subClassOf obo:GO_0072080, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0039019 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005310 ] ) ] . obo:GO_0039022 obo:IAO_0000115 "The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T10:15:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039022" ; a owl:Class ; rdfs:label "pronephric duct development" ; rdfs:subClassOf obo:GO_0072176, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003060 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003060 ] ) ] . obo:GO_0039023 obo:IAO_0000115 "The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-07-02T10:18:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0039023" ; a owl:Class ; rdfs:label "pronephric duct morphogenesis" ; rdfs:subClassOf obo:GO_0072178, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0039022 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072114 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003060 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003060 ] ) ] . obo:GO_0040001 obo:IAO_0000115 "The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs." ; oboInOwl:hasAlternativeId "GO:0018986", "GO:0030605", "GO:0030606", "GO:0030608", "GO:0030610" ; oboInOwl:hasExactSynonym "establishment of mitotic spindle localisation", "mitotic spindle positioning", "mitotic spindle positioning or orientation", "spindle positioning involved in mitotic cell cycle" ; oboInOwl:hasNarrowSynonym "mitotic spindle positioning and orientation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "spindle positioning during mitosis" ; oboInOwl:id "GO:0040001" ; a owl:Class ; rdfs:label "establishment of mitotic spindle localization" ; rdfs:subClassOf obo:GO_0051293, obo:GO_1902850 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051293 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0040002 obo:IAO_0000115 "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans." ; oboInOwl:hasExactSynonym "collagen and cuticulin-based cuticle anabolism", "collagen and cuticulin-based cuticle biosynthetic process", "collagen and cuticulin-based cuticle formation", "collagen and cuticulin-based cuticle synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040002" ; a owl:Class ; rdfs:label "collagen and cuticulin-based cuticle development" ; rdfs:subClassOf obo:GO_0042335 . obo:GO_0040004 obo:IAO_0000115 "Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans." ; oboInOwl:hasBroadSynonym "cuticular attachment to epithelium" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040004" ; a owl:Class ; rdfs:label "collagen and cuticulin-based cuticle attachment to epithelium" ; rdfs:subClassOf obo:GO_0022404, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0018996 ] . obo:GO_0040007 obo:IAO_0000115 "The increase in size or mass of an entire organism, a part of an organism or a cell." ; oboInOwl:hasAlternativeId "GO:0048590" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "growth pattern", "non-developmental growth" ; oboInOwl:id "GO:0040007" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_chembl, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:comment "See also the biological process term 'cell growth ; GO:0016049'." ; rdfs:label "growth" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_131567 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_131567 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith obo:GO_0044848 . obo:GO_0040008 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040008" ; a owl:Class ; rdfs:label "regulation of growth" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040007 ] ) ] . obo:GO_0040011 obo:IAO_0000115 "Self-propelled movement of a cell or organism from one location to another." ; obo:RO_0002161 obo:NCBITaxon_451864 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040011" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "locomotion" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_451864 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_451864 ] ] ; owl:disjointWith obo:GO_0044848, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_451864 ] . obo:GO_0040012 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040012" ; a owl:Class ; rdfs:label "regulation of locomotion" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040011 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040011 ] ) ] . obo:GO_0040013 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." ; oboInOwl:hasExactSynonym "down regulation of locomotion", "down-regulation of locomotion", "downregulation of locomotion" ; oboInOwl:hasNarrowSynonym "inhibition of locomotion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040013" ; a owl:Class ; rdfs:label "negative regulation of locomotion" ; rdfs:subClassOf obo:GO_0040012, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040011 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040011 ] ) ] . obo:GO_0040014 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size." ; oboInOwl:hasExactSynonym "regulation of body growth", "regulation of body size" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040014" ; a owl:Class ; rdfs:label "regulation of multicellular organism growth" ; rdfs:subClassOf obo:GO_0048638, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035264 ] ) ] . obo:GO_0040015 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size." ; oboInOwl:hasExactSynonym "negative regulation of body growth", "negative regulation of body size" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040015" ; a owl:Class ; rdfs:label "negative regulation of multicellular organism growth" ; rdfs:subClassOf obo:GO_0040014, obo:GO_0048640, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035264 ] ) ] . obo:GO_0040016 obo:IAO_0000115 "The first few specialized divisions of an activated animal egg." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040016" ; a owl:Class ; rdfs:label "embryonic cleavage" ; rdfs:subClassOf obo:GO_0051301, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ] . obo:GO_0040017 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." ; oboInOwl:hasExactSynonym "up regulation of locomotion", "up-regulation of locomotion", "upregulation of locomotion" ; oboInOwl:hasNarrowSynonym "activation of locomotion", "stimulation of locomotion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040017" ; a owl:Class ; rdfs:label "positive regulation of locomotion" ; rdfs:subClassOf obo:GO_0040012, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040011 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040011 ] ) ] . obo:GO_0040018 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size." ; oboInOwl:hasExactSynonym "positive regulation of body growth", "positive regulation of body size" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040018" ; a owl:Class ; rdfs:label "positive regulation of multicellular organism growth" ; rdfs:subClassOf obo:GO_0040014, obo:GO_0048639, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035264 ] ) ] . obo:GO_0040019 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of embryonic development." ; oboInOwl:hasExactSynonym "up regulation of embryonic development", "up-regulation of embryonic development", "upregulation of embryonic development" ; oboInOwl:hasNarrowSynonym "activation of embryonic development", "stimulation of embryonic development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040019" ; a owl:Class ; rdfs:label "positive regulation of embryonic development" ; rdfs:subClassOf obo:GO_0045995, obo:GO_0051094, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009790 ] ) ] . obo:GO_0040020 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." ; oboInOwl:hasBroadSynonym "regulation of meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040020" ; a owl:Class ; rdfs:label "regulation of meiotic nuclear division" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0051445, obo:GO_0051783, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0040021 obo:IAO_0000115 "The determination of sex and sexual phenotype in the germ line of a hermaphrodite." ; oboInOwl:hasAlternativeId "GO:0042005" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040021" ; a owl:Class ; rdfs:label "hermaphrodite germ-line sex determination" ; rdfs:subClassOf obo:GO_0018992 . obo:GO_0040022 obo:IAO_0000115 "The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040022" ; a owl:Class ; rdfs:label "feminization of hermaphroditic germ-line" ; rdfs:subClassOf obo:GO_0040021 . obo:GO_0040024 obo:IAO_0000115 "The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040024" ; a owl:Class ; rdfs:label "dauer larval development" ; rdfs:subClassOf obo:GO_0002119 . obo:GO_0040025 obo:IAO_0000115 "The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040025" ; a owl:Class ; rdfs:label "vulval development" ; rdfs:subClassOf obo:GO_0048569, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002119 ] . obo:GO_0040026 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of vulval development", "stimulation of vulval development", "up regulation of vulval development", "up-regulation of vulval development", "upregulation of vulval development" ; oboInOwl:id "GO:0040026" ; a owl:Class ; rdfs:label "positive regulation of vulval development" ; rdfs:subClassOf obo:GO_0040028, obo:GO_0051094, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040025 ] ) ] . obo:GO_0040027 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ; oboInOwl:hasExactSynonym "down regulation of vulval development", "down-regulation of vulval development", "downregulation of vulval development" ; oboInOwl:hasNarrowSynonym "inhibition of vulval development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040027" ; a owl:Class ; rdfs:label "negative regulation of vulval development" ; rdfs:subClassOf obo:GO_0040028, obo:GO_0061064, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040025 ] ) ] . obo:GO_0040028 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040028" ; a owl:Class ; rdfs:label "regulation of vulval development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040025 ] ) ] . obo:GO_0040029 obo:IAO_0000115 "A process that modulates the frequency, rate or extent of gene expression through chromatin remodelling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22201"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/24794"^^xsd:anyURI ; oboInOwl:hasExactSynonym "regulation of gene expression, epigenetic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040029" ; oboInOwl:inSubset go:goslim_plant ; a owl:Class ; rdfs:label "epigenetic regulation of gene expression" ; rdfs:subClassOf obo:GO_0006338, obo:GO_0010468 . obo:GO_0040034 obo:IAO_0000115 "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." ; oboInOwl:hasExactSynonym "heterochronic regulation of development", "temporal regulation of development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "developmental timing" ; oboInOwl:id "GO:0040034" ; a owl:Class ; rdfs:label "regulation of development, heterochronic" ; rdfs:subClassOf obo:GO_0050793 . obo:GO_0040038 obo:IAO_0000115 "The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040038" ; a owl:Class ; rdfs:label "polar body extrusion after meiotic divisions" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0033206, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] . obo:GO_0040040 obo:IAO_0000115 "Behavior that is dependent upon the sensation of temperature." ; oboInOwl:hasExactSynonym "behavioral response to temperature stimulus", "behavioural response to temperature stimulus", "thermosensory behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040040" ; a owl:Class ; rdfs:label "thermosensory behavior" ; rdfs:subClassOf obo:GO_0007610, obo:GO_0009266 . obo:GO_0042023 obo:IAO_0000115 "Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes." ; obo:RO_0002161 obo:NCBITaxon_4896 ; oboInOwl:hasExactSynonym "DNA endoreplication", "DNA re-duplication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042023" ; a owl:Class ; rdfs:comment "Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states." ; rdfs:label "DNA endoreduplication" ; rdfs:subClassOf obo:GO_0044786, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0006270 ] . obo:GO_0042048 obo:IAO_0000115 "The behavior of an organism in response to an odor." ; oboInOwl:hasExactSynonym "behavioral response to scent", "behavioral response to smell", "behavioural response to odour", "behavioural response to scent", "behavioural response to smell", "olfactory behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042048" ; a owl:Class ; rdfs:label "olfactory behavior" ; rdfs:subClassOf obo:GO_0007635 . obo:GO_0042053 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ; oboInOwl:hasExactSynonym "regulation of dopamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042053" ; a owl:Class ; rdfs:label "regulation of dopamine metabolic process" ; rdfs:subClassOf obo:GO_0042069, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042417 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042417 ] ) ] . obo:GO_0042063 obo:IAO_0000115 "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia." ; oboInOwl:hasExactSynonym "glial cell generation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042063" ; a owl:Class ; rdfs:label "gliogenesis" ; rdfs:subClassOf obo:GO_0022008, [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:CL_0000125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:CL_0000125 ] ) ] . obo:GO_0042065 obo:IAO_0000115 "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042065" ; a owl:Class ; rdfs:label "glial cell growth" ; rdfs:subClassOf obo:GO_0048588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042063 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:CL_0000125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040007 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:CL_0000125 ] ) ] . obo:GO_0042069 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." ; oboInOwl:hasExactSynonym "regulation of catecholamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042069" ; a owl:Class ; rdfs:label "regulation of catecholamine metabolic process" ; rdfs:subClassOf obo:GO_0031323, obo:GO_0033238, obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006584 ] ) ] . obo:GO_0042073 obo:IAO_0000115 "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." ; obo:RO_0002161 obo:NCBITaxon_3176, obo:NCBITaxon_3312, obo:NCBITaxon_3378, obo:NCBITaxon_3398, obo:NCBITaxon_4890, obo:NCBITaxon_5782 ; oboInOwl:hasAlternativeId "GO:0035734" ; oboInOwl:hasDbXref "Wikipedia:Intraflagellar_transport" ; oboInOwl:hasExactSynonym "intraflagellar transport", "intraflagellar transport involved in cilium organization", "intraflagellar transport involved in microtubule-based flagellum organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "IFT" ; oboInOwl:id "GO:0042073" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "intraciliary transport" ; rdfs:subClassOf obo:GO_0010970, obo:GO_0031503, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044782 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005929 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3176 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3312 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3378 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3398 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4890 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0032991 ] ) ] . obo:GO_0042074 obo:IAO_0000115 "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042074" ; a owl:Class ; rdfs:label "cell migration involved in gastrulation" ; rdfs:subClassOf obo:GO_0001667, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007369 ] ) ] . obo:GO_0042078 obo:IAO_0000115 "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes." ; oboInOwl:hasAlternativeId "GO:0048131" ; oboInOwl:hasExactSynonym "germ-line stem cell renewal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042078" ; a owl:Class ; rdfs:label "germ-line stem cell division" ; rdfs:subClassOf obo:GO_0017145, obo:GO_0022412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007281 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051301 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000014 ] ) ] . obo:GO_0042098 obo:IAO_0000115 "The expansion of a T cell population by cell division. Follows T cell activation." ; oboInOwl:hasAlternativeId "GO:0042111" ; oboInOwl:hasExactSynonym "T lymphocyte proliferation", "T-cell proliferation", "T-lymphocyte proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042098" ; a owl:Class ; rdfs:label "T cell proliferation" ; rdfs:subClassOf obo:GO_0042110, obo:GO_0046651, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0042102 obo:IAO_0000115 "Any process that activates or increases the rate or extent of T cell proliferation." ; oboInOwl:hasExactSynonym "positive regulation of T lymphocyte proliferation", "positive regulation of T-lymphocyte proliferation", "up regulation of T cell proliferation", "up-regulation of T cell proliferation", "upregulation of T cell proliferation" ; oboInOwl:hasNarrowSynonym "activation of T cell proliferation", "stimulation of T cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042102" ; a owl:Class ; rdfs:label "positive regulation of T cell proliferation" ; rdfs:subClassOf obo:GO_0042129, obo:GO_0050671, obo:GO_0050870, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042098 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042098 ] ) ] . obo:GO_0042103 obo:IAO_0000115 "Any process that activates or increases the rate or extent of resting T cell proliferation." ; oboInOwl:hasExactSynonym "positive regulation of T lymphocyte homeostatic proliferation", "positive regulation of T-cell homeostatic proliferation", "positive regulation of T-lymphocyte homeostatic proliferation", "positive regulation of resting T cell proliferation", "up regulation of T cell homeostatic proliferation", "up-regulation of T cell homeostatic proliferation", "upregulation of T cell homeostatic proliferation" ; oboInOwl:hasNarrowSynonym "activation of T cell homeostatic proliferation", "stimulation of T cell homeostatic proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042103" ; a owl:Class ; rdfs:label "positive regulation of T cell homeostatic proliferation" ; rdfs:subClassOf obo:GO_0042102, obo:GO_0046013, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001777 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001777 ] ) ] . obo:GO_0042110 obo:IAO_0000115 "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific." ; oboInOwl:hasExactSynonym "T lymphocyte activation", "T-cell activation", "T-lymphocyte activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042110" ; a owl:Class ; rdfs:label "T cell activation" ; rdfs:subClassOf obo:GO_0046649, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0042118 obo:IAO_0000115 "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042118" ; a owl:Class ; rdfs:label "endothelial cell activation" ; rdfs:subClassOf obo:GO_0001775, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000115 ] ) ] . obo:GO_0042127 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell proliferation." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cell proliferation" ; oboInOwl:id "GO:0042127" ; a owl:Class ; rdfs:label "regulation of cell population proliferation" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008283 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008283 ] ) ] . obo:GO_0042129 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of T cell proliferation." ; oboInOwl:hasExactSynonym "regulation of T lymphocyte proliferation", "regulation of T-cell proliferation", "regulation of T-lymphocyte proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042129" ; a owl:Class ; rdfs:label "regulation of T cell proliferation" ; rdfs:subClassOf obo:GO_0050670, obo:GO_0050863, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042098 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042098 ] ) ] . obo:GO_0042130 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of T cell proliferation." ; oboInOwl:hasExactSynonym "down regulation of T cell proliferation", "down-regulation of T cell proliferation", "downregulation of T cell proliferation", "negative regulation of T lymphocyte proliferation", "negative regulation of T-cell proliferation", "negative regulation of T-lymphocyte proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of T cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042130" ; a owl:Class ; rdfs:label "negative regulation of T cell proliferation" ; rdfs:subClassOf obo:GO_0042129, obo:GO_0050672, obo:GO_0050868, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042098 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042098 ] ) ] . obo:GO_0042133 obo:IAO_0000115 "The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasExactSynonym "neurotransmitter metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042133" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "neurotransmitter metabolic process" ; rdfs:subClassOf obo:GO_0001505, obo:GO_0044237, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4895 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] . obo:GO_0042135 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." ; oboInOwl:hasExactSynonym "neurotransmitter breakdown", "neurotransmitter catabolism", "neurotransmitter degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042135" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "neurotransmitter catabolic process" ; rdfs:subClassOf obo:GO_0042133, obo:GO_0044248 . obo:GO_0042136 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." ; oboInOwl:hasBroadSynonym "neurotransmitter biosynthesis and storage", "neurotransmitter biosynthetic process and storage" ; oboInOwl:hasExactSynonym "neurotransmitter anabolism", "neurotransmitter biosynthesis", "neurotransmitter formation", "neurotransmitter synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042136" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "neurotransmitter biosynthetic process" ; rdfs:subClassOf obo:GO_0042133, obo:GO_0044249 . obo:GO_0042165 obo:IAO_0000115 "Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0042165" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "neurotransmitter binding" ; rdfs:subClassOf obo:GO_0005488 . obo:GO_0042166 obo:IAO_0000115 "Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0042166" ; a owl:Class ; rdfs:label "acetylcholine binding" ; rdfs:subClassOf obo:GO_0042165, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_15355 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_15355 ] ) ] . obo:GO_0042175 obo:IAO_0000115 "The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane." ; oboInOwl:hasExactSynonym "nuclear membrane-ER network", "nuclear membrane-endoplasmic reticulum continuum" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "NE-ER continuum", "NE-ER network", "nuclear envelope-ER network", "nuclear envelope-endoplasmic reticulum continuum", "nuclear envelope-endoplasmic reticulum network" ; oboInOwl:id "GO:0042175" ; a owl:Class ; rdfs:label "nuclear outer membrane-endoplasmic reticulum membrane network" ; rdfs:subClassOf obo:GO_0016020, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0042176 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-08-21T15:05:45Z" ; oboInOwl:hasAlternativeId "GO:1903362", "GO:2000598" ; oboInOwl:hasExactSynonym "regulation of cellular protein breakdown", "regulation of cellular protein catabolic process", "regulation of cellular protein catabolism", "regulation of cellular protein degradation", "regulation of protein breakdown", "regulation of protein catabolism", "regulation of protein degradation" ; oboInOwl:hasNarrowSynonym "regulation of cyclin breakdown", "regulation of cyclin catabolic process", "regulation of cyclin catabolism", "regulation of cyclin degradation", "regulation of degradation of cyclin" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042176" ; a owl:Class ; rdfs:label "regulation of protein catabolic process" ; rdfs:subClassOf obo:GO_0009894, obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030163 ] ) ] . obo:GO_0042177 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:1903363", "GO:2000599" ; oboInOwl:hasExactSynonym "down regulation of cellular protein breakdown", "down regulation of cellular protein catabolic process", "down regulation of cellular protein catabolism", "down regulation of cellular protein degradation", "down regulation of protein catabolic process", "down-regulation of cellular protein breakdown", "down-regulation of cellular protein catabolic process", "down-regulation of cellular protein catabolism", "down-regulation of cellular protein degradation", "down-regulation of protein catabolic process", "downregulation of cellular protein breakdown", "downregulation of cellular protein catabolic process", "downregulation of cellular protein catabolism", "downregulation of cellular protein degradation", "downregulation of protein catabolic process", "negative regulation of cellular protein breakdown", "negative regulation of cellular protein catabolic process", "negative regulation of cellular protein catabolism", "negative regulation of cellular protein degradation", "negative regulation of protein breakdown", "negative regulation of protein catabolism", "negative regulation of protein degradation" ; oboInOwl:hasNarrowSynonym "inhibition of cellular protein breakdown", "inhibition of cellular protein catabolic process", "inhibition of cellular protein catabolism", "inhibition of cellular protein degradation", "inhibition of protein catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042177" ; a owl:Class ; rdfs:label "negative regulation of protein catabolic process" ; rdfs:subClassOf obo:GO_0009895, obo:GO_0042176, obo:GO_0051248, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030163 ] ) ] . obo:GO_0042180 obo:IAO_0000115 "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." ; oboInOwl:hasExactSynonym "ketone metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042180" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular ketone metabolic process" ; rdfs:subClassOf obo:GO_0044237, obo:GO_0044281, obo:GO_0071704, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_17087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_17087 ] ) ] . obo:GO_0042181 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." ; oboInOwl:hasExactSynonym "ketone anabolism", "ketone biosynthesis", "ketone formation", "ketone synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042181" ; a owl:Class ; rdfs:label "ketone biosynthetic process" ; rdfs:subClassOf obo:GO_0042180, obo:GO_0044249, obo:GO_0044283, obo:GO_1901576, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_17087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_17087 ] ) ] . obo:GO_0042182 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups." ; oboInOwl:hasExactSynonym "ketone breakdown", "ketone catabolism", "ketone degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042182" ; a owl:Class ; rdfs:label "ketone catabolic process" ; rdfs:subClassOf obo:GO_0042180, obo:GO_0044248, obo:GO_0044282, obo:GO_1901575, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_17087 ] ) ] . obo:GO_0042221 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ; oboInOwl:hasExactSynonym "response to chemical stimulus", "response to chemical substance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042221" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_candida, go:goslim_drosophila, go:goslim_metagenomics, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to chemical" ; rdfs:subClassOf obo:GO_0050896, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_24431 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_24431 ] ) ] . obo:GO_0042254 obo:IAO_0000115 "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis." ; oboInOwl:hasAlternativeId "GO:0007046" ; oboInOwl:hasExactSynonym "ribosome biogenesis and assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042254" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "ribosome biogenesis" ; rdfs:subClassOf obo:GO_0022613 . obo:GO_0042255 obo:IAO_0000115 "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits." ; oboInOwl:hasAlternativeId "GO:0042257" ; oboInOwl:hasNarrowSynonym "ribosomal subunit assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042255" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "ribosome assembly" ; rdfs:subClassOf obo:GO_0140694, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042254 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005840 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005840 ] ) ] . obo:GO_0042277 obo:IAO_0000115 "Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0042277" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "peptide binding" ; rdfs:subClassOf obo:GO_0033218, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16670 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0042303 obo:IAO_0000115 "The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042303" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:label "molting cycle" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0042325 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042325" ; a owl:Class ; rdfs:label "regulation of phosphorylation" ; rdfs:subClassOf obo:GO_0019220, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016310 ] ) ] . obo:GO_0042326 obo:IAO_0000115 "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." ; oboInOwl:hasExactSynonym "down regulation of phosphorylation", "down-regulation of phosphorylation", "downregulation of phosphorylation" ; oboInOwl:hasNarrowSynonym "inhibition of phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042326" ; a owl:Class ; rdfs:label "negative regulation of phosphorylation" ; rdfs:subClassOf obo:GO_0042325, obo:GO_0045936, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016310 ] ) ] . obo:GO_0042327 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." ; oboInOwl:hasExactSynonym "up regulation of phosphorylation", "up-regulation of phosphorylation", "upregulation of phosphorylation" ; oboInOwl:hasNarrowSynonym "activation of phosphorylation", "stimulation of phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042327" ; a owl:Class ; rdfs:label "positive regulation of phosphorylation" ; rdfs:subClassOf obo:GO_0042325, obo:GO_0045937, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016310 ] ) ] . obo:GO_0042330 obo:IAO_0000115 "The directed movement of a motile cell or organism in response to an external stimulus." ; oboInOwl:hasDbXref "Wikipedia:Taxis" ; oboInOwl:hasExactSynonym "directed movement in response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042330" ; a owl:Class ; rdfs:label "taxis" ; rdfs:subClassOf obo:GO_0040011, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009605 ] . obo:GO_0042331 obo:IAO_0000115 "The directed movement of a motile cell or organism in response to light." ; oboInOwl:hasAlternativeId "GO:0046953" ; oboInOwl:hasDbXref "Wikipedia:Phototaxis" ; oboInOwl:hasExactSynonym "phototactic behavior", "phototactic behaviour", "taxis in response to light" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042331" ; a owl:Class ; rdfs:label "phototaxis" ; rdfs:subClassOf obo:GO_0009416, obo:GO_0009453 . obo:GO_0042335 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss." ; oboInOwl:hasExactSynonym "cuticle anabolism", "cuticle biosynthesis", "cuticle biosynthetic process", "cuticle formation", "cuticle synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042335" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "cuticle development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0042338 obo:IAO_0000115 "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans." ; oboInOwl:hasBroadSynonym "cuticle anabolism during molting", "cuticle biosynthetic process during molting", "cuticle formation during molting", "cuticle synthesis during molting" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "collagen and cuticulin-based cuticle development during molting" ; oboInOwl:id "GO:0042338" ; a owl:Class ; rdfs:label "cuticle development involved in collagen and cuticulin-based cuticle molting cycle" ; rdfs:subClassOf obo:GO_0040002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0018996 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042335 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0018996 ] ) ] . obo:GO_0042391 obo:IAO_0000115 "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042391" ; a owl:Class ; rdfs:label "regulation of membrane potential" ; rdfs:subClassOf obo:BFO_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0034220 ] . obo:GO_0042401 obo:IAO_0000115 "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ; oboInOwl:hasExactSynonym "biogenic amine anabolism", "biogenic amine biosynthesis", "biogenic amine formation", "biogenic amine synthesis", "cellular biogenic amine biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042401" ; a owl:Class ; rdfs:label "biogenic amine biosynthetic process" ; rdfs:subClassOf obo:GO_0006576, obo:GO_0009309 . obo:GO_0042402 obo:IAO_0000115 "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ; oboInOwl:hasExactSynonym "biogenic amine breakdown", "biogenic amine catabolism", "biogenic amine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042402" ; a owl:Class ; rdfs:label "cellular biogenic amine catabolic process" ; rdfs:subClassOf obo:GO_0009310 . obo:GO_0042415 obo:IAO_0000115 "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." ; oboInOwl:hasExactSynonym "levarterenol metabolic process", "levarterenol metabolism", "noradrenaline metabolic process", "noradrenaline metabolism", "norepinephrine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042415" ; a owl:Class ; rdfs:label "norepinephrine metabolic process" ; rdfs:subClassOf obo:GO_0006807, obo:GO_0071704, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_72587 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0042416 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; oboInOwl:hasExactSynonym "dopamine anabolism", "dopamine biosynthesis", "dopamine formation", "dopamine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042416" ; a owl:Class ; rdfs:label "dopamine biosynthetic process" ; rdfs:subClassOf obo:GO_0042417, obo:GO_0042423, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_59905 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_59905 ] ) ] . obo:GO_0042417 obo:IAO_0000115 "The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; oboInOwl:hasExactSynonym "dopamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042417" ; a owl:Class ; rdfs:label "dopamine metabolic process" ; rdfs:subClassOf obo:GO_0006584, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_59905 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_59905 ] ) ] . obo:GO_0042420 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; oboInOwl:hasExactSynonym "dopamine breakdown", "dopamine catabolism", "dopamine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042420" ; a owl:Class ; rdfs:label "dopamine catabolic process" ; rdfs:subClassOf obo:GO_0042417, obo:GO_0042424, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59905 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59905 ] ) ] . obo:GO_0042421 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." ; oboInOwl:hasExactSynonym "levarterenol biosynthesis", "levarterenol biosynthetic process", "noradrenaline biosynthesis", "noradrenaline biosynthetic process", "norepinephrine anabolism", "norepinephrine biosynthesis", "norepinephrine formation", "norepinephrine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042421" ; a owl:Class ; rdfs:label "norepinephrine biosynthetic process" ; rdfs:subClassOf obo:GO_0042415, obo:GO_1901576, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_72587 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0042422 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine." ; oboInOwl:hasDbXref "Wikipedia:Norepinephrine#Degradation" ; oboInOwl:hasExactSynonym "levarterenol catabolic process", "levarterenol catabolism", "noradrenaline catabolic process", "noradrenaline catabolism", "norepinephrine breakdown", "norepinephrine catabolism", "norepinephrine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042422" ; a owl:Class ; rdfs:label "norepinephrine catabolic process" ; rdfs:subClassOf obo:GO_0042415, obo:GO_1901575, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_72587 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0042423 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; oboInOwl:hasDbXref "Wikipedia:Catecholamines" ; oboInOwl:hasExactSynonym "catecholamine anabolism", "catecholamine biosynthesis", "catecholamine formation", "catecholamine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042423" ; a owl:Class ; rdfs:label "catecholamine biosynthetic process" ; rdfs:subClassOf obo:GO_0006584, obo:GO_0009713, obo:GO_0042401, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33567 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33567 ] ) ] . obo:GO_0042424 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; oboInOwl:hasExactSynonym "catecholamine breakdown", "catecholamine catabolism", "catecholamine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042424" ; a owl:Class ; rdfs:label "catecholamine catabolic process" ; rdfs:subClassOf obo:GO_0006584, obo:GO_0019614, obo:GO_0042402, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33567 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33567 ] ) ] . obo:GO_0042427 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ; oboInOwl:hasDbXref "Wikipedia:Serotonin" ; oboInOwl:hasExactSynonym "serotonin anabolism", "serotonin biosynthesis", "serotonin formation", "serotonin synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042427" ; a owl:Class ; rdfs:label "serotonin biosynthetic process" ; rdfs:subClassOf obo:GO_0042428, obo:GO_0042435, obo:GO_0046189, obo:GO_1901162, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_350546 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_350546 ] ) ] . obo:GO_0042428 obo:IAO_0000115 "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ; oboInOwl:hasExactSynonym "serotonin metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042428" ; a owl:Class ; rdfs:label "serotonin metabolic process" ; rdfs:subClassOf obo:GO_0018958, obo:GO_0042430, obo:GO_0097164, obo:GO_1901160, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_350546 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_350546 ] ) ] . obo:GO_0042429 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ; oboInOwl:hasExactSynonym "serotonin breakdown", "serotonin catabolism", "serotonin degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042429" ; a owl:Class ; rdfs:label "serotonin catabolic process" ; rdfs:subClassOf obo:GO_0019336, obo:GO_0042428, obo:GO_0042436, obo:GO_1901161, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_350546 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_350546 ] ) ] . obo:GO_0042430 obo:IAO_0000115 "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." ; oboInOwl:hasAlternativeId "GO:0042434" ; oboInOwl:hasExactSynonym "indole and derivative metabolic process", "indole and derivative metabolism", "indole-containing compound metabolism", "ketole metabolic process", "ketole metabolism" ; oboInOwl:hasNarrowSynonym "indole derivative metabolic process", "indole derivative metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042430" ; a owl:Class ; rdfs:label "indole-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_0034641, obo:GO_0046483, obo:GO_1901360, obo:GO_1901564, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_24828 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_24828 ] ) ] . obo:GO_0042435 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." ; oboInOwl:hasExactSynonym "indole derivative biosynthesis", "indole derivative biosynthetic process", "indole-containing compound anabolism", "indole-containing compound biosynthesis", "indole-containing compound formation", "indole-containing compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042435" ; a owl:Class ; rdfs:label "indole-containing compound biosynthetic process" ; rdfs:subClassOf obo:GO_0018130, obo:GO_0019438, obo:GO_0042430, obo:GO_0044271, obo:GO_1901362, obo:GO_1901566, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_24828 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_24828 ] ) ] . obo:GO_0042436 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." ; oboInOwl:hasExactSynonym "indole derivative catabolic process", "indole derivative catabolism", "indole-containing compound breakdown", "indole-containing compound catabolism", "indole-containing compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042436" ; a owl:Class ; rdfs:label "indole-containing compound catabolic process" ; rdfs:subClassOf obo:GO_0019439, obo:GO_0042430, obo:GO_0044270, obo:GO_0046700, obo:GO_1901361, obo:GO_1901565, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24828 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24828 ] ) ] . obo:GO_0042439 obo:IAO_0000115 "The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it." ; oboInOwl:hasExactSynonym "ethanolamine and derivative metabolic process", "ethanolamine and derivative metabolism", "ethanolamine-containing compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042439" ; a owl:Class ; rdfs:label "ethanolamine-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006066, obo:GO_0006576 . obo:GO_0042445 obo:IAO_0000115 "The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23965"^^xsd:anyURI ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasAlternativeId "GO:0034754" ; oboInOwl:hasExactSynonym "hormone metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular hormone metabolic process" ; oboInOwl:id "GO:0042445" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "hormone metabolic process" ; rdfs:subClassOf obo:GO_0008152, obo:GO_0010817 . obo:GO_0042461 obo:IAO_0000115 "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light." ; oboInOwl:hasAlternativeId "GO:0046531" ; oboInOwl:hasExactSynonym "photoreceptor morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042461" ; a owl:Class ; rdfs:label "photoreceptor cell development" ; rdfs:subClassOf obo:GO_0048666, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046530 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000210 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000210 ] ) ] . obo:GO_0042462 obo:IAO_0000115 "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042462" ; a owl:Class ; rdfs:label "eye photoreceptor cell development" ; rdfs:subClassOf obo:GO_0042461, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001754 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000287 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000287 ] ) ] . obo:GO_0042478 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of eye photoreceptor development." ; oboInOwl:hasExactSynonym "regulation of eye photoreceptor development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042478" ; a owl:Class ; rdfs:label "regulation of eye photoreceptor cell development" ; rdfs:subClassOf obo:GO_0046532, obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042462 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042462 ] ) ] . obo:GO_0042479 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development." ; oboInOwl:hasExactSynonym "positive regulation of eye photoreceptor development", "up regulation of eye photoreceptor cell development", "up-regulation of eye photoreceptor cell development", "upregulation of eye photoreceptor cell development" ; oboInOwl:hasNarrowSynonym "activation of eye photoreceptor cell development", "stimulation of eye photoreceptor cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042479" ; a owl:Class ; rdfs:label "positive regulation of eye photoreceptor cell development" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0042478, obo:GO_0046534, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042462 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042462 ] ) ] . obo:GO_0042480 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development." ; oboInOwl:hasExactSynonym "down regulation of eye photoreceptor cell development", "down-regulation of eye photoreceptor cell development", "downregulation of eye photoreceptor cell development", "negative regulation of eye photoreceptor development" ; oboInOwl:hasNarrowSynonym "inhibition of eye photoreceptor cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042480" ; a owl:Class ; rdfs:label "negative regulation of eye photoreceptor cell development" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0042478, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042462 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042462 ] ) ] . obo:GO_0042493 obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:GO_0009410 ; a owl:Class ; owl:deprecated true . obo:GO_0042551 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042551" ; a owl:Class ; rdfs:label "neuron maturation" ; rdfs:subClassOf obo:GO_0048469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000540 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0042562 obo:IAO_0000115 "Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0042562" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "hormone binding" ; rdfs:subClassOf obo:GO_0005488 . obo:GO_0042579 obo:IAO_0000115 "Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2)." ; oboInOwl:hasDbXref "Wikipedia:Microbody" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042579" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "microbody" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0042588 obo:IAO_0000115 "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042588" ; a owl:Class ; rdfs:label "zymogen granule" ; rdfs:subClassOf obo:GO_0030141 . obo:GO_0042589 obo:IAO_0000115 "The lipid bilayer surrounding a zymogen granule." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042589" ; a owl:Class ; rdfs:label "zymogen granule membrane" ; rdfs:subClassOf obo:GO_0030667, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042588 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0042588 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0042588 ] ) ] . obo:GO_0042592 obo:IAO_0000115 "Any biological process involved in the maintenance of an internal steady state." ; oboInOwl:hasAlternativeId "GO:0032844", "GO:0032845", "GO:0032846" ; oboInOwl:hasExactSynonym "homeostasis" ; oboInOwl:hasNarrowSynonym "activation of homeostatic process", "inhibition of homeostatic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of homeostatic process", "positive regulation of homeostatic process", "regulation of homeostatic process" ; oboInOwl:id "GO:0042592" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_mouse ; a owl:Class ; rdfs:label "homeostatic process" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0042593 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of glucose within an organism or cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042593" ; a owl:Class ; rdfs:label "glucose homeostasis" ; rdfs:subClassOf obo:GO_0033500, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_17234 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_17234 ] ) ] . obo:GO_0042594 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042594" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "response to starvation" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0031667 . obo:GO_0042611 obo:IAO_0000115 "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042611" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "MHC protein complex" ; rdfs:subClassOf obo:GO_0098797 . obo:GO_0042613 obo:IAO_0000115 "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042613" ; a owl:Class ; rdfs:label "MHC class II protein complex" ; rdfs:subClassOf obo:GO_0042611 . obo:GO_0042641 obo:IAO_0000115 "Any complex of actin, myosin, and accessory proteins." ; oboInOwl:hasExactSynonym "actomyosin complex", "actomyosin structure" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042641" ; a owl:Class ; rdfs:label "actomyosin" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015629 ] . obo:GO_0042645 obo:IAO_0000115 "The region of a mitochondrion to which the DNA is confined." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042645" ; a owl:Class ; rdfs:label "mitochondrial nucleoid" ; rdfs:subClassOf obo:GO_0009295, obo:GO_0043232, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005759 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009295 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0042659 obo:IAO_0000115 "Any process that mediates the adoption of a specific fate by a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042659" ; a owl:Class ; rdfs:label "regulation of cell fate specification" ; rdfs:subClassOf obo:GO_0010453, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001708 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001708 ] ) ] . obo:GO_0042660 obo:IAO_0000115 "Any process that activates or enables a cell to adopt a specific fate." ; oboInOwl:hasExactSynonym "up regulation of cell fate specification", "up-regulation of cell fate specification", "upregulation of cell fate specification" ; oboInOwl:hasNarrowSynonym "activation of cell fate specification", "stimulation of cell fate specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042660" ; a owl:Class ; rdfs:label "positive regulation of cell fate specification" ; rdfs:subClassOf obo:GO_0010455, obo:GO_0042659, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001708 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001708 ] ) ] . obo:GO_0042670 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042670" ; a owl:Class ; rdfs:label "retinal cone cell differentiation" ; rdfs:subClassOf obo:GO_0060219, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000573 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000573 ] ) ] . obo:GO_0042692 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "myogenesis" ; oboInOwl:id "GO:0042692" ; a owl:Class ; rdfs:label "muscle cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061061 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000187 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:GO_0042698 obo:IAO_0000115 "The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042698" ; a owl:Class ; rdfs:label "ovulation cycle" ; rdfs:subClassOf obo:GO_0048511, obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0042702 obo:IAO_0000115 "The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042702" ; a owl:Class ; rdfs:label "uterine wall growth" ; rdfs:subClassOf obo:GO_0022602, obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001553 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000459 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040007 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000459 ] ) ] . obo:GO_0042713 obo:IAO_0000115 "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042713" ; a owl:Class ; rdfs:label "sperm ejaculation" ; rdfs:subClassOf obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007320 ] . obo:GO_0042742 obo:IAO_0000115 "Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism." ; oboInOwl:hasAlternativeId "GO:0009816", "GO:0042830" ; oboInOwl:hasExactSynonym "defence response to bacteria", "defence response to bacterium", "defense response to bacteria" ; oboInOwl:hasNarrowSynonym "defense response to bacterium, incompatible interaction", "resistance response to pathogenic bacteria", "resistance response to pathogenic bacterium" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "antibacterial peptide activity" ; oboInOwl:id "GO:0042742" ; a owl:Class ; rdfs:label "defense response to bacterium" ; rdfs:subClassOf obo:GO_0006952, obo:GO_0009617 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006952 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_2 ] ) ] . obo:GO_0042752 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042752" ; a owl:Class ; rdfs:label "regulation of circadian rhythm" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007623 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007623 ] ) ] . obo:GO_0042753 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior." ; oboInOwl:hasExactSynonym "up regulation of circadian rhythm", "up-regulation of circadian rhythm", "upregulation of circadian rhythm" ; oboInOwl:hasNarrowSynonym "activation of circadian rhythm", "stimulation of circadian rhythm" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042753" ; a owl:Class ; rdfs:label "positive regulation of circadian rhythm" ; rdfs:subClassOf obo:GO_0042752, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007623 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007623 ] ) ] . obo:GO_0042754 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior." ; oboInOwl:hasExactSynonym "down regulation of circadian rhythm", "down-regulation of circadian rhythm", "downregulation of circadian rhythm" ; oboInOwl:hasNarrowSynonym "inhibition of circadian rhythm" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042754" ; a owl:Class ; rdfs:label "negative regulation of circadian rhythm" ; rdfs:subClassOf obo:GO_0042752, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007623 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007623 ] ) ] . obo:GO_0042755 obo:IAO_0000115 "The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue." ; oboInOwl:hasExactSynonym "eating behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042755" ; a owl:Class ; rdfs:label "eating behavior" ; rdfs:subClassOf obo:GO_0007631 . obo:GO_0042762 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur." ; oboInOwl:hasExactSynonym "regulation of sulfur metabolism", "regulation of sulphur metabolic process", "regulation of sulphur metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042762" ; a owl:Class ; rdfs:label "regulation of sulfur metabolic process" ; rdfs:subClassOf obo:GO_0031323, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006790 ] ) ] . obo:GO_0042770 obo:IAO_0000115 "A cascade of processes induced by the detection of DNA damage within a cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17715"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006975" ; oboInOwl:hasExactSynonym "DNA damage response, signal transduction", "response to DNA damage stimulus by intracellular signaling cascade" ; oboInOwl:hasNarrowSynonym "DNA damage induced protein phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042770" ; a owl:Class ; rdfs:label "signal transduction in response to DNA damage" ; rdfs:subClassOf obo:GO_0006974, obo:GO_0035556 . obo:GO_0042810 obo:IAO_0000115 "The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process." ; oboInOwl:hasExactSynonym "pheromone metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042810" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "pheromone metabolic process" ; rdfs:subClassOf obo:GO_0019748, obo:GO_0042445, obo:GO_0044237 . obo:GO_0042886 obo:IAO_0000115 "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042886" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "amide transport" ; rdfs:subClassOf obo:GO_0071705, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32988 ] ) ] . obo:GO_0042887 obo:IAO_0000115 "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other." ; oboInOwl:hasNarrowSynonym "amine/amide/polyamine channel activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0042887" ; a owl:Class ; rdfs:label "amide transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0022857, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042886 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_32988 ] ) ] . obo:GO_0042981 obo:IAO_0000115 "Any process that modulates the occurrence or rate of cell death by apoptotic process." ; oboInOwl:hasNarrowSynonym "regulation of apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "apoptosis regulator activity" ; oboInOwl:id "GO:0042981" ; a owl:Class ; rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used." ; rdfs:label "regulation of apoptotic process" ; rdfs:subClassOf obo:GO_0043067, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006915 ] ) ] . obo:GO_0042995 obo:IAO_0000115 "A prolongation or process extending from a cell, e.g. a flagellum or axon." ; oboInOwl:hasBroadSynonym "cell process", "cellular process" ; oboInOwl:hasExactSynonym "cellular projection" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042995" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "cell projection" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000000 ] . obo:GO_0042996 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042996" ; a owl:Class ; rdfs:label "regulation of Golgi to plasma membrane protein transport" ; rdfs:subClassOf obo:GO_0051223, obo:GO_0060627, obo:GO_1903076, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043001 ] ) ] . obo:GO_0042997 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." ; oboInOwl:hasExactSynonym "down regulation of Golgi to plasma membrane protein transport", "down-regulation of Golgi to plasma membrane protein transport", "downregulation of Golgi to plasma membrane protein transport" ; oboInOwl:hasNarrowSynonym "inhibition of Golgi to plasma membrane protein transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042997" ; a owl:Class ; rdfs:label "negative regulation of Golgi to plasma membrane protein transport" ; rdfs:subClassOf obo:GO_0042996, obo:GO_0051224, obo:GO_1903077, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043001 ] ) ] . obo:GO_0042998 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane." ; oboInOwl:hasExactSynonym "up regulation of Golgi to plasma membrane protein transport", "up-regulation of Golgi to plasma membrane protein transport", "upregulation of Golgi to plasma membrane protein transport" ; oboInOwl:hasNarrowSynonym "activation of Golgi to plasma membrane protein transport", "stimulation of Golgi to plasma membrane protein transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042998" ; a owl:Class ; rdfs:label "positive regulation of Golgi to plasma membrane protein transport" ; rdfs:subClassOf obo:GO_0042996, obo:GO_0051222, obo:GO_1903078, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043001 ] ) ] . obo:GO_0043001 obo:IAO_0000115 "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043001" ; a owl:Class ; rdfs:label "Golgi to plasma membrane protein transport" ; rdfs:subClassOf obo:GO_0006893, obo:GO_0015031, obo:GO_0061951 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0015031 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005886 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0043005 obo:IAO_0000115 "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "NIF_Subcellular:sao867568886" ; oboInOwl:hasExactSynonym "neuron process", "neuron protrusion", "neuronal cell projection" ; oboInOwl:hasNarrowSynonym "neurite" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "nerve fiber" ; oboInOwl:id "GO:0043005" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "neuron projection" ; rdfs:subClassOf obo:GO_0120025, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000540 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0120025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0043009 obo:IAO_0000115 "The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043009" ; a owl:Class ; rdfs:label "chordate embryonic development" ; rdfs:subClassOf obo:GO_0009792, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7711 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7711 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0043010 obo:IAO_0000115 "The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." ; obo:RO_0002161 obo:NCBITaxon_6656 ; oboInOwl:hasAlternativeId "GO:0001747", "GO:0031075" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043010" ; a owl:Class ; rdfs:label "camera-type eye development" ; rdfs:subClassOf obo:GO_0001654, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_6656 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_6656 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000019 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_6656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000019 ] ) ] . obo:GO_0043021 obo:IAO_0000115 "Binding to a complex of RNA and protein." ; oboInOwl:hasExactSynonym "RNP binding", "protein-RNA complex binding", "ribonucleoprotein binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0043021" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "ribonucleoprotein complex binding" ; rdfs:subClassOf obo:GO_0044877, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_1990904 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_1990904 ] ) ] . obo:GO_0043022 obo:IAO_0000115 "Binding to a ribosome." ; oboInOwl:hasAlternativeId "GO:0030376" ; oboInOwl:hasNarrowSynonym "ribosome receptor activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0043022" ; a owl:Class ; rdfs:label "ribosome binding" ; rdfs:subClassOf obo:GO_0043021, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005840 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005840 ] ) ] . obo:GO_0043025 obo:IAO_0000115 "The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1044911821", "Wikipedia:Soma_(biology)" ; oboInOwl:hasExactSynonym "neuron cell body", "neuronal cell soma" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043025" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections." ; rdfs:label "neuronal cell body" ; rdfs:subClassOf obo:GO_0044297, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0036477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044297 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0043029 obo:IAO_0000115 "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus." ; oboInOwl:hasExactSynonym "T lymphocyte homeostasis", "T-cell homeostasis", "T-lymphocyte homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043029" ; a owl:Class ; rdfs:comment "Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus." ; rdfs:label "T cell homeostasis" ; rdfs:subClassOf obo:GO_0002260, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048872 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0043043 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." ; oboInOwl:hasExactSynonym "peptide anabolism", "peptide biosynthesis", "peptide formation", "peptide synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043043" ; a owl:Class ; rdfs:label "peptide biosynthetic process" ; rdfs:subClassOf obo:GO_0006518, obo:GO_0043604, obo:GO_1901566, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16670 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0043050 obo:IAO_0000115 "The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pumping behavior" ; oboInOwl:id "GO:0043050" ; a owl:Class ; rdfs:label "pharyngeal pumping" ; rdfs:subClassOf obo:GO_0042755 . obo:GO_0043051 obo:IAO_0000115 "Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043051" ; a owl:Class ; rdfs:label "regulation of pharyngeal pumping" ; rdfs:subClassOf obo:GO_1903998, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043050 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043050 ] ) ] . obo:GO_0043052 obo:IAO_0000115 "The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature." ; oboInOwl:hasDbXref "Wikipedia:Thermotaxis" ; oboInOwl:hasExactSynonym "taxis in response to temperature stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043052" ; a owl:Class ; rdfs:label "thermotaxis" ; rdfs:subClassOf obo:GO_0009266, obo:GO_0042330 . obo:GO_0043053 obo:IAO_0000115 "Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development." ; oboInOwl:hasExactSynonym "nematode entry into dormancy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043053" ; a owl:Class ; rdfs:label "dauer entry" ; rdfs:subClassOf obo:GO_0055115, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0040024 ] . obo:GO_0043054 obo:IAO_0000115 "Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development." ; oboInOwl:hasExactSynonym "exit from nematode dormancy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043054" ; a owl:Class ; rdfs:label "dauer exit" ; rdfs:subClassOf obo:GO_0071981, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0040024 ] . obo:GO_0043057 obo:IAO_0000115 "Posterior movement of an organism, e.g. following the direction of the tail of an animal." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043057" ; a owl:Class ; rdfs:label "backward locomotion" ; rdfs:subClassOf obo:GO_0033058 . obo:GO_0043058 obo:IAO_0000115 "Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043058" ; a owl:Class ; rdfs:label "regulation of backward locomotion" ; rdfs:subClassOf obo:GO_0040012, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043057 ] ) ] . obo:GO_0043062 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite." ; oboInOwl:hasExactSynonym "extracellular structure organisation", "extracellular structure organization and biogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043062" ; oboInOwl:inSubset go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "extracellular structure organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005576 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005576 ] ) ] . obo:GO_0043065 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." ; oboInOwl:hasExactSynonym "up regulation of apoptosis", "up-regulation of apoptosis", "upregulation of apoptosis" ; oboInOwl:hasNarrowSynonym "activation of apoptosis", "positive regulation of apoptosis", "stimulation of apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pro-apoptosis" ; oboInOwl:id "GO:0043065" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used." ; rdfs:label "positive regulation of apoptotic process" ; rdfs:subClassOf obo:GO_0042981, obo:GO_0043068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006915 ] ) ] . obo:GO_0043066 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." ; oboInOwl:hasAlternativeId "GO:0006916" ; oboInOwl:hasExactSynonym "anti-apoptosis", "down regulation of apoptosis", "down-regulation of apoptosis", "downregulation of apoptosis" ; oboInOwl:hasNarrowSynonym "inhibition of apoptosis", "negative regulation of apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "apoptosis inhibitor activity", "pro-survival" ; oboInOwl:id "GO:0043066" ; a owl:Class ; rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used." ; rdfs:label "negative regulation of apoptotic process" ; rdfs:subClassOf obo:GO_0042981, obo:GO_0043069, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006915 ] ) ] . obo:GO_0043067 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ; oboInOwl:hasAlternativeId "GO:0043070" ; oboInOwl:hasNarrowSynonym "regulation of non-apoptotic programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043067" ; a owl:Class ; rdfs:label "regulation of programmed cell death" ; rdfs:subClassOf obo:GO_0010941, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0012501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0012501 ] ) ] . obo:GO_0043068 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ; oboInOwl:hasAlternativeId "GO:0043071" ; oboInOwl:hasExactSynonym "up regulation of programmed cell death", "up-regulation of programmed cell death", "upregulation of programmed cell death" ; oboInOwl:hasNarrowSynonym "activation of programmed cell death", "positive regulation of non-apoptotic programmed cell death", "stimulation of programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043068" ; a owl:Class ; rdfs:label "positive regulation of programmed cell death" ; rdfs:subClassOf obo:GO_0010942, obo:GO_0043067, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0012501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0012501 ] ) ] . obo:GO_0043069 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ; oboInOwl:hasAlternativeId "GO:0043072" ; oboInOwl:hasExactSynonym "down regulation of programmed cell death", "down-regulation of programmed cell death", "downregulation of programmed cell death" ; oboInOwl:hasNarrowSynonym "inhibition of programmed cell death", "negative regulation of non-apoptotic programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043069" ; a owl:Class ; rdfs:label "negative regulation of programmed cell death" ; rdfs:subClassOf obo:GO_0043067, obo:GO_0060548, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0012501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0012501 ] ) ] . obo:GO_0043073 obo:IAO_0000115 "The nucleus of a germ cell, a reproductive cell in multicellular organisms." ; oboInOwl:hasExactSynonym "germ-cell nucleus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043073" ; a owl:Class ; rdfs:label "germ cell nucleus" ; rdfs:subClassOf obo:GO_0005634, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000586 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005634 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000586 ] ) ] . obo:GO_0043085 obo:IAO_0000115 "Any process that activates or increases the activity of an enzyme." ; oboInOwl:hasAlternativeId "GO:0048554" ; oboInOwl:hasExactSynonym "positive regulation of enzyme activity", "up regulation of enzyme activity", "up-regulation of enzyme activity", "upregulation of enzyme activity" ; oboInOwl:hasNarrowSynonym "activation of enzyme activity", "activation of metalloenzyme activity", "positive regulation of metalloenzyme activity", "stimulation of enzyme activity", "stimulation of metalloenzyme activity", "up regulation of metalloenzyme activity", "up-regulation of metalloenzyme activity", "upregulation of metalloenzyme activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043085" ; oboInOwl:inSubset go:goslim_chembl, go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of catalytic activity" ; rdfs:subClassOf obo:GO_0044093, obo:GO_0050790, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003824 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003824 ] ) ] . obo:GO_0043086 obo:IAO_0000115 "Any process that stops or reduces the activity of an enzyme." ; oboInOwl:hasAlternativeId "GO:0048553" ; oboInOwl:hasExactSynonym "down regulation of enzyme activity", "down-regulation of enzyme activity", "down-regulation of metalloenzyme activity", "downregulation of enzyme activity", "negative regulation of enzyme activity" ; oboInOwl:hasNarrowSynonym "down regulation of metalloenzyme activity", "downregulation of metalloenzyme activity", "inhibition of enzyme activity", "inhibition of metalloenzyme activity", "negative regulation of metalloenzyme activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043086" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of catalytic activity" ; rdfs:subClassOf obo:GO_0044092, obo:GO_0050790, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003824 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003824 ] ) ] . obo:GO_0043129 obo:IAO_0000115 "Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24222"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0050828" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of liquid surface tension", "regulation of surface tension of a liquid", "surfactant activity" ; oboInOwl:id "GO:0043129" ; a owl:Class ; rdfs:label "surfactant homeostasis" ; rdfs:subClassOf obo:GO_0048871 . obo:GO_0043133 obo:IAO_0000115 "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043133" ; a owl:Class ; rdfs:label "hindgut contraction" ; rdfs:subClassOf obo:GO_0006939, obo:GO_0022600, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001046 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006939 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001046 ] ) ] . obo:GO_0043134 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043134" ; a owl:Class ; rdfs:label "regulation of hindgut contraction" ; rdfs:subClassOf obo:GO_0006940, obo:GO_0044058, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043133 ] ) ] . obo:GO_0043143 obo:IAO_0000115 "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "establishment and maintenance of translational machinery localization", "establishment and maintenance of translational protein localization", "regulation of translation by machinery localisation", "translational machinery localization", "translational protein localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043143" ; a owl:Class ; rdfs:label "regulation of translation by machinery localization" ; rdfs:subClassOf obo:GO_0006417, obo:GO_0008104, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006412 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0043170 obo:IAO_0000115 "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasAlternativeId "GO:0034960", "GO:0043283", "GO:0044259" ; oboInOwl:hasExactSynonym "biopolymer metabolic process", "macromolecule metabolism", "organismal macromolecule metabolism" ; oboInOwl:hasNarrowSynonym "multicellular organismal macromolecule metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043170" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "macromolecule metabolic process" ; rdfs:subClassOf obo:GO_0071704, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33694 ] ) ] . obo:GO_0043171 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." ; oboInOwl:hasExactSynonym "peptide breakdown", "peptide catabolism", "peptide degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043171" ; a owl:Class ; rdfs:label "peptide catabolic process" ; rdfs:subClassOf obo:GO_0006518, obo:GO_0044248, obo:GO_1901565, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16670 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0043176 obo:IAO_0000115 "Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0043176" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "amine binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_32952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_32952 ] ) ] . obo:GO_0043177 obo:IAO_0000115 "Binding to an organic acid, any acidic compound containing carbon in covalent linkage." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0043177" ; a owl:Class ; rdfs:label "organic acid binding" ; rdfs:subClassOf obo:GO_0036094, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_64709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_64709 ] ) ] . obo:GO_0043184 obo:IAO_0000115 "Binding to a vascular endothelial growth factor receptor 2." ; oboInOwl:hasBroadSynonym "KDR binding" ; oboInOwl:hasExactSynonym "Flk-1 binding", "VEGF receptor 2 binding", "VEGFR 2 binding", "kinase domain region binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0043184" ; a owl:Class ; rdfs:label "vascular endothelial growth factor receptor 2 binding" ; rdfs:subClassOf obo:GO_0005172, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000002112 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000002112 ] ) ] . obo:GO_0043186 obo:IAO_0000115 "A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes." ; oboInOwl:hasAlternativeId "GO:0018994" ; oboInOwl:hasBroadSynonym "germline granule" ; oboInOwl:hasNarrowSynonym "nuage", "polar granule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043186" ; a owl:Class ; rdfs:label "P granule" ; rdfs:subClassOf obo:GO_0036464, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060293 ] . obo:GO_0043200 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." ; oboInOwl:hasAlternativeId "GO:0010237" ; oboInOwl:hasExactSynonym "response to amino acid stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043200" ; a owl:Class ; rdfs:label "response to amino acid" ; rdfs:subClassOf obo:GO_0001101, obo:GO_0010243, obo:GO_1901700, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33709 ] ) ] . obo:GO_0043207 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043207" ; a owl:Class ; rdfs:label "response to external biotic stimulus" ; rdfs:subClassOf obo:GO_0009605, obo:GO_0009607 . obo:GO_0043226 obo:IAO_0000115 "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1539965131", "Wikipedia:Organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043226" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "organelle" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0043227 obo:IAO_0000115 "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." ; oboInOwl:hasDbXref "NIF_Subcellular:sao414196390" ; oboInOwl:hasExactSynonym "membrane-enclosed organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043227" ; a owl:Class ; rdfs:label "membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043226, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:disjointWith obo:GO_0043228 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043226 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0043228 obo:IAO_0000115 "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21881"^^xsd:anyURI ; oboInOwl:hasDbXref "NIF_Subcellular:sao1456184038" ; oboInOwl:hasExactSynonym "non-membrane-enclosed organelle" ; oboInOwl:hasNarrowSynonym "biological condensate" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043228" ; oboInOwl:inSubset go:goslim_mouse ; a owl:Class ; rdfs:label "non-membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043226 . obo:GO_0043229 obo:IAO_0000115 "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043229" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "intracellular organelle" ; rdfs:subClassOf obo:GO_0043226, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ; owl:disjointWith obo:GO_0043230 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043226 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0043230 obo:IAO_0000115 "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043230" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "extracellular organelle" ; rdfs:subClassOf obo:GO_0043226, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005576 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043226 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005576 ] ) ] . obo:GO_0043231 obo:IAO_0000115 "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." ; oboInOwl:hasExactSynonym "intracellular membrane-enclosed organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043231" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "intracellular membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043227, obo:GO_0043229 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043227 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0043232 obo:IAO_0000115 "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." ; oboInOwl:hasExactSynonym "intracellular non-membrane-enclosed organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043232" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "intracellular non-membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043228, obo:GO_0043229 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043228 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0043233 obo:IAO_0000115 "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043233" ; oboInOwl:inSubset go:goslim_mouse ; a owl:Class ; rdfs:label "organelle lumen" ; rdfs:subClassOf obo:GO_0031974, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031974 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0043242 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ; oboInOwl:hasExactSynonym "down regulation of protein complex disassembly", "down-regulation of protein complex disassembly", "downregulation of protein complex disassembly" ; oboInOwl:hasNarrowSynonym "inhibition of protein complex disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of protein complex disassembly" ; oboInOwl:id "GO:0043242" ; a owl:Class ; rdfs:label "negative regulation of protein-containing complex disassembly" ; rdfs:subClassOf obo:GO_0043244, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032984 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032984 ] ) ] . obo:GO_0043243 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ; oboInOwl:hasExactSynonym "up regulation of protein complex disassembly", "up-regulation of protein complex disassembly", "upregulation of protein complex disassembly" ; oboInOwl:hasNarrowSynonym "activation of protein complex disassembly", "stimulation of protein complex disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of protein complex disassembly" ; oboInOwl:id "GO:0043243" ; a owl:Class ; rdfs:label "positive regulation of protein-containing complex disassembly" ; rdfs:subClassOf obo:GO_0043244, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032984 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032984 ] ) ] . obo:GO_0043244 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of protein complex disassembly" ; oboInOwl:id "GO:0043244" ; a owl:Class ; rdfs:label "regulation of protein-containing complex disassembly" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032984 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032984 ] ) ] . obo:GO_0043249 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state." ; oboInOwl:hasExactSynonym "RBC maturation", "red blood cell maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043249" ; a owl:Class ; rdfs:label "erythrocyte maturation" ; rdfs:subClassOf obo:GO_0048469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048821 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000232 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000232 ] ) ] . obo:GO_0043254 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein complex assembly." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of protein complex assembly" ; oboInOwl:id "GO:0043254" ; a owl:Class ; rdfs:label "regulation of protein-containing complex assembly" ; rdfs:subClassOf obo:GO_0044087, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0065003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0065003 ] ) ] . obo:GO_0043255 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates." ; oboInOwl:hasExactSynonym "regulation of carbohydrate anabolism", "regulation of carbohydrate biosynthesis", "regulation of carbohydrate formation", "regulation of carbohydrate synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043255" ; a owl:Class ; rdfs:label "regulation of carbohydrate biosynthetic process" ; rdfs:subClassOf obo:GO_0006109, obo:GO_0009889, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016051 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016051 ] ) ] . obo:GO_0043264 obo:IAO_0000115 "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell." ; oboInOwl:hasExactSynonym "extracellular non-membrane-enclosed organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043264" ; a owl:Class ; rdfs:label "extracellular non-membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043228, obo:GO_0043230 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043228 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005576 ] ) ] . obo:GO_0043269 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasBroadSynonym "regulation of ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043269" ; a owl:Class ; rdfs:label "regulation of monoatomic ion transport" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006811 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006811 ] ) ] . obo:GO_0043270 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of ion transport", "up-regulation of ion transport", "upregulation of ion transport" ; oboInOwl:hasNarrowSynonym "activation of ion transport", "stimulation of ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043270" ; a owl:Class ; rdfs:label "positive regulation of monoatomic ion transport" ; rdfs:subClassOf obo:GO_0043269, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006811 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006811 ] ) ] . obo:GO_0043271 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasBroadSynonym "negative regulation of ion transport" ; oboInOwl:hasExactSynonym "down regulation of ion transport", "down-regulation of ion transport", "downregulation of ion transport" ; oboInOwl:hasNarrowSynonym "inhibition of ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043271" ; a owl:Class ; rdfs:label "negative regulation of monoatomic ion transport" ; rdfs:subClassOf obo:GO_0043269, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006811 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006811 ] ) ] . obo:GO_0043277 obo:IAO_0000115 "The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte." ; oboInOwl:hasExactSynonym "apoptotic cell removal", "efferocytosis", "programmed cell clearance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043277" ; a owl:Class ; rdfs:comment "Note that unlike mammals or Drosophila, C. elegans (and many lower organisms) do not have professional macrophages/phagocytes, instead cell corpses are engulfed by neighboring cells. Cell types that can function as engulfing cells include hypodermal cells, gonadal sheath cells, pharyngeal muscle cells, and intestinal cells." ; rdfs:label "apoptotic cell clearance" ; rdfs:subClassOf obo:GO_0006909 . obo:GO_0043279 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043279" ; a owl:Class ; rdfs:label "response to alkaloid" ; rdfs:subClassOf obo:GO_0010243, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_22315 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_22315 ] ) ] . obo:GO_0043292 obo:IAO_0000115 "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." ; oboInOwl:hasExactSynonym "contractile fibre" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043292" ; a owl:Class ; rdfs:label "contractile fiber" ; rdfs:subClassOf obo:GO_0043232, obo:GO_0099512, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000187 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0043296 obo:IAO_0000115 "A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability." ; oboInOwl:hasExactSynonym "apical cell junction complex", "apical junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043296" ; a owl:Class ; rdfs:label "apical junction complex" ; rdfs:subClassOf obo:GO_0005911 . obo:GO_0043297 obo:IAO_0000115 "The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents." ; oboInOwl:hasExactSynonym "apical junction complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043297" ; a owl:Class ; rdfs:label "apical junction assembly" ; rdfs:subClassOf obo:GO_0007043, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0043296 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0043296 ] ) ] . obo:GO_0043299 obo:IAO_0000115 "The regulated exocytosis of secretory granules by a leukocyte." ; oboInOwl:hasExactSynonym "immune cell degranulation", "immune cell granule exocytosis", "leucocyte degranulation", "leukocyte granule exocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043299" ; a owl:Class ; rdfs:label "leukocyte degranulation" ; rdfs:subClassOf obo:GO_0002252, obo:GO_0045055, obo:GO_0051649, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000738 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045055 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0043300 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of leukocyte degranulation." ; oboInOwl:hasExactSynonym "regulation of immune cell degranulation", "regulation of immune cell granule exocytosis", "regulation of leucocyte degranulation", "regulation of leukocyte granule exocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043300" ; a owl:Class ; rdfs:label "regulation of leukocyte degranulation" ; rdfs:subClassOf obo:GO_0002697, obo:GO_1903305, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043299 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043299 ] ) ] . obo:GO_0043301 obo:IAO_0000115 "Any process that stops, prevents, or reduces the rate of leukocyte degranulation." ; oboInOwl:hasExactSynonym "down regulation of leukocyte degranulation", "down-regulation of leukocyte degranulation", "downregulation of leukocyte degranulation", "negative regulation of immune cell degranulation", "negative regulation of leucocyte degranulation" ; oboInOwl:hasNarrowSynonym "inhibition of leukocyte degranulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043301" ; a owl:Class ; rdfs:label "negative regulation of leukocyte degranulation" ; rdfs:subClassOf obo:GO_0002698, obo:GO_0043300, obo:GO_1903306, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043299 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043299 ] ) ] . obo:GO_0043302 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of leukocyte degranulation." ; oboInOwl:hasExactSynonym "positive regulation of immune cell degranulation", "positive regulation of leucocyte degranulation", "up regulation of leukocyte degranulation", "up-regulation of leukocyte degranulation", "upregulation of leukocyte degranulation" ; oboInOwl:hasNarrowSynonym "activation of leukocyte degranulation", "stimulation of leukocyte degranulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043302" ; a owl:Class ; rdfs:label "positive regulation of leukocyte degranulation" ; rdfs:subClassOf obo:GO_0002699, obo:GO_0043300, obo:GO_1903307, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043299 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043299 ] ) ] . obo:GO_0043353 obo:IAO_0000115 "The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus." ; oboInOwl:hasExactSynonym "enucleate RBC differentiation", "enucleate red blood cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043353" ; a owl:Class ; rdfs:label "enucleate erythrocyte differentiation" ; rdfs:subClassOf obo:GO_0030218, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000595 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000595 ] ) ] . obo:GO_0043354 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus." ; oboInOwl:hasExactSynonym "enucleate RBC maturation", "enucleate red blood cell maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043354" ; a owl:Class ; rdfs:label "enucleate erythrocyte maturation" ; rdfs:subClassOf obo:GO_0043249, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048822 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000595 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000595 ] ) ] . obo:GO_0043362 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus." ; oboInOwl:hasExactSynonym "nucleate RBC maturation", "nucleate red blood cell maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043362" ; a owl:Class ; rdfs:label "nucleate erythrocyte maturation" ; rdfs:subClassOf obo:GO_0043249, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048823 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000562 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000562 ] ) ] . obo:GO_0043363 obo:IAO_0000115 "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds." ; oboInOwl:hasExactSynonym "nucleate RBC differentiation", "nucleate red blood cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043363" ; a owl:Class ; rdfs:label "nucleate erythrocyte differentiation" ; rdfs:subClassOf obo:GO_0030218, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000562 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000562 ] ) ] . obo:GO_0043388 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)." ; oboInOwl:hasExactSynonym "up regulation of DNA binding", "up-regulation of DNA binding", "upregulation of DNA binding" ; oboInOwl:hasNarrowSynonym "activation of DNA binding", "stimulation of DNA binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043388" ; a owl:Class ; rdfs:label "positive regulation of DNA binding" ; rdfs:subClassOf obo:GO_0051099, obo:GO_0051101, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003677 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003677 ] ) ] . obo:GO_0043392 obo:IAO_0000115 "Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)." ; oboInOwl:hasExactSynonym "down regulation of DNA binding", "down-regulation of DNA binding", "downregulation of DNA binding" ; oboInOwl:hasNarrowSynonym "inhibition of DNA binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043392" ; a owl:Class ; rdfs:label "negative regulation of DNA binding" ; rdfs:subClassOf obo:GO_0051100, obo:GO_0051101, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003677 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003677 ] ) ] . obo:GO_0043393 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein binding." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043393" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of protein binding" ; rdfs:subClassOf obo:GO_0051098, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005515 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005515 ] ) ] . obo:GO_0043412 obo:IAO_0000115 "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043412" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "macromolecule modification" ; rdfs:subClassOf obo:GO_0043170 . obo:GO_0043414 obo:IAO_0000115 "The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043414" ; a owl:Class ; rdfs:label "macromolecule methylation" ; rdfs:subClassOf obo:GO_0032259, obo:GO_0043412 . obo:GO_0043434 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." ; oboInOwl:hasExactSynonym "response to peptide hormone stimulus", "response to polypeptide hormone stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043434" ; a owl:Class ; rdfs:label "response to peptide hormone" ; rdfs:subClassOf obo:GO_0009725, obo:GO_1901652, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_25905 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_25905 ] ) ] . obo:GO_0043436 obo:IAO_0000115 "The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ; oboInOwl:hasExactSynonym "keto acid metabolic process", "keto acid metabolism", "ketoacid metabolic process", "ketoacid metabolism", "oxo acid metabolic process", "oxo acid metabolism", "oxoacid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043436" ; a owl:Class ; rdfs:label "oxoacid metabolic process" ; rdfs:subClassOf obo:GO_0006082, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35406 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35406 ] ) ] . obo:GO_0043455 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." ; oboInOwl:hasExactSynonym "regulation of secondary metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043455" ; a owl:Class ; rdfs:label "regulation of secondary metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019748 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019748 ] ) ] . obo:GO_0043467 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043467" ; a owl:Class ; rdfs:label "regulation of generation of precursor metabolites and energy" ; rdfs:subClassOf obo:GO_0031323, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006091 ] ) ] . obo:GO_0043470 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043470" ; a owl:Class ; rdfs:label "regulation of carbohydrate catabolic process" ; rdfs:subClassOf obo:GO_0006109, obo:GO_0009894, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016052 ] ) ] . obo:GO_0043473 obo:IAO_0000115 "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043473" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "pigmentation" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_131567 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_131567 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0043484 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043484" ; a owl:Class ; rdfs:label "regulation of RNA splicing" ; rdfs:subClassOf obo:GO_0010468, obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008380 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008380 ] ) ] . obo:GO_0043500 obo:IAO_0000115 "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "muscle plasticity" ; oboInOwl:id "GO:0043500" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "muscle adaptation" ; rdfs:subClassOf obo:GO_0003012, obo:GO_0050896, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0002385 ] . obo:GO_0043501 obo:IAO_0000115 "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "skeletal muscle plasticity" ; oboInOwl:id "GO:0043501" ; a owl:Class ; rdfs:label "skeletal muscle adaptation" ; rdfs:subClassOf obo:GO_0014888, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001134 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043500 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001134 ] ) ] . obo:GO_0043502 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of muscle adaptation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of muscle plasticity" ; oboInOwl:id "GO:0043502" ; a owl:Class ; rdfs:label "regulation of muscle adaptation" ; rdfs:subClassOf obo:GO_0048583, obo:GO_0090257, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043500 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043500 ] ) ] . obo:GO_0043523 obo:IAO_0000115 "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." ; oboInOwl:hasExactSynonym "regulation of apoptosis of neuronal cells", "regulation of apoptosis of neurons", "regulation of neuron programmed cell death", "regulation of neuronal cell programmed cell death", "regulation of programmed cell death of neuronal cells", "regulation of programmed cell death, neurons" ; oboInOwl:hasNarrowSynonym "regulation of neuron apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043523" ; a owl:Class ; rdfs:label "regulation of neuron apoptotic process" ; rdfs:subClassOf obo:GO_0042981, obo:GO_1901214, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051402 ] ) ] . obo:GO_0043524 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." ; oboInOwl:hasExactSynonym "down regulation of neuron apoptosis", "down-regulation of neuron apoptosis", "downregulation of neuron apoptosis", "negative regulation of programmed cell death, neurons" ; oboInOwl:hasNarrowSynonym "inhibition of neuron apoptosis", "negative regulation of neuron apoptosis", "neuron survival" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043524" ; a owl:Class ; rdfs:label "negative regulation of neuron apoptotic process" ; rdfs:subClassOf obo:GO_0043066, obo:GO_0043523, obo:GO_1901215, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051402 ] ) ] . obo:GO_0043525 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." ; oboInOwl:hasExactSynonym "positive regulation of programmed cell death, neurons", "up regulation of neuron apoptosis", "up-regulation of neuron apoptosis", "upregulation of neuron apoptosis" ; oboInOwl:hasNarrowSynonym "activation of neuron apoptosis", "positive regulation of neuron apoptosis", "stimulation of neuron apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043525" ; a owl:Class ; rdfs:label "positive regulation of neuron apoptotic process" ; rdfs:subClassOf obo:GO_0043065, obo:GO_0043523, obo:GO_1901216, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051402 ] ) ] . obo:GO_0043534 obo:IAO_0000115 "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043534" ; a owl:Class ; rdfs:label "blood vessel endothelial cell migration" ; rdfs:subClassOf obo:GO_0043542, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000071 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000071 ] ) ] . obo:GO_0043535 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043535" ; a owl:Class ; rdfs:label "regulation of blood vessel endothelial cell migration" ; rdfs:subClassOf obo:GO_0010594, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043534 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043534 ] ) ] . obo:GO_0043536 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels." ; oboInOwl:hasExactSynonym "up regulation of blood vessel endothelial cell migration", "up-regulation of blood vessel endothelial cell migration", "upregulation of blood vessel endothelial cell migration" ; oboInOwl:hasNarrowSynonym "activation of blood vessel endothelial cell migration", "stimulation of blood vessel endothelial cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043536" ; a owl:Class ; rdfs:label "positive regulation of blood vessel endothelial cell migration" ; rdfs:subClassOf obo:GO_0010595, obo:GO_0043535, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043534 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043534 ] ) ] . obo:GO_0043537 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels." ; oboInOwl:hasExactSynonym "down regulation of blood vessel endothelial cell migration", "down-regulation of blood vessel endothelial cell migration", "downregulation of blood vessel endothelial cell migration" ; oboInOwl:hasNarrowSynonym "inhibition of blood vessel endothelial cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043537" ; a owl:Class ; rdfs:label "negative regulation of blood vessel endothelial cell migration" ; rdfs:subClassOf obo:GO_0010596, obo:GO_0043535, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043534 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043534 ] ) ] . obo:GO_0043542 obo:IAO_0000115 "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043542" ; a owl:Class ; rdfs:label "endothelial cell migration" ; rdfs:subClassOf obo:GO_0010631, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000115 ] ) ] . obo:GO_0043549 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043549" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of kinase activity" ; rdfs:subClassOf obo:GO_0042325, obo:GO_0051338, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016301 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016301 ] ) ] . obo:GO_0043555 obo:IAO_0000115 "Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:hasExactSynonym "translational stress response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043555" ; a owl:Class ; rdfs:label "regulation of translation in response to stress" ; rdfs:subClassOf obo:GO_0006417, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0043556 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043556" ; a owl:Class ; rdfs:label "regulation of translation in response to oxidative stress" ; rdfs:subClassOf obo:GO_0032055, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034599 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0043557 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043557" ; a owl:Class ; rdfs:label "regulation of translation in response to osmotic stress" ; rdfs:subClassOf obo:GO_0043555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071470 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071470 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0043559 obo:IAO_0000115 "Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0043559" ; a owl:Class ; rdfs:label "insulin binding" ; rdfs:subClassOf obo:GO_0005515, obo:GO_0017046, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000009054 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000009054 ] ) ] . obo:GO_0043576 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043576" ; a owl:Class ; rdfs:label "regulation of respiratory gaseous exchange" ; rdfs:subClassOf obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007585 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007585 ] ) ] . obo:GO_0043588 obo:IAO_0000115 "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." ; obo:RO_0002161 obo:NCBITaxon_50557, obo:NCBITaxon_6656 ; oboInOwl:hasExactSynonym "animal skin development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043588" ; a owl:Class ; rdfs:label "skin development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_50557 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_6656 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_50557 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_6656 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002097 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_50557 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_6656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002097 ] ) ] . obo:GO_0043589 obo:IAO_0000115 "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043589" ; a owl:Class ; rdfs:label "skin morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043588 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002097 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002097 ] ) ] . obo:GO_0043603 obo:IAO_0000115 "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." ; oboInOwl:hasExactSynonym "amide metabolism", "cellular amide metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043603" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "amide metabolic process" ; rdfs:subClassOf obo:GO_0006807, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_32988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_32988 ] ) ] . obo:GO_0043604 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043604" ; a owl:Class ; rdfs:label "amide biosynthetic process" ; rdfs:subClassOf obo:GO_0043603, obo:GO_0044271, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_32988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_32988 ] ) ] . obo:GO_0043605 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; oboInOwl:hasExactSynonym "cellular amide catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043605" ; a owl:Class ; rdfs:label "amide catabolic process" ; rdfs:subClassOf obo:GO_0009056, obo:GO_0043603, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_32988 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_32988 ] ) ] . obo:GO_0043648 obo:IAO_0000115 "The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-)." ; oboInOwl:hasExactSynonym "dicarboxylate metabolic process", "dicarboxylate metabolism", "dicarboxylic acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043648" ; a owl:Class ; rdfs:label "dicarboxylic acid metabolic process" ; rdfs:subClassOf obo:GO_0019752, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35693 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_35693 ] ) ] . obo:GO_0043649 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." ; oboInOwl:hasExactSynonym "dicarboxylate catabolic process", "dicarboxylate catabolism", "dicarboxylic acid breakdown", "dicarboxylic acid catabolism", "dicarboxylic acid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043649" ; a owl:Class ; rdfs:label "dicarboxylic acid catabolic process" ; rdfs:subClassOf obo:GO_0043648, obo:GO_0046395, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35693 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35693 ] ) ] . obo:GO_0043650 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups." ; oboInOwl:hasExactSynonym "dicarboxylate biosynthesis", "dicarboxylate biosynthetic process", "dicarboxylic acid anabolism", "dicarboxylic acid biosynthesis", "dicarboxylic acid formation", "dicarboxylic acid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043650" ; a owl:Class ; rdfs:label "dicarboxylic acid biosynthetic process" ; rdfs:subClassOf obo:GO_0043648, obo:GO_0046394, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_35693 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_35693 ] ) ] . obo:GO_0043652 obo:IAO_0000115 "The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte." ; oboInOwl:hasExactSynonym "engulfment of apoptotic cell corpse", "engulfment of cell corpse" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043652" ; a owl:Class ; rdfs:comment "This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'." ; rdfs:label "engulfment of apoptotic cell" ; rdfs:subClassOf obo:GO_0006911, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043277 ] . obo:GO_0043931 obo:IAO_0000115 "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state." ; oboInOwl:hasExactSynonym "ossification involved in skeletal development" ; oboInOwl:hasNarrowSynonym "ossification involved in bone modeling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043931" ; a owl:Class ; rdfs:label "ossification involved in bone maturation" ; rdfs:subClassOf obo:GO_0001503, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070977 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001503 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070977 ] ) ] . obo:GO_0043933 obo:IAO_0000115 "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22580"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-08T10:01:42Z" ; oboInOwl:hasAlternativeId "GO:0034600", "GO:0034621", "GO:0071822" ; oboInOwl:hasExactSynonym "protein complex subunit organisation", "protein complex subunit organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular macromolecular complex organization", "cellular macromolecular complex subunit organisation", "cellular macromolecular complex subunit organization", "macromolecular complex organization", "macromolecular complex subunit organisation", "macromolecular complex subunit organization", "protein-containing complex subunit organization" ; oboInOwl:id "GO:0043933" ; a owl:Class ; rdfs:label "protein-containing complex organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0032991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0032991 ] ) ] . obo:GO_0044042 obo:IAO_0000115 "The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues." ; oboInOwl:hasExactSynonym "glucan metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044042" ; a owl:Class ; rdfs:label "glucan metabolic process" ; rdfs:subClassOf obo:GO_0005976, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_37163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_37163 ] ) ] . obo:GO_0044057 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044057" ; a owl:Class ; rdfs:label "regulation of system process" ; rdfs:subClassOf obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003008 ] ) ] . obo:GO_0044058 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044058" ; a owl:Class ; rdfs:label "regulation of digestive system process" ; rdfs:subClassOf obo:GO_0044057, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022600 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022600 ] ) ] . obo:GO_0044060 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." ; oboInOwl:hasExactSynonym "regulation of endocrine system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044060" ; a owl:Class ; rdfs:label "regulation of endocrine process" ; rdfs:subClassOf obo:GO_0044057, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050886 ] ) ] . obo:GO_0044062 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044062" ; a owl:Class ; rdfs:label "regulation of excretion" ; rdfs:subClassOf obo:GO_0044057, obo:GO_0051046, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007588 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007588 ] ) ] . obo:GO_0044065 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044065" ; a owl:Class ; rdfs:label "regulation of respiratory system process" ; rdfs:subClassOf obo:GO_0043576, obo:GO_0044057, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003016 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003016 ] ) ] . obo:GO_0044085 obo:IAO_0000115 "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." ; oboInOwl:hasAlternativeId "GO:0071843" ; oboInOwl:hasExactSynonym "cellular component biogenesis at cellular level" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044085" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular component biogenesis" ; rdfs:subClassOf obo:GO_0071840 . obo:GO_0044087 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044087" ; a owl:Class ; rdfs:label "regulation of cellular component biogenesis" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044085 ] ) ] . obo:GO_0044088 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." ; oboInOwl:hasExactSynonym "regulation of vacuole organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of vacuole biogenesis" ; oboInOwl:id "GO:0044088" ; a owl:Class ; rdfs:label "regulation of vacuole organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007033 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007033 ] ) ] . obo:GO_0044089 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044089" ; a owl:Class ; rdfs:label "positive regulation of cellular component biogenesis" ; rdfs:subClassOf obo:GO_0044087, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044085 ] ) ] . obo:GO_0044090 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." ; oboInOwl:hasExactSynonym "positive regulation of vacuole organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of vacuole biogenesis" ; oboInOwl:id "GO:0044090" ; a owl:Class ; rdfs:label "positive regulation of vacuole organization" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0044088, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007033 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007033 ] ) ] . obo:GO_0044091 obo:IAO_0000115 "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044091" ; a owl:Class ; rdfs:label "membrane biogenesis" ; rdfs:subClassOf obo:GO_0044085, [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044085 [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0044092 obo:IAO_0000115 "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2009-04-21T04:07:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044092" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of molecular function" ; rdfs:subClassOf obo:GO_0065009, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003674 ] ) ] . obo:GO_0044093 obo:IAO_0000115 "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2009-04-21T04:11:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044093" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of molecular function" ; rdfs:subClassOf obo:GO_0065009, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003674 ] ) ] . obo:GO_0044207 obo:IAO_0000115 "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator)." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2009-10-22T02:38:55Z" ; oboInOwl:hasExactSynonym "translation initiation (ternary) complex" ; oboInOwl:hasNarrowSynonym "Met-tRNA/eIF2.GTP ternary complex" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0044207" ; a owl:Class ; rdfs:label "translation initiation ternary complex" ; rdfs:subClassOf obo:GO_1990904, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0044237 obo:IAO_0000115 "The chemical reactions and pathways by which individual cells transform chemical substances." ; oboInOwl:hasExactSynonym "cellular metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intermediary metabolism" ; oboInOwl:id "GO:0044237" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term." ; rdfs:label "cellular metabolic process" ; rdfs:subClassOf obo:GO_0008152, obo:GO_0009987 . obo:GO_0044238 obo:IAO_0000115 "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ; oboInOwl:hasExactSynonym "primary metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044238" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "primary metabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0044248 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "cellular breakdown", "cellular catabolism", "cellular degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044248" ; a owl:Class ; rdfs:label "cellular catabolic process" ; rdfs:subClassOf obo:GO_0009056, obo:GO_0044237 . obo:GO_0044249 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "cellular anabolism", "cellular biosynthesis", "cellular formation", "cellular synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044249" ; a owl:Class ; rdfs:label "cellular biosynthetic process" ; rdfs:subClassOf obo:GO_0009058, obo:GO_0044237 . obo:GO_0044258 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas." ; oboInOwl:hasExactSynonym "intestinal lipid breakdown", "intestinal lipid catabolism", "intestinal lipid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044258" ; a owl:Class ; rdfs:label "intestinal lipid catabolic process" ; rdfs:subClassOf obo:GO_0016042, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0000160 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016042 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0000160 ] ) ] . obo:GO_0044270 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds." ; oboInOwl:hasBroadSynonym "nitrogen compound breakdown", "nitrogen compound catabolism", "nitrogen compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044270" ; a owl:Class ; rdfs:label "cellular nitrogen compound catabolic process" ; rdfs:subClassOf obo:GO_0034641, obo:GO_0044248 . obo:GO_0044271 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." ; oboInOwl:hasBroadSynonym "nitrogen compound anabolism", "nitrogen compound biosynthesis", "nitrogen compound formation", "nitrogen compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044271" ; a owl:Class ; rdfs:label "cellular nitrogen compound biosynthetic process" ; rdfs:subClassOf obo:GO_0034641, obo:GO_0044249 . obo:GO_0044272 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." ; oboInOwl:hasExactSynonym "sulfur compound anabolism", "sulfur compound biosynthesis", "sulfur compound formation", "sulfur compound synthesis" ; oboInOwl:hasNarrowSynonym "sulfur biosynthesis", "sulfur biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044272" ; a owl:Class ; rdfs:label "sulfur compound biosynthetic process" ; rdfs:subClassOf obo:GO_0006790, obo:GO_0044249, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_26835 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_26835 ] ) ] . obo:GO_0044273 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione." ; oboInOwl:hasExactSynonym "sulfur compound breakdown", "sulfur compound catabolism", "sulfur compound degradation" ; oboInOwl:hasNarrowSynonym "sulfur catabolic process", "sulfur catabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044273" ; a owl:Class ; rdfs:label "sulfur compound catabolic process" ; rdfs:subClassOf obo:GO_0006790, obo:GO_0044248, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_26835 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_26835 ] ) ] . obo:GO_0044281 obo:IAO_0000115 "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-01-26T12:05:20Z" ; oboInOwl:hasExactSynonym "small molecule metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044281" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_metagenomics ; a owl:Class ; rdfs:comment "Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides." ; rdfs:label "small molecule metabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0044282 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-01-26T12:06:10Z" ; oboInOwl:hasExactSynonym "small molecule catabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044282" ; a owl:Class ; rdfs:comment "Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides." ; rdfs:label "small molecule catabolic process" ; rdfs:subClassOf obo:GO_0009056, obo:GO_0044281 . obo:GO_0044283 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-01-26T12:06:49Z" ; oboInOwl:hasExactSynonym "small molecule biosynthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044283" ; oboInOwl:inSubset go:prokaryote_subset ; a owl:Class ; rdfs:comment "Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides." ; rdfs:label "small molecule biosynthetic process" ; rdfs:subClassOf obo:GO_0009058, obo:GO_0044281 . obo:GO_0044297 obo:IAO_0000115 "The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections." ; obo:RO_0002161 obo:NCBITaxon_4890 ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-02-05T10:37:16Z" ; oboInOwl:hasDbXref "FBbt:00005107", "FMA:67301", "Wikipedia:Cell_body" ; oboInOwl:hasExactSynonym "cell soma" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0044297" ; a owl:Class ; rdfs:comment "Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections." ; rdfs:label "cell body" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000000 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4890 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ] . obo:GO_0044342 obo:IAO_0000115 "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-08-25T01:44:51Z" ; oboInOwl:hasExactSynonym "pancreatic B cell proliferation", "pancreatic beta cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044342" ; a owl:Class ; rdfs:label "type B pancreatic cell proliferation" ; rdfs:subClassOf obo:GO_0050673, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000169 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000169 ] ) ] . obo:GO_0044346 obo:IAO_0000115 "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-09-23T11:33:38Z" ; oboInOwl:hasNarrowSynonym "fibroblast apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044346" ; a owl:Class ; rdfs:label "fibroblast apoptotic process" ; rdfs:subClassOf obo:GO_0006915, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000057 ] ) ] . obo:GO_0044380 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within the cytoskeleton." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2011-12-13T11:43:24Z" ; oboInOwl:hasExactSynonym "protein localisation to cytoskeleton" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044380" ; a owl:Class ; rdfs:label "protein localization to cytoskeleton" ; rdfs:subClassOf obo:GO_0033365, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005856 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005856 ] ) ] . obo:GO_0044419 obo:IAO_0000115 "Any process evolved to enable an interaction with an organism of a different species." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20191"^^xsd:anyURI ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasExactSynonym "interaction with another species", "interspecies interaction", "interspecies interaction between organisms", "interspecies interaction with other organisms" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044419" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_candida, go:goslim_pir ; a owl:Class ; rdfs:label "biological process involved in interspecies interaction between organisms" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4895 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4895 ] . obo:GO_0044458 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a motile cilium." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2015-02-06T17:23:23Z" ; oboInOwl:hasAlternativeId "GO:1903887" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "motile primary cilia assembly", "motile primary cilia formation", "motile primary cilium assembly", "motile primary cilium formation", "nodal cilium assembly", "nodal cilium formation" ; oboInOwl:id "GO:0044458" ; a owl:Class ; rdfs:label "motile cilium assembly" ; rdfs:subClassOf obo:GO_0060271, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0031514 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0031514 ] ) ] . obo:GO_0044550 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-03-29T01:55:18Z" ; oboInOwl:hasExactSynonym "secondary metabolite biosynthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044550" ; oboInOwl:inSubset go:prokaryote_subset ; a owl:Class ; rdfs:label "secondary metabolite biosynthetic process" ; rdfs:subClassOf obo:GO_0009058, obo:GO_0019748 . obo:GO_0044565 obo:IAO_0000115 "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-04-05T04:31:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044565" ; a owl:Class ; rdfs:label "dendritic cell proliferation" ; rdfs:subClassOf obo:GO_0032943, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000451 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000451 ] ) ] . obo:GO_0044566 obo:IAO_0000115 "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-04-05T04:45:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044566" ; a owl:Class ; rdfs:label "chondrocyte activation" ; rdfs:subClassOf obo:GO_0001775, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000138 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000138 ] ) ] . obo:GO_0044703 obo:IAO_0000115 "A biological process that directly contributes to the process of producing new individuals, involving another organism." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T15:56:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044703" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "multi-organism reproductive process" ; rdfs:subClassOf obo:GO_0022414 . obo:GO_0044706 obo:IAO_0000115 "A multicellular organism process which involves another multicellular organism of the same or different species." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21459"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T16:06:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044706" ; a owl:Class ; rdfs:label "multi-multicellular organism process" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0044770 obo:IAO_0000115 "The cell cycle process by which a cell commits to entering the next cell cycle phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T12:54:59Z" ; oboInOwl:hasExactSynonym "cell cycle transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044770" ; a owl:Class ; rdfs:label "cell cycle phase transition" ; rdfs:subClassOf obo:GO_0022402 . obo:GO_0044771 obo:IAO_0000115 "The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T13:08:17Z" ; oboInOwl:hasBroadSynonym "cell cycle transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044771" ; a owl:Class ; rdfs:label "meiotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_0044770, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044770 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0044772 obo:IAO_0000115 "The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T13:09:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044772" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "mitotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_0044770, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044770 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0044773 obo:IAO_0000115 "A signal transduction process involved in mitotic DNA damage checkpoint." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T15:55:25Z" ; oboInOwl:hasAlternativeId "GO:1902402" ; oboInOwl:hasExactSynonym "intracellular signaling cascade involved in mitotic DNA damage checkpoint", "mitotic DNA damage checkpoint", "signal transduction involved in mitotic DNA damage checkpoint" ; oboInOwl:hasNarrowSynonym "intracellular signal transduction pathway involved in mitotic DNA damage checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intracellular signaling pathway involved in mitotic DNA damage checkpoint" ; oboInOwl:id "GO:0044773" ; a owl:Class ; rdfs:label "mitotic DNA damage checkpoint signaling" ; rdfs:subClassOf obo:GO_0000077, obo:GO_0044774 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0044774 obo:IAO_0000115 "A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T16:07:26Z" ; oboInOwl:hasAlternativeId "GO:0070683", "GO:1902403" ; oboInOwl:hasExactSynonym "intracellular signal transduction involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signal transduction involved in topo II checkpoint", "intracellular signal transduction pathway involved in mitotic DNA integrity checkpoint", "intracellular signaling cascade involved in mitotic DNA integrity checkpoint", "intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signaling cascade involved in topo II checkpoint", "intracellular signaling chain involved in mitotic DNA integrity checkpoint", "intracellular signaling chain involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signaling pathway involved in mitotic DNA integrity checkpoint", "mitotic DNA integrity checkpoint", "mitotic cell cycle G2/M transition decatenation checkpoint", "signal transduction involved in mitotic DNA integrity checkpoint" ; oboInOwl:hasNarrowSynonym "intracellular signal transduction pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signal transduction pathway involved in topo II checkpoint", "intracellular signal transduction pathway involved in topoisomerase II checkpoint", "intracellular signaling pathway involved in topo II checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intracellular signaling pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signaling pathway involved in topoisomerase II checkpoint", "signal transduction via intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint", "signal transduction via intracellular signaling cascade involved in topo II checkpoint" ; oboInOwl:id "GO:0044774" ; a owl:Class ; rdfs:label "mitotic DNA integrity checkpoint signaling" ; rdfs:subClassOf obo:GO_0007093, obo:GO_0031570 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031570 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0044778 obo:IAO_0000115 "A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-20T16:46:06Z" ; oboInOwl:hasExactSynonym "meiotic DNA integrity checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044778" ; a owl:Class ; rdfs:label "meiotic DNA integrity checkpoint signaling" ; rdfs:subClassOf obo:GO_0031570, obo:GO_0033313 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031570 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0044779 obo:IAO_0000115 "A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-21T14:01:28Z" ; oboInOwl:hasAlternativeId "GO:1902398" ; oboInOwl:hasExactSynonym "intracellular signal transduction involved in meiotic spindle checkpoint", "intracellular signal transduction pathway involved in meiotic spindle checkpoint", "intracellular signaling cascade involved in meiotic spindle checkpoint", "intracellular signaling pathway involved in meiotic spindle checkpoint", "meiotic spindle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044779" ; a owl:Class ; rdfs:label "meiotic spindle checkpoint signaling" ; rdfs:subClassOf obo:GO_0031577, obo:GO_0033313, obo:GO_1902103 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031577 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0044782 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-27T15:09:58Z" ; oboInOwl:hasExactSynonym "microtubule-based flagellum organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044782" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "cilium organization" ; rdfs:subClassOf obo:GO_0006996, obo:GO_0120036, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005929 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:GO_0044784 obo:IAO_0000115 "The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T13:09:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044784" ; a owl:Class ; rdfs:label "metaphase/anaphase transition of cell cycle" ; rdfs:subClassOf obo:GO_0033045, obo:GO_0044770 . obo:GO_0044785 obo:IAO_0000115 "The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T13:11:28Z" ; oboInOwl:hasExactSynonym "meiotic metaphase/anaphase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044785" ; a owl:Class ; rdfs:label "metaphase/anaphase transition of meiotic cell cycle" ; rdfs:subClassOf obo:GO_0044771, obo:GO_0044784 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044784 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0044786 obo:IAO_0000115 "The DNA-dependent DNA replication that takes place as part of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T15:52:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044786" ; a owl:Class ; rdfs:label "cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0006261, obo:GO_0022402 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006261 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0044804 obo:IAO_0000115 "A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-09-10T15:50:25Z" ; oboInOwl:hasExactSynonym "nucleus degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nucleophagy" ; oboInOwl:id "GO:0044804" ; a owl:Class ; rdfs:label "autophagy of nucleus" ; rdfs:subClassOf obo:GO_0006914, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006914 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0044818 obo:IAO_0000115 "A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-11-19T14:20:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044818" ; a owl:Class ; rdfs:label "mitotic G2/M transition checkpoint" ; rdfs:subClassOf obo:GO_0007093, obo:GO_0010972 . obo:GO_0044819 obo:IAO_0000115 "A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-11-19T14:31:14Z" ; oboInOwl:hasExactSynonym "mitotic G1/S transition checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044819" ; a owl:Class ; rdfs:label "mitotic G1/S transition checkpoint signaling" ; rdfs:subClassOf obo:GO_0007093, obo:GO_2000134 . obo:GO_0044839 obo:IAO_0000115 "The cell cycle process by which a cell in G2 phase commits to M phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-05T14:56:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044839" ; a owl:Class ; rdfs:label "cell cycle G2/M phase transition" ; rdfs:subClassOf obo:GO_0044770 . obo:GO_0044840 obo:IAO_0000115 "A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-25T11:56:41Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0044840" ; a owl:Class ; rdfs:label "gut granule" ; rdfs:subClassOf obo:GO_0031410 . obo:GO_0044841 obo:IAO_0000115 "The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-25T12:02:05Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0044841" ; a owl:Class ; rdfs:label "gut granule membrane" ; rdfs:subClassOf obo:GO_0030659, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044840 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031090 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044840 ] ) ] . obo:GO_0044842 obo:IAO_0000115 "The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-25T12:02:32Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0044842" ; a owl:Class ; rdfs:label "gut granule lumen" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044840 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043233 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044840 ] ) ] . obo:GO_0044843 obo:IAO_0000115 "The cell cycle process by which a cell in G1 phase commits to S phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-25T16:33:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044843" ; a owl:Class ; rdfs:label "cell cycle G1/S phase transition" ; rdfs:subClassOf obo:GO_0044770 . obo:GO_0044848 obo:IAO_0000115 "A distinct period or stage in a biological process or cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-07-16T13:12:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044848" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase." ; rdfs:label "biological phase" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0048511, obo:GO_0050896, obo:GO_0051179, obo:GO_0071840 . obo:GO_0044877 obo:IAO_0000115 "Binding to a macromolecular complex." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-12-16T11:38:58Z" ; oboInOwl:hasAlternativeId "GO:0032403" ; oboInOwl:hasExactSynonym "protein complex binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "macromolecular complex binding" ; oboInOwl:id "GO:0044877" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "protein-containing complex binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0032991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0032991 ] ) ] . obo:GO_0045026 obo:IAO_0000115 "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell." ; oboInOwl:hasAlternativeId "GO:0006947" ; oboInOwl:hasBroadSynonym "cell fusion", "cell-cell fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045026" ; a owl:Class ; rdfs:label "plasma membrane fusion" ; rdfs:subClassOf obo:GO_0007009, obo:GO_0061025, [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0045055 obo:IAO_0000115 "A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand." ; oboInOwl:hasExactSynonym "regulated secretory pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045055" ; a owl:Class ; rdfs:label "regulated exocytosis" ; rdfs:subClassOf obo:GO_0006887 . obo:GO_0045087 obo:IAO_0000115 "Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." ; obo:RO_0002161 obo:NCBITaxon_Union_0000023 ; oboInOwl:hasAlternativeId "GO:0002226" ; oboInOwl:hasDbXref "Wikipedia:Innate_immune_system" ; oboInOwl:hasExactSynonym "innate immunity", "nonspecific immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045087" ; a owl:Class ; rdfs:label "innate immune response" ; rdfs:subClassOf obo:GO_0006955, obo:GO_0098542 . obo:GO_0045088 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045088" ; a owl:Class ; rdfs:label "regulation of innate immune response" ; rdfs:subClassOf obo:GO_0002831, obo:GO_0031347, obo:GO_0032101, obo:GO_0050776, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045087 ] ) ] . obo:GO_0045089 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." ; oboInOwl:hasExactSynonym "up regulation of innate immune response", "up-regulation of innate immune response", "upregulation of innate immune response" ; oboInOwl:hasNarrowSynonym "stimulation of innate immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045089" ; a owl:Class ; rdfs:label "positive regulation of innate immune response" ; rdfs:subClassOf obo:GO_0002833, obo:GO_0031349, obo:GO_0032103, obo:GO_0045088, obo:GO_0050778, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045087 ] ) ] . obo:GO_0045120 obo:IAO_0000115 "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." ; oboInOwl:hasDbXref "Wikipedia:Pronucleus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0045120" ; a owl:Class ; rdfs:label "pronucleus" ; rdfs:subClassOf obo:GO_0005634, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0045132 obo:IAO_0000115 "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045132" ; a owl:Class ; rdfs:label "meiotic chromosome segregation" ; rdfs:subClassOf obo:GO_0098813, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098813 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0045137 obo:IAO_0000115 "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045137" ; a owl:Class ; rdfs:label "development of primary sexual characteristics" ; rdfs:subClassOf obo:GO_0003006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007548 ] . obo:GO_0045143 obo:IAO_0000115 "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." ; oboInOwl:hasAlternativeId "GO:0007061" ; oboInOwl:hasExactSynonym "meiosis I, chromosome segregation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045143" ; a owl:Class ; rdfs:label "homologous chromosome segregation" ; rdfs:subClassOf obo:GO_0045132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098813 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0045144 obo:IAO_0000115 "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle." ; oboInOwl:hasExactSynonym "meiosis II, chromosome segregation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045144" ; a owl:Class ; rdfs:label "meiotic sister chromatid segregation" ; rdfs:subClassOf obo:GO_0000819, obo:GO_0045132, obo:GO_0070192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007135 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000819 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007135 ] ) ] . obo:GO_0045161 obo:IAO_0000115 "The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045161" ; a owl:Class ; rdfs:label "neuronal ion channel clustering" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042551 ] . obo:GO_0045165 obo:IAO_0000115 "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045165" ; a owl:Class ; rdfs:comment "Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created." ; rdfs:label "cell fate commitment" ; rdfs:subClassOf obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030154 ] . obo:GO_0045168 obo:IAO_0000115 "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." ; oboInOwl:hasExactSynonym "cell fate commitment, cell-cell signaling", "cell fate commitment, cell-cell signalling", "cell-cell signaling during in cell fate commitment", "cell-cell signaling resulting in cell fate commitment", "cell-cell signalling during cell fate commitment", "cell-cell signalling resulting in cell fate commitment" ; oboInOwl:hasNarrowSynonym "cell-cell signalling involved in cell fate specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045168" ; a owl:Class ; rdfs:label "cell-cell signaling involved in cell fate commitment" ; rdfs:subClassOf obo:GO_0007267, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045165 ] ) ] . obo:GO_0045184 obo:IAO_0000115 "The directed movement of a protein to a specific location." ; oboInOwl:hasExactSynonym "establishment of protein localisation", "protein positioning", "protein recruitment" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045184" ; a owl:Class ; rdfs:label "establishment of protein localization" ; rdfs:subClassOf obo:GO_0008104, obo:GO_0051234 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051234 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36080 ] ) ] . obo:GO_0045185 obo:IAO_0000115 "Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away." ; oboInOwl:hasNarrowSynonym "active protein retrieval", "protein retention", "protein sequestering" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "maintenance of protein localization" ; oboInOwl:id "GO:0045185" ; a owl:Class ; rdfs:label "maintenance of protein location" ; rdfs:subClassOf obo:GO_0051235, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008104 ] . obo:GO_0045196 obo:IAO_0000115 "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." ; oboInOwl:hasAlternativeId "GO:0043339", "GO:0043342" ; oboInOwl:hasExactSynonym "establishment and/or maintenance of neuroblast cell polarity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045196" ; a owl:Class ; rdfs:label "establishment or maintenance of neuroblast polarity" ; rdfs:subClassOf obo:GO_0007163, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055059 ] . obo:GO_0045200 obo:IAO_0000115 "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system." ; oboInOwl:hasAlternativeId "GO:0043340", "GO:0043343" ; oboInOwl:hasExactSynonym "establishment of neuroblast cell polarity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045200" ; a owl:Class ; rdfs:label "establishment of neuroblast polarity" ; rdfs:subClassOf obo:GO_0030010, obo:GO_0045196, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000031 ] ) ] . obo:GO_0045202 obo:IAO_0000115 "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." ; oboInOwl:hasDbXref "NIF_Subcellular:sao914572699", "Wikipedia:Chemical_synapse" ; oboInOwl:hasExactSynonym "synaptic junction" ; oboInOwl:hasNarrowSynonym "mixed synapse" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "electrotonic synapse" ; oboInOwl:id "GO:0045202" ; oboInOwl:inSubset go:goslim_agr, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir, go:goslim_synapse ; a owl:Class ; rdfs:label "synapse" ; rdfs:subClassOf obo:GO_0030054, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0045214 obo:IAO_0000115 "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ; oboInOwl:hasAlternativeId "GO:0006938" ; oboInOwl:hasExactSynonym "sarcomere alignment", "sarcomere organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045214" ; a owl:Class ; rdfs:label "sarcomere organization" ; rdfs:subClassOf obo:GO_0031032, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030239 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0030017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0030017 ] ) ] . obo:GO_0045216 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells." ; oboInOwl:hasExactSynonym "cell-cell junction assembly and maintenance", "cell-cell junction organisation", "intercellular junction assembly and maintenance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell-cell junction biogenesis" ; oboInOwl:id "GO:0045216" ; a owl:Class ; rdfs:label "cell-cell junction organization" ; rdfs:subClassOf obo:GO_0034330, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0034330 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005911 ] ) ] . obo:GO_0045222 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions." ; oboInOwl:hasExactSynonym "CD4 anabolism", "CD4 biosynthesis", "CD4 formation", "CD4 synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045222" ; a owl:Class ; rdfs:label "CD4 biosynthetic process" ; rdfs:subClassOf obo:GO_0009101, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:PR_000001004 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:PR_000001004 ] ) ] . obo:GO_0045223 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." ; oboInOwl:hasExactSynonym "regulation of CD4 anabolism", "regulation of CD4 biosynthesis", "regulation of CD4 biosynthetic process", "regulation of CD4 formation", "regulation of CD4 synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045223" ; a owl:Class ; rdfs:label "regulation of CD4 production" ; rdfs:subClassOf obo:GO_0010559, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045222 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045222 ] ) ] . obo:GO_0045224 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." ; oboInOwl:hasExactSynonym "positive regulation of CD4 anabolism", "positive regulation of CD4 biosynthesis", "positive regulation of CD4 biosynthetic process", "positive regulation of CD4 formation", "positive regulation of CD4 synthesis", "up regulation of CD4 biosynthetic process", "up-regulation of CD4 biosynthetic process", "upregulation of CD4 biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of CD4 biosynthetic process", "stimulation of CD4 biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045224" ; a owl:Class ; rdfs:label "positive regulation of CD4 production" ; rdfs:subClassOf obo:GO_0010560, obo:GO_0045223, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045222 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045222 ] ) ] . obo:GO_0045225 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4." ; oboInOwl:hasExactSynonym "down regulation of CD4 biosynthetic process", "down-regulation of CD4 biosynthetic process", "downregulation of CD4 biosynthetic process", "negative regulation of CD4 anabolism", "negative regulation of CD4 biosynthesis", "negative regulation of CD4 biosynthetic process", "negative regulation of CD4 formation", "negative regulation of CD4 synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of CD4 biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045225" ; a owl:Class ; rdfs:label "negative regulation of CD4 production" ; rdfs:subClassOf obo:GO_0010561, obo:GO_0045223, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045222 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045222 ] ) ] . obo:GO_0045229 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell." ; oboInOwl:hasExactSynonym "external encapsulating structure organisation", "external encapsulating structure organization and biogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045229" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "external encapsulating structure organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0030312 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0030312 ] ) ] . obo:GO_0045296 obo:IAO_0000115 "Binding to cadherin, a type I membrane protein involved in cell adhesion." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0045296" ; a owl:Class ; rdfs:label "cadherin binding" ; rdfs:subClassOf obo:GO_0050839, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000001327 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:PR_000001327 ] ) ] . obo:GO_0045321 obo:IAO_0000115 "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor." ; oboInOwl:hasDbXref "Wikipedia:Immunologic_activation" ; oboInOwl:hasExactSynonym "immune cell activation", "leucocyte activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045321" ; a owl:Class ; rdfs:label "leukocyte activation" ; rdfs:subClassOf obo:GO_0001775, obo:GO_0002376, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000738 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0045444 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat." ; oboInOwl:hasExactSynonym "adipocyte cell differentiation", "adipocyte differentiation", "adipose cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "adipogenesis" ; oboInOwl:id "GO:0045444" ; a owl:Class ; rdfs:label "fat cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000136 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000136 ] ) ] . obo:GO_0045445 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers." ; oboInOwl:hasExactSynonym "myoblast cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045445" ; a owl:Class ; rdfs:label "myoblast differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061061 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000056 ] ) ] . obo:GO_0045446 obo:IAO_0000115 "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045446" ; a owl:Class ; rdfs:label "endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0030855, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003158 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000115 ] ) ] . obo:GO_0045495 obo:IAO_0000115 "Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasExactSynonym "polar plasm" ; oboInOwl:hasNarrowSynonym "germ plasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0045495" ; a owl:Class ; rdfs:label "pole plasm" ; rdfs:subClassOf obo:GO_0005737 . obo:GO_0045580 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of T cell differentiation." ; oboInOwl:hasExactSynonym "regulation of T lymphocyte differentiation", "regulation of T-cell differentiation", "regulation of T-lymphocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of T cell development" ; oboInOwl:id "GO:0045580" ; a owl:Class ; rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "regulation of T cell differentiation" ; rdfs:subClassOf obo:GO_0045619, obo:GO_0050863, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030217 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030217 ] ) ] . obo:GO_0045581 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of T cell differentiation", "down-regulation of T cell differentiation", "downregulation of T cell differentiation", "negative regulation of T lymphocyte differentiation", "negative regulation of T-cell differentiation", "negative regulation of T-lymphocyte differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of T cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of T cell development" ; oboInOwl:id "GO:0045581" ; a owl:Class ; rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "negative regulation of T cell differentiation" ; rdfs:subClassOf obo:GO_0045580, obo:GO_0045620, obo:GO_0050868, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030217 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030217 ] ) ] . obo:GO_0045582 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of T cell differentiation." ; oboInOwl:hasExactSynonym "positive regulation of T lymphocyte differentiation", "positive regulation of T-cell differentiation", "positive regulation of T-lymphocyte differentiation", "up regulation of T cell differentiation", "up-regulation of T cell differentiation", "upregulation of T cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of T cell differentiation", "stimulation of T cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of T cell development" ; oboInOwl:id "GO:0045582" ; a owl:Class ; rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "positive regulation of T cell differentiation" ; rdfs:subClassOf obo:GO_0045580, obo:GO_0045621, obo:GO_0050870, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030217 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030217 ] ) ] . obo:GO_0045595 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045595" ; a owl:Class ; rdfs:label "regulation of cell differentiation" ; rdfs:subClassOf obo:GO_0050793, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030154 ] ) ] . obo:GO_0045596 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of cell differentiation", "down-regulation of cell differentiation", "downregulation of cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045596" ; a owl:Class ; rdfs:label "negative regulation of cell differentiation" ; rdfs:subClassOf obo:GO_0045595, obo:GO_0048523, obo:GO_0051093, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030154 ] ) ] . obo:GO_0045597 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of cell differentiation", "up-regulation of cell differentiation", "upregulation of cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of cell differentiation", "stimulation of cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045597" ; a owl:Class ; rdfs:label "positive regulation of cell differentiation" ; rdfs:subClassOf obo:GO_0045595, obo:GO_0048522, obo:GO_0051094, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030154 ] ) ] . obo:GO_0045598 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of adipocyte differentiation." ; oboInOwl:hasExactSynonym "regulation of adipocyte cell differentiation", "regulation of adipocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045598" ; a owl:Class ; rdfs:label "regulation of fat cell differentiation" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045444 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045444 ] ) ] . obo:GO_0045599 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation." ; oboInOwl:hasExactSynonym "down regulation of fat cell differentiation", "down-regulation of fat cell differentiation", "downregulation of fat cell differentiation", "negative regulation of adipocyte cell differentiation", "negative regulation of adipocyte differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of fat cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045599" ; a owl:Class ; rdfs:label "negative regulation of fat cell differentiation" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0045598, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045444 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045444 ] ) ] . obo:GO_0045600 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation." ; oboInOwl:hasExactSynonym "positive regulation of adipocyte cell differentiation", "positive regulation of adipocyte differentiation", "up regulation of fat cell differentiation", "up-regulation of fat cell differentiation", "upregulation of fat cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of fat cell differentiation", "stimulation of fat cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045600" ; a owl:Class ; rdfs:label "positive regulation of fat cell differentiation" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0045598, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045444 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045444 ] ) ] . obo:GO_0045601 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of endothelial cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045601" ; a owl:Class ; rdfs:label "regulation of endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0030856, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045446 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045446 ] ) ] . obo:GO_0045602 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of endothelial cell differentiation", "down-regulation of endothelial cell differentiation", "downregulation of endothelial cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of endothelial cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045602" ; a owl:Class ; rdfs:label "negative regulation of endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0030857, obo:GO_0045601, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045446 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045446 ] ) ] . obo:GO_0045603 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of endothelial cell differentiation", "up-regulation of endothelial cell differentiation", "upregulation of endothelial cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of endothelial cell differentiation", "stimulation of endothelial cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045603" ; a owl:Class ; rdfs:label "positive regulation of endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0030858, obo:GO_0045601, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045446 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045446 ] ) ] . obo:GO_0045604 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of epidermal cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of hypodermal cell differentiation" ; oboInOwl:id "GO:0045604" ; a owl:Class ; rdfs:label "regulation of epidermal cell differentiation" ; rdfs:subClassOf obo:GO_0030856, obo:GO_0045682, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009913 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009913 ] ) ] . obo:GO_0045605 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of epidermal cell differentiation", "down-regulation of epidermal cell differentiation", "downregulation of epidermal cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of epidermal cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of hypodermal cell differentiation" ; oboInOwl:id "GO:0045605" ; a owl:Class ; rdfs:label "negative regulation of epidermal cell differentiation" ; rdfs:subClassOf obo:GO_0030857, obo:GO_0045604, obo:GO_0045683, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009913 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009913 ] ) ] . obo:GO_0045606 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of epidermal cell differentiation", "up-regulation of epidermal cell differentiation", "upregulation of epidermal cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of epidermal cell differentiation", "stimulation of epidermal cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of hypodermal cell differentiation" ; oboInOwl:id "GO:0045606" ; a owl:Class ; rdfs:label "positive regulation of epidermal cell differentiation" ; rdfs:subClassOf obo:GO_0030858, obo:GO_0045604, obo:GO_0045684, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009913 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009913 ] ) ] . obo:GO_0045619 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of lymphocyte differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of lymphocyte development" ; oboInOwl:id "GO:0045619" ; a owl:Class ; rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "regulation of lymphocyte differentiation" ; rdfs:subClassOf obo:GO_0051249, obo:GO_1902105, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030098 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030098 ] ) ] . obo:GO_0045620 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation." ; oboInOwl:hasExactSynonym "down regulation of lymphocyte differentiation", "down-regulation of lymphocyte differentiation", "downregulation of lymphocyte differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of lymphocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of lymphocyte development" ; oboInOwl:id "GO:0045620" ; a owl:Class ; rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "negative regulation of lymphocyte differentiation" ; rdfs:subClassOf obo:GO_0045619, obo:GO_0051250, obo:GO_1902106, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030098 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030098 ] ) ] . obo:GO_0045621 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation." ; oboInOwl:hasExactSynonym "up regulation of lymphocyte differentiation", "up-regulation of lymphocyte differentiation", "upregulation of lymphocyte differentiation" ; oboInOwl:hasNarrowSynonym "activation of lymphocyte differentiation", "stimulation of lymphocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of lymphocyte development" ; oboInOwl:id "GO:0045621" ; a owl:Class ; rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "positive regulation of lymphocyte differentiation" ; rdfs:subClassOf obo:GO_0045619, obo:GO_0051251, obo:GO_1902107, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030098 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030098 ] ) ] . obo:GO_0045637 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of myeloid cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045637" ; a owl:Class ; rdfs:label "regulation of myeloid cell differentiation" ; rdfs:subClassOf obo:GO_1903706, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030099 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030099 ] ) ] . obo:GO_0045638 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of myeloid cell differentiation", "down-regulation of myeloid cell differentiation", "downregulation of myeloid cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of myeloid cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045638" ; a owl:Class ; rdfs:label "negative regulation of myeloid cell differentiation" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0045637, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030099 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030099 ] ) ] . obo:GO_0045639 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of myeloid cell differentiation", "up-regulation of myeloid cell differentiation", "upregulation of myeloid cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of myeloid cell differentiation", "stimulation of myeloid cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045639" ; a owl:Class ; rdfs:label "positive regulation of myeloid cell differentiation" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0045637, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030099 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030099 ] ) ] . obo:GO_0045646 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of erythrocyte differentiation." ; oboInOwl:hasExactSynonym "regulation of RBC differentiation", "regulation of red blood cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045646" ; a owl:Class ; rdfs:label "regulation of erythrocyte differentiation" ; rdfs:subClassOf obo:GO_0045637, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030218 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030218 ] ) ] . obo:GO_0045647 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation." ; oboInOwl:hasExactSynonym "down regulation of erythrocyte differentiation", "down-regulation of erythrocyte differentiation", "downregulation of erythrocyte differentiation", "negative regulation of RBC differentiation", "negative regulation of red blood cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of erythrocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045647" ; a owl:Class ; rdfs:label "negative regulation of erythrocyte differentiation" ; rdfs:subClassOf obo:GO_0045638, obo:GO_0045646, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030218 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030218 ] ) ] . obo:GO_0045648 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation." ; oboInOwl:hasExactSynonym "positive regulation of RBC differentiation", "positive regulation of red blood cell differentiation", "up regulation of erythrocyte differentiation", "up-regulation of erythrocyte differentiation", "upregulation of erythrocyte differentiation" ; oboInOwl:hasNarrowSynonym "activation of erythrocyte differentiation", "stimulation of erythrocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045648" ; a owl:Class ; rdfs:label "positive regulation of erythrocyte differentiation" ; rdfs:subClassOf obo:GO_0045639, obo:GO_0045646, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030218 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030218 ] ) ] . obo:GO_0045652 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045652" ; a owl:Class ; rdfs:label "regulation of megakaryocyte differentiation" ; rdfs:subClassOf obo:GO_0045637, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030219 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030219 ] ) ] . obo:GO_0045653 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation." ; oboInOwl:hasExactSynonym "down regulation of megakaryocyte differentiation", "down-regulation of megakaryocyte differentiation", "downregulation of megakaryocyte differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of megakaryocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045653" ; a owl:Class ; rdfs:label "negative regulation of megakaryocyte differentiation" ; rdfs:subClassOf obo:GO_0045638, obo:GO_0045652, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030219 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030219 ] ) ] . obo:GO_0045654 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation." ; oboInOwl:hasExactSynonym "up regulation of megakaryocyte differentiation", "up-regulation of megakaryocyte differentiation", "upregulation of megakaryocyte differentiation" ; oboInOwl:hasNarrowSynonym "activation of megakaryocyte differentiation", "stimulation of megakaryocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045654" ; a owl:Class ; rdfs:label "positive regulation of megakaryocyte differentiation" ; rdfs:subClassOf obo:GO_0045639, obo:GO_0045652, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030219 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030219 ] ) ] . obo:GO_0045661 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045661" ; a owl:Class ; rdfs:label "regulation of myoblast differentiation" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045445 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045445 ] ) ] . obo:GO_0045662 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ; oboInOwl:hasExactSynonym "down regulation of myoblast differentiation", "down-regulation of myoblast differentiation", "downregulation of myoblast differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of myoblast differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045662" ; a owl:Class ; rdfs:label "negative regulation of myoblast differentiation" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0045661, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045445 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045445 ] ) ] . obo:GO_0045663 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ; oboInOwl:hasExactSynonym "up regulation of myoblast differentiation", "up-regulation of myoblast differentiation", "upregulation of myoblast differentiation" ; oboInOwl:hasNarrowSynonym "activation of myoblast differentiation", "stimulation of myoblast differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045663" ; a owl:Class ; rdfs:label "positive regulation of myoblast differentiation" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0045661, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045445 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045445 ] ) ] . obo:GO_0045664 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of neuron differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045664" ; a owl:Class ; rdfs:label "regulation of neuron differentiation" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030182 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030182 ] ) ] . obo:GO_0045665 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." ; oboInOwl:hasExactSynonym "down regulation of neuron differentiation", "down-regulation of neuron differentiation", "downregulation of neuron differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of neuron differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045665" ; a owl:Class ; rdfs:label "negative regulation of neuron differentiation" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0045664, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030182 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030182 ] ) ] . obo:GO_0045666 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of neuron differentiation." ; oboInOwl:hasExactSynonym "up regulation of neuron differentiation", "up-regulation of neuron differentiation", "upregulation of neuron differentiation" ; oboInOwl:hasNarrowSynonym "activation of neuron differentiation", "stimulation of neuron differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045666" ; a owl:Class ; rdfs:label "positive regulation of neuron differentiation" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0045664, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030182 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030182 ] ) ] . obo:GO_0045682 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of epidermis development." ; oboInOwl:hasExactSynonym "regulation of epidermal development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of hypodermis development" ; oboInOwl:id "GO:0045682" ; a owl:Class ; rdfs:label "regulation of epidermis development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008544 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008544 ] ) ] . obo:GO_0045683 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development." ; oboInOwl:hasExactSynonym "down regulation of epidermis development", "down-regulation of epidermis development", "downregulation of epidermis development", "negative regulation of epidermal development" ; oboInOwl:hasNarrowSynonym "inhibition of epidermis development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of hypodermis development" ; oboInOwl:id "GO:0045683" ; a owl:Class ; rdfs:label "negative regulation of epidermis development" ; rdfs:subClassOf obo:GO_0045682, obo:GO_0051093, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008544 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008544 ] ) ] . obo:GO_0045684 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of epidermis development." ; oboInOwl:hasExactSynonym "positive regulation of epidermal development", "up regulation of epidermis development", "up-regulation of epidermis development", "upregulation of epidermis development" ; oboInOwl:hasNarrowSynonym "activation of epidermis development", "stimulation of epidermis development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of hypodermis development" ; oboInOwl:id "GO:0045684" ; a owl:Class ; rdfs:label "positive regulation of epidermis development" ; rdfs:subClassOf obo:GO_0045682, obo:GO_0051094, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008544 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008544 ] ) ] . obo:GO_0045685 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of glia cell differentiation." ; oboInOwl:hasExactSynonym "regulation of glia cell differentiation", "regulation of neuroglia differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045685" ; a owl:Class ; rdfs:label "regulation of glial cell differentiation" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010001 ] ) ] . obo:GO_0045686 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of glial cell differentiation", "down-regulation of glial cell differentiation", "downregulation of glial cell differentiation", "negative regulation of glia cell differentiation", "negative regulation of neuroglia differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of glial cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045686" ; a owl:Class ; rdfs:label "negative regulation of glial cell differentiation" ; rdfs:subClassOf obo:GO_0014014, obo:GO_0045685, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010001 ] ) ] . obo:GO_0045687 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of glia cell differentiation." ; oboInOwl:hasExactSynonym "positive regulation of glia cell differentiation", "positive regulation of neuroglia differentiation", "up regulation of glial cell differentiation", "up-regulation of glial cell differentiation", "upregulation of glial cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of glial cell differentiation", "stimulation of glial cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045687" ; a owl:Class ; rdfs:label "positive regulation of glial cell differentiation" ; rdfs:subClassOf obo:GO_0014015, obo:GO_0045685, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010001 ] ) ] . obo:GO_0045700 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045700" ; a owl:Class ; rdfs:label "regulation of spermatid nuclear differentiation" ; rdfs:subClassOf obo:GO_0051239, obo:GO_1903353, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007289 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007289 ] ) ] . obo:GO_0045701 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation." ; oboInOwl:hasExactSynonym "down regulation of spermatid nuclear differentiation", "down-regulation of spermatid nuclear differentiation", "downregulation of spermatid nuclear differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of spermatid nuclear differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045701" ; a owl:Class ; rdfs:label "negative regulation of spermatid nuclear differentiation" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0045596, obo:GO_0045700, obo:GO_0051241, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007289 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007289 ] ) ] . obo:GO_0045702 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." ; oboInOwl:hasExactSynonym "up regulation of spermatid nuclear differentiation", "up-regulation of spermatid nuclear differentiation", "upregulation of spermatid nuclear differentiation" ; oboInOwl:hasNarrowSynonym "activation of spermatid nuclear differentiation", "stimulation of spermatid nuclear differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045702" ; a owl:Class ; rdfs:label "positive regulation of spermatid nuclear differentiation" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0045597, obo:GO_0045700, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007289 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007289 ] ) ] . obo:GO_0045719 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." ; oboInOwl:hasExactSynonym "down regulation of glycogen biosynthetic process", "down-regulation of glycogen biosynthetic process", "downregulation of glycogen biosynthetic process", "negative regulation of glycogen anabolism", "negative regulation of glycogen biosynthesis", "negative regulation of glycogen formation", "negative regulation of glycogen synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of glycogen biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045719" ; a owl:Class ; rdfs:label "negative regulation of glycogen biosynthetic process" ; rdfs:subClassOf obo:GO_0005979, obo:GO_0010558, obo:GO_0070874, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005978 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005978 ] ) ] . obo:GO_0045721 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis." ; oboInOwl:hasExactSynonym "down regulation of gluconeogenesis", "down-regulation of gluconeogenesis", "downregulation of gluconeogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of gluconeogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045721" ; a owl:Class ; rdfs:label "negative regulation of gluconeogenesis" ; rdfs:subClassOf obo:GO_0006111, obo:GO_0031327, obo:GO_0045912, obo:GO_0062014, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006094 ] ) ] . obo:GO_0045722 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of gluconeogenesis." ; oboInOwl:hasExactSynonym "up regulation of gluconeogenesis", "up-regulation of gluconeogenesis", "upregulation of gluconeogenesis" ; oboInOwl:hasNarrowSynonym "activation of gluconeogenesis", "stimulation of gluconeogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045722" ; a owl:Class ; rdfs:label "positive regulation of gluconeogenesis" ; rdfs:subClassOf obo:GO_0006111, obo:GO_0010907, obo:GO_0031328, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006094 ] ) ] . obo:GO_0045724 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the formation of a cilium." ; oboInOwl:hasBroadSynonym "positive regulation of flagellum assembly" ; oboInOwl:hasExactSynonym "up regulation of cilium assembly", "up-regulation of cilium assembly", "upregulation of cilium assembly" ; oboInOwl:hasNarrowSynonym "activation of cilium assembly", "stimulation of cilium assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of flagellum biogenesis" ; oboInOwl:id "GO:0045724" ; a owl:Class ; rdfs:label "positive regulation of cilium assembly" ; rdfs:subClassOf obo:GO_0120034, obo:GO_1902017, obo:GO_1902117, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060271 ] ) ] . obo:GO_0045725 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen." ; oboInOwl:hasExactSynonym "positive regulation of glycogen anabolism", "positive regulation of glycogen biosynthesis", "positive regulation of glycogen formation", "positive regulation of glycogen synthesis", "up regulation of glycogen biosynthetic process", "up-regulation of glycogen biosynthetic process", "upregulation of glycogen biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of glycogen biosynthetic process", "stimulation of glycogen biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045725" ; a owl:Class ; rdfs:label "positive regulation of glycogen biosynthetic process" ; rdfs:subClassOf obo:GO_0005979, obo:GO_0010557, obo:GO_0031328, obo:GO_0070875, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005978 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005978 ] ) ] . obo:GO_0045727 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ; oboInOwl:hasAlternativeId "GO:0045946" ; oboInOwl:hasExactSynonym "positive regulation of protein anabolism", "positive regulation of protein biosynthesis", "positive regulation of protein biosynthetic process", "positive regulation of protein formation", "positive regulation of protein synthesis", "up regulation of protein biosynthetic process", "up-regulation of protein biosynthetic process", "upregulation of protein biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of protein biosynthetic process", "stimulation of protein biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045727" ; a owl:Class ; rdfs:label "positive regulation of translation" ; rdfs:subClassOf obo:GO_0006417, obo:GO_0010557, obo:GO_0010628, obo:GO_0031328, obo:GO_0034250, obo:GO_0051247, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0045732 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:1903364", "GO:2000600" ; oboInOwl:hasExactSynonym "positive regulation of cellular protein breakdown", "positive regulation of cellular protein catabolic process", "positive regulation of cellular protein catabolism", "positive regulation of cellular protein degradation", "positive regulation of protein breakdown", "positive regulation of protein catabolism", "positive regulation of protein degradation", "up regulation of cellular protein breakdown", "up regulation of cellular protein catabolic process", "up regulation of cellular protein catabolism", "up regulation of cellular protein degradation", "up regulation of protein catabolic process", "up-regulation of cellular protein breakdown", "up-regulation of cellular protein catabolic process", "up-regulation of cellular protein catabolism", "up-regulation of cellular protein degradation", "up-regulation of protein catabolic process", "upregulation of cellular protein breakdown", "upregulation of cellular protein catabolic process", "upregulation of cellular protein catabolism", "upregulation of cellular protein degradation", "upregulation of protein catabolic process" ; oboInOwl:hasNarrowSynonym "activation of cellular protein breakdown", "activation of cellular protein catabolic process", "activation of cellular protein catabolism", "activation of cellular protein degradation", "activation of protein catabolic process", "positive regulation of cyclin breakdown", "positive regulation of cyclin catabolic process", "positive regulation of cyclin catabolism", "positive regulation of cyclin degradation", "positive regulation of degradation of cyclin", "stimulation of protein catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045732" ; a owl:Class ; rdfs:label "positive regulation of protein catabolic process" ; rdfs:subClassOf obo:GO_0009896, obo:GO_0042176, obo:GO_0051247, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030163 ] ) ] . obo:GO_0045733 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." ; oboInOwl:hasAlternativeId "GO:0019663" ; oboInOwl:hasExactSynonym "acetate breakdown", "acetate catabolism", "acetate degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "homoacetate catabolic process" ; oboInOwl:id "GO:0045733" ; a owl:Class ; rdfs:label "acetate catabolic process" ; rdfs:subClassOf obo:GO_0006083, obo:GO_0072329, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_30089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_30089 ] ) ] . obo:GO_0045734 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid." ; oboInOwl:hasExactSynonym "regulation of acetate breakdown", "regulation of acetate catabolism", "regulation of acetate degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045734" ; a owl:Class ; rdfs:label "regulation of acetate catabolic process" ; rdfs:subClassOf obo:GO_0010565, obo:GO_0031329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045733 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045733 ] ) ] . obo:GO_0045740 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of DNA replication." ; oboInOwl:hasExactSynonym "up regulation of DNA replication", "up-regulation of DNA replication", "upregulation of DNA replication" ; oboInOwl:hasNarrowSynonym "activation of DNA replication", "stimulation of DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045740" ; a owl:Class ; rdfs:label "positive regulation of DNA replication" ; rdfs:subClassOf obo:GO_0006275, obo:GO_0051054, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006260 ] ) ] . obo:GO_0045753 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." ; oboInOwl:hasExactSynonym "down regulation of acetate catabolic process", "down-regulation of acetate catabolic process", "downregulation of acetate catabolic process", "negative regulation of acetate breakdown", "negative regulation of acetate catabolism", "negative regulation of acetate degradation" ; oboInOwl:hasNarrowSynonym "inhibition of acetate catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045753" ; a owl:Class ; rdfs:label "negative regulation of acetate catabolic process" ; rdfs:subClassOf obo:GO_0031330, obo:GO_0045734, obo:GO_0062014, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045733 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045733 ] ) ] . obo:GO_0045754 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate." ; oboInOwl:hasExactSynonym "positive regulation of acetate breakdown", "positive regulation of acetate catabolism", "positive regulation of acetate degradation", "up regulation of acetate catabolic process", "up-regulation of acetate catabolic process", "upregulation of acetate catabolic process" ; oboInOwl:hasNarrowSynonym "activation of acetate catabolic process", "stimulation of acetate catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045754" ; a owl:Class ; rdfs:label "positive regulation of acetate catabolic process" ; rdfs:subClassOf obo:GO_0031331, obo:GO_0045734, obo:GO_0062013, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045733 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045733 ] ) ] . obo:GO_0045759 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ; oboInOwl:hasExactSynonym "down regulation of action potential", "down-regulation of action potential", "downregulation of action potential" ; oboInOwl:hasNarrowSynonym "inhibition of action potential" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045759" ; a owl:Class ; rdfs:label "negative regulation of action potential" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0098900, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001508 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001508 ] ) ] . obo:GO_0045760 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ; oboInOwl:hasExactSynonym "up regulation of action potential", "up-regulation of action potential", "upregulation of action potential" ; oboInOwl:hasNarrowSynonym "activation of action potential", "stimulation of action potential" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045760" ; a owl:Class ; rdfs:label "positive regulation of action potential" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0098900, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001508 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001508 ] ) ] . obo:GO_0045763 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid." ; oboInOwl:hasExactSynonym "down regulation of amino acid metabolic process", "down-regulation of amino acid metabolic process", "downregulation of amino acid metabolic process", "negative regulation of amino acid metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of amino acid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045763" ; a owl:Class ; rdfs:label "negative regulation of cellular amino acid metabolic process" ; rdfs:subClassOf obo:GO_0006521, obo:GO_0031324, obo:GO_0033239, obo:GO_0062014, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006520 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006520 ] ) ] . obo:GO_0045764 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid." ; oboInOwl:hasExactSynonym "positive regulation of amino acid metabolism", "positive regulation of cellular amino acid metabolic process", "up regulation of amino acid metabolic process", "up-regulation of amino acid metabolic process", "upregulation of amino acid metabolic process" ; oboInOwl:hasNarrowSynonym "activation of amino acid metabolic process", "stimulation of amino acid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045764" ; a owl:Class ; rdfs:label "positive regulation of amino acid metabolic process" ; rdfs:subClassOf obo:GO_0006521, obo:GO_0031325, obo:GO_0033240, obo:GO_0062013, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006520 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006520 ] ) ] . obo:GO_0045765 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of angiogenesis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045765" ; a owl:Class ; rdfs:label "regulation of angiogenesis" ; rdfs:subClassOf obo:GO_0022603, obo:GO_1901342, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001525 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001525 ] ) ] . obo:GO_0045766 obo:IAO_0000115 "Any process that activates or increases angiogenesis." ; oboInOwl:hasExactSynonym "up regulation of angiogenesis", "up-regulation of angiogenesis", "upregulation of angiogenesis" ; oboInOwl:hasNarrowSynonym "activation of angiogenesis", "stimulation of angiogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045766" ; a owl:Class ; rdfs:label "positive regulation of angiogenesis" ; rdfs:subClassOf obo:GO_0045765, obo:GO_1904018, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001525 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001525 ] ) ] . obo:GO_0045769 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." ; oboInOwl:hasExactSynonym "down regulation of asymmetric cell division", "down-regulation of asymmetric cell division", "downregulation of asymmetric cell division" ; oboInOwl:hasNarrowSynonym "inhibition of asymmetric cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045769" ; a owl:Class ; rdfs:label "negative regulation of asymmetric cell division" ; rdfs:subClassOf obo:GO_0009786, obo:GO_0051782, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008356 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008356 ] ) ] . obo:GO_0045770 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." ; oboInOwl:hasExactSynonym "up regulation of asymmetric cell division", "up-regulation of asymmetric cell division", "upregulation of asymmetric cell division" ; oboInOwl:hasNarrowSynonym "activation of asymmetric cell division", "stimulation of asymmetric cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045770" ; a owl:Class ; rdfs:label "positive regulation of asymmetric cell division" ; rdfs:subClassOf obo:GO_0009786, obo:GO_0051781, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008356 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008356 ] ) ] . obo:GO_0045773 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of axon extension." ; oboInOwl:hasExactSynonym "up regulation of axon extension", "up-regulation of axon extension", "upregulation of axon extension" ; oboInOwl:hasNarrowSynonym "activation of axon extension", "stimulation of axon extension" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045773" ; a owl:Class ; rdfs:label "positive regulation of axon extension" ; rdfs:subClassOf obo:GO_0030307, obo:GO_0030516, obo:GO_0048639, obo:GO_0050772, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048675 ] ) ] . obo:GO_0045778 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance." ; oboInOwl:hasExactSynonym "positive regulation of bone biosynthesis", "positive regulation of bone formation", "up regulation of ossification", "up-regulation of ossification", "upregulation of ossification" ; oboInOwl:hasNarrowSynonym "activation of ossification", "stimulation of ossification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045778" ; a owl:Class ; rdfs:label "positive regulation of ossification" ; rdfs:subClassOf obo:GO_0030278, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001503 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001503 ] ) ] . obo:GO_0045785 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell adhesion." ; oboInOwl:hasExactSynonym "up regulation of cell adhesion", "up-regulation of cell adhesion", "upregulation of cell adhesion" ; oboInOwl:hasNarrowSynonym "activation of cell adhesion", "stimulation of cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045785" ; a owl:Class ; rdfs:label "positive regulation of cell adhesion" ; rdfs:subClassOf obo:GO_0030155, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007155 ] ) ] . obo:GO_0045786 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." ; oboInOwl:hasExactSynonym "down regulation of progression through cell cycle", "down-regulation of progression through cell cycle", "downregulation of progression through cell cycle", "negative regulation of cell cycle progression", "negative regulation of progression through cell cycle" ; oboInOwl:hasNarrowSynonym "inhibition of progression through cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045786" ; a owl:Class ; rdfs:label "negative regulation of cell cycle" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0051726, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0045787 obo:IAO_0000115 "Any process that activates or increases the rate or extent of progression through the cell cycle." ; oboInOwl:hasExactSynonym "positive regulation of cell cycle progression", "positive regulation of progression through cell cycle", "up regulation of progression through cell cycle", "up-regulation of progression through cell cycle", "upregulation of progression through cell cycle" ; oboInOwl:hasNarrowSynonym "activation of progression through cell cycle", "stimulation of progression through cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045787" ; a owl:Class ; rdfs:label "positive regulation of cell cycle" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0051726, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0045806 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis." ; oboInOwl:hasExactSynonym "down regulation of endocytosis", "down-regulation of endocytosis", "downregulation of endocytosis" ; oboInOwl:hasNarrowSynonym "inhibition of endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045806" ; a owl:Class ; rdfs:label "negative regulation of endocytosis" ; rdfs:subClassOf obo:GO_0030100, obo:GO_0051051, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006897 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006897 ] ) ] . obo:GO_0045807 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of endocytosis." ; oboInOwl:hasExactSynonym "up regulation of endocytosis", "up-regulation of endocytosis", "upregulation of endocytosis" ; oboInOwl:hasNarrowSynonym "activation of endocytosis", "stimulation of endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045807" ; a owl:Class ; rdfs:label "positive regulation of endocytosis" ; rdfs:subClassOf obo:GO_0030100, obo:GO_0051050, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006897 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006897 ] ) ] . obo:GO_0045818 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." ; oboInOwl:hasExactSynonym "down regulation of glycogen catabolic process", "down-regulation of glycogen catabolic process", "downregulation of glycogen catabolic process", "negative regulation of glycogen breakdown", "negative regulation of glycogen catabolism", "negative regulation of glycogen degradation", "negative regulation of glycogenolysis" ; oboInOwl:hasNarrowSynonym "inhibition of glycogen catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045818" ; a owl:Class ; rdfs:label "negative regulation of glycogen catabolic process" ; rdfs:subClassOf obo:GO_0005981, obo:GO_0031330, obo:GO_0070874, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005980 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005980 ] ) ] . obo:GO_0045819 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen." ; oboInOwl:hasExactSynonym "positive regulation of glycogen breakdown", "positive regulation of glycogen catabolism", "positive regulation of glycogen degradation", "positive regulation of glycogenolysis", "up regulation of glycogen catabolic process", "up-regulation of glycogen catabolic process", "upregulation of glycogen catabolic process" ; oboInOwl:hasNarrowSynonym "activation of glycogen catabolic process", "stimulation of glycogen catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045819" ; a owl:Class ; rdfs:label "positive regulation of glycogen catabolic process" ; rdfs:subClassOf obo:GO_0005981, obo:GO_0031331, obo:GO_0070875, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005980 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005980 ] ) ] . obo:GO_0045822 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction." ; oboInOwl:hasExactSynonym "down regulation of heart contraction", "down-regulation of heart contraction", "downregulation of heart contraction" ; oboInOwl:hasNarrowSynonym "inhibition of heart contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cardiac contraction" ; oboInOwl:id "GO:0045822" ; a owl:Class ; rdfs:label "negative regulation of heart contraction" ; rdfs:subClassOf obo:GO_0008016, obo:GO_1903523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060047 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060047 ] ) ] . obo:GO_0045823 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of heart contraction." ; oboInOwl:hasExactSynonym "positive regulation of cardiac contraction", "up regulation of heart contraction", "up-regulation of heart contraction", "upregulation of heart contraction" ; oboInOwl:hasNarrowSynonym "activation of heart contraction", "stimulation of heart contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045823" ; a owl:Class ; rdfs:label "positive regulation of heart contraction" ; rdfs:subClassOf obo:GO_0008016, obo:GO_1903524, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060047 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060047 ] ) ] . obo:GO_0045824 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response." ; oboInOwl:hasExactSynonym "down regulation of innate immune response", "down-regulation of innate immune response", "downregulation of innate immune response" ; oboInOwl:hasNarrowSynonym "inhibition of innate immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045824" ; a owl:Class ; rdfs:label "negative regulation of innate immune response" ; rdfs:subClassOf obo:GO_0002832, obo:GO_0031348, obo:GO_0032102, obo:GO_0045088, obo:GO_0050777, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045087 ] ) ] . obo:GO_0045833 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." ; oboInOwl:hasExactSynonym "down regulation of lipid metabolic process", "down-regulation of lipid metabolic process", "downregulation of lipid metabolic process", "negative regulation of lipid metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of lipid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045833" ; a owl:Class ; rdfs:label "negative regulation of lipid metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0019216, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006629 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006629 ] ) ] . obo:GO_0045834 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." ; oboInOwl:hasExactSynonym "positive regulation of lipid metabolism", "up regulation of lipid metabolic process", "up-regulation of lipid metabolic process", "upregulation of lipid metabolic process" ; oboInOwl:hasNarrowSynonym "activation of lipid metabolic process", "stimulation of lipid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045834" ; a owl:Class ; rdfs:label "positive regulation of lipid metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0019216, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006629 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006629 ] ) ] . obo:GO_0045835 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." ; oboInOwl:hasExactSynonym "down regulation of meiosis", "down-regulation of meiosis", "downregulation of meiosis", "negative regulation of meiosis" ; oboInOwl:hasNarrowSynonym "inhibition of meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045835" ; a owl:Class ; rdfs:label "negative regulation of meiotic nuclear division" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0040020, obo:GO_0051447, obo:GO_0051784, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0140013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0045836 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of meiosis." ; oboInOwl:hasExactSynonym "positive regulation of meiosis", "up regulation of meiosis", "up-regulation of meiosis", "upregulation of meiosis" ; oboInOwl:hasNarrowSynonym "activation of meiosis", "stimulation of meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045836" ; a owl:Class ; rdfs:label "positive regulation of meiotic nuclear division" ; rdfs:subClassOf obo:GO_0040020, obo:GO_0051446, obo:GO_0051785, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0140013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0045839 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." ; oboInOwl:hasExactSynonym "down regulation of mitosis", "down-regulation of mitosis", "downregulation of mitosis", "negative regulation of mitosis" ; oboInOwl:hasNarrowSynonym "inhibition of mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045839" ; a owl:Class ; rdfs:label "negative regulation of mitotic nuclear division" ; rdfs:subClassOf obo:GO_0007088, obo:GO_0010948, obo:GO_0045930, obo:GO_0051784, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0045840 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitosis." ; oboInOwl:hasExactSynonym "positive regulation of mitosis", "up regulation of mitosis", "up-regulation of mitosis", "upregulation of mitosis" ; oboInOwl:hasNarrowSynonym "activation of mitosis", "mitogenic activity", "stimulation of mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045840" ; a owl:Class ; rdfs:label "positive regulation of mitotic nuclear division" ; rdfs:subClassOf obo:GO_0007088, obo:GO_0051785, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0045841 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ; oboInOwl:hasExactSynonym "down regulation of mitotic metaphase/anaphase transition", "down-regulation of mitotic metaphase/anaphase transition", "downregulation of mitotic metaphase/anaphase transition" ; oboInOwl:hasNarrowSynonym "inhibition of mitotic metaphase/anaphase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045841" ; a owl:Class ; rdfs:label "negative regulation of mitotic metaphase/anaphase transition" ; rdfs:subClassOf obo:GO_0030071, obo:GO_0045839, obo:GO_1901991, obo:GO_1902100, obo:GO_2000816, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007091 ] ) ] . obo:GO_0045842 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ; oboInOwl:hasExactSynonym "up regulation of mitotic metaphase/anaphase transition", "up-regulation of mitotic metaphase/anaphase transition", "upregulation of mitotic metaphase/anaphase transition" ; oboInOwl:hasNarrowSynonym "activation of mitotic metaphase/anaphase transition", "stimulation of mitotic metaphase/anaphase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045842" ; a owl:Class ; rdfs:label "positive regulation of mitotic metaphase/anaphase transition" ; rdfs:subClassOf obo:GO_0030071, obo:GO_0045840, obo:GO_1901970, obo:GO_1901992, obo:GO_1902101, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007091 ] ) ] . obo:GO_0045843 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development." ; oboInOwl:hasExactSynonym "down regulation of striated muscle development", "down-regulation of striated muscle development", "downregulation of striated muscle development" ; oboInOwl:hasNarrowSynonym "inhibition of striated muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045843" ; a owl:Class ; rdfs:label "negative regulation of striated muscle tissue development" ; rdfs:subClassOf obo:GO_0016202, obo:GO_0048635, obo:GO_1901862, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014706 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014706 ] ) ] . obo:GO_0045844 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of striated muscle development." ; oboInOwl:hasExactSynonym "up regulation of striated muscle development", "up-regulation of striated muscle development", "upregulation of striated muscle development" ; oboInOwl:hasNarrowSynonym "activation of striated muscle development", "stimulation of striated muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045844" ; a owl:Class ; rdfs:label "positive regulation of striated muscle tissue development" ; rdfs:subClassOf obo:GO_0016202, obo:GO_0048636, obo:GO_1901863, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014706 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014706 ] ) ] . obo:GO_0045892 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription." ; oboInOwl:hasAlternativeId "GO:0016481", "GO:0032582", "GO:0061021" ; oboInOwl:hasExactSynonym "down regulation of transcription, DNA-dependent", "down-regulation of transcription, DNA-dependent", "downregulation of transcription, DNA-dependent", "negative regulation of cellular transcription, DNA-dependent", "negative regulation of transcription, DNA-dependent", "negative regulation of transcription, DNA-templated" ; oboInOwl:hasNarrowSynonym "inhibition of transcription, DNA-dependent" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of gene-specific transcription", "down-regulation of gene-specific transcription", "downregulation of gene-specific transcription", "inhibition of gene-specific transcription", "negative regulation of gene-specific transcription", "transcription repressor activity" ; oboInOwl:id "GO:0045892" ; a owl:Class ; rdfs:label "negative regulation of DNA-templated transcription" ; rdfs:subClassOf obo:GO_0006355, obo:GO_1902679, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006351 ] ) ] . obo:GO_0045893 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription." ; oboInOwl:hasAlternativeId "GO:0043193", "GO:0045941", "GO:0061020" ; oboInOwl:hasExactSynonym "positive regulation of cellular transcription, DNA-dependent", "positive regulation of transcription, DNA-dependent", "positive regulation of transcription, DNA-templated", "up regulation of transcription, DNA-dependent", "up-regulation of transcription, DNA-dependent", "upregulation of transcription, DNA-dependent" ; oboInOwl:hasNarrowSynonym "activation of transcription, DNA-dependent", "stimulation of gene-specific transcription", "stimulation of transcription, DNA-dependent" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of gene-specific transcription", "positive regulation of gene-specific transcription", "transcription activator activity", "up regulation of gene-specific transcription", "up-regulation of gene-specific transcription", "upregulation of gene-specific transcription" ; oboInOwl:id "GO:0045893" ; a owl:Class ; rdfs:label "positive regulation of DNA-templated transcription" ; rdfs:subClassOf obo:GO_0006355, obo:GO_1902680, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006351 ] ) ] . obo:GO_0045900 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." ; oboInOwl:hasExactSynonym "down regulation of translational elongation", "down-regulation of translational elongation", "downregulation of translational elongation" ; oboInOwl:hasNarrowSynonym "inhibition of translational elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045900" ; a owl:Class ; rdfs:label "negative regulation of translational elongation" ; rdfs:subClassOf obo:GO_0006448, obo:GO_0017148, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006414 ] ) ] . obo:GO_0045901 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translational elongation." ; oboInOwl:hasExactSynonym "up regulation of translational elongation", "up-regulation of translational elongation", "upregulation of translational elongation" ; oboInOwl:hasNarrowSynonym "activation of translational elongation", "stimulation of translational elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045901" ; a owl:Class ; rdfs:label "positive regulation of translational elongation" ; rdfs:subClassOf obo:GO_0006448, obo:GO_0045727, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006414 ] ) ] . obo:GO_0045904 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination." ; oboInOwl:hasExactSynonym "down regulation of translational termination", "down-regulation of translational termination", "downregulation of translational termination" ; oboInOwl:hasNarrowSynonym "inhibition of translational termination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045904" ; a owl:Class ; rdfs:label "negative regulation of translational termination" ; rdfs:subClassOf obo:GO_0006449, obo:GO_0017148, obo:GO_0043242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006415 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006415 ] ) ] . obo:GO_0045905 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translational termination." ; oboInOwl:hasExactSynonym "up regulation of translational termination", "up-regulation of translational termination", "upregulation of translational termination" ; oboInOwl:hasNarrowSynonym "activation of translational termination", "stimulation of translational termination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045905" ; a owl:Class ; rdfs:label "positive regulation of translational termination" ; rdfs:subClassOf obo:GO_0006449, obo:GO_0043243, obo:GO_0045727, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006415 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006415 ] ) ] . obo:GO_0045910 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination." ; oboInOwl:hasExactSynonym "down regulation of DNA recombination", "down-regulation of DNA recombination", "downregulation of DNA recombination" ; oboInOwl:hasNarrowSynonym "inhibition of DNA recombination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045910" ; a owl:Class ; rdfs:label "negative regulation of DNA recombination" ; rdfs:subClassOf obo:GO_0000018, obo:GO_0051053, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006310 ] ) ] . obo:GO_0045911 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of DNA recombination." ; oboInOwl:hasExactSynonym "up regulation of DNA recombination", "up-regulation of DNA recombination", "upregulation of DNA recombination" ; oboInOwl:hasNarrowSynonym "activation of DNA recombination", "stimulation of DNA recombination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045911" ; a owl:Class ; rdfs:label "positive regulation of DNA recombination" ; rdfs:subClassOf obo:GO_0000018, obo:GO_0051054, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006310 ] ) ] . obo:GO_0045912 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." ; oboInOwl:hasExactSynonym "down regulation of carbohydrate metabolic process", "down-regulation of carbohydrate metabolic process", "downregulation of carbohydrate metabolic process", "negative regulation of carbohydrate metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of carbohydrate metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045912" ; a owl:Class ; rdfs:label "negative regulation of carbohydrate metabolic process" ; rdfs:subClassOf obo:GO_0006109, obo:GO_0009892, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005975 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005975 ] ) ] . obo:GO_0045913 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate." ; oboInOwl:hasExactSynonym "positive regulation of carbohydrate metabolism", "up regulation of carbohydrate metabolic process", "up-regulation of carbohydrate metabolic process", "upregulation of carbohydrate metabolic process" ; oboInOwl:hasNarrowSynonym "activation of carbohydrate metabolic process", "stimulation of carbohydrate metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045913" ; a owl:Class ; rdfs:label "positive regulation of carbohydrate metabolic process" ; rdfs:subClassOf obo:GO_0006109, obo:GO_0009893, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005975 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005975 ] ) ] . obo:GO_0045914 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." ; oboInOwl:hasExactSynonym "down regulation of catecholamine metabolic process", "down-regulation of catecholamine metabolic process", "downregulation of catecholamine metabolic process", "negative regulation of catecholamine metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of catecholamine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045914" ; a owl:Class ; rdfs:label "negative regulation of catecholamine metabolic process" ; rdfs:subClassOf obo:GO_0031324, obo:GO_0033239, obo:GO_0042069, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006584 ] ) ] . obo:GO_0045915 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." ; oboInOwl:hasExactSynonym "positive regulation of catecholamine metabolism", "up regulation of catecholamine metabolic process", "up-regulation of catecholamine metabolic process", "upregulation of catecholamine metabolic process" ; oboInOwl:hasNarrowSynonym "activation of catecholamine metabolic process", "stimulation of catecholamine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045915" ; a owl:Class ; rdfs:label "positive regulation of catecholamine metabolic process" ; rdfs:subClassOf obo:GO_0031325, obo:GO_0033240, obo:GO_0042069, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006584 ] ) ] . obo:GO_0045920 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." ; oboInOwl:hasExactSynonym "down regulation of exocytosis", "down-regulation of exocytosis", "downregulation of exocytosis" ; oboInOwl:hasNarrowSynonym "inhibition of exocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045920" ; a owl:Class ; rdfs:label "negative regulation of exocytosis" ; rdfs:subClassOf obo:GO_0017157, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006887 ] ) ] . obo:GO_0045921 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of exocytosis." ; oboInOwl:hasExactSynonym "up regulation of exocytosis", "up-regulation of exocytosis", "upregulation of exocytosis" ; oboInOwl:hasNarrowSynonym "activation of exocytosis", "stimulation of exocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045921" ; a owl:Class ; rdfs:label "positive regulation of exocytosis" ; rdfs:subClassOf obo:GO_0017157, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006887 ] ) ] . obo:GO_0045926 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." ; oboInOwl:hasExactSynonym "down regulation of growth", "down-regulation of growth", "downregulation of growth" ; oboInOwl:hasNarrowSynonym "inhibition of growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045926" ; a owl:Class ; rdfs:label "negative regulation of growth" ; rdfs:subClassOf obo:GO_0040008, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040007 ] ) ] . obo:GO_0045927 obo:IAO_0000115 "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." ; oboInOwl:hasExactSynonym "up regulation of growth", "up-regulation of growth", "upregulation of growth" ; oboInOwl:hasNarrowSynonym "activation of growth", "stimulation of growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045927" ; a owl:Class ; rdfs:label "positive regulation of growth" ; rdfs:subClassOf obo:GO_0040008, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040007 ] ) ] . obo:GO_0045930 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." ; oboInOwl:hasExactSynonym "down regulation of progression through mitotic cell cycle", "down-regulation of progression through mitotic cell cycle", "downregulation of progression through mitotic cell cycle", "negative regulation of mitotic cell cycle progression", "negative regulation of progression through mitotic cell cycle" ; oboInOwl:hasNarrowSynonym "inhibition of progression through mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045930" ; a owl:Class ; rdfs:label "negative regulation of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0007346, obo:GO_0045786, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0045931 obo:IAO_0000115 "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." ; oboInOwl:hasExactSynonym "positive regulation of mitotic cell cycle progression", "positive regulation of progression through mitotic cell cycle", "up regulation of progression through mitotic cell cycle", "up-regulation of progression through mitotic cell cycle", "upregulation of progression through mitotic cell cycle" ; oboInOwl:hasNarrowSynonym "activation of progression through mitotic cell cycle", "stimulation of progression through mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045931" ; a owl:Class ; rdfs:label "positive regulation of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0007346, obo:GO_0045787, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0045932 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." ; oboInOwl:hasExactSynonym "down regulation of muscle contraction", "down-regulation of muscle contraction", "downregulation of muscle contraction" ; oboInOwl:hasNarrowSynonym "inhibition of muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045932" ; a owl:Class ; rdfs:label "negative regulation of muscle contraction" ; rdfs:subClassOf obo:GO_0006937, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006936 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006936 ] ) ] . obo:GO_0045933 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of muscle contraction." ; oboInOwl:hasExactSynonym "up regulation of muscle contraction", "up-regulation of muscle contraction", "upregulation of muscle contraction" ; oboInOwl:hasNarrowSynonym "activation of muscle contraction", "stimulation of muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045933" ; a owl:Class ; rdfs:label "positive regulation of muscle contraction" ; rdfs:subClassOf obo:GO_0006937, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006936 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006936 ] ) ] . obo:GO_0045934 obo:IAO_0000115 "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:id "GO:0045934" ; a owl:Class ; rdfs:label "negative regulation of nucleobase-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0019219, obo:GO_0031324, obo:GO_0051172, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006139 ] ) ] . obo:GO_0045935 obo:IAO_0000115 "Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism", "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:hasNarrowSynonym "activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:id "GO:0045935" ; a owl:Class ; rdfs:label "positive regulation of nucleobase-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0019219, obo:GO_0031325, obo:GO_0051173, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006139 ] ) ] . obo:GO_0045936 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ; oboInOwl:hasExactSynonym "down regulation of phosphate metabolic process", "down-regulation of phosphate metabolic process", "downregulation of phosphate metabolic process", "negative regulation of phosphate metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of phosphate metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045936" ; a owl:Class ; rdfs:label "negative regulation of phosphate metabolic process" ; rdfs:subClassOf obo:GO_0010563, obo:GO_0019220, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006796 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006796 ] ) ] . obo:GO_0045937 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ; oboInOwl:hasExactSynonym "positive regulation of phosphate metabolism", "up regulation of phosphate metabolic process", "up-regulation of phosphate metabolic process", "upregulation of phosphate metabolic process" ; oboInOwl:hasNarrowSynonym "activation of phosphate metabolic process", "stimulation of phosphate metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045937" ; a owl:Class ; rdfs:label "positive regulation of phosphate metabolic process" ; rdfs:subClassOf obo:GO_0010562, obo:GO_0019220, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006796 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006796 ] ) ] . obo:GO_0045939 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids." ; oboInOwl:hasExactSynonym "down regulation of steroid metabolic process", "down-regulation of steroid metabolic process", "downregulation of steroid metabolic process", "negative regulation of steroid metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of steroid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045939" ; a owl:Class ; rdfs:label "negative regulation of steroid metabolic process" ; rdfs:subClassOf obo:GO_0019218, obo:GO_0045833, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008202 ] ) ] . obo:GO_0045940 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids." ; oboInOwl:hasExactSynonym "positive regulation of steroid metabolism", "up regulation of steroid metabolic process", "up-regulation of steroid metabolic process", "upregulation of steroid metabolic process" ; oboInOwl:hasNarrowSynonym "activation of steroid metabolic process", "stimulation of steroid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045940" ; a owl:Class ; rdfs:label "positive regulation of steroid metabolic process" ; rdfs:subClassOf obo:GO_0019218, obo:GO_0045834, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008202 ] ) ] . obo:GO_0045944 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter." ; oboInOwl:hasAlternativeId "GO:0010552", "GO:0045817" ; oboInOwl:hasExactSynonym "activation of transcription from RNA polymerase II promoter", "positive regulation of transcription from Pol II promoter", "positive regulation of transcription from RNA polymerase II promoter", "stimulation of transcription from RNA polymerase II promoter", "up regulation of transcription from RNA polymerase II promoter", "up-regulation of transcription from RNA polymerase II promoter", "upregulation of transcription from RNA polymerase II promoter" ; oboInOwl:hasNarrowSynonym "stimulation of global transcription from RNA polymerase II promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of global transcription from RNA polymerase II promoter", "positive regulation of gene-specific transcription from RNA polymerase II promoter", "positive regulation of global transcription from Pol II promoter", "positive regulation of transcription from RNA polymerase II promoter, global", "up regulation of global transcription from RNA polymerase II promoter", "up-regulation of global transcription from RNA polymerase II promoter", "upregulation of global transcription from RNA polymerase II promoter" ; oboInOwl:id "GO:0045944" ; a owl:Class ; rdfs:label "positive regulation of transcription by RNA polymerase II" ; rdfs:subClassOf obo:GO_0006357, obo:GO_0045893, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006366 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006366 ] ) ] . obo:GO_0045947 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation." ; oboInOwl:hasExactSynonym "down regulation of translational initiation", "down-regulation of translational initiation", "downregulation of translational initiation" ; oboInOwl:hasNarrowSynonym "inhibition of translational initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045947" ; a owl:Class ; rdfs:label "negative regulation of translational initiation" ; rdfs:subClassOf obo:GO_0006446, obo:GO_0017148, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006413 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006413 ] ) ] . obo:GO_0045948 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translational initiation." ; oboInOwl:hasExactSynonym "up regulation of translational initiation", "up-regulation of translational initiation", "upregulation of translational initiation" ; oboInOwl:hasNarrowSynonym "activation of translational initiation", "stimulation of translational initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045948" ; a owl:Class ; rdfs:label "positive regulation of translational initiation" ; rdfs:subClassOf obo:GO_0006446, obo:GO_0045727, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006413 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006413 ] ) ] . obo:GO_0045963 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ; oboInOwl:hasExactSynonym "down regulation of dopamine metabolic process", "down-regulation of dopamine metabolic process", "downregulation of dopamine metabolic process", "negative regulation of dopamine metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of dopamine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045963" ; a owl:Class ; rdfs:label "negative regulation of dopamine metabolic process" ; rdfs:subClassOf obo:GO_0042053, obo:GO_0045914, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042417 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042417 ] ) ] . obo:GO_0045964 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ; oboInOwl:hasExactSynonym "positive regulation of dopamine metabolism", "up regulation of dopamine metabolic process", "up-regulation of dopamine metabolic process", "upregulation of dopamine metabolic process" ; oboInOwl:hasNarrowSynonym "activation of dopamine metabolic process", "stimulation of dopamine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045964" ; a owl:Class ; rdfs:label "positive regulation of dopamine metabolic process" ; rdfs:subClassOf obo:GO_0042053, obo:GO_0045915, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042417 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042417 ] ) ] . obo:GO_0045986 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction." ; oboInOwl:hasExactSynonym "down regulation of smooth muscle contraction", "down-regulation of smooth muscle contraction", "downregulation of smooth muscle contraction" ; oboInOwl:hasNarrowSynonym "inhibition of smooth muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "smooth muscle relaxation" ; oboInOwl:id "GO:0045986" ; a owl:Class ; rdfs:label "negative regulation of smooth muscle contraction" ; rdfs:subClassOf obo:GO_0006940, obo:GO_0045932, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006939 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006939 ] ) ] . obo:GO_0045987 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction." ; oboInOwl:hasExactSynonym "up regulation of smooth muscle contraction", "up-regulation of smooth muscle contraction", "upregulation of smooth muscle contraction" ; oboInOwl:hasNarrowSynonym "activation of smooth muscle contraction", "stimulation of smooth muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045987" ; a owl:Class ; rdfs:label "positive regulation of smooth muscle contraction" ; rdfs:subClassOf obo:GO_0006940, obo:GO_0045933, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006939 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006939 ] ) ] . obo:GO_0045988 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction." ; oboInOwl:hasExactSynonym "down regulation of striated muscle contraction", "down-regulation of striated muscle contraction", "downregulation of striated muscle contraction" ; oboInOwl:hasNarrowSynonym "inhibition of striated muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045988" ; a owl:Class ; rdfs:label "negative regulation of striated muscle contraction" ; rdfs:subClassOf obo:GO_0006942, obo:GO_0045932, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006941 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006941 ] ) ] . obo:GO_0045989 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of striated muscle contraction." ; oboInOwl:hasExactSynonym "up regulation of striated muscle contraction", "up-regulation of striated muscle contraction", "upregulation of striated muscle contraction" ; oboInOwl:hasNarrowSynonym "activation of striated muscle contraction", "stimulation of striated muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045989" ; a owl:Class ; rdfs:label "positive regulation of striated muscle contraction" ; rdfs:subClassOf obo:GO_0006942, obo:GO_0045933, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006941 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006941 ] ) ] . obo:GO_0045992 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." ; oboInOwl:hasExactSynonym "down regulation of embryonic development", "down-regulation of embryonic development", "downregulation of embryonic development" ; oboInOwl:hasNarrowSynonym "inhibition of embryonic development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045992" ; a owl:Class ; rdfs:label "negative regulation of embryonic development" ; rdfs:subClassOf obo:GO_0045995, obo:GO_0051093, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009790 ] ) ] . obo:GO_0045995 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of embryonic development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045995" ; a owl:Class ; rdfs:label "regulation of embryonic development" ; rdfs:subClassOf obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009790 ] ) ] . obo:GO_0046013 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of resting T cell proliferation." ; oboInOwl:hasExactSynonym "regulation of T lymphocyte homeostatic proliferation", "regulation of T-cell homeostatic proliferation", "regulation of T-lymphocyte homeostatic proliferation", "regulation of resting T cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046013" ; a owl:Class ; rdfs:label "regulation of T cell homeostatic proliferation" ; rdfs:subClassOf obo:GO_0042129, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001777 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001777 ] ) ] . obo:GO_0046014 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation." ; oboInOwl:hasExactSynonym "down regulation of T cell homeostatic proliferation", "down-regulation of T cell homeostatic proliferation", "downregulation of T cell homeostatic proliferation", "negative regulation of T lymphocyte homeostatic proliferation", "negative regulation of T-cell homeostatic proliferation", "negative regulation of T-lymphocyte homeostatic proliferation", "negative regulation of resting T cell proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of T cell homeostatic proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046014" ; a owl:Class ; rdfs:label "negative regulation of T cell homeostatic proliferation" ; rdfs:subClassOf obo:GO_0042130, obo:GO_0046013, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001777 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001777 ] ) ] . obo:GO_0046112 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." ; oboInOwl:hasExactSynonym "nucleobase anabolism", "nucleobase biosynthesis", "nucleobase formation", "nucleobase synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046112" ; a owl:Class ; rdfs:label "nucleobase biosynthetic process" ; rdfs:subClassOf obo:GO_0009112, obo:GO_0018130, obo:GO_1901362, obo:GO_1901566, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18282 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_18282 ] ) ] . obo:GO_0046113 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid." ; oboInOwl:hasExactSynonym "nucleobase breakdown", "nucleobase catabolism", "nucleobase degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046113" ; a owl:Class ; rdfs:label "nucleobase catabolic process" ; rdfs:subClassOf obo:GO_0009112, obo:GO_0046700, obo:GO_1901361, obo:GO_1901565, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18282 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_18282 ] ) ] . obo:GO_0046189 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ; oboInOwl:hasExactSynonym "phenol-containing compound anabolism", "phenol-containing compound biosynthesis", "phenol-containing compound formation", "phenol-containing compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046189" ; a owl:Class ; rdfs:label "phenol-containing compound biosynthetic process" ; rdfs:subClassOf obo:GO_0018958, obo:GO_0019438, obo:GO_1901362, obo:GO_1901617, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33853 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_33853 ] ) ] . obo:GO_0046219 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group." ; oboInOwl:hasExactSynonym "indolalkylamine anabolism", "indolalkylamine biosynthesis", "indolalkylamine formation", "indolalkylamine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046219" ; a owl:Class ; rdfs:label "indolalkylamine biosynthetic process" ; rdfs:subClassOf obo:GO_0006586, obo:GO_0042401, obo:GO_0042435, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_38631 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_38631 ] ) ] . obo:GO_0046333 obo:IAO_0000115 "The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species." ; oboInOwl:hasExactSynonym "octopamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046333" ; a owl:Class ; rdfs:label "octopamine metabolic process" ; rdfs:subClassOf obo:GO_0018958, obo:GO_0042133, obo:GO_0042439 . obo:GO_0046364 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." ; oboInOwl:hasExactSynonym "monosaccharide anabolism", "monosaccharide biosynthesis", "monosaccharide formation", "monosaccharide synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046364" ; a owl:Class ; rdfs:label "monosaccharide biosynthetic process" ; rdfs:subClassOf obo:GO_0005996, obo:GO_0016051, obo:GO_0044283, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_35381 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_35381 ] ) ] . obo:GO_0046365 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms." ; oboInOwl:hasExactSynonym "monosaccharide breakdown", "monosaccharide catabolism", "monosaccharide degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046365" ; a owl:Class ; rdfs:label "monosaccharide catabolic process" ; rdfs:subClassOf obo:GO_0005996, obo:GO_0016052, obo:GO_0044282, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35381 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35381 ] ) ] . obo:GO_0046394 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." ; oboInOwl:hasExactSynonym "carboxylic acid anabolism", "carboxylic acid biosynthesis", "carboxylic acid formation", "carboxylic acid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046394" ; a owl:Class ; rdfs:label "carboxylic acid biosynthetic process" ; rdfs:subClassOf obo:GO_0016053, obo:GO_0019752, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_29067 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_29067 ] ) ] . obo:GO_0046395 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups." ; oboInOwl:hasExactSynonym "carboxylic acid breakdown", "carboxylic acid catabolism", "carboxylic acid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046395" ; a owl:Class ; rdfs:label "carboxylic acid catabolic process" ; rdfs:subClassOf obo:GO_0016054, obo:GO_0019752, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29067 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29067 ] ) ] . obo:GO_0046483 obo:IAO_0000115 "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." ; oboInOwl:hasExactSynonym "heterocycle metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046483" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "heterocycle metabolic process" ; rdfs:subClassOf obo:GO_0044237, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_5686 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_5686 ] ) ] . obo:GO_0046530 obo:IAO_0000115 "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0007467" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046530" ; a owl:Class ; rdfs:label "photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0030182, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000210 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000210 ] ) ] . obo:GO_0046532 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0045673" ; oboInOwl:hasExactSynonym "regulation of photoreceptor differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046532" ; a owl:Class ; rdfs:label "regulation of photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0045664, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046530 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046530 ] ) ] . obo:GO_0046533 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0045674" ; oboInOwl:hasExactSynonym "down regulation of photoreceptor cell differentiation", "down regulation of photoreceptor differentiation", "down-regulation of photoreceptor cell differentiation", "down-regulation of photoreceptor differentiation", "downregulation of photoreceptor cell differentiation", "downregulation of photoreceptor differentiation", "negative regulation of photoreceptor differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of photoreceptor cell differentiation", "inhibition of photoreceptor differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046533" ; a owl:Class ; rdfs:label "negative regulation of photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0045665, obo:GO_0046532, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046530 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046530 ] ) ] . obo:GO_0046534 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0045675" ; oboInOwl:hasExactSynonym "positive regulation of photoreceptor differentiation", "up regulation of photoreceptor cell differentiation", "up regulation of photoreceptor differentiation", "up-regulation of photoreceptor cell differentiation", "up-regulation of photoreceptor differentiation", "upregulation of photoreceptor cell differentiation", "upregulation of photoreceptor differentiation" ; oboInOwl:hasNarrowSynonym "activation of photoreceptor cell differentiation", "activation of photoreceptor differentiation", "stimulation of photoreceptor cell differentiation", "stimulation of photoreceptor differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046534" ; a owl:Class ; rdfs:label "positive regulation of photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0045666, obo:GO_0046532, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046530 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046530 ] ) ] . obo:GO_0046545 obo:IAO_0000115 "The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046545" ; a owl:Class ; rdfs:label "development of primary female sexual characteristics" ; rdfs:subClassOf obo:GO_0045137, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046660 ] . obo:GO_0046546 obo:IAO_0000115 "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046546" ; a owl:Class ; rdfs:label "development of primary male sexual characteristics" ; rdfs:subClassOf obo:GO_0045137, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046661 ] . obo:GO_0046548 obo:IAO_0000115 "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046548" ; a owl:Class ; rdfs:label "retinal rod cell development" ; rdfs:subClassOf obo:GO_0042462, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060221 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000604 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000604 ] ) ] . obo:GO_0046549 obo:IAO_0000115 "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046549" ; a owl:Class ; rdfs:label "retinal cone cell development" ; rdfs:subClassOf obo:GO_0042462, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042670 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000573 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000573 ] ) ] . obo:GO_0046620 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of growth of an organ of an organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046620" ; a owl:Class ; rdfs:label "regulation of organ growth" ; rdfs:subClassOf obo:GO_0048638, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035265 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035265 ] ) ] . obo:GO_0046621 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046621" ; a owl:Class ; rdfs:label "negative regulation of organ growth" ; rdfs:subClassOf obo:GO_0046620, obo:GO_0048640, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035265 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035265 ] ) ] . obo:GO_0046622 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046622" ; a owl:Class ; rdfs:label "positive regulation of organ growth" ; rdfs:subClassOf obo:GO_0046620, obo:GO_0048639, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035265 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035265 ] ) ] . obo:GO_0046649 obo:IAO_0000115 "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046649" ; a owl:Class ; rdfs:label "lymphocyte activation" ; rdfs:subClassOf obo:GO_0045321, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000542 ] ) ] . obo:GO_0046651 obo:IAO_0000115 "The expansion of a lymphocyte population by cell division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046651" ; a owl:Class ; rdfs:label "lymphocyte proliferation" ; rdfs:subClassOf obo:GO_0032943, obo:GO_0046649, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000542 ] ) ] . obo:GO_0046660 obo:IAO_0000115 "The establishment of the sex of a female organism by physical differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046660" ; a owl:Class ; rdfs:label "female sex differentiation" ; rdfs:subClassOf obo:GO_0007548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0046661 obo:IAO_0000115 "The establishment of the sex of a male organism by physical differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046661" ; a owl:Class ; rdfs:label "male sex differentiation" ; rdfs:subClassOf obo:GO_0007548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0046662 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium." ; oboInOwl:hasAlternativeId "GO:0048042" ; oboInOwl:hasExactSynonym "regulation of oviposition" ; oboInOwl:hasNarrowSynonym "regulation of post-mating oviposition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046662" ; a owl:Class ; rdfs:label "regulation of egg-laying behavior" ; rdfs:subClassOf obo:GO_0050795, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0018991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0018991 ] ) ] . obo:GO_0046666 obo:IAO_0000115 "Programmed cell death that occurs in the developing retina." ; oboInOwl:hasExactSynonym "programmed cell death, retina cells", "programmed cell death, retinal cells", "retina cell programmed cell death", "retina programmed cell death", "retinal programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046666" ; a owl:Class ; rdfs:label "retinal cell programmed cell death" ; rdfs:subClassOf obo:GO_0010623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048592 ] . obo:GO_0046667 obo:IAO_0000115 "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046667" ; a owl:Class ; rdfs:label "compound eye retinal cell programmed cell death" ; rdfs:subClassOf obo:GO_0046666, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001745 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000018 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046666 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000018 ] ) ] . obo:GO_0046668 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina." ; oboInOwl:hasExactSynonym "regulation of retinal programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046668" ; a owl:Class ; rdfs:label "regulation of retinal cell programmed cell death" ; rdfs:subClassOf obo:GO_0043067, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046666 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046666 ] ) ] . obo:GO_0046669 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." ; oboInOwl:hasBroadSynonym "regulation of retinal cell programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046669" ; a owl:Class ; rdfs:label "regulation of compound eye retinal cell programmed cell death" ; rdfs:subClassOf obo:GO_0046668, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046667 ] ) ] . obo:GO_0046670 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina." ; oboInOwl:hasExactSynonym "positive regulation of retinal programmed cell death", "up regulation of retinal programmed cell death", "up-regulation of retinal programmed cell death", "upregulation of retinal programmed cell death" ; oboInOwl:hasNarrowSynonym "activation of retinal programmed cell death", "stimulation of retinal programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046670" ; a owl:Class ; rdfs:label "positive regulation of retinal cell programmed cell death" ; rdfs:subClassOf obo:GO_0043068, obo:GO_0046668, obo:GO_0051094, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046666 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046666 ] ) ] . obo:GO_0046671 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina." ; oboInOwl:hasExactSynonym "down regulation of retinal programmed cell death", "down-regulation of retinal programmed cell death", "downregulation of retinal programmed cell death", "negative regulation of retinal programmed cell death" ; oboInOwl:hasNarrowSynonym "inhibition of retinal programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046671" ; a owl:Class ; rdfs:label "negative regulation of retinal cell programmed cell death" ; rdfs:subClassOf obo:GO_0043069, obo:GO_0046668, obo:GO_0051093, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046666 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046666 ] ) ] . obo:GO_0046672 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." ; oboInOwl:hasBroadSynonym "activation of retinal cell programmed cell death", "positive regulation of retinal cell programmed cell death", "stimulation of retinal cell programmed cell death", "up regulation of retinal cell programmed cell death", "up-regulation of retinal cell programmed cell death", "upregulation of retinal cell programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046672" ; a owl:Class ; rdfs:label "positive regulation of compound eye retinal cell programmed cell death" ; rdfs:subClassOf obo:GO_0046669, obo:GO_0046670, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046667 ] ) ] . obo:GO_0046673 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina." ; oboInOwl:hasBroadSynonym "down regulation of retinal cell programmed cell death", "down-regulation of retinal cell programmed cell death", "downregulation of retinal cell programmed cell death", "inhibition of retinal cell programmed cell death", "negative regulation of retina cell programmed cell death", "negative regulation of retinal cell programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046673" ; a owl:Class ; rdfs:label "negative regulation of compound eye retinal cell programmed cell death" ; rdfs:subClassOf obo:GO_0046669, obo:GO_0046671, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046667 ] ) ] . obo:GO_0046676 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin." ; oboInOwl:hasExactSynonym "down regulation of insulin secretion", "down-regulation of insulin secretion", "downregulation of insulin secretion" ; oboInOwl:hasNarrowSynonym "inhibition of insulin secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046676" ; a owl:Class ; rdfs:label "negative regulation of insulin secretion" ; rdfs:subClassOf obo:GO_0050709, obo:GO_0050796, obo:GO_0090278, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030073 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030073 ] ) ] . obo:GO_0046681 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "carbamate resistance", "carbamate susceptibility/resistance" ; oboInOwl:id "GO:0046681" ; a owl:Class ; rdfs:label "response to carbamate" ; rdfs:subClassOf obo:GO_0010243, obo:GO_0017085, obo:GO_1901700, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_13941 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_13941 ] ) ] . obo:GO_0046700 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." ; oboInOwl:hasExactSynonym "heterocycle breakdown", "heterocycle catabolism", "heterocycle degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046700" ; a owl:Class ; rdfs:label "heterocycle catabolic process" ; rdfs:subClassOf obo:GO_0044248, obo:GO_0046483, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_5686 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_5686 ] ) ] . obo:GO_0046716 obo:IAO_0000115 "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24218"^^xsd:anyURI ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasNarrowSynonym "muscle fiber maintenance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "muscle homeostasis" ; oboInOwl:id "GO:0046716" ; a owl:Class ; rdfs:label "muscle cell cellular homeostasis" ; rdfs:subClassOf obo:GO_0019725, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000187 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4751 ] ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019725 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:GO_0046717 obo:IAO_0000115 "The controlled release of acid by a cell or a tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046717" ; a owl:Class ; rdfs:label "acid secretion" ; rdfs:subClassOf obo:GO_0046903 . obo:GO_0046785 obo:IAO_0000115 "The addition of tubulin heterodimers to one or both ends of a microtubule." ; oboInOwl:hasExactSynonym "microtubule assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microtubule formation" ; oboInOwl:id "GO:0046785" ; a owl:Class ; rdfs:label "microtubule polymerization" ; rdfs:subClassOf obo:GO_0031109, obo:GO_0051258, obo:GO_0097435, [ a owl:Restriction ; owl:onProperty obo:RO_0002224 ; owl:someValuesFrom obo:GO_0007020 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005874 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0046822 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046822" ; a owl:Class ; rdfs:label "regulation of nucleocytoplasmic transport" ; rdfs:subClassOf obo:GO_0032386, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006913 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006913 ] ) ] . obo:GO_0046823 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus." ; oboInOwl:hasExactSynonym "down regulation of nucleocytoplasmic transport", "down-regulation of nucleocytoplasmic transport", "downregulation of nucleocytoplasmic transport" ; oboInOwl:hasNarrowSynonym "inhibition of nucleocytoplasmic transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046823" ; a owl:Class ; rdfs:label "negative regulation of nucleocytoplasmic transport" ; rdfs:subClassOf obo:GO_0032387, obo:GO_0046822, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006913 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006913 ] ) ] . obo:GO_0046824 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." ; oboInOwl:hasExactSynonym "up regulation of nucleocytoplasmic transport", "up-regulation of nucleocytoplasmic transport", "upregulation of nucleocytoplasmic transport" ; oboInOwl:hasNarrowSynonym "activation of nucleocytoplasmic transport", "stimulation of nucleocytoplasmic transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046824" ; a owl:Class ; rdfs:label "positive regulation of nucleocytoplasmic transport" ; rdfs:subClassOf obo:GO_0032388, obo:GO_0046822, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006913 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006913 ] ) ] . obo:GO_0046825 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm." ; oboInOwl:hasExactSynonym "regulation of protein export from cell nucleus", "regulation of protein export out of nucleus", "regulation of protein transport from nucleus to cytoplasm", "regulation of protein-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046825" ; a owl:Class ; rdfs:label "regulation of protein export from nucleus" ; rdfs:subClassOf obo:GO_0033157, obo:GO_0046822, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006611 ] ) ] . obo:GO_0046826 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm." ; oboInOwl:hasExactSynonym "down regulation of protein export from nucleus", "down-regulation of protein export from nucleus", "downregulation of protein export from nucleus", "negative regulation of protein export from cell nucleus", "negative regulation of protein export out of nucleus", "negative regulation of protein transport from nucleus to cytoplasm", "negative regulation of protein-nucleus export" ; oboInOwl:hasNarrowSynonym "inhibition of protein export from nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046826" ; a owl:Class ; rdfs:label "negative regulation of protein export from nucleus" ; rdfs:subClassOf obo:GO_0046823, obo:GO_0046825, obo:GO_0051457, obo:GO_0090317, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006611 ] ) ] . obo:GO_0046827 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm." ; oboInOwl:hasExactSynonym "positive regulation of protein export from cell nucleus", "positive regulation of protein export out of nucleus", "positive regulation of protein transport from nucleus to cytoplasm", "positive regulation of protein-nucleus export", "up regulation of protein export from nucleus", "up-regulation of protein export from nucleus", "upregulation of protein export from nucleus" ; oboInOwl:hasNarrowSynonym "activation of protein export from nucleus", "stimulation of protein export from nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046827" ; a owl:Class ; rdfs:label "positive regulation of protein export from nucleus" ; rdfs:subClassOf obo:GO_0046824, obo:GO_0046825, obo:GO_0090316, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006611 ] ) ] . obo:GO_0046831 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm." ; oboInOwl:hasExactSynonym "regulation of RNA export from cell nucleus", "regulation of RNA export out of nucleus", "regulation of RNA transport from nucleus to cytoplasm", "regulation of RNA-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046831" ; a owl:Class ; rdfs:label "regulation of RNA export from nucleus" ; rdfs:subClassOf obo:GO_0032239, obo:GO_0046822, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006405 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006405 ] ) ] . obo:GO_0046832 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm." ; oboInOwl:hasExactSynonym "down regulation of RNA export from nucleus", "down-regulation of RNA export from nucleus", "downregulation of RNA export from nucleus", "negative regulation of RNA export from cell nucleus", "negative regulation of RNA export out of nucleus", "negative regulation of RNA transport from nucleus to cytoplasm", "negative regulation of RNA-nucleus export" ; oboInOwl:hasNarrowSynonym "inhibition of RNA export from nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046832" ; a owl:Class ; rdfs:label "negative regulation of RNA export from nucleus" ; rdfs:subClassOf obo:GO_0032240, obo:GO_0046823, obo:GO_0046831, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006405 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006405 ] ) ] . obo:GO_0046833 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm." ; oboInOwl:hasExactSynonym "positive regulation of RNA export from cell nucleus", "positive regulation of RNA export out of nucleus", "positive regulation of RNA transport from nucleus to cytoplasm", "positive regulation of RNA-nucleus export", "up regulation of RNA export from nucleus", "up-regulation of RNA export from nucleus", "upregulation of RNA export from nucleus" ; oboInOwl:hasNarrowSynonym "activation of RNA export from nucleus", "stimulation of RNA export from nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046833" ; a owl:Class ; rdfs:label "positive regulation of RNA export from nucleus" ; rdfs:subClassOf obo:GO_0032241, obo:GO_0046824, obo:GO_0046831, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006405 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006405 ] ) ] . obo:GO_0046873 obo:IAO_0000115 "Enables the transfer of metal ions from one side of a membrane to the other." ; oboInOwl:hasNarrowSynonym "heavy metal ion porter activity", "heavy metal ion transporter activity", "heavy metal ion:hydrogen symporter activity", "heavy metal-exporting ATPase activity", "high affinity metal ion uptake transporter activity", "low affinity metal ion uptake transporter activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0046873" ; a owl:Class ; rdfs:label "metal ion transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0008324, obo:GO_0022890, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25213 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_25213 ] ) ] . obo:GO_0046879 obo:IAO_0000115 "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046879" ; a owl:Class ; rdfs:label "hormone secretion" ; rdfs:subClassOf obo:GO_0009914, obo:GO_0023061 . obo:GO_0046883 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046883" ; a owl:Class ; rdfs:label "regulation of hormone secretion" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0010817, obo:GO_0023051, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046879 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046879 ] ) ] . obo:GO_0046887 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell." ; oboInOwl:hasExactSynonym "up regulation of hormone secretion", "up-regulation of hormone secretion", "upregulation of hormone secretion" ; oboInOwl:hasNarrowSynonym "activation of hormone secretion", "stimulation of hormone secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046887" ; a owl:Class ; rdfs:label "positive regulation of hormone secretion" ; rdfs:subClassOf obo:GO_0010647, obo:GO_0023056, obo:GO_0046883, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046879 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046879 ] ) ] . obo:GO_0046888 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell." ; oboInOwl:hasExactSynonym "down regulation of hormone secretion", "down-regulation of hormone secretion", "downregulation of hormone secretion" ; oboInOwl:hasNarrowSynonym "inhibition of hormone secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046888" ; a owl:Class ; rdfs:label "negative regulation of hormone secretion" ; rdfs:subClassOf obo:GO_0010648, obo:GO_0023057, obo:GO_0046883, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046879 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046879 ] ) ] . obo:GO_0046889 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ; oboInOwl:hasExactSynonym "positive regulation of lipid anabolism", "positive regulation of lipid biosynthesis", "positive regulation of lipid formation", "positive regulation of lipid synthesis", "positive regulation of lipogenesis", "up regulation of lipid biosynthetic process", "up-regulation of lipid biosynthetic process", "upregulation of lipid biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of lipid biosynthetic process", "stimulation of lipid biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046889" ; a owl:Class ; rdfs:label "positive regulation of lipid biosynthetic process" ; rdfs:subClassOf obo:GO_0009891, obo:GO_0045834, obo:GO_0046890, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008610 ] ) ] . obo:GO_0046890 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ; oboInOwl:hasExactSynonym "regulation of lipid anabolism", "regulation of lipid biosynthesis", "regulation of lipid formation", "regulation of lipid synthesis", "regulation of lipogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046890" ; a owl:Class ; rdfs:label "regulation of lipid biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0019216, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008610 ] ) ] . obo:GO_0046903 obo:IAO_0000115 "The controlled release of a substance by a cell or a tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046903" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "secretion" ; rdfs:subClassOf obo:GO_0006810 . obo:GO_0046907 obo:IAO_0000115 "The directed movement of substances within a cell." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-18T14:04:50Z" ; oboInOwl:hasAlternativeId "GO:1902582" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism intracellular transport", "single-organism intracellular transport" ; oboInOwl:id "GO:0046907" ; a owl:Class ; rdfs:label "intracellular transport" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0051641, obo:GO_0051649, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0046928 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046928" ; a owl:Class ; rdfs:label "regulation of neurotransmitter secretion" ; rdfs:subClassOf obo:GO_0001505, obo:GO_0050804, obo:GO_0051588, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007269 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007269 ] ) ] . obo:GO_0046929 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." ; oboInOwl:hasExactSynonym "down regulation of neurotransmitter secretion", "down-regulation of neurotransmitter secretion", "downregulation of neurotransmitter secretion" ; oboInOwl:hasNarrowSynonym "conotoxin activity", "inhibition of neurotransmitter secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046929" ; a owl:Class ; rdfs:label "negative regulation of neurotransmitter secretion" ; rdfs:subClassOf obo:GO_0046928, obo:GO_0051589, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007269 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007269 ] ) ] . obo:GO_0046942 obo:IAO_0000115 "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046942" ; a owl:Class ; rdfs:label "carboxylic acid transport" ; rdfs:subClassOf obo:GO_0015711, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29067 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29067 ] ) ] . obo:GO_0046943 obo:IAO_0000115 "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-)." ; oboInOwl:hasDbXref "Reactome:R-HSA-390347" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0046943" ; a owl:Class ; rdfs:label "carboxylic acid transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0008514, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_1905039 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29067 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29067 ] ) ] . obo:GO_0046958 obo:IAO_0000115 "A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment." ; oboInOwl:hasExactSynonym "unconditional response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046958" ; a owl:Class ; rdfs:label "nonassociative learning" ; rdfs:subClassOf obo:GO_0007612 . obo:GO_0046959 obo:IAO_0000115 "A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented." ; oboInOwl:hasDbXref "Wikipedia:Habituation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046959" ; a owl:Class ; rdfs:label "habituation" ; rdfs:subClassOf obo:GO_0046958 . obo:GO_0047484 obo:IAO_0000115 "Any process that modulates the rate or extent of the response to osmotic stress." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0047484" ; a owl:Class ; rdfs:label "regulation of response to osmotic stress" ; rdfs:subClassOf obo:GO_0080134, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006970 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006970 ] ) ] . obo:GO_0047496 obo:IAO_0000115 "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." ; oboInOwl:hasExactSynonym "microtubule-based vesicle localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0047496" ; a owl:Class ; rdfs:label "vesicle transport along microtubule" ; rdfs:subClassOf obo:GO_0072384, obo:GO_0099518 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0048024 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism." ; oboInOwl:hasAlternativeId "GO:0035055" ; oboInOwl:hasBroadSynonym "regulation of pre-mRNA splicing" ; oboInOwl:hasExactSynonym "regulation of nuclear mRNA splicing, via spliceosome" ; oboInOwl:hasNarrowSynonym "regulation of nuclear mRNA splicing via U2-type spliceosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048024" ; a owl:Class ; rdfs:label "regulation of mRNA splicing, via spliceosome" ; rdfs:subClassOf obo:GO_0043484, obo:GO_0050684, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000398 ] ) ] . obo:GO_0048025 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism." ; oboInOwl:hasAlternativeId "GO:0035056" ; oboInOwl:hasBroadSynonym "negative regulation of pre-mRNA splicing" ; oboInOwl:hasExactSynonym "down regulation of nuclear mRNA splicing, via spliceosome", "down-regulation of nuclear mRNA splicing, via spliceosome", "downregulation of nuclear mRNA splicing, via spliceosome", "negative regulation of nuclear mRNA splicing, via spliceosome" ; oboInOwl:hasNarrowSynonym "down regulation of nuclear mRNA splicing via U2-type spliceosome", "down-regulation of nuclear mRNA splicing via U2-type spliceosome", "downregulation of nuclear mRNA splicing via U2-type spliceosome", "inhibition of nuclear mRNA splicing via U2-type spliceosome", "inhibition of nuclear mRNA splicing, via spliceosome", "negative regulation of nuclear mRNA splicing via U2-type spliceosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048025" ; a owl:Class ; rdfs:label "negative regulation of mRNA splicing, via spliceosome" ; rdfs:subClassOf obo:GO_0033119, obo:GO_0048024, obo:GO_0050686, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000398 ] ) ] . obo:GO_0048026 obo:IAO_0000115 "Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism." ; oboInOwl:hasAlternativeId "GO:0035057" ; oboInOwl:hasBroadSynonym "positive regulation of pre-mRNA splicing" ; oboInOwl:hasExactSynonym "positive regulation of nuclear mRNA splicing, via spliceosome", "up regulation of nuclear mRNA splicing, via spliceosome", "up-regulation of nuclear mRNA splicing, via spliceosome", "upregulation of nuclear mRNA splicing, via spliceosome" ; oboInOwl:hasNarrowSynonym "activation of nuclear mRNA splicing via U2-type spliceosome", "activation of nuclear mRNA splicing, via spliceosome", "positive regulation of nuclear mRNA splicing via U2-type spliceosome", "stimulation of nuclear mRNA splicing via U2-type spliceosome", "stimulation of nuclear mRNA splicing, via spliceosome", "up regulation of nuclear mRNA splicing via U2-type spliceosome", "up-regulation of nuclear mRNA splicing via U2-type spliceosome", "upregulation of nuclear mRNA splicing via U2-type spliceosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048026" ; a owl:Class ; rdfs:label "positive regulation of mRNA splicing, via spliceosome" ; rdfs:subClassOf obo:GO_0033120, obo:GO_0048024, obo:GO_0050685, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000398 ] ) ] . obo:GO_0048048 obo:IAO_0000115 "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048048" ; a owl:Class ; rdfs:label "embryonic eye morphogenesis" ; rdfs:subClassOf obo:GO_0048562, obo:GO_0048592 . obo:GO_0048066 obo:IAO_0000115 "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pigmentation during development" ; oboInOwl:id "GO:0048066" ; a owl:Class ; rdfs:label "developmental pigmentation" ; rdfs:subClassOf obo:GO_0043473 . obo:GO_0048070 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ; oboInOwl:hasExactSynonym "regulation of pigmentation during development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048070" ; a owl:Class ; rdfs:label "regulation of developmental pigmentation" ; rdfs:subClassOf obo:GO_0120305, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048066 ] ) ] . obo:GO_0048086 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ; oboInOwl:hasExactSynonym "down regulation of developmental pigmentation", "down-regulation of developmental pigmentation", "downregulation of developmental pigmentation" ; oboInOwl:hasNarrowSynonym "inhibition of pigmentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048086" ; a owl:Class ; rdfs:label "negative regulation of developmental pigmentation" ; rdfs:subClassOf obo:GO_0048070, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048066 ] ) ] . obo:GO_0048087 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ; oboInOwl:hasExactSynonym "up regulation of developmental pigmentation", "up-regulation of developmental pigmentation", "upregulation of developmental pigmentation" ; oboInOwl:hasNarrowSynonym "activation of developmental pigmentation", "stimulation of developmental pigmentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048087" ; a owl:Class ; rdfs:label "positive regulation of developmental pigmentation" ; rdfs:subClassOf obo:GO_0048070, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048066 ] ) ] . obo:GO_0048102 obo:IAO_0000115 "A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells." ; oboInOwl:hasBroadSynonym "autophagic death", "programmed cell death by autophagy" ; oboInOwl:hasExactSynonym "programmed cell death by macroautophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "autosis", "type II programmed cell death" ; oboInOwl:id "GO:0048102" ; a owl:Class ; rdfs:comment "The precise nature of autophagic cell death is still being debated, and the link between autophagy and cell death unclear. As autophagy is often induced under conditions of stress that could also lead to cell death, there has been a propagation of the idea that autophagy can act as a cell death mechanism; but others suggest that autophagy may simply be an attempt of dying cells to adapt to lethal stress rather than a mechanism to execute a cell death program. Further studies are required to resolve this controversy (see e.g. PMID:22082964, PMID:22052193, PMID:25236395). In the meantime, curators should carefully examine the experimental evidence presented in papers concerning autophagic cell death, and annotate accordingly. Recently, an instance of autophagic cell death, termed autosis, was discovered that relies on the plasma membrane Na+/K+-ATPase. Autosis was observed in vivo in the brain of rats subjected to an ischemic insult. It's still unclear if all cases of autophagic cell death require the Na+/K+-ATPase or not." ; rdfs:label "autophagic cell death" ; rdfs:subClassOf obo:GO_0012501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016236 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0012501 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016236 ] ) ] . obo:GO_0048103 obo:IAO_0000115 "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line." ; oboInOwl:hasExactSynonym "somatic stem cell renewal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048103" ; a owl:Class ; rdfs:label "somatic stem cell division" ; rdfs:subClassOf obo:GO_0017145, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000723 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051301 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000723 ] ) ] . obo:GO_0048132 obo:IAO_0000115 "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes." ; oboInOwl:hasAlternativeId "GO:0048141" ; oboInOwl:hasExactSynonym "female germ-line stem cell renewal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048132" ; a owl:Class ; rdfs:label "female germ-line stem cell asymmetric division" ; rdfs:subClassOf obo:GO_0098728, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048477 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_6656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000022 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_6656 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008356 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000022 ] ) ] . obo:GO_0048137 obo:IAO_0000115 "The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids." ; oboInOwl:hasExactSynonym "spermatocyte cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048137" ; a owl:Class ; rdfs:label "spermatocyte division" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0051301, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007283 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051301 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000017 ] ) ] . obo:GO_0048144 obo:IAO_0000115 "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048144" ; a owl:Class ; rdfs:label "fibroblast proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000057 ] ) ] . obo:GO_0048145 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048145" ; a owl:Class ; rdfs:label "regulation of fibroblast proliferation" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048144 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048144 ] ) ] . obo:GO_0048146 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells." ; oboInOwl:hasExactSynonym "up regulation of fibroblast proliferation", "up-regulation of fibroblast proliferation", "upregulation of fibroblast proliferation" ; oboInOwl:hasNarrowSynonym "activation of fibroblast proliferation", "stimulation of fibroblast proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048146" ; a owl:Class ; rdfs:label "positive regulation of fibroblast proliferation" ; rdfs:subClassOf obo:GO_0008284, obo:GO_0048145, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048144 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048144 ] ) ] . obo:GO_0048147 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells." ; oboInOwl:hasExactSynonym "down regulation of fibroblast proliferation", "down-regulation of fibroblast proliferation", "downregulation of fibroblast proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of fibroblast proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048147" ; a owl:Class ; rdfs:label "negative regulation of fibroblast proliferation" ; rdfs:subClassOf obo:GO_0008285, obo:GO_0048145, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048144 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048144 ] ) ] . obo:GO_0048193 obo:IAO_0000115 "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "Golgi-derived vesicle transport" ; oboInOwl:id "GO:0048193" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "Golgi vesicle transport" ; rdfs:subClassOf obo:GO_0016192, [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005798 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005798 ] ) ] . obo:GO_0048194 obo:IAO_0000115 "The evagination of the Golgi membrane, resulting in formation of a vesicle." ; oboInOwl:hasExactSynonym "Golgi-derived vesicle budding" ; oboInOwl:hasNarrowSynonym "dictyosome vesicle budding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048194" ; a owl:Class ; rdfs:label "Golgi vesicle budding" ; rdfs:subClassOf obo:GO_0006900, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048193 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0000139 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:GO_0005798 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006900 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0000139 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:GO_0005798 ] ) ] . obo:GO_0048199 obo:IAO_0000115 "The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation." ; oboInOwl:hasExactSynonym "Golgi vesicle targeting" ; oboInOwl:hasNarrowSynonym "dictyosome vesicle targeting", "vesicle targeting, to, from or within dictyosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048199" ; a owl:Class ; rdfs:label "vesicle targeting, to, from or within Golgi" ; rdfs:subClassOf obo:GO_0006903, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048193 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005794 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005798 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006903 [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005798 ] ) ] . obo:GO_0048209 obo:IAO_0000115 "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus." ; oboInOwl:hasExactSynonym "regulation of Golgi vesicle targeting" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048209" ; a owl:Class ; rdfs:label "regulation of vesicle targeting, to, from or within Golgi" ; rdfs:subClassOf obo:GO_0060341, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048199 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048199 ] ) ] . obo:GO_0048232 obo:IAO_0000115 "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048232" ; a owl:Class ; rdfs:label "male gamete generation" ; rdfs:subClassOf obo:GO_0007276 . obo:GO_0048240 obo:IAO_0000115 "A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "sperm activation" ; oboInOwl:id "GO:0048240" ; a owl:Class ; rdfs:comment "Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract." ; rdfs:label "sperm capacitation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0048469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007286 ] . obo:GO_0048243 obo:IAO_0000115 "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system." ; oboInOwl:hasExactSynonym "noradrenaline secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048243" ; a owl:Class ; rdfs:label "norepinephrine secretion" ; rdfs:subClassOf obo:GO_0015874, obo:GO_0023061, obo:GO_0050432 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0048247 obo:IAO_0000115 "The directed movement of a lymphocyte in response to an external stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048247" ; a owl:Class ; rdfs:label "lymphocyte chemotaxis" ; rdfs:subClassOf obo:GO_0030595, obo:GO_0072676 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006935 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000542 ] ) ] . obo:GO_0048251 obo:IAO_0000115 "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching." ; oboInOwl:hasExactSynonym "elastic fibre assembly", "elastin fiber assembly", "elastin fibre assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048251" ; a owl:Class ; rdfs:label "elastic fiber assembly" ; rdfs:subClassOf obo:GO_0085029, obo:GO_0097435, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0071953 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0071953 ] ) ] . obo:GO_0048259 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." ; oboInOwl:hasExactSynonym "regulation of receptor mediated endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048259" ; a owl:Class ; rdfs:label "regulation of receptor-mediated endocytosis" ; rdfs:subClassOf obo:GO_0030100, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006898 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006898 ] ) ] . obo:GO_0048260 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." ; oboInOwl:hasExactSynonym "positive regulation of receptor mediated endocytosis", "up regulation of receptor mediated endocytosis", "up-regulation of receptor mediated endocytosis", "upregulation of receptor mediated endocytosis" ; oboInOwl:hasNarrowSynonym "activation of receptor mediated endocytosis", "stimulation of receptor mediated endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048260" ; a owl:Class ; rdfs:label "positive regulation of receptor-mediated endocytosis" ; rdfs:subClassOf obo:GO_0045807, obo:GO_0048259, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006898 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006898 ] ) ] . obo:GO_0048261 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." ; oboInOwl:hasExactSynonym "down regulation of receptor mediated endocytosis", "down-regulation of receptor mediated endocytosis", "downregulation of receptor mediated endocytosis", "negative regulation of receptor mediated endocytosis" ; oboInOwl:hasNarrowSynonym "inhibition of receptor mediated endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048261" ; a owl:Class ; rdfs:label "negative regulation of receptor-mediated endocytosis" ; rdfs:subClassOf obo:GO_0045806, obo:GO_0048259, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006898 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006898 ] ) ] . obo:GO_0048280 obo:IAO_0000115 "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048280" ; a owl:Class ; rdfs:label "vesicle fusion with Golgi apparatus" ; rdfs:subClassOf obo:GO_0006906, obo:GO_0007030, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048193 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0005794 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0031982 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0048284 obo:IAO_0000115 "The creation of a single organelle from two or more organelles." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048284" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "organelle fusion" ; rdfs:subClassOf obo:GO_0006996, [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0048285 obo:IAO_0000115 "The creation of two or more organelles by division of one organelle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048285" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "organelle fission" ; rdfs:subClassOf obo:GO_0006996, [ a owl:Restriction ; owl:onProperty obo:GOREL_0002004 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:GOREL_0002004 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0048288 obo:IAO_0000115 "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear membrane fusion during karyogamy" ; oboInOwl:id "GO:0048288" ; a owl:Class ; rdfs:label "nuclear membrane fusion involved in karyogamy" ; rdfs:subClassOf obo:GO_0000740, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000741 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000740 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000741 ] ) ] . obo:GO_0048306 obo:IAO_0000115 "Binding to a protein or protein complex in the presence of calcium." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0048306" ; a owl:Class ; rdfs:label "calcium-dependent protein binding" ; rdfs:subClassOf obo:GO_0005515, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005509 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005515 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005509 ] ) ] . obo:GO_0048308 obo:IAO_0000115 "The partitioning of organelles between daughter cells at cell division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048308" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "organelle inheritance" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0048313 obo:IAO_0000115 "The partitioning of Golgi apparatus between daughter cells at cell division." ; oboInOwl:hasExactSynonym "Golgi apparatus inheritance", "Golgi division", "Golgi partitioning" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048313" ; a owl:Class ; rdfs:label "Golgi inheritance" ; rdfs:subClassOf obo:GO_0007030, obo:GO_0048308, [ a owl:Restriction ; owl:onProperty obo:GOREL_0002003 ; owl:someValuesFrom obo:GO_0005794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048308 [ a owl:Restriction ; owl:onProperty obo:GOREL_0002003 ; owl:someValuesFrom obo:GO_0005794 ] ) ] . obo:GO_0048318 obo:IAO_0000115 "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048318" ; a owl:Class ; rdfs:label "axial mesoderm development" ; rdfs:subClassOf obo:GO_0007498, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003068 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003068 ] ) ] . obo:GO_0048319 obo:IAO_0000115 "The process in which the anatomical structures of the axial mesoderm are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048319" ; a owl:Class ; rdfs:label "axial mesoderm morphogenesis" ; rdfs:subClassOf obo:GO_0048332, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048318 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003068 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003068 ] ) ] . obo:GO_0048320 obo:IAO_0000115 "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048320" ; a owl:Class ; rdfs:label "axial mesoderm formation" ; rdfs:subClassOf obo:GO_0001707, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048319 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003068 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003068 ] ) ] . obo:GO_0048332 obo:IAO_0000115 "The process in which the anatomical structures of the mesoderm are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048332" ; a owl:Class ; rdfs:label "mesoderm morphogenesis" ; rdfs:subClassOf obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007498 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000926 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000926 ] ) ] . obo:GO_0048333 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell." ; oboInOwl:hasExactSynonym "mesoderm cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048333" ; a owl:Class ; rdfs:label "mesodermal cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001707 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000222 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000222 ] ) ] . obo:GO_0048339 obo:IAO_0000115 "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048339" ; a owl:Class ; rdfs:label "paraxial mesoderm development" ; rdfs:subClassOf obo:GO_0007498, obo:GO_0060485, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003077 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003077 ] ) ] . obo:GO_0048340 obo:IAO_0000115 "The process in which the anatomical structures of the paraxial mesoderm are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048340" ; a owl:Class ; rdfs:label "paraxial mesoderm morphogenesis" ; rdfs:subClassOf obo:GO_0048332, obo:GO_0072132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048339 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003077 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003077 ] ) ] . obo:GO_0048341 obo:IAO_0000115 "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048341" ; a owl:Class ; rdfs:label "paraxial mesoderm formation" ; rdfs:subClassOf obo:GO_0001707, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048340 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003077 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003077 ] ) ] . obo:GO_0048368 obo:IAO_0000115 "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure." ; oboInOwl:hasExactSynonym "lateral plate mesoderm development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048368" ; a owl:Class ; rdfs:label "lateral mesoderm development" ; rdfs:subClassOf obo:GO_0007498, obo:GO_0060485, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003081 ] ) ] . obo:GO_0048369 obo:IAO_0000115 "The process in which the anatomical structures of the lateral mesoderm are generated and organized." ; oboInOwl:hasExactSynonym "lateral plate mesoderm morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048369" ; a owl:Class ; rdfs:label "lateral mesoderm morphogenesis" ; rdfs:subClassOf obo:GO_0048332, obo:GO_0072132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048368 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003081 ] ) ] . obo:GO_0048370 obo:IAO_0000115 "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ; oboInOwl:hasExactSynonym "lateral plate mesoderm biosynthesis", "lateral plate mesoderm formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048370" ; a owl:Class ; rdfs:label "lateral mesoderm formation" ; rdfs:subClassOf obo:GO_0001707, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048369 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003081 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003081 ] ) ] . obo:GO_0048389 obo:IAO_0000115 "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048389" ; a owl:Class ; rdfs:label "intermediate mesoderm development" ; rdfs:subClassOf obo:GO_0007498, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003064 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003064 ] ) ] . obo:GO_0048390 obo:IAO_0000115 "The process in which the anatomical structures of the intermediate mesoderm are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048390" ; a owl:Class ; rdfs:label "intermediate mesoderm morphogenesis" ; rdfs:subClassOf obo:GO_0048332, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048389 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003064 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003064 ] ) ] . obo:GO_0048391 obo:IAO_0000115 "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048391" ; a owl:Class ; rdfs:label "intermediate mesoderm formation" ; rdfs:subClassOf obo:GO_0001707, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048390 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003064 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003064 ] ) ] . obo:GO_0048468 obo:IAO_0000115 "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "terminal differentiation" ; oboInOwl:id "GO:0048468" ; oboInOwl:inSubset go:goslim_candida ; a owl:Class ; rdfs:label "cell development" ; rdfs:subClassOf obo:GO_0048856, obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030154 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000000 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000000 ] ) ] . obo:GO_0048469 obo:IAO_0000115 "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "functional differentiation" ; oboInOwl:id "GO:0048469" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cell maturation" ; rdfs:subClassOf obo:GO_0048869, obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000000 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000000 ] ) ] . obo:GO_0048477 obo:IAO_0000115 "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0009993", "GO:0048157" ; oboInOwl:hasDbXref "Wikipedia:Oogenesis" ; oboInOwl:hasExactSynonym "ovum development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048477" ; a owl:Class ; rdfs:label "oogenesis" ; rdfs:subClassOf obo:GO_0007281, obo:GO_0007292, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000025 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000025 ] ) ] . obo:GO_0048483 obo:IAO_0000115 "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048483" ; a owl:Class ; rdfs:label "autonomic nervous system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002410 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002410 ] ) ] . obo:GO_0048485 obo:IAO_0000115 "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048485" ; a owl:Class ; rdfs:label "sympathetic nervous system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048483 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000013 ] ) ] . obo:GO_0048488 obo:IAO_0000115 "A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/230"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0008099" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "synaptic vesicle retrieval" ; oboInOwl:id "GO:0048488" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle endocytosis" ; rdfs:subClassOf obo:GO_0140238, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0036465 ] . obo:GO_0048489 obo:IAO_0000115 "The directed movement of synaptic vesicles." ; oboInOwl:hasAlternativeId "GO:0016181" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "synaptic vesicle fission", "synaptic vesicle fusion", "synaptic vesicle trafficking" ; oboInOwl:id "GO:0048489" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle transport" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0051650, obo:GO_0097479 . obo:GO_0048490 obo:IAO_0000115 "The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse." ; oboInOwl:hasExactSynonym "anterograde axonal transport of synaptic vesicle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048490" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "anterograde synaptic vesicle transport" ; rdfs:subClassOf obo:GO_0008089, obo:GO_0099517 . obo:GO_0048505 obo:IAO_0000115 "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "timing of cell differentiation" ; oboInOwl:id "GO:0048505" ; a owl:Class ; rdfs:label "regulation of timing of cell differentiation" ; rdfs:subClassOf obo:GO_0040034, obo:GO_0045595 . obo:GO_0048511 obo:IAO_0000115 "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "rhythm" ; oboInOwl:id "GO:0048511" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "rhythmic process" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_131567 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_131567 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0048512 obo:IAO_0000115 "The specific behavior of an organism that recurs with a regularity of approximately 24 hours." ; oboInOwl:hasExactSynonym "circadian rhythm behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048512" ; a owl:Class ; rdfs:label "circadian behavior" ; rdfs:subClassOf obo:GO_0007622, obo:GO_0007623 . obo:GO_0048513 obo:IAO_0000115 "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ; oboInOwl:hasDbXref "Wikipedia:Organogenesis" ; oboInOwl:hasExactSynonym "development of an organ", "organogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048513" ; a owl:Class ; rdfs:label "animal organ development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000062 ] ) ] . obo:GO_0048514 obo:IAO_0000115 "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048514" ; a owl:Class ; rdfs:label "blood vessel morphogenesis" ; rdfs:subClassOf obo:GO_0035239, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001568 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001981 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001981 ] ) ] . obo:GO_0048515 obo:IAO_0000115 "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ; oboInOwl:hasExactSynonym "spermatid cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048515" ; a owl:Class ; rdfs:label "spermatid differentiation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007283 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000018 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000018 ] ) ] . obo:GO_0048518 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ; oboInOwl:hasAlternativeId "GO:0043119" ; oboInOwl:hasExactSynonym "positive regulation of physiological process", "up regulation of biological process", "up-regulation of biological process", "upregulation of biological process" ; oboInOwl:hasNarrowSynonym "activation of biological process", "stimulation of biological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048518" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of biological process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008150 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008150 ] ) ] . obo:GO_0048519 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ; oboInOwl:hasAlternativeId "GO:0043118" ; oboInOwl:hasExactSynonym "down regulation of biological process", "down-regulation of biological process", "downregulation of biological process", "negative regulation of physiological process" ; oboInOwl:hasNarrowSynonym "inhibition of biological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048519" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of biological process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008150 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008150 ] ) ] . obo:GO_0048520 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ; oboInOwl:hasExactSynonym "up regulation of behavior", "up-regulation of behavior", "upregulation of behavior" ; oboInOwl:hasNarrowSynonym "activation of behavior", "stimulation of behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048520" ; a owl:Class ; rdfs:label "positive regulation of behavior" ; rdfs:subClassOf obo:GO_0050795, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007610 ] ) ] . obo:GO_0048521 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ; oboInOwl:hasExactSynonym "down regulation of behavior", "down-regulation of behavior", "downregulation of behavior" ; oboInOwl:hasNarrowSynonym "inhibition of behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048521" ; a owl:Class ; rdfs:label "negative regulation of behavior" ; rdfs:subClassOf obo:GO_0050795, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007610 ] ) ] . obo:GO_0048522 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; oboInOwl:hasAlternativeId "GO:0051242" ; oboInOwl:hasExactSynonym "positive regulation of cellular physiological process", "up regulation of cellular process", "up-regulation of cellular process", "upregulation of cellular process" ; oboInOwl:hasNarrowSynonym "activation of cellular process", "stimulation of cellular process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048522" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of cellular process" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009987 ] ) ] . obo:GO_0048523 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; oboInOwl:hasAlternativeId "GO:0051243" ; oboInOwl:hasExactSynonym "down regulation of cellular process", "down-regulation of cellular process", "downregulation of cellular process", "negative regulation of cellular physiological process" ; oboInOwl:hasNarrowSynonym "inhibition of cellular process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048523" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of cellular process" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009987 ] ) ] . obo:GO_0048534 obo:IAO_0000115 "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." ; oboInOwl:hasExactSynonym "haematopoietic or lymphoid organ development", "haemopoietic or lymphoid organ development", "hemopoietic or lymphoid organ development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048534" ; a owl:Class ; rdfs:label "hematopoietic or lymphoid organ development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002520 ] . obo:GO_0048536 obo:IAO_0000115 "The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048536" ; a owl:Class ; rdfs:label "spleen development" ; rdfs:subClassOf obo:GO_0048534, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002106 ] ) ] . obo:GO_0048539 obo:IAO_0000115 "The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048539" ; a owl:Class ; rdfs:label "bone marrow development" ; rdfs:subClassOf obo:GO_0009888, obo:GO_0048534, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060348 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002371 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002371 ] ) ] . obo:GO_0048540 obo:IAO_0000115 "The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048540" ; a owl:Class ; rdfs:label "bursa of Fabricius development" ; rdfs:subClassOf obo:GO_0048534 . obo:GO_0048545 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." ; oboInOwl:hasExactSynonym "response to steroid hormone stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048545" ; a owl:Class ; rdfs:label "response to steroid hormone" ; rdfs:subClassOf obo:GO_0009725, obo:GO_0014070, obo:GO_0033993, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_26764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_26764 ] ) ] . obo:GO_0048546 obo:IAO_0000115 "The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed." ; oboInOwl:hasAlternativeId "GO:0048547" ; oboInOwl:hasBroadSynonym "gut morphogenesis" ; oboInOwl:hasExactSynonym "alimentary canal morphogenesis", "digestive tube morphogenesis", "gastrointestinal tract morphogenesis" ; oboInOwl:hasNarrowSynonym "intestinal morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048546" ; a owl:Class ; rdfs:label "digestive tract morphogenesis" ; rdfs:subClassOf obo:GO_0035239, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048565 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001555 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001555 ] ) ] . obo:GO_0048562 obo:IAO_0000115 "Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048562" ; a owl:Class ; rdfs:label "embryonic organ morphogenesis" ; rdfs:subClassOf obo:GO_0009887, obo:GO_0048598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048568 ] . obo:GO_0048565 obo:IAO_0000115 "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." ; oboInOwl:hasBroadSynonym "gut development" ; oboInOwl:hasNarrowSynonym "intestinal development", "intestine development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048565" ; a owl:Class ; rdfs:label "digestive tract development" ; rdfs:subClassOf obo:GO_0035295, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055123 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001555 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001555 ] ) ] . obo:GO_0048568 obo:IAO_0000115 "Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ; oboInOwl:hasExactSynonym "embryonic organogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048568" ; a owl:Class ; rdfs:label "embryonic organ development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000062 ] ) ] . obo:GO_0048569 obo:IAO_0000115 "Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ; oboInOwl:hasExactSynonym "post-embryonic animal organogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048569" ; a owl:Class ; rdfs:label "post-embryonic animal organ development" ; rdfs:subClassOf obo:GO_0048513 . obo:GO_0048570 obo:IAO_0000115 "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048570" ; a owl:Class ; rdfs:label "notochord morphogenesis" ; rdfs:subClassOf obo:GO_0048562, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030903 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002328 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002328 ] ) ] . obo:GO_0048580 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048580" ; a owl:Class ; rdfs:label "regulation of post-embryonic development" ; rdfs:subClassOf obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009791 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009791 ] ) ] . obo:GO_0048581 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ; oboInOwl:hasExactSynonym "down regulation of post-embryonic development", "down-regulation of post-embryonic development", "downregulation of post-embryonic development" ; oboInOwl:hasNarrowSynonym "inhibition of post-embryonic development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048581" ; a owl:Class ; rdfs:label "negative regulation of post-embryonic development" ; rdfs:subClassOf obo:GO_0048580, obo:GO_0051093, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009791 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009791 ] ) ] . obo:GO_0048582 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ; oboInOwl:hasExactSynonym "up regulation of post-embryonic development", "up-regulation of post-embryonic development", "upregulation of post-embryonic development" ; oboInOwl:hasNarrowSynonym "activation of post-embryonic development", "stimulation of post-embryonic development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048582" ; a owl:Class ; rdfs:label "positive regulation of post-embryonic development" ; rdfs:subClassOf obo:GO_0048580, obo:GO_0051094, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009791 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009791 ] ) ] . obo:GO_0048583 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048583" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "regulation of response to stimulus" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050896 ] ) ] . obo:GO_0048584 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to stimulus", "up-regulation of response to stimulus", "upregulation of response to stimulus" ; oboInOwl:hasNarrowSynonym "activation of response to stimulus", "stimulation of response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048584" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "positive regulation of response to stimulus" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050896 ] ) ] . obo:GO_0048585 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to stimulus", "down-regulation of response to stimulus", "downregulation of response to stimulus" ; oboInOwl:hasNarrowSynonym "inhibition of response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048585" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "negative regulation of response to stimulus" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050896 ] ) ] . obo:GO_0048588 obo:IAO_0000115 "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." ; oboInOwl:hasExactSynonym "developmental growth of a unicellular organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048588" ; a owl:Class ; rdfs:label "developmental cell growth" ; rdfs:subClassOf obo:GO_0016049, obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ] . obo:GO_0048589 obo:IAO_0000115 "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048589" ; a owl:Class ; rdfs:label "developmental growth" ; rdfs:subClassOf obo:GO_0040007, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032502 ] ) ] . obo:GO_0048592 obo:IAO_0000115 "The process in which the anatomical structures of the eye are generated and organized." ; oboInOwl:hasAlternativeId "GO:0048748" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048592" ; a owl:Class ; rdfs:label "eye morphogenesis" ; rdfs:subClassOf obo:GO_0090596, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001654 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000970 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000970 ] ) ] . obo:GO_0048593 obo:IAO_0000115 "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field." ; oboInOwl:hasAlternativeId "GO:0048594", "GO:0048595" ; oboInOwl:hasExactSynonym "camera-style eye morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048593" ; a owl:Class ; rdfs:label "camera-type eye morphogenesis" ; rdfs:subClassOf obo:GO_0048592, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043010 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000019 ] ) ] . obo:GO_0048596 obo:IAO_0000115 "The process in which the anatomical structures of the eye are generated and organized during embryonic development." ; oboInOwl:hasBroadSynonym "embryonic eye morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048596" ; a owl:Class ; rdfs:label "embryonic camera-type eye morphogenesis" ; rdfs:subClassOf obo:GO_0048048, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031076 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048593 ] . obo:GO_0048598 obo:IAO_0000115 "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." ; oboInOwl:hasAlternativeId "GO:0048828" ; oboInOwl:hasExactSynonym "embryonic anatomical structure morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048598" ; a owl:Class ; rdfs:label "embryonic morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ] . obo:GO_0048599 obo:IAO_0000115 "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048599" ; a owl:Class ; rdfs:label "oocyte development" ; rdfs:subClassOf obo:GO_0007281, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009994 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000023 ] ) ] . obo:GO_0048601 obo:IAO_0000115 "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte." ; oboInOwl:hasExactSynonym "oocyte morphogenesis during differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048601" ; a owl:Class ; rdfs:label "oocyte morphogenesis" ; rdfs:subClassOf obo:GO_0000904, obo:GO_0003006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048599 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_0000023 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:CL_0000023 ] ) ] . obo:GO_0048608 obo:IAO_0000115 "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23445"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048608" ; a owl:Class ; rdfs:label "reproductive structure development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061458 ] . obo:GO_0048609 obo:IAO_0000115 "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." ; oboInOwl:hasBroadSynonym "organismal reproductive process" ; oboInOwl:hasExactSynonym "reproductive process in a multicellular organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048609" ; a owl:Class ; rdfs:label "multicellular organismal reproductive process" ; rdfs:subClassOf obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] . obo:GO_0048627 obo:IAO_0000115 "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048627" ; a owl:Class ; rdfs:label "myoblast development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045445 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000056 ] ) ] . obo:GO_0048628 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048628" ; a owl:Class ; rdfs:label "myoblast maturation" ; rdfs:subClassOf obo:GO_0048469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048627 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000056 ] ) ] . obo:GO_0048630 obo:IAO_0000115 "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048630" ; a owl:Class ; rdfs:label "skeletal muscle tissue growth" ; rdfs:subClassOf obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007519 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0001134 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0001134 ] ) ] . obo:GO_0048631 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of skeletal muscle growth." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048631" ; a owl:Class ; rdfs:label "regulation of skeletal muscle tissue growth" ; rdfs:subClassOf obo:GO_0048638, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048630 ] ) ] . obo:GO_0048632 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth." ; oboInOwl:hasExactSynonym "down regulation of skeletal muscle growth", "down-regulation of skeletal muscle growth", "downregulation of skeletal muscle growth" ; oboInOwl:hasNarrowSynonym "inhibition of skeletal muscle growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048632" ; a owl:Class ; rdfs:label "negative regulation of skeletal muscle tissue growth" ; rdfs:subClassOf obo:GO_0048631, obo:GO_0048640, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048630 ] ) ] . obo:GO_0048633 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of skeletal muscle growth." ; oboInOwl:hasExactSynonym "up regulation of skeletal muscle growth", "up-regulation of skeletal muscle growth", "upregulation of skeletal muscle growth" ; oboInOwl:hasNarrowSynonym "activation of skeletal muscle growth", "stimulation of skeletal muscle growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048633" ; a owl:Class ; rdfs:label "positive regulation of skeletal muscle tissue growth" ; rdfs:subClassOf obo:GO_0048631, obo:GO_0048639, obo:GO_0048643, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048630 ] ) ] . obo:GO_0048634 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of muscle development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048634" ; a owl:Class ; rdfs:label "regulation of muscle organ development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007517 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007517 ] ) ] . obo:GO_0048635 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." ; oboInOwl:hasExactSynonym "down regulation of muscle development", "down-regulation of muscle development", "downregulation of muscle development" ; oboInOwl:hasNarrowSynonym "inhibition of muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048635" ; a owl:Class ; rdfs:label "negative regulation of muscle organ development" ; rdfs:subClassOf obo:GO_0048634, obo:GO_0051093, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007517 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007517 ] ) ] . obo:GO_0048636 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of muscle development." ; oboInOwl:hasExactSynonym "up regulation of muscle development", "up-regulation of muscle development", "upregulation of muscle development" ; oboInOwl:hasNarrowSynonym "activation of muscle development", "stimulation of muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048636" ; a owl:Class ; rdfs:label "positive regulation of muscle organ development" ; rdfs:subClassOf obo:GO_0048634, obo:GO_0051094, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007517 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007517 ] ) ] . obo:GO_0048638 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of developmental growth." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048638" ; a owl:Class ; rdfs:label "regulation of developmental growth" ; rdfs:subClassOf obo:GO_0040008, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048589 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048589 ] ) ] . obo:GO_0048639 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of developmental growth." ; oboInOwl:hasExactSynonym "up regulation of developmental growth", "up-regulation of developmental growth", "upregulation of developmental growth" ; oboInOwl:hasNarrowSynonym "activation of developmental growth", "stimulation of developmental growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048639" ; a owl:Class ; rdfs:label "positive regulation of developmental growth" ; rdfs:subClassOf obo:GO_0045927, obo:GO_0048638, obo:GO_0051094, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048589 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048589 ] ) ] . obo:GO_0048640 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." ; oboInOwl:hasExactSynonym "down regulation of developmental growth", "down-regulation of developmental growth", "downregulation of developmental growth" ; oboInOwl:hasNarrowSynonym "inhibition of developmental growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048640" ; a owl:Class ; rdfs:label "negative regulation of developmental growth" ; rdfs:subClassOf obo:GO_0045926, obo:GO_0048638, obo:GO_0051093, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048589 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048589 ] ) ] . obo:GO_0048641 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048641" ; a owl:Class ; rdfs:label "regulation of skeletal muscle tissue development" ; rdfs:subClassOf obo:GO_0016202, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007519 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007519 ] ) ] . obo:GO_0048642 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development." ; oboInOwl:hasExactSynonym "down regulation of skeletal muscle development", "down-regulation of skeletal muscle development", "downregulation of skeletal muscle development" ; oboInOwl:hasNarrowSynonym "inhibition of skeletal muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048642" ; a owl:Class ; rdfs:label "negative regulation of skeletal muscle tissue development" ; rdfs:subClassOf obo:GO_0045843, obo:GO_0048641, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007519 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007519 ] ) ] . obo:GO_0048643 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of skeletal muscle tissue development." ; oboInOwl:hasExactSynonym "up regulation of skeletal muscle development", "up-regulation of skeletal muscle development", "upregulation of skeletal muscle development" ; oboInOwl:hasNarrowSynonym "activation of skeletal muscle development", "stimulation of skeletal muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048643" ; a owl:Class ; rdfs:label "positive regulation of skeletal muscle tissue development" ; rdfs:subClassOf obo:GO_0045844, obo:GO_0048641, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007519 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007519 ] ) ] . obo:GO_0048644 obo:IAO_0000115 "The process in which the anatomical structures of muscle are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048644" ; a owl:Class ; rdfs:label "muscle organ morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007517 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001630 ] ) ] . obo:GO_0048645 obo:IAO_0000115 "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ." ; oboInOwl:hasNarrowSynonym "animal organ primordium initiation", "initiation of an animal organ primordium" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048645" ; a owl:Class ; rdfs:label "animal organ formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009887 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003103 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003103 ] ) ] . obo:GO_0048646 obo:IAO_0000115 "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ; oboInOwl:hasExactSynonym "formation of an anatomical structure involved in morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048646" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:comment "Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense." ; rdfs:label "anatomical structure formation involved in morphogenesis" ; rdfs:subClassOf obo:GO_0032502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] . obo:GO_0048659 obo:IAO_0000115 "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population." ; oboInOwl:hasExactSynonym "SMC proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048659" ; a owl:Class ; rdfs:label "smooth muscle cell proliferation" ; rdfs:subClassOf obo:GO_0033002, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000192 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000192 ] ) ] . obo:GO_0048660 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation." ; oboInOwl:hasExactSynonym "regulation of SMC proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048660" ; a owl:Class ; rdfs:label "regulation of smooth muscle cell proliferation" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048659 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048659 ] ) ] . obo:GO_0048661 obo:IAO_0000115 "Any process that activates or increases the rate or extent of smooth muscle cell proliferation." ; oboInOwl:hasExactSynonym "positive regulation of SMC proliferation", "up regulation of smooth muscle cell proliferation", "up-regulation of smooth muscle cell proliferation", "upregulation of smooth muscle cell proliferation" ; oboInOwl:hasNarrowSynonym "activation of smooth muscle cell proliferation", "stimulation of smooth muscle cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048661" ; a owl:Class ; rdfs:label "positive regulation of smooth muscle cell proliferation" ; rdfs:subClassOf obo:GO_0008284, obo:GO_0048660, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048659 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048659 ] ) ] . obo:GO_0048662 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation." ; oboInOwl:hasExactSynonym "down regulation of smooth muscle cell proliferation", "down-regulation of smooth muscle cell proliferation", "downregulation of smooth muscle cell proliferation", "negative regulation of SMC proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of smooth muscle cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048662" ; a owl:Class ; rdfs:label "negative regulation of smooth muscle cell proliferation" ; rdfs:subClassOf obo:GO_0008285, obo:GO_0048660, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048659 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048659 ] ) ] . obo:GO_0048666 obo:IAO_0000115 "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048666" ; a owl:Class ; rdfs:label "neuron development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030182 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000540 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0048667 obo:IAO_0000115 "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." ; oboInOwl:hasExactSynonym "neuron morphogenesis involved in differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048667" ; a owl:Class ; rdfs:label "cell morphogenesis involved in neuron differentiation" ; rdfs:subClassOf obo:GO_0000904, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000902 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030182 ] ) ] . obo:GO_0048675 obo:IAO_0000115 "Long distance growth of a single axon process involved in cellular development." ; oboInOwl:hasAlternativeId "GO:0048676" ; oboInOwl:hasExactSynonym "axon extension involved in development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048675" ; a owl:Class ; rdfs:label "axon extension" ; rdfs:subClassOf obo:GO_1990138, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007409 ] . obo:GO_0048699 obo:IAO_0000115 "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." ; oboInOwl:hasExactSynonym "neuron generation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048699" ; a owl:Class ; rdfs:label "generation of neurons" ; rdfs:subClassOf obo:GO_0022008 . obo:GO_0048705 obo:IAO_0000115 "The process in which the anatomical structures of the skeleton are generated and organized." ; oboInOwl:hasExactSynonym "skeletal morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048705" ; a owl:Class ; rdfs:label "skeletal system morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001501 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001434 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001434 ] ) ] . obo:GO_0048729 obo:IAO_0000115 "The process in which the anatomical structures of a tissue are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048729" ; a owl:Class ; rdfs:label "tissue morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009888 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000479 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000479 ] ) ] . obo:GO_0048730 obo:IAO_0000115 "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "hypodermis morphogenesis" ; oboInOwl:id "GO:0048730" ; a owl:Class ; rdfs:label "epidermis morphogenesis" ; rdfs:subClassOf obo:GO_0002009, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008544 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007376 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007376 ] ) ] . obo:GO_0048731 obo:IAO_0000115 "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048731" ; oboInOwl:inSubset go:goslim_mouse ; a owl:Class ; rdfs:label "system development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000467 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000467 ] ) ] . obo:GO_0048732 obo:IAO_0000115 "The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048732" ; a owl:Class ; rdfs:label "gland development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002530 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002530 ] ) ] . obo:GO_0048736 obo:IAO_0000115 "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048736" ; a owl:Class ; rdfs:label "appendage development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000026 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000026 ] ) ] . obo:GO_0048738 obo:IAO_0000115 "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure." ; oboInOwl:hasExactSynonym "heart muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048738" ; a owl:Class ; rdfs:label "cardiac muscle tissue development" ; rdfs:subClassOf obo:GO_0014706, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001133 ] ) ] . obo:GO_0048741 obo:IAO_0000115 "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." ; oboInOwl:hasExactSynonym "skeletal muscle fibre development", "skeletal myofiber development", "skeletal myofibre development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048741" ; a owl:Class ; rdfs:label "skeletal muscle fiber development" ; rdfs:subClassOf obo:GO_0014904, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007519 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0008002 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0008002 ] ) ] . obo:GO_0048742 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." ; oboInOwl:hasExactSynonym "regulation of skeletal muscle fibre development", "regulation of skeletal myofiber development", "regulation of skeletal myofibre development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048742" ; a owl:Class ; rdfs:label "regulation of skeletal muscle fiber development" ; rdfs:subClassOf obo:GO_0010830, obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048741 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048741 ] ) ] . obo:GO_0048743 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." ; oboInOwl:hasExactSynonym "positive regulation of skeletal muscle fibre development", "positive regulation of skeletal myofiber development", "positive regulation of skeletal myofibre development", "up regulation of skeletal muscle fiber development", "up-regulation of skeletal muscle fiber development", "upregulation of skeletal muscle fiber development" ; oboInOwl:hasNarrowSynonym "activation of skeletal muscle fiber development", "stimulation of skeletal muscle fiber development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048743" ; a owl:Class ; rdfs:label "positive regulation of skeletal muscle fiber development" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0048643, obo:GO_0048742, obo:GO_0051155, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048741 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048741 ] ) ] . obo:GO_0048744 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast." ; oboInOwl:hasExactSynonym "down regulation of skeletal muscle fiber development", "down-regulation of skeletal muscle fiber development", "downregulation of skeletal muscle fiber development", "negative regulation of skeletal muscle fibre development", "negative regulation of skeletal myofiber development", "negative regulation of skeletal myofibre development" ; oboInOwl:hasNarrowSynonym "inhibition of skeletal muscle fiber development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048744" ; a owl:Class ; rdfs:label "negative regulation of skeletal muscle fiber development" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0048742, obo:GO_0051154, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048741 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048741 ] ) ] . obo:GO_0048745 obo:IAO_0000115 "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048745" ; a owl:Class ; rdfs:label "smooth muscle tissue development" ; rdfs:subClassOf obo:GO_0060537, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001135 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001135 ] ) ] . obo:GO_0048749 obo:IAO_0000115 "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye." ; oboInOwl:hasAlternativeId "GO:0007456" ; oboInOwl:hasExactSynonym "insect-type retina development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048749" ; a owl:Class ; rdfs:label "compound eye development" ; rdfs:subClassOf obo:GO_0001654, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000018 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000018 ] ) ] . obo:GO_0048753 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule." ; oboInOwl:hasExactSynonym "pigment granule organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pigment granule organization and biogenesis" ; oboInOwl:id "GO:0048753" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "pigment granule organization" ; rdfs:subClassOf obo:GO_0016050, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033059 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0048770 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0048770 ] ) ] . obo:GO_0048754 obo:IAO_0000115 "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "tubulogenesis" ; oboInOwl:id "GO:0048754" ; a owl:Class ; rdfs:label "branching morphogenesis of an epithelial tube" ; rdfs:subClassOf obo:GO_0035239, obo:GO_0061138, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060562 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001763 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000025 ] ) ] . obo:GO_0048755 obo:IAO_0000115 "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048755" ; a owl:Class ; rdfs:label "branching morphogenesis of a nerve" ; rdfs:subClassOf obo:GO_0001763, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001021 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001763 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001021 ] ) ] . obo:GO_0048762 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048762" ; a owl:Class ; rdfs:label "mesenchymal cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060485 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0008019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0008019 ] ) ] . obo:GO_0048770 obo:IAO_0000115 "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0048770" ; a owl:Class ; rdfs:label "pigment granule" ; rdfs:subClassOf obo:GO_0031410 . obo:GO_0048786 obo:IAO_0000115 "A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix." ; oboInOwl:hasDbXref "NIF_Subcellular:sao792027222" ; oboInOwl:hasExactSynonym "pre-synaptic active zone", "presynaptic specialization" ; oboInOwl:hasNarrowSynonym "pre-synaptic active zone component" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0048786" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic active zone" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] . obo:GO_0048793 obo:IAO_0000115 "The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." ; oboInOwl:hasExactSynonym "pronephric kidney development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048793" ; a owl:Class ; rdfs:label "pronephros development" ; rdfs:subClassOf obo:GO_0001822, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002120 ] ) ] . obo:GO_0048799 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048799" ; a owl:Class ; rdfs:label "animal organ maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048513 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000062 ] ) ] . obo:GO_0048806 obo:IAO_0000115 "The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure." ; oboInOwl:hasExactSynonym "genital development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048806" ; a owl:Class ; rdfs:label "genitalia development" ; rdfs:subClassOf obo:GO_0048513, obo:GO_0048608, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007548 ] . obo:GO_0048808 obo:IAO_0000115 "The process in which the anatomical structures of male genitalia are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "male genital morphogenesis" ; oboInOwl:id "GO:0048808" ; a owl:Class ; rdfs:label "male genitalia morphogenesis" ; rdfs:subClassOf obo:GO_0035112, obo:GO_0090598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030539 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000079 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000079 ] ) ] . obo:GO_0048812 obo:IAO_0000115 "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." ; oboInOwl:hasNarrowSynonym "neurite biosynthesis", "neurite formation", "neurite growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neurite morphogenesis" ; oboInOwl:id "GO:0048812" ; a owl:Class ; rdfs:label "neuron projection morphogenesis" ; rdfs:subClassOf obo:GO_0120039, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031175 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0043005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0043005 ] ) ] . obo:GO_0048813 obo:IAO_0000115 "The process in which the anatomical structures of a dendrite are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048813" ; a owl:Class ; rdfs:label "dendrite morphogenesis" ; rdfs:subClassOf obo:GO_0048812, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016358 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048667 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0030425 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0030425 ] ) ] . obo:GO_0048814 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of dendrite morphogenesis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048814" ; a owl:Class ; rdfs:label "regulation of dendrite morphogenesis" ; rdfs:subClassOf obo:GO_0022603, obo:GO_0050773, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048813 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048813 ] ) ] . obo:GO_0048821 obo:IAO_0000115 "The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure." ; oboInOwl:hasExactSynonym "RBC development", "red blood cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048821" ; a owl:Class ; rdfs:label "erythrocyte development" ; rdfs:subClassOf obo:GO_0061515, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030218 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000232 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000232 ] ) ] . obo:GO_0048822 obo:IAO_0000115 "The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ; oboInOwl:hasExactSynonym "enucleate RBC development", "enucleate red blood cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048822" ; a owl:Class ; rdfs:label "enucleate erythrocyte development" ; rdfs:subClassOf obo:GO_0048821, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043353 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000595 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000595 ] ) ] . obo:GO_0048823 obo:IAO_0000115 "The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ; oboInOwl:hasExactSynonym "nucleate RBC development", "nucleate red blood cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048823" ; a owl:Class ; rdfs:label "nucleate erythrocyte development" ; rdfs:subClassOf obo:GO_0048821, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043363 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000562 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000562 ] ) ] . obo:GO_0048841 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048841" ; a owl:Class ; rdfs:label "regulation of axon extension involved in axon guidance" ; rdfs:subClassOf obo:GO_0030516, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048846 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048846 ] ) ] . obo:GO_0048842 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance." ; oboInOwl:hasExactSynonym "up regulation of axon extension involved in axon guidance", "up-regulation of axon extension involved in axon guidance", "upregulation of axon extension involved in axon guidance" ; oboInOwl:hasNarrowSynonym "activation of axon extension involved in axon guidance", "stimulation of axon extension involved in axon guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048842" ; a owl:Class ; rdfs:label "positive regulation of axon extension involved in axon guidance" ; rdfs:subClassOf obo:GO_0045773, obo:GO_0048841, obo:GO_0050921, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048846 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048846 ] ) ] . obo:GO_0048843 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance." ; oboInOwl:hasExactSynonym "down regulation of axon extension involved in axon guidance", "down-regulation of axon extension involved in axon guidance", "downregulation of axon extension involved in axon guidance" ; oboInOwl:hasNarrowSynonym "inhibition of axon extension involved in axon guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048843" ; a owl:Class ; rdfs:label "negative regulation of axon extension involved in axon guidance" ; rdfs:subClassOf obo:GO_0030517, obo:GO_0048841, obo:GO_0050922, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048846 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048846 ] ) ] . obo:GO_0048844 obo:IAO_0000115 "The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs." ; oboInOwl:hasExactSynonym "arterial morphogenesis", "arteriogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048844" ; a owl:Class ; rdfs:label "artery morphogenesis" ; rdfs:subClassOf obo:GO_0048514, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060840 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001637 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001637 ] ) ] . obo:GO_0048845 obo:IAO_0000115 "The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart." ; oboInOwl:hasBroadSynonym "vein morphogenesis" ; oboInOwl:hasExactSynonym "venous morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048845" ; a owl:Class ; rdfs:label "venous blood vessel morphogenesis" ; rdfs:subClassOf obo:GO_0048514, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060841 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001638 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001638 ] ) ] . obo:GO_0048846 obo:IAO_0000115 "The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048846" ; a owl:Class ; rdfs:label "axon extension involved in axon guidance" ; rdfs:subClassOf obo:GO_0048675, obo:GO_1902284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048675 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ] ) ] . obo:GO_0048854 obo:IAO_0000115 "The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048854" ; a owl:Class ; rdfs:label "brain morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007420 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000955 ] ) ] . obo:GO_0048856 obo:IAO_0000115 "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ; oboInOwl:hasExactSynonym "development of an anatomical structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048856" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic, go:goslim_plant ; a owl:Class ; rdfs:label "anatomical structure development" ; rdfs:subClassOf obo:GO_0032502, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000061 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000061 ] ) ] . obo:GO_0048857 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048857" ; a owl:Class ; rdfs:label "neural nucleus development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000125 ] ) ] . obo:GO_0048858 obo:IAO_0000115 "The process in which the anatomical structures of a cell projection are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048858" ; a owl:Class ; rdfs:label "cell projection morphogenesis" ; rdfs:subClassOf obo:GO_0030030, obo:GO_0032990, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0042995 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0042995 ] ) ] . obo:GO_0048859 obo:IAO_0000115 "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048859" ; a owl:Class ; rdfs:label "formation of anatomical boundary" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0007651 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0007651 ] ) ] . obo:GO_0048863 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ; oboInOwl:hasDbXref "Wikipedia:Stem_cell_differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048863" ; a owl:Class ; rdfs:label "stem cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000034 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000034 ] ) ] . obo:GO_0048864 obo:IAO_0000115 "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048864" ; a owl:Class ; rdfs:label "stem cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048863 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000034 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000034 ] ) ] . obo:GO_0048869 obo:IAO_0000115 "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048869" ; a owl:Class ; rdfs:label "cellular developmental process" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0032502 . obo:GO_0048870 obo:IAO_0000115 "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI ; oboInOwl:hasExactSynonym "cell locomotion", "movement of a cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell movement" ; oboInOwl:id "GO:0048870" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "cell motility" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0048871 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state at the level of the multicellular organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048871" ; a owl:Class ; rdfs:label "multicellular organismal-level homeostasis" ; rdfs:subClassOf obo:GO_0032501, obo:GO_0042592 . obo:GO_0048872 obo:IAO_0000115 "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24218"^^xsd:anyURI ; oboInOwl:hasExactSynonym "cell population homeostasis", "homeostasis of cell number" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048872" ; a owl:Class ; rdfs:label "homeostasis of number of cells" ; rdfs:subClassOf obo:GO_0048871 . obo:GO_0048878 obo:IAO_0000115 "Any biological process involved in the maintenance of an internal steady state of a chemical." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048878" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "chemical homeostasis" ; rdfs:subClassOf obo:GO_0042592, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_24431 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042592 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_24431 ] ) ] . obo:GO_0048880 obo:IAO_0000115 "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048880" ; a owl:Class ; rdfs:label "sensory system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001032 ] ) ] . obo:GO_0048934 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048934" ; a owl:Class ; rdfs:label "peripheral nervous system neuron differentiation" ; rdfs:subClassOf obo:GO_0030182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007422 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_2000032 ] ) ] . obo:GO_0048935 obo:IAO_0000115 "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048935" ; a owl:Class ; rdfs:label "peripheral nervous system neuron development" ; rdfs:subClassOf obo:GO_0048666, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048934 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_2000032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_2000032 ] ) ] . obo:GO_0050000 obo:IAO_0000115 "Any process in which a chromosome is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "chromosome localisation", "establishment and maintenance of chromosome localization", "establishment and maintenance of chromosome position" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050000" ; a owl:Class ; rdfs:label "chromosome localization" ; rdfs:subClassOf obo:GO_0051640, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005694 ] ) ] . obo:GO_0050432 obo:IAO_0000115 "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050432" ; a owl:Class ; rdfs:label "catecholamine secretion" ; rdfs:subClassOf obo:GO_0032940, obo:GO_0051937 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33567 ] ) ] . obo:GO_0050433 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050433" ; a owl:Class ; rdfs:label "regulation of catecholamine secretion" ; rdfs:subClassOf obo:GO_0051952, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050432 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050432 ] ) ] . obo:GO_0050657 obo:IAO_0000115 "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050657" ; a owl:Class ; rdfs:label "nucleic acid transport" ; rdfs:subClassOf obo:GO_0015931, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33696 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33696 ] ) ] . obo:GO_0050658 obo:IAO_0000115 "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050658" ; a owl:Class ; rdfs:label "RNA transport" ; rdfs:subClassOf obo:GO_0050657, obo:GO_0051236, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33697 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33697 ] ) ] . obo:GO_0050670 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of lymphocyte proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050670" ; a owl:Class ; rdfs:label "regulation of lymphocyte proliferation" ; rdfs:subClassOf obo:GO_0032944, obo:GO_0051249, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046651 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046651 ] ) ] . obo:GO_0050671 obo:IAO_0000115 "Any process that activates or increases the rate or extent of lymphocyte proliferation." ; oboInOwl:hasExactSynonym "up regulation of lymphocyte proliferation", "up-regulation of lymphocyte proliferation", "upregulation of lymphocyte proliferation" ; oboInOwl:hasNarrowSynonym "activation of lymphocyte proliferation", "stimulation of lymphocyte proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050671" ; a owl:Class ; rdfs:label "positive regulation of lymphocyte proliferation" ; rdfs:subClassOf obo:GO_0032946, obo:GO_0050670, obo:GO_0051251, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046651 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046651 ] ) ] . obo:GO_0050672 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation." ; oboInOwl:hasExactSynonym "down regulation of lymphocyte proliferation", "down-regulation of lymphocyte proliferation", "downregulation of lymphocyte proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of lymphocyte proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050672" ; a owl:Class ; rdfs:label "negative regulation of lymphocyte proliferation" ; rdfs:subClassOf obo:GO_0032945, obo:GO_0050670, obo:GO_0051250, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046651 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046651 ] ) ] . obo:GO_0050673 obo:IAO_0000115 "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050673" ; a owl:Class ; rdfs:label "epithelial cell proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000066 ] ) ] . obo:GO_0050678 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of epithelial cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050678" ; a owl:Class ; rdfs:label "regulation of epithelial cell proliferation" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050673 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050673 ] ) ] . obo:GO_0050679 obo:IAO_0000115 "Any process that activates or increases the rate or extent of epithelial cell proliferation." ; oboInOwl:hasExactSynonym "up regulation of epithelial cell proliferation", "up-regulation of epithelial cell proliferation", "upregulation of epithelial cell proliferation" ; oboInOwl:hasNarrowSynonym "activation of epithelial cell proliferation", "stimulation of epithelial cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050679" ; a owl:Class ; rdfs:label "positive regulation of epithelial cell proliferation" ; rdfs:subClassOf obo:GO_0008284, obo:GO_0050678, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050673 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050673 ] ) ] . obo:GO_0050680 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation." ; oboInOwl:hasExactSynonym "down regulation of epithelial cell proliferation", "down-regulation of epithelial cell proliferation", "downregulation of epithelial cell proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of epithelial cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050680" ; a owl:Class ; rdfs:label "negative regulation of epithelial cell proliferation" ; rdfs:subClassOf obo:GO_0008285, obo:GO_0050678, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050673 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050673 ] ) ] . obo:GO_0050684 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050684" ; a owl:Class ; rdfs:label "regulation of mRNA processing" ; rdfs:subClassOf obo:GO_1903311, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006397 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006397 ] ) ] . obo:GO_0050685 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mRNA processing." ; oboInOwl:hasExactSynonym "up regulation of mRNA processing", "up-regulation of mRNA processing", "upregulation of mRNA processing" ; oboInOwl:hasNarrowSynonym "activation of mRNA processing", "stimulation of mRNA processing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050685" ; a owl:Class ; rdfs:label "positive regulation of mRNA processing" ; rdfs:subClassOf obo:GO_0050684, obo:GO_1903313, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006397 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006397 ] ) ] . obo:GO_0050686 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing." ; oboInOwl:hasExactSynonym "down regulation of mRNA processing", "down-regulation of mRNA processing", "downregulation of mRNA processing" ; oboInOwl:hasNarrowSynonym "inhibition of mRNA processing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050686" ; a owl:Class ; rdfs:label "negative regulation of mRNA processing" ; rdfs:subClassOf obo:GO_0050684, obo:GO_1903312, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006397 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006397 ] ) ] . obo:GO_0050708 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050708" ; a owl:Class ; rdfs:label "regulation of protein secretion" ; rdfs:subClassOf obo:GO_0051223, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009306 ] ) ] . obo:GO_0050709 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." ; oboInOwl:hasExactSynonym "down regulation of protein secretion", "down-regulation of protein secretion", "downregulation of protein secretion" ; oboInOwl:hasNarrowSynonym "inhibition of protein secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050709" ; a owl:Class ; rdfs:label "negative regulation of protein secretion" ; rdfs:subClassOf obo:GO_0050708, obo:GO_0051224, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009306 ] ) ] . obo:GO_0050714 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." ; oboInOwl:hasExactSynonym "up regulation of protein secretion", "up-regulation of protein secretion", "upregulation of protein secretion" ; oboInOwl:hasNarrowSynonym "activation of protein secretion", "stimulation of protein secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050714" ; a owl:Class ; rdfs:label "positive regulation of protein secretion" ; rdfs:subClassOf obo:GO_0050708, obo:GO_0051222, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009306 ] ) ] . obo:GO_0050727 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050727" ; a owl:Class ; rdfs:label "regulation of inflammatory response" ; rdfs:subClassOf obo:GO_0031347, obo:GO_0032101, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006954 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006954 ] ) ] . obo:GO_0050728 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response." ; oboInOwl:hasAlternativeId "GO:0030236" ; oboInOwl:hasExactSynonym "anti-inflammatory response", "down regulation of inflammatory response", "down-regulation of inflammatory response", "downregulation of inflammatory response" ; oboInOwl:hasNarrowSynonym "inhibition of inflammatory response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050728" ; a owl:Class ; rdfs:label "negative regulation of inflammatory response" ; rdfs:subClassOf obo:GO_0031348, obo:GO_0032102, obo:GO_0050727, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006954 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006954 ] ) ] . obo:GO_0050729 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the inflammatory response." ; oboInOwl:hasExactSynonym "up regulation of inflammatory response", "up-regulation of inflammatory response", "upregulation of inflammatory response" ; oboInOwl:hasNarrowSynonym "activation of inflammatory response", "stimulation of inflammatory response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050729" ; a owl:Class ; rdfs:label "positive regulation of inflammatory response" ; rdfs:subClassOf obo:GO_0031349, obo:GO_0032103, obo:GO_0050727, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006954 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006954 ] ) ] . obo:GO_0050764 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." ; obo:RO_0002161 obo:NCBITaxon_147537 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050764" ; a owl:Class ; rdfs:label "regulation of phagocytosis" ; rdfs:subClassOf obo:GO_0030100, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0050765 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis." ; oboInOwl:hasExactSynonym "down regulation of phagocytosis", "down-regulation of phagocytosis", "downregulation of phagocytosis" ; oboInOwl:hasNarrowSynonym "inhibition of phagocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050765" ; a owl:Class ; rdfs:label "negative regulation of phagocytosis" ; rdfs:subClassOf obo:GO_0045806, obo:GO_0050764, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0050766 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of phagocytosis." ; oboInOwl:hasExactSynonym "up regulation of phagocytosis", "up-regulation of phagocytosis", "upregulation of phagocytosis" ; oboInOwl:hasNarrowSynonym "activation of phagocytosis", "stimulation of phagocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050766" ; a owl:Class ; rdfs:label "positive regulation of phagocytosis" ; rdfs:subClassOf obo:GO_0045807, obo:GO_0050764, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0050767 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050767" ; a owl:Class ; rdfs:label "regulation of neurogenesis" ; rdfs:subClassOf obo:GO_0051960, obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022008 ] ) ] . obo:GO_0050768 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." ; oboInOwl:hasExactSynonym "down regulation of neurogenesis", "down-regulation of neurogenesis", "downregulation of neurogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of neurogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050768" ; a owl:Class ; rdfs:label "negative regulation of neurogenesis" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0050767, obo:GO_0051961, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022008 ] ) ] . obo:GO_0050769 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." ; oboInOwl:hasExactSynonym "up regulation of neurogenesis", "up-regulation of neurogenesis", "upregulation of neurogenesis" ; oboInOwl:hasNarrowSynonym "activation of neurogenesis", "stimulation of neurogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050769" ; a owl:Class ; rdfs:label "positive regulation of neurogenesis" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0050767, obo:GO_0051962, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022008 ] ) ] . obo:GO_0050770 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050770" ; a owl:Class ; rdfs:label "regulation of axonogenesis" ; rdfs:subClassOf obo:GO_0010975, obo:GO_0022603, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007409 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007409 ] ) ] . obo:GO_0050771 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis." ; oboInOwl:hasExactSynonym "down regulation of axonogenesis", "down-regulation of axonogenesis", "downregulation of axonogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of axonogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050771" ; a owl:Class ; rdfs:label "negative regulation of axonogenesis" ; rdfs:subClassOf obo:GO_0010977, obo:GO_0050768, obo:GO_0050770, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007409 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007409 ] ) ] . obo:GO_0050772 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of axonogenesis." ; oboInOwl:hasExactSynonym "up regulation of axonogenesis", "up-regulation of axonogenesis", "upregulation of axonogenesis" ; oboInOwl:hasNarrowSynonym "activation of axonogenesis", "stimulation of axonogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050772" ; a owl:Class ; rdfs:label "positive regulation of axonogenesis" ; rdfs:subClassOf obo:GO_0031346, obo:GO_0050769, obo:GO_0050770, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007409 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007409 ] ) ] . obo:GO_0050773 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of dendrite development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050773" ; a owl:Class ; rdfs:label "regulation of dendrite development" ; rdfs:subClassOf obo:GO_0010975, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016358 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016358 ] ) ] . obo:GO_0050774 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis." ; oboInOwl:hasExactSynonym "down regulation of dendrite morphogenesis", "down-regulation of dendrite morphogenesis", "downregulation of dendrite morphogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of dendrite morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050774" ; a owl:Class ; rdfs:label "negative regulation of dendrite morphogenesis" ; rdfs:subClassOf obo:GO_0031345, obo:GO_0048814, obo:GO_0050768, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048813 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048813 ] ) ] . obo:GO_0050775 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis." ; oboInOwl:hasExactSynonym "up regulation of dendrite morphogenesis", "up-regulation of dendrite morphogenesis", "upregulation of dendrite morphogenesis" ; oboInOwl:hasNarrowSynonym "activation of dendrite morphogenesis", "stimulation of dendrite morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050775" ; a owl:Class ; rdfs:label "positive regulation of dendrite morphogenesis" ; rdfs:subClassOf obo:GO_0010770, obo:GO_0031346, obo:GO_0048814, obo:GO_0050769, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048813 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048813 ] ) ] . obo:GO_0050776 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050776" ; a owl:Class ; rdfs:label "regulation of immune response" ; rdfs:subClassOf obo:GO_0002682, obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0050777 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ; oboInOwl:hasExactSynonym "down regulation of immune response", "down-regulation of immune response", "downregulation of immune response" ; oboInOwl:hasNarrowSynonym "inhibition of immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050777" ; a owl:Class ; rdfs:label "negative regulation of immune response" ; rdfs:subClassOf obo:GO_0002683, obo:GO_0048585, obo:GO_0050776, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0050778 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ; oboInOwl:hasExactSynonym "up regulation of immune response", "up-regulation of immune response", "upregulation of immune response" ; oboInOwl:hasNarrowSynonym "stimulation of immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050778" ; a owl:Class ; rdfs:label "positive regulation of immune response" ; rdfs:subClassOf obo:GO_0002684, obo:GO_0048584, obo:GO_0050776, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0050789 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ; oboInOwl:hasAlternativeId "GO:0050791" ; oboInOwl:hasExactSynonym "regulation of physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050789" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_candida, go:goslim_pir ; a owl:Class ; rdfs:label "regulation of biological process" ; rdfs:subClassOf obo:GO_0065007, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008150 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008150 ] ) ] . obo:GO_0050790 obo:IAO_0000115 "Any process that modulates the activity of an enzyme." ; oboInOwl:hasAlternativeId "GO:0048552" ; oboInOwl:hasExactSynonym "regulation of enzyme activity" ; oboInOwl:hasNarrowSynonym "regulation of metalloenzyme activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050790" ; oboInOwl:inSubset go:goslim_chembl, go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of catalytic activity" ; rdfs:subClassOf obo:GO_0065009, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003824 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003824 ] ) ] . obo:GO_0050793 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050793" ; a owl:Class ; rdfs:label "regulation of developmental process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032502 ] ) ] . obo:GO_0050794 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; oboInOwl:hasAlternativeId "GO:0051244" ; oboInOwl:hasExactSynonym "regulation of cellular physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050794" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "regulation of cellular process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009987 ] ) ] . obo:GO_0050795 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ; oboInOwl:hasExactSynonym "regulation of behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050795" ; a owl:Class ; rdfs:label "regulation of behavior" ; rdfs:subClassOf obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007610 ] ) ] . obo:GO_0050796 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of insulin." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050796" ; a owl:Class ; rdfs:label "regulation of insulin secretion" ; rdfs:subClassOf obo:GO_0050708, obo:GO_0090276, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030073 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030073 ] ) ] . obo:GO_0050801 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:2000021" ; oboInOwl:hasBroadSynonym "ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "electrolyte homeostasis", "negative regulation of crystal formation", "regulation of ion homeostasis" ; oboInOwl:id "GO:0050801" ; a owl:Class ; rdfs:label "monoatomic ion homeostasis" ; rdfs:subClassOf obo:GO_0048878, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_24867 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_24867 ] ) ] . obo:GO_0050803 obo:IAO_0000115 "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050803" ; a owl:Class ; rdfs:label "regulation of synapse structure or activity" ; rdfs:subClassOf obo:GO_0065008, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_6072 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_6072 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0050804 obo:IAO_0000115 "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." ; oboInOwl:hasBroadSynonym "modulation of synaptic transmission" ; oboInOwl:hasExactSynonym "regulation of chemical synaptic transmission", "regulation of synaptic transmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050804" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "modulation of chemical synaptic transmission" ; rdfs:subClassOf obo:GO_0099177, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0050805 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." ; oboInOwl:hasExactSynonym "down regulation of synaptic transmission", "down-regulation of synaptic transmission", "downregulation of synaptic transmission" ; oboInOwl:hasNarrowSynonym "inhibition of synaptic transmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050805" ; a owl:Class ; rdfs:label "negative regulation of synaptic transmission" ; rdfs:subClassOf obo:GO_0010648, obo:GO_0023057, obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007268 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0050806 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." ; oboInOwl:hasExactSynonym "up regulation of synaptic transmission", "up-regulation of synaptic transmission", "upregulation of synaptic transmission" ; oboInOwl:hasNarrowSynonym "activation of synaptic transmission", "stimulation of synaptic transmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050806" ; a owl:Class ; rdfs:label "positive regulation of synaptic transmission" ; rdfs:subClassOf obo:GO_0010647, obo:GO_0023056, obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007268 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0050807 obo:IAO_0000115 "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ; oboInOwl:hasExactSynonym "regulation of synapse organisation", "regulation of synapse structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of synapse organization and biogenesis" ; oboInOwl:id "GO:0050807" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of synapse organization" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050803 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050808 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050808 ] ) ] . obo:GO_0050808 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ; oboInOwl:hasExactSynonym "synapse organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "synapse development", "synapse morphogenesis", "synapse organization and biogenesis" ; oboInOwl:id "GO:0050808" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_synapse ; a owl:Class ; rdfs:label "synapse organization" ; rdfs:subClassOf obo:GO_0034330, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0050810 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus." ; oboInOwl:hasExactSynonym "regulation of steroid anabolism", "regulation of steroid biosynthesis", "regulation of steroid formation", "regulation of steroid synthesis", "regulation of steroidogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050810" ; a owl:Class ; rdfs:label "regulation of steroid biosynthetic process" ; rdfs:subClassOf obo:GO_0019218, obo:GO_0046890, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006694 ] ) ] . obo:GO_0050821 obo:IAO_0000115 "Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation." ; oboInOwl:hasExactSynonym "positive regulation of protein stability", "protein stabilisation" ; oboInOwl:hasNarrowSynonym "lysosomal protein stabilization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein sequestering", "protein stabilization activity" ; oboInOwl:id "GO:0050821" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "protein stabilization" ; rdfs:subClassOf obo:GO_0031647 . obo:GO_0050832 obo:IAO_0000115 "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism." ; oboInOwl:hasAlternativeId "GO:0009623", "GO:0009817", "GO:0042831" ; oboInOwl:hasExactSynonym "defence response to fungi", "defence response to fungus", "defense response to fungi" ; oboInOwl:hasNarrowSynonym "defense response to fungus, incompatible interaction", "resistance response to pathogenic fungi", "resistance response to pathogenic fungus", "response to parasitic fungi", "response to parasitic fungus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050832" ; a owl:Class ; rdfs:label "defense response to fungus" ; rdfs:subClassOf obo:GO_0006952, obo:GO_0009620 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006952 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:NCBITaxon_4751 ] ) ] . obo:GO_0050839 obo:IAO_0000115 "Binding to a cell adhesion molecule." ; oboInOwl:hasExactSynonym "CAM binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "adhesive extracellular matrix constituent", "cell adhesion molecule activity", "cell adhesion receptor activity" ; oboInOwl:id "GO:0050839" ; a owl:Class ; rdfs:label "cell adhesion molecule binding" ; rdfs:subClassOf obo:GO_0005515 . obo:GO_0050840 obo:IAO_0000115 "Binding to a component of the extracellular matrix." ; oboInOwl:hasExactSynonym "extracellular matrix constituent binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "adhesive extracellular matrix constituent" ; oboInOwl:id "GO:0050840" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "extracellular matrix binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0031012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0031012 ] ) ] . obo:GO_0050848 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response." ; oboInOwl:hasExactSynonym "regulation of calcium-mediated signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050848" ; a owl:Class ; rdfs:label "regulation of calcium-mediated signaling" ; rdfs:subClassOf obo:GO_1902531, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019722 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019722 ] ) ] . obo:GO_0050849 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling." ; oboInOwl:hasExactSynonym "down regulation of calcium-mediated signaling", "down-regulation of calcium-mediated signaling", "downregulation of calcium-mediated signaling", "negative regulation of calcium-mediated signalling" ; oboInOwl:hasNarrowSynonym "inhibition of calcium-mediated signaling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050849" ; a owl:Class ; rdfs:label "negative regulation of calcium-mediated signaling" ; rdfs:subClassOf obo:GO_0050848, obo:GO_1902532, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019722 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019722 ] ) ] . obo:GO_0050850 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling." ; oboInOwl:hasExactSynonym "positive regulation of calcium-mediated signalling", "up regulation of calcium-mediated signaling", "up-regulation of calcium-mediated signaling", "upregulation of calcium-mediated signaling" ; oboInOwl:hasNarrowSynonym "activation of calcium-mediated signaling", "stimulation of calcium-mediated signaling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050850" ; a owl:Class ; rdfs:label "positive regulation of calcium-mediated signaling" ; rdfs:subClassOf obo:GO_0050848, obo:GO_1902533, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019722 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019722 ] ) ] . obo:GO_0050863 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of T cell activation." ; oboInOwl:hasExactSynonym "regulation of T lymphocyte activation", "regulation of T-cell activation", "regulation of T-lymphocyte activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050863" ; a owl:Class ; rdfs:label "regulation of T cell activation" ; rdfs:subClassOf obo:GO_0051249, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042110 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042110 ] ) ] . obo:GO_0050865 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050865" ; a owl:Class ; rdfs:label "regulation of cell activation" ; rdfs:subClassOf obo:GO_0050794, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001775 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001775 ] ) ] . obo:GO_0050866 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation." ; oboInOwl:hasExactSynonym "down regulation of cell activation", "down-regulation of cell activation", "downregulation of cell activation" ; oboInOwl:hasNarrowSynonym "inhibition of cell activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050866" ; a owl:Class ; rdfs:label "negative regulation of cell activation" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0050865, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001775 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001775 ] ) ] . obo:GO_0050867 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of activation." ; oboInOwl:hasExactSynonym "up regulation of cell activation", "up-regulation of cell activation", "upregulation of cell activation" ; oboInOwl:hasNarrowSynonym "activation of cell activation", "stimulation of cell activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050867" ; a owl:Class ; rdfs:label "positive regulation of cell activation" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0050865, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001775 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001775 ] ) ] . obo:GO_0050868 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation." ; oboInOwl:hasExactSynonym "down regulation of T cell activation", "down-regulation of T cell activation", "downregulation of T cell activation", "negative regulation of T lymphocyte activation", "negative regulation of T-cell activation", "negative regulation of T-lymphocyte activation" ; oboInOwl:hasNarrowSynonym "inhibition of T cell activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050868" ; a owl:Class ; rdfs:label "negative regulation of T cell activation" ; rdfs:subClassOf obo:GO_0050863, obo:GO_0051250, obo:GO_1903038, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042110 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042110 ] ) ] . obo:GO_0050870 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of T cell activation." ; oboInOwl:hasExactSynonym "positive regulation of T lymphocyte activation", "positive regulation of T-cell activation", "positive regulation of T-lymphocyte activation", "up regulation of T cell activation", "up-regulation of T cell activation", "upregulation of T cell activation" ; oboInOwl:hasNarrowSynonym "activation of T cell activation", "stimulation of T cell activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050870" ; a owl:Class ; rdfs:label "positive regulation of T cell activation" ; rdfs:subClassOf obo:GO_0050863, obo:GO_0051251, obo:GO_1903039, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042110 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042110 ] ) ] . obo:GO_0050877 obo:IAO_0000115 "A organ system process carried out by any of the organs or tissues of neurological system." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13824"^^xsd:anyURI ; oboInOwl:hasExactSynonym "neurological system process", "neurophysiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pan-neural process" ; oboInOwl:id "GO:0050877" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_pir ; a owl:Class ; rdfs:label "nervous system process" ; rdfs:subClassOf obo:GO_0003008, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:UBERON_0001016 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0003008 [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:UBERON_0001016 ] ) ] . obo:GO_0050878 obo:IAO_0000115 "Any process that modulates the levels of body fluids." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050878" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "regulation of body fluid levels" . obo:GO_0050879 obo:IAO_0000115 "Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050879" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "multicellular organismal movement" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0050881 obo:IAO_0000115 "The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050881" ; a owl:Class ; rdfs:label "musculoskeletal movement" ; rdfs:subClassOf obo:GO_0050879, obo:GO_0050905 . obo:GO_0050886 obo:IAO_0000115 "The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system." ; oboInOwl:hasExactSynonym "endocrine physiological process", "endocrine physiology" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050886" ; oboInOwl:inSubset go:goslim_generic, go:goslim_pir ; a owl:Class ; rdfs:label "endocrine process" ; rdfs:subClassOf obo:GO_0003008 . obo:GO_0050890 obo:IAO_0000115 "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." ; oboInOwl:hasDbXref "Wikipedia:Cognition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050890" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "cognition" ; rdfs:subClassOf obo:GO_0050877 . obo:GO_0050896 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." ; oboInOwl:hasAlternativeId "GO:0051869" ; oboInOwl:hasExactSynonym "physiological response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050896" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to stimulus" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0050900 obo:IAO_0000115 "The movement of a leukocyte within or between different tissues and organs of the body." ; oboInOwl:hasExactSynonym "immune cell migration", "immune cell trafficking", "leucocyte migration", "leucocyte trafficking", "leukocyte trafficking" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050900" ; a owl:Class ; rdfs:label "leukocyte migration" ; rdfs:subClassOf obo:GO_0002376, obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000738 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0050905 obo:IAO_0000115 "Any process pertaining to the functions of the nervous and muscular systems of an organism." ; oboInOwl:hasExactSynonym "neuromotor process", "neuromuscular physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050905" ; a owl:Class ; rdfs:label "neuromuscular process" ; rdfs:subClassOf obo:GO_0050877 . obo:GO_0050906 obo:IAO_0000115 "The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal." ; oboInOwl:hasDbXref "Wikipedia:Transduction_(physiology)" ; oboInOwl:hasExactSynonym "sensory detection of stimulus", "sensory perception, sensory transduction of stimulus", "sensory perception, stimulus detection", "sensory transduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050906" ; a owl:Class ; rdfs:label "detection of stimulus involved in sensory perception" ; rdfs:subClassOf obo:GO_0051606, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007600 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051606 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007600 ] ) ] . obo:GO_0050908 obo:IAO_0000115 "The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal." ; oboInOwl:hasExactSynonym "sensory detection of light during visual perception", "sensory detection of light stimulus during visual perception", "sensory transduction of light during visual perception", "sensory transduction of light stimulus during visual perception", "visual perception, detection of light stimulus", "visual perception, sensory transduction during perception of light", "visual perception, sensory transduction of light stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050908" ; a owl:Class ; rdfs:label "detection of light stimulus involved in visual perception" ; rdfs:subClassOf obo:GO_0009584, obo:GO_0050962, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007601 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009583 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007601 ] ) ] . obo:GO_0050918 obo:IAO_0000115 "The directed movement of a motile cell or organism towards a higher concentration of a chemical." ; oboInOwl:hasExactSynonym "chemoattraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050918" ; a owl:Class ; rdfs:label "positive chemotaxis" ; rdfs:subClassOf obo:GO_0006935 . obo:GO_0050919 obo:IAO_0000115 "The directed movement of a motile cell or organism towards a lower concentration of a chemical." ; oboInOwl:hasExactSynonym "chemoaversion", "chemorepulsion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050919" ; a owl:Class ; rdfs:label "negative chemotaxis" ; rdfs:subClassOf obo:GO_0006935 . obo:GO_0050920 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050920" ; a owl:Class ; rdfs:label "regulation of chemotaxis" ; rdfs:subClassOf obo:GO_0032101, obo:GO_0040012, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006935 ] ) ] . obo:GO_0050921 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ; oboInOwl:hasExactSynonym "up regulation of chemotaxis", "up-regulation of chemotaxis", "upregulation of chemotaxis" ; oboInOwl:hasNarrowSynonym "activation of chemotaxis", "stimulation of chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050921" ; a owl:Class ; rdfs:label "positive regulation of chemotaxis" ; rdfs:subClassOf obo:GO_0032103, obo:GO_0040017, obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006935 ] ) ] . obo:GO_0050922 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ; oboInOwl:hasExactSynonym "down regulation of chemotaxis", "down-regulation of chemotaxis", "downregulation of chemotaxis" ; oboInOwl:hasNarrowSynonym "inhibition of chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050922" ; a owl:Class ; rdfs:label "negative regulation of chemotaxis" ; rdfs:subClassOf obo:GO_0032102, obo:GO_0040013, obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006935 ] ) ] . obo:GO_0050923 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050923" ; a owl:Class ; rdfs:label "regulation of negative chemotaxis" ; rdfs:subClassOf obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050919 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050919 ] ) ] . obo:GO_0050924 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasExactSynonym "up regulation of negative chemotaxis", "up-regulation of negative chemotaxis", "upregulation of negative chemotaxis" ; oboInOwl:hasNarrowSynonym "activation of negative chemotaxis", "stimulation of negative chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050924" ; a owl:Class ; rdfs:label "positive regulation of negative chemotaxis" ; rdfs:subClassOf obo:GO_0050921, obo:GO_0050923, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050919 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050919 ] ) ] . obo:GO_0050925 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasExactSynonym "down regulation of negative chemotaxis", "down-regulation of negative chemotaxis", "downregulation of negative chemotaxis" ; oboInOwl:hasNarrowSynonym "inhibition of negative chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050925" ; a owl:Class ; rdfs:label "negative regulation of negative chemotaxis" ; rdfs:subClassOf obo:GO_0050922, obo:GO_0050923, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050919 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050919 ] ) ] . obo:GO_0050926 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050926" ; a owl:Class ; rdfs:label "regulation of positive chemotaxis" ; rdfs:subClassOf obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050918 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050918 ] ) ] . obo:GO_0050927 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasExactSynonym "up regulation of positive chemotaxis", "up-regulation of positive chemotaxis", "upregulation of positive chemotaxis" ; oboInOwl:hasNarrowSynonym "activation of positive chemotaxis", "stimulation of positive chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050927" ; a owl:Class ; rdfs:label "positive regulation of positive chemotaxis" ; rdfs:subClassOf obo:GO_0050921, obo:GO_0050926, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050918 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050918 ] ) ] . obo:GO_0050928 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasExactSynonym "down regulation of positive chemotaxis", "down-regulation of positive chemotaxis", "downregulation of positive chemotaxis" ; oboInOwl:hasNarrowSynonym "inhibition of positive chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050928" ; a owl:Class ; rdfs:label "negative regulation of positive chemotaxis" ; rdfs:subClassOf obo:GO_0050922, obo:GO_0050926, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050918 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050918 ] ) ] . obo:GO_0050931 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte." ; oboInOwl:hasAlternativeId "GO:0043357", "GO:0043358" ; oboInOwl:hasExactSynonym "chromatophore differentiation", "pigmented cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050931" ; a owl:Class ; rdfs:comment "Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore." ; rdfs:label "pigment cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048066 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000147 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000147 ] ) ] . obo:GO_0050932 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of pigmented cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050932" ; a owl:Class ; rdfs:label "regulation of pigment cell differentiation" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050931 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050931 ] ) ] . obo:GO_0050941 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of pigment cell differentiation", "down-regulation of pigment cell differentiation", "downregulation of pigment cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of pigment cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050941" ; a owl:Class ; rdfs:label "negative regulation of pigment cell differentiation" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0048086, obo:GO_0050932, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050931 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050931 ] ) ] . obo:GO_0050942 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of pigment cell differentiation", "up-regulation of pigment cell differentiation", "upregulation of pigment cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of pigment cell differentiation", "stimulation of pigment cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050942" ; a owl:Class ; rdfs:label "positive regulation of pigment cell differentiation" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0048087, obo:GO_0050932, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050931 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050931 ] ) ] . obo:GO_0050953 obo:IAO_0000115 "The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050953" ; a owl:Class ; rdfs:label "sensory perception of light stimulus" ; rdfs:subClassOf obo:GO_0007600 . obo:GO_0050954 obo:IAO_0000115 "The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process." ; oboInOwl:hasExactSynonym "mechanosensory perception", "perception of mechanical stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chemi-mechanical coupling" ; oboInOwl:id "GO:0050954" ; a owl:Class ; rdfs:label "sensory perception of mechanical stimulus" ; rdfs:subClassOf obo:GO_0007600 . obo:GO_0050962 obo:IAO_0000115 "The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light." ; oboInOwl:hasExactSynonym "sensory detection of light stimulus", "sensory detection of light stimulus during sensory perception", "sensory perception, sensory detection of light stimulus", "sensory perception, sensory transduction of light stimulus", "sensory transduction of light stimulus", "sensory transduction of light stimulus during sensory perception" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050962" ; a owl:Class ; rdfs:label "detection of light stimulus involved in sensory perception" ; rdfs:subClassOf obo:GO_0009583, obo:GO_0050906, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050953 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009583 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007600 ] ) ] . obo:GO_0050975 obo:IAO_0000115 "The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach)." ; oboInOwl:hasDbXref "Wikipedia:Touch" ; oboInOwl:hasExactSynonym "perception of touch", "tactile sense", "taction", "tactition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050975" ; a owl:Class ; rdfs:label "sensory perception of touch" ; rdfs:subClassOf obo:GO_0050954 . obo:GO_0050994 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids." ; oboInOwl:hasExactSynonym "regulation of lipid breakdown", "regulation of lipid catabolism", "regulation of lipid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050994" ; a owl:Class ; rdfs:label "regulation of lipid catabolic process" ; rdfs:subClassOf obo:GO_0009894, obo:GO_0019216, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016042 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016042 ] ) ] . obo:GO_0050995 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." ; oboInOwl:hasExactSynonym "down regulation of lipid catabolic process", "down-regulation of lipid catabolic process", "downregulation of lipid catabolic process", "negative regulation of lipid breakdown", "negative regulation of lipid catabolism", "negative regulation of lipid degradation" ; oboInOwl:hasNarrowSynonym "inhibition of lipid catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050995" ; a owl:Class ; rdfs:label "negative regulation of lipid catabolic process" ; rdfs:subClassOf obo:GO_0009895, obo:GO_0045833, obo:GO_0050994, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016042 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016042 ] ) ] . obo:GO_0050996 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids." ; oboInOwl:hasExactSynonym "positive regulation of lipid breakdown", "positive regulation of lipid catabolism", "positive regulation of lipid degradation", "up regulation of lipid catabolic process", "up-regulation of lipid catabolic process", "upregulation of lipid catabolic process" ; oboInOwl:hasNarrowSynonym "activation of lipid catabolic process", "stimulation of lipid catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050996" ; a owl:Class ; rdfs:label "positive regulation of lipid catabolic process" ; rdfs:subClassOf obo:GO_0009896, obo:GO_0045834, obo:GO_0050994, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016042 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016042 ] ) ] . obo:GO_0051017 obo:IAO_0000115 "The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness." ; oboInOwl:hasAlternativeId "GO:0045011" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "actin bundling activity", "actin cable assembly", "actin cable formation" ; oboInOwl:id "GO:0051017" ; a owl:Class ; rdfs:label "actin filament bundle assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0061572, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0032432 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0032432 ] ) ] . obo:GO_0051027 obo:IAO_0000115 "The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051027" ; a owl:Class ; rdfs:label "DNA transport" ; rdfs:subClassOf obo:GO_0050657, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16991 ] ) ] . obo:GO_0051028 obo:IAO_0000115 "The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051028" ; a owl:Class ; rdfs:label "mRNA transport" ; rdfs:subClassOf obo:GO_0050658 . obo:GO_0051032 obo:IAO_0000115 "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0051032" ; a owl:Class ; rdfs:label "nucleic acid transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015932, obo:GO_0022884, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050657 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33696 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33696 ] ) ] . obo:GO_0051033 obo:IAO_0000115 "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other." ; oboInOwl:hasDbXref "Reactome:R-HSA-203906" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0051033" ; a owl:Class ; rdfs:label "RNA transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0051032, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050658 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33697 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33697 ] ) ] . obo:GO_0051035 obo:IAO_0000115 "Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0051035" ; a owl:Class ; rdfs:label "DNA transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0051032, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022857 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_16991 ] ) ] . obo:GO_0051037 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle." ; oboInOwl:hasExactSynonym "meiotic regulation of transcription", "regulation of transcription, meiotic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051037" ; a owl:Class ; rdfs:label "regulation of transcription involved in meiotic cell cycle" ; rdfs:subClassOf obo:GO_0006355, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006355 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051038 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle." ; oboInOwl:hasExactSynonym "down regulation of transcription during meiosis", "down-regulation of transcription during meiosis", "downregulation of transcription during meiosis", "meiotic repression of transcription", "negative regulation of meiotic transcription", "negative regulation of transcription, meiotic" ; oboInOwl:hasNarrowSynonym "inhibition of transcription during meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051038" ; a owl:Class ; rdfs:label "negative regulation of transcription involved in meiotic cell cycle" ; rdfs:subClassOf obo:GO_0045892, obo:GO_0051037 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045892 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051039 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle." ; oboInOwl:hasExactSynonym "positive regulation of meiotic transcription", "positive regulation of transcription, meiotic", "up regulation of transcription during meiosis", "up-regulation of transcription during meiosis", "upregulation of transcription during meiosis" ; oboInOwl:hasNarrowSynonym "activation of transcription during meiosis", "stimulation of transcription during meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051039" ; a owl:Class ; rdfs:label "positive regulation of transcription involved in meiotic cell cycle" ; rdfs:subClassOf obo:GO_0045893, obo:GO_0051037 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045893 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051046 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051046" ; a owl:Class ; rdfs:label "regulation of secretion" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046903 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046903 ] ) ] . obo:GO_0051047 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ; oboInOwl:hasExactSynonym "up regulation of secretion", "up-regulation of secretion", "upregulation of secretion" ; oboInOwl:hasNarrowSynonym "activation of secretion", "stimulation of secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051047" ; a owl:Class ; rdfs:label "positive regulation of secretion" ; rdfs:subClassOf obo:GO_0051046, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046903 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046903 ] ) ] . obo:GO_0051048 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ; oboInOwl:hasExactSynonym "down regulation of secretion", "down-regulation of secretion", "downregulation of secretion" ; oboInOwl:hasNarrowSynonym "inhibition of secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051048" ; a owl:Class ; rdfs:label "negative regulation of secretion" ; rdfs:subClassOf obo:GO_0051046, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046903 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046903 ] ) ] . obo:GO_0051049 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051049" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of transport" ; rdfs:subClassOf obo:GO_0032879, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006810 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006810 ] ) ] . obo:GO_0051050 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of transport", "up-regulation of transport", "upregulation of transport" ; oboInOwl:hasNarrowSynonym "activation of transport", "stimulation of transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051050" ; a owl:Class ; rdfs:label "positive regulation of transport" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006810 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006810 ] ) ] . obo:GO_0051051 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of transport", "down-regulation of transport", "downregulation of transport" ; oboInOwl:hasNarrowSynonym "inhibition of transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051051" ; a owl:Class ; rdfs:label "negative regulation of transport" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006810 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006810 ] ) ] . obo:GO_0051052 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." ; oboInOwl:hasExactSynonym "regulation of DNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051052" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of DNA metabolic process" ; rdfs:subClassOf obo:GO_0019219, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006259 ] ) ] . obo:GO_0051053 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." ; oboInOwl:hasExactSynonym "down regulation of DNA metabolic process", "down-regulation of DNA metabolic process", "downregulation of DNA metabolic process", "negative regulation of DNA metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of DNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051053" ; a owl:Class ; rdfs:label "negative regulation of DNA metabolic process" ; rdfs:subClassOf obo:GO_0010605, obo:GO_0045934, obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006259 ] ) ] . obo:GO_0051054 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." ; oboInOwl:hasExactSynonym "positive regulation of DNA metabolism", "up regulation of DNA metabolic process", "up-regulation of DNA metabolic process", "upregulation of DNA metabolic process" ; oboInOwl:hasNarrowSynonym "activation of DNA metabolic process", "stimulation of DNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051054" ; a owl:Class ; rdfs:label "positive regulation of DNA metabolic process" ; rdfs:subClassOf obo:GO_0010604, obo:GO_0045935, obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006259 ] ) ] . obo:GO_0051055 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ; oboInOwl:hasExactSynonym "down regulation of lipid biosynthetic process", "down-regulation of lipid biosynthetic process", "downregulation of lipid biosynthetic process", "negative regulation of lipid anabolism", "negative regulation of lipid biosynthesis", "negative regulation of lipid formation", "negative regulation of lipid synthesis", "negative regulation of lipogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of lipid biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051055" ; a owl:Class ; rdfs:label "negative regulation of lipid biosynthetic process" ; rdfs:subClassOf obo:GO_0009890, obo:GO_0045833, obo:GO_0046890, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008610 ] ) ] . obo:GO_0051078 obo:IAO_0000115 "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiotic nuclear envelope breakdown", "meiotic nuclear envelope catabolism", "meiotic nuclear envelope degradation", "meiotic nuclear envelope disassembly" ; oboInOwl:id "GO:0051078" ; a owl:Class ; rdfs:label "meiotic nuclear membrane disassembly" ; rdfs:subClassOf obo:GO_0051081, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051081 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051079 obo:IAO_0000115 "The controlled breakdown of the nuclear membranes during the first division of meiosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiosis I nuclear envelope breakdown", "meiosis I nuclear envelope catabolism", "meiosis I nuclear envelope degradation", "meiosis I nuclear envelope disassembly" ; oboInOwl:id "GO:0051079" ; a owl:Class ; rdfs:label "meiosis I nuclear membrane disassembly" ; rdfs:subClassOf obo:GO_0051078, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051081 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0051080 obo:IAO_0000115 "The controlled breakdown of the nuclear membranes during the second division of meiosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiosis II nuclear envelope breakdown", "meiosis II nuclear envelope catabolism", "meiosis II nuclear envelope degradation", "meiosis II nuclear envelope disassembly" ; oboInOwl:id "GO:0051080" ; a owl:Class ; rdfs:label "meiosis II nuclear membrane disassembly" ; rdfs:subClassOf obo:GO_0051078, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007135 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051081 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007135 ] ) ] . obo:GO_0051081 obo:IAO_0000115 "The controlled breakdown of the nuclear membranes, for example during cellular division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear envelope breakdown", "nuclear envelope catabolism", "nuclear envelope degradation", "nuclear envelope disassembly" ; oboInOwl:id "GO:0051081" ; a owl:Class ; rdfs:label "nuclear membrane disassembly" ; rdfs:subClassOf obo:GO_0030397, obo:GO_0071763, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0031965 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0031965 ] ) ] . obo:GO_0051093 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ; oboInOwl:hasExactSynonym "down regulation of developmental process", "down-regulation of developmental process", "downregulation of developmental process" ; oboInOwl:hasNarrowSynonym "inhibition of developmental process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051093" ; a owl:Class ; rdfs:label "negative regulation of developmental process" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032502 ] ) ] . obo:GO_0051094 obo:IAO_0000115 "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ; oboInOwl:hasExactSynonym "up regulation of developmental process", "up-regulation of developmental process", "upregulation of developmental process" ; oboInOwl:hasNarrowSynonym "activation of developmental process", "stimulation of developmental process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051094" ; a owl:Class ; rdfs:label "positive regulation of developmental process" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032502 ] ) ] . obo:GO_0051098 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051098" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of binding" ; rdfs:subClassOf obo:GO_0065009, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005488 ] ) ] . obo:GO_0051099 obo:IAO_0000115 "Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ; oboInOwl:hasExactSynonym "up regulation of binding", "up-regulation of binding", "upregulation of binding" ; oboInOwl:hasNarrowSynonym "activation of binding", "stimulation of binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051099" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of binding" ; rdfs:subClassOf obo:GO_0044093, obo:GO_0051098, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005488 ] ) ] . obo:GO_0051100 obo:IAO_0000115 "Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ; oboInOwl:hasExactSynonym "down regulation of binding", "down-regulation of binding", "downregulation of binding" ; oboInOwl:hasNarrowSynonym "inhibition of binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051100" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of binding" ; rdfs:subClassOf obo:GO_0044092, obo:GO_0051098, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005488 ] ) ] . obo:GO_0051101 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051101" ; a owl:Class ; rdfs:label "regulation of DNA binding" ; rdfs:subClassOf obo:GO_0051098, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003677 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003677 ] ) ] . obo:GO_0051119 obo:IAO_0000115 "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides." ; oboInOwl:hasDbXref "Reactome:R-HSA-428779", "Reactome:R-HSA-8875902", "Reactome:R-HSA-8876319" ; oboInOwl:hasNarrowSynonym "sugar/polyol channel activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0051119" ; a owl:Class ; rdfs:label "sugar transmembrane transporter activity" ; rdfs:subClassOf obo:GO_0015144 . obo:GO_0051128 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; oboInOwl:hasExactSynonym "regulation of cellular component organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cell organisation", "regulation of cell organization", "regulation of cellular component organization and biogenesis" ; oboInOwl:id "GO:0051128" ; a owl:Class ; rdfs:label "regulation of cellular component organization" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016043 ] ) ] . obo:GO_0051129 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; oboInOwl:hasExactSynonym "down regulation of cell organization", "down-regulation of cell organization", "downregulation of cell organization" ; oboInOwl:hasNarrowSynonym "inhibition of cell organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell organisation", "negative regulation of cellular component organization and biogenesis" ; oboInOwl:id "GO:0051129" ; a owl:Class ; rdfs:label "negative regulation of cellular component organization" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016043 ] ) ] . obo:GO_0051130 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; oboInOwl:hasExactSynonym "positive regulation of cell organisation", "up regulation of cell organization", "up-regulation of cell organization", "upregulation of cell organization" ; oboInOwl:hasNarrowSynonym "activation of cell organization", "stimulation of cell organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cellular component organization and biogenesis" ; oboInOwl:id "GO:0051130" ; a owl:Class ; rdfs:label "positive regulation of cellular component organization" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016043 ] ) ] . obo:GO_0051145 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary." ; oboInOwl:hasExactSynonym "nonstriated muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051145" ; a owl:Class ; rdfs:label "smooth muscle cell differentiation" ; rdfs:subClassOf obo:GO_0042692, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000192 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000192 ] ) ] . obo:GO_0051146 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle." ; oboInOwl:hasNarrowSynonym "voluntary muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051146" ; a owl:Class ; rdfs:label "striated muscle cell differentiation" ; rdfs:subClassOf obo:GO_0042692, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000737 ] ) ] . obo:GO_0051147 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of muscle cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051147" ; a owl:Class ; rdfs:label "regulation of muscle cell differentiation" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042692 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042692 ] ) ] . obo:GO_0051148 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of muscle cell differentiation", "down-regulation of muscle cell differentiation", "downregulation of muscle cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051148" ; a owl:Class ; rdfs:label "negative regulation of muscle cell differentiation" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0051147, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042692 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042692 ] ) ] . obo:GO_0051149 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of muscle cell differentiation", "up-regulation of muscle cell differentiation", "upregulation of muscle cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of muscle cell differentiation", "stimulation of muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051149" ; a owl:Class ; rdfs:label "positive regulation of muscle cell differentiation" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0051147, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042692 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042692 ] ) ] . obo:GO_0051150 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051150" ; a owl:Class ; rdfs:label "regulation of smooth muscle cell differentiation" ; rdfs:subClassOf obo:GO_0051147, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051145 ] ) ] . obo:GO_0051151 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of smooth muscle cell differentiation", "down-regulation of smooth muscle cell differentiation", "downregulation of smooth muscle cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of smooth muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051151" ; a owl:Class ; rdfs:label "negative regulation of smooth muscle cell differentiation" ; rdfs:subClassOf obo:GO_0051148, obo:GO_0051150, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051145 ] ) ] . obo:GO_0051152 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of smooth muscle cell differentiation", "up-regulation of smooth muscle cell differentiation", "upregulation of smooth muscle cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of smooth muscle cell differentiation", "stimulation of smooth muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051152" ; a owl:Class ; rdfs:label "positive regulation of smooth muscle cell differentiation" ; rdfs:subClassOf obo:GO_0051149, obo:GO_0051150, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051145 ] ) ] . obo:GO_0051153 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051153" ; a owl:Class ; rdfs:label "regulation of striated muscle cell differentiation" ; rdfs:subClassOf obo:GO_0051147, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051146 ] ) ] . obo:GO_0051154 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of striated muscle cell differentiation", "down-regulation of striated muscle cell differentiation", "downregulation of striated muscle cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of striated muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051154" ; a owl:Class ; rdfs:label "negative regulation of striated muscle cell differentiation" ; rdfs:subClassOf obo:GO_0051148, obo:GO_0051153, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051146 ] ) ] . obo:GO_0051155 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of striated muscle cell differentiation", "up-regulation of striated muscle cell differentiation", "upregulation of striated muscle cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of striated muscle cell differentiation", "stimulation of striated muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051155" ; a owl:Class ; rdfs:label "positive regulation of striated muscle cell differentiation" ; rdfs:subClassOf obo:GO_0051149, obo:GO_0051153, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051146 ] ) ] . obo:GO_0051168 obo:IAO_0000115 "The directed movement of substances out of the nucleus." ; oboInOwl:hasExactSynonym "export from nucleus", "nucleus export", "substance nuclear export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051168" ; a owl:Class ; rdfs:label "nuclear export" ; rdfs:subClassOf obo:GO_0006913 . obo:GO_0051169 obo:IAO_0000115 "The directed movement of substances into, out of, or within the nucleus." ; oboInOwl:hasDbXref "Wikipedia:Nuclear_transport" ; oboInOwl:hasExactSynonym "nucleus transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051169" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "nuclear transport" ; rdfs:subClassOf obo:GO_0046907, [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0051170 obo:IAO_0000115 "The directed movement of substances into the nucleus." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-19T15:26:34Z" ; oboInOwl:hasAlternativeId "GO:1902593" ; oboInOwl:hasExactSynonym "nuclear import", "nuclear translocation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051170" ; a owl:Class ; rdfs:label "import into nucleus" ; rdfs:subClassOf obo:GO_0006913 . obo:GO_0051171 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." ; oboInOwl:hasExactSynonym "regulation of nitrogen metabolic process", "regulation of nitrogen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051171" ; a owl:Class ; rdfs:label "regulation of nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006807 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006807 ] ) ] . obo:GO_0051172 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." ; oboInOwl:hasExactSynonym "down regulation of nitrogen metabolic process", "down-regulation of nitrogen metabolic process", "downregulation of nitrogen metabolic process", "negative regulation of nitrogen metabolic process", "negative regulation of nitrogen metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of nitrogen metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051172" ; a owl:Class ; rdfs:label "negative regulation of nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0051171, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006807 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006807 ] ) ] . obo:GO_0051173 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." ; oboInOwl:hasExactSynonym "positive regulation of nitrogen metabolic process", "positive regulation of nitrogen metabolism", "up regulation of nitrogen metabolic process", "up-regulation of nitrogen metabolic process", "upregulation of nitrogen metabolic process" ; oboInOwl:hasNarrowSynonym "activation of nitrogen metabolic process", "stimulation of nitrogen metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051173" ; a owl:Class ; rdfs:label "positive regulation of nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0051171, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006807 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006807 ] ) ] . obo:GO_0051174 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ; oboInOwl:hasExactSynonym "regulation of phosphorus metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051174" ; a owl:Class ; rdfs:label "regulation of phosphorus metabolic process" ; rdfs:subClassOf obo:GO_0031323, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006793 ] ) ] . obo:GO_0051175 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." ; oboInOwl:hasExactSynonym "down regulation of sulfur metabolic process", "down-regulation of sulfur metabolic process", "downregulation of sulfur metabolic process", "negative regulation of sulfur metabolism", "negative regulation of sulphur metabolic process", "negative regulation of sulphur metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of sulfur metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051175" ; a owl:Class ; rdfs:label "negative regulation of sulfur metabolic process" ; rdfs:subClassOf obo:GO_0031324, obo:GO_0042762, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006790 ] ) ] . obo:GO_0051176 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur." ; oboInOwl:hasExactSynonym "positive regulation of sulfur metabolism", "positive regulation of sulphur metabolic process", "positive regulation of sulphur metabolism", "up regulation of sulfur metabolic process", "up-regulation of sulfur metabolic process", "upregulation of sulfur metabolic process" ; oboInOwl:hasNarrowSynonym "activation of sulfur metabolic process", "stimulation of sulfur metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051176" ; a owl:Class ; rdfs:label "positive regulation of sulfur metabolic process" ; rdfs:subClassOf obo:GO_0031325, obo:GO_0042762, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006790 ] ) ] . obo:GO_0051179 obo:IAO_0000115 "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-18T13:51:04Z" ; oboInOwl:hasAlternativeId "GO:1902578" ; oboInOwl:hasExactSynonym "establishment and maintenance of localization", "establishment and maintenance of position", "localisation" ; oboInOwl:hasNarrowSynonym "establishment and maintenance of cellular component location", "establishment and maintenance of substance location", "establishment and maintenance of substrate location" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism localization", "single-organism localization" ; oboInOwl:id "GO:0051179" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "localization" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0051216 obo:IAO_0000115 "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ; oboInOwl:hasDbXref "Wikipedia:Chondrogenesis" ; oboInOwl:hasExactSynonym "cartilage biogenesis", "cartilage biosynthesis", "cartilage element development", "cartilage formation", "cartilage organ development", "chondrogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051216" ; a owl:Class ; rdfs:label "cartilage development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001501 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061448 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0007844 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0007844 ] ) ] . obo:GO_0051222 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of protein transport", "up-regulation of protein transport", "upregulation of protein transport" ; oboInOwl:hasNarrowSynonym "activation of protein transport", "stimulation of protein transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051222" ; a owl:Class ; rdfs:label "positive regulation of protein transport" ; rdfs:subClassOf obo:GO_0051050, obo:GO_0051223, obo:GO_1904951, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015031 ] ) ] . obo:GO_0051223 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051223" ; a owl:Class ; rdfs:label "regulation of protein transport" ; rdfs:subClassOf obo:GO_0051049, obo:GO_0070201, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015031 ] ) ] . obo:GO_0051224 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of protein transport", "down-regulation of protein transport", "downregulation of protein transport" ; oboInOwl:hasNarrowSynonym "inhibition of protein transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051224" ; a owl:Class ; rdfs:label "negative regulation of protein transport" ; rdfs:subClassOf obo:GO_0051051, obo:GO_0051223, obo:GO_1904950, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015031 ] ) ] . obo:GO_0051225 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24375"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0051226", "GO:0051227" ; oboInOwl:hasExactSynonym "bipolar spindle biosynthesis", "bipolar spindle formation", "spindle biosynthesis", "spindle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051225" ; a owl:Class ; rdfs:label "spindle assembly" ; rdfs:subClassOf obo:GO_0007051, obo:GO_0140694, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007059 ] . obo:GO_0051231 obo:IAO_0000115 "The cell cycle process in which the distance is lengthened between poles of the spindle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051231" ; a owl:Class ; rdfs:label "spindle elongation" ; rdfs:subClassOf obo:GO_0007017, obo:GO_0022402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007051 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098813 ] . obo:GO_0051232 obo:IAO_0000115 "The lengthening of the distance between poles of the spindle during a meiotic cell cycle." ; oboInOwl:hasExactSynonym "spindle elongation during meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051232" ; a owl:Class ; rdfs:label "meiotic spindle elongation" ; rdfs:subClassOf obo:GO_0051231, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000212 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045132 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051231 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051234 obo:IAO_0000115 "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." ; oboInOwl:hasExactSynonym "establishment of localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051234" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir ; a owl:Class ; rdfs:label "establishment of localization" ; rdfs:subClassOf obo:GO_0051179 . obo:GO_0051235 obo:IAO_0000115 "Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere." ; oboInOwl:hasExactSynonym "maintenance of localization" ; oboInOwl:hasNarrowSynonym "retention", "sequestering", "storage" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051235" ; a owl:Class ; rdfs:label "maintenance of location" ; rdfs:subClassOf obo:GO_0051179 . obo:GO_0051236 obo:IAO_0000115 "The directed movement of RNA to a specific location." ; oboInOwl:hasExactSynonym "RNA positioning", "RNA recruitment", "establishment of RNA localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051236" ; a owl:Class ; rdfs:label "establishment of RNA localization" ; rdfs:subClassOf obo:GO_0051234, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006403 ] . obo:GO_0051239 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051239" ; a owl:Class ; rdfs:label "regulation of multicellular organismal process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032501 ] ) ] . obo:GO_0051240 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ; oboInOwl:hasExactSynonym "up regulation of multicellular organismal process", "up-regulation of multicellular organismal process", "upregulation of multicellular organismal process" ; oboInOwl:hasNarrowSynonym "activation of multicellular organismal process", "stimulation of multicellular organismal process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051240" ; a owl:Class ; rdfs:label "positive regulation of multicellular organismal process" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032501 ] ) ] . obo:GO_0051241 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ; oboInOwl:hasExactSynonym "down regulation of multicellular organismal process", "down-regulation of multicellular organismal process", "downregulation of multicellular organismal process" ; oboInOwl:hasNarrowSynonym "inhibition of multicellular organismal process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051241" ; a owl:Class ; rdfs:label "negative regulation of multicellular organismal process" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032501 ] ) ] . obo:GO_0051246 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0032268" ; oboInOwl:hasExactSynonym "regulation of protein metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cellular protein metabolic process", "regulation of cellular protein metabolism" ; oboInOwl:id "GO:0051246" ; a owl:Class ; rdfs:label "regulation of protein metabolic process" ; rdfs:subClassOf obo:GO_0051171, obo:GO_0060255, obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019538 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019538 ] ) ] . obo:GO_0051247 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0032270" ; oboInOwl:hasExactSynonym "positive regulation of cellular protein metabolic process", "positive regulation of cellular protein metabolism", "positive regulation of protein metabolism", "up regulation of cellular protein metabolic process", "up regulation of protein metabolic process", "up-regulation of cellular protein metabolic process", "up-regulation of protein metabolic process", "upregulation of cellular protein metabolic process", "upregulation of protein metabolic process" ; oboInOwl:hasNarrowSynonym "activation of cellular protein metabolic process", "activation of protein metabolic process", "stimulation of cellular protein metabolic process", "stimulation of protein metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051247" ; a owl:Class ; rdfs:label "positive regulation of protein metabolic process" ; rdfs:subClassOf obo:GO_0010604, obo:GO_0051173, obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019538 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019538 ] ) ] . obo:GO_0051248 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0032269" ; oboInOwl:hasExactSynonym "down regulation of cellular protein metabolic process", "down regulation of protein metabolic process", "down-regulation of cellular protein metabolic process", "down-regulation of protein metabolic process", "downregulation of cellular protein metabolic process", "downregulation of protein metabolic process", "negative regulation of cellular protein metabolic process", "negative regulation of cellular protein metabolism", "negative regulation of protein metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of cellular protein metabolic process", "inhibition of protein metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051248" ; a owl:Class ; rdfs:label "negative regulation of protein metabolic process" ; rdfs:subClassOf obo:GO_0010605, obo:GO_0051172, obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019538 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019538 ] ) ] . obo:GO_0051249 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of lymphocyte activation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051249" ; a owl:Class ; rdfs:label "regulation of lymphocyte activation" ; rdfs:subClassOf obo:GO_0002694, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046649 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046649 ] ) ] . obo:GO_0051250 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation." ; oboInOwl:hasExactSynonym "down regulation of lymphocyte activation", "down-regulation of lymphocyte activation", "downregulation of lymphocyte activation" ; oboInOwl:hasNarrowSynonym "inhibition of lymphocyte activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051250" ; a owl:Class ; rdfs:label "negative regulation of lymphocyte activation" ; rdfs:subClassOf obo:GO_0002695, obo:GO_0051249, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046649 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046649 ] ) ] . obo:GO_0051251 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of lymphocyte activation." ; oboInOwl:hasExactSynonym "up regulation of lymphocyte activation", "up-regulation of lymphocyte activation", "upregulation of lymphocyte activation" ; oboInOwl:hasNarrowSynonym "activation of lymphocyte activation", "stimulation of lymphocyte activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051251" ; a owl:Class ; rdfs:label "positive regulation of lymphocyte activation" ; rdfs:subClassOf obo:GO_0002696, obo:GO_0051249, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046649 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046649 ] ) ] . obo:GO_0051252 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." ; oboInOwl:hasExactSynonym "regulation of RNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051252" ; a owl:Class ; rdfs:label "regulation of RNA metabolic process" ; rdfs:subClassOf obo:GO_0019219, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016070 ] ) ] . obo:GO_0051253 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." ; oboInOwl:hasExactSynonym "down regulation of RNA metabolic process", "down-regulation of RNA metabolic process", "downregulation of RNA metabolic process", "negative regulation of RNA metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of RNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051253" ; a owl:Class ; rdfs:label "negative regulation of RNA metabolic process" ; rdfs:subClassOf obo:GO_0010605, obo:GO_0045934, obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016070 ] ) ] . obo:GO_0051254 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." ; oboInOwl:hasExactSynonym "positive regulation of RNA metabolism", "up regulation of RNA metabolic process", "up-regulation of RNA metabolic process", "upregulation of RNA metabolic process" ; oboInOwl:hasNarrowSynonym "activation of RNA metabolic process", "stimulation of RNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051254" ; a owl:Class ; rdfs:label "positive regulation of RNA metabolic process" ; rdfs:subClassOf obo:GO_0010604, obo:GO_0045935, obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016070 ] ) ] . obo:GO_0051258 obo:IAO_0000115 "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." ; oboInOwl:hasExactSynonym "protein polymer biosynthesis", "protein polymer biosynthetic process", "protein polymer formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051258" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "protein polymerization" ; rdfs:subClassOf obo:GO_0065003 . obo:GO_0051259 obo:IAO_0000115 "The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-05T09:57:49Z" ; oboInOwl:hasAlternativeId "GO:0035786" ; oboInOwl:hasBroadSynonym "protein oligomer biosynthesis", "protein oligomer biosynthetic process" ; oboInOwl:hasExactSynonym "protein oligomer assembly", "protein oligomer formation", "protein oligomerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein multimerization" ; oboInOwl:id "GO:0051259" ; a owl:Class ; rdfs:label "protein complex oligomerization" ; rdfs:subClassOf obo:GO_0065003 . obo:GO_0051261 obo:IAO_0000115 "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." ; oboInOwl:hasExactSynonym "protein polymer breakdown", "protein polymer catabolic process", "protein polymer catabolism", "protein polymer degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051261" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "protein depolymerization" ; rdfs:subClassOf obo:GO_0032984 . obo:GO_0051276 obo:IAO_0000115 "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22811"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/4585"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006323", "GO:0007001", "GO:0051277" ; oboInOwl:hasExactSynonym "DNA condensation", "chromosome organisation" ; oboInOwl:hasNarrowSynonym "DNA packaging" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosome organization and biogenesis", "maintenance of genome integrity", "nuclear genome maintenance" ; oboInOwl:id "GO:0051276" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:label "chromosome organization" ; rdfs:subClassOf obo:GO_0006996, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005694 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005694 ] ) ] . obo:GO_0051293 obo:IAO_0000115 "The directed movement of the spindle to a specific location in the cell." ; oboInOwl:hasExactSynonym "establishment of spindle localisation", "spindle positioning" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051293" ; a owl:Class ; rdfs:label "establishment of spindle localization" ; rdfs:subClassOf obo:GO_0000226, obo:GO_0051649, obo:GO_0051653, obo:GO_0051656 . obo:GO_0051294 obo:IAO_0000115 "Any process that set the alignment of spindle relative to other cellular structures." ; oboInOwl:hasExactSynonym "orienting of spindle", "spindle orientation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051294" ; a owl:Class ; rdfs:label "establishment of spindle orientation" ; rdfs:subClassOf obo:GO_0051293, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030010 ] . obo:GO_0051295 obo:IAO_0000115 "The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs." ; oboInOwl:hasExactSynonym "establishment of meiotic spindle localisation", "meiotic spindle positioning", "spindle positioning involved in meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "spindle positioning during meiosis" ; oboInOwl:id "GO:0051295" ; a owl:Class ; rdfs:label "establishment of meiotic spindle localization" ; rdfs:subClassOf obo:GO_0051293, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051293 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051296 obo:IAO_0000115 "Any process that set the alignment of meiotic spindle relative to other cellular structures." ; oboInOwl:hasExactSynonym "establishment of spindle orientation involved in meiotic cell cycle", "meiotic spindle orientation", "orienting of meiotic spindle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "establishment of spindle orientation during meiosis" ; oboInOwl:id "GO:0051296" ; a owl:Class ; rdfs:label "establishment of meiotic spindle orientation" ; rdfs:subClassOf obo:GO_0051294, obo:GO_0051295 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051294 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051301 obo:IAO_0000115 "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." ; oboInOwl:hasDbXref "Wikipedia:Cell_division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051301" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:comment "Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division." ; rdfs:label "cell division" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0051302 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051302" ; a owl:Class ; rdfs:label "regulation of cell division" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051301 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051301 ] ) ] . obo:GO_0051303 obo:IAO_0000115 "The directed movement of a chromosome to a specific location." ; oboInOwl:hasExactSynonym "chromosome positioning", "establishment of chromosome localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051303" ; a owl:Class ; rdfs:label "establishment of chromosome localization" ; rdfs:subClassOf obo:GO_0050000, obo:GO_0051649, obo:GO_0051656 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051234 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005694 ] ) ] . obo:GO_0051304 obo:IAO_0000115 "The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II)." ; oboInOwl:hasAlternativeId "GO:0034500" ; oboInOwl:hasNarrowSynonym "rDNA separation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromatid release" ; oboInOwl:id "GO:0051304" ; a owl:Class ; rdfs:label "chromosome separation" ; rdfs:subClassOf obo:GO_0022402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007059 ] . obo:GO_0051306 obo:IAO_0000115 "The process in which sister chromatids are physically detached from each other during mitosis." ; oboInOwl:hasExactSynonym "mitotic sister chromatid resolution", "sister chromatid separation during mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosome separation during mitosis", "mitotic chromosome separation" ; oboInOwl:id "GO:0051306" ; a owl:Class ; rdfs:label "mitotic sister chromatid separation" ; rdfs:subClassOf obo:GO_0051304, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ] . obo:GO_0051307 obo:IAO_0000115 "The process in which chromosomes are physically detached from each other during meiosis." ; oboInOwl:hasExactSynonym "chromosome separation during meiosis", "meiotic chromosome resolution" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051307" ; a owl:Class ; rdfs:label "meiotic chromosome separation" ; rdfs:subClassOf obo:GO_0051304, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045132 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051304 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051308 obo:IAO_0000115 "The process in which paired chromosomes are physically detached from each other during male meiosis." ; oboInOwl:hasExactSynonym "chromosome separation during male meiosis", "male meiosis chromosome resolution" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051308" ; a owl:Class ; rdfs:label "male meiosis chromosome separation" ; rdfs:subClassOf obo:GO_0007060, obo:GO_0051307 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051304 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ) ] . obo:GO_0051309 obo:IAO_0000115 "The process in which paired chromosomes are physically detached from each other during female meiosis." ; oboInOwl:hasExactSynonym "chromosome separation during female meiosis", "female meiosis chromosome resolution" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051309" ; a owl:Class ; rdfs:label "female meiosis chromosome separation" ; rdfs:subClassOf obo:GO_0016321, obo:GO_0051307 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051304 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ) ] . obo:GO_0051310 obo:IAO_0000115 "The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle." ; oboInOwl:hasExactSynonym "chromosome congression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051310" ; a owl:Class ; rdfs:label "metaphase plate congression" ; rdfs:subClassOf obo:GO_0051303, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098813 ] . obo:GO_0051311 obo:IAO_0000115 "The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis." ; oboInOwl:hasExactSynonym "metaphase plate congression during meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051311" ; a owl:Class ; rdfs:label "meiotic metaphase plate congression" ; rdfs:subClassOf obo:GO_0051310, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045132 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051310 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051318 obo:IAO_0000115 "The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis." ; oboInOwl:hasDbXref "Wikipedia:G1_phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051318" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "G1 phase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051325 ] . obo:GO_0051320 obo:IAO_0000115 "The cell cycle phase, following G1, during which DNA synthesis takes place." ; oboInOwl:hasDbXref "Wikipedia:S_phase" ; oboInOwl:hasExactSynonym "S-phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051320" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "S phase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051325 ] . obo:GO_0051321 obo:IAO_0000115 "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24599"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0007126" ; oboInOwl:hasDbXref "Wikipedia:Meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiosis" ; oboInOwl:id "GO:0051321" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle." ; rdfs:label "meiotic cell cycle" ; rdfs:subClassOf obo:GO_0007049, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019953 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0140013 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007049 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0051325 obo:IAO_0000115 "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs." ; oboInOwl:hasBroadSynonym "resting phase" ; oboInOwl:hasDbXref "Wikipedia:Interphase" ; oboInOwl:hasExactSynonym "karyostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051325" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "interphase" ; rdfs:subClassOf obo:GO_0022403 . obo:GO_0051326 obo:IAO_0000115 "The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." ; oboInOwl:hasDbXref "Wikipedia:Telophase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051326" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "telophase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000279 ] . obo:GO_0051327 obo:IAO_0000115 "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle." ; oboInOwl:hasExactSynonym "M phase of meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051327" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiotic M phase" ; rdfs:subClassOf obo:GO_0000279, obo:GO_0098762 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000279 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051328 obo:IAO_0000115 "The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA." ; oboInOwl:hasExactSynonym "interphase of meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051328" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiotic interphase" ; rdfs:subClassOf obo:GO_0051325, obo:GO_0098762 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051325 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051329 obo:IAO_0000115 "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs." ; oboInOwl:hasExactSynonym "interphase of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051329" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "mitotic interphase" ; rdfs:subClassOf obo:GO_0051325, obo:GO_0098763 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051325 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0051333 obo:IAO_0000115 "The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20636"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiotic nuclear envelope reassembly" ; oboInOwl:id "GO:0051333" ; a owl:Class ; rdfs:label "meiotic nuclear membrane reassembly" ; rdfs:subClassOf obo:GO_0031468, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031468 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051334 obo:IAO_0000115 "The reformation of the nuclear membranes during meiosis I." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20636"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiosis I nuclear envelope reassembly" ; oboInOwl:id "GO:0051334" ; a owl:Class ; rdfs:label "meiosis I nuclear membrane reassembly" ; rdfs:subClassOf obo:GO_0051333, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031468 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0051336 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." ; oboInOwl:hasExactSynonym "hydrolase regulator" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051336" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of hydrolase activity" ; rdfs:subClassOf obo:GO_0050790, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016787 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016787 ] ) ] . obo:GO_0051338 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." ; oboInOwl:hasExactSynonym "transferase regulator" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051338" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead." ; rdfs:label "regulation of transferase activity" ; rdfs:subClassOf obo:GO_0050790, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016740 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016740 ] ) ] . obo:GO_0051345 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." ; oboInOwl:hasExactSynonym "hydrolase activator", "up regulation of hydrolase activity", "up-regulation of hydrolase activity", "upregulation of hydrolase activity" ; oboInOwl:hasNarrowSynonym "activation of hydrolase activity", "stimulation of hydrolase activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051345" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of hydrolase activity" ; rdfs:subClassOf obo:GO_0043085, obo:GO_0051336, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016787 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016787 ] ) ] . obo:GO_0051346 obo:IAO_0000115 "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds." ; oboInOwl:hasExactSynonym "down regulation of hydrolase activity", "down-regulation of hydrolase activity", "downregulation of hydrolase activity", "hydrolase inhibitor" ; oboInOwl:hasNarrowSynonym "inhibition of hydrolase activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051346" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of hydrolase activity" ; rdfs:subClassOf obo:GO_0043086, obo:GO_0051336, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016787 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016787 ] ) ] . obo:GO_0051347 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." ; oboInOwl:hasExactSynonym "transferase activator", "up regulation of transferase activity", "up-regulation of transferase activity", "upregulation of transferase activity" ; oboInOwl:hasNarrowSynonym "activation of transferase activity", "stimulation of transferase activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051347" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead." ; rdfs:label "positive regulation of transferase activity" ; rdfs:subClassOf obo:GO_0043085, obo:GO_0051338, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016740 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016740 ] ) ] . obo:GO_0051348 obo:IAO_0000115 "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." ; oboInOwl:hasExactSynonym "down regulation of transferase activity", "down-regulation of transferase activity", "downregulation of transferase activity", "transferase inhibitor" ; oboInOwl:hasNarrowSynonym "inhibition of transferase activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051348" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead." ; rdfs:label "negative regulation of transferase activity" ; rdfs:subClassOf obo:GO_0043086, obo:GO_0051338, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016740 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016740 ] ) ] . obo:GO_0051378 obo:IAO_0000115 "Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ; oboInOwl:hasExactSynonym "5-hydroxytryptamine binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0051378" ; a owl:Class ; rdfs:label "serotonin binding" ; rdfs:subClassOf obo:GO_0043176, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_350546 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_350546 ] ) ] . obo:GO_0051380 obo:IAO_0000115 "Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." ; oboInOwl:hasExactSynonym "noradrenaline binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0051380" ; a owl:Class ; rdfs:label "norepinephrine binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_72587 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0051402 obo:IAO_0000115 "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." ; oboInOwl:hasExactSynonym "apoptosis of neuronal cells", "apoptosis of neurons", "neuron programmed cell death by apoptosis", "neuronal cell apoptosis", "neuronal cell programmed cell death by apoptosis", "programmed cell death of neuronal cells by apoptosis", "programmed cell death of neurons by apoptosis", "programmed cell death, neuronal cells", "programmed cell death, neurons" ; oboInOwl:hasNarrowSynonym "neuron apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051402" ; a owl:Class ; rdfs:label "neuron apoptotic process" ; rdfs:subClassOf obo:GO_0006915, obo:GO_0070997 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0051410 obo:IAO_0000115 "Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances." ; oboInOwl:hasExactSynonym "detoxification of nitrogenous compound" ; oboInOwl:hasNarrowSynonym "nitric oxide (NO) detoxification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051410" ; a owl:Class ; rdfs:label "detoxification of nitrogen compound" ; rdfs:subClassOf obo:GO_0098754, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_1901698 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_51143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098754 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_51143 ] ) ] . obo:GO_0051445 obo:IAO_0000115 "Any process that modulates the rate or extent of progression through the meiotic cell cycle." ; oboInOwl:hasExactSynonym "meiotic cell cycle modulation", "meiotic cell cycle regulation", "modulation of meiotic cell cycle progression", "regulation of meiotic cell cycle progression", "regulation of progression through meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiotic cell cycle regulator" ; oboInOwl:id "GO:0051445" ; a owl:Class ; rdfs:label "regulation of meiotic cell cycle" ; rdfs:subClassOf obo:GO_0051726, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051446 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." ; oboInOwl:hasExactSynonym "positive regulation of meiotic cell cycle progression", "positive regulation of progression through meiotic cell cycle", "up regulation of progression through meiotic cell cycle", "up-regulation of progression through meiotic cell cycle", "upregulation of progression through meiotic cell cycle" ; oboInOwl:hasNarrowSynonym "activation of progression through meiotic cell cycle", "stimulation of progression through meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051446" ; a owl:Class ; rdfs:label "positive regulation of meiotic cell cycle" ; rdfs:subClassOf obo:GO_0045787, obo:GO_0051445, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051447 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." ; oboInOwl:hasExactSynonym "down regulation of progression through meiotic cell cycle", "down-regulation of progression through meiotic cell cycle", "downregulation of progression through meiotic cell cycle", "negative regulation of meiotic cell cycle progression", "negative regulation of progression through meiotic cell cycle" ; oboInOwl:hasNarrowSynonym "inhibition of progression through meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051447" ; a owl:Class ; rdfs:label "negative regulation of meiotic cell cycle" ; rdfs:subClassOf obo:GO_0045786, obo:GO_0051445, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051450 obo:IAO_0000115 "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051450" ; a owl:Class ; rdfs:label "myoblast proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000056 ] ) ] . obo:GO_0051451 obo:IAO_0000115 "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051451" ; a owl:Class ; rdfs:label "myoblast migration" ; rdfs:subClassOf obo:GO_0014812, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000056 ] ) ] . obo:GO_0051452 obo:IAO_0000115 "Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion." ; oboInOwl:hasExactSynonym "cell pH reduction", "cellular acidification", "reduction of cellular pH", "reduction of pH in cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intracellular acidification" ; oboInOwl:id "GO:0051452" ; a owl:Class ; rdfs:label "intracellular pH reduction" ; rdfs:subClassOf obo:GO_0051453 . obo:GO_0051453 obo:IAO_0000115 "Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion." ; oboInOwl:hasExactSynonym "cell pH regulation", "cellular pH regulation", "pH regulation in cell", "regulation of cell pH" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051453" ; a owl:Class ; rdfs:label "regulation of intracellular pH" ; rdfs:subClassOf obo:GO_0030641, obo:GO_0065008 . obo:GO_0051457 obo:IAO_0000115 "Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus." ; oboInOwl:hasExactSynonym "maintenance of nuclear protein localization", "maintenance of protein location in cell nucleus" ; oboInOwl:hasNarrowSynonym "nuclear protein retention", "nuclear protein sequestering", "nuclear protein sequestration", "protein retention in nucleus", "protein sequestration in nucleus", "protein storage in nucleus", "protein-nuclear retention", "sequestration of protein in nucleus", "storage of protein in nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "maintenance of protein localization in nucleus" ; oboInOwl:id "GO:0051457" ; a owl:Class ; rdfs:label "maintenance of protein location in nucleus" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034504 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0051469 obo:IAO_0000115 "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole." ; oboInOwl:hasAlternativeId "GO:0042146" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heterotypic vacuole fusion (non-autophagic)", "heterotypic vacuole fusion, non-autophagic" ; oboInOwl:id "GO:0051469" ; a owl:Class ; rdfs:label "vesicle fusion with vacuole" ; rdfs:subClassOf obo:GO_0006906, obo:GO_0097576, [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0031982 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0005773 ] [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0051493 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ; oboInOwl:hasExactSynonym "regulation of cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0051493" ; a owl:Class ; rdfs:label "regulation of cytoskeleton organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007010 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007010 ] ) ] . obo:GO_0051494 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ; oboInOwl:hasExactSynonym "down regulation of cytoskeleton organization", "down-regulation of cytoskeleton organization", "downregulation of cytoskeleton organization", "negative regulation of cytoskeleton organisation" ; oboInOwl:hasNarrowSynonym "inhibition of cytoskeleton organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0051494" ; a owl:Class ; rdfs:label "negative regulation of cytoskeleton organization" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0051493, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007010 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007010 ] ) ] . obo:GO_0051495 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ; oboInOwl:hasExactSynonym "positive regulation of cytoskeleton organisation", "up regulation of cytoskeleton organization", "up-regulation of cytoskeleton organization", "upregulation of cytoskeleton organization" ; oboInOwl:hasNarrowSynonym "activation of cytoskeleton organization", "stimulation of cytoskeleton organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0051495" ; a owl:Class ; rdfs:label "positive regulation of cytoskeleton organization" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0051493, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007010 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007010 ] ) ] . obo:GO_0051588 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051588" ; a owl:Class ; rdfs:label "regulation of neurotransmitter transport" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006836 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006836 ] ) ] . obo:GO_0051589 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of neurotransmitter transport", "down-regulation of neurotransmitter transport", "downregulation of neurotransmitter transport" ; oboInOwl:hasNarrowSynonym "inhibition of neurotransmitter transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051589" ; a owl:Class ; rdfs:label "negative regulation of neurotransmitter transport" ; rdfs:subClassOf obo:GO_0051051, obo:GO_0051588, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006836 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006836 ] ) ] . obo:GO_0051590 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of neurotransmitter transport", "up-regulation of neurotransmitter transport", "upregulation of neurotransmitter transport" ; oboInOwl:hasNarrowSynonym "activation of neurotransmitter transport", "stimulation of neurotransmitter transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051590" ; a owl:Class ; rdfs:label "positive regulation of neurotransmitter transport" ; rdfs:subClassOf obo:GO_0051050, obo:GO_0051588, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006836 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006836 ] ) ] . obo:GO_0051592 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus." ; oboInOwl:hasExactSynonym "response to Ca2+ ion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051592" ; a owl:Class ; rdfs:label "response to calcium ion" ; rdfs:subClassOf obo:GO_0010038, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_29108 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_29108 ] ) ] . obo:GO_0051606 obo:IAO_0000115 "The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal." ; oboInOwl:hasExactSynonym "stimulus detection" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "perception of stimulus", "stimulus sensing" ; oboInOwl:id "GO:0051606" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "detection of stimulus" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0051620 obo:IAO_0000115 "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine." ; oboInOwl:hasExactSynonym "levarterenol reuptake", "levarterenol uptake", "noradrenaline reuptake", "noradrenaline uptake", "norepinephrine import", "norepinephrine reuptake" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051620" ; a owl:Class ; rdfs:label "norepinephrine uptake" ; rdfs:subClassOf obo:GO_0015874, obo:GO_0090493 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005576 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0051621 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell." ; oboInOwl:hasExactSynonym "regulation of levarterenol uptake", "regulation of noradrenaline uptake", "regulation of norepinephrine import" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051621" ; a owl:Class ; rdfs:label "regulation of norepinephrine uptake" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051620 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051620 ] ) ] . obo:GO_0051622 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell." ; oboInOwl:hasExactSynonym "down regulation of norepinephrine uptake", "down-regulation of norepinephrine uptake", "downregulation of norepinephrine uptake", "negative regulation of levarterenol uptake", "negative regulation of noradrenaline uptake", "negative regulation of norepinephrine import" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051622" ; a owl:Class ; rdfs:label "negative regulation of norepinephrine uptake" ; rdfs:subClassOf obo:GO_0051051, obo:GO_0051621, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051620 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051620 ] ) ] . obo:GO_0051623 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell." ; oboInOwl:hasExactSynonym "positive regulation of levarterenol uptake", "positive regulation of noradrenaline uptake", "positive regulation of norepinephrine import", "up regulation of norepinephrine uptake", "up-regulation of norepinephrine uptake", "upregulation of norepinephrine uptake" ; oboInOwl:hasNarrowSynonym "activation of norepinephrine uptake", "stimulation of norepinephrine uptake" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051623" ; a owl:Class ; rdfs:label "positive regulation of norepinephrine uptake" ; rdfs:subClassOf obo:GO_0051050, obo:GO_0051621, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051620 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051620 ] ) ] . obo:GO_0051630 obo:IAO_0000115 "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ; oboInOwl:hasExactSynonym "acetylcholine import" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051630" ; a owl:Class ; rdfs:label "acetylcholine uptake" ; rdfs:subClassOf obo:GO_0015870, obo:GO_0098657 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005576 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15355 ] ) ] . obo:GO_0051631 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell." ; oboInOwl:hasExactSynonym "regulation of acetylcholine import" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051631" ; a owl:Class ; rdfs:label "regulation of acetylcholine uptake" ; rdfs:subClassOf obo:GO_0051952, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051630 ] ) ] . obo:GO_0051632 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell." ; oboInOwl:hasExactSynonym "down regulation of acetylcholine uptake", "down-regulation of acetylcholine uptake", "downregulation of acetylcholine uptake", "negative regulation of acetylcholine import" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051632" ; a owl:Class ; rdfs:label "negative regulation of acetylcholine uptake" ; rdfs:subClassOf obo:GO_0051631, obo:GO_0051953, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051630 ] ) ] . obo:GO_0051633 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell." ; oboInOwl:hasExactSynonym "positive regulation of acetylcholine import", "up regulation of acetylcholine uptake", "up-regulation of acetylcholine uptake", "upregulation of acetylcholine uptake" ; oboInOwl:hasNarrowSynonym "activation of acetylcholine uptake", "stimulation of acetylcholine uptake" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051633" ; a owl:Class ; rdfs:label "positive regulation of acetylcholine uptake" ; rdfs:subClassOf obo:GO_0051631, obo:GO_0051954, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051630 ] ) ] . obo:GO_0051640 obo:IAO_0000115 "Any process in which an organelle is transported to, and/or maintained in, a specific location." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI ; oboInOwl:hasExactSynonym "establishment and maintenance of organelle localization", "organelle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051640" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "organelle localization" ; rdfs:subClassOf obo:GO_0051179, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0043226 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0051641 obo:IAO_0000115 "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-18T14:04:32Z" ; oboInOwl:hasAlternativeId "GO:1902580" ; oboInOwl:hasExactSynonym "cellular localisation", "establishment and maintenance of cellular localization", "establishment and maintenance of localization in cell or cell membrane", "single organism cellular localization" ; oboInOwl:hasNarrowSynonym "intracellular localization", "localization within cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism cellular localization" ; oboInOwl:id "GO:0051641" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular localization" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0051179 . obo:GO_0051645 obo:IAO_0000115 "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell." ; oboInOwl:hasExactSynonym "Golgi apparatus localization", "Golgi body localization", "Golgi localisation", "establishment and maintenance of Golgi localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051645" ; a owl:Class ; rdfs:label "Golgi localization" ; rdfs:subClassOf obo:GO_0051640, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005794 ] ) ] . obo:GO_0051647 obo:IAO_0000115 "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." ; oboInOwl:hasExactSynonym "cell nucleus localization", "establishment and maintenance of nucleus localization", "localization of nucleus", "nucleus localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051647" ; a owl:Class ; rdfs:label "nucleus localization" ; rdfs:subClassOf obo:GO_0051640, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0051648 obo:IAO_0000115 "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." ; oboInOwl:hasExactSynonym "cytoplasmic vesicle localization", "establishment and maintenance of vesicle localization", "vesicle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051648" ; a owl:Class ; rdfs:label "vesicle localization" ; rdfs:subClassOf obo:GO_0051640, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0031982 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0051649 obo:IAO_0000115 "Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." ; oboInOwl:hasExactSynonym "establishment of localisation in cell" ; oboInOwl:hasNarrowSynonym "establishment of intracellular localization", "establishment of localization within cell", "positioning within cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "establishment of cellular localization" ; oboInOwl:id "GO:0051649" ; a owl:Class ; rdfs:label "establishment of localization in cell" ; rdfs:subClassOf obo:GO_0051234, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051641 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000000 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_131567 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_131567 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051234 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000000 ] ) ] . obo:GO_0051650 obo:IAO_0000115 "The directed movement of a vesicle to a specific location." ; oboInOwl:hasExactSynonym "establishment of vesicle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051650" ; a owl:Class ; rdfs:label "establishment of vesicle localization" ; rdfs:subClassOf obo:GO_0051648, obo:GO_0051649, obo:GO_0051656 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051234 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0051651 obo:IAO_0000115 "Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." ; oboInOwl:hasNarrowSynonym "cellular retention", "cellular sequestering", "cellular storage", "intracellular retention", "intracellular sequestering", "intracellular storage", "maintenance of intracellular localization", "maintenance of localization within cell", "retention within cell", "sequestering within cell", "storage within cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "maintenance of cellular localization", "maintenance of localization in cell" ; oboInOwl:id "GO:0051651" ; a owl:Class ; rdfs:label "maintenance of location in cell" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0051235, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051641 ] . obo:GO_0051653 obo:IAO_0000115 "Any process in which is the spindle is transported to, and/or maintained in, a specific location." ; oboInOwl:hasExactSynonym "establishment and maintenance of spindle localization", "spindle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051653" ; a owl:Class ; rdfs:label "spindle localization" ; rdfs:subClassOf obo:GO_0022402, obo:GO_0051640 . obo:GO_0051656 obo:IAO_0000115 "The directed movement of an organelle to a specific location." ; oboInOwl:hasExactSynonym "establishment of organelle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051656" ; a owl:Class ; rdfs:label "establishment of organelle localization" ; rdfs:subClassOf obo:GO_0051234, obo:GO_0051640 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051234 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0051668 obo:IAO_0000115 "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane." ; oboInOwl:hasExactSynonym "establishment and maintenance of localization in membrane", "establishment and maintenance of position in membrane", "localisation within membrane", "localization to membrane" ; oboInOwl:hasNarrowSynonym "positioning within membrane" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051668" ; a owl:Class ; rdfs:label "localization within membrane" ; rdfs:subClassOf obo:GO_0051641, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0051673 obo:IAO_0000115 "The disruption of the cell membrane of another organism, leading to damage or temporary subversion of the membrane." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24079"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0044662" ; oboInOwl:hasBroadSynonym "disruption of membrane integrity in another organism" ; oboInOwl:hasExactSynonym "disruption by organism of host cell membrane", "membrane disruption in other organism" ; oboInOwl:hasNarrowSynonym "cytolysis, by membrane disruption, in other organism", "disruption by virus of host cell membrane" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "membrane disruption in another organism" ; oboInOwl:id "GO:0051673" ; a owl:Class ; rdfs:label "perturbation of plasma membrane integrity in another organism" ; rdfs:subClassOf obo:GO_0140975 . obo:GO_0051674 obo:IAO_0000115 "Any process in which a cell is transported to, and/or maintained in, a specific location." ; oboInOwl:hasExactSynonym "cell localization", "establishment and maintenance of cell localization", "establishment and maintenance of localization of cell", "localisation of cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051674" ; a owl:Class ; rdfs:label "localization of cell" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0051179, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CL_0000000 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CL_0000000 ] ) ] . obo:GO_0051683 obo:IAO_0000115 "The directed movement of the Golgi to a specific location." ; oboInOwl:hasExactSynonym "establishment of Golgi apparatus localization", "establishment of Golgi body localization", "establishment of Golgi localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051683" ; a owl:Class ; rdfs:label "establishment of Golgi localization" ; rdfs:subClassOf obo:GO_0051645, obo:GO_0051649, obo:GO_0051656 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051234 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0005794 ] ) ] . obo:GO_0051703 obo:IAO_0000115 "Any process in which an organism has an effect on an organism of the same species." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20191"^^xsd:anyURI ; oboInOwl:hasExactSynonym "intraspecies interaction between organisms", "intraspecies interaction with other organisms" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051703" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:label "biological process involved in intraspecies interaction between organisms" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0051707 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." ; oboInOwl:hasAlternativeId "GO:0009613", "GO:0042828" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051707" ; a owl:Class ; rdfs:label "response to other organism" ; rdfs:subClassOf obo:GO_0043207, obo:GO_0044419 . obo:GO_0051716 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051716" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to stimulus" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0050896 . obo:GO_0051726 obo:IAO_0000115 "Any process that modulates the rate or extent of progression through the cell cycle." ; oboInOwl:hasAlternativeId "GO:0000074", "GO:0007050", "GO:0071156", "GO:0071157", "GO:0071158", "GO:0071850" ; oboInOwl:hasExactSynonym "cell cycle modulation", "cell cycle regulation", "control of cell cycle progression", "modulation of cell cycle progression", "regulation of cell cycle progression", "regulation of progression through cell cycle" ; oboInOwl:hasNarrowSynonym "arrest of mitotic cell cycle progression", "cell cycle arrest", "mitotic cell cycle arrest", "negative regulation of cell cycle arrest", "positive regulation of cell cycle arrest", "regulation of cell cycle arrest" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell cycle regulator", "tumor suppressor" ; oboInOwl:id "GO:0051726" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of cell cycle" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0051781 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell division." ; oboInOwl:hasExactSynonym "up regulation of cell division", "up-regulation of cell division", "upregulation of cell division" ; oboInOwl:hasNarrowSynonym "activation of cell division", "stimulation of cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051781" ; a owl:Class ; rdfs:label "positive regulation of cell division" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0051302, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051301 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051301 ] ) ] . obo:GO_0051782 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." ; oboInOwl:hasExactSynonym "down regulation of cell division", "down-regulation of cell division", "downregulation of cell division" ; oboInOwl:hasNarrowSynonym "inhibition of cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051782" ; a owl:Class ; rdfs:label "negative regulation of cell division" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0051302, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051301 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051301 ] ) ] . obo:GO_0051783 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051783" ; a owl:Class ; rdfs:label "regulation of nuclear division" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000280 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000280 ] ) ] . obo:GO_0051784 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ; oboInOwl:hasExactSynonym "down regulation of nuclear division", "down-regulation of nuclear division", "downregulation of nuclear division" ; oboInOwl:hasNarrowSynonym "inhibition of nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051784" ; a owl:Class ; rdfs:label "negative regulation of nuclear division" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0051783, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000280 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000280 ] ) ] . obo:GO_0051785 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ; oboInOwl:hasExactSynonym "up regulation of nuclear division", "up-regulation of nuclear division", "upregulation of nuclear division" ; oboInOwl:hasNarrowSynonym "activation of nuclear division", "stimulation of nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051785" ; a owl:Class ; rdfs:label "positive regulation of nuclear division" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0051783, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000280 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000280 ] ) ] . obo:GO_0051875 obo:IAO_0000115 "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell." ; oboInOwl:hasExactSynonym "pigment granule localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051875" ; a owl:Class ; rdfs:label "pigment granule localization" ; rdfs:subClassOf obo:GO_0051648, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033059 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0048770 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051179 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0048770 ] ) ] . obo:GO_0051890 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051890" ; a owl:Class ; rdfs:label "regulation of cardioblast differentiation" ; rdfs:subClassOf obo:GO_1905207, obo:GO_2000736, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010002 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010002 ] ) ] . obo:GO_0051891 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ; oboInOwl:hasExactSynonym "up regulation of cardioblast differentiation", "up-regulation of cardioblast differentiation", "upregulation of cardioblast differentiation" ; oboInOwl:hasNarrowSynonym "activation of cardioblast differentiation", "stimulation of cardioblast differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051891" ; a owl:Class ; rdfs:label "positive regulation of cardioblast differentiation" ; rdfs:subClassOf obo:GO_0051890, obo:GO_1905209, obo:GO_2000738, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010002 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010002 ] ) ] . obo:GO_0051892 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating." ; oboInOwl:hasExactSynonym "down regulation of cardioblast differentiation", "down-regulation of cardioblast differentiation", "downregulation of cardioblast differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of cardioblast differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051892" ; a owl:Class ; rdfs:label "negative regulation of cardioblast differentiation" ; rdfs:subClassOf obo:GO_0051890, obo:GO_1905208, obo:GO_2000737, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010002 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010002 ] ) ] . obo:GO_0051904 obo:IAO_0000115 "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "pigment granule translocation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051904" ; a owl:Class ; rdfs:label "pigment granule transport" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0051875, obo:GO_0051905 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0048770 ] ) ] . obo:GO_0051905 obo:IAO_0000115 "The directed movement of a pigment granule to a specific location." ; oboInOwl:hasExactSynonym "establishment of pigment granule localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051905" ; a owl:Class ; rdfs:label "establishment of pigment granule localization" ; rdfs:subClassOf obo:GO_0051650, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051875 ] . obo:GO_0051924 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "regulation of calcium transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051924" ; a owl:Class ; rdfs:label "regulation of calcium ion transport" ; rdfs:subClassOf obo:GO_0010959, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006816 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006816 ] ) ] . obo:GO_0051926 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of calcium ion transport", "down-regulation of calcium ion transport", "downregulation of calcium ion transport", "negative regulation of calcium transport" ; oboInOwl:hasNarrowSynonym "inhibition of calcium ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051926" ; a owl:Class ; rdfs:label "negative regulation of calcium ion transport" ; rdfs:subClassOf obo:GO_0043271, obo:GO_0051924, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006816 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006816 ] ) ] . obo:GO_0051928 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "positive regulation of calcium transport", "up regulation of calcium ion transport", "up-regulation of calcium ion transport", "upregulation of calcium ion transport" ; oboInOwl:hasNarrowSynonym "activation of calcium ion transport", "stimulation of calcium ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051928" ; a owl:Class ; rdfs:label "positive regulation of calcium ion transport" ; rdfs:subClassOf obo:GO_0043270, obo:GO_0051924, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006816 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006816 ] ) ] . obo:GO_0051930 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051930" ; a owl:Class ; rdfs:label "regulation of sensory perception of pain" ; rdfs:subClassOf obo:GO_0051931, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019233 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019233 ] ) ] . obo:GO_0051931 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051931" ; a owl:Class ; rdfs:label "regulation of sensory perception" ; rdfs:subClassOf obo:GO_0031644, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007600 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007600 ] ) ] . obo:GO_0051932 obo:IAO_0000115 "The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; oboInOwl:hasExactSynonym "GABAergic synaptic transmission", "synaptic transmission, GABA mediated", "synaptic transmission, gamma-aminobutyric acid mediated", "synaptic transmission, gamma-aminobutyric acid-ergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051932" ; a owl:Class ; rdfs:label "synaptic transmission, GABAergic" ; rdfs:subClassOf obo:GO_0007268, [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:CHEBI_59888 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000057 ; owl:someValuesFrom obo:CL_0000617 ] . obo:GO_0051937 obo:IAO_0000115 "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051937" ; a owl:Class ; rdfs:label "catecholamine transport" ; rdfs:subClassOf obo:GO_0015844, obo:GO_0015850, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33567 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33567 ] ) ] . obo:GO_0051952 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051952" ; a owl:Class ; rdfs:label "regulation of amine transport" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015837 ] ) ] . obo:GO_0051953 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of amine transport", "down-regulation of amine transport", "downregulation of amine transport" ; oboInOwl:hasNarrowSynonym "inhibition of amine transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051953" ; a owl:Class ; rdfs:label "negative regulation of amine transport" ; rdfs:subClassOf obo:GO_0051051, obo:GO_0051952, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015837 ] ) ] . obo:GO_0051954 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of amine transport", "up-regulation of amine transport", "upregulation of amine transport" ; oboInOwl:hasNarrowSynonym "activation of amine transport", "stimulation of amine transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051954" ; a owl:Class ; rdfs:label "positive regulation of amine transport" ; rdfs:subClassOf obo:GO_0051050, obo:GO_0051952, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015837 ] ) ] . obo:GO_0051955 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051955" ; a owl:Class ; rdfs:label "regulation of amino acid transport" ; rdfs:subClassOf obo:GO_0032890, obo:GO_0051952, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006865 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006865 ] ) ] . obo:GO_0051956 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of amino acid transport", "down-regulation of amino acid transport", "downregulation of amino acid transport", "negative regulation of amino acid transmembrane transport" ; oboInOwl:hasNarrowSynonym "inhibition of amino acid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051956" ; a owl:Class ; rdfs:label "negative regulation of amino acid transport" ; rdfs:subClassOf obo:GO_0032891, obo:GO_0051953, obo:GO_0051955, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006865 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006865 ] ) ] . obo:GO_0051957 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "positive regulation of amino acid transmembrane transport", "up regulation of amino acid transport", "up-regulation of amino acid transport", "upregulation of amino acid transport" ; oboInOwl:hasNarrowSynonym "activation of amino acid transport", "stimulation of amino acid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051957" ; a owl:Class ; rdfs:label "positive regulation of amino acid transport" ; rdfs:subClassOf obo:GO_0032892, obo:GO_0051954, obo:GO_0051955, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006865 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006865 ] ) ] . obo:GO_0051960 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051960" ; a owl:Class ; rdfs:label "regulation of nervous system development" ; rdfs:subClassOf obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007399 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007399 ] ) ] . obo:GO_0051961 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ; oboInOwl:hasExactSynonym "down regulation of nervous system development", "down-regulation of nervous system development", "downregulation of nervous system development" ; oboInOwl:hasNarrowSynonym "inhibition of nervous system development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051961" ; a owl:Class ; rdfs:label "negative regulation of nervous system development" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0051241, obo:GO_0051960, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007399 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007399 ] ) ] . obo:GO_0051962 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ; oboInOwl:hasExactSynonym "up regulation of nervous system development", "up-regulation of nervous system development", "upregulation of nervous system development" ; oboInOwl:hasNarrowSynonym "activation of nervous system development", "stimulation of nervous system development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051962" ; a owl:Class ; rdfs:label "positive regulation of nervous system development" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0051240, obo:GO_0051960, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007399 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007399 ] ) ] . obo:GO_0051963 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ; oboInOwl:hasExactSynonym "regulation of synapse biogenesis", "regulation of synaptogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051963" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of synapse assembly" ; rdfs:subClassOf obo:GO_0050807, obo:GO_1901888, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007416 ] ) ] . obo:GO_0051964 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ; oboInOwl:hasExactSynonym "down regulation of synapse assembly", "down-regulation of synapse assembly", "downregulation of synapse assembly", "negative regulation of synapse biogenesis", "negative regulation of synaptogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of synapse assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051964" ; a owl:Class ; rdfs:label "negative regulation of synapse assembly" ; rdfs:subClassOf obo:GO_0051961, obo:GO_0051963, obo:GO_1901889, obo:GO_1905809, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007416 ] ) ] . obo:GO_0051965 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ; oboInOwl:hasExactSynonym "positive regulation of synapse biogenesis", "positive regulation of synaptogenesis", "up regulation of synapse assembly", "up-regulation of synapse assembly", "upregulation of synapse assembly" ; oboInOwl:hasNarrowSynonym "activation of synapse assembly", "stimulation of synapse assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051965" ; a owl:Class ; rdfs:label "positive regulation of synapse assembly" ; rdfs:subClassOf obo:GO_0051962, obo:GO_0051963, obo:GO_1901890, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007416 ] ) ] . obo:GO_0051969 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." ; oboInOwl:hasExactSynonym "regulation of conduction of nerve impulse" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051969" ; a owl:Class ; rdfs:label "regulation of transmission of nerve impulse" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0031644, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019226 ] ) ] . obo:GO_0051970 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." ; oboInOwl:hasExactSynonym "down regulation of transmission of nerve impulse", "down-regulation of transmission of nerve impulse", "downregulation of transmission of nerve impulse", "negative regulation of conduction of nerve impulse" ; oboInOwl:hasNarrowSynonym "inhibition of transmission of nerve impulse" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051970" ; a owl:Class ; rdfs:label "negative regulation of transmission of nerve impulse" ; rdfs:subClassOf obo:GO_0010648, obo:GO_0031645, obo:GO_0051969, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019226 ] ) ] . obo:GO_0051971 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation." ; oboInOwl:hasExactSynonym "positive regulation of conduction of nerve impulse", "up regulation of transmission of nerve impulse", "up-regulation of transmission of nerve impulse", "upregulation of transmission of nerve impulse" ; oboInOwl:hasNarrowSynonym "activation of transmission of nerve impulse", "stimulation of transmission of nerve impulse" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051971" ; a owl:Class ; rdfs:label "positive regulation of transmission of nerve impulse" ; rdfs:subClassOf obo:GO_0010647, obo:GO_0031646, obo:GO_0051969, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019226 ] ) ] . obo:GO_0051983 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051983" ; a owl:Class ; rdfs:label "regulation of chromosome segregation" ; rdfs:subClassOf obo:GO_0010564, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007059 ] ) ] . obo:GO_0051984 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ; oboInOwl:hasExactSynonym "up regulation of chromosome segregation", "up-regulation of chromosome segregation", "upregulation of chromosome segregation" ; oboInOwl:hasNarrowSynonym "activation of chromosome segregation", "stimulation of chromosome segregation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051984" ; a owl:Class ; rdfs:label "positive regulation of chromosome segregation" ; rdfs:subClassOf obo:GO_0051983, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007059 ] ) ] . obo:GO_0051985 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ; oboInOwl:hasExactSynonym "down regulation of chromosome segregation", "down-regulation of chromosome segregation", "downregulation of chromosome segregation" ; oboInOwl:hasNarrowSynonym "inhibition of chromosome segregation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051985" ; a owl:Class ; rdfs:label "negative regulation of chromosome segregation" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0051983, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007059 ] ) ] . obo:GO_0052689 obo:IAO_0000115 "Catalysis of the hydrolysis of a carboxylic ester bond." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24654"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0004091", "GO:0004302", "GO:0004759", "GO:0016789" ; oboInOwl:hasDbXref "EC:3.1.1.-", "KEGG_REACTION:R00630", "Reactome:R-HSA-5693691", "Reactome:R-HSA-8937442", "Reactome:R-HSA-9749792", "UM-BBD_reactionID:r1025" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "carboxylate esterase activity", "carboxylic esterase activity", "hydrolase activity acting on ester bonds" ; oboInOwl:id "GO:0052689" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "carboxylic ester hydrolase activity" ; rdfs:subClassOf obo:GO_0016788 . obo:GO_0055001 obo:IAO_0000115 "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." ; oboInOwl:hasAlternativeId "GO:0048747" ; oboInOwl:hasExactSynonym "muscle fiber development", "muscle fibre development", "myofiber development", "myofibre development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055001" ; a owl:Class ; rdfs:label "muscle cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042692 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000187 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000187 ] ) ] . obo:GO_0055002 obo:IAO_0000115 "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055002" ; a owl:Class ; rdfs:label "striated muscle cell development" ; rdfs:subClassOf obo:GO_0055001, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051146 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000737 ] ) ] . obo:GO_0055003 obo:IAO_0000115 "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells." ; oboInOwl:hasExactSynonym "cardiac myofibril development", "cardiac myofibril morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heart myofibril assembly" ; oboInOwl:id "GO:0055003" ; a owl:Class ; rdfs:label "cardiac myofibril assembly" ; rdfs:subClassOf obo:GO_0030239, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055013 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0097512 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0097512 ] ) ] . obo:GO_0055006 obo:IAO_0000115 "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual." ; oboInOwl:hasExactSynonym "cardiocyte development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heart cell development" ; oboInOwl:id "GO:0055006" ; a owl:Class ; rdfs:label "cardiac cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035051 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002494 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002494 ] ) ] . obo:GO_0055007 obo:IAO_0000115 "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction." ; oboInOwl:hasExactSynonym "cardiomyocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heart muscle cell differentiation" ; oboInOwl:id "GO:0055007" ; a owl:Class ; rdfs:label "cardiac muscle cell differentiation" ; rdfs:subClassOf obo:GO_0035051, obo:GO_0051146, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048738 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000746 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000746 ] ) ] . obo:GO_0055008 obo:IAO_0000115 "The process in which the anatomical structures of cardiac muscle tissue are generated and organized." ; oboInOwl:hasBroadSynonym "myocardium morphogenesis" ; oboInOwl:hasExactSynonym "heart muscle morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055008" ; a owl:Class ; rdfs:label "cardiac muscle tissue morphogenesis" ; rdfs:subClassOf obo:GO_0060415, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048738 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001133 ] ) ] . obo:GO_0055009 obo:IAO_0000115 "The process in which the anatomical structure of cardiac atrium muscle is generated and organized." ; oboInOwl:hasExactSynonym "atrial heart muscle morphogenesis", "atrial myocardium morphogenesis", "cardiac atrium muscle morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055009" ; a owl:Class ; rdfs:label "atrial cardiac muscle tissue morphogenesis" ; rdfs:subClassOf obo:GO_0055008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003209 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003228 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004490 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004490 ] ) ] . obo:GO_0055010 obo:IAO_0000115 "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized." ; oboInOwl:hasExactSynonym "cardiac ventricle muscle morphogenesis", "ventricular heart muscle morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055010" ; a owl:Class ; rdfs:label "ventricular cardiac muscle tissue morphogenesis" ; rdfs:subClassOf obo:GO_0055008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003208 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003229 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0018649 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0018649 ] ) ] . obo:GO_0055013 obo:IAO_0000115 "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state." ; oboInOwl:hasAlternativeId "GO:0048739" ; oboInOwl:hasExactSynonym "cardiac muscle fiber development", "cardiac muscle fibre development", "cardiomyocyte cell development", "heart muscle cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heart muscle fiber development" ; oboInOwl:id "GO:0055013" ; a owl:Class ; rdfs:label "cardiac muscle cell development" ; rdfs:subClassOf obo:GO_0055002, obo:GO_0055006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055007 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000746 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000746 ] ) ] . obo:GO_0055017 obo:IAO_0000115 "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." ; oboInOwl:hasExactSynonym "heart muscle growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055017" ; a owl:Class ; rdfs:label "cardiac muscle tissue growth" ; rdfs:subClassOf obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048738 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060419 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0001133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0001133 ] ) ] . obo:GO_0055018 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development." ; oboInOwl:hasExactSynonym "regulation of cardiac muscle fibre development", "regulation of heart muscle fiber development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055018" ; a owl:Class ; rdfs:label "regulation of cardiac muscle fiber development" ; rdfs:subClassOf obo:GO_0060284, obo:GO_2000725, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0055013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0055013 ] ) ] . obo:GO_0055019 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development." ; oboInOwl:hasExactSynonym "down regulation of cardiac muscle fiber development", "down-regulation of cardiac muscle fiber development", "downregulation of cardiac muscle fiber development", "negative regulation of cardiac muscle fibre development" ; oboInOwl:hasNarrowSynonym "inhibition of cardiac muscle fiber development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of heart muscle fiber development" ; oboInOwl:id "GO:0055019" ; a owl:Class ; rdfs:label "negative regulation of cardiac muscle fiber development" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0051154, obo:GO_0055018, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0055013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0055013 ] ) ] . obo:GO_0055020 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development." ; oboInOwl:hasExactSynonym "positive regulation of cardiac muscle fibre development", "positive regulation of heart muscle fiber development", "up regulation of cardiac muscle fiber development", "up-regulation of cardiac muscle fiber development", "upregulation of cardiac muscle fiber development" ; oboInOwl:hasNarrowSynonym "activation of cardiac muscle fiber development", "stimulation of cardiac muscle fiber development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055020" ; a owl:Class ; rdfs:label "positive regulation of cardiac muscle fiber development" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0055018, obo:GO_2000727, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0055013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0055013 ] ) ] . obo:GO_0055021 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cardiac muscle growth." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055021" ; a owl:Class ; rdfs:label "regulation of cardiac muscle tissue growth" ; rdfs:subClassOf obo:GO_0060420, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0055017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0055017 ] ) ] . obo:GO_0055022 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth." ; oboInOwl:hasExactSynonym "down regulation of cardiac muscle growth", "down-regulation of cardiac muscle growth", "downregulation of cardiac muscle growth" ; oboInOwl:hasNarrowSynonym "inhibition of cardiac muscle growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of heart muscle growth" ; oboInOwl:id "GO:0055022" ; a owl:Class ; rdfs:label "negative regulation of cardiac muscle tissue growth" ; rdfs:subClassOf obo:GO_0055021, obo:GO_0061117, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0055017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0055017 ] ) ] . obo:GO_0055023 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth." ; oboInOwl:hasExactSynonym "positive regulation of heart muscle growth", "up regulation of cardiac muscle growth", "up-regulation of cardiac muscle growth", "upregulation of cardiac muscle growth" ; oboInOwl:hasNarrowSynonym "activation of cardiac muscle growth", "stimulation of cardiac muscle growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055023" ; a owl:Class ; rdfs:label "positive regulation of cardiac muscle tissue growth" ; rdfs:subClassOf obo:GO_0055021, obo:GO_0060421, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0055017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0055017 ] ) ] . obo:GO_0055024 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development." ; oboInOwl:hasExactSynonym "regulation of heart muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055024" ; a owl:Class ; rdfs:label "regulation of cardiac muscle tissue development" ; rdfs:subClassOf obo:GO_0016202, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048738 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048738 ] ) ] . obo:GO_0055025 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development." ; oboInOwl:hasExactSynonym "positive regulation of heart muscle development", "up regulation of cardiac muscle development", "up-regulation of cardiac muscle development", "upregulation of cardiac muscle development" ; oboInOwl:hasNarrowSynonym "activation of cardiac muscle development", "stimulation of cardiac muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055025" ; a owl:Class ; rdfs:label "positive regulation of cardiac muscle tissue development" ; rdfs:subClassOf obo:GO_0045844, obo:GO_0055024, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048738 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048738 ] ) ] . obo:GO_0055026 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development." ; oboInOwl:hasExactSynonym "down regulation of cardiac muscle development", "down-regulation of cardiac muscle development", "downregulation of cardiac muscle development", "negative regulation of heart muscle development" ; oboInOwl:hasNarrowSynonym "inhibition of cardiac muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055026" ; a owl:Class ; rdfs:label "negative regulation of cardiac muscle tissue development" ; rdfs:subClassOf obo:GO_0045843, obo:GO_0055024, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048738 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048738 ] ) ] . obo:GO_0055037 obo:IAO_0000115 "An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane." ; oboInOwl:hasExactSynonym "endosomal recycling compartment" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "ERC", "endosome recycling compartment" ; oboInOwl:id "GO:0055037" ; a owl:Class ; rdfs:label "recycling endosome" ; rdfs:subClassOf obo:GO_0005768 . obo:GO_0055057 obo:IAO_0000115 "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron." ; oboInOwl:hasExactSynonym "neuroblast cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055057" ; a owl:Class ; rdfs:label "neuroblast division" ; rdfs:subClassOf obo:GO_0051301, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007405 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051301 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000031 ] ) ] . obo:GO_0055059 obo:IAO_0000115 "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055059" ; a owl:Class ; rdfs:label "asymmetric neuroblast division" ; rdfs:subClassOf obo:GO_0008356, obo:GO_0045165, obo:GO_0055057 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008356 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000031 ] ) ] . obo:GO_0055062 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055062" ; a owl:Class ; rdfs:label "phosphate ion homeostasis" ; rdfs:subClassOf obo:GO_0098771, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_35780 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_35780 ] ) ] . obo:GO_0055063 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell." ; oboInOwl:hasAlternativeId "GO:0080174" ; oboInOwl:hasExactSynonym "sulfate homeostasis", "sulphate ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055063" ; a owl:Class ; rdfs:label "sulfate ion homeostasis" ; rdfs:subClassOf obo:GO_0098771, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_16189 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_16189 ] ) ] . obo:GO_0055074 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell." ; oboInOwl:hasExactSynonym "regulation of calcium ion concentration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055074" ; a owl:Class ; rdfs:label "calcium ion homeostasis" ; rdfs:subClassOf obo:GO_0055080, obo:GO_0098771, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_29108 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_29108 ] ) ] . obo:GO_0055078 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055078" ; a owl:Class ; rdfs:label "sodium ion homeostasis" ; rdfs:subClassOf obo:GO_0055080, obo:GO_0098771, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_29101 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_29101 ] ) ] . obo:GO_0055080 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "cation homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055080" ; a owl:Class ; rdfs:label "monoatomic cation homeostasis" ; rdfs:subClassOf obo:GO_0050801, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_23906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_23906 ] ) ] . obo:GO_0055082 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24514"^^xsd:anyURI ; oboInOwl:hasExactSynonym "cellular chemical homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055082" ; a owl:Class ; rdfs:label "intracellular chemical homeostasis" ; rdfs:subClassOf obo:GO_0019725, obo:GO_0048878 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019725 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_24431 ] ) ] . obo:GO_0055085 obo:IAO_0000115 "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2015-10-21T13:22:47Z" ; oboInOwl:hasAlternativeId "GO:0090662" ; oboInOwl:hasExactSynonym "membrane transport" ; oboInOwl:hasNarrowSynonym "ATP hydrolysis coupled transmembrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055085" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:comment "Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "transmembrane transport" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0055086 obo:IAO_0000115 "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide." ; oboInOwl:hasExactSynonym "nucleobase, nucleoside and nucleotide metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nucleobase, nucleoside and nucleotide metabolic process" ; oboInOwl:id "GO:0055086" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "nucleobase-containing small molecule metabolic process" ; rdfs:subClassOf obo:GO_0006139, obo:GO_0044281 . obo:GO_0055088 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of lipid within an organism or cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055088" ; a owl:Class ; rdfs:label "lipid homeostasis" ; rdfs:subClassOf obo:GO_0048878, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0055107 obo:IAO_0000115 "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055107" ; a owl:Class ; rdfs:label "Golgi to secretory granule transport" ; rdfs:subClassOf obo:GO_0046907, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005794 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0030141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0030141 ] ) ] . obo:GO_0055108 obo:IAO_0000115 "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055108" ; a owl:Class ; rdfs:label "Golgi to transport vesicle transport" ; rdfs:subClassOf obo:GO_0046907, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048193 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005794 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0030133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0030133 ] ) ] . obo:GO_0055111 obo:IAO_0000115 "The migration of individual cells into the embryo involved in deuterostomic gastrulation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055111" ; a owl:Class ; rdfs:label "ingression involved in gastrulation with mouth forming second" ; rdfs:subClassOf obo:GO_0042074, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001702 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001667 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001702 ] ) ] . obo:GO_0055115 obo:IAO_0000115 "The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." ; oboInOwl:hasDbXref "Wikipedia:Diapause" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055115" ; a owl:Class ; rdfs:label "entry into diapause" ; rdfs:subClassOf obo:GO_0022611 . obo:GO_0055117 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cardiac muscle contraction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055117" ; a owl:Class ; rdfs:label "regulation of cardiac muscle contraction" ; rdfs:subClassOf obo:GO_0006942, obo:GO_0008016, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060048 ] ) ] . obo:GO_0055118 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055118" ; a owl:Class ; rdfs:label "negative regulation of cardiac muscle contraction" ; rdfs:subClassOf obo:GO_0045822, obo:GO_0045988, obo:GO_0055117, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060048 ] ) ] . obo:GO_0055123 obo:IAO_0000115 "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055123" ; a owl:Class ; rdfs:label "digestive system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001007 ] ) ] . obo:GO_0060008 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060008" ; a owl:Class ; rdfs:label "Sertoli cell differentiation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0030855, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008584 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000216 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000216 ] ) ] . obo:GO_0060009 obo:IAO_0000115 "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060009" ; a owl:Class ; rdfs:label "Sertoli cell development" ; rdfs:subClassOf obo:GO_0002064, obo:GO_0003006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060008 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000216 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000216 ] ) ] . obo:GO_0060011 obo:IAO_0000115 "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060011" ; a owl:Class ; rdfs:label "Sertoli cell proliferation" ; rdfs:subClassOf obo:GO_0022414, obo:GO_0050673, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008584 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000216 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000216 ] ) ] . obo:GO_0060037 obo:IAO_0000115 "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060037" ; a owl:Class ; rdfs:label "pharyngeal system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043009 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0008814 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0008814 ] ) ] . obo:GO_0060038 obo:IAO_0000115 "The expansion of a cardiac muscle cell population by cell division." ; oboInOwl:hasExactSynonym "cardiac myocyte proliferation", "heart muscle cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiomyocyte proliferation" ; oboInOwl:id "GO:0060038" ; a owl:Class ; rdfs:label "cardiac muscle cell proliferation" ; rdfs:subClassOf obo:GO_0014855, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055017 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000746 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000746 ] ) ] . obo:GO_0060039 obo:IAO_0000115 "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060039" ; a owl:Class ; rdfs:label "pericardium development" ; rdfs:subClassOf obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002407 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002407 ] ) ] . obo:GO_0060041 obo:IAO_0000115 "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates." ; oboInOwl:hasAlternativeId "GO:0002073" ; oboInOwl:hasExactSynonym "retina development in camera-style eye" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "retinal development" ; oboInOwl:id "GO:0060041" ; a owl:Class ; rdfs:label "retina development in camera-type eye" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043010 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000966 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043010 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000966 ] ) ] . obo:GO_0060042 obo:IAO_0000115 "The process in which the anatomical structure of the retina is generated and organized." ; oboInOwl:hasExactSynonym "retina morphogenesis in camera-style eye", "retinogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060042" ; a owl:Class ; rdfs:label "retina morphogenesis in camera-type eye" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048593 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060041 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000966 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000966 ] ) ] . obo:GO_0060043 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation." ; oboInOwl:hasExactSynonym "regulation of heart muscle cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cardiomyocyte proliferation" ; oboInOwl:id "GO:0060043" ; a owl:Class ; rdfs:label "regulation of cardiac muscle cell proliferation" ; rdfs:subClassOf obo:GO_0042127, obo:GO_0055021, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060038 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060038 ] ) ] . obo:GO_0060044 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation." ; oboInOwl:hasExactSynonym "negative regulation of heart muscle cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060044" ; a owl:Class ; rdfs:label "negative regulation of cardiac muscle cell proliferation" ; rdfs:subClassOf obo:GO_0008285, obo:GO_0055022, obo:GO_0060043, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060038 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060038 ] ) ] . obo:GO_0060045 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of heart muscle cell proliferation" ; oboInOwl:id "GO:0060045" ; a owl:Class ; rdfs:label "positive regulation of cardiac muscle cell proliferation" ; rdfs:subClassOf obo:GO_0008284, obo:GO_0055023, obo:GO_0060043, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060038 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060038 ] ) ] . obo:GO_0060047 obo:IAO_0000115 "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body." ; oboInOwl:hasExactSynonym "heart beating" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiac contraction", "hemolymph circulation" ; oboInOwl:id "GO:0060047" ; a owl:Class ; rdfs:label "heart contraction" ; rdfs:subClassOf obo:GO_0003015, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008015 ] . obo:GO_0060048 obo:IAO_0000115 "Muscle contraction of cardiac muscle tissue." ; oboInOwl:hasExactSynonym "heart muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060048" ; a owl:Class ; rdfs:label "cardiac muscle contraction" ; rdfs:subClassOf obo:GO_0006941, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060047 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006936 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0001133 ] ) ] . obo:GO_0060065 obo:IAO_0000115 "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "Mullerian tract development" ; oboInOwl:id "GO:0060065" ; a owl:Class ; rdfs:label "uterus development" ; rdfs:subClassOf obo:GO_0048513, obo:GO_0048608, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000995 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000995 ] ) ] . obo:GO_0060066 obo:IAO_0000115 "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism." ; oboInOwl:hasNarrowSynonym "fallopian tube development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "Mullerian tract development" ; oboInOwl:id "GO:0060066" ; a owl:Class ; rdfs:label "oviduct development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0048608, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003889 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003889 ] ) ] . obo:GO_0060073 obo:IAO_0000115 "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body." ; oboInOwl:hasDbXref "Wikipedia:Urination" ; oboInOwl:hasExactSynonym "urination", "urine voiding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060073" ; a owl:Class ; rdfs:label "micturition" ; rdfs:subClassOf obo:GO_0003014, obo:GO_0007588 . obo:GO_0060083 obo:IAO_0000115 "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "smooth muscle contraction involved in urination", "urinary bladder smooth muscle contraction involved in micturition" ; oboInOwl:id "GO:0060083" ; a owl:Class ; rdfs:label "smooth muscle contraction involved in micturition" ; rdfs:subClassOf obo:GO_0014832, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060073 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006939 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060073 ] ) ] . obo:GO_0060084 obo:IAO_0000115 "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "synaptic transmission involved in urination" ; oboInOwl:id "GO:0060084" ; a owl:Class ; rdfs:label "synaptic transmission involved in micturition" ; rdfs:subClassOf obo:GO_0007274, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060073 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007268 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060073 ] ) ] . obo:GO_0060090 obo:IAO_0000115 "The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way." ; oboInOwl:hasAlternativeId "GO:0032947" ; oboInOwl:hasExactSynonym "binding, bridging" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "protein complex scaffold activity", "protein-containing complex scaffold activity" ; oboInOwl:id "GO:0060090" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "molecular adaptor activity" ; rdfs:subClassOf obo:GO_0003674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005488 ] . obo:GO_0060096 obo:IAO_0000115 "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "serotonin release, neurotransmission" ; oboInOwl:id "GO:0060096" ; a owl:Class ; rdfs:label "serotonin secretion, neurotransmission" ; rdfs:subClassOf obo:GO_0001820, obo:GO_0007269 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007269 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_350546 ] ) ] . obo:GO_0060097 obo:IAO_0000115 "The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060097" ; a owl:Class ; rdfs:label "cytoskeletal rearrangement involved in phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0007010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006911 ] ) ] . obo:GO_0060099 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060099" ; a owl:Class ; rdfs:label "regulation of phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0050764, obo:GO_1905153, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006911 ] ) ] . obo:GO_0060100 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060100" ; a owl:Class ; rdfs:label "positive regulation of phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0050766, obo:GO_0060099, obo:GO_1905155, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006911 ] ) ] . obo:GO_0060101 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060101" ; a owl:Class ; rdfs:label "negative regulation of phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0050765, obo:GO_0060099, obo:GO_1905154, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006911 ] ) ] . obo:GO_0060102 obo:IAO_0000115 "A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "collagen and cuticulin-based exoskeleton extracellular matrix" ; oboInOwl:id "GO:0060102" ; a owl:Class ; rdfs:label "collagen and cuticulin-based cuticle extracellular matrix" ; rdfs:subClassOf obo:GO_0062023 . obo:GO_0060106 obo:IAO_0000115 "The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0060106" ; a owl:Class ; rdfs:label "cortical layer of collagen and cuticulin-based cuticle extracellular matrix" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060102 ] . obo:GO_0060107 obo:IAO_0000115 "The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "annulae", "annular rings", "annule(s)", "annulus" ; oboInOwl:id "GO:0060107" ; a owl:Class ; rdfs:label "annuli extracellular matrix" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060106 ] . obo:GO_0060109 obo:IAO_0000115 "The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "medial layer struts" ; oboInOwl:id "GO:0060109" ; a owl:Class ; rdfs:label "medial layer of collagen and cuticulin-based cuticle extracellular matrix" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060102 ] . obo:GO_0060135 obo:IAO_0000115 "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060135" ; a owl:Class ; rdfs:label "maternal process involved in female pregnancy" ; rdfs:subClassOf obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007565 ] . obo:GO_0060136 obo:IAO_0000115 "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060136" ; a owl:Class ; rdfs:label "embryonic process involved in female pregnancy" ; rdfs:subClassOf obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007565 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009792 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022414 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007565 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ] ) ] . obo:GO_0060142 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060142" ; a owl:Class ; rdfs:label "regulation of syncytium formation by plasma membrane fusion" ; rdfs:subClassOf obo:GO_0050793, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000768 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000768 ] ) ] . obo:GO_0060143 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060143" ; a owl:Class ; rdfs:label "positive regulation of syncytium formation by plasma membrane fusion" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0051130, obo:GO_0060142, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000768 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000768 ] ) ] . obo:GO_0060157 obo:IAO_0000115 "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion." ; obo:RO_0002161 obo:NCBITaxon_8782 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060157" ; a owl:Class ; rdfs:label "urinary bladder development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_8782 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_8782 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001255 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_8782 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001255 ] ) ] . obo:GO_0060170 obo:IAO_0000115 "The portion of the plasma membrane surrounding a cilium." ; oboInOwl:hasAlternativeId "GO:0020017" ; oboInOwl:hasExactSynonym "cilial membrane", "cilium membrane" ; oboInOwl:hasNarrowSynonym "flagellar membrane", "flagellum membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0060170" ; a owl:Class ; rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent." ; rdfs:label "ciliary membrane" ; rdfs:subClassOf obo:GO_0031253, obo:GO_0098588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005929 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005929 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:GO_0060173 obo:IAO_0000115 "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin." ; oboInOwl:hasDbXref "Wikipedia:Limb_development" ; oboInOwl:hasExactSynonym "paired limb/fin development" ; oboInOwl:hasNarrowSynonym "limb bud development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060173" ; a owl:Class ; rdfs:label "limb development" ; rdfs:subClassOf obo:GO_0048736, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004708 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004708 ] ) ] . obo:GO_0060179 obo:IAO_0000115 "The specific behavior of a male organism that is associated with reproduction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060179" ; a owl:Class ; rdfs:label "male mating behavior" ; rdfs:subClassOf obo:GO_0007617 . obo:GO_0060214 obo:IAO_0000115 "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060214" ; a owl:Class ; rdfs:label "endocardium formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003160 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002165 ] ) ] . obo:GO_0060218 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ; oboInOwl:hasExactSynonym "haematopoietic stem cell differentiation", "haemopoietic stem cell differentiation", "hemopoietic stem cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060218" ; a owl:Class ; rdfs:label "hematopoietic stem cell differentiation" ; rdfs:subClassOf obo:GO_0002244, obo:GO_0048863, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000037 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000037 ] ) ] . obo:GO_0060219 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060219" ; a owl:Class ; rdfs:label "camera-type eye photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0001754, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003407 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060042 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010009 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010009 ] ) ] . obo:GO_0060221 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060221" ; a owl:Class ; rdfs:label "retinal rod cell differentiation" ; rdfs:subClassOf obo:GO_0060219, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000604 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000604 ] ) ] . obo:GO_0060231 obo:IAO_0000115 "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell." ; oboInOwl:hasExactSynonym "epithelial cell differentiation from mesenchymal cell", "mesenchymal-epithelial transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060231" ; a owl:Class ; rdfs:label "mesenchymal to epithelial transition" ; rdfs:subClassOf obo:GO_0030855, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0008019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0008019 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000066 ] ) ] . obo:GO_0060236 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." ; oboInOwl:hasExactSynonym "regulation of mitotic spindle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of mitotic spindle organization and biogenesis" ; oboInOwl:id "GO:0060236" ; a owl:Class ; rdfs:label "regulation of mitotic spindle organization" ; rdfs:subClassOf obo:GO_0090224, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007052 ] ) ] . obo:GO_0060251 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of glial cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060251" ; a owl:Class ; rdfs:label "regulation of glial cell proliferation" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014009 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014009 ] ) ] . obo:GO_0060252 obo:IAO_0000115 "Any process that activates or increases the rate or extent of glial cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060252" ; a owl:Class ; rdfs:label "positive regulation of glial cell proliferation" ; rdfs:subClassOf obo:GO_0008284, obo:GO_0014015, obo:GO_0060251, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014009 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014009 ] ) ] . obo:GO_0060253 obo:IAO_0000115 "Any process that stops or decreases the rate or extent of glial cell proliferation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060253" ; a owl:Class ; rdfs:label "negative regulation of glial cell proliferation" ; rdfs:subClassOf obo:GO_0008285, obo:GO_0014014, obo:GO_0060251, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014009 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014009 ] ) ] . obo:GO_0060255 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060255" ; a owl:Class ; rdfs:label "regulation of macromolecule metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043170 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043170 ] ) ] . obo:GO_0060259 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food." ; oboInOwl:hasExactSynonym "regulation of feeding behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060259" ; a owl:Class ; rdfs:label "regulation of feeding behavior" ; rdfs:subClassOf obo:GO_0050795, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007631 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007631 ] ) ] . obo:GO_0060271 obo:IAO_0000115 "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." ; obo:RO_0002161 obo:NCBITaxon_3176, obo:NCBITaxon_3312, obo:NCBITaxon_3378, obo:NCBITaxon_3398, obo:NCBITaxon_4890, obo:NCBITaxon_5782 ; oboInOwl:hasAlternativeId "GO:0042384" ; oboInOwl:hasDbXref "Reactome:R-HSA-5617833.2" ; oboInOwl:hasExactSynonym "ciliogenesis", "cilium formation", "microtubule-based flagellum assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cilium biogenesis", "cilium morphogenesis", "cilium organization" ; oboInOwl:id "GO:0060271" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "cilium assembly" ; rdfs:subClassOf obo:GO_0044782, obo:GO_0070925, obo:GO_0120031, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0035082 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0035735 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0061512 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0097712 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_1905349 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3176 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3312 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3378 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3398 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4890 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002224 ; owl:someValuesFrom obo:GO_0097711 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005929 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:GO_0060278 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060278" ; a owl:Class ; rdfs:label "regulation of ovulation" ; rdfs:subClassOf obo:GO_0051239, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030728 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030728 ] ) ] . obo:GO_0060279 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060279" ; a owl:Class ; rdfs:label "positive regulation of ovulation" ; rdfs:subClassOf obo:GO_0051240, obo:GO_0060278, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030728 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030728 ] ) ] . obo:GO_0060280 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060280" ; a owl:Class ; rdfs:label "negative regulation of ovulation" ; rdfs:subClassOf obo:GO_0051241, obo:GO_0060278, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030728 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030728 ] ) ] . obo:GO_0060281 obo:IAO_0000115 "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060281" ; a owl:Class ; rdfs:label "regulation of oocyte development" ; rdfs:subClassOf obo:GO_1905879, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048599 ] ) ] . obo:GO_0060282 obo:IAO_0000115 "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060282" ; a owl:Class ; rdfs:label "positive regulation of oocyte development" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0060281, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048599 ] ) ] . obo:GO_0060283 obo:IAO_0000115 "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060283" ; a owl:Class ; rdfs:label "negative regulation of oocyte development" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0060281, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048599 ] ) ] . obo:GO_0060284 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060284" ; a owl:Class ; rdfs:label "regulation of cell development" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048468 ] ) ] . obo:GO_0060285 obo:IAO_0000115 "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." ; oboInOwl:hasAlternativeId "GO:0071974" ; oboInOwl:hasExactSynonym "cilium cell motility", "microtubule-based flagellar cell motility" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ciliary cell motility" ; oboInOwl:id "GO:0060285" ; a owl:Class ; rdfs:comment "Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent." ; rdfs:label "cilium-dependent cell motility" ; rdfs:subClassOf obo:GO_0001539, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0003341 ] . obo:GO_0060293 obo:IAO_0000115 "Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line." ; oboInOwl:hasDbXref "Wikipedia:Germ_plasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0060293" ; a owl:Class ; rdfs:label "germ plasm" ; rdfs:subClassOf obo:GO_0045495 . obo:GO_0060294 obo:IAO_0000115 "Movement of cilia mediated by motor proteins that contributes to the movement of a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060294" ; a owl:Class ; rdfs:label "cilium movement involved in cell motility" ; rdfs:subClassOf obo:GO_0003341, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060285 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0003341 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048870 ] ) ] . obo:GO_0060295 obo:IAO_0000115 "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060295" ; a owl:Class ; rdfs:label "regulation of cilium movement involved in cell motility" ; rdfs:subClassOf obo:GO_0003352, obo:GO_1902019, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060294 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060294 ] ) ] . obo:GO_0060297 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ; oboInOwl:hasExactSynonym "regulation of sarcomere organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060297" ; a owl:Class ; rdfs:label "regulation of sarcomere organization" ; rdfs:subClassOf obo:GO_0110020, obo:GO_1902903, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045214 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045214 ] ) ] . obo:GO_0060298 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ; oboInOwl:hasExactSynonym "positive regulation of sarcomere organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060298" ; a owl:Class ; rdfs:label "positive regulation of sarcomere organization" ; rdfs:subClassOf obo:GO_0051155, obo:GO_0051495, obo:GO_0060297, obo:GO_1902905, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045214 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045214 ] ) ] . obo:GO_0060299 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ; oboInOwl:hasExactSynonym "negative regulation of sarcomere organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060299" ; a owl:Class ; rdfs:label "negative regulation of sarcomere organization" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0051494, obo:GO_0060297, obo:GO_1902116, obo:GO_1902904, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045214 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045214 ] ) ] . obo:GO_0060322 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060322" ; a owl:Class ; rdfs:label "head development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000033 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000033 ] ) ] . obo:GO_0060323 obo:IAO_0000115 "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060323" ; a owl:Class ; rdfs:label "head morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010171 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060322 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000033 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000033 ] ) ] . obo:GO_0060324 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060324" ; a owl:Class ; rdfs:label "face development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060322 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001456 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001456 ] ) ] . obo:GO_0060325 obo:IAO_0000115 "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060325" ; a owl:Class ; rdfs:label "face morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060323 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001456 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001456 ] ) ] . obo:GO_0060326 obo:IAO_0000115 "The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060326" ; a owl:Class ; rdfs:label "cell chemotaxis" ; rdfs:subClassOf obo:GO_0006935, obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070887 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000000 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006935 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000000 ] ) ] . obo:GO_0060341 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." ; oboInOwl:hasExactSynonym "regulation of cellular localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060341" ; a owl:Class ; rdfs:label "regulation of cellular localization" ; rdfs:subClassOf obo:GO_0032879, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051641 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051641 ] ) ] . obo:GO_0060348 obo:IAO_0000115 "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060348" ; a owl:Class ; rdfs:label "bone development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001501 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001474 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048513 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001474 ] ) ] . obo:GO_0060349 obo:IAO_0000115 "The process in which bones are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060349" ; a owl:Class ; rdfs:label "bone morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048705 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060348 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001474 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001474 ] ) ] . obo:GO_0060350 obo:IAO_0000115 "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060350" ; a owl:Class ; rdfs:label "endochondral bone morphogenesis" ; rdfs:subClassOf obo:GO_0060349, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002513 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060349 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002513 ] ) ] . obo:GO_0060351 obo:IAO_0000115 "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060351" ; a owl:Class ; rdfs:label "cartilage development involved in endochondral bone morphogenesis" ; rdfs:subClassOf obo:GO_0051216, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060350 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051216 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060350 ] ) ] . obo:GO_0060359 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." ; oboInOwl:hasAlternativeId "GO:1903717" ; oboInOwl:hasExactSynonym "response to ammonia" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060359" ; a owl:Class ; rdfs:label "response to ammonium ion" ; rdfs:subClassOf obo:GO_0010035, obo:GO_1901698, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_28938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_28938 ] ) ] . obo:GO_0060378 obo:IAO_0000115 "Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060378" ; a owl:Class ; rdfs:label "regulation of brood size" ; rdfs:subClassOf obo:GO_0044706, obo:GO_0048609, obo:GO_0065007, [ a owl:Restriction ; owl:onProperty obo:RO_0019000 ; owl:someValuesFrom obo:PATO_0000276 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0019000 ; owl:someValuesFrom obo:PATO_0000276 ] ) ] . obo:GO_0060379 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." ; oboInOwl:hasExactSynonym "myocardial precursor cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiac myoblast differentiation" ; oboInOwl:id "GO:0060379" ; a owl:Class ; rdfs:label "cardiac muscle cell myoblast differentiation" ; rdfs:subClassOf obo:GO_0010002, obo:GO_0045445, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000513 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000513 ] ) ] . obo:GO_0060404 obo:IAO_0000115 "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060404" ; a owl:Class ; rdfs:label "axonemal microtubule depolymerization" ; rdfs:subClassOf obo:GO_0010938, obo:GO_0061523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005930 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007019 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005930 ] ) ] . obo:GO_0060408 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060408" ; a owl:Class ; rdfs:label "regulation of acetylcholine metabolic process" ; rdfs:subClassOf obo:GO_0001505, obo:GO_0031323, obo:GO_0033238, obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008291 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008291 ] ) ] . obo:GO_0060409 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060409" ; a owl:Class ; rdfs:label "positive regulation of acetylcholine metabolic process" ; rdfs:subClassOf obo:GO_0031325, obo:GO_0033240, obo:GO_0060408, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008291 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008291 ] ) ] . obo:GO_0060410 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060410" ; a owl:Class ; rdfs:label "negative regulation of acetylcholine metabolic process" ; rdfs:subClassOf obo:GO_0031324, obo:GO_0033239, obo:GO_0060408, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008291 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008291 ] ) ] . obo:GO_0060411 obo:IAO_0000115 "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart." ; oboInOwl:hasAlternativeId "GO:0003280" ; oboInOwl:hasExactSynonym "heart septum morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060411" ; a owl:Class ; rdfs:label "cardiac septum morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003206 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003279 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002099 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002099 ] ) ] . obo:GO_0060412 obo:IAO_0000115 "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another." ; oboInOwl:hasExactSynonym "interventricular septum morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060412" ; a owl:Class ; rdfs:label "ventricular septum morphogenesis" ; rdfs:subClassOf obo:GO_0060411, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003281 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002094 ] ) ] . obo:GO_0060413 obo:IAO_0000115 "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another." ; oboInOwl:hasAlternativeId "GO:0003287" ; oboInOwl:hasExactSynonym "interatrial septum morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060413" ; a owl:Class ; rdfs:label "atrial septum morphogenesis" ; rdfs:subClassOf obo:GO_0060411, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003209 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003283 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002085 ] ) ] . obo:GO_0060414 obo:IAO_0000115 "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060414" ; a owl:Class ; rdfs:label "aorta smooth muscle tissue morphogenesis" ; rdfs:subClassOf obo:GO_0060415, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035909 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048745 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004178 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004178 ] ) ] . obo:GO_0060415 obo:IAO_0000115 "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060415" ; a owl:Class ; rdfs:label "muscle tissue morphogenesis" ; rdfs:subClassOf obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048644 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002385 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048729 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002385 ] ) ] . obo:GO_0060419 obo:IAO_0000115 "The increase in size or mass of the heart." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060419" ; a owl:Class ; rdfs:label "heart growth" ; rdfs:subClassOf obo:GO_0035265, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000948 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0000948 ] ) ] . obo:GO_0060420 obo:IAO_0000115 "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060420" ; a owl:Class ; rdfs:label "regulation of heart growth" ; rdfs:subClassOf obo:GO_0046620, obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060419 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060419 ] ) ] . obo:GO_0060421 obo:IAO_0000115 "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060421" ; a owl:Class ; rdfs:label "positive regulation of heart growth" ; rdfs:subClassOf obo:GO_0046622, obo:GO_0060420, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060419 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060419 ] ) ] . obo:GO_0060425 obo:IAO_0000115 "The process in which the anatomical structures of the lung are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060425" ; a owl:Class ; rdfs:label "lung morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:GO_0060426 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs." ; oboInOwl:hasExactSynonym "pulmonary vasculature development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060426" ; a owl:Class ; rdfs:label "lung vasculature development" ; rdfs:subClassOf obo:GO_0001944, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000102 ] ) ] . obo:GO_0060427 obo:IAO_0000115 "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs." ; oboInOwl:hasExactSynonym "pulmonary connective tissue development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060427" ; a owl:Class ; rdfs:label "lung connective tissue development" ; rdfs:subClassOf obo:GO_0061448, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000114 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000114 ] ) ] . obo:GO_0060428 obo:IAO_0000115 "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung." ; oboInOwl:hasExactSynonym "pulmonary epithelium development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060428" ; a owl:Class ; rdfs:label "lung epithelium development" ; rdfs:subClassOf obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000115 ] ) ] . obo:GO_0060429 obo:IAO_0000115 "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060429" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "epithelium development" ; rdfs:subClassOf obo:GO_0009888, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000483 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000483 ] ) ] . obo:GO_0060431 obo:IAO_0000115 "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds." ; oboInOwl:hasExactSynonym "lung formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060431" ; a owl:Class ; rdfs:label "primary lung bud formation" ; rdfs:subClassOf obo:GO_0016331, obo:GO_0048645, obo:GO_0060441, obo:GO_0060572, [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:GO_0060433 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060433" ; a owl:Class ; rdfs:label "bronchus development" ; rdfs:subClassOf obo:GO_0030323, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060541 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002185 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002185 ] ) ] . obo:GO_0060434 obo:IAO_0000115 "The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060434" ; a owl:Class ; rdfs:label "bronchus morphogenesis" ; rdfs:subClassOf obo:GO_0009887, obo:GO_0035239, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060433 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002185 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002185 ] ) ] . obo:GO_0060435 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060435" ; a owl:Class ; rdfs:label "bronchiole development" ; rdfs:subClassOf obo:GO_0030323, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002186 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002186 ] ) ] . obo:GO_0060436 obo:IAO_0000115 "The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060436" ; a owl:Class ; rdfs:label "bronchiole morphogenesis" ; rdfs:subClassOf obo:GO_0035239, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060435 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002186 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002186 ] ) ] . obo:GO_0060437 obo:IAO_0000115 "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060437" ; a owl:Class ; rdfs:label "lung growth" ; rdfs:subClassOf obo:GO_0035265, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:GO_0060438 obo:IAO_0000115 "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060438" ; a owl:Class ; rdfs:label "trachea development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060541 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001005 ] ) ] . obo:GO_0060439 obo:IAO_0000115 "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060439" ; a owl:Class ; rdfs:label "trachea morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060438 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001005 ] ) ] . obo:GO_0060440 obo:IAO_0000115 "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060440" ; a owl:Class ; rdfs:label "trachea formation" ; rdfs:subClassOf obo:GO_0048645, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060439 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001005 ] ) ] . obo:GO_0060441 obo:IAO_0000115 "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." ; oboInOwl:hasExactSynonym "lung branching morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060441" ; a owl:Class ; rdfs:label "epithelial tube branching involved in lung morphogenesis" ; rdfs:subClassOf obo:GO_0048754, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060425 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048754 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060425 ] ) ] . obo:GO_0060450 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060450" ; a owl:Class ; rdfs:label "positive regulation of hindgut contraction" ; rdfs:subClassOf obo:GO_0043134, obo:GO_0045987, obo:GO_0060456, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043133 ] ) ] . obo:GO_0060451 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060451" ; a owl:Class ; rdfs:label "negative regulation of hindgut contraction" ; rdfs:subClassOf obo:GO_0043134, obo:GO_0045986, obo:GO_0060457, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043133 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043133 ] ) ] . obo:GO_0060452 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of cardiac muscle contraction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060452" ; a owl:Class ; rdfs:label "positive regulation of cardiac muscle contraction" ; rdfs:subClassOf obo:GO_0045823, obo:GO_0045989, obo:GO_0055117, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060048 ] ) ] . obo:GO_0060453 obo:IAO_0000115 "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060453" ; a owl:Class ; rdfs:label "regulation of gastric acid secretion" ; rdfs:subClassOf obo:GO_0044058, obo:GO_0051046, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001696 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001696 ] ) ] . obo:GO_0060454 obo:IAO_0000115 "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060454" ; a owl:Class ; rdfs:label "positive regulation of gastric acid secretion" ; rdfs:subClassOf obo:GO_0051047, obo:GO_0060453, obo:GO_0060456, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001696 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001696 ] ) ] . obo:GO_0060455 obo:IAO_0000115 "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060455" ; a owl:Class ; rdfs:label "negative regulation of gastric acid secretion" ; rdfs:subClassOf obo:GO_0051048, obo:GO_0060453, obo:GO_0060457, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001696 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001696 ] ) ] . obo:GO_0060456 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060456" ; a owl:Class ; rdfs:label "positive regulation of digestive system process" ; rdfs:subClassOf obo:GO_0044058, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022600 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022600 ] ) ] . obo:GO_0060457 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060457" ; a owl:Class ; rdfs:label "negative regulation of digestive system process" ; rdfs:subClassOf obo:GO_0044058, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022600 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022600 ] ) ] . obo:GO_0060458 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect." ; oboInOwl:hasExactSynonym "right pulmonary development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060458" ; a owl:Class ; rdfs:label "right lung development" ; rdfs:subClassOf obo:GO_0030324, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002167 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002167 ] ) ] . obo:GO_0060459 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect." ; oboInOwl:hasExactSynonym "left pulmonary development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060459" ; a owl:Class ; rdfs:label "left lung development" ; rdfs:subClassOf obo:GO_0030324, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002168 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002168 ] ) ] . obo:GO_0060460 obo:IAO_0000115 "The process in which anatomical structures of the left lung are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060460" ; a owl:Class ; rdfs:label "left lung morphogenesis" ; rdfs:subClassOf obo:GO_0060425, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060459 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002168 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002168 ] ) ] . obo:GO_0060461 obo:IAO_0000115 "The process in which anatomical structures of the right lung are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060461" ; a owl:Class ; rdfs:label "right lung morphogenesis" ; rdfs:subClassOf obo:GO_0060425, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060458 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002167 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002167 ] ) ] . obo:GO_0060465 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pharyngeal development" ; oboInOwl:id "GO:0060465" ; a owl:Class ; rdfs:label "pharynx development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048565 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006562 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006562 ] ) ] . obo:GO_0060467 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060467" ; a owl:Class ; rdfs:label "negative regulation of fertilization" ; rdfs:subClassOf obo:GO_0080154, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009566 ] ) ] . obo:GO_0060468 obo:IAO_0000115 "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg." ; oboInOwl:hasExactSynonym "negative regulation of fertilization involved in egg activation", "polyspermy block" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060468" ; a owl:Class ; rdfs:label "prevention of polyspermy" ; rdfs:subClassOf obo:GO_0022414, obo:GO_0060467, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007343 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060467 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007343 ] ) ] . obo:GO_0060474 obo:IAO_0000115 "The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of sperm motility involved in capacitation" ; oboInOwl:id "GO:0060474" ; a owl:Class ; rdfs:label "positive regulation of flagellated sperm motility involved in capacitation" ; rdfs:subClassOf obo:GO_0022414, obo:GO_1902093, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048240 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_1902093 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048240 ] ) ] . obo:GO_0060479 obo:IAO_0000115 "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate." ; oboInOwl:hasExactSynonym "pulmonary cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060479" ; a owl:Class ; rdfs:label "lung cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ] . obo:GO_0060485 obo:IAO_0000115 "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells." ; oboInOwl:hasExactSynonym "mesenchymal development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060485" ; a owl:Class ; rdfs:label "mesenchyme development" ; rdfs:subClassOf obo:GO_0009888, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048513 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003104 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003104 ] ) ] . obo:GO_0060486 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles." ; oboInOwl:hasExactSynonym "Clara cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060486" ; a owl:Class ; rdfs:label "club cell differentiation" ; rdfs:subClassOf obo:GO_0060487, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000158 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000158 ] ) ] . obo:GO_0060487 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pulmonary epithelial cell differentiation" ; oboInOwl:id "GO:0060487" ; a owl:Class ; rdfs:label "lung epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0030855, obo:GO_0060479, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060428 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000082 ] ) ] . obo:GO_0060491 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of cell projection assembly." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cell projection formation" ; oboInOwl:id "GO:0060491" ; a owl:Class ; rdfs:label "regulation of cell projection assembly" ; rdfs:subClassOf obo:GO_0031344, obo:GO_0044087, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030031 ] ) ] . obo:GO_0060495 obo:IAO_0000115 "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure." ; oboInOwl:hasExactSynonym "cell-cell signalling involved in lung development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060495" ; a owl:Class ; rdfs:label "cell-cell signaling involved in lung development" ; rdfs:subClassOf obo:GO_0007267, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ] ) ] . obo:GO_0060501 obo:IAO_0000115 "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060501" ; a owl:Class ; rdfs:label "positive regulation of epithelial cell proliferation involved in lung morphogenesis" ; rdfs:subClassOf obo:GO_0050679, obo:GO_2000794, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060502 ] ) ] . obo:GO_0060502 obo:IAO_0000115 "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060502" ; a owl:Class ; rdfs:label "epithelial cell proliferation involved in lung morphogenesis" ; rdfs:subClassOf obo:GO_0050673, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060425 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060428 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050673 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060425 ] ) ] . obo:GO_0060532 obo:IAO_0000115 "The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T08:12:06Z" ; oboInOwl:hasExactSynonym "pulmonary cartilage development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060532" ; a owl:Class ; rdfs:label "bronchus cartilage development" ; rdfs:subClassOf obo:GO_0051216, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060433 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001956 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001956 ] ) ] . obo:GO_0060533 obo:IAO_0000115 "The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T08:47:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060533" ; a owl:Class ; rdfs:label "bronchus cartilage morphogenesis" ; rdfs:subClassOf obo:GO_0060536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060434 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060532 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001956 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001956 ] ) ] . obo:GO_0060534 obo:IAO_0000115 "The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T09:00:18Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060534" ; a owl:Class ; rdfs:label "trachea cartilage development" ; rdfs:subClassOf obo:GO_0051216, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060438 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003604 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003604 ] ) ] . obo:GO_0060535 obo:IAO_0000115 "The process in which the anatomical structures of cartilage in the trachea are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T09:07:48Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060535" ; a owl:Class ; rdfs:label "trachea cartilage morphogenesis" ; rdfs:subClassOf obo:GO_0060536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060439 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060534 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003604 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003604 ] ) ] . obo:GO_0060536 obo:IAO_0000115 "The process in which the anatomical structures of cartilage are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T09:13:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060536" ; a owl:Class ; rdfs:label "cartilage morphogenesis" ; rdfs:subClassOf obo:GO_0009887, obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051216 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007844 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007844 ] ) ] . obo:GO_0060537 obo:IAO_0000115 "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T08:05:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060537" ; a owl:Class ; rdfs:label "muscle tissue development" ; rdfs:subClassOf obo:GO_0009888, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002385 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002385 ] ) ] . obo:GO_0060538 obo:IAO_0000115 "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T08:25:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060538" ; a owl:Class ; rdfs:label "skeletal muscle organ development" ; rdfs:subClassOf obo:GO_0007517, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0014892 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0014892 ] ) ] . obo:GO_0060539 obo:IAO_0000115 "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs." ; obo:RO_0002161 obo:NCBITaxon_8782 ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T08:44:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060539" ; a owl:Class ; rdfs:label "diaphragm development" ; rdfs:subClassOf obo:GO_0060538, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_8782 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060541 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_8782 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001103 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_8782 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001103 ] ) ] . obo:GO_0060540 obo:IAO_0000115 "The process in which the anatomical structures of the diaphragm are generated and organized." ; obo:RO_0002161 obo:NCBITaxon_8782 ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T08:47:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060540" ; a owl:Class ; rdfs:label "diaphragm morphogenesis" ; rdfs:subClassOf obo:GO_0048644, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_8782 ] ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060539 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_8782 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001103 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_8782 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001103 ] ) ] . obo:GO_0060541 obo:IAO_0000115 "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T08:55:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060541" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "respiratory system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001004 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001004 ] ) ] . obo:GO_0060548 obo:IAO_0000115 "Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-13T01:56:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060548" ; a owl:Class ; rdfs:label "negative regulation of cell death" ; rdfs:subClassOf obo:GO_0010941, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008219 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008219 ] ) ] . obo:GO_0060560 obo:IAO_0000115 "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-28T08:42:53Z" ; oboInOwl:hasExactSynonym "differential growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060560" ; a owl:Class ; rdfs:label "developmental growth involved in morphogenesis" ; rdfs:subClassOf obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ) ] . obo:GO_0060561 obo:IAO_0000115 "Any apoptotic process that contributes to the shaping of an anatomical structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-28T09:17:27Z" ; oboInOwl:hasNarrowSynonym "apoptosis involved in morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "apoptosis involved in development", "morphogenetic apoptosis" ; oboInOwl:id "GO:0060561" ; a owl:Class ; rdfs:label "apoptotic process involved in morphogenesis" ; rdfs:subClassOf obo:GO_1902742, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ) ] . obo:GO_0060562 obo:IAO_0000115 "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-28T09:33:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060562" ; a owl:Class ; rdfs:label "epithelial tube morphogenesis" ; rdfs:subClassOf obo:GO_0002009, obo:GO_0035239, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003914 ] ) ] . obo:GO_0060563 obo:IAO_0000115 "The process in which epiblast cells acquire specialized features of neuroepithelial cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-29T01:50:05Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060563" ; a owl:Class ; rdfs:label "neuroepithelial cell differentiation" ; rdfs:subClassOf obo:GO_0002065, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000710 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000710 ] ) ] . obo:GO_0060571 obo:IAO_0000115 "The morphogenetic process in which an epithelial sheet bends along a linear axis." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-30T09:27:17Z" ; oboInOwl:hasExactSynonym "epithelial folding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "folding of an epithelial sheet" ; oboInOwl:id "GO:0060571" ; a owl:Class ; rdfs:label "morphogenesis of an epithelial fold" ; rdfs:subClassOf obo:GO_0002009, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005157 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005157 ] ) ] . obo:GO_0060572 obo:IAO_0000115 "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-30T09:38:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060572" ; a owl:Class ; rdfs:label "morphogenesis of an epithelial bud" ; rdfs:subClassOf obo:GO_0060571, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005153 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005153 ] ) ] . obo:GO_0060574 obo:IAO_0000115 "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-06T08:10:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060574" ; a owl:Class ; rdfs:label "intestinal epithelial cell maturation" ; rdfs:subClassOf obo:GO_0002069, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060576 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0002563 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0002563 ] ) ] . obo:GO_0060575 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-06T08:17:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060575" ; a owl:Class ; rdfs:label "intestinal epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0002065, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048565 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002563 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002563 ] ) ] . obo:GO_0060576 obo:IAO_0000115 "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-06T08:20:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060576" ; a owl:Class ; rdfs:label "intestinal epithelial cell development" ; rdfs:subClassOf obo:GO_0002066, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060575 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002563 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002563 ] ) ] . obo:GO_0060577 obo:IAO_0000115 "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-06T08:44:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pulmonary venous blood vessel morphogenesis" ; oboInOwl:id "GO:0060577" ; a owl:Class ; rdfs:label "pulmonary vein morphogenesis" ; rdfs:subClassOf obo:GO_0048845, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002016 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002016 ] ) ] . obo:GO_0060578 obo:IAO_0000115 "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-06T08:47:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060578" ; a owl:Class ; rdfs:label "superior vena cava morphogenesis" ; rdfs:subClassOf obo:GO_0048845, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001585 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001585 ] ) ] . obo:GO_0060581 obo:IAO_0000115 "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-07T12:40:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060581" ; a owl:Class ; rdfs:label "cell fate commitment involved in pattern specification" ; rdfs:subClassOf obo:GO_0045165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007389 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045165 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007389 ] ) ] . obo:GO_0060591 obo:IAO_0000115 "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-11T07:47:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chondrocyte progenitor cell differentiation" ; oboInOwl:id "GO:0060591" ; a owl:Class ; rdfs:label "chondroblast differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051216 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000058 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000058 ] ) ] . obo:GO_0060612 obo:IAO_0000115 "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-15T12:36:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "adipogenesis" ; oboInOwl:id "GO:0060612" ; a owl:Class ; rdfs:label "adipose tissue development" ; rdfs:subClassOf obo:GO_0061448, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048513 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001013 ] ) ] . obo:GO_0060623 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T02:12:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060623" ; a owl:Class ; rdfs:label "regulation of chromosome condensation" ; rdfs:subClassOf obo:GO_0033044, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030261 ] ) ] . obo:GO_0060627 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T02:29:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060627" ; a owl:Class ; rdfs:label "regulation of vesicle-mediated transport" ; rdfs:subClassOf obo:GO_0050794, obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016192 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016192 ] ) ] . obo:GO_0060629 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T02:41:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060629" ; a owl:Class ; rdfs:label "regulation of homologous chromosome segregation" ; rdfs:subClassOf obo:GO_0051983, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045143 ] ) ] . obo:GO_0060631 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T02:55:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060631" ; a owl:Class ; rdfs:label "regulation of meiosis I" ; rdfs:subClassOf obo:GO_0040020, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0060632 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T03:07:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060632" ; a owl:Class ; rdfs:label "regulation of microtubule-based movement" ; rdfs:subClassOf obo:GO_0032886, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007018 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007018 ] ) ] . obo:GO_0060669 obo:IAO_0000115 "The process in which the embryonic placenta is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-02T09:33:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060669" ; a owl:Class ; rdfs:label "embryonic placenta morphogenesis" ; rdfs:subClassOf obo:GO_0048598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001892 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007106 ] ) ] . obo:GO_0060670 obo:IAO_0000115 "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-02T10:40:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060670" ; a owl:Class ; rdfs:label "branching involved in labyrinthine layer morphogenesis" ; rdfs:subClassOf obo:GO_0048598, obo:GO_0061138, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060713 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061138 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060713 ] ) ] . obo:GO_0060671 obo:IAO_0000115 "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-02T11:40:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060671" ; a owl:Class ; rdfs:label "epithelial cell differentiation involved in embryonic placenta development" ; rdfs:subClassOf obo:GO_0030855, obo:GO_0060706, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060711 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030855 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001892 ] ) ] . obo:GO_0060673 obo:IAO_0000115 "Any process that mediates the transfer of information from one cell to another." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-02T12:58:03Z" ; oboInOwl:hasExactSynonym "cell-cell signalling involved in placenta development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060673" ; a owl:Class ; rdfs:label "cell-cell signaling involved in placenta development" ; rdfs:subClassOf obo:GO_0007267, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001892 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001890 ] ) ] . obo:GO_0060674 obo:IAO_0000115 "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-02T01:09:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060674" ; a owl:Class ; rdfs:label "placenta blood vessel development" ; rdfs:subClassOf obo:GO_0001568, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001890 ] . obo:GO_0060675 obo:IAO_0000115 "The process in which the ureteric bud is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-02T01:31:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060675" ; a owl:Class ; rdfs:label "ureteric bud morphogenesis" ; rdfs:subClassOf obo:GO_0072171, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001657 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000084 ] ) ] . obo:GO_0060676 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-02T01:47:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060676" ; a owl:Class ; rdfs:label "ureteric bud formation" ; rdfs:subClassOf obo:GO_0072172, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060675 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000084 ] ) ] . obo:GO_0060688 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-05T12:41:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060688" ; a owl:Class ; rdfs:label "regulation of morphogenesis of a branching structure" ; rdfs:subClassOf obo:GO_0022603, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001763 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001763 ] ) ] . obo:GO_0060706 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-09T10:26:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060706" ; a owl:Class ; rdfs:label "cell differentiation involved in embryonic placenta development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001892 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001892 ] ) ] . obo:GO_0060711 obo:IAO_0000115 "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-09T03:27:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060711" ; a owl:Class ; rdfs:label "labyrinthine layer development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001892 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003946 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003946 ] ) ] . obo:GO_0060713 obo:IAO_0000115 "The process in which the labyrinthine layer of the placenta is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-10T08:10:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060713" ; a owl:Class ; rdfs:label "labyrinthine layer morphogenesis" ; rdfs:subClassOf obo:GO_0048598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060669 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060711 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003946 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003946 ] ) ] . obo:GO_0060714 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-10T08:13:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060714" ; a owl:Class ; rdfs:label "labyrinthine layer formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060713 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003946 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003946 ] ) ] . obo:GO_0060716 obo:IAO_0000115 "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-11T09:04:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060716" ; a owl:Class ; rdfs:label "labyrinthine layer blood vessel development" ; rdfs:subClassOf obo:GO_0048568, obo:GO_0060674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060711 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004183 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004183 ] ) ] . obo:GO_0060717 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-11T02:37:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060717" ; a owl:Class ; rdfs:label "chorion development" ; rdfs:subClassOf obo:GO_1903867, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003124 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003124 ] ) ] . obo:GO_0060718 obo:IAO_0000115 "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-11T02:48:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060718" ; a owl:Class ; rdfs:label "chorionic trophoblast cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060717 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0011101 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0011101 ] ) ] . obo:GO_0060719 obo:IAO_0000115 "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-11T02:58:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060719" ; a owl:Class ; rdfs:label "chorionic trophoblast cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060718 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0011101 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0011101 ] ) ] . obo:GO_0060722 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-12T12:46:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060722" ; a owl:Class ; rdfs:label "cell proliferation involved in embryonic placenta development" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001892 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001892 ] ) ] . obo:GO_0060723 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-12T12:50:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060723" ; a owl:Class ; rdfs:label "regulation of cell proliferation involved in embryonic placenta development" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060722 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060722 ] ) ] . obo:GO_0060756 obo:IAO_0000115 "Behavior by which an organism locates food." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-22T02:46:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060756" ; a owl:Class ; rdfs:label "foraging behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0060788 obo:IAO_0000115 "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-04T12:15:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060788" ; a owl:Class ; rdfs:label "ectodermal placode formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071697 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005085 ] ) ] . obo:GO_0060795 obo:IAO_0000115 "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-04T03:11:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060795" ; a owl:Class ; rdfs:label "cell fate commitment involved in formation of primary germ layer" ; rdfs:subClassOf obo:GO_0045165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001704 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045165 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001704 ] ) ] . obo:GO_0060800 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-06T01:20:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060800" ; a owl:Class ; rdfs:label "regulation of cell differentiation involved in embryonic placenta development" ; rdfs:subClassOf obo:GO_0045595, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060706 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060706 ] ) ] . obo:GO_0060806 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-06T02:02:18Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060806" ; a owl:Class ; rdfs:label "negative regulation of cell differentiation involved in embryonic placenta development" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0060800, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060706 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060706 ] ) ] . obo:GO_0060815 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-07T10:02:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060815" ; a owl:Class ; rdfs:label "regulation of translation involved in anterior/posterior axis specification" ; rdfs:subClassOf obo:GO_0006417, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009948 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006417 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009948 ] ) ] . obo:GO_0060837 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-11T03:47:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060837" ; a owl:Class ; rdfs:label "blood vessel endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0045446, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001568 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000071 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000071 ] ) ] . obo:GO_0060840 obo:IAO_0000115 "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-12T10:10:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060840" ; a owl:Class ; rdfs:label "artery development" ; rdfs:subClassOf obo:GO_0001568, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001637 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001637 ] ) ] . obo:GO_0060841 obo:IAO_0000115 "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-12T10:14:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060841" ; a owl:Class ; rdfs:label "venous blood vessel development" ; rdfs:subClassOf obo:GO_0001568, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001638 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001638 ] ) ] . obo:GO_0060842 obo:IAO_0000115 "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-12T10:41:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060842" ; a owl:Class ; rdfs:label "arterial endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0060837, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000413 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000413 ] ) ] . obo:GO_0060843 obo:IAO_0000115 "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-12T10:43:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060843" ; a owl:Class ; rdfs:label "venous endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0060837, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002543 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002543 ] ) ] . obo:GO_0060896 obo:IAO_0000115 "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-13T02:06:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060896" ; a owl:Class ; rdfs:label "neural plate pattern specification" ; rdfs:subClassOf obo:GO_0007389 . obo:GO_0060897 obo:IAO_0000115 "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-13T02:09:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060897" ; a owl:Class ; rdfs:label "neural plate regionalization" ; rdfs:subClassOf obo:GO_0003002, obo:GO_0060896 . obo:GO_0060900 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-13T02:26:54Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060900" ; a owl:Class ; rdfs:label "embryonic camera-type eye formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048596 ] . obo:GO_0060903 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-14T01:06:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060903" ; a owl:Class ; rdfs:label "positive regulation of meiosis I" ; rdfs:subClassOf obo:GO_0045836, obo:GO_0060631, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0060914 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-17T09:02:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiogenesis" ; oboInOwl:id "GO:0060914" ; a owl:Class ; rdfs:label "heart formation" ; rdfs:subClassOf obo:GO_0048645, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000948 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000948 ] ) ] . obo:GO_0060915 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-18T11:45:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060915" ; a owl:Class ; rdfs:label "mesenchymal cell differentiation involved in lung development" ; rdfs:subClassOf obo:GO_0048762, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048762 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ] ) ] . obo:GO_0060916 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-18T11:50:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060916" ; a owl:Class ; rdfs:label "mesenchymal cell proliferation involved in lung development" ; rdfs:subClassOf obo:GO_0010463, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0010463 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030324 ] ) ] . obo:GO_0060920 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T11:01:31Z" ; oboInOwl:hasBroadSynonym "pacemaker cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060920" ; a owl:Class ; rdfs:label "cardiac pacemaker cell differentiation" ; rdfs:subClassOf obo:GO_0055007, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002072 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002072 ] ) ] . obo:GO_0060921 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T11:03:30Z" ; oboInOwl:hasExactSynonym "SA node cell differentiation", "SAN cell differentiation" ; oboInOwl:hasNarrowSynonym "sinus node cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060921" ; a owl:Class ; rdfs:label "sinoatrial node cell differentiation" ; rdfs:subClassOf obo:GO_0060920, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003163 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000409 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000409 ] ) ] . obo:GO_0060922 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T11:07:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "AV node cell differentiation" ; oboInOwl:id "GO:0060922" ; a owl:Class ; rdfs:label "atrioventricular node cell differentiation" ; rdfs:subClassOf obo:GO_0003292, obo:GO_0060920, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003162 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000410 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000410 ] ) ] . obo:GO_0060926 obo:IAO_0000115 "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T11:51:55Z" ; oboInOwl:hasBroadSynonym "pacemaker cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060926" ; a owl:Class ; rdfs:label "cardiac pacemaker cell development" ; rdfs:subClassOf obo:GO_0055013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060920 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002072 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002072 ] ) ] . obo:GO_0060928 obo:IAO_0000115 "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T11:59:26Z" ; oboInOwl:hasExactSynonym "AV node cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060928" ; a owl:Class ; rdfs:label "atrioventricular node cell development" ; rdfs:subClassOf obo:GO_0060926, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060922 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_1000410 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_1000410 ] ) ] . obo:GO_0060931 obo:IAO_0000115 "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T12:05:47Z" ; oboInOwl:hasExactSynonym "SA node cell development", "SAN cell development" ; oboInOwl:hasNarrowSynonym "sinus node cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060931" ; a owl:Class ; rdfs:label "sinoatrial node cell development" ; rdfs:subClassOf obo:GO_0060926, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060921 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_1000409 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_1000409 ] ) ] . obo:GO_0060932 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T01:10:32Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060932" ; a owl:Class ; rdfs:label "His-Purkinje system cell differentiation" ; rdfs:subClassOf obo:GO_0055007, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003164 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010007 ] ) ] . obo:GO_0060933 obo:IAO_0000115 "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T01:15:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060933" ; a owl:Class ; rdfs:label "His-Purkinje system cell development" ; rdfs:subClassOf obo:GO_0055006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060932 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0010007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0010007 ] ) ] . obo:GO_0060935 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T01:20:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060935" ; a owl:Class ; rdfs:label "cardiac fibroblast cell differentiation" ; rdfs:subClassOf obo:GO_0035051, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002548 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002548 ] ) ] . obo:GO_0060936 obo:IAO_0000115 "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T01:23:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060936" ; a owl:Class ; rdfs:label "cardiac fibroblast cell development" ; rdfs:subClassOf obo:GO_0055006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060935 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002548 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002548 ] ) ] . obo:GO_0060945 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T02:45:33Z" ; oboInOwl:hasExactSynonym "heart neuron differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060945" ; a owl:Class ; rdfs:label "cardiac neuron differentiation" ; rdfs:subClassOf obo:GO_0030182, obo:GO_0035051, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048483 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010022 ] ) ] . obo:GO_0060946 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T02:48:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060946" ; a owl:Class ; rdfs:label "cardiac blood vessel endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0003348, obo:GO_0060837, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010006 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010006 ] ) ] . obo:GO_0060950 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T03:06:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060950" ; a owl:Class ; rdfs:label "cardiac glial cell differentiation" ; rdfs:subClassOf obo:GO_0010001, obo:GO_0035051, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0010020 ] ) ] . obo:GO_0060952 obo:IAO_0000115 "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T03:09:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060952" ; a owl:Class ; rdfs:label "cardiac glial cell development" ; rdfs:subClassOf obo:GO_0021782, obo:GO_0055006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060950 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0010020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0010020 ] ) ] . obo:GO_0060956 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T03:20:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060956" ; a owl:Class ; rdfs:label "endocardial cell differentiation" ; rdfs:subClassOf obo:GO_0003348, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003157 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002350 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002350 ] ) ] . obo:GO_0060958 obo:IAO_0000115 "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-29T03:26:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060958" ; a owl:Class ; rdfs:label "endocardial cell development" ; rdfs:subClassOf obo:GO_0001885, obo:GO_0055006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060956 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002350 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0002350 ] ) ] . obo:GO_0060959 obo:IAO_0000115 "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-09-30T10:14:56Z" ; oboInOwl:hasExactSynonym "heart neuron development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060959" ; a owl:Class ; rdfs:label "cardiac neuron development" ; rdfs:subClassOf obo:GO_0048666, obo:GO_0055006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060945 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0010022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0010022 ] ) ] . obo:GO_0060973 obo:IAO_0000115 "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-06T10:53:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060973" ; a owl:Class ; rdfs:label "cell migration involved in heart development" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ] ) ] . obo:GO_0060974 obo:IAO_0000115 "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-06T10:56:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060974" ; a owl:Class ; rdfs:label "cell migration involved in heart formation" ; rdfs:subClassOf obo:GO_0060973, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060914 ] ) ] . obo:GO_0060976 obo:IAO_0000115 "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-06T12:15:23Z" ; oboInOwl:hasExactSynonym "cardiac blood vessel development", "cardiac vasculature development", "coronary blood vessel development", "heart blood vessel development", "heart vasculature development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060976" ; a owl:Class ; rdfs:label "coronary vasculature development" ; rdfs:subClassOf obo:GO_0001568, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003498 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003498 ] ) ] . obo:GO_0060977 obo:IAO_0000115 "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-06T12:28:23Z" ; oboInOwl:hasExactSynonym "cardiac blood vessel morphogenesis", "cardiac vasculature morphogenesis", "coronary blood vessel morphogenesis", "heart blood vessel morphogenesis", "heart vasculature morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060977" ; a owl:Class ; rdfs:label "coronary vasculature morphogenesis" ; rdfs:subClassOf obo:GO_0048514, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060976 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003498 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003498 ] ) ] . obo:GO_0060978 obo:IAO_0000115 "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-06T02:02:12Z" ; oboInOwl:hasExactSynonym "angiogenesis involved in cardiac vascular morphogenesis", "angiogenesis involved in heart vascular morphogenesis", "coronary blood vessel angiogenesis", "coronary vasculature angiogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060978" ; a owl:Class ; rdfs:label "angiogenesis involved in coronary vascular morphogenesis" ; rdfs:subClassOf obo:GO_0001525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060977 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001525 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060976 ] ) ] . obo:GO_0060979 obo:IAO_0000115 "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-06T02:19:42Z" ; oboInOwl:hasExactSynonym "coronary vasculogenesis", "vasculogenesis involved in coronary blood vessel morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060979" ; a owl:Class ; rdfs:label "vasculogenesis involved in coronary vascular morphogenesis" ; rdfs:subClassOf obo:GO_0001570, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060977 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001570 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060977 ] ) ] . obo:GO_0060980 obo:IAO_0000115 "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-06T02:33:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060980" ; a owl:Class ; rdfs:label "cell migration involved in coronary vasculogenesis" ; rdfs:subClassOf obo:GO_0035441, obo:GO_0060973, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060979 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060979 ] ) ] . obo:GO_0060981 obo:IAO_0000115 "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-10-06T02:49:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060981" ; a owl:Class ; rdfs:label "cell migration involved in coronary angiogenesis" ; rdfs:subClassOf obo:GO_0060973, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060978 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060978 ] ) ] . obo:GO_0060986 obo:IAO_0000115 "The regulated release of a hormone into the circulatory system." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-11T09:03:48Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060986" ; a owl:Class ; rdfs:label "endocrine hormone secretion" ; rdfs:subClassOf obo:GO_0046879, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050886 ] . obo:GO_0060993 obo:IAO_0000115 "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-19T08:16:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060993" ; a owl:Class ; rdfs:label "kidney morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002113 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002113 ] ) ] . obo:GO_0060995 obo:IAO_0000115 "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-19T08:33:40Z" ; oboInOwl:hasExactSynonym "cell-cell signalling involved in kidney development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060995" ; a owl:Class ; rdfs:label "cell-cell signaling involved in kidney development" ; rdfs:subClassOf obo:GO_0007267, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0061004 obo:IAO_0000115 "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-21T09:05:54Z" ; oboInOwl:hasExactSynonym "kidney pattern specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "kidney pattern formation", "pattern formation involved in kidney development" ; oboInOwl:id "GO:0061004" ; a owl:Class ; rdfs:label "pattern specification involved in kidney development" ; rdfs:subClassOf obo:GO_0007389, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007389 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0061005 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-21T09:13:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061005" ; a owl:Class ; rdfs:label "cell differentiation involved in kidney development" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0061006 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-21T11:25:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061006" ; a owl:Class ; rdfs:label "regulation of cell proliferation involved in kidney morphogenesis" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060993 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042127 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060993 ] ) ] . obo:GO_0061007 obo:IAO_0000115 "An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-22T09:09:10Z" ; oboInOwl:hasExactSynonym "hepatobiliary system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061007" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "hepaticobiliary system process" ; rdfs:subClassOf obo:GO_0003008 . obo:GO_0061008 obo:IAO_0000115 "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-22T09:11:59Z" ; oboInOwl:hasExactSynonym "hepatobiliary system development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061008" ; a owl:Class ; rdfs:label "hepaticobiliary system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002423 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002423 ] ) ] . obo:GO_0061009 obo:IAO_0000115 "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-22T09:17:13Z" ; oboInOwl:hasBroadSynonym "EHBD development", "extrahepatic bile duct development" ; oboInOwl:hasExactSynonym "CBD development", "bile duct development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061009" ; a owl:Class ; rdfs:label "common bile duct development" ; rdfs:subClassOf obo:GO_0035295, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061008 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002394 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002394 ] ) ] . obo:GO_0061010 obo:IAO_0000115 "The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-22T09:38:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061010" ; a owl:Class ; rdfs:label "gallbladder development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061008 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002110 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002110 ] ) ] . obo:GO_0061011 obo:IAO_0000115 "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-22T09:44:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061011" ; a owl:Class ; rdfs:label "hepatic duct development" ; rdfs:subClassOf obo:GO_0061009, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001175 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001175 ] ) ] . obo:GO_0061013 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-29T01:48:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of mRNA decay" ; oboInOwl:id "GO:0061013" ; a owl:Class ; rdfs:label "regulation of mRNA catabolic process" ; rdfs:subClassOf obo:GO_0010468, obo:GO_0031329, obo:GO_1903311, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006402 ] ) ] . obo:GO_0061014 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-29T01:58:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of mRNA decay" ; oboInOwl:id "GO:0061014" ; a owl:Class ; rdfs:label "positive regulation of mRNA catabolic process" ; rdfs:subClassOf obo:GO_0031331, obo:GO_0061013, obo:GO_1903313, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006402 ] ) ] . obo:GO_0061017 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-02T09:08:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061017" ; a owl:Class ; rdfs:label "hepatoblast differentiation" ; rdfs:subClassOf obo:GO_0030855, obo:GO_0048863, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001889 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000488 ] ) ] . obo:GO_0061024 obo:IAO_0000115 "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-02-08T02:43:11Z" ; oboInOwl:hasAlternativeId "GO:0016044", "GO:0044802" ; oboInOwl:hasExactSynonym "cellular membrane organisation", "cellular membrane organization", "membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "membrane organization and biogenesis", "single-organism membrane organization" ; oboInOwl:id "GO:0061024" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "membrane organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0061025 obo:IAO_0000115 "The membrane organization process that joins two lipid bilayers to form a single membrane." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-02-08T02:48:06Z" ; oboInOwl:hasAlternativeId "GO:0006944", "GO:0044801" ; oboInOwl:hasDbXref "Wikipedia:Lipid_bilayer_fusion" ; oboInOwl:hasExactSynonym "cellular membrane fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism membrane fusion" ; oboInOwl:id "GO:0061025" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "membrane fusion" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061024 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0061027 obo:IAO_0000115 "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-09T09:09:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061027" ; a owl:Class ; rdfs:label "umbilical cord development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002331 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002331 ] ) ] . obo:GO_0061032 obo:IAO_0000115 "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-09T09:52:49Z" ; oboInOwl:hasExactSynonym "epicardium development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061032" ; a owl:Class ; rdfs:label "visceral serous pericardium development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060039 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002425 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002425 ] ) ] . obo:GO_0061035 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-09T03:41:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061035" ; a owl:Class ; rdfs:label "regulation of cartilage development" ; rdfs:subClassOf obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051216 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051216 ] ) ] . obo:GO_0061036 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-09T03:41:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061036" ; a owl:Class ; rdfs:label "positive regulation of cartilage development" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0051240, obo:GO_0061035, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051216 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051216 ] ) ] . obo:GO_0061037 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-09T03:41:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061037" ; a owl:Class ; rdfs:label "negative regulation of cartilage development" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0051241, obo:GO_0061035, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051216 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051216 ] ) ] . obo:GO_0061038 obo:IAO_0000115 "The process in which anatomical structures of the uterus are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-22T11:12:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061038" ; a owl:Class ; rdfs:label "uterus morphogenesis" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060065 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000995 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000995 ] ) ] . obo:GO_0061040 obo:IAO_0000115 "The process in which a female gonad is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-22T11:29:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ovary morphogenesis" ; oboInOwl:id "GO:0061040" ; a owl:Class ; rdfs:label "female gonad morphogenesis" ; rdfs:subClassOf obo:GO_0035262, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008585 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000992 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000992 ] ) ] . obo:GO_0061046 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-25T10:41:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061046" ; a owl:Class ; rdfs:label "regulation of branching involved in lung morphogenesis" ; rdfs:subClassOf obo:GO_0060688, obo:GO_1905330, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060441 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060441 ] ) ] . obo:GO_0061047 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-25T10:50:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061047" ; a owl:Class ; rdfs:label "positive regulation of branching involved in lung morphogenesis" ; rdfs:subClassOf obo:GO_0051240, obo:GO_0061046, obo:GO_1905332, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060441 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060441 ] ) ] . obo:GO_0061048 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-25T10:51:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061048" ; a owl:Class ; rdfs:label "negative regulation of branching involved in lung morphogenesis" ; rdfs:subClassOf obo:GO_0051241, obo:GO_0061046, obo:GO_1905331, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060441 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060441 ] ) ] . obo:GO_0061049 obo:IAO_0000115 "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-25T12:56:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cardiac muscle cell hypertrophy", "cardiomyocyte growth", "heart muscle cell growth" ; oboInOwl:id "GO:0061049" ; a owl:Class ; rdfs:label "cell growth involved in cardiac muscle cell development" ; rdfs:subClassOf obo:GO_0048588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003301 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016049 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055013 ] ) ] . obo:GO_0061050 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-25T01:05:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061050" ; a owl:Class ; rdfs:label "regulation of cell growth involved in cardiac muscle cell development" ; rdfs:subClassOf obo:GO_0001558, obo:GO_0055021, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061049 ] ) ] . obo:GO_0061051 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-25T01:08:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061051" ; a owl:Class ; rdfs:label "positive regulation of cell growth involved in cardiac muscle cell development" ; rdfs:subClassOf obo:GO_0010613, obo:GO_0030307, obo:GO_0051155, obo:GO_0055023, obo:GO_0061050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0061049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0061049 ] ) ] . obo:GO_0061052 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-02-25T01:11:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061052" ; a owl:Class ; rdfs:label "negative regulation of cell growth involved in cardiac muscle cell development" ; rdfs:subClassOf obo:GO_0010614, obo:GO_0030308, obo:GO_0051154, obo:GO_0055022, obo:GO_0061050, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0061049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0061049 ] ) ] . obo:GO_0061053 obo:IAO_0000115 "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-02T12:05:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061053" ; a owl:Class ; rdfs:label "somite development" ; rdfs:subClassOf obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002329 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002329 ] ) ] . obo:GO_0061054 obo:IAO_0000115 "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-02T12:07:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061054" ; a owl:Class ; rdfs:label "dermatome development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061053 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004016 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004016 ] ) ] . obo:GO_0061055 obo:IAO_0000115 "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-02T12:11:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061055" ; a owl:Class ; rdfs:label "myotome development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061053 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003082 ] ) ] . obo:GO_0061056 obo:IAO_0000115 "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-02T12:12:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061056" ; a owl:Class ; rdfs:label "sclerotome development" ; rdfs:subClassOf obo:GO_0060485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061053 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003089 ] ) ] . obo:GO_0061061 obo:IAO_0000115 "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-09T08:55:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061061" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "muscle structure development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_6072 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005090 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_6072 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005090 ] ) ] . obo:GO_0061062 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T12:59:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061062" ; a owl:Class ; rdfs:label "regulation of nematode larval development" ; rdfs:subClassOf obo:GO_0048580, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002119 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002119 ] ) ] . obo:GO_0061063 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:03:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061063" ; a owl:Class ; rdfs:label "positive regulation of nematode larval development" ; rdfs:subClassOf obo:GO_0048582, obo:GO_0061062, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002119 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002119 ] ) ] . obo:GO_0061064 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:04:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061064" ; a owl:Class ; rdfs:label "negative regulation of nematode larval development" ; rdfs:subClassOf obo:GO_0048581, obo:GO_0061062, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002119 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002119 ] ) ] . obo:GO_0061065 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:07:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061065" ; a owl:Class ; rdfs:label "regulation of dauer larval development" ; rdfs:subClassOf obo:GO_0061062, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040024 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040024 ] ) ] . obo:GO_0061066 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:09:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061066" ; a owl:Class ; rdfs:label "positive regulation of dauer larval development" ; rdfs:subClassOf obo:GO_0061063, obo:GO_0061065, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040024 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040024 ] ) ] . obo:GO_0061067 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:10:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061067" ; a owl:Class ; rdfs:label "negative regulation of dauer larval development" ; rdfs:subClassOf obo:GO_0061064, obo:GO_0061065, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040024 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040024 ] ) ] . obo:GO_0061068 obo:IAO_0000115 "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-12T08:24:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061068" ; a owl:Class ; rdfs:label "urethra development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000057 ] ) ] . obo:GO_0061069 obo:IAO_0000115 "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-12T08:28:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061069" ; a owl:Class ; rdfs:label "male urethra development" ; rdfs:subClassOf obo:GO_0061068, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001333 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001333 ] ) ] . obo:GO_0061070 obo:IAO_0000115 "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-12T08:29:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061070" ; a owl:Class ; rdfs:label "female urethra development" ; rdfs:subClassOf obo:GO_0061068, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001334 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001334 ] ) ] . obo:GO_0061071 obo:IAO_0000115 "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-12T08:36:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061071" ; a owl:Class ; rdfs:label "urethra epithelium development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002325 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002325 ] ) ] . obo:GO_0061072 obo:IAO_0000115 "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-16T10:48:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061072" ; a owl:Class ; rdfs:label "iris morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048593 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001769 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001769 ] ) ] . obo:GO_0061073 obo:IAO_0000115 "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-16T10:55:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061073" ; a owl:Class ; rdfs:label "ciliary body morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048593 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001775 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001775 ] ) ] . obo:GO_0061074 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-16T11:47:05Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061074" ; a owl:Class ; rdfs:label "regulation of neural retina development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003407 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003407 ] ) ] . obo:GO_0061075 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-16T11:59:48Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061075" ; a owl:Class ; rdfs:label "positive regulation of neural retina development" ; rdfs:subClassOf obo:GO_0061074, obo:GO_1902868, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003407 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003407 ] ) ] . obo:GO_0061076 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-16T12:46:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061076" ; a owl:Class ; rdfs:label "negative regulation of neural retina development" ; rdfs:subClassOf obo:GO_0061074, obo:GO_1902867, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003407 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003407 ] ) ] . obo:GO_0061080 obo:IAO_0000115 "The progression of the right horn of the sinus venosus from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-04-08T02:45:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061080" ; a owl:Class ; rdfs:label "right horn of sinus venosus development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003235 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005092 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005092 ] ) ] . obo:GO_0061100 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-04-27T03:28:46Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061100" ; a owl:Class ; rdfs:label "lung neuroendocrine cell differentiation" ; rdfs:subClassOf obo:GO_0061101, obo:GO_0061140, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000223 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000223 ] ) ] . obo:GO_0061101 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-04-28T09:42:20Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061101" ; a owl:Class ; rdfs:label "neuroendocrine cell differentiation" ; rdfs:subClassOf obo:GO_0030182, obo:GO_0060563, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000165 ] ) ] . obo:GO_0061102 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-04-28T09:47:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "gastric neuroendocrine cell differentiation" ; oboInOwl:id "GO:0061102" ; a owl:Class ; rdfs:label "stomach neuroendocrine cell differentiation" ; rdfs:subClassOf obo:GO_0035883, obo:GO_0061101, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0062094 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000222 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000222 ] ) ] . obo:GO_0061105 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-04-29T12:19:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061105" ; a owl:Class ; rdfs:label "regulation of stomach neuroendocrine cell differentiation" ; rdfs:subClassOf obo:GO_0030856, obo:GO_0045664, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061102 ] ) ] . obo:GO_0061106 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-04-29T12:23:05Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061106" ; a owl:Class ; rdfs:label "negative regulation of stomach neuroendocrine cell differentiation" ; rdfs:subClassOf obo:GO_0002085, obo:GO_0045665, obo:GO_0061105, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0061102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0061102 ] ) ] . obo:GO_0061107 obo:IAO_0000115 "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-04-30T10:17:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061107" ; a owl:Class ; rdfs:label "seminal vesicle development" ; rdfs:subClassOf obo:GO_0048608, obo:GO_0048732, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000998 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000998 ] ) ] . obo:GO_0061108 obo:IAO_0000115 "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-04-30T10:19:54Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061108" ; a owl:Class ; rdfs:label "seminal vesicle epithelium development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0035295, obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061107 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004805 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004805 ] ) ] . obo:GO_0061113 obo:IAO_0000115 "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-05-05T11:55:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061113" ; a owl:Class ; rdfs:label "pancreas morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031016 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001264 ] ) ] . obo:GO_0061114 obo:IAO_0000115 "The process in which the branches of the pancreas are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-05-05T12:03:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061114" ; a owl:Class ; rdfs:label "branching involved in pancreas morphogenesis" ; rdfs:subClassOf obo:GO_0061138, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061113 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061138 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061113 ] ) ] . obo:GO_0061117 obo:IAO_0000115 "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-05-17T07:31:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061117" ; a owl:Class ; rdfs:label "negative regulation of heart growth" ; rdfs:subClassOf obo:GO_0046621, obo:GO_0060420, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060419 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060419 ] ) ] . obo:GO_0061130 obo:IAO_0000115 "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-05-17T09:33:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061130" ; a owl:Class ; rdfs:label "pancreatic bud formation" ; rdfs:subClassOf obo:GO_0048645, obo:GO_0061114, obo:GO_0072175, [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003922 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003922 ] ) ] . obo:GO_0061138 obo:IAO_0000115 "The process in which the anatomical structures of a branched epithelium are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-05-25T09:05:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061138" ; a owl:Class ; rdfs:label "morphogenesis of a branching epithelium" ; rdfs:subClassOf obo:GO_0001763, obo:GO_0002009 . obo:GO_0061140 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-05-25T09:28:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061140" ; a owl:Class ; rdfs:label "lung secretory cell differentiation" ; rdfs:subClassOf obo:GO_0060487, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000272 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000272 ] ) ] . obo:GO_0061141 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-05-25T09:31:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061141" ; a owl:Class ; rdfs:label "lung ciliated cell differentiation" ; rdfs:subClassOf obo:GO_0060487, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000271 ] ) ] . obo:GO_0061147 obo:IAO_0000115 "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-06-03T09:15:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061147" ; a owl:Class ; rdfs:label "endocardial endothelium development" ; rdfs:subClassOf obo:GO_0003158, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003157 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005316 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005316 ] ) ] . obo:GO_0061148 obo:IAO_0000115 "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-06-03T09:18:02Z" ; oboInOwl:hasExactSynonym "extracellular matrix organisation involved in endocardium development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061148" ; a owl:Class ; rdfs:label "extracellular matrix organization involved in endocardium development" ; rdfs:subClassOf obo:GO_0030198, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003157 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030198 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003157 ] ) ] . obo:GO_0061152 obo:IAO_0000115 "The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-06-07T09:58:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061152" ; a owl:Class ; rdfs:label "trachea submucosa development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060438 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002202 ] ) ] . obo:GO_0061153 obo:IAO_0000115 "The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-06-07T10:10:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061153" ; a owl:Class ; rdfs:label "trachea gland development" ; rdfs:subClassOf obo:GO_0048732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061152 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005203 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005203 ] ) ] . obo:GO_0061154 obo:IAO_0000115 "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-06-15T09:05:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061154" ; a owl:Class ; rdfs:label "endothelial tube morphogenesis" ; rdfs:subClassOf obo:GO_0003159, obo:GO_0060562, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003915 ] ) ] . obo:GO_0061155 obo:IAO_0000115 "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-06-15T09:09:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061155" ; a owl:Class ; rdfs:label "pulmonary artery endothelial tube morphogenesis" ; rdfs:subClassOf obo:GO_0061154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061156 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005317 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005317 ] ) ] . obo:GO_0061156 obo:IAO_0000115 "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-06-15T09:13:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061156" ; a owl:Class ; rdfs:label "pulmonary artery morphogenesis" ; rdfs:subClassOf obo:GO_0048844, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002012 ] ) ] . obo:GO_0061178 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-13T09:38:42Z" ; oboInOwl:hasExactSynonym "regulation of insulin secretion in response to glucose" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061178" ; a owl:Class ; rdfs:label "regulation of insulin secretion involved in cellular response to glucose stimulus" ; rdfs:subClassOf obo:GO_0050796, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035773 ] ) ] . obo:GO_0061179 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-13T09:41:46Z" ; oboInOwl:hasExactSynonym "negative regulation of insulin secretion involved in cellular response to glucose" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of insulin secretion in response to glucose" ; oboInOwl:id "GO:0061179" ; a owl:Class ; rdfs:label "negative regulation of insulin secretion involved in cellular response to glucose stimulus" ; rdfs:subClassOf obo:GO_0046676, obo:GO_0048585, obo:GO_0061178, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035773 ] ) ] . obo:GO_0061181 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-14T08:28:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061181" ; a owl:Class ; rdfs:label "regulation of chondrocyte development" ; rdfs:subClassOf obo:GO_0032330, obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002063 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002063 ] ) ] . obo:GO_0061182 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-14T08:33:05Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061182" ; a owl:Class ; rdfs:label "negative regulation of chondrocyte development" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0032331, obo:GO_0061181, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002063 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002063 ] ) ] . obo:GO_0061183 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-14T08:40:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061183" ; a owl:Class ; rdfs:label "regulation of dermatome development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061054 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061054 ] ) ] . obo:GO_0061184 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-14T08:42:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061184" ; a owl:Class ; rdfs:label "positive regulation of dermatome development" ; rdfs:subClassOf obo:GO_0040019, obo:GO_0061183, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0061054 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0061054 ] ) ] . obo:GO_0061185 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-14T08:43:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061185" ; a owl:Class ; rdfs:label "negative regulation of dermatome development" ; rdfs:subClassOf obo:GO_0045992, obo:GO_0061183, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0061054 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0061054 ] ) ] . obo:GO_0061189 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-14T09:17:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061189" ; a owl:Class ; rdfs:label "positive regulation of sclerotome development" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0061190, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0061056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0061056 ] ) ] . obo:GO_0061190 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-14T09:19:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061190" ; a owl:Class ; rdfs:label "regulation of sclerotome development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061056 ] ) ] . obo:GO_0061205 obo:IAO_0000115 "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-07-30T10:54:47Z" ; oboInOwl:hasExactSynonym "Mullerian duct development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061205" ; a owl:Class ; rdfs:label "paramesonephric duct development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0035295, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003890 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003890 ] ) ] . obo:GO_0061206 obo:IAO_0000115 "The process in which the anatomical structures of the mesonephros are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:11:10Z" ; oboInOwl:hasExactSynonym "Wolffian body morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061206" ; a owl:Class ; rdfs:label "mesonephros morphogenesis" ; rdfs:subClassOf obo:GO_0060993, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000080 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000080 ] ) ] . obo:GO_0061208 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:21:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061208" ; a owl:Class ; rdfs:label "cell differentiation involved in mesonephros development" ; rdfs:subClassOf obo:GO_0061005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ] ) ] . obo:GO_0061209 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:22:46Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061209" ; a owl:Class ; rdfs:label "cell proliferation involved in mesonephros development" ; rdfs:subClassOf obo:GO_0072111, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ] ) ] . obo:GO_0061210 obo:IAO_0000115 "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:24:08Z" ; oboInOwl:hasExactSynonym "cell-cell signalling involved in mesonephros development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061210" ; a owl:Class ; rdfs:label "cell-cell signaling involved in mesonephros development" ; rdfs:subClassOf obo:GO_0060995, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ] ) ] . obo:GO_0061211 obo:IAO_0000115 "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:25:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061211" ; a owl:Class ; rdfs:label "mesonephric collecting duct development" ; rdfs:subClassOf obo:GO_0072044, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005319 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005319 ] ) ] . obo:GO_0061213 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:39:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061213" ; a owl:Class ; rdfs:label "positive regulation of mesonephros development" ; rdfs:subClassOf obo:GO_0061217, obo:GO_0090184, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001823 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001823 ] ) ] . obo:GO_0061214 obo:IAO_0000115 "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:29:54Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061214" ; a owl:Class ; rdfs:label "mesonephric smooth muscle tissue development" ; rdfs:subClassOf obo:GO_0072194, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005321 ] ) ] . obo:GO_0061215 obo:IAO_0000115 "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:31:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061215" ; a owl:Class ; rdfs:label "mesonephric nephron development" ; rdfs:subClassOf obo:GO_0072006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005322 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005322 ] ) ] . obo:GO_0061217 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:35:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061217" ; a owl:Class ; rdfs:label "regulation of mesonephros development" ; rdfs:subClassOf obo:GO_0090183, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001823 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001823 ] ) ] . obo:GO_0061218 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:43:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061218" ; a owl:Class ; rdfs:label "negative regulation of mesonephros development" ; rdfs:subClassOf obo:GO_0061217, obo:GO_0090185, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001823 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001823 ] ) ] . obo:GO_0061219 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-17T03:45:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061219" ; a owl:Class ; rdfs:label "mesonephric mesenchyme development" ; rdfs:subClassOf obo:GO_0072074, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005323 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005323 ] ) ] . obo:GO_0061221 obo:IAO_0000115 "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-19T01:17:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061221" ; a owl:Class ; rdfs:label "mesonephric mesenchyme morphogenesis" ; rdfs:subClassOf obo:GO_0072131, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061219 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005323 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005323 ] ) ] . obo:GO_0061227 obo:IAO_0000115 "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-19T02:22:22Z" ; oboInOwl:hasExactSynonym "mesonephros pattern specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mesonephros pattern formation" ; oboInOwl:id "GO:0061227" ; a owl:Class ; rdfs:label "pattern specification involved in mesonephros development" ; rdfs:subClassOf obo:GO_0061004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007389 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ] ) ] . obo:GO_0061228 obo:IAO_0000115 "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-19T02:26:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061228" ; a owl:Class ; rdfs:label "mesonephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061206 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061215 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005322 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005322 ] ) ] . obo:GO_0061235 obo:IAO_0000115 "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-19T02:57:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061235" ; a owl:Class ; rdfs:label "mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072038, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061228 ] . obo:GO_0061241 obo:IAO_0000115 "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-19T03:11:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061241" ; a owl:Class ; rdfs:label "mesonephric nephron epithelium development" ; rdfs:subClassOf obo:GO_0072009, obo:GO_0072163, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061215 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005330 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005330 ] ) ] . obo:GO_0061243 obo:IAO_0000115 "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-19T03:20:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061243" ; a owl:Class ; rdfs:label "mesonephric renal vesicle morphogenesis" ; rdfs:subClassOf obo:GO_0072077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061228 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005331 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005331 ] ) ] . obo:GO_0061261 obo:IAO_0000115 "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-30T02:35:15Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mesonephric mesenchyme to epithelial transition" ; oboInOwl:id "GO:0061261" ; a owl:Class ; rdfs:label "mesenchymal to epithelial transition involved in mesonephros morphogenesis" ; rdfs:subClassOf obo:GO_0035850, obo:GO_0060231, obo:GO_0061208, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061206 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060231 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061206 ] ) ] . obo:GO_0061262 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-30T02:41:20Z" ; oboInOwl:hasExactSynonym "mesonephros formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061262" ; a owl:Class ; rdfs:label "mesonephric renal vesicle formation" ; rdfs:subClassOf obo:GO_0072033, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061243 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005331 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005331 ] ) ] . obo:GO_0061271 obo:IAO_0000115 "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-08-30T03:26:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061271" ; a owl:Class ; rdfs:label "mesenchymal to epithelial transition involved in mesonephric renal vesicle formation" ; rdfs:subClassOf obo:GO_0061261, obo:GO_0072036, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061262 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060231 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061262 ] ) ] . obo:GO_0061285 obo:IAO_0000115 "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-02T01:50:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061285" ; a owl:Class ; rdfs:label "mesonephric capsule development" ; rdfs:subClassOf obo:GO_0072127, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006170 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006170 ] ) ] . obo:GO_0061286 obo:IAO_0000115 "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-02T01:53:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061286" ; a owl:Class ; rdfs:label "mesonephric capsule morphogenesis" ; rdfs:subClassOf obo:GO_0072128, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061285 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0006170 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0006170 ] ) ] . obo:GO_0061287 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-02T01:55:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061287" ; a owl:Class ; rdfs:label "mesonephric capsule formation" ; rdfs:subClassOf obo:GO_0072129, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061286 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0006170 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0006170 ] ) ] . obo:GO_0061295 obo:IAO_0000115 "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-06T09:48:56Z" ; oboInOwl:hasExactSynonym "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" ; oboInOwl:hasNarrowSynonym "regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061295" ; a owl:Class ; rdfs:label "regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072039, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061235 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1901146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1901146 ] ) ] . obo:GO_0061296 obo:IAO_0000115 "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-06T09:54:49Z" ; oboInOwl:hasExactSynonym "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" ; oboInOwl:hasNarrowSynonym "negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061296" ; a owl:Class ; rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0061218, obo:GO_0061295, obo:GO_0072040, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0061235 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1901146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1901146 ] ) ] . obo:GO_0061297 obo:IAO_0000115 "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-06T09:58:59Z" ; oboInOwl:hasExactSynonym "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis" ; oboInOwl:hasNarrowSynonym "positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061297" ; a owl:Class ; rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0061213, obo:GO_0061295, obo:GO_0072041, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0061235 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1901146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1901146 ] ) ] . obo:GO_0061298 obo:IAO_0000115 "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-06T03:27:06Z" ; oboInOwl:hasExactSynonym "retinal vasculature development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061298" ; a owl:Class ; rdfs:label "retina vasculature development in camera-type eye" ; rdfs:subClassOf obo:GO_0001944, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060041 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004864 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004864 ] ) ] . obo:GO_0061299 obo:IAO_0000115 "The process in which the vasculature of the retina is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-06T03:28:25Z" ; oboInOwl:hasExactSynonym "retinal vasculature morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061299" ; a owl:Class ; rdfs:label "retina vasculature morphogenesis in camera-type eye" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061298 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004864 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004864 ] ) ] . obo:GO_0061303 obo:IAO_0000115 "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-14T02:09:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061303" ; a owl:Class ; rdfs:label "cornea development in camera-type eye" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043010 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000964 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000964 ] ) ] . obo:GO_0061304 obo:IAO_0000115 "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-16T09:02:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061304" ; a owl:Class ; rdfs:label "retinal blood vessel morphogenesis" ; rdfs:subClassOf obo:GO_0048514, obo:GO_0061299, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003501 ] ) ] . obo:GO_0061307 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-23T08:50:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061307" ; a owl:Class ; rdfs:label "cardiac neural crest cell differentiation involved in heart development" ; rdfs:subClassOf obo:GO_0014033, obo:GO_0035051 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0014033 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ] ) ] . obo:GO_0061308 obo:IAO_0000115 "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-23T09:01:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061308" ; a owl:Class ; rdfs:label "cardiac neural crest cell development involved in heart development" ; rdfs:subClassOf obo:GO_0014032, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061307 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0014032 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007507 ] ) ] . obo:GO_0061309 obo:IAO_0000115 "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-23T09:08:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061309" ; a owl:Class ; rdfs:label "cardiac neural crest cell development involved in outflow tract morphogenesis" ; rdfs:subClassOf obo:GO_0061308, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003151 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0014032 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003151 ] ) ] . obo:GO_0061323 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-28T09:05:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061323" ; a owl:Class ; rdfs:label "cell proliferation involved in heart morphogenesis" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ] ) ] . obo:GO_0061325 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-28T09:29:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061325" ; a owl:Class ; rdfs:label "cell proliferation involved in outflow tract morphogenesis" ; rdfs:subClassOf obo:GO_0061323, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003151 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003151 ] ) ] . obo:GO_0061326 obo:IAO_0000115 "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-28T12:50:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061326" ; a owl:Class ; rdfs:label "renal tubule development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0009773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0009773 ] ) ] . obo:GO_0061333 obo:IAO_0000115 "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-28T01:43:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061333" ; a owl:Class ; rdfs:label "renal tubule morphogenesis" ; rdfs:subClassOf obo:GO_0060562, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061326 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0009773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0009773 ] ) ] . obo:GO_0061337 obo:IAO_0000115 "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-29T08:46:05Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061337" ; a owl:Class ; rdfs:label "cardiac conduction" ; rdfs:subClassOf obo:GO_0008016 . obo:GO_0061343 obo:IAO_0000115 "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-29T11:34:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061343" ; a owl:Class ; rdfs:label "cell adhesion involved in heart morphogenesis" ; rdfs:subClassOf obo:GO_0007155, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007155 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ] ) ] . obo:GO_0061344 obo:IAO_0000115 "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-29T11:35:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061344" ; a owl:Class ; rdfs:label "regulation of cell adhesion involved in heart morphogenesis" ; rdfs:subClassOf obo:GO_0030155, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061343 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0061343 ] ) ] . obo:GO_0061351 obo:IAO_0000115 "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-10-01T11:06:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061351" ; a owl:Class ; rdfs:label "neural precursor cell proliferation" ; rdfs:subClassOf obo:GO_0008283 . obo:GO_0061385 obo:IAO_0000115 "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-02-10T01:41:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061385" ; a owl:Class ; rdfs:label "fibroblast proliferation involved in heart morphogenesis" ; rdfs:subClassOf obo:GO_0048144, obo:GO_0061323 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048144 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003007 ] ) ] . obo:GO_0061387 obo:IAO_0000115 "Any process that modulates the extent of cell growth." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-07-14T10:15:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061387" ; a owl:Class ; rdfs:label "regulation of extent of cell growth" ; rdfs:subClassOf obo:GO_0001558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008361 ] . obo:GO_0061437 obo:IAO_0000115 "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-03-08T12:16:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061437" ; a owl:Class ; rdfs:label "renal system vasculature development" ; rdfs:subClassOf obo:GO_0001944, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072001 ] . obo:GO_0061438 obo:IAO_0000115 "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-03-08T12:21:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061438" ; a owl:Class ; rdfs:label "renal system vasculature morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061437 ] . obo:GO_0061439 obo:IAO_0000115 "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-03-08T12:30:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061439" ; a owl:Class ; rdfs:label "kidney vasculature morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061438 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061440 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0006544 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0006544 ] ) ] . obo:GO_0061440 obo:IAO_0000115 "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-03-08T12:39:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061440" ; a owl:Class ; rdfs:label "kidney vasculature development" ; rdfs:subClassOf obo:GO_0061437, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006544 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006544 ] ) ] . obo:GO_0061441 obo:IAO_0000115 "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-03-08T12:42:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061441" ; a owl:Class ; rdfs:label "renal artery morphogenesis" ; rdfs:subClassOf obo:GO_0048844, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061439 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001184 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001184 ] ) ] . obo:GO_0061448 obo:IAO_0000115 "The progression of a connective tissue over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-03-22T12:53:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061448" ; a owl:Class ; rdfs:label "connective tissue development" ; rdfs:subClassOf obo:GO_0009888, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002384 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002384 ] ) ] . obo:GO_0061450 obo:IAO_0000115 "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-07-10T08:38:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061450" ; a owl:Class ; rdfs:label "trophoblast cell migration" ; rdfs:subClassOf obo:GO_0001667, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007566 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000351 ] ) ] . obo:GO_0061453 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-07-20T08:20:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ICC differentiation" ; oboInOwl:id "GO:0061453" ; a owl:Class ; rdfs:label "interstitial cell of Cajal differentiation" ; rdfs:subClassOf obo:GO_0060563, obo:GO_0060575, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002088 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0002088 ] ) ] . obo:GO_0061458 obo:IAO_0000115 "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-08-22T17:47:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061458" ; a owl:Class ; rdfs:label "reproductive system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000990 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000990 ] ) ] . obo:GO_0061462 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within a lysosome." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-10-05T10:50:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061462" ; a owl:Class ; rdfs:label "protein localization to lysosome" ; rdfs:subClassOf obo:GO_0072665, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005764 ] ) ] . obo:GO_0061469 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-11-01T13:16:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061469" ; a owl:Class ; rdfs:label "regulation of type B pancreatic cell proliferation" ; rdfs:subClassOf obo:GO_0050678, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044342 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044342 ] ) ] . obo:GO_0061484 obo:IAO_0000115 "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-12-04T09:41:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061484" ; a owl:Class ; rdfs:label "hematopoietic stem cell homeostasis" ; rdfs:subClassOf obo:GO_0048872, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000037 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048872 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000037 ] ) ] . obo:GO_0061512 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within a cilium." ; obo:RO_0002161 obo:NCBITaxon_3176, obo:NCBITaxon_3312, obo:NCBITaxon_3378, obo:NCBITaxon_3398, obo:NCBITaxon_4890, obo:NCBITaxon_5782 ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-03-22T15:41:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061512" ; a owl:Class ; rdfs:label "protein localization to cilium" ; rdfs:subClassOf obo:GO_0033365, [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ] ], [ a owl:Class ; owl:complementOf [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3176 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3312 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3378 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_3398 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_4890 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom [ a owl:Class ; owl:complementOf obo:NCBITaxon_5782 ] ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005929 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3176 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3312 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3378 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_3398 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_4890 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_5782 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:GO_0061515 obo:IAO_0000115 "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-04-18T13:03:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061515" ; a owl:Class ; rdfs:label "myeloid cell development" ; rdfs:subClassOf obo:GO_0030097, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030099 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000763 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048468 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000763 ] ) ] . obo:GO_0061523 obo:IAO_0000115 "A cellular process that results in the breakdown of a cilium." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-04-18T14:59:59Z" ; oboInOwl:hasExactSynonym "cilium resorption" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061523" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "cilium disassembly" ; rdfs:subClassOf obo:GO_0044782, obo:GO_1903008, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005929 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:GO_0061525 obo:IAO_0000115 "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-06-14T11:22:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061525" ; a owl:Class ; rdfs:label "hindgut development" ; rdfs:subClassOf obo:GO_0048565, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001046 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001046 ] ) ] . obo:GO_0061526 obo:IAO_0000115 "The regulated release of acetylcholine by a cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-06-21T15:40:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061526" ; a owl:Class ; rdfs:label "acetylcholine secretion" ; rdfs:subClassOf obo:GO_0015870, obo:GO_0023061 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_15355 ] ) ] . obo:GO_0061527 obo:IAO_0000115 "The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-06-21T15:43:15Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061527" ; a owl:Class ; rdfs:label "dopamine secretion, neurotransmission" ; rdfs:subClassOf obo:GO_0007269, obo:GO_0099124, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001963 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007269 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59905 ] ) ] . obo:GO_0061533 obo:IAO_0000115 "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-06-21T16:05:08Z" ; oboInOwl:hasExactSynonym "noradrenaline secretion, neurotransmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061533" ; a owl:Class ; rdfs:label "norepinephrine secretion, neurotransmission" ; rdfs:subClassOf obo:GO_0048243, obo:GO_0160043 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007269 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0061534 obo:IAO_0000115 "The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-06-21T16:10:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061534" ; a owl:Class ; rdfs:label "gamma-aminobutyric acid secretion, neurotransmission" ; rdfs:subClassOf obo:GO_0007269, obo:GO_0014051, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007269 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59888 ] ) ] . obo:GO_0061548 obo:IAO_0000115 "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:36:12Z" ; oboInOwl:hasNarrowSynonym "gangliogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ganglia development" ; oboInOwl:id "GO:0061548" ; a owl:Class ; rdfs:label "ganglion development" ; rdfs:subClassOf obo:GO_0009888, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000045 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000045 ] ) ] . obo:GO_0061549 obo:IAO_0000115 "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:38:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "sympathetic ganglia development" ; oboInOwl:id "GO:0061549" ; a owl:Class ; rdfs:label "sympathetic ganglion development" ; rdfs:subClassOf obo:GO_0061548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048485 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001806 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001806 ] ) ] . obo:GO_0061550 obo:IAO_0000115 "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:40:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cranial ganglia development" ; oboInOwl:id "GO:0061550" ; a owl:Class ; rdfs:label "cranial ganglion development" ; rdfs:subClassOf obo:GO_0061548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021545 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001714 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001714 ] ) ] . obo:GO_0061551 obo:IAO_0000115 "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:42:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "trigeminal ganglia development" ; oboInOwl:id "GO:0061551" ; a owl:Class ; rdfs:label "trigeminal ganglion development" ; rdfs:subClassOf obo:GO_0061550, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001675 ] ) ] . obo:GO_0061552 obo:IAO_0000115 "The process in which the anatomical structures of ganglion are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:44:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ganglia morphogenesis" ; oboInOwl:id "GO:0061552" ; a owl:Class ; rdfs:label "ganglion morphogenesis" ; rdfs:subClassOf obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061548 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000045 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000045 ] ) ] . obo:GO_0061553 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:45:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ganglia maturation" ; oboInOwl:id "GO:0061553" ; a owl:Class ; rdfs:label "ganglion maturation" ; rdfs:subClassOf obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061548 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000045 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071695 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0000045 ] ) ] . obo:GO_0061554 obo:IAO_0000115 "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:51:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ganglia formation" ; oboInOwl:id "GO:0061554" ; a owl:Class ; rdfs:label "ganglion formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061552 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000045 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000045 ] ) ] . obo:GO_0061556 obo:IAO_0000115 "The process in which the anatomical structure of a trigeminal ganglion is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:57:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "trigeminal ganglia morphogenesis" ; oboInOwl:id "GO:0061556" ; a owl:Class ; rdfs:label "trigeminal ganglion morphogenesis" ; rdfs:subClassOf obo:GO_0061559, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021636 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061551 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001675 ] ) ] . obo:GO_0061557 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:58:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "trigeminal ganglia maturation" ; oboInOwl:id "GO:0061557" ; a owl:Class ; rdfs:label "trigeminal ganglion maturation" ; rdfs:subClassOf obo:GO_0061558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021635 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061551 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071695 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001675 ] ) ] . obo:GO_0061558 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T08:59:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cranial ganglia maturation" ; oboInOwl:id "GO:0061558" ; a owl:Class ; rdfs:label "cranial ganglion maturation" ; rdfs:subClassOf obo:GO_0061553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021605 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061550 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001714 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071695 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001714 ] ) ] . obo:GO_0061559 obo:IAO_0000115 "The process in which the anatomical structure of a cranial ganglion is generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T09:02:15Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cranial ganglia morphogenesis" ; oboInOwl:id "GO:0061559" ; a owl:Class ; rdfs:label "cranial ganglion morphogenesis" ; rdfs:subClassOf obo:GO_0061552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0021602 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061550 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001714 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001714 ] ) ] . obo:GO_0061560 obo:IAO_0000115 "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T09:07:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cranial ganglia formation" ; oboInOwl:id "GO:0061560" ; a owl:Class ; rdfs:label "cranial ganglion formation" ; rdfs:subClassOf obo:GO_0061554, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061559 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001714 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001714 ] ) ] . obo:GO_0061561 obo:IAO_0000115 "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-10T09:08:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "trigeminal ganglia formation" ; oboInOwl:id "GO:0061561" ; a owl:Class ; rdfs:label "trigeminal ganglion formation" ; rdfs:subClassOf obo:GO_0061560, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061556 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001675 ] ) ] . obo:GO_0061564 obo:IAO_0000115 "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-18T14:43:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061564" ; a owl:Class ; rdfs:label "axon development" ; rdfs:subClassOf obo:GO_0031175 . obo:GO_0061572 obo:IAO_0000115 "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-08-02T11:24:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "actin filament cable organization" ; oboInOwl:id "GO:0061572" ; a owl:Class ; rdfs:label "actin filament bundle organization" ; rdfs:subClassOf obo:GO_0007015, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0032432 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0032432 ] ) ] . obo:GO_0061580 obo:IAO_0000115 "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-12-23T07:26:54Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061580" ; a owl:Class ; rdfs:label "colon epithelial cell migration" ; rdfs:subClassOf obo:GO_0061582, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0011108 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0011108 ] ) ] . obo:GO_0061581 obo:IAO_0000115 "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-12-23T07:28:29Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061581" ; a owl:Class ; rdfs:label "corneal epithelial cell migration" ; rdfs:subClassOf obo:GO_0010631, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000575 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000575 ] ) ] . obo:GO_0061582 obo:IAO_0000115 "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-12-23T07:30:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061582" ; a owl:Class ; rdfs:label "intestinal epithelial cell migration" ; rdfs:subClassOf obo:GO_0010631, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0002563 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0002563 ] ) ] . obo:GO_0061626 obo:IAO_0000115 "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2014-05-09T15:34:06Z" ; oboInOwl:hasBroadSynonym "aortic arch artery morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061626" ; a owl:Class ; rdfs:label "pharyngeal arch artery morphogenesis" ; rdfs:subClassOf obo:GO_0048844, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060037 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004363 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004363 ] ) ] . obo:GO_0061640 obo:IAO_0000115 "A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2014-08-22T14:21:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061640" ; a owl:Class ; rdfs:label "cytoskeleton-dependent cytokinesis" ; rdfs:subClassOf obo:GO_0000910 . obo:GO_0061642 obo:IAO_0000115 "The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2014-08-29T08:21:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061642" ; a owl:Class ; rdfs:label "chemoattraction of axon" ; rdfs:subClassOf obo:GO_0050918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050918 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ] ) ] . obo:GO_0061643 obo:IAO_0000115 "The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2014-08-29T08:35:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061643" ; a owl:Class ; rdfs:label "chemorepulsion of axon" ; rdfs:subClassOf obo:GO_0050919, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050919 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ] ) ] . obo:GO_0061673 obo:IAO_0000115 "Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2014-12-08T18:27:20Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0061673" ; a owl:Class ; rdfs:label "mitotic spindle astral microtubule" ; rdfs:subClassOf obo:GO_0000235, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072686 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000235 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072686 ] ) ] . obo:GO_0061682 obo:IAO_0000115 "The process in which the anatomical structures of a seminal vesicle are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2015-03-04T13:33:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061682" ; a owl:Class ; rdfs:label "seminal vesicle morphogenesis" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022612, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061107 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000998 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000998 ] ) ] . obo:GO_0061683 obo:IAO_0000115 "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2015-03-04T13:39:47Z" ; oboInOwl:hasExactSynonym "gonecyst branching morphogenesis", "seminal gland branching morphogenesis", "seminal vesicle branching", "seminal vesicle branching morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061683" ; a owl:Class ; rdfs:label "branching involved in seminal vesicle morphogenesis" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0061138, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061108 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061682 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061138 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061682 ] ) ] . obo:GO_0061687 obo:IAO_0000115 "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2015-03-09T09:16:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061687" ; a owl:Class ; rdfs:label "detoxification of inorganic compound" ; rdfs:subClassOf obo:GO_0098754, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_24835 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098754 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_24835 ] ) ] . obo:GO_0061695 obo:IAO_0000115 "A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor)." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2015-05-06T11:22:38Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0061695" ; a owl:Class ; rdfs:label "transferase complex, transferring phosphorus-containing groups" ; rdfs:subClassOf obo:GO_1990234, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0016772 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0016772 ] ) ] . obo:GO_0061726 obo:IAO_0000115 "The disaggregation of a mitochondrion into its constituent components." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2015-07-08T13:59:16Z" ; oboInOwl:hasExactSynonym "mitochondrion degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061726" ; a owl:Class ; rdfs:label "mitochondrion disassembly" ; rdfs:subClassOf obo:GO_0007005, obo:GO_1903008 . obo:GO_0061792 obo:IAO_0000115 "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2016-09-09T13:24:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061792" ; a owl:Class ; rdfs:label "secretory granule maturation" ; rdfs:subClassOf obo:GO_0021700, obo:GO_0033363, [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:GO_0030141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:GO_0030141 ] ) ] . obo:GO_0061853 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of neuroblast migration." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-03-08T18:17:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061853" ; a owl:Class ; rdfs:label "regulation of neuroblast migration" ; rdfs:subClassOf obo:GO_0030334, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097402 ] ) ] . obo:GO_0061854 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of neuroblast migration." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-03-08T18:22:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061854" ; a owl:Class ; rdfs:label "positive regulation of neuroblast migration" ; rdfs:subClassOf obo:GO_0030335, obo:GO_0061853, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097402 ] ) ] . obo:GO_0061855 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-03-08T18:26:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061855" ; a owl:Class ; rdfs:label "negative regulation of neuroblast migration" ; rdfs:subClassOf obo:GO_0030336, obo:GO_0061853, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097402 ] ) ] . obo:GO_0061856 obo:IAO_0000115 "A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-03-14T16:08:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061856" ; a owl:Class ; rdfs:label "Golgi calcium ion transmembrane transport" ; rdfs:subClassOf obo:GO_0032472, obo:GO_0070588 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002344 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29108 ] ) ] . obo:GO_0061900 obo:IAO_0000115 "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-06-13T13:06:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061900" ; a owl:Class ; rdfs:label "glial cell activation" ; rdfs:subClassOf obo:GO_0001775, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0150076 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000125 ] ) ] . obo:GO_0061912 obo:IAO_0000115 "The macroautophagy process in which specific structures are targeted by the autophagy process." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-07-07T17:27:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061912" ; a owl:Class ; rdfs:label "selective autophagy" ; rdfs:subClassOf obo:GO_0016236 . obo:GO_0061919 obo:IAO_0000115 "A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-07-13T19:42:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061919" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "process utilizing autophagic mechanism" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0061938 obo:IAO_0000115 "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-09-08T13:22:26Z" ; oboInOwl:hasExactSynonym "somatodendritic protein localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061938" ; a owl:Class ; rdfs:label "protein localization to somatodendritic compartment" ; rdfs:subClassOf obo:GO_0008104, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0036477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0036477 ] ) ] . obo:GO_0061951 obo:IAO_0000115 "The directed movement of a protein to a specific location in a plasma membrane." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-10-26T12:55:15Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061951" ; a owl:Class ; rdfs:label "establishment of protein localization to plasma membrane" ; rdfs:subClassOf obo:GO_0072659, obo:GO_0090150 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045184 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0061971 obo:IAO_0000115 "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-02-12T18:10:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061971" ; a owl:Class ; rdfs:label "replacement bone morphogenesis" ; rdfs:subClassOf obo:GO_0060349, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0012075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060349 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0012075 ] ) ] . obo:GO_0061972 obo:IAO_0000115 "The process in which bone which forms superficially in the organism are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-02-12T18:16:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061972" ; a owl:Class ; rdfs:label "dermal bone morphogenesis" ; rdfs:subClassOf obo:GO_0061973, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0008907 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060349 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0008907 ] ) ] . obo:GO_0061973 obo:IAO_0000115 "The process in which bone which forms deep in the organism are generated and organized." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-02-12T18:21:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061973" ; a owl:Class ; rdfs:label "membrane bone morphogenesis" ; rdfs:subClassOf obo:GO_0060349, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007842 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060349 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0007842 ] ) ] . obo:GO_0061982 obo:IAO_0000115 "A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-02-14T22:27:20Z" ; oboInOwl:hasExactSynonym "first meiotic cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061982" ; a owl:Class ; rdfs:label "meiosis I cell cycle process" ; rdfs:subClassOf obo:GO_1903046 . obo:GO_0061983 obo:IAO_0000115 "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-02-14T22:37:44Z" ; oboInOwl:hasExactSynonym "second meiotic division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061983" ; a owl:Class ; rdfs:label "meiosis II cell cycle process" ; rdfs:subClassOf obo:GO_1903046 . obo:GO_0062012 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-03-19T14:11:54Z" ; oboInOwl:hasExactSynonym "regulation of small molecule metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062012" ; a owl:Class ; rdfs:label "regulation of small molecule metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044281 ] ) ] . obo:GO_0062013 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-03-19T14:25:10Z" ; oboInOwl:hasExactSynonym "positive regulation of small molecule metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062013" ; a owl:Class ; rdfs:label "positive regulation of small molecule metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0062012, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044281 ] ) ] . obo:GO_0062014 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-03-19T14:27:23Z" ; oboInOwl:hasExactSynonym "negative regulation of small molecule metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062014" ; a owl:Class ; rdfs:label "negative regulation of small molecule metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0062012, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044281 ] ) ] . obo:GO_0062023 obo:IAO_0000115 "An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-04-13T12:47:21Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0062023" ; a owl:Class ; rdfs:label "collagen-containing extracellular matrix" ; rdfs:subClassOf obo:GO_0031012, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] . obo:GO_0062033 obo:IAO_0000115 "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-04-23T14:32:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062033" ; a owl:Class ; rdfs:label "positive regulation of mitotic sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033047, obo:GO_0051984, obo:GO_2001252, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000070 ] ) ] . obo:GO_0062094 obo:IAO_0000115 "The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-11-20T18:15:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062094" ; a owl:Class ; rdfs:label "stomach development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048565 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000945 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000945 ] ) ] . obo:GO_0062125 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2019-05-30T16:45:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062125" ; a owl:Class ; rdfs:label "regulation of mitochondrial gene expression" ; rdfs:subClassOf obo:GO_0010468, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140053 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140053 ] ) ] . obo:GO_0062149 obo:IAO_0000115 "The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2019-09-13T13:48:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062149" ; a owl:Class ; rdfs:label "detection of stimulus involved in sensory perception of pain" ; rdfs:subClassOf obo:GO_0050906, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019233 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051606 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019233 ] ) ] . obo:GO_0062197 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2019-12-10T14:42:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062197" ; a owl:Class ; rdfs:label "cellular response to chemical stress" ; rdfs:subClassOf obo:GO_0033554, obo:GO_0070887 . obo:GO_0062237 obo:IAO_0000115 "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2020-04-20T13:58:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062237" ; a owl:Class ; rdfs:label "protein localization to postsynapse" ; rdfs:subClassOf obo:GO_0035418, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0098794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0098794 ] ) ] . obo:GO_0065002 obo:IAO_0000115 "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "intracellular membrane translocation of a protein", "intracellular protein membrane transport", "intracellular protein transport across a membrane" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0065002" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "intracellular protein transmembrane transport" ; rdfs:subClassOf obo:GO_0006886, obo:GO_0071806 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0065003 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22580"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006461", "GO:0034622", "GO:0043623" ; oboInOwl:hasExactSynonym "cellular protein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular macromolecule complex assembly", "cellular protein-containing complex assembly", "chaperone activity", "macromolecular complex assembly", "macromolecule complex assembly", "protein complex assembly", "protein complex formation" ; oboInOwl:id "GO:0065003" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "protein-containing complex assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0043933, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0032991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0032991 ] ) ] . obo:GO_0065004 obo:IAO_0000115 "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex." ; oboInOwl:hasExactSynonym "DNA-protein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0065004" ; a owl:Class ; rdfs:label "protein-DNA complex assembly" ; rdfs:subClassOf obo:GO_0065003, obo:GO_0071824, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0032993 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0032993 ] ) ] . obo:GO_0065007 obo:IAO_0000115 "Any process that modulates a measurable attribute of any biological process, quality or function." ; oboInOwl:hasBroadSynonym "regulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0065007" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:label "biological regulation" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0065008 obo:IAO_0000115 "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." ; oboInOwl:hasExactSynonym "regulation of biological attribute", "regulation of biological characteristic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0065008" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "regulation of biological quality" ; rdfs:subClassOf obo:GO_0065007 . obo:GO_0065009 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ; oboInOwl:hasExactSynonym "regulation of a molecular function" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0065009" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir, go:goslim_plant, go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of molecular function" ; rdfs:subClassOf obo:GO_0065007, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003674 ] ) ] . obo:GO_0065010 obo:IAO_0000115 "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell." ; oboInOwl:hasExactSynonym "extracellular membrane-enclosed organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0065010" ; a owl:Class ; rdfs:label "extracellular membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043227, obo:GO_0043230 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043227 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005576 ] ) ] . obo:GO_0070013 obo:IAO_0000115 "An organelle lumen that is part of an intracellular organelle." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0070013" ; a owl:Class ; rdfs:label "intracellular organelle lumen" ; rdfs:subClassOf obo:GO_0043233, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043229 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031974 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043229 ] ) ] . obo:GO_0070050 obo:IAO_0000115 "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24218"^^xsd:anyURI ; oboInOwl:hasExactSynonym "neuron maintenance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070050" ; a owl:Class ; rdfs:label "neuron cellular homeostasis" ; rdfs:subClassOf obo:GO_0019725, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000540 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0019725 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0070051 obo:IAO_0000115 "Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0070051" ; a owl:Class ; rdfs:label "fibrinogen binding" ; rdfs:subClassOf obo:GO_0044877, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005577 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0005577 ] ) ] . obo:GO_0070062 obo:IAO_0000115 "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm." ; oboInOwl:hasExactSynonym "exosome", "extracellular vesicular exosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0070062" ; a owl:Class ; rdfs:label "extracellular exosome" ; rdfs:subClassOf obo:GO_1903561, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005615 ] . obo:GO_0070091 obo:IAO_0000115 "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070091" ; a owl:Class ; rdfs:label "glucagon secretion" ; rdfs:subClassOf obo:GO_0030072, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_5391 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_5391 ] ) ] . obo:GO_0070092 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of glucagon." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070092" ; a owl:Class ; rdfs:label "regulation of glucagon secretion" ; rdfs:subClassOf obo:GO_0090276, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070091 ] ) ] . obo:GO_0070093 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon." ; oboInOwl:hasExactSynonym "down regulation of glucagon secretion", "down-regulation of glucagon secretion", "downregulation of glucagon secretion" ; oboInOwl:hasNarrowSynonym "inhibition of glucagon secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070093" ; a owl:Class ; rdfs:label "negative regulation of glucagon secretion" ; rdfs:subClassOf obo:GO_0070092, obo:GO_0090278, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070091 ] ) ] . obo:GO_0070094 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon." ; oboInOwl:hasExactSynonym "up regulation of glucagon secretion", "up-regulation of glucagon secretion", "upregulation of glucagon secretion" ; oboInOwl:hasNarrowSynonym "activation of glucagon secretion", "stimulation of glucagon secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070094" ; a owl:Class ; rdfs:label "positive regulation of glucagon secretion" ; rdfs:subClassOf obo:GO_0070092, obo:GO_0090277, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070091 ] ) ] . obo:GO_0070125 obo:IAO_0000115 "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion." ; oboInOwl:hasExactSynonym "mitochondrial translation elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070125" ; a owl:Class ; rdfs:label "mitochondrial translational elongation" ; rdfs:subClassOf obo:GO_0006414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032543 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006414 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0070129 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ; oboInOwl:hasExactSynonym "regulation of mitochondrial protein anabolism", "regulation of mitochondrial protein biosynthesis", "regulation of mitochondrial protein formation", "regulation of mitochondrial protein synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070129" ; a owl:Class ; rdfs:label "regulation of mitochondrial translation" ; rdfs:subClassOf obo:GO_0006417, obo:GO_0062125, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032543 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032543 ] ) ] . obo:GO_0070130 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ; oboInOwl:hasExactSynonym "negative regulation of mitochondrial protein anabolism", "negative regulation of mitochondrial protein biosynthesis", "negative regulation of mitochondrial protein formation", "negative regulation of mitochondrial protein synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070130" ; a owl:Class ; rdfs:label "negative regulation of mitochondrial translation" ; rdfs:subClassOf obo:GO_0017148, obo:GO_0070129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032543 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032543 ] ) ] . obo:GO_0070131 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ; oboInOwl:hasExactSynonym "positive regulation of mitochondrial protein anabolism", "positive regulation of mitochondrial protein biosynthesis", "positive regulation of mitochondrial protein formation", "positive regulation of mitochondrial protein synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070131" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial translation" ; rdfs:subClassOf obo:GO_0045727, obo:GO_0070129, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032543 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032543 ] ) ] . obo:GO_0070160 obo:IAO_0000115 "A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." ; oboInOwl:hasDbXref "Wikipedia:Tight_junction" ; oboInOwl:hasExactSynonym "occluding cell junction", "occluding junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0070160" ; a owl:Class ; rdfs:label "tight junction" ; rdfs:subClassOf obo:GO_0005911 . obo:GO_0070161 obo:IAO_0000115 "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." ; oboInOwl:hasExactSynonym "anchoring cell junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0070161" ; a owl:Class ; rdfs:label "anchoring junction" ; rdfs:subClassOf obo:GO_0030054 . obo:GO_0070192 obo:IAO_0000115 "A process of chromosome organization that is involved in a meiotic cell cycle." ; oboInOwl:hasExactSynonym "chromosome organisation involved in meiosis", "meiotic chromosome organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070192" ; a owl:Class ; rdfs:label "chromosome organization involved in meiotic cell cycle" ; rdfs:subClassOf obo:GO_0051276, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051276 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0070199 obo:IAO_0000115 "The directed movement of a protein to a specific location on a chromosome." ; oboInOwl:hasExactSynonym "establishment of protein localisation to chromosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070199" ; a owl:Class ; rdfs:label "establishment of protein localization to chromosome" ; rdfs:subClassOf obo:GO_0034502, obo:GO_0072594 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045184 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005694 ] ) ] . obo:GO_0070201 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." ; oboInOwl:hasExactSynonym "regulation of establishment of protein localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070201" ; a owl:Class ; rdfs:label "regulation of establishment of protein localization" ; rdfs:subClassOf obo:GO_0032880, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045184 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045184 ] ) ] . obo:GO_0070202 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome." ; oboInOwl:hasExactSynonym "regulation of establishment of protein localisation to chromosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070202" ; a owl:Class ; rdfs:label "regulation of establishment of protein localization to chromosome" ; rdfs:subClassOf obo:GO_0070201, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070199 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070199 ] ) ] . obo:GO_0070227 obo:IAO_0000115 "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin." ; oboInOwl:hasNarrowSynonym "lymphocyte apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070227" ; a owl:Class ; rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542)." ; rdfs:label "lymphocyte apoptotic process" ; rdfs:subClassOf obo:GO_0071887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000542 ] ) ] . obo:GO_0070228 obo:IAO_0000115 "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process." ; oboInOwl:hasNarrowSynonym "regulation of lymphocyte apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070228" ; a owl:Class ; rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542)." ; rdfs:label "regulation of lymphocyte apoptotic process" ; rdfs:subClassOf obo:GO_2000106, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070227 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070227 ] ) ] . obo:GO_0070229 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process." ; oboInOwl:hasExactSynonym "down regulation of lymphocyte apoptosis", "down-regulation of lymphocyte apoptosis", "downregulation of lymphocyte apoptosis" ; oboInOwl:hasNarrowSynonym "inhibition of lymphocyte apoptosis", "negative regulation of lymphocyte apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070229" ; a owl:Class ; rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542)." ; rdfs:label "negative regulation of lymphocyte apoptotic process" ; rdfs:subClassOf obo:GO_0070228, obo:GO_2000107, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070227 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070227 ] ) ] . obo:GO_0070230 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process." ; oboInOwl:hasExactSynonym "up regulation of lymphocyte apoptosis", "up-regulation of lymphocyte apoptosis", "upregulation of lymphocyte apoptosis" ; oboInOwl:hasNarrowSynonym "activation of lymphocyte apoptosis", "positive regulation of lymphocyte apoptosis", "stimulation of lymphocyte apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070230" ; a owl:Class ; rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542)." ; rdfs:label "positive regulation of lymphocyte apoptotic process" ; rdfs:subClassOf obo:GO_0070228, obo:GO_2000108, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070227 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070227 ] ) ] . obo:GO_0070231 obo:IAO_0000115 "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex." ; oboInOwl:hasExactSynonym "T lymphocyte apoptosis", "T-cell apoptosis", "T-lymphocyte apoptosis", "programmed cell death of T cells by apoptosis" ; oboInOwl:hasNarrowSynonym "T cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070231" ; a owl:Class ; rdfs:label "T cell apoptotic process" ; rdfs:subClassOf obo:GO_0070227, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0070232 obo:IAO_0000115 "Any process that modulates the occurrence or rate of T cell death by apoptotic process." ; oboInOwl:hasExactSynonym "regulation of T lymphocyte apoptosis", "regulation of T-cell apoptosis", "regulation of T-lymphocyte apoptosis", "regulation of programmed cell death of T cells by apoptosis" ; oboInOwl:hasNarrowSynonym "regulation of T cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070232" ; a owl:Class ; rdfs:label "regulation of T cell apoptotic process" ; rdfs:subClassOf obo:GO_0070228, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070231 ] ) ] . obo:GO_0070233 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process." ; oboInOwl:hasExactSynonym "down regulation of T cell apoptosis", "down-regulation of T cell apoptosis", "downregulation of T cell apoptosis", "negative regulation of T lymphocyte apoptosis", "negative regulation of T-cell apoptosis", "negative regulation of T-lymphocyte apoptosis", "negative regulation of programmed cell death of T cells by apoptosis" ; oboInOwl:hasNarrowSynonym "inhibition of T cell apoptosis", "negative regulation of T cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070233" ; a owl:Class ; rdfs:label "negative regulation of T cell apoptotic process" ; rdfs:subClassOf obo:GO_0070229, obo:GO_0070232, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070231 ] ) ] . obo:GO_0070234 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process." ; oboInOwl:hasExactSynonym "positive regulation of T lymphocyte apoptosis", "positive regulation of T-cell apoptosis", "positive regulation of T-lymphocyte apoptosis", "positive regulation of programmed cell death of T cells by apoptosis", "up regulation of T cell apoptosis", "up-regulation of T cell apoptosis", "upregulation of T cell apoptosis" ; oboInOwl:hasNarrowSynonym "activation of T cell apoptosis", "positive regulation of T cell apoptosis", "stimulation of T cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070234" ; a owl:Class ; rdfs:label "positive regulation of T cell apoptotic process" ; rdfs:subClassOf obo:GO_0070230, obo:GO_0070232, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070231 ] ) ] . obo:GO_0070253 obo:IAO_0000115 "The regulated release of somatostatin from secretory granules in the D cells of the pancreas." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070253" ; a owl:Class ; rdfs:label "somatostatin secretion" ; rdfs:subClassOf obo:GO_0030072, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64628 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_64628 ] ) ] . obo:GO_0070254 obo:IAO_0000115 "The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function." ; oboInOwl:hasExactSynonym "mucus production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070254" ; a owl:Class ; rdfs:label "mucus secretion" ; rdfs:subClassOf obo:GO_0007589, obo:GO_0032941, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:UBERON_0000912 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:UBERON_0000912 ] ) ] . obo:GO_0070255 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." ; oboInOwl:hasExactSynonym "regulation of mucus production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070255" ; a owl:Class ; rdfs:label "regulation of mucus secretion" ; rdfs:subClassOf obo:GO_0050878, obo:GO_0051046, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070254 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070254 ] ) ] . obo:GO_0070256 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." ; oboInOwl:hasExactSynonym "negative regulation of mucus production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070256" ; a owl:Class ; rdfs:label "negative regulation of mucus secretion" ; rdfs:subClassOf obo:GO_0051048, obo:GO_0051241, obo:GO_0070255, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070254 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070254 ] ) ] . obo:GO_0070257 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue." ; oboInOwl:hasExactSynonym "positive regulation of mucus production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070257" ; a owl:Class ; rdfs:label "positive regulation of mucus secretion" ; rdfs:subClassOf obo:GO_0051047, obo:GO_0051240, obo:GO_0070255, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070254 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070254 ] ) ] . obo:GO_0070265 obo:IAO_0000115 "A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues." ; oboInOwl:hasBroadSynonym "necrosis" ; oboInOwl:hasExactSynonym "cellular necrosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070265" ; a owl:Class ; rdfs:comment "Note that the word necrosis has been widely used in earlier literature to describe forms of cell death which are now known by more precise terms, such as apoptosis. Necrosis can occur in a regulated fashion, involving a precise sequence of signals; in this case, consider annotating to GO:0097300 'programmed necrotic cell death' or to its more specific child GO:0070266 'necroptotic process'." ; rdfs:label "necrotic cell death" ; rdfs:subClassOf obo:GO_0008219 . obo:GO_0070285 obo:IAO_0000115 "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070285" ; a owl:Class ; rdfs:label "pigment cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050931 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000147 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000147 ] ) ] . obo:GO_0070341 obo:IAO_0000115 "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat." ; oboInOwl:hasExactSynonym "adipocyte proliferation", "adipose cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070341" ; a owl:Class ; rdfs:label "fat cell proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000136 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000136 ] ) ] . obo:GO_0070344 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of fat cell proliferation." ; oboInOwl:hasExactSynonym "regulation of adipocyte proliferation", "regulation of adipose cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070344" ; a owl:Class ; rdfs:label "regulation of fat cell proliferation" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070341 ] ) ] . obo:GO_0070345 obo:IAO_0000115 "Any process that stops or decreases the rate or extent of fat cell proliferation." ; oboInOwl:hasExactSynonym "down regulation of fat cell proliferation", "down-regulation of fat cell proliferation", "downregulation of fat cell proliferation", "negative regulation of adipocyte proliferation", "negative regulation of adipose cell proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of fat cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070345" ; a owl:Class ; rdfs:label "negative regulation of fat cell proliferation" ; rdfs:subClassOf obo:GO_0008285, obo:GO_0070344, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070341 ] ) ] . obo:GO_0070346 obo:IAO_0000115 "Any process that activates or increases the rate or extent of fat cell proliferation." ; oboInOwl:hasExactSynonym "positive regulation of adipocyte proliferation", "positive regulation of adipose cell proliferation", "up regulation of fat cell proliferation", "up-regulation of fat cell proliferation", "upregulation of fat cell proliferation" ; oboInOwl:hasNarrowSynonym "activation of fat cell proliferation", "stimulation of fat cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070346" ; a owl:Class ; rdfs:label "positive regulation of fat cell proliferation" ; rdfs:subClassOf obo:GO_0008284, obo:GO_0070344, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070341 ] ) ] . obo:GO_0070365 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver." ; oboInOwl:hasExactSynonym "liver cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070365" ; a owl:Class ; rdfs:label "hepatocyte differentiation" ; rdfs:subClassOf obo:GO_0030855, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001889 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000182 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000182 ] ) ] . obo:GO_0070366 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of hepatocyte differentiation." ; oboInOwl:hasExactSynonym "regulation of liver cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070366" ; a owl:Class ; rdfs:label "regulation of hepatocyte differentiation" ; rdfs:subClassOf obo:GO_0030856, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070365 ] ) ] . obo:GO_0070367 obo:IAO_0000115 "Any process that stops or decreases the rate or extent of hepatocyte differentiation." ; oboInOwl:hasExactSynonym "down regulation of hepatocyte differentiation", "down-regulation of hepatocyte differentiation", "downregulation of hepatocyte differentiation", "negative regulation of liver cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of hepatocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070367" ; a owl:Class ; rdfs:label "negative regulation of hepatocyte differentiation" ; rdfs:subClassOf obo:GO_0030857, obo:GO_0051241, obo:GO_0070366, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070365 ] ) ] . obo:GO_0070368 obo:IAO_0000115 "Any process that activates or increases the rate or extent of hepatocyte differentiation." ; oboInOwl:hasExactSynonym "positive regulation of liver cell differentiation", "up regulation of hepatocyte differentiation", "up-regulation of hepatocyte differentiation", "upregulation of hepatocyte differentiation" ; oboInOwl:hasNarrowSynonym "activation of hepatocyte differentiation", "stimulation of hepatocyte differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070368" ; a owl:Class ; rdfs:label "positive regulation of hepatocyte differentiation" ; rdfs:subClassOf obo:GO_0030858, obo:GO_0051240, obo:GO_0070366, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070365 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070365 ] ) ] . obo:GO_0070382 obo:IAO_0000115 "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." ; oboInOwl:hasExactSynonym "exocytic constitutive secretory pathway transport vesicle", "exocytotic vesicle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0070382" ; a owl:Class ; rdfs:label "exocytic vesicle" ; rdfs:subClassOf obo:GO_0030133, obo:GO_0099503 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030133 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0099500 ] ) ] . obo:GO_0070405 obo:IAO_0000115 "Binding to ammonium ions (NH4+)." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "ammonium binding" ; oboInOwl:id "GO:0070405" ; a owl:Class ; rdfs:label "ammonium ion binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_28938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_28938 ] ) ] . obo:GO_0070482 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070482" ; a owl:Class ; rdfs:label "response to oxygen levels" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0070507 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." ; oboInOwl:hasExactSynonym "regulation of microtubule cytoskeleton organisation", "regulation of microtubule dynamics" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070507" ; a owl:Class ; rdfs:label "regulation of microtubule cytoskeleton organization" ; rdfs:subClassOf obo:GO_0032886, obo:GO_0051493, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000226 ] ) ] . obo:GO_0070585 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within the mitochondrion." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-04-24T02:31:18Z" ; oboInOwl:hasExactSynonym "protein localisation in mitochondrion", "protein localization in mitochondrion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070585" ; a owl:Class ; rdfs:label "protein localization to mitochondrion" ; rdfs:subClassOf obo:GO_0033365 . obo:GO_0070588 obo:IAO_0000115 "A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-04-28T10:44:09Z" ; oboInOwl:hasExactSynonym "calcium ion membrane transport", "transmembrane calcium transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070588" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "calcium ion transmembrane transport" ; rdfs:subClassOf obo:GO_0006816, obo:GO_0098655, obo:GO_0098662 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055085 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_29108 ] ) ] . obo:GO_0070633 obo:IAO_0000115 "The directed movement of a substance from one side of an epithelium to the other." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-05-06T03:31:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070633" ; a owl:Class ; rdfs:label "transepithelial transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:UBERON_0000483 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:UBERON_0000483 ] ) ] . obo:GO_0070634 obo:IAO_0000115 "The directed movement of ammonium ions from one side of an epithelium to the other." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-05-06T03:34:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070634" ; a owl:Class ; rdfs:label "transepithelial ammonium transport" ; rdfs:subClassOf obo:GO_0070633, obo:GO_0071705, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_28938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070633 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_28938 ] ) ] . obo:GO_0070661 obo:IAO_0000115 "The expansion of a leukocyte population by cell division." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-05-28T05:25:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070661" ; a owl:Class ; rdfs:label "leukocyte proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000738 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0070663 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of leukocyte proliferation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-05-28T05:30:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070663" ; a owl:Class ; rdfs:label "regulation of leukocyte proliferation" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070661 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070661 ] ) ] . obo:GO_0070664 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-05-28T05:34:50Z" ; oboInOwl:hasExactSynonym "down regulation of leukocyte proliferation", "down-regulation of leukocyte proliferation", "downregulation of leukocyte proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of leukocyte proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070664" ; a owl:Class ; rdfs:label "negative regulation of leukocyte proliferation" ; rdfs:subClassOf obo:GO_0008285, obo:GO_0070663, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070661 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070661 ] ) ] . obo:GO_0070665 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-05-28T05:36:46Z" ; oboInOwl:hasExactSynonym "up regulation of leukocyte proliferation", "up-regulation of leukocyte proliferation", "upregulation of leukocyte proliferation" ; oboInOwl:hasNarrowSynonym "activation of leukocyte proliferation", "stimulation of leukocyte proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070665" ; a owl:Class ; rdfs:label "positive regulation of leukocyte proliferation" ; rdfs:subClassOf obo:GO_0008284, obo:GO_0070663, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070661 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070661 ] ) ] . obo:GO_0070727 obo:IAO_0000115 "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-06-16T04:08:29Z" ; oboInOwl:hasExactSynonym "cellular macromolecule localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070727" ; a owl:Class ; rdfs:label "cellular macromolecule localization" ; rdfs:subClassOf obo:GO_0033036, obo:GO_0051641 . obo:GO_0070830 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-07-23T04:32:38Z" ; oboInOwl:hasExactSynonym "tight junction formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070830" ; a owl:Class ; rdfs:label "bicellular tight junction assembly" ; rdfs:subClassOf obo:GO_0120192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043297 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005923 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005923 ] ) ] . obo:GO_0070831 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-07-23T05:01:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070831" ; a owl:Class ; rdfs:comment "Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer." ; rdfs:label "basement membrane assembly" ; rdfs:subClassOf obo:GO_0071711, obo:GO_0085029, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005604 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0005604 ] ) ] . obo:GO_0070851 obo:IAO_0000115 "Binding to a growth factor receptor." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-08-07T11:23:02Z" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0070851" ; a owl:Class ; rdfs:label "growth factor receptor binding" ; rdfs:subClassOf obo:GO_0005102 . obo:GO_0070857 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-08-14T03:09:02Z" ; oboInOwl:hasExactSynonym "regulation of bile acid anabolism", "regulation of bile acid biosynthesis", "regulation of bile acid formation", "regulation of bile acid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070857" ; a owl:Class ; rdfs:label "regulation of bile acid biosynthetic process" ; rdfs:subClassOf obo:GO_0010565, obo:GO_0031326, obo:GO_0050810, obo:GO_1904251, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006699 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006699 ] ) ] . obo:GO_0070858 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-08-14T03:16:40Z" ; oboInOwl:hasExactSynonym "down regulation of bile acid biosynthetic process", "down-regulation of bile acid biosynthetic process", "downregulation of bile acid biosynthetic process", "negative regulation of bile acid anabolism", "negative regulation of bile acid biosynthesis", "negative regulation of bile acid formation", "negative regulation of bile acid synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of bile acid biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070858" ; a owl:Class ; rdfs:label "negative regulation of bile acid biosynthetic process" ; rdfs:subClassOf obo:GO_0010894, obo:GO_0031327, obo:GO_0070857, obo:GO_1904252, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006699 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006699 ] ) ] . obo:GO_0070859 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-08-14T03:22:58Z" ; oboInOwl:hasExactSynonym "positive regulation of bile acid anabolism", "positive regulation of bile acid biosynthesis", "positive regulation of bile acid formation", "positive regulation of bile acid synthesis", "up regulation of bile acid biosynthetic process", "up-regulation of bile acid biosynthetic process", "upregulation of bile acid biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of bile acid biosynthetic process", "stimulation of bile acid biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070859" ; a owl:Class ; rdfs:label "positive regulation of bile acid biosynthetic process" ; rdfs:subClassOf obo:GO_0010893, obo:GO_0031328, obo:GO_0070857, obo:GO_1904253, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006699 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006699 ] ) ] . obo:GO_0070873 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-08-20T02:44:53Z" ; oboInOwl:hasExactSynonym "regulation of glycogen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070873" ; a owl:Class ; rdfs:label "regulation of glycogen metabolic process" ; rdfs:subClassOf obo:GO_0032881, obo:GO_0043467, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005977 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005977 ] ) ] . obo:GO_0070874 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-08-20T02:50:41Z" ; oboInOwl:hasExactSynonym "negative regulation of glycogen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070874" ; a owl:Class ; rdfs:label "negative regulation of glycogen metabolic process" ; rdfs:subClassOf obo:GO_0010605, obo:GO_0031324, obo:GO_0045912, obo:GO_0070873, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005977 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005977 ] ) ] . obo:GO_0070875 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-08-20T02:53:55Z" ; oboInOwl:hasExactSynonym "positive regulation of glycogen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070875" ; a owl:Class ; rdfs:label "positive regulation of glycogen metabolic process" ; rdfs:subClassOf obo:GO_0010604, obo:GO_0010907, obo:GO_0031325, obo:GO_0070873, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005977 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005977 ] ) ] . obo:GO_0070887 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-08-27T04:41:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070887" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to chemical stimulus" ; rdfs:subClassOf obo:GO_0042221, obo:GO_0051716 . obo:GO_0070925 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-09-15T03:00:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070925" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "organelle assembly" ; rdfs:subClassOf obo:GO_0006996, obo:GO_0022607, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0070972 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-10-02T12:43:34Z" ; oboInOwl:hasExactSynonym "protein localisation in endoplasmic reticulum", "protein localization in ER", "protein localization in endoplasmic reticulum" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070972" ; a owl:Class ; rdfs:label "protein localization to endoplasmic reticulum" ; rdfs:subClassOf obo:GO_0033365 . obo:GO_0070977 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-10-05T04:35:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070977" ; a owl:Class ; rdfs:label "bone maturation" ; rdfs:subClassOf obo:GO_0048799, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060348 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001474 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0001474 ] ) ] . obo:GO_0070997 obo:IAO_0000115 "The process of cell death in a neuron." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-11-03T02:37:17Z" ; oboInOwl:hasExactSynonym "neuron cell death", "neuronal cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070997" ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. The only exception should be when experimental data (e.g., staining with trypan blue or propidium iodide or use of neuron-specific markers) show that neuron death has occurred, but fail to provide details on death modality (accidental versus programmed). When information is provided on the neuron death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'), and the cell type captured as an annotation extension; or the term GO:0051402 'neuron apoptotic process' may be considered, if appropriate." ; rdfs:label "neuron death" ; rdfs:subClassOf obo:GO_0008219, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000540 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008219 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000540 ] ) ] . obo:GO_0071025 obo:IAO_0000115 "A process that identifies and degrades defective or aberrant RNAs." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2009-07-28T03:10:28Z" ; oboInOwl:hasExactSynonym "RNA quality control", "aberrant RNA catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071025" ; a owl:Class ; rdfs:label "RNA surveillance" ; rdfs:subClassOf obo:GO_0006401 . obo:GO_0071026 obo:IAO_0000115 "The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2009-07-28T03:14:03Z" ; oboInOwl:hasExactSynonym "cytoplasmic RNA quality control", "cytoplasmic aberrant RNA catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071026" ; a owl:Class ; rdfs:label "cytoplasmic RNA surveillance" ; rdfs:subClassOf obo:GO_0071025, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0071027 obo:IAO_0000115 "A process that identifies and degrades defective or aberrant RNAs within the nucleus." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2009-07-28T03:45:02Z" ; oboInOwl:hasExactSynonym "nuclear RNA quality control", "nuclear aberrant RNA catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071027" ; a owl:Class ; rdfs:label "nuclear RNA surveillance" ; rdfs:subClassOf obo:GO_0071025, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0071028 obo:IAO_0000115 "A process that identifies and degrades defective or aberrant mRNAs within the nucleus." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22342"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2009-07-28T04:14:29Z" ; oboInOwl:hasAlternativeId "GO:0071033", "GO:0071048", "GO:0071049" ; oboInOwl:hasExactSynonym "nuclear aberrant mRNA catabolic process", "nuclear mRNA quality control" ; oboInOwl:hasNarrowSynonym "nuclear retention of pre-mRNA at the site of transcription", "nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription", "nuclear retention of unspliced pre-mRNA at the site of transcription" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071028" ; a owl:Class ; rdfs:label "nuclear mRNA surveillance" ; rdfs:subClassOf obo:GO_0000956, obo:GO_0071027 . obo:GO_0071166 obo:IAO_0000115 "Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-11-19T04:46:05Z" ; oboInOwl:hasExactSynonym "RNP localization", "cellular ribonucleoprotein complex localization", "establishment and maintenance of ribonucleoprotein complex localization", "ribonucleoprotein complex localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071166" ; a owl:Class ; rdfs:label "ribonucleoprotein complex localization" ; rdfs:subClassOf obo:GO_0051641 . obo:GO_0071168 obo:IAO_0000115 "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-11-20T11:51:20Z" ; oboInOwl:hasExactSynonym "protein localisation to chromatin" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071168" ; a owl:Class ; rdfs:label "protein localization to chromatin" ; rdfs:subClassOf obo:GO_0034502, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0000785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0000785 ] ) ] . obo:GO_0071169 obo:IAO_0000115 "The directed movement of a protein to a part of a chromosome that is organized into chromatin." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-11-20T11:52:43Z" ; oboInOwl:hasExactSynonym "establishment of protein localisation to chromatin" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071169" ; a owl:Class ; rdfs:label "establishment of protein localization to chromatin" ; rdfs:subClassOf obo:GO_0070199, obo:GO_0071168 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045184 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0000785 ] ) ] . obo:GO_0071173 obo:IAO_0000115 "A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-11-23T12:36:57Z" ; oboInOwl:hasAlternativeId "GO:0072486" ; oboInOwl:hasBroadSynonym "SAC" ; oboInOwl:hasExactSynonym "signal transduction involved in spindle assembly checkpoint", "spindle assembly checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071173" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle assembly checkpoint (mitotic or meiotic)." ; rdfs:label "spindle assembly checkpoint signaling" ; rdfs:subClassOf obo:GO_0031577 . obo:GO_0071174 obo:IAO_0000115 "A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-11-23T12:41:36Z" ; oboInOwl:hasAlternativeId "GO:0072477" ; oboInOwl:hasExactSynonym "mitotic cell cycle spindle checkpoint", "mitotic spindle checkpoint", "signal transduction involved in mitotic cell cycle spindle checkpoint", "signal transduction involved in mitotic spindle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "topo II checkpoint", "topoisomerase II checkpoint" ; oboInOwl:id "GO:0071174" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation checkpoints)." ; rdfs:label "mitotic spindle checkpoint signaling" ; rdfs:subClassOf obo:GO_0007093, obo:GO_0031577 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031577 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0071214 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-03T01:02:11Z" ; oboInOwl:hasNarrowSynonym "cellular response to abiotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071214" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to abiotic stimulus" ; rdfs:subClassOf obo:GO_0009628, obo:GO_0104004 . obo:GO_0071216 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-03T01:09:08Z" ; oboInOwl:hasNarrowSynonym "cellular response to biotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071216" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to biotic stimulus" ; rdfs:subClassOf obo:GO_0009607, obo:GO_0051716 . obo:GO_0071230 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-03T02:08:11Z" ; oboInOwl:hasExactSynonym "cellular response to amino acid" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071230" ; a owl:Class ; rdfs:label "cellular response to amino acid stimulus" ; rdfs:subClassOf obo:GO_0043200, obo:GO_0071417, obo:GO_1901701 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33709 ] ) ] . obo:GO_0071241 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-03T02:35:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071241" ; a owl:Class ; rdfs:label "cellular response to inorganic substance" ; rdfs:subClassOf obo:GO_0010035, obo:GO_0070887 . obo:GO_0071242 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-03T02:39:40Z" ; oboInOwl:hasAlternativeId "GO:1903718" ; oboInOwl:hasExactSynonym "cellular response to ammonia" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071242" ; a owl:Class ; rdfs:label "cellular response to ammonium ion" ; rdfs:subClassOf obo:GO_0060359, obo:GO_1901699 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_28938 ] ) ] . obo:GO_0071248 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-03T02:46:31Z" ; oboInOwl:hasExactSynonym "cellular response to metal" ; oboInOwl:hasNarrowSynonym "cellular response to heavy metal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071248" ; a owl:Class ; rdfs:label "cellular response to metal ion" ; rdfs:subClassOf obo:GO_0010038, obo:GO_0071241 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_25213 ] ) ] . obo:GO_0071310 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-10T04:46:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071310" ; a owl:Class ; rdfs:label "cellular response to organic substance" ; rdfs:subClassOf obo:GO_0010033, obo:GO_0070887 . obo:GO_0071311 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-10T04:48:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071311" ; a owl:Class ; rdfs:label "cellular response to acetate" ; rdfs:subClassOf obo:GO_0010034, obo:GO_0071310, obo:GO_1901701 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_30089 ] ) ] . obo:GO_0071312 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-10T04:50:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071312" ; a owl:Class ; rdfs:label "cellular response to alkaloid" ; rdfs:subClassOf obo:GO_0043279, obo:GO_0071417 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_22315 ] ) ] . obo:GO_0071322 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-10T05:13:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071322" ; a owl:Class ; rdfs:label "cellular response to carbohydrate stimulus" ; rdfs:subClassOf obo:GO_0009743, obo:GO_0071310, obo:GO_1901701 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_16646 ] ) ] . obo:GO_0071326 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-10T05:27:18Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071326" ; a owl:Class ; rdfs:label "cellular response to monosaccharide stimulus" ; rdfs:subClassOf obo:GO_0034284, obo:GO_0071322 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35381 ] ) ] . obo:GO_0071331 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-10T05:37:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071331" ; a owl:Class ; rdfs:label "cellular response to hexose stimulus" ; rdfs:subClassOf obo:GO_0009746, obo:GO_0071326 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18133 ] ) ] . obo:GO_0071333 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-10T05:38:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071333" ; a owl:Class ; rdfs:label "cellular response to glucose stimulus" ; rdfs:subClassOf obo:GO_0001678, obo:GO_0009749, obo:GO_0071331 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_17234 ] ) ] . obo:GO_0071375 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-11T03:24:18Z" ; oboInOwl:hasExactSynonym "cellular response to polypeptide hormone stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071375" ; a owl:Class ; rdfs:label "cellular response to peptide hormone stimulus" ; rdfs:subClassOf obo:GO_0043434, obo:GO_1901653 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_25905 ] ) ] . obo:GO_0071377 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-11T03:25:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071377" ; a owl:Class ; rdfs:label "cellular response to glucagon stimulus" ; rdfs:subClassOf obo:GO_0033762, obo:GO_0071375 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_5391 ] ) ] . obo:GO_0071383 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-11T03:49:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071383" ; a owl:Class ; rdfs:label "cellular response to steroid hormone stimulus" ; rdfs:subClassOf obo:GO_0048545, obo:GO_0071396, obo:GO_0071407 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_26764 ] ) ] . obo:GO_0071396 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-11T04:37:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071396" ; a owl:Class ; rdfs:label "cellular response to lipid" ; rdfs:subClassOf obo:GO_0033993, obo:GO_0071310 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0071407 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-14T02:55:58Z" ; oboInOwl:hasExactSynonym "cellular response to organic cyclic substance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071407" ; a owl:Class ; rdfs:label "cellular response to organic cyclic compound" ; rdfs:subClassOf obo:GO_0014070, obo:GO_0071310 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33832 ] ) ] . obo:GO_0071417 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-14T04:07:27Z" ; oboInOwl:hasExactSynonym "cellular response to organic nitrogen" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071417" ; a owl:Class ; rdfs:label "cellular response to organonitrogen compound" ; rdfs:subClassOf obo:GO_0010243, obo:GO_0071310, obo:GO_0071495, obo:GO_1901699 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_35352 ] ) ] . obo:GO_0071418 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-14T04:08:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071418" ; a owl:Class ; rdfs:label "cellular response to amine stimulus" ; rdfs:subClassOf obo:GO_0014075, obo:GO_0071417 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_32952 ] ) ] . obo:GO_0071425 obo:IAO_0000115 "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-16T10:22:52Z" ; oboInOwl:hasExactSynonym "hemopoietic stem cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071425" ; a owl:Class ; rdfs:label "hematopoietic stem cell proliferation" ; rdfs:subClassOf obo:GO_0072089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030097 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000037 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000037 ] ) ] . obo:GO_0071470 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T11:45:33Z" ; oboInOwl:hasExactSynonym "cellular osmotic response", "cellular osmotic stress response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071470" ; a owl:Class ; rdfs:label "cellular response to osmotic stress" ; rdfs:subClassOf obo:GO_0006970, obo:GO_0062197, obo:GO_0071214 . obo:GO_0071478 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T01:59:37Z" ; oboInOwl:hasExactSynonym "cellular response to electromagnetic radiation stimulus", "cellular response to radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071478" ; a owl:Class ; rdfs:comment "Note that 'radiation' refers to electromagnetic radiation of any wavelength." ; rdfs:label "cellular response to radiation" ; rdfs:subClassOf obo:GO_0009314, obo:GO_0071214 . obo:GO_0071479 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T02:00:31Z" ; oboInOwl:hasExactSynonym "cellular response to ionising radiation", "cellular response to ionizing radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071479" ; a owl:Class ; rdfs:label "cellular response to ionizing radiation" ; rdfs:subClassOf obo:GO_0010212, obo:GO_0071478 . obo:GO_0071480 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T02:00:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular response to gamma ray", "cellular response to gamma-ray photon" ; oboInOwl:id "GO:0071480" ; a owl:Class ; rdfs:label "cellular response to gamma radiation" ; rdfs:subClassOf obo:GO_0010332, obo:GO_0071479 . obo:GO_0071482 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T02:03:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071482" ; a owl:Class ; rdfs:label "cellular response to light stimulus" ; rdfs:subClassOf obo:GO_0009416, obo:GO_0071478 . obo:GO_0071495 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T02:25:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071495" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to endogenous stimulus" ; rdfs:subClassOf obo:GO_0009719 . obo:GO_0071542 obo:IAO_0000115 "The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-12T02:28:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071542" ; a owl:Class ; rdfs:label "dopaminergic neuron differentiation" ; rdfs:subClassOf obo:GO_0030182, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000700 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000700 ] ) ] . obo:GO_0071626 obo:IAO_0000115 "The process of biting and mashing food with the teeth prior to swallowing." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-10T11:19:48Z" ; oboInOwl:hasExactSynonym "chewing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071626" ; a owl:Class ; rdfs:label "mastication" ; rdfs:subClassOf obo:GO_0022600 . obo:GO_0071670 obo:IAO_0000115 "The directed movement of a smooth muscle cell in response to an external stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-16T01:32:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071670" ; a owl:Class ; rdfs:label "smooth muscle cell chemotaxis" ; rdfs:subClassOf obo:GO_0014909, obo:GO_0060326 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006935 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000192 ] ) ] . obo:GO_0071671 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-16T01:42:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071671" ; a owl:Class ; rdfs:label "regulation of smooth muscle cell chemotaxis" ; rdfs:subClassOf obo:GO_0014910, obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071670 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071670 ] ) ] . obo:GO_0071672 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-16T01:44:28Z" ; oboInOwl:hasExactSynonym "down regulation of smooth muscle cell chemotaxis", "down-regulation of smooth muscle cell chemotaxis", "downregulation of smooth muscle cell chemotaxis" ; oboInOwl:hasNarrowSynonym "inhibition of smooth muscle cell chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071672" ; a owl:Class ; rdfs:label "negative regulation of smooth muscle cell chemotaxis" ; rdfs:subClassOf obo:GO_0014912, obo:GO_0050922, obo:GO_0071671, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071670 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071670 ] ) ] . obo:GO_0071673 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-16T01:48:14Z" ; oboInOwl:hasExactSynonym "up regulation of smooth muscle cell chemotaxis", "up-regulation of smooth muscle cell chemotaxis", "upregulation of smooth muscle cell chemotaxis" ; oboInOwl:hasNarrowSynonym "activation of smooth muscle cell chemotaxis", "stimulation of smooth muscle cell chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071673" ; a owl:Class ; rdfs:label "positive regulation of smooth muscle cell chemotaxis" ; rdfs:subClassOf obo:GO_0014911, obo:GO_0050921, obo:GO_0071671, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071670 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071670 ] ) ] . obo:GO_0071674 obo:IAO_0000115 "The movement of a mononuclear cell within or between different tissues and organs of the body." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-16T02:11:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071674" ; a owl:Class ; rdfs:label "mononuclear cell migration" ; rdfs:subClassOf obo:GO_0050900, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000842 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000842 ] ) ] . obo:GO_0071675 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-16T02:11:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071675" ; a owl:Class ; rdfs:label "regulation of mononuclear cell migration" ; rdfs:subClassOf obo:GO_0002685, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071674 ] ) ] . obo:GO_0071676 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-16T02:13:55Z" ; oboInOwl:hasExactSynonym "down regulation of mononuclear cell migration", "down-regulation of mononuclear cell migration", "downregulation of mononuclear cell migration" ; oboInOwl:hasNarrowSynonym "inhibition of mononuclear cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071676" ; a owl:Class ; rdfs:label "negative regulation of mononuclear cell migration" ; rdfs:subClassOf obo:GO_0002686, obo:GO_0071675, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071674 ] ) ] . obo:GO_0071677 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-16T02:15:29Z" ; oboInOwl:hasExactSynonym "up regulation of mononuclear cell migration", "up-regulation of mononuclear cell migration", "upregulation of mononuclear cell migration" ; oboInOwl:hasNarrowSynonym "activation of mononuclear cell migration", "stimulation of mononuclear cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071677" ; a owl:Class ; rdfs:label "positive regulation of mononuclear cell migration" ; rdfs:subClassOf obo:GO_0002687, obo:GO_0071675, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071674 ] ) ] . obo:GO_0071682 obo:IAO_0000115 "The volume enclosed by the membrane of an endocytic vesicle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-18T04:21:53Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0071682" ; a owl:Class ; rdfs:label "endocytic vesicle lumen" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031974 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030139 ] ) ] . obo:GO_0071684 obo:IAO_0000115 "The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-19T04:23:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071684" ; a owl:Class ; rdfs:label "organism emergence from protective structure" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0071692 obo:IAO_0000115 "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-25T04:00:13Z" ; oboInOwl:hasExactSynonym "protein localisation in extracellular region", "protein localization in extracellular region" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071692" ; a owl:Class ; rdfs:label "protein localization to extracellular region" ; rdfs:subClassOf obo:GO_0008104, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005576 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005576 ] ) ] . obo:GO_0071695 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-02T11:43:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071695" ; a owl:Class ; rdfs:label "anatomical structure maturation" ; rdfs:subClassOf obo:GO_0021700, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048856 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CARO_0000003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CARO_0000003 ] ) ] . obo:GO_0071696 obo:IAO_0000115 "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-02T11:48:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071696" ; a owl:Class ; rdfs:label "ectodermal placode development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005085 ] ) ] . obo:GO_0071697 obo:IAO_0000115 "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-02T11:49:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071697" ; a owl:Class ; rdfs:label "ectodermal placode morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071696 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005085 ] ) ] . obo:GO_0071702 obo:IAO_0000115 "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-08T02:15:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071702" ; a owl:Class ; rdfs:label "organic substance transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_50860 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_50860 ] ) ] . obo:GO_0071704 obo:IAO_0000115 "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-08T03:32:18Z" ; oboInOwl:hasExactSynonym "organic molecular entity metabolic process", "organic molecular entity metabolism", "organic substance metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071704" ; a owl:Class ; rdfs:label "organic substance metabolic process" ; rdfs:subClassOf obo:GO_0008152, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_50860 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_50860 ] ) ] . obo:GO_0071705 obo:IAO_0000115 "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-08T03:56:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071705" ; a owl:Class ; rdfs:label "nitrogen compound transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_51143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_51143 ] ) ] . obo:GO_0071709 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-10T11:19:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071709" ; a owl:Class ; rdfs:label "membrane assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044091 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0071711 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-10T11:57:10Z" ; oboInOwl:hasExactSynonym "basement membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071711" ; a owl:Class ; rdfs:comment "Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer." ; rdfs:label "basement membrane organization" ; rdfs:subClassOf obo:GO_0030198, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005604 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005604 ] ) ] . obo:GO_0071763 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-29T03:59:35Z" ; oboInOwl:hasExactSynonym "nuclear membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear membrane organization and biogenesis" ; oboInOwl:id "GO:0071763" ; a owl:Class ; rdfs:label "nuclear membrane organization" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006998 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031965 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0031965 ] ) ] . obo:GO_0071764 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-29T04:03:37Z" ; oboInOwl:hasExactSynonym "nuclear outer membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear outer membrane organization and biogenesis" ; oboInOwl:id "GO:0071764" ; a owl:Class ; rdfs:label "nuclear outer membrane organization" ; rdfs:subClassOf obo:GO_0071763, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005640 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005640 ] ) ] . obo:GO_0071806 obo:IAO_0000115 "The process in which a protein is transported across a membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-03T02:54:26Z" ; oboInOwl:hasExactSynonym "protein membrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071806" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "protein transmembrane transport" ; rdfs:subClassOf obo:GO_0015031, obo:GO_0055085 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36080 ] ) ] . obo:GO_0071824 obo:IAO_0000115 "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-08T10:03:26Z" ; oboInOwl:hasExactSynonym "DNA-protein complex subunit organization", "protein-DNA complex subunit organisation", "protein-DNA complex subunit organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071824" ; a owl:Class ; rdfs:label "protein-DNA complex organization" ; rdfs:subClassOf obo:GO_0043933, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0032993 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0032993 ] ) ] . obo:GO_0071826 obo:IAO_0000115 "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25143"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-08T10:10:35Z" ; oboInOwl:hasExactSynonym "RNA-protein complex subunit organization", "protein-RNA complex subunit organization", "ribonucleoprotein complex subunit organisation", "ribonucleoprotein complex subunit organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071826" ; a owl:Class ; rdfs:label "protein-RNA complex organization" ; rdfs:subClassOf obo:GO_0043933, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_1990904 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_1990904 ] ) ] . obo:GO_0071840 obo:IAO_0000115 "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-10T01:39:16Z" ; oboInOwl:hasAlternativeId "GO:0071841" ; oboInOwl:hasExactSynonym "cellular component organisation or biogenesis", "cellular component organisation or biogenesis at cellular level", "cellular component organization or biogenesis at cellular level" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071840" ; oboInOwl:inSubset go:goslim_flybase_ribbon, go:goslim_metagenomics ; a owl:Class ; rdfs:label "cellular component organization or biogenesis" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0071867 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-13T02:36:37Z" ; oboInOwl:hasExactSynonym "response to monoamine stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071867" ; a owl:Class ; rdfs:label "response to monoamine" ; rdfs:subClassOf obo:GO_0010243, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_63534 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_63534 ] ) ] . obo:GO_0071868 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-13T02:38:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071868" ; a owl:Class ; rdfs:label "cellular response to monoamine stimulus" ; rdfs:subClassOf obo:GO_0071417, obo:GO_0071867 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_63534 ] ) ] . obo:GO_0071869 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-13T02:51:13Z" ; oboInOwl:hasExactSynonym "response to catecholamine stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071869" ; a owl:Class ; rdfs:label "response to catecholamine" ; rdfs:subClassOf obo:GO_0014070, obo:GO_0071867, obo:GO_1901700, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33567 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33567 ] ) ] . obo:GO_0071870 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-13T02:54:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071870" ; a owl:Class ; rdfs:label "cellular response to catecholamine stimulus" ; rdfs:subClassOf obo:GO_0071407, obo:GO_0071868, obo:GO_0071869, obo:GO_1901701 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33567 ] ) ] . obo:GO_0071873 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-13T03:31:53Z" ; oboInOwl:hasExactSynonym "response to noradrenaline stimulus", "response to norepinephrine stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071873" ; a owl:Class ; rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors." ; rdfs:label "response to norepinephrine" ; rdfs:subClassOf obo:GO_0010033, obo:GO_1901698, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_72587 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050896 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0071874 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-13T03:33:32Z" ; oboInOwl:hasExactSynonym "cellular response to noradrenaline stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071874" ; a owl:Class ; rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors." ; rdfs:label "cellular response to norepinephrine stimulus" ; rdfs:subClassOf obo:GO_0071873, obo:GO_1901699 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0070887 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_72587 ] ) ] . obo:GO_0071887 obo:IAO_0000115 "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-14T12:44:09Z" ; oboInOwl:hasNarrowSynonym "leukocyte apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071887" ; a owl:Class ; rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542)." ; rdfs:label "leukocyte apoptotic process" ; rdfs:subClassOf obo:GO_0006915, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000738 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_7742 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_7742 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000738 ] ) ] . obo:GO_0071890 obo:IAO_0000115 "Binding to bicarbonate ions (CHO3-)." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-14T01:47:43Z" ; oboInOwl:hasExactSynonym "CHO3- ion binding binding", "hydrogencarbonate binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0071890" ; a owl:Class ; rdfs:label "bicarbonate binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_17544 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_17544 ] ) ] . obo:GO_0071897 obo:IAO_0000115 "The biosynthetic process resulting in the formation of DNA." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-15T02:14:33Z" ; oboInOwl:hasExactSynonym "DNA anabolism", "DNA biosynthesis", "DNA formation", "DNA synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071897" ; a owl:Class ; rdfs:label "DNA biosynthetic process" ; rdfs:subClassOf obo:GO_0006259, obo:GO_0009059, obo:GO_0034654, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_16991 ] ) ] . obo:GO_0071930 obo:IAO_0000115 "Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-29T11:12:11Z" ; oboInOwl:hasExactSynonym "negative regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle" ; oboInOwl:id "GO:0071930" ; a owl:Class ; rdfs:label "negative regulation of transcription involved in G1/S transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0000083, obo:GO_0045892 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045892 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000082 ] ) ] . obo:GO_0071931 obo:IAO_0000115 "Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-29T11:15:34Z" ; oboInOwl:hasExactSynonym "positive regulation of transcription from RNA polymerase II promoter involved in G1/S transition of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of transcription from RNA polymerase II promoter during G1/S phase of mitotic cell cycle" ; oboInOwl:id "GO:0071931" ; a owl:Class ; rdfs:label "positive regulation of transcription involved in G1/S transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0000083, obo:GO_0045893 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045893 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000082 ] ) ] . obo:GO_0071944 obo:IAO_0000115 "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-04T01:51:47Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0071944" ; oboInOwl:inSubset go:goslim_flybase_ribbon ; a owl:Class ; rdfs:label "cell periphery" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0071953 obo:IAO_0000115 "An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-11T11:44:57Z" ; oboInOwl:hasExactSynonym "elastic fibre", "elastin fiber" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0071953" ; a owl:Class ; rdfs:label "elastic fiber" ; rdfs:subClassOf obo:GO_0099512, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031012 ] . obo:GO_0071971 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-18T03:44:18Z" ; oboInOwl:hasExactSynonym "extracellular vesicular exosome assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071971" ; a owl:Class ; rdfs:label "extracellular exosome assembly" ; rdfs:subClassOf obo:GO_0016050, obo:GO_0070925, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0097734 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0070062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0070062 ] ) ] . obo:GO_0071981 obo:IAO_0000115 "The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-21T04:45:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071981" ; a owl:Class ; rdfs:label "exit from diapause" ; rdfs:subClassOf obo:GO_0022611 . obo:GO_0072001 obo:IAO_0000115 "The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T10:31:00Z" ; oboInOwl:hasBroadSynonym "urinary system development", "urinary tract development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072001" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "renal system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048731 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001008 ] ) ] . obo:GO_0072003 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T11:18:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "kidney anlage formation" ; oboInOwl:id "GO:0072003" ; a owl:Class ; rdfs:label "kidney rudiment formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060993 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005095 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005095 ] ) ] . obo:GO_0072006 obo:IAO_0000115 "The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T01:37:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nephrogenesis" ; oboInOwl:id "GO:0072006" ; a owl:Class ; rdfs:label "nephron development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001285 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001285 ] ) ] . obo:GO_0072009 obo:IAO_0000115 "The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T02:01:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072009" ; a owl:Class ; rdfs:label "nephron epithelium development" ; rdfs:subClassOf obo:GO_0072073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072006 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004211 ] ) ] . obo:GO_0072028 obo:IAO_0000115 "The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T02:45:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072028" ; a owl:Class ; rdfs:label "nephron morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060993 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072006 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001285 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001285 ] ) ] . obo:GO_0072033 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T02:57:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nephron epithelium formation" ; oboInOwl:id "GO:0072033" ; a owl:Class ; rdfs:label "renal vesicle formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072077 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004209 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004209 ] ) ] . obo:GO_0072036 obo:IAO_0000115 "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T03:04:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072036" ; a owl:Class ; rdfs:label "mesenchymal to epithelial transition involved in renal vesicle formation" ; rdfs:subClassOf obo:GO_0035850, obo:GO_0060231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072033 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060231 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072033 ] ) ] . obo:GO_0072038 obo:IAO_0000115 "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T03:08:05Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072038" ; a owl:Class ; rdfs:label "mesenchymal stem cell maintenance involved in nephron morphogenesis" ; rdfs:subClassOf obo:GO_0035019, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072028 ] . obo:GO_0072039 obo:IAO_0000115 "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T03:08:34Z" ; oboInOwl:hasExactSynonym "regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" ; oboInOwl:hasNarrowSynonym "regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072039" ; a owl:Class ; rdfs:label "regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis" ; rdfs:subClassOf obo:GO_1902337, obo:GO_1904672, obo:GO_2001053, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072038 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1901145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1901145 ] ) ] . obo:GO_0072040 obo:IAO_0000115 "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T03:09:30Z" ; oboInOwl:hasExactSynonym "negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" ; oboInOwl:hasNarrowSynonym "negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072040" ; a owl:Class ; rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072039, obo:GO_1902338, obo:GO_1904673, obo:GO_2001054, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0072038 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1901145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1901145 ] ) ] . obo:GO_0072041 obo:IAO_0000115 "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T03:10:32Z" ; oboInOwl:hasExactSynonym "positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis" ; oboInOwl:hasNarrowSynonym "positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072041" ; a owl:Class ; rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072039, obo:GO_1902339, obo:GO_1904674, obo:GO_2001055, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0072038 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1901145 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1901145 ] ) ] . obo:GO_0072044 obo:IAO_0000115 "The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T03:18:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072044" ; a owl:Class ; rdfs:label "collecting duct development" ; rdfs:subClassOf obo:GO_0035295, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001232 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001232 ] ) ] . obo:GO_0072048 obo:IAO_0000115 "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T03:31:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "renal system pattern formation" ; oboInOwl:id "GO:0072048" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "renal system pattern specification" ; rdfs:subClassOf obo:GO_0007389, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072001 ] . obo:GO_0072055 obo:IAO_0000115 "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T04:01:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072055" ; a owl:Class ; rdfs:label "renal cortex development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001225 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001225 ] ) ] . obo:GO_0072059 obo:IAO_0000115 "The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T04:07:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072059" ; a owl:Class ; rdfs:label "cortical collecting duct development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004203 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004203 ] ) ] . obo:GO_0072071 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T04:34:31Z" ; oboInOwl:hasExactSynonym "kidney interstitial cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072071" ; a owl:Class ; rdfs:label "kidney interstitial fibroblast differentiation" ; rdfs:subClassOf obo:GO_0061005, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000692 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000692 ] ) ] . obo:GO_0072073 obo:IAO_0000115 "The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T04:37:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072073" ; a owl:Class ; rdfs:label "kidney epithelium development" ; rdfs:subClassOf obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004819 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004819 ] ) ] . obo:GO_0072074 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T04:39:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072074" ; a owl:Class ; rdfs:label "kidney mesenchyme development" ; rdfs:subClassOf obo:GO_0060485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003918 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003918 ] ) ] . obo:GO_0072075 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T04:40:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072075" ; a owl:Class ; rdfs:label "metanephric mesenchyme development" ; rdfs:subClassOf obo:GO_0072074, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003220 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003220 ] ) ] . obo:GO_0072076 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-01-25T04:40:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072076" ; a owl:Class ; rdfs:label "nephrogenic mesenchyme development" ; rdfs:subClassOf obo:GO_0072074, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072006 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004208 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004208 ] ) ] . obo:GO_0072077 obo:IAO_0000115 "The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-01T02:21:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072077" ; a owl:Class ; rdfs:label "renal vesicle morphogenesis" ; rdfs:subClassOf obo:GO_0002009, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072087 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072088 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004209 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004209 ] ) ] . obo:GO_0072078 obo:IAO_0000115 "The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-01T02:25:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072078" ; a owl:Class ; rdfs:label "nephron tubule morphogenesis" ; rdfs:subClassOf obo:GO_0061333, obo:GO_0072088, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072080 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0001231 ] ) ] . obo:GO_0072079 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-01T02:29:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072079" ; a owl:Class ; rdfs:label "nephron tubule formation" ; rdfs:subClassOf obo:GO_0001838, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072078 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0001231 ] ) ] . obo:GO_0072080 obo:IAO_0000115 "The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-01T02:32:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072080" ; a owl:Class ; rdfs:label "nephron tubule development" ; rdfs:subClassOf obo:GO_0061326, obo:GO_0072009, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001231 ] ) ] . obo:GO_0072087 obo:IAO_0000115 "The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-08T01:18:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072087" ; a owl:Class ; rdfs:label "renal vesicle development" ; rdfs:subClassOf obo:GO_0072073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072009 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004209 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004209 ] ) ] . obo:GO_0072088 obo:IAO_0000115 "The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-08T01:19:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072088" ; a owl:Class ; rdfs:label "nephron epithelium morphogenesis" ; rdfs:subClassOf obo:GO_0002009, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072009 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072028 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004211 ] ) ] . obo:GO_0072089 obo:IAO_0000115 "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-08T02:03:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072089" ; a owl:Class ; rdfs:label "stem cell proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0017145 ], [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000034 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000034 ] ) ] . obo:GO_0072091 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-08T02:09:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072091" ; a owl:Class ; rdfs:label "regulation of stem cell proliferation" ; rdfs:subClassOf obo:GO_0042127, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072089 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072089 ] ) ] . obo:GO_0072093 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-10T01:17:11Z" ; oboInOwl:hasExactSynonym "metanephros formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072093" ; a owl:Class ; rdfs:label "metanephric renal vesicle formation" ; rdfs:subClassOf obo:GO_0072033, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072283 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005147 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005147 ] ) ] . obo:GO_0072098 obo:IAO_0000115 "The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-10T02:06:24Z" ; oboInOwl:hasExactSynonym "kidney anterior/posterior pattern specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "anterior/posterior pattern formation involved in kidney development", "kidney anterior/posterior pattern formation" ; oboInOwl:id "GO:0072098" ; a owl:Class ; rdfs:label "anterior/posterior pattern specification involved in kidney development" ; rdfs:subClassOf obo:GO_0009952, obo:GO_0061004 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009952 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0072099 obo:IAO_0000115 "The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-10T02:12:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ureteric bud anterior/posterior pattern formation" ; oboInOwl:id "GO:0072099" ; a owl:Class ; rdfs:label "anterior/posterior pattern specification involved in ureteric bud development" ; rdfs:subClassOf obo:GO_0061227, obo:GO_0072098, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001657 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009952 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001657 ] ) ] . obo:GO_0072105 obo:IAO_0000115 "A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-10T03:07:54Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072105" ; a owl:Class ; rdfs:label "ureteric peristalsis" ; rdfs:subClassOf obo:GO_0014849, obo:GO_0030432, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030432 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:UBERON_0000056 ] ) ] . obo:GO_0072106 obo:IAO_0000115 "Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-12T02:34:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072106" ; a owl:Class ; rdfs:label "regulation of ureteric bud formation" ; rdfs:subClassOf obo:GO_0061217, obo:GO_1905276, obo:GO_2000027, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060676 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060676 ] ) ] . obo:GO_0072107 obo:IAO_0000115 "Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-12T02:37:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072107" ; a owl:Class ; rdfs:label "positive regulation of ureteric bud formation" ; rdfs:subClassOf obo:GO_0072106, obo:GO_0110110, obo:GO_1905278, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060676 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060676 ] ) ] . obo:GO_0072108 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-12T02:45:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072108" ; a owl:Class ; rdfs:label "positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis" ; rdfs:subClassOf obo:GO_0003339, obo:GO_1905332, obo:GO_2000698, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003337 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003337 ] ) ] . obo:GO_0072111 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T10:48:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072111" ; a owl:Class ; rdfs:label "cell proliferation involved in kidney development" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0072114 obo:IAO_0000115 "The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T11:12:15Z" ; oboInOwl:hasExactSynonym "pronephric kidney morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072114" ; a owl:Class ; rdfs:label "pronephros morphogenesis" ; rdfs:subClassOf obo:GO_0060993, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002120 ] ) ] . obo:GO_0072116 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T11:16:26Z" ; oboInOwl:hasExactSynonym "pronephric kidney formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072116" ; a owl:Class ; rdfs:label "pronephros formation" ; rdfs:subClassOf obo:GO_0048645, obo:GO_0072003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072114 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002120 ] ) ] . obo:GO_0072120 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T11:25:48Z" ; oboInOwl:hasExactSynonym "pronephric kidney maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072120" ; a owl:Class ; rdfs:label "pronephros maturation" ; rdfs:subClassOf obo:GO_0048799, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048793 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0002120 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:UBERON_0002120 ] ) ] . obo:GO_0072127 obo:IAO_0000115 "The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T02:02:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072127" ; a owl:Class ; rdfs:label "renal capsule development" ; rdfs:subClassOf obo:GO_0061448, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0002015 ] ) ] . obo:GO_0072128 obo:IAO_0000115 "The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T02:06:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072128" ; a owl:Class ; rdfs:label "renal capsule morphogenesis" ; rdfs:subClassOf obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072127 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002015 ] ) ] . obo:GO_0072129 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T02:08:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072129" ; a owl:Class ; rdfs:label "renal capsule formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072128 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0002015 ] ) ] . obo:GO_0072131 obo:IAO_0000115 "The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T02:16:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072131" ; a owl:Class ; rdfs:label "kidney mesenchyme morphogenesis" ; rdfs:subClassOf obo:GO_0072132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072074 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003918 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003918 ] ) ] . obo:GO_0072132 obo:IAO_0000115 "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T02:17:15Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072132" ; a owl:Class ; rdfs:label "mesenchyme morphogenesis" ; rdfs:subClassOf obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009887 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060485 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003104 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003104 ] ) ] . obo:GO_0072133 obo:IAO_0000115 "The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T02:20:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072133" ; a owl:Class ; rdfs:label "metanephric mesenchyme morphogenesis" ; rdfs:subClassOf obo:GO_0072131, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072075 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003220 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003220 ] ) ] . obo:GO_0072134 obo:IAO_0000115 "The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T02:21:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072134" ; a owl:Class ; rdfs:label "nephrogenic mesenchyme morphogenesis" ; rdfs:subClassOf obo:GO_0072131, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072076 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004208 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0004208 ] ) ] . obo:GO_0072138 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-22T02:40:38Z" ; oboInOwl:hasBroadSynonym "ureteric bud mesenchymal cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072138" ; a owl:Class ; rdfs:label "mesenchymal cell proliferation involved in ureteric bud development" ; rdfs:subClassOf obo:GO_0010463, obo:GO_0061209, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001657 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0010463 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001657 ] ) ] . obo:GO_0072141 obo:IAO_0000115 "The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-24T01:39:05Z" ; oboInOwl:hasExactSynonym "kidney interstitial cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072141" ; a owl:Class ; rdfs:label "renal interstitial fibroblast development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072071 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_1000692 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_1000692 ] ) ] . obo:GO_0072155 obo:IAO_0000115 "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-24T02:21:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072155" ; a owl:Class ; rdfs:label "epithelial cell migration involved in nephron tubule morphogenesis" ; rdfs:subClassOf obo:GO_0010631, obo:GO_0035787, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072078 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0010631 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072078 ] ) ] . obo:GO_0072160 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-24T02:40:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072160" ; a owl:Class ; rdfs:label "nephron tubule epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0035850, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072080 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000494 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000494 ] ) ] . obo:GO_0072161 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T01:31:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072161" ; a owl:Class ; rdfs:label "mesenchymal cell differentiation involved in kidney development" ; rdfs:subClassOf obo:GO_0061005, obo:GO_2001012, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072074 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048762 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0072163 obo:IAO_0000115 "The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T01:40:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072163" ; a owl:Class ; rdfs:label "mesonephric epithelium development" ; rdfs:subClassOf obo:GO_0072073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001823 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005103 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005103 ] ) ] . obo:GO_0072164 obo:IAO_0000115 "The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T01:45:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072164" ; a owl:Class ; rdfs:label "mesonephric tubule development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0072163, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000083 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000083 ] ) ] . obo:GO_0072170 obo:IAO_0000115 "The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T01:58:18Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072170" ; a owl:Class ; rdfs:label "metanephric tubule development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0072207, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005106 ] ) ] . obo:GO_0072171 obo:IAO_0000115 "The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:02:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072171" ; a owl:Class ; rdfs:label "mesonephric tubule morphogenesis" ; rdfs:subClassOf obo:GO_0072078, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072164 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000083 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000083 ] ) ] . obo:GO_0072172 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:02:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072172" ; a owl:Class ; rdfs:label "mesonephric tubule formation" ; rdfs:subClassOf obo:GO_0072079, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072171 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000083 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0000083 ] ) ] . obo:GO_0072173 obo:IAO_0000115 "The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:06:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072173" ; a owl:Class ; rdfs:label "metanephric tubule morphogenesis" ; rdfs:subClassOf obo:GO_0060562, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072170 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005106 ] ) ] . obo:GO_0072174 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a metanephric tubule." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:07:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072174" ; a owl:Class ; rdfs:label "metanephric tubule formation" ; rdfs:subClassOf obo:GO_0072175, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005106 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005106 ] ) ] . obo:GO_0072175 obo:IAO_0000115 "The developmental process pertaining to the initial formation of an epithelial tube." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22302"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:15:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072175" ; a owl:Class ; rdfs:label "epithelial tube formation" ; rdfs:subClassOf obo:GO_0035148, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060562 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0035148 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003914 ] ) ] . obo:GO_0072176 obo:IAO_0000115 "The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:27:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072176" ; a owl:Class ; rdfs:label "nephric duct development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0072073, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0009201 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0009201 ] ) ] . obo:GO_0072177 obo:IAO_0000115 "The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:32:22Z" ; oboInOwl:hasExactSynonym "Wolffian duct development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072177" ; a owl:Class ; rdfs:label "mesonephric duct development" ; rdfs:subClassOf obo:GO_0072164, obo:GO_0072176, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003074 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0003074 ] ) ] . obo:GO_0072178 obo:IAO_0000115 "The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:35:29Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072178" ; a owl:Class ; rdfs:label "nephric duct morphogenesis" ; rdfs:subClassOf obo:GO_0060562, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072176 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0009201 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0009201 ] ) ] . obo:GO_0072179 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:35:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072179" ; a owl:Class ; rdfs:label "nephric duct formation" ; rdfs:subClassOf obo:GO_0072175, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072178 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0009201 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0009201 ] ) ] . obo:GO_0072180 obo:IAO_0000115 "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:37:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "Wolffian duct morphogenesis" ; oboInOwl:id "GO:0072180" ; a owl:Class ; rdfs:label "mesonephric duct morphogenesis" ; rdfs:subClassOf obo:GO_0072171, obo:GO_0072178, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072177 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003074 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0003074 ] ) ] . obo:GO_0072181 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:38:03Z" ; oboInOwl:hasExactSynonym "Wolffian duct formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072181" ; a owl:Class ; rdfs:label "mesonephric duct formation" ; rdfs:subClassOf obo:GO_0072172, obo:GO_0072179, obo:GO_0072180, [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003074 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0003074 ] ) ] . obo:GO_0072182 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:45:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072182" ; a owl:Class ; rdfs:label "regulation of nephron tubule epithelial cell differentiation" ; rdfs:subClassOf obo:GO_2000696, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072160 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072160 ] ) ] . obo:GO_0072183 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-26T02:47:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072183" ; a owl:Class ; rdfs:label "negative regulation of nephron tubule epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0072182, obo:GO_0090185, obo:GO_2000697, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0072160 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0072160 ] ) ] . obo:GO_0072189 obo:IAO_0000115 "The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-01T01:44:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072189" ; a owl:Class ; rdfs:label "ureter development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0000056 ] ) ] . obo:GO_0072191 obo:IAO_0000115 "The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-01T01:48:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072191" ; a owl:Class ; rdfs:label "ureter smooth muscle development" ; rdfs:subClassOf obo:GO_0048745, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072189 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0009919 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0009919 ] ) ] . obo:GO_0072193 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-01T01:55:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072193" ; a owl:Class ; rdfs:label "ureter smooth muscle cell differentiation" ; rdfs:subClassOf obo:GO_0051145, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072191 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000979 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000979 ] ) ] . obo:GO_0072194 obo:IAO_0000115 "The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-01T02:05:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072194" ; a owl:Class ; rdfs:label "kidney smooth muscle tissue development" ; rdfs:subClassOf obo:GO_0048745, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001822 ] . obo:GO_0072197 obo:IAO_0000115 "The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-01T02:24:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072197" ; a owl:Class ; rdfs:label "ureter morphogenesis" ; rdfs:subClassOf obo:GO_0009887, obo:GO_0035239, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072189 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000056 ] ) ] . obo:GO_0072198 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-01T03:24:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ureter mesenchymal cell proliferation", "ureteral mesenchymal cell proliferation" ; oboInOwl:id "GO:0072198" ; a owl:Class ; rdfs:label "mesenchymal cell proliferation involved in ureter development" ; rdfs:subClassOf obo:GO_0010463, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072189 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0010463 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072189 ] ) ] . obo:GO_0072199 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-01T03:38:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of ureter mesenchymal cell proliferation", "regulation of ureteral mesenchymal cell proliferation" ; oboInOwl:id "GO:0072199" ; a owl:Class ; rdfs:label "regulation of mesenchymal cell proliferation involved in ureter development" ; rdfs:subClassOf obo:GO_0010464, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072198 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072198 ] ) ] . obo:GO_0072200 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-01T03:42:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of ureter mesenchymal cell proliferation", "negative regulation of ureteral mesenchymal cell proliferation" ; oboInOwl:id "GO:0072200" ; a owl:Class ; rdfs:label "negative regulation of mesenchymal cell proliferation involved in ureter development" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0051241, obo:GO_0072199, obo:GO_0072201, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0072198 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0072198 ] ) ] . obo:GO_0072201 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-01T03:43:29Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072201" ; a owl:Class ; rdfs:label "negative regulation of mesenchymal cell proliferation" ; rdfs:subClassOf obo:GO_0008285, obo:GO_0010464, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010463 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010463 ] ) ] . obo:GO_0072202 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T10:40:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072202" ; a owl:Class ; rdfs:label "cell differentiation involved in metanephros development" ; rdfs:subClassOf obo:GO_0061005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ) ] . obo:GO_0072203 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T10:42:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072203" ; a owl:Class ; rdfs:label "cell proliferation involved in metanephros development" ; rdfs:subClassOf obo:GO_0072111, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ) ] . obo:GO_0072204 obo:IAO_0000115 "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T10:54:36Z" ; oboInOwl:hasExactSynonym "cell-cell signalling involved in metanephros development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072204" ; a owl:Class ; rdfs:label "cell-cell signaling involved in metanephros development" ; rdfs:subClassOf obo:GO_0060995, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ) ] . obo:GO_0072205 obo:IAO_0000115 "The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T11:15:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072205" ; a owl:Class ; rdfs:label "metanephric collecting duct development" ; rdfs:subClassOf obo:GO_0072044, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0004737 ] ) ] . obo:GO_0072207 obo:IAO_0000115 "The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T11:50:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072207" ; a owl:Class ; rdfs:label "metanephric epithelium development" ; rdfs:subClassOf obo:GO_0072073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005108 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005108 ] ) ] . obo:GO_0072208 obo:IAO_0000115 "The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T11:51:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072208" ; a owl:Class ; rdfs:label "metanephric smooth muscle tissue development" ; rdfs:subClassOf obo:GO_0072194, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005109 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005109 ] ) ] . obo:GO_0072210 obo:IAO_0000115 "The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T12:52:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072210" ; a owl:Class ; rdfs:label "metanephric nephron development" ; rdfs:subClassOf obo:GO_0072006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005110 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005110 ] ) ] . obo:GO_0072213 obo:IAO_0000115 "The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T01:25:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072213" ; a owl:Class ; rdfs:label "metanephric capsule development" ; rdfs:subClassOf obo:GO_0072127, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005137 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005137 ] ) ] . obo:GO_0072214 obo:IAO_0000115 "The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T01:29:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072214" ; a owl:Class ; rdfs:label "metanephric cortex development" ; rdfs:subClassOf obo:GO_0060485, obo:GO_0072055, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005113 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005113 ] ) ] . obo:GO_0072215 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072215" ; a owl:Class ; rdfs:label "regulation of metanephros development" ; rdfs:subClassOf obo:GO_0090183, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001656 ] ) ] . obo:GO_0072216 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T01:40:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072216" ; a owl:Class ; rdfs:label "positive regulation of metanephros development" ; rdfs:subClassOf obo:GO_0072215, obo:GO_0090184, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001656 ] ) ] . obo:GO_0072217 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T01:45:48Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072217" ; a owl:Class ; rdfs:label "negative regulation of metanephros development" ; rdfs:subClassOf obo:GO_0072215, obo:GO_0090185, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001656 ] ) ] . obo:GO_0072219 obo:IAO_0000115 "The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T03:34:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072219" ; a owl:Class ; rdfs:label "metanephric cortical collecting duct development" ; rdfs:subClassOf obo:GO_0072059, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005115 ] ) ] . obo:GO_0072234 obo:IAO_0000115 "The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-18T03:41:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072234" ; a owl:Class ; rdfs:label "metanephric nephron tubule development" ; rdfs:subClassOf obo:GO_0072080, obo:GO_0072170, obo:GO_0072243, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005146 ] ) ] . obo:GO_0072243 obo:IAO_0000115 "The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-19T03:29:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072243" ; a owl:Class ; rdfs:label "metanephric nephron epithelium development" ; rdfs:subClassOf obo:GO_0072009, obo:GO_0072207, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005134 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0005134 ] ) ] . obo:GO_0072257 obo:IAO_0000115 "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-19T04:11:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072257" ; a owl:Class ; rdfs:label "metanephric nephron tubule epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0072160, obo:GO_0072202, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072234 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000123 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_1000123 ] ) ] . obo:GO_0072265 obo:IAO_0000115 "The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-30T02:54:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072265" ; a owl:Class ; rdfs:label "metanephric capsule morphogenesis" ; rdfs:subClassOf obo:GO_0072128, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072213 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005137 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005137 ] ) ] . obo:GO_0072266 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-30T02:56:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072266" ; a owl:Class ; rdfs:label "metanephric capsule formation" ; rdfs:subClassOf obo:GO_0072129, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072265 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005137 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005137 ] ) ] . obo:GO_0072268 obo:IAO_0000115 "Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-30T03:06:30Z" ; oboInOwl:hasExactSynonym "metanephros pattern specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "metanephros pattern formation", "pattern formation involved in metanephros development" ; oboInOwl:id "GO:0072268" ; a owl:Class ; rdfs:label "pattern specification involved in metanephros development" ; rdfs:subClassOf obo:GO_0061004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007389 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001656 ] ) ] . obo:GO_0072273 obo:IAO_0000115 "The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-30T03:33:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072273" ; a owl:Class ; rdfs:label "metanephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003338 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072210 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005110 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005110 ] ) ] . obo:GO_0072282 obo:IAO_0000115 "The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-01T03:25:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072282" ; a owl:Class ; rdfs:label "metanephric nephron tubule morphogenesis" ; rdfs:subClassOf obo:GO_0072078, obo:GO_0072173, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072234 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072273 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005146 ] ) ] . obo:GO_0072283 obo:IAO_0000115 "The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-01T03:28:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072283" ; a owl:Class ; rdfs:label "metanephric renal vesicle morphogenesis" ; rdfs:subClassOf obo:GO_0072077, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072273 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005147 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0005147 ] ) ] . obo:GO_0072285 obo:IAO_0000115 "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-01T03:43:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072285" ; a owl:Class ; rdfs:label "mesenchymal to epithelial transition involved in metanephric renal vesicle formation" ; rdfs:subClassOf obo:GO_0003337, obo:GO_0072036, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072093 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0060231 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072093 ] ) ] . obo:GO_0072289 obo:IAO_0000115 "The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-09T03:47:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072289" ; a owl:Class ; rdfs:label "metanephric nephron tubule formation" ; rdfs:subClassOf obo:GO_0072079, obo:GO_0072174, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072282 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0005146 ] ) ] . obo:GO_0072290 obo:IAO_0000115 "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-09T03:52:29Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072290" ; a owl:Class ; rdfs:label "epithelial cell migration involved in metanephric nephron tubule morphogenesis" ; rdfs:subClassOf obo:GO_0035788, obo:GO_0072155, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072282 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0010631 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072282 ] ) ] . obo:GO_0072304 obo:IAO_0000115 "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-09T05:03:41Z" ; oboInOwl:hasExactSynonym "regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" ; oboInOwl:hasNarrowSynonym "regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072304" ; a owl:Class ; rdfs:label "regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072039, obo:GO_1900211, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072309 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1901147 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1901147 ] ) ] . obo:GO_0072305 obo:IAO_0000115 "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-09T05:03:41Z" ; oboInOwl:hasExactSynonym "negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" ; oboInOwl:hasNarrowSynonym "negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072305" ; a owl:Class ; rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072040, obo:GO_0072304, obo:GO_1900212, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0072309 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1901147 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1901147 ] ) ] . obo:GO_0072306 obo:IAO_0000115 "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-09T05:03:41Z" ; oboInOwl:hasExactSynonym "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis" ; oboInOwl:hasNarrowSynonym "positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072306" ; a owl:Class ; rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072041, obo:GO_0072304, obo:GO_1900213, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0072309 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1901147 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1901147 ] ) ] . obo:GO_0072307 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-09T05:03:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072307" ; a owl:Class ; rdfs:label "regulation of metanephric nephron tubule epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0072182, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072257 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072257 ] ) ] . obo:GO_0072308 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-09T05:03:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072308" ; a owl:Class ; rdfs:label "negative regulation of metanephric nephron tubule epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0072183, obo:GO_0072307, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0072257 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0072257 ] ) ] . obo:GO_0072309 obo:IAO_0000115 "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-04-09T05:03:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072309" ; a owl:Class ; rdfs:label "mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis" ; rdfs:subClassOf obo:GO_0072038, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072273 ] . obo:GO_0072329 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-02T04:41:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072329" ; a owl:Class ; rdfs:label "monocarboxylic acid catabolic process" ; rdfs:subClassOf obo:GO_0032787, obo:GO_0046395, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35757 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_35757 ] ) ] . obo:GO_0072330 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-02T04:51:32Z" ; oboInOwl:hasExactSynonym "monocarboxylic acid anabolism", "monocarboxylic acid biosynthesis", "monocarboxylic acid formation", "monocarboxylic acid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072330" ; a owl:Class ; rdfs:label "monocarboxylic acid biosynthetic process" ; rdfs:subClassOf obo:GO_0032787, obo:GO_0046394, [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_35757 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009058 [ a owl:Restriction ; owl:onProperty obo:RO_0004008 ; owl:someValuesFrom obo:CHEBI_35757 ] ) ] . obo:GO_0072347 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-10T01:26:18Z" ; oboInOwl:hasExactSynonym "response to anaesthetic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072347" ; a owl:Class ; rdfs:label "response to anesthetic" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0072348 obo:IAO_0000115 "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-11T11:43:56Z" ; oboInOwl:hasExactSynonym "sulfur-containing compound transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072348" ; a owl:Class ; rdfs:label "sulfur compound transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_26835 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_26835 ] ) ] . obo:GO_0072359 obo:IAO_0000115 "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-16T11:27:39Z" ; oboInOwl:hasAlternativeId "GO:0072358" ; oboInOwl:hasNarrowSynonym "cardiovascular system development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072359" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "circulatory system development" ; rdfs:subClassOf obo:GO_0048731, [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001009 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001009 ] ) ] . obo:GO_0072360 obo:IAO_0000115 "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-16T11:46:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072360" ; a owl:Class ; rdfs:label "vascular cord development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072359 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006965 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0006965 ] ) ] . obo:GO_0072384 obo:IAO_0000115 "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-12-01T04:59:11Z" ; oboInOwl:hasExactSynonym "microtubule-based organelle localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072384" ; a owl:Class ; rdfs:label "organelle transport along microtubule" ; rdfs:subClassOf obo:GO_0010970, obo:GO_0051656 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0072488 obo:IAO_0000115 "The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22228"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-12-10T10:29:57Z" ; oboInOwl:hasAlternativeId "GO:0015696" ; oboInOwl:hasBroadSynonym "ammonia transport", "ammonium transport" ; oboInOwl:hasExactSynonym "ammonium membrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072488" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "ammonium transmembrane transport" ; rdfs:subClassOf obo:GO_0071705, obo:GO_0098662, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_28938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_28938 ] ) ] . obo:GO_0072520 obo:IAO_0000115 "The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-01-04T12:50:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072520" ; a owl:Class ; rdfs:label "seminiferous tubule development" ; rdfs:subClassOf obo:GO_0035295, obo:GO_0048608, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008584 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001343 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001343 ] ) ] . obo:GO_0072537 obo:IAO_0000115 "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-01-14T04:35:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072537" ; a owl:Class ; rdfs:label "fibroblast activation" ; rdfs:subClassOf obo:GO_0001775, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001775 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000057 ] ) ] . obo:GO_0072560 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-01-27T01:57:14Z" ; oboInOwl:hasExactSynonym "pancreatic B cell maturation", "pancreatic beta cell maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072560" ; a owl:Class ; rdfs:comment "These processes continue to 60 DPA in Gossypium spp." ; rdfs:label "type B pancreatic cell maturation" ; rdfs:subClassOf obo:GO_0002071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0003323 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000169 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0021700 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000169 ] ) ] . obo:GO_0072575 obo:IAO_0000115 "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-02T03:37:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072575" ; a owl:Class ; rdfs:label "epithelial cell proliferation involved in liver morphogenesis" ; rdfs:subClassOf obo:GO_0050673, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072576 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050673 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072576 ] ) ] . obo:GO_0072576 obo:IAO_0000115 "The process in which the anatomical structures of the liver are generated and organized." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-02T03:41:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072576" ; a owl:Class ; rdfs:label "liver morphogenesis" ; rdfs:subClassOf obo:GO_0022612, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001889 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002107 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0002107 ] ) ] . obo:GO_0072577 obo:IAO_0000115 "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-02T03:56:24Z" ; oboInOwl:hasExactSynonym "apoptosis of endothelial cells", "endothelial cell programmed cell death by apoptosis", "killing of endothelial cells", "programmed cell death of endothelial cells by apoptosis", "programmed cell death, endothelial cells" ; oboInOwl:hasNarrowSynonym "endothelial cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072577" ; a owl:Class ; rdfs:label "endothelial cell apoptotic process" ; rdfs:subClassOf obo:GO_1904019, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000115 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000115 ] ) ] . obo:GO_0072592 obo:IAO_0000115 "The chemical reactions and pathways involving diatomic oxygen (O2)." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-11T10:46:51Z" ; oboInOwl:hasExactSynonym "diatomic oxygen metabolic process", "oxygen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072592" ; a owl:Class ; rdfs:label "oxygen metabolic process" ; rdfs:subClassOf obo:GO_0044237, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_15379 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_15379 ] ) ] . obo:GO_0072594 obo:IAO_0000115 "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T01:56:51Z" ; oboInOwl:hasExactSynonym "establishment of protein localisation to organelle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072594" ; a owl:Class ; rdfs:label "establishment of protein localization to organelle" ; rdfs:subClassOf obo:GO_0033365, obo:GO_0045184 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045184 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0072595 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:09:13Z" ; oboInOwl:hasExactSynonym "maintenance of protein localisation to organelle", "maintenance of protein localization to organelle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072595" ; a owl:Class ; rdfs:label "maintenance of protein localization in organelle" ; rdfs:subClassOf obo:GO_0032507, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033365 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0072656 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:30:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072656" ; a owl:Class ; rdfs:label "maintenance of protein location in mitochondrion" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070585 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0072657 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a specific location in a membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:35:18Z" ; oboInOwl:hasExactSynonym "protein localisation in membrane", "protein localization in membrane" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072657" ; oboInOwl:inSubset go:prokaryote_subset ; a owl:Class ; rdfs:label "protein localization to membrane" ; rdfs:subClassOf obo:GO_0008104, obo:GO_0051668 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0072659 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-07-10T10:29:23Z" ; oboInOwl:hasAlternativeId "GO:0072661", "GO:0090002" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein localisation in plasma membrane", "protein localization in plasma membrane", "protein targeting to plasma membrane", "protein-plasma membrane targeting" ; oboInOwl:id "GO:0072659" ; oboInOwl:inSubset go:goslim_generic, go:goslim_pombe ; a owl:Class ; rdfs:label "protein localization to plasma membrane" ; rdfs:subClassOf obo:GO_0072657, obo:GO_1990778, [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005622 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0072662 obo:IAO_0000115 "A process in which a protein is transported to, or maintained at, a location in a peroxisome." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:50:04Z" ; oboInOwl:hasExactSynonym "protein localisation to peroxisome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072662" ; a owl:Class ; rdfs:label "protein localization to peroxisome" ; rdfs:subClassOf obo:GO_0007031, obo:GO_0033365 . obo:GO_0072664 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:51:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072664" ; a owl:Class ; rdfs:label "maintenance of protein location in peroxisome" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072662 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005777 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005777 ] ) ] . obo:GO_0072665 obo:IAO_0000115 "A process in which a protein is transported to, or maintained at, a location in a vacuole." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:55:35Z" ; oboInOwl:hasExactSynonym "protein localisation to vacuole" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072665" ; a owl:Class ; rdfs:label "protein localization to vacuole" ; rdfs:subClassOf obo:GO_0033365, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0072666 obo:IAO_0000115 "The directed movement of a protein to a specific location in a vacuole." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:56:29Z" ; oboInOwl:hasExactSynonym "establishment of protein localisation to vacuole" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072666" ; a owl:Class ; rdfs:label "establishment of protein localization to vacuole" ; rdfs:subClassOf obo:GO_0072594, obo:GO_0072665 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045184 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0072667 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:56:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072667" ; a owl:Class ; rdfs:label "maintenance of protein location in vacuole" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072665 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0072676 obo:IAO_0000115 "The movement of a lymphocyte within or between different tissues and organs of the body." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-22T03:38:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072676" ; a owl:Class ; rdfs:label "lymphocyte migration" ; rdfs:subClassOf obo:GO_0071674, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000542 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000542 ] ) ] . obo:GO_0072678 obo:IAO_0000115 "The movement of a T cell within or between different tissues and organs of the body." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-22T03:40:40Z" ; oboInOwl:hasExactSynonym "T lymphocyte migration", "T-cell migration", "T-lymphocyte migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072678" ; a owl:Class ; rdfs:label "T cell migration" ; rdfs:subClassOf obo:GO_0072676, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000084 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000084 ] ) ] . obo:GO_0072686 obo:IAO_0000115 "A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-07-08T05:08:16Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0072686" ; a owl:Class ; rdfs:label "mitotic spindle" ; rdfs:subClassOf obo:GO_0005819 . obo:GO_0072687 obo:IAO_0000115 "A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-07-08T05:17:08Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0072687" ; a owl:Class ; rdfs:label "meiotic spindle" ; rdfs:subClassOf obo:GO_0005819 . obo:GO_0072697 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, the cell cortex." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-04-11T01:16:33Z" ; oboInOwl:hasExactSynonym "protein localisation to cell cortex" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072697" ; a owl:Class ; rdfs:label "protein localization to cell cortex" ; rdfs:subClassOf obo:GO_1990778, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005938 ] ) ] . obo:GO_0072698 obo:IAO_0000115 "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-04-11T01:19:35Z" ; oboInOwl:hasExactSynonym "protein localisation to microtubule cytoskeleton" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072698" ; a owl:Class ; rdfs:label "protein localization to microtubule cytoskeleton" ; rdfs:subClassOf obo:GO_0044380, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0015630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0015630 ] ) ] . obo:GO_0072710 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-04-11T04:15:42Z" ; oboInOwl:hasExactSynonym "response to HU" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072710" ; a owl:Class ; rdfs:label "response to hydroxyurea" ; rdfs:subClassOf obo:GO_0010033, obo:GO_1901698 . obo:GO_0080090 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2009-04-22T04:30:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0080090" ; a owl:Class ; rdfs:label "regulation of primary metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044238 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044238 ] ) ] . obo:GO_0080134 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2009-05-06T04:51:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0080134" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "regulation of response to stress" ; rdfs:subClassOf obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006950 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006950 ] ) ] . obo:GO_0080135 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2009-05-06T05:02:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0080135" ; a owl:Class ; rdfs:label "regulation of cellular response to stress" ; rdfs:subClassOf obo:GO_0050794, obo:GO_0080134, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033554 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033554 ] ) ] . obo:GO_0080144 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2010-01-27T04:47:27Z" ; oboInOwl:hasBroadSynonym "amino acid homeostasis" ; oboInOwl:hasExactSynonym "cellular amino acid homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0080144" ; a owl:Class ; rdfs:label "intracellular amino acid homeostasis" ; rdfs:subClassOf obo:GO_0055082, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_33709 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055082 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_33709 ] ) ] . obo:GO_0080154 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2010-09-01T03:44:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0080154" ; a owl:Class ; rdfs:label "regulation of fertilization" ; rdfs:subClassOf obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009566 ] ) ] . obo:GO_0080171 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2011-04-25T04:40:46Z" ; oboInOwl:hasExactSynonym "lytic vacuole organisation" ; oboInOwl:hasNarrowSynonym "lytic vacuolar assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lytic vacuole biogenesis", "lytic vacuole organization and biogenesis" ; oboInOwl:id "GO:0080171" ; a owl:Class ; rdfs:label "lytic vacuole organization" ; rdfs:subClassOf obo:GO_0007033, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0000323 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0000323 ] ) ] . obo:GO_0085029 obo:IAO_0000115 "The aggregation, arrangement and bonding together of the extracellular matrix." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-07-14T12:52:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0085029" ; a owl:Class ; rdfs:label "extracellular matrix assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0030198, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0031012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0031012 ] ) ] . obo:GO_0086001 obo:IAO_0000115 "An action potential that occurs in a cardiac muscle cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-10T07:45:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086001" ; a owl:Class ; rdfs:label "cardiac muscle cell action potential" ; rdfs:subClassOf obo:GO_0001508, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000746 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001508 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000746 ] ) ] . obo:GO_0086015 obo:IAO_0000115 "An action potential that occurs in a sinoatrial node cardiac muscle cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-10T08:50:15Z" ; oboInOwl:hasExactSynonym "SA node cardiac muscle cell action potential", "SAN cardiac muscle cell action potential", "sinoatrial node cardiac muscle cell action potential" ; oboInOwl:hasNarrowSynonym "sinus node cardiac muscle cell action potential" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086015" ; a owl:Class ; rdfs:label "SA node cell action potential" ; rdfs:subClassOf obo:GO_0086001, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0086018 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_1000409 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001508 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_1000409 ] ) ] . obo:GO_0086016 obo:IAO_0000115 "An action potential that occurs in an atrioventricular node cardiac muscle cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-10T08:58:56Z" ; oboInOwl:hasExactSynonym "AV node cardiac muscle cell action potential", "atrioventricular node cardiac muscle cell action potential" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086016" ; a owl:Class ; rdfs:label "AV node cell action potential" ; rdfs:subClassOf obo:GO_0086001, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0086027 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_1000410 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001508 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_1000410 ] ) ] . obo:GO_0086017 obo:IAO_0000115 "An action potential that occurs in a Purkinje myocyte." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-10T08:58:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086017" ; a owl:Class ; rdfs:label "Purkinje myocyte action potential" ; rdfs:subClassOf obo:GO_0086001, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0086029 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0002068 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001508 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0002068 ] ) ] . obo:GO_0086018 obo:IAO_0000115 "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-10T09:15:01Z" ; oboInOwl:hasExactSynonym "SA node cardiac muscle cell to atrial cardiac muscle cell signalling", "SA node cardiomyocyte to atrial cardiomyocyte signalling", "SAN cardiomyocyte to atrial cardiomyocyte signalling", "sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling" ; oboInOwl:hasNarrowSynonym "sinus node cardiomyocyte to atrial cardiomyocyte signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086018" ; a owl:Class ; rdfs:label "SA node cell to atrial cardiac muscle cell signaling" ; rdfs:subClassOf obo:GO_0086019, obo:GO_0086070 . obo:GO_0086019 obo:IAO_0000115 "Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-11-16T03:43:52Z" ; oboInOwl:hasExactSynonym "cell-cell signalling involved in cardiac conduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086019" ; a owl:Class ; rdfs:label "cell-cell signaling involved in cardiac conduction" ; rdfs:subClassOf obo:GO_0007267, obo:GO_0086065 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061337 ] ) ] . obo:GO_0086027 obo:IAO_0000115 "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-11T02:02:14Z" ; oboInOwl:hasExactSynonym "AV node cell to bundle of His cell signalling", "atrioventricular node to bundle of His cell signaling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086027" ; a owl:Class ; rdfs:label "AV node cell to bundle of His cell signaling" ; rdfs:subClassOf obo:GO_0086019, obo:GO_0086067 . obo:GO_0086029 obo:IAO_0000115 "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-11T02:02:14Z" ; oboInOwl:hasExactSynonym "Purkinje myocyte to ventricular cardiac muscle cell signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086029" ; a owl:Class ; rdfs:label "Purkinje myocyte to ventricular cardiac muscle cell signaling" ; rdfs:subClassOf obo:GO_0086019, obo:GO_0086068 . obo:GO_0086065 obo:IAO_0000115 "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-11-22T08:57:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086065" ; a owl:Class ; rdfs:label "cell communication involved in cardiac conduction" ; rdfs:subClassOf obo:GO_0007154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061337 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007154 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061337 ] ) ] . obo:GO_0086067 obo:IAO_0000115 "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-11-22T09:11:44Z" ; oboInOwl:hasExactSynonym "atrioventricular node cell to bundle of His cell communication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086067" ; a owl:Class ; rdfs:label "AV node cell to bundle of His cell communication" ; rdfs:subClassOf obo:GO_0086065 . obo:GO_0086068 obo:IAO_0000115 "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-11-22T09:14:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086068" ; a owl:Class ; rdfs:label "Purkinje myocyte to ventricular cardiac muscle cell communication" ; rdfs:subClassOf obo:GO_0086065 . obo:GO_0086070 obo:IAO_0000115 "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-11-22T09:32:45Z" ; oboInOwl:hasExactSynonym "SA node cardiac muscle cell to atrial cardiac muscle cell communication", "SA node cardiomyocyte to atrial cardiomyocyte communication", "SAN cardiomyocyte to atrial cardiomyocyte communication", "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication" ; oboInOwl:hasNarrowSynonym "sinus node cardiomyocyte to atrial cardiomyocyte communication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0086070" ; a owl:Class ; rdfs:label "SA node cell to atrial cardiac muscle cell communication" ; rdfs:subClassOf obo:GO_0086065 . obo:GO_0090009 obo:IAO_0000115 "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-07-29T10:31:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090009" ; a owl:Class ; rdfs:label "primitive streak formation" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001702 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009948 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004341 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048646 [ a owl:Restriction ; owl:onProperty obo:RO_0002297 ; owl:someValuesFrom obo:UBERON_0004341 ] ) ] . obo:GO_0090063 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-08-12T11:33:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090063" ; a owl:Class ; rdfs:label "positive regulation of microtubule nucleation" ; rdfs:subClassOf obo:GO_0010968, obo:GO_0031116, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007020 ] ) ] . obo:GO_0090066 obo:IAO_0000115 "Any process that modulates the size of an anatomical structure." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-02T11:00:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090066" ; a owl:Class ; rdfs:label "regulation of anatomical structure size" ; rdfs:subClassOf obo:GO_0065008 . obo:GO_0090068 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-09T11:39:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090068" ; a owl:Class ; rdfs:label "positive regulation of cell cycle process" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0045787, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022402 ] ) ] . obo:GO_0090069 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-11T10:32:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090069" ; a owl:Class ; rdfs:label "regulation of ribosome biogenesis" ; rdfs:subClassOf obo:GO_0044087, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042254 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042254 ] ) ] . obo:GO_0090070 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-11T10:32:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090070" ; a owl:Class ; rdfs:label "positive regulation of ribosome biogenesis" ; rdfs:subClassOf obo:GO_0044089, obo:GO_0090069, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042254 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042254 ] ) ] . obo:GO_0090071 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-11T10:32:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090071" ; a owl:Class ; rdfs:label "negative regulation of ribosome biogenesis" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0090069, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042254 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042254 ] ) ] . obo:GO_0090087 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-10-23T11:21:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090087" ; a owl:Class ; rdfs:label "regulation of peptide transport" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015833 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015833 ] ) ] . obo:GO_0090091 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-11-04T10:03:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090091" ; a owl:Class ; rdfs:label "positive regulation of extracellular matrix disassembly" ; rdfs:subClassOf obo:GO_0010715, obo:GO_1903055, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022617 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022617 ] ) ] . obo:GO_0090130 obo:IAO_0000115 "The process in which the population of cells that make up a tissue undergo directed movement." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-07T03:13:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090130" ; a owl:Class ; rdfs:label "tissue migration" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0090132 obo:IAO_0000115 "The process in which the population of cells that make up an epithelium undergo directed movement." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-07T03:19:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090132" ; a owl:Class ; rdfs:label "epithelium migration" ; rdfs:subClassOf obo:GO_0090130 . obo:GO_0090138 obo:IAO_0000115 "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T02:05:00Z" ; oboInOwl:hasExactSynonym "regulation of actin cytoskeleton organisation by cell-cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090138" ; a owl:Class ; rdfs:label "regulation of actin cytoskeleton organization by cell-cell adhesion" ; rdfs:subClassOf obo:GO_0032956, obo:GO_0098609 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098609 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030036 ] ) ] . obo:GO_0090139 obo:IAO_0000115 "A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T02:12:19Z" ; oboInOwl:hasExactSynonym "mitochondrial DNA packaging" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090139" ; a owl:Class ; rdfs:label "mitochondrial chromosome packaging" ; rdfs:subClassOf obo:GO_0051276, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051276 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0090148 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T03:06:36Z" ; oboInOwl:hasExactSynonym "membrane scission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090148" ; a owl:Class ; rdfs:label "membrane fission" ; rdfs:subClassOf obo:GO_0061024 . obo:GO_0090150 obo:IAO_0000115 "The directed movement of a protein to a specific location in a membrane." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T03:18:51Z" ; oboInOwl:hasExactSynonym "establishment of protein localisation in membrane", "establishment of protein localization in membrane" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090150" ; a owl:Class ; rdfs:label "establishment of protein localization to membrane" ; rdfs:subClassOf obo:GO_0045184, obo:GO_0072657 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045184 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0090162 obo:IAO_0000115 "The specification and formation of anisotropic intracellular organization of an epithelial cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T08:58:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090162" ; a owl:Class ; rdfs:label "establishment of epithelial cell polarity" ; rdfs:subClassOf obo:GO_0030010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000066 ] ) ] . obo:GO_0090166 obo:IAO_0000115 "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T09:15:11Z" ; oboInOwl:hasExactSynonym "Golgi apparatus disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090166" ; a owl:Class ; rdfs:label "Golgi disassembly" ; rdfs:subClassOf obo:GO_0007030, obo:GO_1903008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048313 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0005794 ] ) ] . obo:GO_0090168 obo:IAO_0000115 "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T09:15:11Z" ; oboInOwl:hasExactSynonym "Golgi apparatus reassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090168" ; a owl:Class ; rdfs:label "Golgi reassembly" ; rdfs:subClassOf obo:GO_0007030, obo:GO_0022607, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048313 ] . obo:GO_0090169 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-11T10:17:51Z" ; oboInOwl:hasExactSynonym "regulation of spindle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090169" ; a owl:Class ; rdfs:label "regulation of spindle assembly" ; rdfs:subClassOf obo:GO_0090224, obo:GO_1902115, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051225 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051225 ] ) ] . obo:GO_0090170 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-11T10:21:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090170" ; a owl:Class ; rdfs:label "regulation of Golgi inheritance" ; rdfs:subClassOf obo:GO_1903358, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048313 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048313 ] ) ] . obo:GO_0090171 obo:IAO_0000115 "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-11T10:36:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090171" ; a owl:Class ; rdfs:label "chondrocyte morphogenesis" ; rdfs:subClassOf obo:GO_0000904, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002063 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000138 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002299 ; owl:someValuesFrom obo:CL_0000138 ] ) ] . obo:GO_0090172 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-11T11:07:42Z" ; oboInOwl:hasExactSynonym "microtubule cytoskeleton organisation involved in homologous chromosome segregation", "microtubule organization involved in chromosome pairing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090172" ; a owl:Class ; rdfs:label "microtubule cytoskeleton organization involved in homologous chromosome segregation" ; rdfs:subClassOf obo:GO_0000226, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000226 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045143 ] ) ] . obo:GO_0090174 obo:IAO_0000115 "The joining of two lipid bilayers to form a single organelle membrane." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-11T11:44:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090174" ; a owl:Class ; rdfs:label "organelle membrane fusion" ; rdfs:subClassOf obo:GO_0048284, obo:GO_0061025, [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0031090 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061025 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0031090 ] ) ] . obo:GO_0090183 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-18T10:50:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of nephrogenesis" ; oboInOwl:id "GO:0090183" ; a owl:Class ; rdfs:label "regulation of kidney development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001822 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0090184 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-18T10:52:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of nephrogenesis" ; oboInOwl:id "GO:0090184" ; a owl:Class ; rdfs:label "positive regulation of kidney development" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0051240, obo:GO_0090183, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001822 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0090185 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-18T10:58:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of nephrogenesis" ; oboInOwl:id "GO:0090185" ; a owl:Class ; rdfs:label "negative regulation of kidney development" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0051241, obo:GO_0090183, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001822 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001822 ] ) ] . obo:GO_0090189 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-18T11:11:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090189" ; a owl:Class ; rdfs:label "regulation of branching involved in ureteric bud morphogenesis" ; rdfs:subClassOf obo:GO_0060688, obo:GO_0090183, obo:GO_1905330, obo:GO_2000027, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001658 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001658 ] ) ] . obo:GO_0090190 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-18T11:11:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090190" ; a owl:Class ; rdfs:label "positive regulation of branching involved in ureteric bud morphogenesis" ; rdfs:subClassOf obo:GO_0051240, obo:GO_0090189, obo:GO_1905332, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001658 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001658 ] ) ] . obo:GO_0090191 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-18T11:11:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090191" ; a owl:Class ; rdfs:label "negative regulation of branching involved in ureteric bud morphogenesis" ; rdfs:subClassOf obo:GO_0051241, obo:GO_0090189, obo:GO_1905331, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001658 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001658 ] ) ] . obo:GO_0090224 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-13T11:04:53Z" ; oboInOwl:hasExactSynonym "regulation of spindle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090224" ; a owl:Class ; rdfs:label "regulation of spindle organization" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0070507, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007051 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007051 ] ) ] . obo:GO_0090231 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-20T10:29:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090231" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc)." ; rdfs:label "regulation of spindle checkpoint" ; rdfs:subClassOf obo:GO_1901976, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031577 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031577 ] ) ] . obo:GO_0090232 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-20T10:29:43Z" ; oboInOwl:hasNarrowSynonym "spindle checkpoint activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090232" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:label "positive regulation of spindle checkpoint" ; rdfs:subClassOf obo:GO_0090231, obo:GO_1901978, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031577 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031577 ] ) ] . obo:GO_0090233 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-20T10:29:43Z" ; oboInOwl:hasNarrowSynonym "spindle checkpoint silencing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090233" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc)." ; rdfs:label "negative regulation of spindle checkpoint" ; rdfs:subClassOf obo:GO_0090231, obo:GO_1901977, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031577 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031577 ] ) ] . obo:GO_0090235 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-20T11:05:55Z" ; oboInOwl:hasExactSynonym "regulation of chromosome congression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090235" ; a owl:Class ; rdfs:label "regulation of metaphase plate congression" ; rdfs:subClassOf obo:GO_0032879, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051310 ] ) ] . obo:GO_0090257 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-03T11:48:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090257" ; a owl:Class ; rdfs:label "regulation of muscle system process" ; rdfs:subClassOf obo:GO_0044057, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003012 ] ) ] . obo:GO_0090266 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:06:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090266" ; a owl:Class ; rdfs:label "regulation of mitotic cell cycle spindle assembly checkpoint" ; rdfs:subClassOf obo:GO_0007088, obo:GO_0010965, obo:GO_0030071, obo:GO_0033047, obo:GO_1903504, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007094 ] ) ] . obo:GO_0090267 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:09:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090267" ; a owl:Class ; rdfs:label "positive regulation of mitotic cell cycle spindle assembly checkpoint" ; rdfs:subClassOf obo:GO_0090068, obo:GO_0090232, obo:GO_0090266, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007094 ] ) ] . obo:GO_0090273 obo:IAO_0000115 "Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:54:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090273" ; a owl:Class ; rdfs:label "regulation of somatostatin secretion" ; rdfs:subClassOf obo:GO_0090276, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070253 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070253 ] ) ] . obo:GO_0090274 obo:IAO_0000115 "Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:54:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090274" ; a owl:Class ; rdfs:label "positive regulation of somatostatin secretion" ; rdfs:subClassOf obo:GO_0090273, obo:GO_0090277, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070253 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070253 ] ) ] . obo:GO_0090275 obo:IAO_0000115 "Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:54:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090275" ; a owl:Class ; rdfs:label "negative regulation of somatostatin secretion" ; rdfs:subClassOf obo:GO_0090273, obo:GO_0090278, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070253 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070253 ] ) ] . obo:GO_0090276 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:56:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090276" ; a owl:Class ; rdfs:label "regulation of peptide hormone secretion" ; rdfs:subClassOf obo:GO_0002791, obo:GO_0046883, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030072 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030072 ] ) ] . obo:GO_0090277 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:56:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090277" ; a owl:Class ; rdfs:label "positive regulation of peptide hormone secretion" ; rdfs:subClassOf obo:GO_0002793, obo:GO_0046887, obo:GO_0090276, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030072 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030072 ] ) ] . obo:GO_0090278 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:56:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090278" ; a owl:Class ; rdfs:label "negative regulation of peptide hormone secretion" ; rdfs:subClassOf obo:GO_0002792, obo:GO_0046888, obo:GO_0090276, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030072 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030072 ] ) ] . obo:GO_0090282 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-09T02:13:26Z" ; oboInOwl:hasExactSynonym "activation of G2/M-specific transcription in the mitotic cell cycle", "activation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle", "activation of transcription involved in G2/M transition of mitotic cell cycle", "positive regulation of G2/M-specific transcription in the mitotic cell cycle", "positive regulation of transcription from RNA polymerase II promoter during G2/M-phase of the mitotic cell cycle", "up-regulation of G2/M-specific transcription in the mitotic cell cycle", "up-regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle", "up-regulation of transcription involved in G2/M transition of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090282" ; a owl:Class ; rdfs:label "positive regulation of transcription involved in G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0000117, obo:GO_0045944 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045893 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000086 ] ) ] . obo:GO_0090296 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-03-12T03:58:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of mitochondrial DNA synthesis" ; oboInOwl:id "GO:0090296" ; a owl:Class ; rdfs:label "regulation of mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0090329, obo:GO_1901858, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006264 ] ) ] . obo:GO_0090297 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-03-12T03:58:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of mitochondrial DNA synthesis" ; oboInOwl:id "GO:0090297" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0090296, obo:GO_1901860, obo:GO_2000105, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006264 ] ) ] . obo:GO_0090298 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-03-12T03:58:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of mitochondrial DNA synthesis" ; oboInOwl:id "GO:0090298" ; a owl:Class ; rdfs:label "negative regulation of mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0090296, obo:GO_1901859, obo:GO_2000104, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006264 ] ) ] . obo:GO_0090299 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-03-12T04:08:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090299" ; a owl:Class ; rdfs:label "regulation of neural crest formation" ; rdfs:subClassOf obo:GO_0010717, obo:GO_0022603, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014029 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0014029 ] ) ] . obo:GO_0090300 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-03-12T04:08:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090300" ; a owl:Class ; rdfs:label "positive regulation of neural crest formation" ; rdfs:subClassOf obo:GO_0010718, obo:GO_0090299, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014029 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0014029 ] ) ] . obo:GO_0090301 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-03-12T04:08:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090301" ; a owl:Class ; rdfs:label "negative regulation of neural crest formation" ; rdfs:subClassOf obo:GO_0010719, obo:GO_0090299, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014029 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0014029 ] ) ] . obo:GO_0090304 obo:IAO_0000115 "Any cellular metabolic process involving nucleic acids." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-07T10:18:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090304" ; a owl:Class ; rdfs:label "nucleic acid metabolic process" ; rdfs:subClassOf obo:GO_0006139, obo:GO_0043170, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33696 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_33696 ] ) ] . obo:GO_0090306 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21349"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/24375"^^xsd:anyURI ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-09T11:21:56Z" ; oboInOwl:hasExactSynonym "spindle assembly involved in meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090306" ; a owl:Class ; rdfs:label "meiotic spindle assembly" ; rdfs:subClassOf obo:GO_0000212, obo:GO_0051225, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045132 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0090307 obo:IAO_0000115 "Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24375"^^xsd:anyURI ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-09T11:31:28Z" ; oboInOwl:hasExactSynonym "spindle assembly involved in mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090307" ; a owl:Class ; rdfs:label "mitotic spindle assembly" ; rdfs:subClassOf obo:GO_0007052, obo:GO_0051225, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0090316 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-16T03:45:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090316" ; a owl:Class ; rdfs:label "positive regulation of intracellular protein transport" ; rdfs:subClassOf obo:GO_0032388, obo:GO_0033157, obo:GO_0051222, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006886 ] ) ] . obo:GO_0090317 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-16T03:45:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090317" ; a owl:Class ; rdfs:label "negative regulation of intracellular protein transport" ; rdfs:subClassOf obo:GO_0032387, obo:GO_0033157, obo:GO_0051224, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006886 ] ) ] . obo:GO_0090325 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-05-14T10:24:29Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090325" ; a owl:Class ; rdfs:label "regulation of locomotion involved in locomotory behavior" ; rdfs:subClassOf obo:GO_0040012, obo:GO_0050795, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031987 ] ) ] . obo:GO_0090326 obo:IAO_0000115 "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-05-14T10:26:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090326" ; a owl:Class ; rdfs:label "positive regulation of locomotion involved in locomotory behavior" ; rdfs:subClassOf obo:GO_0040017, obo:GO_0048520, obo:GO_0090325, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050789 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031987 ] ) ] . obo:GO_0090327 obo:IAO_0000115 "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-05-14T10:26:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090327" ; a owl:Class ; rdfs:label "negative regulation of locomotion involved in locomotory behavior" ; rdfs:subClassOf obo:GO_0040013, obo:GO_0048521, obo:GO_0090325, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031987 ] ) ] . obo:GO_0090329 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-05-14T10:42:04Z" ; oboInOwl:hasExactSynonym "regulation of DNA-dependent DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090329" ; a owl:Class ; rdfs:label "regulation of DNA-templated DNA replication" ; rdfs:subClassOf obo:GO_0006275, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006261 ] ) ] . obo:GO_0090419 obo:IAO_0000115 "Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-10-26T03:59:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down-regulation of transcription from RNA polymerase II promoter during the G2/M transition of the mitotic cell cycle", "negative regulation of transcription from RNA polymerase II promoter during G2/M transition of the mitotic cell cycle" ; oboInOwl:id "GO:0090419" ; a owl:Class ; rdfs:label "negative regulation of transcription involved in G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0000117, obo:GO_0045892 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045892 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000086 ] ) ] . obo:GO_0090425 obo:IAO_0000115 "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2012-05-04T09:24:48Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090425" ; a owl:Class ; rdfs:label "acinar cell differentiation" ; rdfs:subClassOf obo:GO_0002067, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000622 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000622 ] ) ] . obo:GO_0090435 obo:IAO_0000115 "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2012-07-30T01:50:41Z" ; oboInOwl:hasExactSynonym "protein localization in nuclear envelope" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090435" ; a owl:Class ; rdfs:label "protein localization to nuclear envelope" ; rdfs:subClassOf obo:GO_0034504, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005635 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005635 ] ) ] . obo:GO_0090493 obo:IAO_0000115 "The directed movement of catecholamine into a cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2012-10-17T11:06:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090493" ; a owl:Class ; rdfs:label "catecholamine uptake" ; rdfs:subClassOf obo:GO_0051937, obo:GO_0098657 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005576 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_33567 ] ) ] . obo:GO_0090494 obo:IAO_0000115 "The directed movement of dopamine into a cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2012-10-17T11:12:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090494" ; a owl:Class ; rdfs:label "dopamine uptake" ; rdfs:subClassOf obo:GO_0015872, obo:GO_0098657 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005576 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_59905 ] ) ] . obo:GO_0090497 obo:IAO_0000115 "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2012-10-17T12:08:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090497" ; a owl:Class ; rdfs:label "mesenchymal cell migration" ; rdfs:subClassOf obo:GO_0001667, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0008019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0008019 ] ) ] . obo:GO_0090527 obo:IAO_0000115 "A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2013-01-23T10:27:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090527" ; a owl:Class ; rdfs:label "actin filament reorganization" ; rdfs:subClassOf obo:GO_0007015, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031532 ] . obo:GO_0090592 obo:IAO_0000115 "Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2014-06-06T13:54:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090592" ; a owl:Class ; rdfs:label "DNA synthesis involved in DNA replication" ; rdfs:subClassOf obo:GO_0071897, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071897 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006260 ] ) ] . obo:GO_0090596 obo:IAO_0000115 "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2014-08-22T13:23:20Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090596" ; a owl:Class ; rdfs:label "sensory organ morphogenesis" ; rdfs:subClassOf obo:GO_0009887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007423 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0000020 ] ) ] . obo:GO_0090598 obo:IAO_0000115 "The processes by which anatomical structures that are only present in the male organism are generated and organized." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2014-08-22T13:29:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090598" ; a owl:Class ; rdfs:label "male anatomical structure morphogenesis" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046661 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0014403 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0014403 ] ) ] . obo:GO_0090615 obo:IAO_0000115 "Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2014-10-24T12:43:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090615" ; a owl:Class ; rdfs:label "mitochondrial mRNA processing" ; rdfs:subClassOf obo:GO_0000963, obo:GO_0006397 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006397 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0090664 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2015-10-21T16:00:30Z" ; oboInOwl:hasExactSynonym "response to crowding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090664" ; a owl:Class ; rdfs:label "response to high population density" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0032501 . obo:GO_0090685 obo:IAO_0000115 "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2016-07-19T17:00:49Z" ; oboInOwl:hasExactSynonym "RNA localisation to nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090685" ; a owl:Class ; rdfs:label "RNA localization to nucleus" ; rdfs:subClassOf obo:GO_0006403, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006403 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0090727 obo:IAO_0000115 "Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2016-12-19T15:07:32Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090727" ; a owl:Class ; rdfs:label "positive regulation of brood size" ; rdfs:subClassOf obo:GO_0060378, [ a owl:Restriction ; owl:onProperty obo:RO_0019001 ; owl:someValuesFrom obo:PATO_0000276 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0019001 ; owl:someValuesFrom obo:PATO_0000276 ] ) ] . obo:GO_0090728 obo:IAO_0000115 "Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2016-12-19T15:07:32Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090728" ; a owl:Class ; rdfs:label "negative regulation of brood size" ; rdfs:subClassOf obo:GO_0060378, [ a owl:Restriction ; owl:onProperty obo:RO_0019002 ; owl:someValuesFrom obo:PATO_0000276 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0019002 ; owl:someValuesFrom obo:PATO_0000276 ] ) ] . obo:GO_0090741 obo:IAO_0000115 "Any membrane that is part of a pigment granule." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2017-05-16T22:33:39Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0090741" ; a owl:Class ; rdfs:label "pigment granule membrane" ; rdfs:subClassOf obo:GO_0030659, obo:GO_0098588, [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0048770 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0048770 ] ) ] . obo:GO_0097014 obo:IAO_0000115 "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-03-23T01:52:31Z" ; oboInOwl:hasExactSynonym "cilium plasm" ; oboInOwl:hasNarrowSynonym "microtubule-based flagellar matrix", "microtubule-based flagellum matrix" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cilial cytoplasm", "ciliary cytoplasm", "cilium cytoplasm", "microtubule-based flagellar cytoplasm", "microtubule-based flagellum cytoplasm" ; oboInOwl:id "GO:0097014" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term \"ciliary plasm\" is not linked to \"cytoplasm\"." ; rdfs:label "ciliary plasm" ; rdfs:subClassOf obo:GO_0032838, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005929 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:GO_0097026 obo:IAO_0000115 "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-03-31T04:52:53Z" ; oboInOwl:hasBroadSynonym "dendritic extension" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097026" ; a owl:Class ; rdfs:comment "Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals." ; rdfs:label "dendritic cell dendrite assembly" ; rdfs:subClassOf obo:GO_0120031, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0097511 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0097511 ] ) ] . obo:GO_0097028 obo:IAO_0000115 "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-04-01T10:08:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097028" ; a owl:Class ; rdfs:comment "Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'." ; rdfs:label "dendritic cell differentiation" ; rdfs:subClassOf obo:GO_1903131, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000451 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000451 ] ) ] . obo:GO_0097048 obo:IAO_0000115 "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-05-04T02:18:59Z" ; oboInOwl:hasNarrowSynonym "dendritic cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097048" ; a owl:Class ; rdfs:label "dendritic cell apoptotic process" ; rdfs:subClassOf obo:GO_0071887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000451 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000451 ] ) ] . obo:GO_0097049 obo:IAO_0000115 "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-05-04T02:21:43Z" ; oboInOwl:hasExactSynonym "motoneuron apoptosis" ; oboInOwl:hasNarrowSynonym "motor neuron apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097049" ; a owl:Class ; rdfs:label "motor neuron apoptotic process" ; rdfs:subClassOf obo:GO_0051402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000100 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000100 ] ) ] . obo:GO_0097050 obo:IAO_0000115 "Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-05-04T02:24:38Z" ; oboInOwl:hasExactSynonym "pancreatic B cell apoptosis", "pancreatic beta cell apoptosis" ; oboInOwl:hasNarrowSynonym "type B pancreatic cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097050" ; a owl:Class ; rdfs:label "type B pancreatic cell apoptotic process" ; rdfs:subClassOf obo:GO_1904019, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000169 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000169 ] ) ] . obo:GO_0097060 obo:IAO_0000115 "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-06-07T11:22:09Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097060" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic membrane" ; rdfs:subClassOf obo:GO_0098590, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098590 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0097084 obo:IAO_0000115 "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-06-20T04:03:08Z" ; oboInOwl:hasExactSynonym "vascular smooth muscle cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097084" ; a owl:Class ; rdfs:label "vascular associated smooth muscle cell development" ; rdfs:subClassOf obo:GO_0055001, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0035886 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000359 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0000359 ] ) ] . obo:GO_0097091 obo:IAO_0000115 "The process that results in grouping synaptic vesicles in presynaptic structures." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/163"^^xsd:anyURI ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-07-04T01:48:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097091" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle clustering" ; rdfs:subClassOf obo:GO_0097479, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099504 ] . obo:GO_0097152 obo:IAO_0000115 "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-09-06T02:31:59Z" ; oboInOwl:hasNarrowSynonym "mesenchymal cell apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097152" ; a owl:Class ; rdfs:label "mesenchymal cell apoptotic process" ; rdfs:subClassOf obo:GO_0006915, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0008019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0008019 ] ) ] . obo:GO_0097154 obo:IAO_0000115 "The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-09-14T09:39:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097154" ; a owl:Class ; rdfs:label "GABAergic neuron differentiation" ; rdfs:subClassOf obo:GO_0030182, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000617 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0000617 ] ) ] . obo:GO_0097159 obo:IAO_0000115 "Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-09-23T02:31:01Z" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0097159" ; a owl:Class ; rdfs:label "organic cyclic compound binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33832 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_33832 ] ) ] . obo:GO_0097164 obo:IAO_0000115 "The chemical reactions and pathways involving the ammonium ion." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-09-28T04:21:30Z" ; oboInOwl:hasExactSynonym "ammonium ion metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ammonium metabolic process" ; oboInOwl:id "GO:0097164" ; a owl:Class ; rdfs:label "ammonium ion metabolic process" ; rdfs:subClassOf obo:GO_0006807, [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_28938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:RO_0004007 ; owl:someValuesFrom obo:CHEBI_28938 ] ) ] . obo:GO_0097190 obo:IAO_0000115 "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-23T09:30:23Z" ; oboInOwl:hasAlternativeId "GO:0008624" ; oboInOwl:hasExactSynonym "apoptotic signalling pathway", "induction of apoptosis by extracellular signals" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097190" ; a owl:Class ; rdfs:comment "This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways." ; rdfs:label "apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_0007165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006915 ] . obo:GO_0097193 obo:IAO_0000115 "The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP)." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-23T09:40:50Z" ; oboInOwl:hasAlternativeId "GO:0008629" ; oboInOwl:hasExactSynonym "intrinsic apoptotic pathway", "intrinsic apoptotic signalling pathway", "mitochondrial-mediated apoptotic pathway" ; oboInOwl:hasNarrowSynonym "intrinsic apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "induction of apoptosis by intracellular signals" ; oboInOwl:id "GO:0097193" ; a owl:Class ; rdfs:comment "The signals that start intrinsic apoptosis may come from extracellular sources (e.g. oxidative stress, UV exposure), but the reception of the signal and thus the signaling pathway start inside the cell (as a result of DNA damage, redox imbalance, etc.). Examples are ZPR9 (ZNF622) and ASK1 (MAP3K5) (UniProt symbols Q969S3 and Q99683) in PMID:21771788. A diagram of the intrinsic apoptotic pathway including examples of molecular players can be found in Figure 2 in PMID:21760595." ; rdfs:label "intrinsic apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_0035556, obo:GO_0097190 . obo:GO_0097194 obo:IAO_0000115 "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-23T09:45:24Z" ; oboInOwl:hasExactSynonym "execution phase of apoptotic process" ; oboInOwl:hasNarrowSynonym "apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097194" ; a owl:Class ; rdfs:label "execution phase of apoptosis" ; rdfs:subClassOf obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006915 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0032060 ] . obo:GO_0097212 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-01-12T10:16:15Z" ; oboInOwl:hasExactSynonym "lysosomal membrane organisation", "lysosome membrane organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097212" ; a owl:Class ; rdfs:label "lysosomal membrane organization" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007040 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005765 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0005765 ] ) ] . obo:GO_0097237 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-02-02T12:23:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097237" ; a owl:Class ; rdfs:label "cellular response to toxic substance" . obo:GO_0097254 obo:IAO_0000115 "The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22368"^^xsd:anyURI ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-03-05T02:03:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097254" ; a owl:Class ; rdfs:label "renal tubular secretion" ; rdfs:subClassOf obo:GO_0003014, obo:GO_0007588 . obo:GO_0097272 obo:IAO_0000115 "Any biological process involved in the maintenance of an internal steady state of ammonium." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-03-22T02:51:22Z" ; oboInOwl:hasExactSynonym "ammonia homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097272" ; a owl:Class ; rdfs:label "ammonium homeostasis" ; rdfs:subClassOf obo:GO_0098771, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_28938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048878 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_28938 ] ) ] . obo:GO_0097275 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-03-22T02:54:38Z" ; oboInOwl:hasExactSynonym "cellular ammonia homeostasis", "cellular ammonium homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097275" ; a owl:Class ; rdfs:label "intracellular ammonium homeostasis" ; rdfs:subClassOf obo:GO_0055082, obo:GO_0097272 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0055082 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_28938 ] ) ] . obo:GO_0097284 obo:IAO_0000115 "Any apoptotic process in a hepatocyte, the main structural component of the liver." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-03-29T10:23:21Z" ; oboInOwl:hasNarrowSynonym "hepatocyte apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097284" ; a owl:Class ; rdfs:label "hepatocyte apoptotic process" ; rdfs:subClassOf obo:GO_1904019, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000182 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000182 ] ) ] . obo:GO_0097355 obo:IAO_0000115 "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-07-03T03:19:07Z" ; oboInOwl:hasExactSynonym "protein localisation to heterochromatin" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097355" ; a owl:Class ; rdfs:label "protein localization to heterochromatin" ; rdfs:subClassOf obo:GO_0071168, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0000792 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0000792 ] ) ] . obo:GO_0097360 obo:IAO_0000115 "The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-07-19T10:17:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097360" ; a owl:Class ; rdfs:label "chorionic trophoblast cell proliferation" ; rdfs:subClassOf obo:GO_0008283, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0011101 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0011101 ] ) ] . obo:GO_0097367 obo:IAO_0000115 "Binding to a carbohydrate derivative." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-08-02T13:03:39Z" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0097367" ; oboInOwl:inSubset go:goslim_agr, go:goslim_mouse ; a owl:Class ; rdfs:label "carbohydrate derivative binding" ; rdfs:subClassOf obo:GO_0005488, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_63299 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_63299 ] ) ] . obo:GO_0097386 obo:IAO_0000115 "A prolongation or process extending from a glial cell." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-10-22T13:55:54Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "glial process", "glial projection" ; oboInOwl:id "GO:0097386" ; a owl:Class ; rdfs:label "glial cell projection" ; rdfs:subClassOf obo:GO_0120025, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0120025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000125 ] ) ] . obo:GO_0097402 obo:IAO_0000115 "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-10-29T08:24:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097402" ; a owl:Class ; rdfs:label "neuroblast migration" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000031 ] ) ] . obo:GO_0097427 obo:IAO_0000115 "An arrangement of closely apposed microtubules running parallel to each other." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-07T15:01:27Z" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1872343973" ; oboInOwl:hasExactSynonym "microtubule fascicle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097427" ; a owl:Class ; rdfs:label "microtubule bundle" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005856 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005874 ] . obo:GO_0097435 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-27T15:46:25Z" ; oboInOwl:hasAlternativeId "GO:0043206" ; oboInOwl:hasNarrowSynonym "extracellular fibril organisation", "extracellular fibril organization", "extracellular fibril organization and biogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "fibril organisation", "fibril organization" ; oboInOwl:id "GO:0097435" ; a owl:Class ; rdfs:label "supramolecular fiber organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0099512 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0099512 ] ) ] . obo:GO_0097447 obo:IAO_0000115 "The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-12-17T12:31:49Z" ; oboInOwl:hasDbXref "NIF_Subcellular:sao172297168" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097447" ; a owl:Class ; rdfs:label "dendritic tree" ; rdfs:subClassOf obo:GO_0043005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0036477 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030425 ] . obo:GO_0097473 obo:IAO_0000115 "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-03-21T09:44:45Z" ; oboInOwl:hasExactSynonym "rod photoreceptor apoptotic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097473" ; a owl:Class ; rdfs:label "retinal rod cell apoptotic process" ; rdfs:subClassOf obo:GO_0051402, obo:GO_1990009, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000604 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000604 ] ) ] . obo:GO_0097474 obo:IAO_0000115 "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-03-21T09:46:22Z" ; oboInOwl:hasExactSynonym "cone photoreceptor apoptotic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097474" ; a owl:Class ; rdfs:label "retinal cone cell apoptotic process" ; rdfs:subClassOf obo:GO_0051402, obo:GO_1990009, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000573 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:CL_0000573 ] ) ] . obo:GO_0097475 obo:IAO_0000115 "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-04-23T13:00:46Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097475" ; a owl:Class ; rdfs:label "motor neuron migration" ; rdfs:subClassOf obo:GO_0001764, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000100 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000100 ] ) ] . obo:GO_0097476 obo:IAO_0000115 "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-04-23T13:03:46Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097476" ; a owl:Class ; rdfs:label "spinal cord motor neuron migration" ; rdfs:subClassOf obo:GO_0097475, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0011001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0011001 ] ) ] . obo:GO_0097479 obo:IAO_0000115 "Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-05-22T14:29:55Z" ; oboInOwl:hasExactSynonym "establishment and maintenance of synaptic vesicle localization", "establishment and maintenance of synaptic vesicle position", "synaptic vesicle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097479" ; a owl:Class ; rdfs:label "synaptic vesicle localization" ; rdfs:subClassOf obo:GO_0051648 . obo:GO_0097485 obo:IAO_0000115 "The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-07-08T13:32:37Z" ; oboInOwl:hasExactSynonym "neuron process guidance", "neuron protrusion guidance", "neuronal cell projection guidance" ; oboInOwl:hasNarrowSynonym "neurite guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097485" ; a owl:Class ; rdfs:label "neuron projection guidance" ; rdfs:subClassOf obo:GO_0031175, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006935 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048812 ] . obo:GO_0097511 obo:IAO_0000115 "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-10-16T13:02:25Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097511" ; a owl:Class ; rdfs:label "dendritic cell dendrite" ; rdfs:subClassOf obo:GO_0120025, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000451 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0120025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000451 ] ) ] . obo:GO_0097512 obo:IAO_0000115 "A cardiac myofibril is a myofibril specific to cardiac muscle cells." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-10-16T13:04:58Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097512" ; a owl:Class ; rdfs:label "cardiac myofibril" ; rdfs:subClassOf obo:GO_0030016, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000746 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030016 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000746 ] ) ] . obo:GO_0097524 obo:IAO_0000115 "A plasma membrane that is part of a sperm cell." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-10-18T11:31:17Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097524" ; a owl:Class ; rdfs:label "sperm plasma membrane" ; rdfs:subClassOf obo:GO_0005886, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005886 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000019 ] ) ] . obo:GO_0097529 obo:IAO_0000115 "The movement of a myeloid leukocyte within or between different tissues and organs of the body." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-11-11T13:59:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097529" ; a owl:Class ; rdfs:label "myeloid leukocyte migration" ; rdfs:subClassOf obo:GO_0050900, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000766 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000766 ] ) ] . obo:GO_0097534 obo:IAO_0000115 "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-11-28T10:47:15Z" ; oboInOwl:hasExactSynonym "lymphoid lineage restricted progenitor cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097534" ; a owl:Class ; rdfs:label "lymphoid lineage cell migration" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000838 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000838 ] ) ] . obo:GO_0097576 obo:IAO_0000115 "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2014-02-28T09:49:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097576" ; a owl:Class ; rdfs:label "vacuole fusion" ; rdfs:subClassOf obo:GO_0007033, obo:GO_0048284, [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0097708 obo:IAO_0000115 "Any vesicle that is part of the intracellular region." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-03-29T17:39:45Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097708" ; a owl:Class ; rdfs:label "intracellular vesicle" ; rdfs:subClassOf obo:GO_0031982, obo:GO_0043231 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031982 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0097711 obo:IAO_0000115 "The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-08-05T16:12:33Z" ; oboInOwl:hasDbXref "Reactome:R-HSA-5620912.1" ; oboInOwl:hasExactSynonym "ciliary basal body docking" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "anchoring of the basal body to the plasma membrane" ; oboInOwl:id "GO:0097711" ; a owl:Class ; rdfs:comment "Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella." ; rdfs:label "ciliary basal body-plasma membrane docking" ; rdfs:subClassOf obo:GO_0140056, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060271 ] . obo:GO_0097712 obo:IAO_0000115 "The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-08-05T16:16:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097712" ; a owl:Class ; rdfs:label "vesicle targeting, trans-Golgi to periciliary membrane compartment" ; rdfs:subClassOf obo:GO_0048199, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060271 ] . obo:GO_0097722 obo:IAO_0000115 "Any process involved in the controlled movement of a sperm cell." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-09-01T12:00:45Z" ; oboInOwl:hasExactSynonym "sperm movement" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097722" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "sperm motility" ; rdfs:subClassOf obo:GO_0022414, obo:GO_0048870, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048870 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0000019 ] ) ] . obo:GO_0097734 obo:IAO_0000115 "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-10-03T14:35:25Z" ; oboInOwl:hasExactSynonym "exosome assembly or secretion", "exosome biogenesis", "exosome production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ILV assembly", "intraluminal vesicle assembly" ; oboInOwl:id "GO:0097734" ; a owl:Class ; rdfs:label "extracellular exosome biogenesis" ; rdfs:subClassOf obo:GO_0140112 . obo:GO_0098523 obo:IAO_0000115 "A neuromuscular junction in which the target muscle cell is a myotube." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2013-10-14T12:05:12Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098523" ; a owl:Class ; rdfs:comment "In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes." ; rdfs:label "neuromuscular junction of myotube" ; rdfs:subClassOf obo:GO_0031594, [ a owl:Restriction ; owl:onProperty obo:RO_0002131 ; owl:someValuesFrom obo:CL_0002372 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045202 [ a owl:Restriction ; owl:onProperty obo:RO_0002131 ; owl:someValuesFrom obo:CL_0000100 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002131 ; owl:someValuesFrom obo:CL_0002372 ] ) ] . obo:GO_0098528 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2013-10-15T14:00:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098528" ; a owl:Class ; rdfs:label "skeletal muscle fiber differentiation" ; rdfs:subClassOf obo:GO_0014902, obo:GO_0035914, [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0008002 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030154 [ a owl:Restriction ; owl:onProperty obo:RO_0002315 ; owl:someValuesFrom obo:CL_0008002 ] ) ] . obo:GO_0098542 obo:IAO_0000115 "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22173"^^xsd:anyURI ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2013-11-11T12:59:11Z" ; oboInOwl:hasAlternativeId "GO:0009814" ; oboInOwl:hasNarrowSynonym "defence response incompatible interaction", "defence response to pathogen, incompatible interaction", "defense response, incompatible interaction", "resistance response to pathogen" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098542" ; oboInOwl:inSubset go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "defense response to other organism" ; rdfs:subClassOf obo:GO_0006952, obo:GO_0051707 . obo:GO_0098588 obo:IAO_0000115 "The lipid bilayer that forms the outer-most layer of an organelle." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2014-02-26T13:41:31Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098588" ; a owl:Class ; rdfs:comment "Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes." ; rdfs:label "bounding membrane of organelle" ; rdfs:subClassOf obo:GO_0031090, [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0098590 obo:IAO_0000115 "A membrane that is a (regional) part of the plasma membrane." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2014-03-06T11:55:32Z" ; oboInOwl:hasExactSynonym "region of plasma membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098590" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass." ; rdfs:label "plasma membrane region" ; rdfs:subClassOf obo:GO_0016020, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0098609 obo:IAO_0000115 "The attachment of one cell to another cell via adhesion molecules." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2014-04-16T13:40:03Z" ; oboInOwl:hasAlternativeId "GO:0016337" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organismal cell-cell adhesion" ; oboInOwl:id "GO:0098609" ; a owl:Class ; rdfs:label "cell-cell adhesion" ; rdfs:subClassOf obo:GO_0007155 . obo:GO_0098631 obo:IAO_0000115 "The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22959"^^xsd:anyURI ; oboInOwl:hasExactSynonym "cell adhesion molecule", "protein binding involved in cell adhesion" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0098631" ; oboInOwl:inSubset go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "cell adhesion mediator activity" ; rdfs:subClassOf obo:GO_0050839, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007155 ] ) ] . obo:GO_0098632 obo:IAO_0000115 "The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell." ; oboInOwl:hasExactSynonym "cell-cell adhesion molecule", "protein binding involved in cell-cell adhesion" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0098632" ; a owl:Class ; rdfs:label "cell-cell adhesion mediator activity" ; rdfs:subClassOf obo:GO_0098631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098609 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005515 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0098633 obo:IAO_0000115 "Binding to a collagen fibril." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0098633" ; a owl:Class ; rdfs:label "collagen fibril binding" ; rdfs:subClassOf obo:GO_0044877, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0098643 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:GO_0098643 ] ) ] . obo:GO_0098635 obo:IAO_0000115 "Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098635" ; a owl:Class ; rdfs:label "protein complex involved in cell-cell adhesion" ; rdfs:subClassOf obo:GO_0098636, [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0098609 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0098636 obo:IAO_0000115 "Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell." ; oboInOwl:hasAlternativeId "GO:1990307" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cell adhesion complex" ; oboInOwl:id "GO:0098636" ; a owl:Class ; rdfs:label "protein complex involved in cell adhesion" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0007155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0007155 ] ) ] . obo:GO_0098641 obo:IAO_0000115 "Any cadherin binding that occurs as part of the process of cell-cell adhesion." ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0098641" ; a owl:Class ; rdfs:label "cadherin binding involved in cell-cell adhesion" ; rdfs:subClassOf obo:GO_0045296, obo:GO_0098632 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045296 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0098642 obo:IAO_0000115 "A collagen trimer that forms networks." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098642" ; a owl:Class ; rdfs:label "network-forming collagen trimer" ; rdfs:subClassOf obo:GO_0005581, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098645 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005581 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098645 ] ) ] . obo:GO_0098643 obo:IAO_0000115 "A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098643" ; a owl:Class ; rdfs:label "banded collagen fibril" ; rdfs:subClassOf obo:GO_0098644, obo:GO_0099512 . obo:GO_0098644 obo:IAO_0000115 "A complex of collagen trimers such as a fibril or collagen network." ; oboInOwl:hasExactSynonym "Supramolecular aggregate of collagen", "Supramolecular collagen assembly" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098644" ; a owl:Class ; rdfs:label "complex of collagen trimers" ; rdfs:subClassOf obo:GO_0099080, obo:PR_000050567, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0062023 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005581 ] . obo:GO_0098645 obo:IAO_0000115 "A supramolecular complex that consists of collagen triple helices associated to form a network." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098645" ; a owl:Class ; rdfs:label "collagen network" ; rdfs:subClassOf obo:GO_0098644, obo:GO_0099081 . obo:GO_0098651 obo:IAO_0000115 "Any collagen timer that is part of a basement membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098651" ; a owl:Class ; rdfs:label "basement membrane collagen trimer" ; rdfs:subClassOf obo:GO_0005581, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005604 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005581 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005604 ] ) ] . obo:GO_0098655 obo:IAO_0000115 "The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom." ; oboInOwl:hasAlternativeId "GO:0099132" ; oboInOwl:hasBroadSynonym "cation transmembrane transport" ; oboInOwl:hasNarrowSynonym "ATP hydrolysis coupled cation transmembrane transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098655" ; a owl:Class ; rdfs:label "monoatomic cation transmembrane transport" ; rdfs:subClassOf obo:GO_0006812, obo:GO_0034220 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_23906 ] ) ] . obo:GO_0098657 obo:IAO_0000115 "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." ; oboInOwl:hasBroadSynonym "uptake" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098657" ; a owl:Class ; rdfs:label "import into cell" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005576 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005622 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005737 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24431 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005576 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24431 ] ) ], [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0005576 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005737 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24431 ] ) ] . obo:GO_0098660 obo:IAO_0000115 "The process in which an inorganic ion is transported across a membrane." ; oboInOwl:hasExactSynonym "inorganic ion membrane transport", "transmembrane inorganic ion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098660" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "inorganic ion transmembrane transport" ; rdfs:subClassOf obo:GO_0055085, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36914 ] ) ] . obo:GO_0098661 obo:IAO_0000115 "The process in which an inorganic anion is transported across a membrane." ; oboInOwl:hasExactSynonym "inorganic anion membrane transport", "transmembrane inorganic anion transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098661" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "inorganic anion transmembrane transport" ; rdfs:subClassOf obo:GO_0015698, obo:GO_0098660 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_24834 ] ) ] . obo:GO_0098662 obo:IAO_0000115 "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore." ; oboInOwl:hasAlternativeId "GO:0015672", "GO:0072511" ; oboInOwl:hasExactSynonym "inorganic cation membrane transport", "transmembrane inorganic cation transport" ; oboInOwl:hasNarrowSynonym "divalent inorganic cation transport", "monovalent inorganic cation transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098662" ; a owl:Class ; rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes." ; rdfs:label "inorganic cation transmembrane transport" ; rdfs:subClassOf obo:GO_0098660, [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002342 ; owl:someValuesFrom obo:GO_0016020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36915 ] ) ] . obo:GO_0098687 obo:IAO_0000115 "Any subdivision of a chromosome along its length." ; oboInOwl:hasExactSynonym "chromosome region" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098687" ; a owl:Class ; rdfs:comment "Chromosomal regions include parts that are not part of the chromatin. Examples include the kinetochore." ; rdfs:label "chromosomal region" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005694 ] . obo:GO_0098691 obo:IAO_0000115 "A synapse that uses dopamine as a neurotransmitter." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-03-07T14:51:52Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098691" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "dopaminergic synapse" ; rdfs:subClassOf obo:GO_0045202, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001963 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045202 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0001963 ] ) ] . obo:GO_0098693 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-03-21T16:06:48Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098693" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of synaptic vesicle cycle" ; rdfs:subClassOf obo:GO_0060627, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099504 ] ) ] . obo:GO_0098722 obo:IAO_0000115 "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098722" ; a owl:Class ; rdfs:label "asymmetric stem cell division" ; rdfs:subClassOf obo:GO_0008356, obo:GO_0017145 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008356 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000034 ] ) ] . obo:GO_0098723 obo:IAO_0000115 "A myofibril of a skeletal muscle fiber." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098723" ; a owl:Class ; rdfs:label "skeletal muscle myofibril" ; rdfs:subClassOf obo:GO_0030016, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0008002 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030016 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0008002 ] ) ] . obo:GO_0098727 obo:IAO_0000115 "Any process by which the numbers of cells of a particular type or in a tissue are maintained." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098727" ; a owl:Class ; rdfs:label "maintenance of cell number" ; rdfs:subClassOf obo:GO_0032502 . obo:GO_0098728 obo:IAO_0000115 "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098728" ; a owl:Class ; rdfs:label "germline stem cell asymmetric division" ; rdfs:subClassOf obo:GO_0042078, obo:GO_0098722 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008356 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CL_0000014 ] ) ] . obo:GO_0098751 obo:IAO_0000115 "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098751" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development." ; rdfs:label "bone cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060348 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0001035 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:CL_0001035 ] ) ] . obo:GO_0098754 obo:IAO_0000115 "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098754" ; oboInOwl:inSubset go:goslim_generic, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "detoxification" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009636 ] . obo:GO_0098762 obo:IAO_0000115 "One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098762" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiotic cell cycle phase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022403 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0098763 obo:IAO_0000115 "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098763" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "mitotic cell cycle phase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022403 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0098764 obo:IAO_0000115 "A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098764" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiosis I cell cycle phase" ; rdfs:subClassOf obo:GO_0098762 . obo:GO_0098771 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098771" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "inorganic ion homeostasis" ; rdfs:subClassOf obo:GO_0048878, [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_36914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042592 [ a owl:Restriction ; owl:onProperty obo:RO_0002332 ; owl:someValuesFrom obo:CHEBI_36914 ] ) ] . obo:GO_0098773 obo:IAO_0000115 "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098773" ; a owl:Class ; rdfs:label "skin epidermis development" ; rdfs:subClassOf obo:GO_0008544, obo:GO_0060429, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043588 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048856 [ a owl:Restriction ; owl:onProperty obo:RO_0002296 ; owl:someValuesFrom obo:UBERON_0001003 ] ) ] . obo:GO_0098793 obo:IAO_0000115 "The part of a synapse that is part of the presynaptic cell." ; oboInOwl:hasExactSynonym "presynaptic terminal" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098793" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynapse" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000540 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045202 ] . obo:GO_0098794 obo:IAO_0000115 "The part of a synapse that is part of the post-synaptic cell." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098794" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "postsynapse" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000000 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045202 ] . obo:GO_0098796 obo:IAO_0000115 "Any protein complex that is part of a membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098796" ; oboInOwl:inSubset go:goslim_metagenomics ; a owl:Class ; rdfs:label "membrane protein complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0098797 obo:IAO_0000115 "Any protein complex that is part of the plasma membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098797" ; a owl:Class ; rdfs:label "plasma membrane protein complex" ; rdfs:subClassOf obo:GO_0098796, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0098798 obo:IAO_0000115 "A protein complex that is part of a mitochondrion." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "mitochondrial protein complex" ; oboInOwl:id "GO:0098798" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "mitochondrial protein-containing complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0098801 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098801" ; a owl:Class ; rdfs:label "regulation of renal system process" ; rdfs:subClassOf obo:GO_0044057, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003014 ] ) ] . obo:GO_0098813 obo:IAO_0000115 "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098813" ; a owl:Class ; rdfs:label "nuclear chromosome segregation" ; rdfs:subClassOf obo:GO_0007059 . obo:GO_0098840 obo:IAO_0000115 "The directed movement of a protein along a microtubule, mediated by motor proteins." ; oboInOwl:hasBroadSynonym "microtubule-based protein transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098840" ; a owl:Class ; rdfs:label "protein transport along microtubule" ; rdfs:subClassOf obo:GO_0006886, obo:GO_0010970, obo:GO_0099118 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0098852 obo:IAO_0000115 "The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098852" ; a owl:Class ; rdfs:label "lytic vacuole membrane" ; rdfs:subClassOf obo:GO_0005774, [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0000323 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0000323 ] ) ] . obo:GO_0098858 obo:IAO_0000115 "A cell projection supported by an assembly of actin filaments, and which lacks microtubules." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098858" ; a owl:Class ; rdfs:label "actin-based cell projection" ; rdfs:subClassOf obo:GO_0120025, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005884 ] . obo:GO_0098867 obo:IAO_0000115 "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098867" ; a owl:Class ; rdfs:label "intramembranous bone growth" ; rdfs:subClassOf obo:GO_0098868, [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0002514 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0002514 ] ) ] . obo:GO_0098868 obo:IAO_0000115 "The increase in size or mass of a bone that contributes to the shaping of that bone." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098868" ; a owl:Class ; rdfs:label "bone growth" ; rdfs:subClassOf obo:GO_0035265, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060348 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0001474 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:RO_0002343 ; owl:someValuesFrom obo:UBERON_0001474 ] ) ] . obo:GO_0098871 obo:IAO_0000115 "The actin cytoskeleton that is part of a postsynapse." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098871" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "postsynaptic actin cytoskeleton" ; rdfs:subClassOf obo:GO_0015629, obo:GO_0099571 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0015629 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098794 ] ) ] . obo:GO_0098876 obo:IAO_0000115 "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098876" ; a owl:Class ; rdfs:label "vesicle-mediated transport to the plasma membrane" ; rdfs:subClassOf obo:GO_0016192, obo:GO_0051668, [ a owl:Restriction ; owl:onProperty obo:RO_0002230 ; owl:someValuesFrom obo:GO_0006887 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0005886 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0098883 obo:IAO_0000115 "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared." ; oboInOwl:hasExactSynonym "synapse clearance", "synapse disassembly", "synapse elimination", "synapse removal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098883" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synapse pruning" ; rdfs:subClassOf obo:GO_0050808, obo:GO_0150146, [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022411 [ a owl:Restriction ; owl:onProperty obo:RO_0002590 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0098900 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098900" ; a owl:Class ; rdfs:comment "The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term." ; rdfs:label "regulation of action potential" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001508 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050789 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001508 ] ) ] . obo:GO_0098901 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098901" ; a owl:Class ; rdfs:label "regulation of cardiac muscle cell action potential" ; rdfs:subClassOf obo:GO_0098900, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0086001 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050789 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0086001 ] ) ] . obo:GO_0098904 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-10T08:58:56Z" ; oboInOwl:hasExactSynonym "regulation of AV node cardiac muscle cell action potential", "regulation of atrioventricular node cardiac muscle cell action potential" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098904" ; a owl:Class ; rdfs:label "regulation of AV node cell action potential" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0098901, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0086016 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050789 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0086016 ] ) ] . obo:GO_0098906 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-10T08:58:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098906" ; a owl:Class ; rdfs:label "regulation of Purkinje myocyte action potential" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0098901, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0086017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050789 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0086017 ] ) ] . obo:GO_0098907 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2011-11-10T08:50:15Z" ; oboInOwl:hasExactSynonym "regulation of SA node cardiac muscle cell action potential", "regulation of SAN cardiac muscle cell action potential", "regulation of sinoatrial node cardiac muscle cell action potential" ; oboInOwl:hasNarrowSynonym "regulation of sinus node cardiac muscle cell action potential" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098907" ; a owl:Class ; rdfs:label "regulation of SA node cell action potential" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0098901, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0086015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050789 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0086015 ] ) ] . obo:GO_0098908 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "generation of action potential" ; oboInOwl:id "GO:0098908" ; a owl:Class ; rdfs:label "regulation of neuronal action potential" ; rdfs:subClassOf obo:GO_0051969, obo:GO_0098900, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019228 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050789 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019228 ] ) ] . obo:GO_0098916 obo:IAO_0000115 "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098916" ; a owl:Class ; rdfs:label "anterograde trans-synaptic signaling" ; rdfs:subClassOf obo:GO_0099537, [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098793 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002232 ; owl:someValuesFrom obo:GO_0098794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002232 ; owl:someValuesFrom obo:GO_0098794 ] ) ] . obo:GO_0098917 obo:IAO_0000115 "Cell-cell signaling from post to pre-synapse, across the synaptic cleft." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098917" ; a owl:Class ; rdfs:label "retrograde trans-synaptic signaling" ; rdfs:subClassOf obo:GO_0099537, [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098794 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002232 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002232 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0098920 obo:IAO_0000115 "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098920" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "retrograde trans-synaptic signaling by lipid" ; rdfs:subClassOf obo:GO_0098917, obo:GO_0099541 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002232 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0098926 obo:IAO_0000115 "Signal transduction in which the initial step occurs in a postsynapse." ; oboInOwl:hasExactSynonym "postsynaptic signaling pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098926" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "postsynaptic signal transduction" ; rdfs:subClassOf obo:GO_0007165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099536 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007165 [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098794 ] ) ] . obo:GO_0098928 obo:IAO_0000115 "Signal transduction in which the initial step occurs in a presynapse." ; oboInOwl:hasExactSynonym "presynaptic signaling pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098928" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic signal transduction" ; rdfs:subClassOf obo:GO_0007165, [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007165 [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0098930 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules in axons." ; oboInOwl:hasDbXref "Wikipedia:Axoplasmic_transport" ; oboInOwl:hasExactSynonym "axon cargo transport", "axoplasmic transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098930" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "axonal transport" ; rdfs:subClassOf obo:GO_0008088, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0030424 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0030424 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0098934 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098934" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "retrograde dendritic transport" ; rdfs:subClassOf obo:GO_0098935, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0032839 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0032839 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0098935 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules in dendrites." ; oboInOwl:hasExactSynonym "dendrite cargo transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098935" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "dendritic transport" ; rdfs:subClassOf obo:GO_0008088, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0030425 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0030425 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0098937 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098937" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "anterograde dendritic transport" ; rdfs:subClassOf obo:GO_0098935, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0032839 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0098794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0032839 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0098794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0098961 obo:IAO_0000115 "The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites." ; oboInOwl:hasExactSynonym "dendritic transport of RNP complex" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098961" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "dendritic transport of ribonucleoprotein complex" ; rdfs:subClassOf obo:GO_0031503, obo:GO_0098935, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0032839 ], [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_1990904 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0032839 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_1990904 ] ) ] . obo:GO_0098974 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098974" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "postsynaptic actin cytoskeleton organization" ; rdfs:subClassOf obo:GO_0030036, obo:GO_0099188, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0098871 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0098871 ] ) ] . obo:GO_0098975 obo:IAO_0000115 "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098975" ; a owl:Class ; rdfs:label "postsynapse of neuromuscular junction" ; rdfs:subClassOf obo:GO_0098794, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000187 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031594 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098794 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:CL_0000187 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031594 ] ) ] . obo:GO_0098981 obo:IAO_0000115 "A synapse that uses acetylcholine as a neurotransmitter." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098981" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "cholinergic synapse" ; rdfs:subClassOf obo:GO_0045202, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045202 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0007271 ] ) ] . obo:GO_0098982 obo:IAO_0000115 "A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098982" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "GABA-ergic synapse" ; rdfs:subClassOf obo:GO_0045202, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0051932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045202 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0051932 ] ) ] . obo:GO_0099003 obo:IAO_0000115 "Any vesicle-mediated transport that occurs in a synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099003" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "vesicle-mediated transport in synapse" ; rdfs:subClassOf obo:GO_0016192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0099024 obo:IAO_0000115 "An infolding of the plasma membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099024" ; a owl:Class ; rdfs:label "plasma membrane invagination" ; rdfs:subClassOf obo:GO_0010324 . obo:GO_0099054 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a presynapse." ; oboInOwl:hasExactSynonym "presynapse biogenesis", "presynaptic terminal assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099054" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynapse assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0099172, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007416 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099068 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a postsynapse." ; oboInOwl:hasExactSynonym "postsynapse biogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099068" ; a owl:Class ; rdfs:label "postsynapse assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0099173, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007416 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0098794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0098794 ] ) ] . obo:GO_0099080 obo:IAO_0000115 "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099080" ; a owl:Class ; rdfs:label "supramolecular complex" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0099081 obo:IAO_0000115 "A polymeric supramolecular structure." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099081" ; a owl:Class ; rdfs:label "supramolecular polymer" ; rdfs:subClassOf obo:GO_0099080, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0015006 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099080 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0015006 ] ) ] . obo:GO_0099082 obo:IAO_0000115 "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099082" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "retrograde trans-synaptic signaling by neuropeptide" ; rdfs:subClassOf obo:GO_0098917, obo:GO_0099540 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002232 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0099083 obo:IAO_0000115 "Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099083" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0099082, obo:GO_0099551 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002231 ; owl:someValuesFrom obo:GO_0098794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002232 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0099098 obo:IAO_0000115 "The movement of a cellular component as a result of microtubule polymerization." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099098" ; a owl:Class ; rdfs:label "microtubule polymerization based movement" ; rdfs:subClassOf obo:GO_0007018, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0046785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007018 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0046785 ] ) ] . obo:GO_0099111 obo:IAO_0000115 "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099111" ; a owl:Class ; rdfs:label "microtubule-based transport" ; rdfs:subClassOf obo:GO_0006810, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0005874 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0005874 ] ) ] . obo:GO_0099112 obo:IAO_0000115 "The transport of a protein driven by polymerization of a microtubule to which it is attached." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099112" ; a owl:Class ; rdfs:label "microtubule polymerization based protein transport" ; rdfs:subClassOf obo:GO_0006886, obo:GO_0099118, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0046785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0046785 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36080 ] ) ] . obo:GO_0099118 obo:IAO_0000115 "A microtubule-based process that results in the transport of proteins." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099118" ; a owl:Class ; rdfs:label "microtubule-based protein transport" ; rdfs:subClassOf obo:GO_0007017, obo:GO_0015031, obo:GO_0099111 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0099123 obo:IAO_0000115 "The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron." ; oboInOwl:hasExactSynonym "STD DA release", "STD dopamine release", "somatodendritic dopamine release" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099123" ; a owl:Class ; rdfs:label "somato-dendritic dopamine secretion" ; rdfs:subClassOf obo:GO_0014046, obo:GO_0051649, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0036477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0014046 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0036477 ] ) ] . obo:GO_0099124 obo:IAO_0000115 "The regulated release of dopamine from an axon." ; oboInOwl:hasExactSynonym "axonal DA release", "axonal dopamine release" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099124" ; a owl:Class ; rdfs:label "axonal dopamine secretion" ; rdfs:subClassOf obo:GO_0014046, obo:GO_0051649, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0030424 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0014046 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0030424 ] ) ] . obo:GO_0099140 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-06-09T18:34:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099140" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic actin cytoskeleton organization" ; rdfs:subClassOf obo:GO_0030036, obo:GO_0099187, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0099143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0099143 ] ) ] . obo:GO_0099143 obo:IAO_0000115 "The actin cytoskeleton that is part of a presynapse." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-06-09T18:36:19Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099143" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic actin cytoskeleton" ; rdfs:subClassOf obo:GO_0015629, obo:GO_0099569 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0015629 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099156 obo:IAO_0000115 "Cell-cell signaling in which the ligand is carried between cells by an exosome." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-07-05T16:40:45Z" ; oboInOwl:hasExactSynonym "exosome mediated" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099156" ; a owl:Class ; rdfs:label "cell-cell signaling via exosome" ; rdfs:subClassOf obo:GO_0007267, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0070062 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0070062 ] ) ] . obo:GO_0099157 obo:IAO_0000115 "Transynaptic signaling in which the ligand is carried across the synapse by an exosome." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-07-05T16:49:44Z" ; oboInOwl:hasExactSynonym "exosome mediated transynaptic signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099157" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "trans-synaptic signalling via exosome" ; rdfs:subClassOf obo:GO_0099156, obo:GO_0099537 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_0070062 ] ) ] . obo:GO_0099170 obo:IAO_0000115 "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-09-11T17:09:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099170" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "postsynaptic modulation of chemical synaptic transmission" ; rdfs:subClassOf obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050804 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098794 ] ) ] . obo:GO_0099171 obo:IAO_0000115 "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-09-11T17:09:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099171" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic modulation of chemical synaptic transmission" ; rdfs:subClassOf obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050804 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099172 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse." ; oboInOwl:hasExactSynonym "presynapse development", "presynapse organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "presynapse morphogenesis", "presynapse organization and biogenesis" ; oboInOwl:id "GO:0099172" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynapse organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050808 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099173 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse." ; oboInOwl:hasExactSynonym "postsynapse development", "postsynapse organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "postsynapse morphogenesis", "postsynapse organization and biogenesis" ; oboInOwl:id "GO:0099173" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "postsynapse organization" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050808 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0098794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0098794 ] ) ] . obo:GO_0099174 obo:IAO_0000115 "Any process that modulates the physical form of a presynapse." ; oboInOwl:hasExactSynonym "regulation of presynapse organisation", "regulation of presynapse structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of presynapse organization and biogenesis" ; oboInOwl:id "GO:0099174" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of presynapse organization" ; rdfs:subClassOf obo:GO_0050807, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099172 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099172 ] ) ] . obo:GO_0099175 obo:IAO_0000115 "Any process that modulates the physical form of a postsynapse." ; oboInOwl:hasExactSynonym "regulation of postsynapse organisation", "regulation of postsynapse structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of postsynapse organization and biogenesis" ; oboInOwl:id "GO:0099175" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of postsynapse organization" ; rdfs:subClassOf obo:GO_0050807, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099173 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099173 ] ) ] . obo:GO_0099177 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099177" ; a owl:Class ; rdfs:label "regulation of trans-synaptic signaling" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0023051, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099537 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099537 ] ) ] . obo:GO_0099187 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-12-20T15:05:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099187" ; a owl:Class ; rdfs:label "presynaptic cytoskeleton organization" ; rdfs:subClassOf obo:GO_0007010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099172 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0099569 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0099569 ] ) ] . obo:GO_0099188 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-12-20T15:06:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099188" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "postsynaptic cytoskeleton organization" ; rdfs:subClassOf obo:GO_0007010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099173 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0099571 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0099571 ] ) ] . obo:GO_0099500 obo:IAO_0000115 "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099500" ; a owl:Class ; rdfs:label "vesicle fusion to plasma membrane" ; rdfs:subClassOf obo:GO_0006906, obo:GO_0140029, [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0098590 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006887 ] [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0012506 ] [ a owl:Restriction ; owl:onProperty obo:RO_0012008 ; owl:someValuesFrom obo:GO_0098590 ] ) ] . obo:GO_0099501 obo:IAO_0000115 "The lipid bilayer surrounding an exocytic vesicle." ; oboInOwl:hasBroadSynonym "secretory vesicle membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099501" ; a owl:Class ; rdfs:label "exocytic vesicle membrane" ; rdfs:subClassOf obo:GO_0030658, [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0070382 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:RO_0002007 ; owl:someValuesFrom obo:GO_0070382 ] ) ] . obo:GO_0099503 obo:IAO_0000115 "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099503" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "secretory vesicle" ; rdfs:subClassOf obo:GO_0031410, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0099500 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031982 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0099500 ] ) ] . obo:GO_0099504 obo:IAO_0000115 "A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099504" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle cycle" ; rdfs:subClassOf obo:GO_0051649, obo:GO_0099003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] . obo:GO_0099512 obo:IAO_0000115 "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." ; oboInOwl:hasAlternativeId "GO:0043205" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "fibril" ; oboInOwl:id "GO:0099512" ; a owl:Class ; rdfs:label "supramolecular fiber" ; rdfs:subClassOf obo:GO_0099081, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002309 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099080 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0002309 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0015006 ] ) ] . obo:GO_0099513 obo:IAO_0000115 "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099513" ; a owl:Class ; rdfs:label "polymeric cytoskeletal fiber" ; rdfs:subClassOf obo:GO_0099512, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005856 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099512 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005856 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0015006 ] ) ] . obo:GO_0099514 obo:IAO_0000115 "The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099514" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle cytoskeletal transport" ; rdfs:subClassOf obo:GO_0048489, obo:GO_0099518 . obo:GO_0099515 obo:IAO_0000115 "The transport of organelles or other particles from one location in the cell to another along actin filaments." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-27T10:56:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099515" ; a owl:Class ; rdfs:label "actin filament-based transport" ; rdfs:subClassOf obo:GO_0030705, [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005884 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005884 ] ) ] . obo:GO_0099517 obo:IAO_0000115 "The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099517" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle transport along microtubule" ; rdfs:subClassOf obo:GO_0047496, obo:GO_0099514 . obo:GO_0099518 obo:IAO_0000115 "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." ; oboInOwl:hasExactSynonym "cytoskeletal fiber-based vesicle localization", "vesicle cytoskeletal transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099518" ; a owl:Class ; rdfs:label "vesicle cytoskeletal trafficking" ; rdfs:subClassOf obo:GO_0030705, obo:GO_0051650 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0099513 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0099522 obo:IAO_0000115 "Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol." ; oboInOwl:hasExactSynonym "region of cytosol" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099522" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "cytosolic region" ; rdfs:subClassOf obo:GO_0005829, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005829 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005829 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005829 ] ) ] . obo:GO_0099523 obo:IAO_0000115 "The region of the cytosol consisting of all cytosol that is part of the presynapse." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099523" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic cytosol" ; rdfs:subClassOf obo:GO_0099522, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005829 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005829 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099531 obo:IAO_0000115 "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099531" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic process involved in chemical synaptic transmission" ; rdfs:subClassOf obo:GO_0050877, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007268 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050877 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007268 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099536 obo:IAO_0000115 "Cell-cell signaling to, from or within a synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099536" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic signaling" ; rdfs:subClassOf obo:GO_0007267, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0099537 obo:IAO_0000115 "Cell-cell signaling in either direction across the synaptic cleft." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099537" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "trans-synaptic signaling" ; rdfs:subClassOf obo:GO_0099536 . obo:GO_0099538 obo:IAO_0000115 "Cell-cell signaling to or from a synapse, mediated by a peptide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099538" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic signaling via neuropeptide" ; rdfs:subClassOf obo:GO_0099536, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_16670 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099536 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0099540 obo:IAO_0000115 "Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099540" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "trans-synaptic signaling by neuropeptide" ; rdfs:subClassOf obo:GO_0099537, obo:GO_0099538 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0099541 obo:IAO_0000115 "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099541" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "trans-synaptic signaling by lipid" ; rdfs:subClassOf obo:GO_0099537, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_18059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0099546 obo:IAO_0000115 "Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099546" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "protein catabolic process, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0140246, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009056 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:CHEBI_36080 ] ) ] . obo:GO_0099547 obo:IAO_0000115 "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099547" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of translation at synapse, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0050804, obo:GO_0140243, [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099550 obo:IAO_0000115 "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099550" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "trans-synaptic signaling, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0050804, obo:GO_0099537 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099551 obo:IAO_0000115 "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099551" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "trans-synaptic signaling by neuropeptide, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0099540, obo:GO_0099550 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_16670 ] ) ] . obo:GO_0099552 obo:IAO_0000115 "Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099552" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "trans-synaptic signaling by lipid, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0099541, obo:GO_0099550 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:CHEBI_18059 ] ) ] . obo:GO_0099568 obo:IAO_0000115 "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099568" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "cytoplasmic region" ; rdfs:subClassOf obo:GO_0005737, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0099569 obo:IAO_0000115 "The portion of the cytoskeleton contained within the presynapse." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099569" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic cytoskeleton" ; rdfs:subClassOf obo:GO_0005856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005856 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099571 obo:IAO_0000115 "The portion of the cytoskeleton contained within the postsynapse." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099571" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "postsynaptic cytoskeleton" ; rdfs:subClassOf obo:GO_0005856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098794 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005856 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098794 ] ) ] . obo:GO_0099574 obo:IAO_0000115 "Any process that modulates synaptic transmission by regulating protein degradation at the synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099574" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of protein catabolic process at synapse, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0050804, obo:GO_0140250, [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009056 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_36080 ] ) ] . obo:GO_0099575 obo:IAO_0000115 "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099575" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of protein catabolic process at presynapse, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0042176, obo:GO_0099171 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042176 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099576 obo:IAO_0000115 "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099576" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of protein catabolic process at postsynapse, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0042176, obo:GO_0099170 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042176 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099577 obo:IAO_0000115 "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099577" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of translation at presynapse, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0099171, obo:GO_0099547, obo:GO_0140244 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099578 obo:IAO_0000115 "Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099578" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of translation at postsynapse, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0099170, obo:GO_0099547, obo:GO_0140245 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099612 obo:IAO_0000115 "A process in which a protein is transported to or maintained in a location within an axon." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099612" ; a owl:Class ; rdfs:label "protein localization to axon" ; rdfs:subClassOf obo:GO_0008104, [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0030424 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0030424 ] ) ] . obo:GO_0099632 obo:IAO_0000115 "A process in which protein is transported from one region of the plasma membrane to another." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099632" ; a owl:Class ; rdfs:label "protein transport within plasma membrane" ; rdfs:subClassOf obo:GO_0032594, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005886 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0099636 obo:IAO_0000115 "The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains." ; oboInOwl:hasDbXref "Wikipedia:Cytoplasmic_streaming" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099636" ; a owl:Class ; rdfs:label "cytoplasmic streaming" ; rdfs:subClassOf obo:GO_0016482 . obo:GO_0099640 obo:IAO_0000115 "The directed movement of proteins along microtubules in neuron projections." ; oboInOwl:hasNarrowSynonym "axonal protein transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099640" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "axo-dendritic protein transport" ; rdfs:subClassOf obo:GO_0008088, obo:GO_0098840 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0046907 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043005 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0099641 obo:IAO_0000115 "The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons." ; oboInOwl:hasBroadSynonym "anterograde axon cargo transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099641" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "anterograde axonal protein transport" ; rdfs:subClassOf obo:GO_0008089, obo:GO_0099640, obo:GO_1905383 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_1904115 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002339 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0099642 obo:IAO_0000115 "The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons." ; oboInOwl:hasBroadSynonym "retrograde axon cargo transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099642" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "retrograde axonal protein transport" ; rdfs:subClassOf obo:GO_0008090, obo:GO_0099640 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_1904115 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002338 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002341 ; owl:someValuesFrom obo:GO_0005874 ] [ a owl:Restriction ; owl:onProperty obo:RO_0004009 ; owl:someValuesFrom obo:PR_000000001 ] ) ] . obo:GO_0099643 obo:IAO_0000115 "Any signal release from a synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099643" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "signal release from synapse" ; rdfs:subClassOf obo:GO_0023061, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099536 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_33208 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0023061 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0099738 obo:IAO_0000115 "The complete extent of cell cortex that underlies some some region of the plasma membrane." ; oboInOwl:hasExactSynonym "perimembrane region" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099738" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "cell cortex region" ; rdfs:subClassOf obo:GO_0005938, obo:GO_0099568, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005938 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005938 ] ) ] . obo:GO_0100001 obo:IAO_0000115 "Any action potential process that regulates skeletal muscle contraction." ; oboInOwl:created_by "cjm" ; oboInOwl:creation_date "2015-04-02T04:13:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0100001" ; a owl:Class ; rdfs:label "regulation of skeletal muscle contraction by action potential" ; rdfs:subClassOf obo:BFO_0000015, obo:GO_0001508, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003009 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0001508 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003009 ] ) ] . obo:GO_0101023 obo:IAO_0000115 "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0101023" ; a owl:Class ; rdfs:label "vascular endothelial cell proliferation" ; rdfs:subClassOf obo:GO_0001935, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000071 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000071 ] ) ] . obo:GO_0101024 obo:IAO_0000115 "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19949"^^xsd:anyURI ; oboInOwl:hasExactSynonym "nuclear membrane organization involved in mitotic nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0101024" ; a owl:Class ; rdfs:comment "This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown." ; rdfs:label "mitotic nuclear membrane organization" ; rdfs:subClassOf obo:GO_0071763, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_2759 ], [ a owl:Restriction ; owl:allValuesFrom obo:NCBITaxon_2759 ; owl:onProperty obo:RO_0002162 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071763 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0101025 obo:IAO_0000115 "The process in which a nuclear membrane is synthesized, aggregates, and bonds together." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0101025" ; a owl:Class ; rdfs:label "nuclear membrane biogenesis" ; rdfs:subClassOf obo:GO_0044091, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071763 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:GO_0031965 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044085 [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:GO_0031965 ] ) ] . obo:GO_0104004 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-02-17T16:02:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0104004" ; a owl:Class ; rdfs:label "cellular response to environmental stimulus" ; rdfs:subClassOf obo:GO_0051716 . obo:GO_0106027 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2017-06-23T18:30:18Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0106027" ; a owl:Class ; rdfs:label "neuron projection organization" ; rdfs:subClassOf obo:GO_0120036, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0043005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0043005 ] ) ] . obo:GO_0106030 obo:IAO_0000115 "The collection of neuronal projections into a bundle of rods, known as a fascicle." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2017-06-26T19:43:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0106030" ; a owl:Class ; rdfs:label "neuron projection fasciculation" ; rdfs:subClassOf obo:GO_0031175 . obo:GO_0106049 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2017-08-04T14:53:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0106049" ; a owl:Class ; rdfs:label "regulation of cellular response to osmotic stress" ; rdfs:subClassOf obo:GO_0047484, obo:GO_0080135, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071470 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071470 ] ) ] . obo:GO_0106214 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2019-06-27T15:12:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0106214" ; a owl:Class ; rdfs:label "regulation of vesicle fusion with Golgi apparatus" ; rdfs:subClassOf obo:GO_0031338, obo:GO_1903358, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048280 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048280 ] ) ] . obo:GO_0106215 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2019-06-27T15:17:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0106215" ; a owl:Class ; rdfs:label "negative regulation of vesicle fusion with Golgi apparatus" ; rdfs:subClassOf obo:GO_0031339, obo:GO_0106214, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048280 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048280 ] ) ] . obo:GO_0106216 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2019-06-27T15:20:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0106216" ; a owl:Class ; rdfs:label "positive regulation of vesicle fusion with Golgi apparatus" ; rdfs:subClassOf obo:GO_0031340, obo:GO_0106214, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048280 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048280 ] ) ] . obo:GO_0110011 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane." ; oboInOwl:created_by "kmv" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110011" ; a owl:Class ; rdfs:label "regulation of basement membrane organization" ; rdfs:subClassOf obo:GO_1903053, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071711 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071711 ] ) ] . obo:GO_0110020 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-06-20T19:28:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110020" ; a owl:Class ; rdfs:label "regulation of actomyosin structure organization" ; rdfs:subClassOf obo:GO_0032956, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031032 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031032 ] ) ] . obo:GO_0110021 obo:IAO_0000115 "The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-06-29T14:35:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110021" ; a owl:Class ; rdfs:label "cardiac muscle myoblast proliferation" ; rdfs:subClassOf obo:GO_0051450, [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000513 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:RO_0012003 ; owl:someValuesFrom obo:CL_0000513 ] ) ] . obo:GO_0110022 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-06-29T15:11:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110022" ; a owl:Class ; rdfs:label "regulation of cardiac muscle myoblast proliferation" ; rdfs:subClassOf obo:GO_2000291, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0110021 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0110021 ] ) ] . obo:GO_0110023 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-06-29T15:18:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110023" ; a owl:Class ; rdfs:label "negative regulation of cardiac muscle myoblast proliferation" ; rdfs:subClassOf obo:GO_0110022, obo:GO_2000818, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0110021 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0110021 ] ) ] . obo:GO_0110024 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-06-29T15:24:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110024" ; a owl:Class ; rdfs:label "positive regulation of cardiac muscle myoblast proliferation" ; rdfs:subClassOf obo:GO_0110022, obo:GO_2000288, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0110021 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0110021 ] ) ] . obo:GO_0110028 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic spindle organization." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-07-06T14:14:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110028" ; a owl:Class ; rdfs:label "positive regulation of mitotic spindle organization" ; rdfs:subClassOf obo:GO_0045931, obo:GO_0051495, obo:GO_0060236, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007052 ] ) ] . obo:GO_0110029 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-07-12T18:47:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110029" ; a owl:Class ; rdfs:label "negative regulation of meiosis I" ; rdfs:subClassOf obo:GO_0045835, obo:GO_0060631, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0110040 obo:IAO_0000115 "The process in which the anatomical structures of the pharynx are generated and organized." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-07-24T20:51:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110040" ; a owl:Class ; rdfs:label "pharynx morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0006562 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:UBERON_0006562 ] ) ] . obo:GO_0110041 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-07-24T21:00:20Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110041" ; a owl:Class ; rdfs:label "regulation of pharynx morphogenesis" ; rdfs:subClassOf obo:GO_0022603, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0110040 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0110040 ] ) ] . obo:GO_0110042 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-07-24T21:05:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110042" ; a owl:Class ; rdfs:label "negative regulation of pharynx morphogenesis" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0110041, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0110040 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0110040 ] ) ] . obo:GO_0110043 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-07-24T21:09:48Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110043" ; a owl:Class ; rdfs:label "positive regulation of pharynx morphogenesis" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0110041, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0110040 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0110040 ] ) ] . obo:GO_0110053 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of actin filament organization." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-09-20T19:52:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110053" ; a owl:Class ; rdfs:label "regulation of actin filament organization" ; rdfs:subClassOf obo:GO_0032956, obo:GO_1902903, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007015 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007015 ] ) ] . obo:GO_0110057 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-10-23T14:32:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110057" ; a owl:Class ; rdfs:label "regulation of blood vessel endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0045601, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060837 ] ) ] . obo:GO_0110058 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-10-23T14:38:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110058" ; a owl:Class ; rdfs:label "positive regulation of blood vessel endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0045603, obo:GO_0110057, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060837 ] ) ] . obo:GO_0110059 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-10-23T14:47:29Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110059" ; a owl:Class ; rdfs:label "negative regulation of blood vessel endothelial cell differentiation" ; rdfs:subClassOf obo:GO_0045602, obo:GO_0110057, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060837 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060837 ] ) ] . obo:GO_0110077 obo:IAO_0000115 "A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-01-29T14:46:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110077" ; a owl:Class ; rdfs:label "vesicle-mediated intercellular transport" ; rdfs:subClassOf obo:GO_0010496, obo:GO_0016192, [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_1903561 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0010496 [ a owl:Restriction ; owl:onProperty obo:RO_0002608 ; owl:someValuesFrom obo:GO_1903561 ] ) ] . obo:GO_0110079 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of placenta blood vessel development." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-02-01T14:49:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110079" ; a owl:Class ; rdfs:label "regulation of placenta blood vessel development" ; rdfs:subClassOf obo:GO_1901342, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060674 ] ) ] . obo:GO_0110080 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of placenta blood vessel development." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-02-01T14:55:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110080" ; a owl:Class ; rdfs:label "positive regulation of placenta blood vessel development" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0110079, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060674 ] ) ] . obo:GO_0110081 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-02-01T15:01:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110081" ; a owl:Class ; rdfs:label "negative regulation of placenta blood vessel development" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0110079, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060674 ] ) ] . obo:GO_0110110 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-07-05T14:10:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110110" ; a owl:Class ; rdfs:label "positive regulation of animal organ morphogenesis" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0051240, obo:GO_2000027, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009887 ] ) ] . obo:GO_0110111 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-07-05T14:25:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110111" ; a owl:Class ; rdfs:label "negative regulation of animal organ morphogenesis" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0051241, obo:GO_2000027, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009887 ] ) ] . obo:GO_0110112 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of lipid transporter activity." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-07-06T18:53:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110112" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "regulation of lipid transporter activity" ; rdfs:subClassOf obo:GO_0032368, obo:GO_0032409, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005319 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005319 ] ) ] . obo:GO_0110113 obo:IAO_0000115 "Any process that increases the frequency, rate, or extent of lipid transporter activity." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-07-06T19:14:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110113" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "positive regulation of lipid transporter activity" ; rdfs:subClassOf obo:GO_0032370, obo:GO_0032411, obo:GO_0110112, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005319 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005319 ] ) ] . obo:GO_0110114 obo:IAO_0000115 "Any process that decreases the frequency, rate, or extent of lipid transporter activity." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-07-06T19:21:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110114" ; oboInOwl:inSubset go:term_scheduled_for_obsoletion ; a owl:Class ; rdfs:label "negative regulation of lipid transporter activity" ; rdfs:subClassOf obo:GO_0032369, obo:GO_0032410, obo:GO_0110112, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005319 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005319 ] ) ] . obo:GO_0110116 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-07-16T18:08:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110116" ; a owl:Class ; rdfs:label "regulation of compound eye photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0046532, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001751 ] ) ] . obo:GO_0110117 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-07-16T18:13:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110117" ; a owl:Class ; rdfs:label "positive regulation of compound eye photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0046534, obo:GO_0110116, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001751 ] ) ] . obo:GO_0110118 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-07-16T18:15:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110118" ; a owl:Class ; rdfs:label "negative regulation of compound eye photoreceptor cell differentiation" ; rdfs:subClassOf obo:GO_0046533, obo:GO_0110116, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001751 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001751 ] ) ] . obo:GO_0110122 obo:IAO_0000115 "The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-08-22T20:58:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110122" ; a owl:Class ; rdfs:label "myotube cell migration" ; rdfs:subClassOf obo:GO_0014812, [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0002372 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:RO_0002565 ; owl:someValuesFrom obo:CL_0002372 ] ) ] . obo:GO_0110123 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of myotube cell migration." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-08-22T21:06:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110123" ; a owl:Class ; rdfs:label "regulation of myotube cell migration" ; rdfs:subClassOf obo:GO_0030334, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0110122 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0110122 ] ) ] . obo:GO_0110124 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-08-22T21:09:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110124" ; a owl:Class ; rdfs:label "positive regulation of myotube cell migration" ; rdfs:subClassOf obo:GO_0030335, obo:GO_0110123, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0110122 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0110122 ] ) ] . obo:GO_0110125 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2018-08-22T21:12:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110125" ; a owl:Class ; rdfs:label "negative regulation of myotube cell migration" ; rdfs:subClassOf obo:GO_0030336, obo:GO_0110123, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0110122 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0110122 ] ) ] . obo:GO_0110165 obo:IAO_0000115 "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2019-08-12T18:01:37Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0110165" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular anatomical entity" ; rdfs:subClassOf obo:CARO_0000000, obo:GO_0005575 . obo:GO_0110166 obo:IAO_0000115 "Any DNA biosynthetic process that is involved in mitochondrial DNA replication." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17716"^^xsd:anyURI ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2020-03-18T13:30:39Z" ; oboInOwl:hasExactSynonym "DNA biosynthetic process involved in mitochondrial DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110166" ; a owl:Class ; rdfs:label "DNA synthesis involved in mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0032042, obo:GO_0090592, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071897 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006264 ] ) ] . obo:GO_0120023 obo:IAO_0000115 "Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13143"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-03-17T14:54:21Z" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0120023" ; a owl:Class ; rdfs:label "somatostatin binding" ; rdfs:subClassOf obo:GO_0017046, [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_64628 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:RO_0002233 ; owl:someValuesFrom obo:CHEBI_64628 ] ) ] . obo:GO_0120025 obo:IAO_0000115 "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13193"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-03-21T17:26:07Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0120025" ; a owl:Class ; rdfs:label "plasma membrane bounded cell projection" ; rdfs:subClassOf obo:GO_0042995, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0098590 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042995 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0098590 ] ) ] . obo:GO_0120031 obo:IAO_0000115 "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-24T23:56:08Z" ; oboInOwl:hasNarrowSynonym "eupodium" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120031" ; a owl:Class ; rdfs:label "plasma membrane bounded cell projection assembly" ; rdfs:subClassOf obo:GO_0030031, obo:GO_0120036, [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0120025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:RO_0002588 ; owl:someValuesFrom obo:GO_0120025 ] ) ] . obo:GO_0120032 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-26T04:27:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120032" ; a owl:Class ; rdfs:label "regulation of plasma membrane bounded cell projection assembly" ; rdfs:subClassOf obo:GO_0060491, obo:GO_0120035, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0120031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0120031 ] ) ] . obo:GO_0120033 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-26T04:34:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120033" ; a owl:Class ; rdfs:label "negative regulation of plasma membrane bounded cell projection assembly" ; rdfs:subClassOf obo:GO_0031345, obo:GO_0120032, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0120031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0120031 ] ) ] . obo:GO_0120034 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-26T04:34:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120034" ; a owl:Class ; rdfs:label "positive regulation of plasma membrane bounded cell projection assembly" ; rdfs:subClassOf obo:GO_0031346, obo:GO_0044089, obo:GO_0120032, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0120031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0120031 ] ) ] . obo:GO_0120035 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-26T16:02:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120035" ; a owl:Class ; rdfs:label "regulation of plasma membrane bounded cell projection organization" ; rdfs:subClassOf obo:GO_0031344, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0120036 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0120036 ] ) ] . obo:GO_0120036 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-26T16:07:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120036" ; a owl:Class ; rdfs:label "plasma membrane bounded cell projection organization" ; rdfs:subClassOf obo:GO_0030030, [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0120025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016043 [ a owl:Restriction ; owl:onProperty obo:RO_0002592 ; owl:someValuesFrom obo:GO_0120025 ] ) ] . obo:GO_0120039 obo:IAO_0000115 "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-28T23:39:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120039" ; a owl:Class ; rdfs:label "plasma membrane bounded cell projection morphogenesis" ; rdfs:subClassOf obo:GO_0048858, [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0120025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009653 [ a owl:Restriction ; owl:onProperty obo:RO_0002298 ; owl:someValuesFrom obo:GO_0120025 ] ) ] . obo:GO_0120111 obo:IAO_0000115 "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-11-01T18:58:12Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0120111" ; a owl:Class ; rdfs:label "neuron projection cytoplasm" ; rdfs:subClassOf obo:GO_0032838, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043005 ] ) ] . obo:GO_0120158 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/15720"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2018-05-11T16:31:42Z" ; oboInOwl:hasExactSynonym "positive regulation of collagen breakdown", "positive regulation of collagen catabolism", "positive regulation of collagen degradation", "up regulation of collagen catabolic process", "up-regulation of collagen catabolic process", "upregulation of collagen catabolic process" ; oboInOwl:hasNarrowSynonym "activation of collagen catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120158" ; a owl:Class ; rdfs:label "positive regulation of collagen catabolic process" ; rdfs:subClassOf obo:GO_0009896, obo:GO_0010710, obo:GO_0010714, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030574 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030574 ] ) ] . obo:GO_0120178 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/16000"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2019-05-20T22:34:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120178" ; a owl:Class ; rdfs:label "steroid hormone biosynthetic process" ; rdfs:subClassOf obo:GO_0006694, [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:CHEBI_26764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006694 [ a owl:Restriction ; owl:onProperty obo:RO_0002234 ; owl:someValuesFrom obo:CHEBI_26764 ] ) ] . obo:GO_0120186 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/16012"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2018-07-14T00:19:32Z" ; oboInOwl:hasExactSynonym "negative regulation of protein localisation to chromatin" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120186" ; a owl:Class ; rdfs:label "negative regulation of protein localization to chromatin" ; rdfs:subClassOf obo:GO_1903828, obo:GO_1905634, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071168 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071168 ] ) ] . obo:GO_0120187 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/16012"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2018-07-14T00:21:28Z" ; oboInOwl:hasExactSynonym "positive regulation of protein localisation to chromatin" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120187" ; a owl:Class ; rdfs:label "positive regulation of protein localization to chromatin" ; rdfs:subClassOf obo:GO_1903829, obo:GO_1905634, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071168 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071168 ] ) ] . obo:GO_0120188 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/16040"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboIn