@prefix rdf: . @prefix : . @prefix cl: . @prefix dc: . @prefix go: . @prefix pr: . @prefix obo: . @prefix owl: . @prefix xml: . @prefix xsd: . @prefix caro: . @prefix cito: . @prefix core: . @prefix fbbt: . @prefix foaf: . @prefix obda: . @prefix obo1: . @prefix pato: . @prefix rdfs: . @prefix skos: . @prefix swrl: . @prefix chebi: . @prefix core1: . @prefix swrla: . @prefix swrlb: . @prefix terms: . @prefix chebi2: . @prefix chebi3: . @prefix chebi4: . @prefix chebi5: . @prefix terms2: . @prefix ubprop: . @prefix protege: . @prefix subsets: . @prefix taxslim: . @prefix oboInOwl: . @prefix ncbitaxon: . @prefix oboInOwl1: . @prefix wbphenotype: . @prefix caloha-reqs-vetted: . protege:defaultLanguage a owl:AnnotationProperty . obo:BFO_0000001 obo:BFO_0000179 "entity" ; obo:BFO_0000180 "Entity" ; obo:IAO_0000112 "Julius Caesar"@en, "Verdi’s Requiem"@en, "the Second World War"@en, "your body mass index"@en ; obo:IAO_0000116 "BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81"@en, "Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf"@en ; obo:IAO_0000600 "An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])"@en ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "entity"@en . obo:BFO_0000002 obo:BFO_0000179 "continuant" ; obo:BFO_0000180 "Continuant" ; obo:IAO_0000115 "An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts."@en ; obo:IAO_0000116 "BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240"@en, "Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants"@en ; obo:IAO_0000600 "A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])"@en ; obo:IAO_0000601 "if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])"@en, "if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])"@en, "if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])"@en ; obo:IAO_0000602 "(forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002] ", "(forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001] ", "(forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002] ", "(forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "continuant"@en ; rdfs:subClassOf obo:BFO_0000001, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000002 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith obo:BFO_0000003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:BFO_0000003 ] . obo:BFO_0000003 obo:BFO_0000179 "occurrent" ; obo:BFO_0000180 "Occurrent" ; obo:IAO_0000115 "An entity that has temporal parts and that happens, unfolds or develops through time."@en ; obo:IAO_0000116 "BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region"@en, "BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players."@en, "Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process."@en, "Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame." ; obo:IAO_0000600 "An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])"@en ; obo:IAO_0000601 "Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])"@en, "b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001] ", "(forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "occurrent"@en ; rdfs:subClassOf obo:BFO_0000001, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000003 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:BFO_0000002 ] . obo:BFO_0000004 obo:BFO_0000179 "ic" ; obo:BFO_0000180 "IndependentContinuant" ; obo:IAO_0000112 "a chair"@en, "a heart"@en, "a leg"@en, "a molecule"@en, "a spatial region"@en, "an atom"@en, "an orchestra."@en, "an organism"@en, "the bottom right portion of a human torso"@en, "the interior of your mouth"@en ; obo:IAO_0000115 "b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])"@en ; obo:IAO_0000601 "For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])"@en, "For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])"@en ; obo:IAO_0000602 "(forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001] ", "(forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002] ", "(iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002] " ; a owl:Class ; rdfs:comment "A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything."@en ; rdfs:isDefinedBy ; rdfs:label "independent continuant"@en ; rdfs:subClassOf obo:BFO_0000002, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000004 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith obo:BFO_0000020, obo:BFO_0000031 . obo:BFO_0000015 obo:IAO_0000115 "p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])"@en ; a owl:Class ; rdfs:comment "An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t."@en ; rdfs:label "process"@en ; rdfs:subClassOf obo:BFO_0000003 . obo:BFO_0000016 obo:BFO_0000179 "disposition" ; obo:BFO_0000180 "Disposition" ; obo:IAO_0000112 "an atom of element X has the disposition to decay to an atom of element Y"@en, "certain people have a predisposition to colon cancer"@en, "children are innately disposed to categorize objects in certain ways."@en, "the cell wall is disposed to filter chemicals in endocytosis and exocytosis"@en ; obo:IAO_0000116 "BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type."@en ; obo:IAO_0000600 "b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])"@en ; obo:IAO_0000601 "If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])"@en ; obo:IAO_0000602 "(forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002] ", "(forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "disposition"@en ; rdfs:subClassOf obo:BFO_0000017 ; owl:disjointWith obo:BFO_0000023 . obo:BFO_0000017 obo:BFO_0000179 "realizable" ; obo:BFO_0000180 "RealizableEntity" ; obo:IAO_0000112 "the disposition of this piece of metal to conduct electricity."@en, "the disposition of your blood to coagulate"@en, "the function of your reproductive organs"@en, "the role of being a doctor"@en, "the role of this boundary to delineate where Utah and Colorado meet"@en ; obo:IAO_0000115 "A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances."@en ; obo:IAO_0000600 "To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])"@en ; obo:IAO_0000601 "All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])"@en ; obo:IAO_0000602 "(forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002] ", "(forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "realizable entity"@en ; rdfs:subClassOf obo:BFO_0000020, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000017 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith obo:BFO_0000019 . obo:BFO_0000019 obo:BFO_0000179 "quality" ; obo:BFO_0000180 "Quality" ; obo:IAO_0000112 "the ambient temperature of this portion of air"@en, "the color of a tomato"@en, "the length of the circumference of your waist"@en, "the mass of this piece of gold."@en, "the shape of your nose"@en, "the shape of your nostril"@en ; obo:IAO_0000600 "a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])"@en ; obo:IAO_0000601 "If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001] ", "(forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "quality"@en ; rdfs:subClassOf obo:BFO_0000020, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000019 ; owl:onProperty obo:BFO_0000050 ] . obo:BFO_0000020 obo:BFO_0000179 "sdc" ; obo:BFO_0000180 "SpecificallyDependentContinuant" ; obo:IAO_0000112 "Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key"@en, "of one-sided specifically dependent continuants: the mass of this tomato"@en, "of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates."@en, "the disposition of this fish to decay"@en, "the function of this heart: to pump blood"@en, "the mutual dependence of proton donors and acceptors in chemical reactions [79"@en, "the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction"@en, "the pink color of a medium rare piece of grilled filet mignon at its center"@en, "the role of being a doctor"@en, "the shape of this hole."@en, "the smell of this portion of mozzarella"@en ; obo:IAO_0000115 "b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])"@en ; obo:IAO_0000116 "Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc."@en ; obo:IAO_0000602 "(iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003] " ; a owl:Class ; rdfs:comment "A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same."@en ; rdfs:isDefinedBy ; rdfs:label "specifically dependent continuant"@en ; rdfs:subClassOf obo:BFO_0000002, [ a owl:Restriction ; owl:allValuesFrom obo:BFO_0000020 ; owl:onProperty obo:BFO_0000050 ] ; owl:disjointWith obo:BFO_0000031 . obo:BFO_0000023 obo:BFO_0000179 "role" ; obo:BFO_0000180 "Role" ; obo:IAO_0000112 "John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married."@en, "the priest role"@en, "the role of a boundary to demarcate two neighboring administrative territories"@en, "the role of a building in serving as a military target"@en, "the role of a stone in marking a property boundary"@en, "the role of subject in a clinical trial"@en, "the student role"@en ; obo:IAO_0000115 "A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts."@en ; obo:IAO_0000116 "BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives."@en ; obo:IAO_0000600 "b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "role"@en ; rdfs:subClassOf obo:BFO_0000017 . obo:BFO_0000031 obo:BFO_0000179 "gdc" ; obo:BFO_0000180 "GenericallyDependentContinuant" ; obo:IAO_0000112 "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity."@en, "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop"@en, "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule."@en ; obo:IAO_0000115 "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en ; obo:IAO_0000602 "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "generically dependent continuant"@en ; rdfs:subClassOf obo:BFO_0000002 . obo:BFO_0000034 obo:BFO_0000179 "function" ; obo:BFO_0000180 "Function" ; obo:IAO_0000112 "the function of a hammer to drive in nails"@en, "the function of a heart pacemaker to regulate the beating of a heart through electricity"@en, "the function of amylase in saliva to break down starch into sugar"@en ; obo:IAO_0000116 "BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc."@en ; obo:IAO_0000600 "A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])"@en ; obo:IAO_0000602 "(forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001] " ; a owl:Class ; rdfs:isDefinedBy ; rdfs:label "function"@en ; rdfs:subClassOf obo:BFO_0000016 . obo:BFO_0000040 obo:IAO_0000115 "An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time."@en ; a owl:Class ; rdfs:label "material entity"@en ; rdfs:subClassOf obo:BFO_0000004 . obo:BFO_0000050 obo:IAO_0000111 "is part of"@en ; obo:IAO_0000112 "my brain is part of my body (continuant parthood, two material entities)"@en, "my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)"@en, "this day is part of this year (occurrent parthood)"@en ; obo:IAO_0000115 "a core relation that holds between a part and its whole"@en ; obo:IAO_0000116 "Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other."@en, "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en, """Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'."""@en ; obo:IAO_0000118 "part_of"@en ; obo:RO_0001900 obo:RO_0001901 ; obo:RO_0040042 obo:BFO_0000002, obo:BFO_0000003, obo:BFO_0000004, obo:BFO_0000017, obo:BFO_0000019, obo:BFO_0000020, obo:BFO_0000031 ; oboInOwl:hasDbXref "BFO:0000050" ; oboInOwl:hasOBONamespace "external", "quality", "worm_anatomy", "worm_development" ; oboInOwl:id "part_of" ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_gp2term, obo:valid_for_go_ontology, obo:valid_for_gocam ; oboInOwl:shorthand "part_of" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "part of", "part of"@en, "part_of" ; rdfs:seeAlso , , "http://www.obofoundry.org/ro/#OBO_REL:part_of", "https://wiki.geneontology.org/Part_of"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002131 ; owl:inverseOf obo:BFO_0000051 . obo:BFO_0000051 obo:IAO_0000111 "has part"@en ; obo:IAO_0000112 "my body has part my brain (continuant parthood, two material entities)"@en, "my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)"@en, "this year has part this day (occurrent parthood)"@en ; obo:IAO_0000115 "a core relation that holds between a whole and its part"@en ; obo:IAO_0000116 "Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part."@en, "Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/"@en, """Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'."""@en ; obo:IAO_0000118 "has_part"@en ; obo:RO_0001900 obo:RO_0001901 ; oboInOwl:hasDbXref "BFO:0000051" ; oboInOwl:hasOBONamespace "chebi_ontology", "external", "quality" ; oboInOwl:id "has_part" ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; oboInOwl:is_cyclic false ; oboInOwl:shorthand "has_part" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "has part", "has part"@en, "has_part" ; rdfs:subPropertyOf obo:RO_0002131 . obo:BFO_0000062 obo:IAO_0000111 "preceded by"@en ; obo:IAO_0000115 "x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ; obo:IAO_0000116 "An example is: translation preceded_by transcription; aging preceded_by development (not however death preceded_by aging). Where derives_from links classes of continuants, preceded_by links classes of processes. Clearly, however, these two relations are not independent of each other. Thus if cells of type C1 derive_from cells of type C, then any cell division involving an instance of C1 in a given lineage is preceded_by cellular processes involving an instance of C. The assertion P preceded_by P1 tells us something about Ps in general: that is, it tells us something about what happened earlier, given what we know about what happened later. Thus it does not provide information pointing in the opposite direction, concerning instances of P1 in general; that is, that each is such as to be succeeded by some instance of P. Note that an assertion to the effect that P preceded_by P1 is rather weak; it tells us little about the relations between the underlying instances in virtue of which the preceded_by relation obtains. Typically we will be interested in stronger relations, for example in the relation immediately_preceded_by, or in relations which combine preceded_by with a condition to the effect that the corresponding instances of P and P1 share participants, or that their participants are connected by relations of derivation, or (as a first step along the road to a treatment of causality) that the one process in some way affects (for example, initiates or regulates) the other."@en ; obo:IAO_0000118 "is preceded by"@en, "preceded_by"@en ; terms:source "http://www.obofoundry.org/ro/#OBO_REL:preceded_by" ; oboInOwl:hasDbXref "BFO:0000062" ; oboInOwl:hasOBONamespace "worm_development" ; oboInOwl:id "preceded_by" ; oboInOwl:inSubset subsets:ro-eco ; oboInOwl:shorthand "preceded_by" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "preceded by"@en, "preceded_by" ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:RO_0002086 ; owl:inverseOf obo:BFO_0000063 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000062 ) . obo:BFO_0000063 obo:IAO_0000111 "precedes"@en ; obo:IAO_0000115 "x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point."@en ; oboInOwl:inSubset subsets:ro-eco ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "precedes"@en ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:RO_0002222 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000063 ) . obo:BFO_0000066 obo:IAO_0000111 "occurs in"@en ; obo:IAO_0000115 "b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ; obo:IAO_0000118 "occurs_in"@en, "unfolds in"@en, "unfolds_in"@en ; oboInOwl:hasDbXref "BFO:0000066" ; oboInOwl:hasOBONamespace "external" ; oboInOwl:id "occurs_in" ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; oboInOwl:shorthand "occurs_in" ; a owl:ObjectProperty ; rdfs:comment "Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant" ; rdfs:domain obo:BFO_0000003 ; rdfs:isDefinedBy ; rdfs:label "occurs in", "occurs in"@en ; rdfs:range obo:BFO_0000004 ; rdfs:seeAlso "https://wiki.geneontology.org/Occurs_in"^^xsd:anyURI ; owl:inverseOf obo:BFO_0000067 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000066 ), (obo:BFO_0000066 obo:BFO_0000050 ) . obo:BFO_0000067 obo:IAO_0000111 "site of"@en ; obo:IAO_0000115 "[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t"@en ; a owl:ObjectProperty ; rdfs:comment "Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant" ; rdfs:isDefinedBy ; rdfs:label "contains process"@en . obo:BFO_0000070 a owl:ObjectProperty . obo:BFO_0000179 a owl:AnnotationProperty . obo:BFO_0000180 a owl:AnnotationProperty . obo:CARO_0010004 a owl:Class . obo:CHEBI_10545 obo:IAO_0000115 "Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV." ; chebi:charge "-1" ; chebi:mass "0.000548579903" ; chebi:monoisotopicmass "0.0" ; oboInOwl:hasDbXref "KEGG:C05359", "PMID:21614077", "Wikipedia:Electron" ; oboInOwl:hasExactSynonym "electron" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Elektron", "beta", "beta(-)", "beta-particle", "e", "e(-)", "e-", "negatron" ; oboInOwl:id "CHEBI:10545" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "electron" ; rdfs:subClassOf obo:CHEBI_36338 . obo:CHEBI_131604 obo:IAO_0000115 "Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Mycoplasma genitalium metabolites" ; oboInOwl:id "CHEBI:131604" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "Mycoplasma genitalium metabolite" ; rdfs:subClassOf obo:CHEBI_76969 . obo:CHEBI_132717 obo:IAO_0000115 "A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties." ; oboInOwl:hasDbXref "Wikipedia:Bleach" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:132717" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bleaching agent" ; rdfs:subClassOf obo:CHEBI_33893 . obo:CHEBI_132992 obo:IAO_0000115 "A drug that makes increases the sensitivity of tumour cells to radiation therapy." ; oboInOwl:hasDbXref "PMID:12520460", "Wikipedia:Radiosensitizer" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "radiosensitiser", "radiosensitisers", "radiosensitising agent", "radiosensitising agents", "radiosensitizer", "radiosensitizers", "radiosensitizing agents" ; oboInOwl:id "CHEBI:132992" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "radiosensitizing agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_134179 obo:IAO_0000115 "Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa." ; oboInOwl:hasDbXref "Wikipedia:Volatile_organic_compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "VOC", "VOCs", "volatile organic compounds" ; oboInOwl:id "CHEBI:134179" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "volatile organic compound" ; rdfs:subClassOf obo:CHEBI_72695 . obo:CHEBI_134249 obo:IAO_0000115 "An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups." ; chebi:charge "-1" ; chebi:formula "CH2O3SR" ; chebi:mass "94.091" ; chebi:monoisotopicmass "93.97246" ; chebi:smiles "C(S([O-])(=O)=O)*" ; oboInOwl:hasAlternativeId "CHEBI:22318" ; oboInOwl:hasDbXref "MetaCyc:Alkanesulfonates" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkanesulfonate oxoanions", "alkanesulfonates", "an alkanesulfonate" ; oboInOwl:id "CHEBI:134249" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkanesulfonate oxoanion" ; rdfs:subClassOf obo:CHEBI_33554 . obo:CHEBI_136859 obo:IAO_0000115 "A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent." ; oboInOwl:hasDbXref "PMID:26449612" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pro-agents", "proagent", "proagents" ; oboInOwl:id "CHEBI:136859" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pro-agent" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_136889 obo:IAO_0000115 "Any steroid that has beta-configuration at position 5." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5beta steroids", "5beta-steroid", "5beta-steroids" ; oboInOwl:id "CHEBI:136889" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "5beta steroid" ; rdfs:subClassOf obo:CHEBI_35341 . obo:CHEBI_137041 obo:IAO_0000115 "The monoprotonated form of quinine, the predominant species at pH7.3." ; chebi:charge "+1" ; chebi:formula "C20H25N2O2" ; chebi:inchi "InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/p+1/t13-,14-,19-,20+/m0/s1" ; chebi:inchikey "LOUPRKONTZGTKE-WZBLMQSHSA-O" ; chebi:mass "325.42470" ; chebi:monoisotopicmass "325.19105" ; chebi:smiles "[H][C@]1(C[C@@H]2CC[N@H+]1C[C@@H]2C=C)[C@H](O)c1ccnc2ccc(OC)cc12" ; oboInOwl:hasExactSynonym "(9R)-9-hydroxy-6'-methoxy-8alpha-cinchonan-1-ium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "quinine" ; oboInOwl:id "CHEBI:137041" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "quinine(1+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_51323, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_51371 ], [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_59138 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15854 ] . obo:CHEBI_137980 obo:IAO_0000115 "An atom of an element that exhibits properties that are between those of metals and nonmetals, or that has a mixture of them. The term generally includes boron, silicon, germanium, arsenic, antimony, and tellurium, while carbon, aluminium, selenium, polonium, and astatine are less commonly included." ; oboInOwl:hasDbXref "Wikipedia:Metalloid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metalloid", "metalloids" ; oboInOwl:id "CHEBI:137980" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "metalloid atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_137982 obo:IAO_0000115 "An organic cation obtained by protonation of the amino group of any tertiary amino compound." ; chebi:charge "+1" ; chebi:formula "HNR3" ; chebi:mass "15.015" ; chebi:monoisotopicmass "15.01090" ; chebi:smiles "[NH+](*)(*)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a tertiary amine", "tertiary amine(1+)", "tertiary ammonium ions" ; oboInOwl:id "CHEBI:137982" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tertiary ammonium ion" ; rdfs:subClassOf obo:CHEBI_25697, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_50996 ] . obo:CHEBI_138000 obo:IAO_0000115 "An N-alkylpyrrolidine that consists of N-methylpyrrolidine bearing a pyridin-3-yl substituent at position 2." ; chebi:charge "0" ; chebi:formula "C10H14N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3" ; chebi:inchikey "SNICXCGAKADSCV-UHFFFAOYSA-N" ; chebi:mass "162.232" ; chebi:monoisotopicmass "162.11570" ; chebi:smiles "C=1C=C(C2N(CCC2)C)C=NC1" ; oboInOwl:hasExactSynonym "3-(1-methylpyrrolidin-2-yl)pyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:138000" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "3-(1-methylpyrrolidin-2-yl)pyridine" ; rdfs:subClassOf obo:CHEBI_26416, obo:CHEBI_26456, obo:CHEBI_46775 . obo:CHEBI_138015 obo:IAO_0000115 "Any compound that can disrupt the functions of the endocrine (hormone) system" ; oboInOwl:hasDbXref "PMID:27929035", "PMID:28356401", "PMID:28526231", "Wikipedia:Endocrine_disruptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "endocrine disrupting chemical", "endocrine disrupting chemicals", "endocrine disrupting compound", "endocrine disrupting compounds", "endocrine disruptors", "endocrine-disrupting chemical", "endocrine-disrupting chemicals", "hormonally active agent", "hormonally active agents" ; oboInOwl:id "CHEBI:138015" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "endocrine disruptor" ; rdfs:subClassOf obo:CHEBI_51061 . obo:CHEBI_138103 obo:IAO_0000115 "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water." ; oboInOwl:hasDbXref "Wikipedia:Mineral_acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic acids", "mineral acid", "mineral acids" ; oboInOwl:id "CHEBI:138103" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic acid" ; rdfs:subClassOf obo:CHEBI_39141 . obo:CHEBI_138675 obo:IAO_0000115 "Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa)." ; oboInOwl:hasDbXref "Wikipedia:https://en.wikipedia.org/wiki/Gas" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gas molecular entities", "gaseous molecular entities", "gaseous molecular entity" ; oboInOwl:id "CHEBI:138675" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "gas molecular entity" ; rdfs:subClassOf obo:CHEBI_33579 . obo:CHEBI_13941 chebi:charge "-1" ; chebi:formula "CH2NO2" ; chebi:inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)/p-1" ; chebi:inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-M" ; chebi:mass "60.03212" ; chebi:monoisotopicmass "60.00910" ; chebi:smiles "NC([O-])=O" ; oboInOwl:hasDbXref "Beilstein:3903503", "CAS:302-11-4", "Gmelin:239604" ; oboInOwl:hasExactSynonym "carbamate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Carbamat", "Karbamat", "carbamate ion", "carbamic acid, ion(1-)" ; oboInOwl:id "CHEBI:13941" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbamate" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_28616 ] . obo:CHEBI_139588 obo:IAO_0000115 "An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety." ; oboInOwl:hasDbXref "PMID:15326516", "PMID:19908854", "PMID:20382022", "PMID:23295224" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-hydroxy ketones", "alpha-hydroxy-ketone", "alpha-hydroxy-ketones", "alpha-hydroxyketone", "alpha-hydroxyketones" ; oboInOwl:id "CHEBI:139588" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-hydroxy ketone" ; rdfs:subClassOf obo:CHEBI_30879, obo:CHEBI_52396 . obo:CHEBI_139592 obo:IAO_0000115 "An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups." ; chebi:charge "0" ; chebi:formula "C2HO2R3" ; chebi:mass "57.028" ; chebi:monoisotopicmass "56.99765" ; chebi:smiles "C(C(=O)*)(O)(*)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tertiary alpha-hydroxy ketones", "tertiary alpha-hydroxy-ketone", "tertiary alpha-hydroxy-ketones", "tertiary alpha-hydroxyketone", "tertiary alpha-hydroxyketones" ; oboInOwl:id "CHEBI:139592" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tertiary alpha-hydroxy ketone" ; rdfs:subClassOf obo:CHEBI_139588, obo:CHEBI_26878 . obo:CHEBI_140601 obo:IAO_0000115 "Any saturated fatty acid containing 4 carbons." ; chebi:charge "0" ; chebi:formula "CHO2R" ; chebi:mass "45.017" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "*C(O)=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:140601" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fatty acid 4:0" ; rdfs:subClassOf obo:CHEBI_26666, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_78115 ] . obo:CHEBI_142355 obo:IAO_0000115 "A purine ribonucleoside that is a purine derivative attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage." ; chebi:charge "0" ; chebi:formula "C10H11N4O4R2" ; chebi:mass "251.219" ; chebi:monoisotopicmass "251.07803" ; chebi:smiles "C1(=*)NC(=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a purine D-ribonucleoside" ; oboInOwl:id "CHEBI:142355" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purines D-ribonucleoside" ; rdfs:subClassOf obo:CHEBI_26399, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_26386 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_47013 ] . obo:CHEBI_142513 obo:IAO_0000115 "A organic ion resulting from the deprotonation of the hydroxy group of any oxime." ; chebi:charge "-1" ; chebi:formula "CNO" ; chebi:mass "42.017" ; chebi:monoisotopicmass "41.99799" ; chebi:smiles "C(*)(=N[O-])*" ; oboInOwl:hasExactSynonym "oxime anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oximate", "oximates", "oxime anions" ; oboInOwl:id "CHEBI:142513" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxime anion" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_25750 ] . obo:CHEBI_145798 obo:IAO_0000115 "An organic anion that is the conjugate base of ouabain resulting from the deprotonation of the furanone moiety; major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C29H43O12" ; chebi:inchi "InChI=1S/C29H43O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,11,13,15-19,21-25,30-32,34-38H,3-6,8-10,12H2,1-2H3/q-1/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1" ; chebi:inchikey "MPLJNVZJPLASQC-HBYQJFLCSA-N" ; chebi:mass "583.652" ; chebi:monoisotopicmass "583.27600" ; chebi:smiles "O1[C@H]([C@@H]([C@H]([C@H]([C@@H]1O[C@H]2C[C@H]([C@]3([C@@](C2)(CC[C@]4([C@]5(CC[C@@H]([C@]5(C[C@H]([C@]34[H])O)C)C=6[CH-]OC(C6)=O)O)[H])O)CO)O)O)O)O)C" ; oboInOwl:hasDbXref "PMID:31075189", "PMID:31087249", "PMID:31170971", "PMID:32326025", "PMID:32368275", "PMID:32488807", "PMID:32651756" ; oboInOwl:hasExactSynonym "1beta,5,11alpha,14,19-pentahydroxy-17beta-(5-oxo-2,5-dihydrofuran-2-id-3-yl)-5beta,14beta-androstan-3beta-yl 6-deoxy-alpha-L-mannopyranoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ouabain", "ouabain anion" ; oboInOwl:id "CHEBI:145798" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ouabain(1-)" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_472805 ] . obo:CHEBI_146270 obo:IAO_0000115 "Any substance that produces or enhances dream-like states of consciousness." ; oboInOwl:hasDbXref "Wikipedia:Oneirogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oneirogens" ; oboInOwl:id "CHEBI:146270" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oneirogen" ; rdfs:subClassOf obo:CHEBI_35471 . obo:CHEBI_149484 obo:IAO_0000115 "A quinolinium ion obtained by protonation of the quinoline nitrogen and tertiary amino group of the antimalarial drug chloroquine. It is the major species at pH 7.3." ; chebi:charge "+2" ; chebi:formula "C18H28ClN3" ; chebi:inchi "InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)/p+2" ; chebi:inchikey "WHTVZRBIWZFKQO-UHFFFAOYSA-P" ; chebi:mass "321.890" ; chebi:monoisotopicmass "321.19608" ; chebi:smiles "[NH+]1=CC=C(C=2C1=CC(Cl)=CC2)NC(CCC[NH+](CC)CC)C" ; oboInOwl:hasDbXref "PMID:25693996" ; oboInOwl:hasExactSynonym "7-chloro-4-{[5-(diethylazaniumyl)pentan-2-yl]amino}quinolinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chloroquine dication", "di-protonated chloroquine" ; oboInOwl:id "CHEBI:149484" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chloroquine(2+)" ; rdfs:subClassOf obo:CHEBI_137982, obo:CHEBI_52837, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_3638 ] . obo:CHEBI_149548 obo:IAO_0000115 "An ammonium ion derivative obtained from protonation of the nitrogens of emetine. It is the major species at pH 7.3." ; chebi:charge "+2" ; chebi:formula "C29H42N2O4" ; chebi:inchi "InChI=1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/p+2/t18-,21-,24+,25-/m0/s1" ; chebi:inchikey "AUVVAXYIELKVAI-CKBKHPSWSA-P" ; chebi:mass "482.664" ; chebi:monoisotopicmass "482.31336" ; chebi:smiles "C=1C(=C(C=C2C1CC[NH+]3C[C@@H]([C@@](C[C@@]23[H])([H])C[C@@]4([H])[NH2+]CCC=5C4=CC(=C(C5)OC)OC)CC)OC)OC" ; oboInOwl:hasDbXref "MetaCyc:CPD-14817", "PMID:5985282" ; oboInOwl:hasExactSynonym "(2S)-6',7',10,11-tetramethoxyemetan-2',5-diium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "emetine dication" ; oboInOwl:id "CHEBI:149548" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "emetine(2+)" ; rdfs:subClassOf obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_4781 ] . obo:CHEBI_149552 obo:IAO_0000115 "Any agent that induces nausea and vomiting." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "emetics" ; oboInOwl:id "CHEBI:149552" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "emetic" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_149553 obo:IAO_0000115 "Any antiviral agent which inhibits the activity of coronaviruses." ; oboInOwl:hasDbXref "Wikipedia:Coronavirus" ; oboInOwl:hasExactSynonym "anticoronaviral agent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-coronaviral agent", "anti-coronaviral agents", "anti-coronavirus agent", "anti-coronavirus agents", "anticoronaviral agents", "anticoronaviral drug", "anticoronaviral drugs", "anticoronavirus agent", "anticoronavirus agents", "anticoronviral agent", "anticoronviral agents" ; oboInOwl:id "CHEBI:149553" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anticoronaviral agent" ; rdfs:subClassOf obo:CHEBI_22587 . obo:CHEBI_15138 obo:IAO_0000115 "A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide." ; chebi:charge "-2" ; chebi:formula "S" ; chebi:inchi "InChI=1S/S/q-2" ; chebi:inchikey "UCKMPCXJQFINFW-UHFFFAOYSA-N" ; chebi:mass "32.06600" ; chebi:monoisotopicmass "31.97317" ; chebi:smiles "[S--]" ; oboInOwl:hasDbXref "CAS:18496-25-8", "UM-BBD_compID:c0569" ; oboInOwl:hasExactSynonym "sulfanediide", "sulfide(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "S(2-)", "Sulfide", "sulphide" ; oboInOwl:id "CHEBI:15138" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfide(2-)" ; rdfs:subClassOf obo:CHEBI_79388, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29919 ] . obo:CHEBI_15318 obo:IAO_0000115 "A purine nucleobase found in humans and other organisms." ; chebi:charge "0" ; chebi:formula "C5H4N4O2" ; chebi:mass "152.111" ; chebi:monoisotopicmass "152.03343" ; oboInOwl:hasDbXref "ECMDB:ECMDB00292", "KNApSAcK:C00019660", "PMID:1557408", "PMID:24629268", "PMID:9007687", "YMDB:YMDB00263" ; oboInOwl:hasExactSynonym "xanthine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,6-dioxopurine", "2,6-dioxopurines", "xanthines" ; oboInOwl:id "CHEBI:15318" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "xanthine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25810, obo:CHEBI_26386, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16235 ] . obo:CHEBI_15339 obo:IAO_0000115 "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity." ; oboInOwl:hasAlternativeId "CHEBI:13699", "CHEBI:2377" ; oboInOwl:hasDbXref "KEGG:C00028", "KEGG:C16722" ; oboInOwl:hasExactSynonym "Acceptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "A", "Akzeptor", "Hydrogen-acceptor", "Oxidized donor", "accepteur" ; oboInOwl:id "CHEBI:15339" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acceptor" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_15347 obo:IAO_0000115 "A methyl ketone that consists of propane bearing an oxo group at C2." ; chebi:charge "0" ; chebi:formula "C3H6O" ; chebi:inchi "InChI=1S/C3H6O/c1-3(2)4/h1-2H3" ; chebi:inchikey "CSCPPACGZOOCGX-UHFFFAOYSA-N" ; chebi:mass "58.07914" ; chebi:monoisotopicmass "58.04186" ; chebi:smiles "CC(C)=O" ; oboInOwl:hasAlternativeId "CHEBI:13708", "CHEBI:22182", "CHEBI:2398", "CHEBI:40571" ; oboInOwl:hasDbXref "Beilstein:635680", "CAS:67-64-1", "Gmelin:1466", "HMDB:HMDB0001659", "KEGG:C00207", "KEGG:D02311", "LIPID_MAPS_instance:LMFA12000057", "MetaCyc:ACETONE", "PDBeChem:ACN", "PMID:17190852", "PMID:17347819", "Reaxys:635680", "UM-BBD_compID:c0556", "Wikipedia:Acetone" ; oboInOwl:hasExactSynonym "ACETONE", "Acetone", "acetone", "propan-2-one" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-Propanone", "Aceton", "Azeton", "Dimethyl ketone", "Dimethylketon", "Propanon", "Pyroacetic ether", "beta-Ketopropane", "dimethylcetone", "dimethylketone", "methyl ketone", "propanone" ; oboInOwl:id "CHEBI:15347" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acetone" ; rdfs:subClassOf obo:CHEBI_134179, obo:CHEBI_26292, obo:CHEBI_51867, obo:CHEBI_73693, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48358 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77941 ] . obo:CHEBI_15355 obo:IAO_0000115 "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter." ; chebi:charge "+1" ; chebi:formula "C7H16NO2" ; chebi:inchi "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1" ; chebi:inchikey "OIPILFWXSMYKGL-UHFFFAOYSA-N" ; chebi:mass "146.20748" ; chebi:monoisotopicmass "146.11756" ; chebi:smiles "CC(=O)OCC[N+](C)(C)C" ; oboInOwl:hasAlternativeId "CHEBI:12686", "CHEBI:13715", "CHEBI:22197", "CHEBI:2416", "CHEBI:40559" ; oboInOwl:hasDbXref "Beilstein:1764436", "CAS:51-84-3", "DrugBank:DB03128", "Drug_Central:65", "Gmelin:326108", "KEGG:C01996", "LINCS:LSM-5888", "PDBeChem:ACH", "PMID:14764638", "PMID:15014918", "PMID:15231705", "PMID:15361288", "PMID:18050502", "PMID:18407448", "PMID:19255787", "PMID:20963497", "PMID:21130809", "PMID:21246223", "PMID:21545631", "PMID:21601579", "Wikipedia:Acetylcholine" ; oboInOwl:hasExactSynonym "2-acetyloxy-N,N,N-trimethylethanaminium", "ACETYLCHOLINE", "Acetylcholine", "acetylcholine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ACh", "Azetylcholin", "O-Acetylcholine", "choline acetate" ; oboInOwl:id "CHEBI:15355" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acetylcholine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35287, obo:CHEBI_47622, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24621 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25512 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38325 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ] . obo:CHEBI_15356 obo:IAO_0000115 "A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3." ; chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "NC(CS)C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:14061", "CHEBI:23508", "CHEBI:4050" ; oboInOwl:hasDbXref "Beilstein:1721406", "CAS:3374-22-9", "Gmelin:2933", "KEGG:C00736", "KNApSAcK:C00001351", "KNApSAcK:C00007323", "PMID:17439666", "PMID:25181601", "Reaxys:1721406", "Wikipedia:Cysteine" ; oboInOwl:hasExactSynonym "Cysteine", "cysteine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-Amino-3-mercaptopropionic acid", "2-amino-3-mercaptopropanoic acid", "2-amino-3-sulfanylpropanoic acid", "C", "Cys", "Cystein", "Hcys", "Zystein", "cisteina" ; oboInOwl:id "CHEBI:15356" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cysteine" ; rdfs:subClassOf obo:CHEBI_26167, obo:CHEBI_26834, obo:CHEBI_33704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50326 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32456 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32458 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35237 ] . obo:CHEBI_15366 obo:IAO_0000115 "A simple monocarboxylic acid containing two carbons." ; chebi:charge "0" ; chebi:formula "C2H4O2" ; chebi:inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)" ; chebi:inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-N" ; chebi:mass "60.05200" ; chebi:monoisotopicmass "60.02113" ; chebi:smiles "CC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:22169", "CHEBI:2387", "CHEBI:40486" ; oboInOwl:hasDbXref "Beilstein:506007", "CAS:64-19-7", "Drug_Central:4211", "Gmelin:1380", "HMDB:HMDB0000042", "KEGG:C00033", "KEGG:D00010", "KNApSAcK:C00001176", "LIPID_MAPS_instance:LMFA01010002", "MetaCyc:ACET", "PDBeChem:ACT", "PDBeChem:ACY", "PMID:12005138", "PMID:15107950", "PMID:16630552", "PMID:16774200", "PMID:17190852", "PMID:19416101", "PMID:19469536", "PMID:22153255", "PMID:22173419", "PPDB:1333", "Reaxys:506007", "Wikipedia:Acetic_acid" ; oboInOwl:hasExactSynonym "ACETIC ACID", "Acetic acid", "acetic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "AcOH", "CH3-COOH", "CH3CO2H", "E 260", "E-260", "E260", "Essigsaeure", "Ethanoic acid", "Ethylic acid", "HOAc", "INS No. 260", "MeCO2H", "MeCOOH", "Methanecarboxylic acid", "acide acetique", "ethoic acid" ; oboInOwl:id "CHEBI:15366" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acetic acid" ; rdfs:subClassOf obo:CHEBI_25384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48356 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64049 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_65256 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30089 ] . obo:CHEBI_15422 obo:IAO_0000115 "An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways." ; chebi:charge "0" ; chebi:formula "C10H16N5O13P3" ; chebi:inchi "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "ZKHQWZAMYRWXGA-KQYNXXCUSA-N" ; chebi:mass "507.18100" ; chebi:monoisotopicmass "506.99575" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:10789", "CHEBI:10841", "CHEBI:13236", "CHEBI:22249", "CHEBI:2359", "CHEBI:40938" ; oboInOwl:hasDbXref "Beilstein:73010", "CAS:56-65-5", "DrugBank:DB00171", "Drug_Central:91", "Gmelin:34857", "HMDB:HMDB0000538", "KEGG:C00002", "KEGG:D08646", "KNApSAcK:C00001491", "PDBeChem:ATP", "Patent:US3079379", "Reaxys:73010", "Wikipedia:Adenosine_triphosphate" ; oboInOwl:hasExactSynonym "ATP", "adenosine 5'-(tetrahydrogen triphosphate)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ADENOSINE-5'-TRIPHOSPHATE", "Adenosine 5'-triphosphate", "Adenosine triphosphate", "H4atp" ; oboInOwl:id "CHEBI:15422" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ATP" ; rdfs:subClassOf obo:CHEBI_37045, obo:CHEBI_37096, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50733 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_57299 ] . obo:CHEBI_155837 obo:IAO_0000115 "A peptide zwitterion obtained from the tranfer of a proton from the carboxy group to the amino group of any tripeptide. It contains an equal number of positively-charged and negatively-charged functional groups. Major structure at pH 7.3." ; chebi:charge "0" ; chebi:formula "C6H8N3O4R3" ; chebi:mass "186.146" ; chebi:monoisotopicmass "186.05148" ; chebi:smiles "C(=O)([C@@H]([NH3+])*)N[C@H](C(=O)N[C@H](C(=O)[O-])*)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-amino acid tripeptide zwitterion", "L-amino acid tripeptide zwitterions", "amino acid tripeptide zwitterion", "amino acid tripeptide zwitterions", "an L-amino acid tripeptide" ; oboInOwl:id "CHEBI:155837" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tripeptide zwitterion" ; rdfs:subClassOf obo:CHEBI_60466, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_47923 ] . obo:CHEBI_15693 obo:IAO_0000115 "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals." ; chebi:charge "0" ; chebi:formula "C2H4O2(CH2O)n" ; oboInOwl:hasAlternativeId "CHEBI:13755", "CHEBI:22305", "CHEBI:2561" ; oboInOwl:hasDbXref "KEGG:C01370", "Wikipedia:Aldose" ; oboInOwl:hasExactSynonym "Aldose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldoses", "an aldose" ; oboInOwl:id "CHEBI:15693" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aldose" ; rdfs:subClassOf obo:CHEBI_35381 . obo:CHEBI_15705 obo:IAO_0000115 "Any alpha-amino acid having L-configuration at the alpha-carbon." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.05870" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "N[C@@H]([*])C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:13072", "CHEBI:13243", "CHEBI:13797", "CHEBI:21224", "CHEBI:6175" ; oboInOwl:hasDbXref "KEGG:C00151" ; oboInOwl:hasExactSynonym "L-alpha-amino acid", "L-alpha-amino acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-2-Amino acid", "L-Amino acid", "L-alpha-amino acids" ; oboInOwl:id "CHEBI:15705" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-alpha-amino acid" ; rdfs:subClassOf obo:CHEBI_33704, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_59814 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_59869 ] . obo:CHEBI_15734 obo:IAO_0000115 "A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it." ; chebi:charge "0" ; chebi:formula "CH3OR" ; chebi:mass "31.034" ; chebi:monoisotopicmass "31.01839" ; chebi:smiles "*C(O)([H])[H]" ; oboInOwl:hasAlternativeId "CHEBI:13676", "CHEBI:14887", "CHEBI:26262", "CHEBI:57489", "CHEBI:8406" ; oboInOwl:hasDbXref "KEGG:C00226" ; oboInOwl:hasExactSynonym "Primary alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-Alcohol", "a primary alcohol", "primary alcohols" ; oboInOwl:id "CHEBI:15734" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "primary alcohol" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_15740 obo:IAO_0000115 "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects." ; chebi:charge "-1" ; chebi:formula "CHO2" ; chebi:inchi "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1" ; chebi:inchikey "BDAGIHXWWSANSR-UHFFFAOYSA-M" ; chebi:mass "45.01744" ; chebi:monoisotopicmass "44.99820" ; chebi:smiles "[H]C([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:14276", "CHEBI:24081" ; oboInOwl:hasDbXref "Beilstein:1901205", "CAS:71-47-6", "Gmelin:1006", "HMDB:HMDB0000142", "KEGG:C00058", "MetaCyc:FORMATE", "PMID:17190852", "PMID:3946945", "Reaxys:1901205", "UM-BBD_compID:c0106", "Wikipedia:Formate" ; oboInOwl:hasExactSynonym "formate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HCO2 anion", "aminate", "formiate", "formic acid, ion(1-)", "formylate", "hydrogen carboxylate", "methanoate" ; oboInOwl:id "CHEBI:15740" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "formate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35757, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_30751 ] . obo:CHEBI_15837 obo:IAO_0000115 "An primary alcohol that is butan-1-ol in which a hydrogen at position 3 has been replaced by a methyl group." ; chebi:charge "0" ; chebi:formula "C5H12O" ; chebi:inchi "InChI=1S/C5H12O/c1-5(2)3-4-6/h5-6H,3-4H2,1-2H3" ; chebi:inchikey "PHTQWCKDNZKARW-UHFFFAOYSA-N" ; chebi:mass "88.14818" ; chebi:monoisotopicmass "88.08882" ; chebi:smiles "CC(C)CCO" ; oboInOwl:hasAlternativeId "CHEBI:11855", "CHEBI:1597", "CHEBI:20125", "CHEBI:43359" ; oboInOwl:hasDbXref "Beilstein:1718835", "CAS:123-51-3", "DrugBank:DB02296", "Gmelin:49460", "HMDB:HMDB0006007", "KEGG:C07328", "PMID:23043843", "PMID:23698045", "PMID:24487533", "PMID:24767042", "PMID:24804072", "PMID:24862930", "Reaxys:1718835", "YMDB:YMDB00570" ; oboInOwl:hasExactSynonym "3-methylbutan-1-ol", "isoamylol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-HYDROXY-3-METHYLBUTANE", "2-methyl-4-butanol", "3-Methylbutanol", "3-methyl-1-butanol", "3-methylbutanol", "Iso-amylalkohol", "Isoamyl alcohol", "Isopentyl alcohol", "Isopentylalkohol", "alcool isoamylique", "i-amyl alcohol", "isobutylcarbinol", "isopentan-1-ol", "isopentanol", "primary isoamyl alcohol" ; oboInOwl:id "CHEBI:15837" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isoamylol" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_134179, obo:CHEBI_15734, obo:CHEBI_50584, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35718 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76206 ], [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_30362 ] . obo:CHEBI_15854 obo:IAO_0000115 "A cinchona alkaloid that is cinchonidine in which the hydrogen at the 6-position of the quinoline ring is substituted by methoxy." ; chebi:charge "0" ; chebi:formula "C20H24N2O2" ; chebi:inchi "InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1" ; chebi:inchikey "LOUPRKONTZGTKE-WZBLMQSHSA-N" ; chebi:mass "324.41680" ; chebi:monoisotopicmass "324.18378" ; chebi:smiles "[H][C@]1(C[C@@H]2CC[N@]1C[C@@H]2C=C)[C@H](O)c1ccnc2ccc(OC)cc12" ; oboInOwl:hasAlternativeId "CHEBI:127176", "CHEBI:15001", "CHEBI:26499", "CHEBI:355947", "CHEBI:569215", "CHEBI:602929", "CHEBI:8723" ; oboInOwl:hasDbXref "Beilstein:91867", "CAS:130-95-0", "DrugBank:DB00468", "Drug_Central:4523", "KEGG:C06526", "KEGG:D08460", "KNApSAcK:C00002193", "PMID:10821711", "PMID:10891117", "PMID:10937718", "PMID:11212126", "PMID:11549443", "PMID:11728183", "PMID:11844668", "PMID:11855978", "PMID:12127529", "PMID:12213073", "PMID:12217353", "PMID:12477351", "PMID:12502361", "PMID:12798326", "PMID:12873511", "PMID:14761192", "PMID:15026051", "PMID:15027870", "PMID:15225721", "PMID:15857133", "PMID:16524728", "PMID:16933872", "PMID:17482816", "PMID:17506538", "PMID:17570664", "PMID:17850126", "PMID:18348514", "PMID:18788725", "PMID:2579237", "PMID:2657065", "PMID:7009867", "PMID:8182707", "Wikipedia:Quinine" ; oboInOwl:hasExactSynonym "(9R)-6'-methoxy-8alpha-cinchonan-9-ol", "Quinine", "quinine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-Quinine", "(-)-quinine", "(8S,9R)-quinine", "(R)-(-)-quinine", "(R)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methanol", "6'-methoxycinchonidine", "Chinin", "chinine", "chininum", "quinina" ; oboInOwl:id "CHEBI:15854" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "quinine" ; rdfs:subClassOf obo:CHEBI_51323, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35481 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_51371 ], [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_59138 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_137041 ] . obo:CHEBI_15858 chebi:charge "-1" ; chebi:formula "Br" ; chebi:inchi "InChI=1S/BrH/h1H/p-1" ; chebi:inchikey "CPELXLSAUQHCOX-UHFFFAOYSA-M" ; chebi:mass "79.90400" ; chebi:monoisotopicmass "78.91889" ; chebi:smiles "[Br-]" ; oboInOwl:hasAlternativeId "CHEBI:13918", "CHEBI:3178", "CHEBI:49515" ; oboInOwl:hasDbXref "Beilstein:3587179", "CAS:24959-67-9", "Gmelin:14908", "KEGG:C00720", "KEGG:C01324", "PDBeChem:BR" ; oboInOwl:hasExactSynonym "Bromide", "bromide", "bromide(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "BROMIDE ION", "Br(-)", "Br-", "bromine anion" ; oboInOwl:id "CHEBI:15858" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bromide" ; rdfs:subClassOf obo:CHEBI_16042, obo:CHEBI_36896, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_47266 ] . obo:CHEBI_15986 obo:IAO_0000115 "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues." ; chebi:charge "0" ; chebi:formula "(C5H8O6PR)n.C10H17O10PR2" ; oboInOwl:hasAlternativeId "CHEBI:13672", "CHEBI:14859", "CHEBI:8312" ; oboInOwl:hasDbXref "KEGG:C00419" ; oboInOwl:hasExactSynonym "Polynucleotide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polynucleotides" ; oboInOwl:id "CHEBI:15986" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polynucleotide" ; rdfs:subClassOf obo:CHEBI_33695, obo:CHEBI_61120, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50319 ] . obo:CHEBI_16042 obo:IAO_0000115 "A monoatomic monoanion resulting from the addition of an electron to any halogen atom." ; chebi:charge "-1" ; chebi:formula "X" ; chebi:mass "0.0" ; chebi:monoisotopicmass "0.0" ; chebi:smiles "[*-]" ; oboInOwl:hasAlternativeId "CHEBI:14384", "CHEBI:5605" ; oboInOwl:hasDbXref "KEGG:C00462" ; oboInOwl:hasExactSynonym "halide ions" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HX", "Halide", "a halide anion", "halide anions", "halide(1-)", "halides", "halogen anion" ; oboInOwl:id "CHEBI:16042" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halide anion" ; rdfs:subClassOf obo:CHEBI_33429, obo:CHEBI_79389 . obo:CHEBI_16133 obo:IAO_0000115 "The simplest member of the class of cyclopentanols bearing a single hydroxy substituent. The parent of the class of cyclopentanols." ; chebi:charge "0" ; chebi:formula "C5H10O" ; chebi:inchi "InChI=1S/C5H10O/c6-5-3-1-2-4-5/h5-6H,1-4H2" ; chebi:inchikey "XCIXKGXIYUWCLL-UHFFFAOYSA-N" ; chebi:mass "86.13230" ; chebi:monoisotopicmass "86.07316" ; chebi:smiles "OC1CCCC1" ; oboInOwl:hasAlternativeId "CHEBI:14057", "CHEBI:23494", "CHEBI:4022" ; oboInOwl:hasDbXref "CAS:96-41-3", "KEGG:C02020", "MetaCyc:CYCLOPENTANOL", "PMID:22145629", "PMID:24273356", "Reaxys:1900556", "Wikipedia:Cyclopentanol" ; oboInOwl:hasExactSynonym "Cyclopentanol", "cyclopentanol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cyclopentyl alcohol", "Hydroxycyclopentane" ; oboInOwl:id "CHEBI:16133" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclopentanol" ; rdfs:subClassOf obo:CHEBI_23495 . obo:CHEBI_16134 obo:IAO_0000115 "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms." ; chebi:charge "0" ; chebi:formula "H3N" ; chebi:inchi "InChI=1S/H3N/h1H3" ; chebi:inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-N" ; chebi:mass "17.03056" ; chebi:monoisotopicmass "17.02655" ; chebi:smiles "[H]N([H])[H]" ; oboInOwl:hasAlternativeId "CHEBI:13405", "CHEBI:13406", "CHEBI:13407", "CHEBI:13771", "CHEBI:22533", "CHEBI:44269", "CHEBI:44284", "CHEBI:44404", "CHEBI:7434" ; oboInOwl:hasDbXref "Beilstein:3587154", "CAS:7664-41-7", "Drug_Central:4625", "Gmelin:79", "HMDB:HMDB0000051", "KEGG:C00014", "KEGG:D02916", "KNApSAcK:C00007267", "MetaCyc:AMMONIA", "MolBase:930", "PDBeChem:NH3", "PMID:110589", "PMID:11139349", "PMID:11540049", "PMID:11746427", "PMID:11783653", "PMID:13753780", "PMID:14663195", "PMID:15092448", "PMID:15094021", "PMID:15554424", "PMID:15969015", "PMID:16008360", "PMID:16050680", "PMID:16348008", "PMID:16349403", "PMID:16614889", "PMID:16664306", "PMID:16842901", "PMID:17025297", "PMID:17439666", "PMID:17569513", "PMID:17737668", "PMID:18670398", "PMID:22002069", "PMID:22081570", "PMID:22088435", "PMID:22100291", "PMID:22130175", "PMID:22150211", "PMID:22240068", "PMID:22290316", "PMID:22342082", "PMID:22385337", "PMID:22443779", "PMID:22560242", "Reaxys:3587154", "Wikipedia:Ammonia" ; oboInOwl:hasExactSynonym "AMMONIA", "Ammonia", "ammonia", "azane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ammoniak", "NH3", "R-717", "[NH3]", "ammoniac", "amoniaco", "spirit of hartshorn" ; oboInOwl:id "CHEBI:16134" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ammonia" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_138675, obo:CHEBI_35107, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59740 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77941 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29337 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_28938 ] . obo:CHEBI_16136 obo:IAO_0000115 "A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen." ; chebi:charge "0" ; chebi:formula "H2S" ; chebi:inchi "InChI=1S/H2S/h1H2" ; chebi:inchikey "RWSOTUBLDIXVET-UHFFFAOYSA-N" ; chebi:mass "34.08188" ; chebi:monoisotopicmass "33.98772" ; chebi:smiles "[H]S[H]" ; oboInOwl:hasAlternativeId "CHEBI:13356", "CHEBI:14414", "CHEBI:24639", "CHEBI:43058", "CHEBI:45489", "CHEBI:5787" ; oboInOwl:hasDbXref "Beilstein:3535004", "CAS:7783-06-4", "Drug_Central:4260", "Gmelin:303", "KEGG:C00283", "KNApSAcK:C00007266", "MolBase:1709", "PDBeChem:H2S", "PMID:11788560", "PMID:14654297", "PMID:15003943", "PMID:15607739", "PMID:16446402", "PMID:18098324", "PMID:18524810", "PMID:18948540", "PMID:19695225", "PMID:22004989", "PMID:22378060", "PMID:22448627", "PMID:22473176", "PMID:22486842", "PMID:22520971", "PMID:22787557", "UM-BBD_compID:c0239", "Wikipedia:Hydrogen_sulfide" ; oboInOwl:hasExactSynonym "Hydrogen sulfide", "dihydridosulfur", "dihydrogen(sulfide)", "hydrogen sulfide", "sulfane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2S", "HYDROSULFURIC ACID", "Hydrogen-sulfide", "Schwefelwasserstoff", "Sulfide", "[SH2]", "acide sulfhydrique", "dihydrogen monosulfide", "dihydrogen sulfide", "hydrogen monosulfide", "hydrogen sulphide", "hydrogene sulfure", "sulfure d'hydrogene" ; oboInOwl:id "CHEBI:16136" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogen sulfide" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_33405, obo:CHEBI_33535, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27026 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_62488 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29919 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_30488 ] . obo:CHEBI_16183 obo:IAO_0000115 "A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC)." ; chebi:charge "0" ; chebi:formula "CH4" ; chebi:inchi "InChI=1S/CH4/h1H4" ; chebi:inchikey "VNWKTOKETHGBQD-UHFFFAOYSA-N" ; chebi:mass "16.04246" ; chebi:monoisotopicmass "16.03130" ; chebi:smiles "[H]C([H])([H])[H]" ; oboInOwl:hasAlternativeId "CHEBI:14585", "CHEBI:25220", "CHEBI:6811" ; oboInOwl:hasDbXref "Beilstein:1718732", "CAS:74-82-8", "Gmelin:59", "HMDB:HMDB0002714", "KEGG:C01438", "MetaCyc:CH4", "PMID:17791569", "PMID:23104415", "PMID:23353606", "PMID:23376302", "PMID:23397538", "PMID:23718889", "PMID:23739479", "PMID:23742231", "PMID:23756351", "PMID:24132456", "PMID:24161402", "PMID:24259373", "Patent:FR994032", "Patent:US2583090", "Reaxys:1718732", "UM-BBD_compID:c0095", "Wikipedia:Methane" ; oboInOwl:hasExactSynonym "Methane", "methane", "tetrahydridocarbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH4", "Methan", "marsh gas", "metano", "methyl hydride" ; oboInOwl:id "CHEBI:16183" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methane" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_138675, obo:CHEBI_18310, obo:CHEBI_37176, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35230 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76413 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76969 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29438 ] . obo:CHEBI_16199 obo:IAO_0000115 "A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O)." ; chebi:charge "0" ; chebi:formula "CH4N2O" ; chebi:inchi "InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)" ; chebi:inchikey "XSQUKJJJFZCRTK-UHFFFAOYSA-N" ; chebi:mass "60.05534" ; chebi:monoisotopicmass "60.03236" ; chebi:smiles "NC(N)=O" ; oboInOwl:hasAlternativeId "CHEBI:15292", "CHEBI:27218", "CHEBI:46379", "CHEBI:9888" ; oboInOwl:hasDbXref "Beilstein:635724", "CAS:57-13-6", "DrugBank:DB03904", "Drug_Central:4264", "ECMDB:ECMDB04172", "Gmelin:1378", "HMDB:HMDB0000294", "KEGG:C00086", "KEGG:D00023", "KNApSAcK:C00007314", "MetaCyc:UREA", "PDBeChem:URE", "PMID:18037357", "PMID:22770225", "PPDB:1728", "Reaxys:635724", "UM-BBD_compID:c0165", "Wikipedia:Urea", "YMDB:YMDB00003" ; oboInOwl:hasExactSynonym "UREA", "Urea", "urea" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1728", "Carbamide", "E927b", "H2NC(O)NH2", "Harnstoff", "Karbamid", "carbamide", "carbonyldiamide", "ur", "uree" ; oboInOwl:id "CHEBI:16199" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "urea" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_29347, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33287 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64577 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_28976 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_48376 ] . obo:CHEBI_16235 obo:IAO_0000115 "A 2-aminopurine carrying a 6-oxo substituent." ; chebi:charge "0" ; chebi:formula "C5H5N5O" ; chebi:inchi "InChI=1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)" ; chebi:inchikey "UYTPUPDQBNUYGX-UHFFFAOYSA-N" ; chebi:mass "151.126" ; chebi:monoisotopicmass "151.04941" ; chebi:smiles "C12=C(N=C(NC1=O)N)NC=N2" ; oboInOwl:hasAlternativeId "CHEBI:14371", "CHEBI:14372", "CHEBI:24443", "CHEBI:42948", "CHEBI:5563" ; oboInOwl:hasDbXref "Beilstein:147911", "CAS:73-40-5", "DrugBank:DB02377", "Gmelin:431879", "HMDB:HMDB0000132", "KEGG:C00242", "KNApSAcK:C00001501", "MetaCyc:GUANINE", "PDBeChem:GUN", "PMID:22770225", "PMID:8070089", "Reaxys:147911", "Wikipedia:Guanine" ; oboInOwl:hasExactSynonym "2-amino-1,9-dihydro-6H-purin-6-one", "GUANINE", "Guanine", "guanine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-Amino-6-hydroxypurine", "2-amino-6-oxopurine", "G", "Gua" ; oboInOwl:id "CHEBI:16235" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "guanine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_20702, obo:CHEBI_25810, obo:CHEBI_26386, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84735 ], [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_16236 obo:IAO_0000115 "A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group." ; chebi:charge "0" ; chebi:formula "C2H6O" ; chebi:inchi "InChI=1S/C2H6O/c1-2-3/h3H,2H2,1H3" ; chebi:inchikey "LFQSCWFLJHTTHZ-UHFFFAOYSA-N" ; chebi:mass "46.06844" ; chebi:monoisotopicmass "46.04186" ; chebi:smiles "CCO" ; oboInOwl:hasAlternativeId "CHEBI:14222", "CHEBI:23978", "CHEBI:30878", "CHEBI:30880", "CHEBI:42377", "CHEBI:44594", "CHEBI:4879" ; oboInOwl:hasDbXref "Beilstein:1718733", "CAS:64-17-5", "DrugBank:DB00898", "Drug_Central:1076", "Gmelin:787", "HMDB:HMDB0000108", "KEGG:C00469", "KEGG:D00068", "KEGG:D06542", "KNApSAcK:C00019560", "MetaCyc:ETOH", "MolBase:858", "MolBase:859", "PDBeChem:EOH", "PMID:11046114", "PMID:11090978", "PMID:11198720", "PMID:11200745", "PMID:11262320", "PMID:11303910", "PMID:11333032", "PMID:11505026", "PMID:11590970", "PMID:11728426", "PMID:11750186", "PMID:11754521", "PMID:11810019", "PMID:11826039", "PMID:11981228", "PMID:12824058", "PMID:12829422", "PMID:12888778", "PMID:12946583", "PMID:14674846", "PMID:15019421", "PMID:15239123", "PMID:15285839", "PMID:15464411", "PMID:15465973", "PMID:15749123", "PMID:15900217", "PMID:15902919", "PMID:16084479", "PMID:16133132", "PMID:16352430", "PMID:16390872", "PMID:16737463", "PMID:16891664", "PMID:16934862", "PMID:17043811", "PMID:17190852", "PMID:17663926", "PMID:17687877", "PMID:18095657", "PMID:18249266", "PMID:18320157", "PMID:18347649", "PMID:18408978", "PMID:18411066", "PMID:18456322", "PMID:18513832", "PMID:18922656", "PMID:18925476", "PMID:19280886", "PMID:19359288", "PMID:19384566", "PMID:19458312", "PMID:19851413", "PMID:19901811", "PMID:21600756", "PMID:21762181", "PMID:21881875", "PMID:21967628", "PMID:22019193", "PMID:22222864", "PMID:22261437", "PMID:22286266", "PMID:22306018", "PMID:22331491", "PMID:22336593", "PPDB:1373", "Reaxys:1718733", "UM-BBD_compID:c0038", "Wikipedia:Ethanol" ; oboInOwl:hasExactSynonym "ETHANOL", "Ethanol", "ethanol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-hydroxyethane", "Aethanol", "Aethylalkohol", "Alkohol", "C2H5OH", "Dehydrated ethanol", "EtOH", "Ethyl alcohol", "Methylcarbinol", "[CH2Me(OH)]", "[OEtH]", "alcohol", "alcohol etilico", "alcool ethylique", "etanol", "hydroxyethane", "spiritus vini" ; oboInOwl:id "CHEBI:16236" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ethanol" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_134179, obo:CHEBI_23982, obo:CHEBI_50584, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35488 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48218 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48219 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48354 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_60643 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64018 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_52092 ] . obo:CHEBI_16240 obo:IAO_0000115 "An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond." ; chebi:charge "0" ; chebi:formula "H2O2" ; chebi:inchi "InChI=1S/H2O2/c1-2/h1-2H" ; chebi:inchikey "MHAJPDPJQMAIIY-UHFFFAOYSA-N" ; chebi:mass "34.01468" ; chebi:monoisotopicmass "34.00548" ; chebi:smiles "[H]OO[H]" ; oboInOwl:hasAlternativeId "CHEBI:13354", "CHEBI:13355", "CHEBI:24637", "CHEBI:44812", "CHEBI:5586" ; oboInOwl:hasDbXref "Beilstein:3587191", "CAS:7722-84-1", "Drug_Central:3281", "Gmelin:509", "HMDB:HMDB0003125", "KEGG:C00027", "KEGG:D00008", "MetaCyc:HYDROGEN-PEROXIDE", "MolBase:932", "PDBeChem:PEO", "PMID:10455187", "PMID:10557015", "PMID:10849784", "PMID:11033421", "PMID:11105916", "PMID:11318558", "PMID:11387393", "PMID:11809417", "PMID:11864786", "PMID:11893576", "PMID:12867293", "PMID:12934880", "PMID:14679422", "PMID:15028418", "PMID:15133946", "PMID:15298493", "PMID:16337875", "PMID:16463018", "PMID:16864869", "PMID:17020896", "PMID:17179007", "PMID:17610934", "PMID:17948137", "PMID:18179203", "PMID:18182702", "PMID:18306736", "PMID:18443210", "PMID:18592736", "PMID:19107210", "PMID:19229032", "PMID:19297450", "PMID:19509065", "PMID:26352695", "PMID:26365231", "PMID:7548021", "PMID:7581816", "PMID:8048546", "PMID:8375042", "PMID:8451754", "PMID:9051670", "PMID:9100841", "PMID:9168257", "PMID:9202721", "PMID:9558114", "PPDB:387", "Reaxys:3587191", "Wikipedia:Hydrogen_peroxide" ; oboInOwl:hasExactSynonym "HYDROGEN PEROXIDE", "Hydrogen peroxide", "bis(hydridooxygen)(O--O)", "dihydrogen peroxide", "dihydrogen(peroxide)", "dioxidane", "hydrogen peroxide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2O2", "HOOH", "Oxydol", "[OH(OH)]", "dihydrogen dioxide", "perhydrol" ; oboInOwl:id "CHEBI:16240" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogen peroxide" ; rdfs:subClassOf obo:CHEBI_24837, obo:CHEBI_26523, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_132717 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149552 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48219 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59163 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63490 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_65259 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_68495 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76967 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29192 ] . obo:CHEBI_16247 obo:IAO_0000115 "A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides." ; oboInOwl:hasAlternativeId "CHEBI:14816", "CHEBI:26063", "CHEBI:8150" ; oboInOwl:hasDbXref "KEGG:C00865" ; oboInOwl:hasExactSynonym "Phospholipid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a phospholipid derivative", "phospholipids" ; oboInOwl:id "CHEBI:16247" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phospholipid" ; rdfs:subClassOf obo:CHEBI_18059, obo:CHEBI_25703, obo:CHEBI_37734, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_62643 ] . obo:CHEBI_16335 obo:IAO_0000115 "A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond." ; chebi:charge "0" ; chebi:formula "C10H13N5O4" ; chebi:inchi "InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "OIRDTQYFTABQOQ-KQYNXXCUSA-N" ; chebi:mass "267.24152" ; chebi:monoisotopicmass "267.09675" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:13734", "CHEBI:22237", "CHEBI:2472", "CHEBI:40558", "CHEBI:40825", "CHEBI:40906" ; oboInOwl:hasDbXref "Beilstein:93029", "CAS:58-61-7", "DrugBank:DB00640", "Drug_Central:90", "ECMDB:ECMDB00050", "Gmelin:53385", "HMDB:HMDB0000050", "KEGG:C00212", "KEGG:D00045", "KNApSAcK:C00007444", "LINCS:LSM-28568", "MetaCyc:ADENOSINE", "PDBeChem:ADN", "PMID:11213237", "PMID:11820865", "PMID:11978011", "PMID:16183671", "PMID:16917093", "PMID:17190852", "PMID:18000974", "PMID:323854", "Reaxys:93029", "Wikipedia:Adenosine", "YMDB:YMDB00058" ; oboInOwl:hasExactSynonym "ADENOSINE", "Adenosine", "adenosine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol", "6-Amino-9-beta-D-ribofuranosyl-9H-purine", "9-beta-D-Ribofuranosidoadenine", "9-beta-D-Ribofuranosyl-9H-purin-6-amine", "9-beta-D-ribofuranosyl-9H-purin-6-amine", "Ade-Rib", "Adenine Deoxyribonucleoside", "Adenocard", "Adenocor", "Adenoscan", "Adenosin", "Adenyldeoxyriboside", "Ado", "Deoxyadenosine", "Desoxyadenosine", "beta-D-Adenosine" ; oboInOwl:id "CHEBI:16335" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adenosine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_142355, obo:CHEBI_22260, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35480 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38070 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ] . obo:CHEBI_16375 obo:IAO_0000115 "An optically active form of cysteine having D-configuration." ; chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "N[C@H](CS)C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:12919", "CHEBI:20921", "CHEBI:4111", "CHEBI:41887" ; oboInOwl:hasDbXref "Beilstein:1721407", "CAS:921-01-7", "DrugBank:DB03201", "ECMDB:ECMDB03417", "Gmelin:363236", "HMDB:HMDB0003417", "KEGG:C00793", "KNApSAcK:C00007323", "PDBeChem:DCY", "PMID:13761469", "PMID:23340406", "PMID:24800864", "Reaxys:1721407", "YMDB:YMDB00913" ; oboInOwl:hasExactSynonym "D-CYSTEINE", "D-Cysteine", "D-cysteine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2S)-2-amino-3-mercaptopropanoic acid", "(2S)-2-amino-3-sulfanylpropanoic acid", "(S)-2-amino-3-mercaptopropanoic acid", "D-Amino-3-mercaptopropionic acid", "D-Cystein", "D-Zystein", "DCY" ; oboInOwl:id "CHEBI:16375" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-cysteine" ; rdfs:subClassOf obo:CHEBI_15356, obo:CHEBI_16733, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32449 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32451 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_17561 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35236 ] . obo:CHEBI_16382 chebi:charge "-1" ; chebi:formula "I" ; chebi:inchi "InChI=1S/HI/h1H/p-1" ; chebi:inchikey "XMBWDFGMSWQBCA-UHFFFAOYSA-M" ; chebi:mass "126.90447" ; chebi:monoisotopicmass "126.90502" ; chebi:smiles "[I-]" ; oboInOwl:hasAlternativeId "CHEBI:14460", "CHEBI:49698", "CHEBI:5946" ; oboInOwl:hasDbXref "Beilstein:3587184", "CAS:20461-54-5", "Gmelin:14912", "KEGG:C00708", "PDBeChem:IOD" ; oboInOwl:hasExactSynonym "Iodide", "iodide", "iodide(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "I(-)", "I-", "IODIDE ION", "iodine anion" ; oboInOwl:id "CHEBI:16382" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iodide" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_16042, obo:CHEBI_36897, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_43451 ] . obo:CHEBI_16385 obo:IAO_0000115 "Compounds having the structure RSR (R =/= H). Such compounds were once called thioethers." ; chebi:charge "0" ; chebi:formula "SR2" ; chebi:mass "32.066" ; chebi:monoisotopicmass "31.97207" ; oboInOwl:hasAlternativeId "CHEBI:13694", "CHEBI:26960", "CHEBI:9340" ; oboInOwl:hasDbXref "KEGG:C00297" ; oboInOwl:hasExactSynonym "sulfides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RSR", "Sulfide", "Thioether", "organic sulfides", "thioethers" ; oboInOwl:id "CHEBI:16385" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic sulfide" ; rdfs:subClassOf obo:CHEBI_26822, obo:CHEBI_33261 . obo:CHEBI_16526 obo:IAO_0000115 "A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food." ; chebi:charge "0" ; chebi:formula "CO2" ; chebi:inchi "InChI=1S/CO2/c2-1-3" ; chebi:inchikey "CURLTUGMZLYLDI-UHFFFAOYSA-N" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "O=C=O" ; oboInOwl:hasAlternativeId "CHEBI:13282", "CHEBI:13283", "CHEBI:13284", "CHEBI:13285", "CHEBI:23011", "CHEBI:3283", "CHEBI:48829" ; oboInOwl:hasDbXref "Beilstein:1900390", "CAS:124-38-9", "Drug_Central:4256", "Gmelin:989", "HMDB:HMDB0001967", "KEGG:C00011", "KEGG:D00004", "MetaCyc:CARBON-DIOXIDE", "MolBase:752", "PDBeChem:CO2", "PMID:10826146", "PMID:11094503", "PMID:11584085", "PMID:11802652", "PMID:14639145", "PMID:15050588", "PMID:16591971", "PMID:16656478", "PMID:16659660", "PMID:17190796", "PMID:17448243", "PMID:17878298", "PMID:17884085", "PMID:19043767", "PMID:19259576", "PMID:19854893", "PMID:23384758", "PMID:23828359", "PMID:24258718", "PMID:8482095", "PMID:8818713", "PMID:8869828", "PMID:9611769", "PMID:9730350", "PPDB:119", "Reaxys:1900390", "UM-BBD_compID:c0131", "Wikipedia:Carbon_dioxide" ; oboInOwl:hasExactSynonym "CARBON DIOXIDE", "Carbon dioxide", "carbon dioxide", "dioxidocarbon", "methanedione" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CO2", "E 290", "E-290", "E290", "R-744", "[CO2]", "carbonic anhydride" ; oboInOwl:id "CHEBI:16526" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbon dioxide" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_138675, obo:CHEBI_23014, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38867 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48706 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76413 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77974 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78017 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_16555 obo:IAO_0000115 "A thioacetic acid that is acetic acid in which the oxygen atom of the hydroxy group has been replaced by a sulfur atom." ; chebi:charge "0" ; chebi:formula "C2H4OS" ; chebi:inchi "InChI=1S/C2H4OS/c1-2(3)4/h1H3,(H,3,4)" ; chebi:inchikey "DUYAAUVXQSMXQP-UHFFFAOYSA-N" ; chebi:mass "76.11856" ; chebi:monoisotopicmass "75.99829" ; chebi:smiles "CC(S)=O" ; oboInOwl:hasAlternativeId "CHEBI:9547" ; oboInOwl:hasDbXref "Beilstein:773684", "CAS:507-09-5", "Gmelin:49262", "KEGG:C01857", "PMID:23298036", "Reaxys:773684" ; oboInOwl:hasExactSynonym "ethanethioic S-acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3COSH", "Thioacetic acid", "acetyl mercaptan", "thioacetic S-acid" ; oboInOwl:id "CHEBI:16555" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ethanethioic S-acid" ; rdfs:subClassOf obo:CHEBI_26952, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_46800 ] . obo:CHEBI_16583 obo:IAO_0000115 "An alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation." ; chebi:charge "0" ; chebi:formula "C4H6O2" ; chebi:inchi "InChI=1S/C4H6O2/c1-3(5)4(2)6/h1-2H3" ; chebi:inchikey "QSJXEFYPDANLFS-UHFFFAOYSA-N" ; chebi:mass "86.08924" ; chebi:monoisotopicmass "86.03678" ; chebi:smiles "CC(=O)C(C)=O" ; oboInOwl:hasAlternativeId "CHEBI:14134", "CHEBI:4479" ; oboInOwl:hasDbXref "Beilstein:605398", "CAS:431-03-8", "HMDB:HMDB0003407", "KEGG:C00741", "PMID:15654607", "PMID:24614328", "Reaxys:605398" ; oboInOwl:hasExactSynonym "butane-2,3-dione" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,3-Butadione", "2,3-Butanedione", "2,3-Diketobutane", "2,3-Dioxobutane", "2,3-butandione", "Biacetyl", "Diacetyl", "Dimethyl glyoxal", "Dimethylglyoxal", "diacetyl" ; oboInOwl:id "CHEBI:16583" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "butane-2,3-dione" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_51869, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_16646 obo:IAO_0000115 "Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates." ; oboInOwl:hasAlternativeId "CHEBI:15131", "CHEBI:23008", "CHEBI:9318" ; oboInOwl:hasDbXref "Wikipedia:Carbohydrate" ; oboInOwl:hasExactSynonym "carbohydrate", "carbohydrates" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kohlenhydrat", "Kohlenhydrate", "a carbohydrate", "carbohidrato", "carbohidratos", "glucide", "glucides", "glucido", "glucidos", "hydrates de carbone", "saccharide", "saccharides", "saccharidum" ; oboInOwl:id "CHEBI:16646" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbohydrate" ; rdfs:subClassOf obo:CHEBI_78616 . obo:CHEBI_16670 obo:IAO_0000115 "Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc." ; chebi:charge "0" ; chebi:formula "(C2H2NOR)nC2H3NOR" ; oboInOwl:hasAlternativeId "CHEBI:14753", "CHEBI:25906", "CHEBI:7990" ; oboInOwl:hasDbXref "KEGG:C00012" ; oboInOwl:hasExactSynonym "Peptide", "peptides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Peptid", "peptido", "peptidos" ; oboInOwl:id "CHEBI:16670" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "peptide" ; rdfs:subClassOf obo:CHEBI_37622, obo:CHEBI_50047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33708 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_60466 ] . obo:CHEBI_16701 obo:IAO_0000115 "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-5 of the ribose ring is mono-, di-, tri- or tetra-phosphorylated." ; chebi:charge "0" ; chebi:formula "C5H9O6PR2" ; chebi:mass "196.09510" ; chebi:monoisotopicmass "196.01367" ; chebi:smiles "O[C@H]1[C@@H]([*])[C@H]([*])O[C@@H]1COP(O)(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:14674", "CHEBI:25603", "CHEBI:7650" ; oboInOwl:hasDbXref "KEGG:C01117" ; oboInOwl:hasExactSynonym "Nucleoside 5'-phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleoside 5'-phosphates" ; oboInOwl:id "CHEBI:16701" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-phosphate" ; rdfs:subClassOf obo:CHEBI_29075, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_57867 ] . obo:CHEBI_16708 obo:IAO_0000115 "The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6." ; chebi:charge "0" ; chebi:formula "C5H5N5" ; chebi:inchi "InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)" ; chebi:inchikey "GFFGJBXGBJISGV-UHFFFAOYSA-N" ; chebi:mass "135.12690" ; chebi:monoisotopicmass "135.05450" ; chebi:smiles "Nc1ncnc2[nH]cnc12" ; oboInOwl:hasAlternativeId "CHEBI:13733", "CHEBI:22236", "CHEBI:2470", "CHEBI:40579" ; oboInOwl:hasDbXref "Beilstein:608603", "CAS:73-24-5", "DrugBank:DB00173", "Drug_Central:89", "Gmelin:3903", "HMDB:HMDB0000034", "KEGG:C00147", "KEGG:D00034", "KNApSAcK:C00001490", "MetaCyc:ADENINE", "PDBeChem:ADE", "PMID:11985597", "PMID:12829005", "PMID:12951489", "PMID:15063338", "PMID:15715490", "PMID:17439666", "PMID:8070089", "Reaxys:608603", "Wikipedia:Adenine" ; oboInOwl:hasExactSynonym "9H-purin-6-amine", "ADENINE", "Adenine", "adenine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "6-Aminopurine", "A", "Ade", "Adenin" ; oboInOwl:id "CHEBI:16708" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adenine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_20706, obo:CHEBI_26386, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_16733 chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.05870" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "N[C@H]([*])C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:12909", "CHEBI:13625", "CHEBI:20906", "CHEBI:4097" ; oboInOwl:hasDbXref "KEGG:C00405" ; oboInOwl:hasExactSynonym "D-alpha-amino acid", "D-alpha-amino acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "D-Amino acid", "D-alpha-amino acids" ; oboInOwl:id "CHEBI:16733" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-alpha-amino acid" ; rdfs:subClassOf obo:CHEBI_83925, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_60895 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_59871 ] . obo:CHEBI_167559 obo:IAO_0000115 "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glycans" ; oboInOwl:id "CHEBI:167559" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glycan" ; rdfs:subClassOf obo:CHEBI_78616 . obo:CHEBI_16765 obo:IAO_0000115 "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position." ; chebi:charge "0" ; chebi:formula "C10H12N2" ; chebi:inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2" ; chebi:inchikey "APJYDQYYACXCRM-UHFFFAOYSA-N" ; chebi:mass "160.21570" ; chebi:monoisotopicmass "160.10005" ; chebi:smiles "NCCc1c[nH]c2ccccc12" ; oboInOwl:hasAlternativeId "CHEBI:15274", "CHEBI:27161", "CHEBI:46157", "CHEBI:9767" ; oboInOwl:hasDbXref "Beilstein:125513", "CAS:61-54-1", "DrugBank:DB08653", "Gmelin:603448", "HMDB:HMDB0000303", "KEGG:C00398", "KNApSAcK:C00001434", "MetaCyc:TRYPTAMINE", "PDBeChem:TSS", "PMID:16126914", "PMID:22770225", "PMID:24345948", "PMID:24558969", "Reaxys:125513", "Wikipedia:Tryptamine" ; oboInOwl:hasExactSynonym "2-(1H-indol-3-yl)ethanamine", "Tryptamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1H-indole-3-ethanamine", "2-(1H-INDOL-3-YL)ETHANAMINE", "2-(3-indolyl)ethylamine", "3-(2-Aminoethyl)indole" ; oboInOwl:id "CHEBI:16765" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tryptamine" ; rdfs:subClassOf obo:CHEBI_27162, obo:CHEBI_38631, obo:CHEBI_38958, obo:CHEBI_64365, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_57887 ] . obo:CHEBI_16856 obo:IAO_0000115 "A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine." ; chebi:charge "0" ; chebi:formula "C10H17N3O6S" ; chebi:inchi "InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1" ; chebi:inchikey "RWSXRVCMGQZWBV-WDSKDSINSA-N" ; chebi:mass "307.320" ; chebi:monoisotopicmass "307.08381" ; chebi:smiles "N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O" ; oboInOwl:hasAlternativeId "CHEBI:12402", "CHEBI:14327", "CHEBI:24334", "CHEBI:42873", "CHEBI:43049", "CHEBI:5437" ; oboInOwl:hasDbXref "CAS:70-18-8", "Chemspider:111188", "DrugBank:DB00143", "Drug_Central:1312", "FooDB:FDB001498", "HMDB:HMDB0000125", "KEGG:C00051", "KEGG:D00014", "KNApSAcK:C00001518", "MetaCyc:GLUTATHIONE", "PDBeChem:GSH", "PMID:10577998", "PMID:1362956", "PMID:14988435", "PMID:16112416", "PMID:16316931", "PMID:16391576", "PMID:16404476", "PMID:16621738", "PMID:16650398", "PMID:16780237", "PMID:16877380", "PMID:17439666", "PMID:19580823", "PMID:4200890", "PMID:4745654", "PMID:8207209", "Reaxys:1729812", "Wikipedia:Glutathione" ; oboInOwl:hasExactSynonym "Glutathione", "L-gamma-glutamyl-L-cysteinylglycine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-L-Glutamyl-L-cysteinylglycine", "GSH", "Glutathione-SH", "N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine", "Reduced glutathione", "gamma-L-Glutamyl-L-cysteinyl-glycine" ; oboInOwl:id "CHEBI:16856" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glutathione" ; rdfs:subClassOf obo:CHEBI_29256, obo:CHEBI_47923, obo:CHEBI_83824, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22586 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_85046 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_57925 ] . obo:CHEBI_16865 obo:IAO_0000115 "A gamma-amino acid that is butanoic acid with the amino substituent located at C-4." ; chebi:charge "0" ; chebi:formula "C4H9NO2" ; chebi:inchi "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" ; chebi:inchikey "BTCSSZJGUNDROE-UHFFFAOYSA-N" ; chebi:mass "103.11980" ; chebi:monoisotopicmass "103.06333" ; chebi:smiles "NCCCC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:1786", "CHEBI:193777", "CHEBI:20318", "CHEBI:40483" ; oboInOwl:hasDbXref "BPDB:2298", "Beilstein:906818", "CAS:56-12-2", "DrugBank:DB02530", "Drug_Central:1262", "Gmelin:49775", "HMDB:HMDB0000112", "KEGG:C00334", "KEGG:D00058", "KNApSAcK:C00001337", "LIPID_MAPS_instance:LMFA01100039", "MetaCyc:4-AMINO-BUTYRATE", "PDBeChem:ABU", "PMID:10630630", "PMID:10930630", "PMID:16276116", "PMID:21614609", "PMID:22770225", "Reaxys:906818", "Wikipedia:Gamma-Aminobutyric_acid" ; oboInOwl:hasExactSynonym "4-aminobutanoic acid", "gamma-Aminobutyric acid", "gamma-aminobutyric acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-Aminobutanoic acid", "4-Aminobutyric acid", "4-aminobutanoic acid", "4-aminobutyric acid", "4Abu", "GABA", "GAMMA-AMINO-BUTANOIC ACID", "gamma-Aminobuttersaeure", "gamma-amino-n-butyric acid", "gamma-aminobutanoic acid", "omega-aminobutyric acid", "piperidic acid", "piperidinic acid" ; oboInOwl:id "CHEBI:16865" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "gamma-aminobutyric acid" ; rdfs:subClassOf obo:CHEBI_25384, obo:CHEBI_33707, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25512 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_62488 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_30772 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30566 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_59888 ] . obo:CHEBI_16988 obo:IAO_0000115 "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in D-glyceraldehyde." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:mass "150.12990" ; chebi:monoisotopicmass "150.05282" ; oboInOwl:hasAlternativeId "CHEBI:13011", "CHEBI:21078" ; oboInOwl:hasDbXref "DrugBank:DB01936", "PMID:24404872", "PMID:24752650" ; oboInOwl:hasExactSynonym "D-ribo-pentose", "D-ribose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "D-Rib" ; oboInOwl:id "CHEBI:16988" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-ribose" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33942, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_46997 ] . obo:CHEBI_17051 chebi:charge "-1" ; chebi:formula "F" ; chebi:inchi "InChI=1S/FH/h1H/p-1" ; chebi:inchikey "KRHYYFGTRYWZRS-UHFFFAOYSA-M" ; chebi:mass "18.99840" ; chebi:monoisotopicmass "18.99895" ; chebi:smiles "[F-]" ; oboInOwl:hasAlternativeId "CHEBI:14271", "CHEBI:49593", "CHEBI:5113" ; oboInOwl:hasDbXref "CAS:16984-48-8", "Gmelin:14905", "KEGG:C00742", "PDBeChem:F" ; oboInOwl:hasExactSynonym "Fluoride", "fluoride", "fluoride(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "F(-)", "F-", "FLUORIDE ION", "Fluoride ion", "Fluorine anion" ; oboInOwl:id "CHEBI:17051" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluoride" ; rdfs:subClassOf obo:CHEBI_16042, obo:CHEBI_36895, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29228 ] . obo:CHEBI_17062 chebi:charge "0" ; chebi:formula "CH4NR" ; chebi:mass "30.04920" ; chebi:monoisotopicmass "30.03437" ; chebi:smiles "NC[*]" ; oboInOwl:hasAlternativeId "CHEBI:13431", "CHEBI:8749" ; oboInOwl:hasDbXref "KEGG:C00375" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RCH2NH2", "primary aliphatic amines" ; oboInOwl:id "CHEBI:17062" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "primary aliphatic amine" ; rdfs:subClassOf obo:CHEBI_32877, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_58001 ] . obo:CHEBI_17087 obo:IAO_0000115 "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H)." ; chebi:charge "0" ; chebi:formula "COR2" ; chebi:mass "28.010" ; chebi:monoisotopicmass "27.99491" ; chebi:smiles "[*]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13427", "CHEBI:13646", "CHEBI:24974", "CHEBI:6127", "CHEBI:8742" ; oboInOwl:hasDbXref "KEGG:C01450", "Wikipedia:Ketone" ; oboInOwl:hasExactSynonym "Ketone", "ketones" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Keton", "R-CO-R'", "a ketone", "cetone", "ketones" ; oboInOwl:id "CHEBI:17087" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ketone" ; rdfs:subClassOf obo:CHEBI_36586 . obo:CHEBI_17120 obo:IAO_0000115 "A short-chain fatty acid anion that is the conjugate base of hexanoic acid (also known as caproic acid)." ; chebi:charge "-1" ; chebi:formula "C6H11O2" ; chebi:inchi "InChI=1S/C6H12O2/c1-2-3-4-5-6(7)8/h2-5H2,1H3,(H,7,8)/p-1" ; chebi:inchikey "FUZZWVXGSFPDMH-UHFFFAOYSA-M" ; chebi:mass "115.15034" ; chebi:monoisotopicmass "115.07645" ; chebi:smiles "CCCCCC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:14398", "CHEBI:24569" ; oboInOwl:hasDbXref "Beilstein:3601453", "CAS:151-33-7", "ECMDB:ECMDB21229", "Gmelin:326340", "KEGG:C01585", "MetaCyc:HEXANOATE" ; oboInOwl:hasExactSynonym "hexanoate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-hexanoate", "1-pentacarboxylate", "1-pentanecarboxylate", "CH3-[CH2]4-COO(-)", "butylacetate", "caproate", "capronate", "hexoate", "hexylate", "n-caproate", "n-hexanoate", "n-hexoate", "n-hexylate", "nPnCO2 anion", "pentanecarboxylate", "pentylformate" ; oboInOwl:id "CHEBI:17120" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hexanoate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_58951, obo:CHEBI_58954, obo:CHEBI_78116, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_30776 ] . obo:CHEBI_17134 obo:IAO_0000115 "A member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates." ; chebi:charge "0" ; chebi:formula "C8H11NO2" ; chebi:inchi "InChI=1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2" ; chebi:inchikey "QHGUCRYDKWKLMG-UHFFFAOYSA-N" ; chebi:mass "153.17848" ; chebi:monoisotopicmass "153.07898" ; chebi:smiles "NCC(O)c1ccc(O)cc1" ; oboInOwl:hasAlternativeId "CHEBI:11191", "CHEBI:25655", "CHEBI:571" ; oboInOwl:hasDbXref "Beilstein:1211019", "CAS:104-14-3", "Drug_Central:3396", "KEGG:C04227", "LINCS:LSM-4975" ; oboInOwl:hasExactSynonym "4-(2-amino-1-hydroxyethyl)phenol", "Octopamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-(4-Hydroxyphenyl)-2-aminoethanol", "1-(p-hydroxyphenyl)-2-aminoethanol", "Octopamin", "alpha-(aminomethyl)-4-hydroxybenzenemethanol", "alpha-(aminomethyl)-p-hydroxybenzyl alcohol", "beta-hydroxytyramine", "norsynephrine", "octopaminum", "p-Hydroxyphenylethanolamine" ; oboInOwl:id "CHEBI:17134" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "octopamine" ; rdfs:subClassOf obo:CHEBI_25990, obo:CHEBI_27175, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25512 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_58025 ] . obo:CHEBI_17137 chebi:charge "-1" ; chebi:formula "HO3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-1" ; chebi:inchikey "LSNNMFCWUKXFEE-UHFFFAOYSA-M" ; chebi:mass "81.07214" ; chebi:monoisotopicmass "80.96519" ; chebi:smiles "OS([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:13367", "CHEBI:5598" ; oboInOwl:hasDbXref "CAS:15181-46-1", "Gmelin:1455", "KEGG:C11481", "PDBeChem:SO3" ; oboInOwl:hasExactSynonym "hydrogen(trioxidosulfate)(1-)", "hydrogensulfite(1-)", "hydrogentrioxosulfate(1-)", "hydrogentrioxosulfate(IV)", "hydroxidodioxidosulfate(1-)", "monohydrogentrioxosulfate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bisulfite", "HSO3(-)", "HSO3-", "Hydrogen sulfite", "[SO2(OH)](-)", "bisulfite", "bisulphite", "hydrogen sulfite(1-)", "hydrosulfite anion" ; oboInOwl:id "CHEBI:17137" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogensulfite" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33482, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17359 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_48854 ] . obo:CHEBI_171664 obo:IAO_0000115 "An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amebicide", "amebicides", "amoebicide", "amoebicides", "anti-amoebic agent", "anti-amoebic agents", "anti-amoebic drug", "anti-amoebic drugs", "antiamoebic", "antiamoebic agents", "antiamoebic drug", "antiamoebic drugs", "antiamoebics" ; oboInOwl:id "CHEBI:171664" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antiamoebic agent" ; rdfs:subClassOf obo:CHEBI_35442 . obo:CHEBI_17258 obo:IAO_0000115 "The 7H-tautomer of purine." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" ; chebi:inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" ; chebi:mass "120.11222" ; chebi:monoisotopicmass "120.04360" ; chebi:smiles "c1ncc2[nH]cnc2n1" ; oboInOwl:hasAlternativeId "CHEBI:14968", "CHEBI:8639" ; oboInOwl:hasDbXref "Beilstein:3200", "Gmelin:601779", "HMDB:HMDB0001366", "KEGG:C15587", "Reaxys:3200" ; oboInOwl:hasExactSynonym "7H-purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Purine", "Purine base" ; oboInOwl:id "CHEBI:17258" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "7H-purine" ; rdfs:subClassOf obo:CHEBI_35584, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35586 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35588 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_173084 obo:IAO_0000115 "Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms." ; oboInOwl:hasDbXref "PMID:32015325", "PMID:32256352", "PMID:32413317", "PMID:33495651", "Wikipedia:Ferroptosis" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ferroptosis inhibitors" ; oboInOwl:id "CHEBI:173084" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ferroptosis inhibitor" ; rdfs:subClassOf obo:CHEBI_35222, obo:CHEBI_52206 . obo:CHEBI_17326 chebi:charge "0" ; chebi:formula "C5H12O13P3R" ; chebi:mass "373.063" ; chebi:monoisotopicmass "372.94908" ; chebi:smiles "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)(O)O)(=O)O)(=O)O" ; oboInOwl:hasAlternativeId "CHEBI:13411", "CHEBI:14677", "CHEBI:25610", "CHEBI:7442", "CHEBI:7655" ; oboInOwl:hasDbXref "KEGG:C00201" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NTP", "Nucleoside triphosphate", "nucleoside triphosphates" ; oboInOwl:id "CHEBI:17326" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-triphoshate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25608, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58104 ] . obo:CHEBI_17359 obo:IAO_0000115 "A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3)." ; chebi:charge "-2" ; chebi:formula "O3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)/p-2" ; chebi:inchikey "LSNNMFCWUKXFEE-UHFFFAOYSA-L" ; chebi:mass "80.06420" ; chebi:monoisotopicmass "79.95791" ; chebi:smiles "[O-]S([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:15139", "CHEBI:45548" ; oboInOwl:hasDbXref "CAS:14265-45-3", "Gmelin:1449", "PDBeChem:SO3" ; oboInOwl:hasExactSynonym "sulfite", "trioxidosulfate(2-)", "trioxosulfate(2-)", "trioxosulfate(IV)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SO3", "SO3(2-)", "SULFITE ION", "[SO3](2-)", "sulphite" ; oboInOwl:id "CHEBI:17359" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfite" ; rdfs:subClassOf obo:CHEBI_33482, obo:CHEBI_48154, obo:CHEBI_79388, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17137 ] . obo:CHEBI_17478 obo:IAO_0000115 "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group." ; chebi:charge "0" ; chebi:formula "CHOR" ; chebi:mass "29.01800" ; chebi:monoisotopicmass "29.00274" ; chebi:smiles "[H]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13432", "CHEBI:13753", "CHEBI:13805", "CHEBI:13806", "CHEBI:22291", "CHEBI:2554", "CHEBI:8750" ; oboInOwl:hasDbXref "KEGG:C00071" ; oboInOwl:hasExactSynonym "Aldehyde", "aldehyde", "aldehydes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aldehyd", "RC(=O)H", "RCHO", "aldehido", "aldehidos", "aldehydes", "aldehydum", "an aldehyde" ; oboInOwl:id "CHEBI:17478" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aldehyde" ; rdfs:subClassOf obo:CHEBI_36586, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_42485 ] . obo:CHEBI_17489 obo:IAO_0000115 "A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase." ; chebi:charge "0" ; chebi:formula "C10H12N5O6P" ; chebi:inchi "InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "IVOMOUWHDPKRLL-KQYNXXCUSA-N" ; chebi:mass "329.20614" ; chebi:monoisotopicmass "329.05252" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:11673", "CHEBI:1325", "CHEBI:19827", "CHEBI:41588" ; oboInOwl:hasDbXref "Beilstein:52645", "CAS:60-92-4", "DrugBank:DB02527", "HMDB:HMDB0000058", "KEGG:C00575", "KNApSAcK:C00001497", "MetaCyc:CAMP", "PDBeChem:CMP", "PMID:16295522", "PMID:18372334", "PMID:22770225", "Reaxys:52645", "Wikipedia:Cyclic_AMP" ; oboInOwl:hasExactSynonym "3',5'-Cyclic AMP", "adenosine 3',5'-(hydrogen phosphate)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE", "Adenosine 3',5'-cyclic phosphate", "Adenosine 3',5'-phosphate", "Cyclic AMP", "Cyclic adenylic acid", "adenosine 3',5'-cyclic monophosphate", "cAMP" ; oboInOwl:id "CHEBI:17489" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "3',5'-cyclic AMP" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_19834, obo:CHEBI_61296, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58165 ] . obo:CHEBI_17522 obo:IAO_0000115 "A carbohydrate that is an acyclic polyol having the general formula HOCH2[CH(OH)]nCH2OH (formally derivable from an aldose by reduction of the carbonyl group)." ; chebi:charge "0" ; chebi:formula "(CH2O)nC2H6O2" ; oboInOwl:hasAlternativeId "CHEBI:13754", "CHEBI:22298", "CHEBI:2556" ; oboInOwl:hasDbXref "KEGG:C00717", "Wikipedia:Glycerin" ; oboInOwl:hasExactSynonym "Alditol", "alditol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Glycitol", "Sugar alcohol", "alditols" ; oboInOwl:id "CHEBI:17522" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alditol" ; rdfs:subClassOf obo:CHEBI_16646, obo:CHEBI_26191 . obo:CHEBI_17544 obo:IAO_0000115 "The carbon oxoanion resulting from the removal of a proton from carbonic acid." ; chebi:charge "-1" ; chebi:formula "CHO3" ; chebi:inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1" ; chebi:inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-M" ; chebi:mass "61.01684" ; chebi:monoisotopicmass "60.99312" ; chebi:smiles "OC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:13363", "CHEBI:22863", "CHEBI:40961", "CHEBI:5589" ; oboInOwl:hasDbXref "Beilstein:3903504", "CAS:71-52-3", "Gmelin:49249", "HMDB:HMDB0000595", "KEGG:C00288", "MetaCyc:HCO3", "PDBeChem:BCT", "PMID:17215880", "PMID:17505962", "PMID:18439416", "PMID:28732801", "PMID:29150416", "PMID:29460248", "PMID:29466234", "PMID:4208463", "Wikipedia:Bicarbonate" ; oboInOwl:hasExactSynonym "Hydrogencarbonate", "hydrogen(trioxidocarbonate)(1-)", "hydrogencarbonate", "hydrogencarbonate(1-)", "hydrogentrioxocarbonate(1-)", "hydrogentrioxocarbonate(IV)", "hydroxidodioxidocarbonate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Acid carbonate", "BICARBONATE ION", "Bicarbonate", "HCO3(-)", "HCO3-", "[CO2(OH)](-)", "hydrogen carbonate" ; oboInOwl:id "CHEBI:17544" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogencarbonate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35604, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_41609 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_28976 ] . obo:CHEBI_17561 obo:IAO_0000115 "An optically active form of cysteine having L-configuration." ; chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-N" ; chebi:mass "121.15800" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "N[C@@H](CS)C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:13095", "CHEBI:21261", "CHEBI:41227", "CHEBI:41700", "CHEBI:41768", "CHEBI:41781", "CHEBI:41811", "CHEBI:6207" ; oboInOwl:hasDbXref "Beilstein:1721408", "CAS:52-90-4", "DrugBank:DB00151", "Drug_Central:769", "ECMDB:ECMDB00574", "Gmelin:49991", "HMDB:HMDB0000574", "KEGG:C00097", "KEGG:D00026", "KNApSAcK:C00001351", "MetaCyc:CYS", "PDBeChem:CYS", "PMID:11732994", "PMID:13761469", "PMID:22735334", "Reaxys:1721408", "Wikipedia:Cysteine", "YMDB:YMDB00046" ; oboInOwl:hasExactSynonym "L-Cysteine", "L-cysteine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R)-2-amino-3-mercaptopropanoic acid", "(2R)-2-amino-3-sulfanylpropanoic acid", "(R)-2-amino-3-mercaptopropanoic acid", "C", "CYSTEINE", "Cys", "E 920", "E-920", "E920", "FREE CYSTEINE", "L-2-Amino-3-mercaptopropionic acid", "L-Cystein", "L-Zystein" ; oboInOwl:id "CHEBI:17561" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-cysteine" ; rdfs:subClassOf obo:CHEBI_15356, obo:CHEBI_26650, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64577 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32442 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32445 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_16375 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35235 ] . obo:CHEBI_17568 obo:IAO_0000115 "A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription." ; chebi:charge "0" ; chebi:formula "C4H4N2O2" ; chebi:inchi "InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)" ; chebi:inchikey "ISAKRJDGNUQOIC-UHFFFAOYSA-N" ; chebi:mass "112.08684" ; chebi:monoisotopicmass "112.02728" ; chebi:smiles "O=c1cc[nH]c(=O)[nH]1" ; oboInOwl:hasAlternativeId "CHEBI:15288", "CHEBI:27210", "CHEBI:46375", "CHEBI:9882" ; oboInOwl:hasDbXref "Beilstein:606623", "CAS:66-22-8", "DrugBank:DB03419", "Gmelin:2896", "HMDB:HMDB0000300", "KEGG:C00106", "KEGG:D00027", "KNApSAcK:C00001513", "MetaCyc:URACIL", "PDBeChem:URA", "PMID:11279060", "PMID:12855717", "PMID:15274295", "PMID:16834123", "PMID:17439666", "PMID:18533995", "PMID:18815805", "PMID:19175333", "PMID:22020693", "PMID:22074393", "PMID:22120518", "PMID:22171528", "PMID:22237209", "PMID:22299724", "PMID:22356544", "PMID:22447672", "PMID:22483865", "PMID:22567906", "PMID:22685418", "PMID:3654008", "Reaxys:606623", "Wikipedia:Uracil" ; oboInOwl:hasExactSynonym "URACIL", "Uracil", "pyrimidine-2,4(1H,3H)-dione", "uracil" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,4(1H,3H)-pyrimidinedione", "2,4-Dioxopyrimidine", "2,4-Pyrimidinedione", "U", "Ura", "Urazil" ; oboInOwl:id "CHEBI:17568" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "uracil" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_26432, obo:CHEBI_38337, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50266 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50904 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_43254 ] . obo:CHEBI_17590 obo:IAO_0000115 "A straight chain alkane composed of 8 carbon atoms." ; chebi:charge "0" ; chebi:formula "C8H18" ; chebi:inchi "InChI=1S/C8H18/c1-3-5-7-8-6-4-2/h3-8H2,1-2H3" ; chebi:inchikey "TVMXDCGIABBOFY-UHFFFAOYSA-N" ; chebi:mass "114.22852" ; chebi:monoisotopicmass "114.14085" ; chebi:smiles "CCCCCCCC" ; oboInOwl:hasAlternativeId "CHEBI:14680", "CHEBI:25465", "CHEBI:25645", "CHEBI:44621", "CHEBI:7723" ; oboInOwl:hasDbXref "Beilstein:1696875", "CAS:111-65-9", "DrugBank:DB02440", "Gmelin:82412", "HMDB:HMDB0001485", "KEGG:C01387", "LIPID_MAPS_instance:LMFA11000002", "MetaCyc:CPD-148", "PDBeChem:OCT", "PMID:11255151", "PMID:24354334", "Reaxys:1696875", "UM-BBD_compID:c0044", "Wikipedia:Octane" ; oboInOwl:hasExactSynonym "Octane", "octane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3-[CH2]6-CH3", "N-OCTANE", "Oktan", "n-Octane", "n-Oktan" ; oboInOwl:id "CHEBI:17590" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "octane" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_18310, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ] . obo:CHEBI_176497 obo:IAO_0000115 "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan." ; oboInOwl:hasDbXref "PMID:23372317", "PMID:28580190", "PMID:30885572", "PMID:33144142", "PMID:33973253", "PMID:34606237", "Wikipedia:Geroprotector" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-aging agent", "anti-aging agents", "anti-aging drug", "anti-aging drugs", "geroprotective agent", "geroprotective agents", "geroprotectors" ; oboInOwl:id "CHEBI:176497" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "geroprotector" ; rdfs:subClassOf obo:CHEBI_50267 . obo:CHEBI_17688 obo:IAO_0000115 "A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum." ; chebi:charge "0" ; chebi:formula "C10H14N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1" ; chebi:inchikey "SNICXCGAKADSCV-JTQLQIEISA-N" ; chebi:mass "162.236" ; chebi:monoisotopicmass "162.11570" ; chebi:smiles "[H][C@]1(CCCN1C)C1=CC=CN=C1" ; oboInOwl:hasAlternativeId "CHEBI:14653", "CHEBI:25536", "CHEBI:44268", "CHEBI:7562" ; oboInOwl:hasDbXref "BPDB:485", "Beilstein:3604351", "Beilstein:82109", "CAS:54-11-5", "DrugBank:DB00184", "Drug_Central:1920", "HMDB:HMDB0001934", "KEGG:C00745", "KEGG:D03365", "KNApSAcK:C00002057", "LINCS:LSM-2093", "MetaCyc:NICOTINE", "PDBeChem:NCT", "PMID:11209966", "PMID:11322615", "PMID:11406005", "PMID:11719700", "PMID:11768184", "PMID:11821649", "PMID:11851194", "PMID:12575980", "PMID:12692774", "PMID:12769614", "PMID:12850578", "PMID:12971663", "PMID:13590907", "PMID:14674846", "PMID:14761239", "PMID:14975706", "PMID:15019421", "PMID:15027713", "PMID:15251917", "PMID:15276225", "PMID:15380834", "PMID:15502843", "PMID:15527885", "PMID:15707677", "PMID:15734728", "PMID:15826609", "PMID:15894687", "PMID:15902919", "PMID:15960296", "PMID:15963341", "PMID:16059663", "PMID:16212709", "PMID:16333621", "PMID:16370520", "PMID:16496293", "PMID:17023324", "PMID:17206646", "PMID:17292347", "PMID:17350101", "PMID:17498763", "PMID:17504235", "PMID:17525204", "PMID:17560039", "PMID:17683794", "PMID:18380035", "PMID:18383130", "PMID:18490768", "PMID:18683238", "PMID:18685152", "PMID:18805442", "PMID:18922921", "PMID:19100291", "PMID:19100331", "PMID:19287496", "PMID:19389046", "PMID:19448649", "PMID:19465085", "PMID:19850423", "PMID:19954906", "PMID:21521420", "PMID:21636612", "PMID:21822688", "PMID:21945235", "PMID:21947355", "PMID:22030716", "PMID:22129149", "PMID:22218403", "PMID:22265518", "PMID:22331007", "PMID:22377934", "PMID:22459798", "PMID:22529223", "PMID:22530136", "PMID:27951416", "PMID:28187919", "PMID:28391535", "PMID:28574230", "PMID:28641297", "PMID:28678400", "PMID:28683421", "PMID:28686840", "PMID:28698187", "PMID:28700952", "PMID:28704277", "PMID:28710519", "PMID:28711472", "PMID:28714396", "PMID:28718768", "PMID:28718828", "PMID:28726253", "PMID:28735272", "Reaxys:82109", "Wikipedia:Nicotine" ; oboInOwl:hasExactSynonym "(S)-Nicotine", "(S)-nicotine", "3-[(2S)-1-methylpyrrolidin-2-yl]pyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-3-(1-Methyl-2-pyrrolidyl)pyridine", "(-)-3-(N-Methylpyrrolidino)pyridine", "(-)-nicotine", "(R)-3-(1-Methyl-2-pyrrolidinyl)pyridine", "(S)-(-)-nicotine", "(S)-3-(1-methylpyrrolidin-2-yl)pyridine", "(S)-3-(N-methylpyrrolidin-2-yl)pyridine", "1-Methyl-2-(3-pyridyl)pyrrolidine", "3-(1-Methyl-2-pyrollidinyl)pyridine", "3-(1-Methylpyrrolidin-2-yl)pyridine", "3-(2-(N-methylpyrrolidinyl))pyridine", "3-(N-methylpyrollidino)pyridine", "L(-)-nicotine", "L-3-(1-Methyl-2-pyrrolidyl)pyridine", "L-Nicotine", "Nicotine" ; oboInOwl:id "CHEBI:17688" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(S)-nicotine" ; rdfs:subClassOf obo:CHEBI_138000, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22917 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35474 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_47958 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_49110 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50846 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_52290 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59163 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_59806 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_39162 ] . obo:CHEBI_17754 obo:IAO_0000115 "A triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups." ; chebi:charge "0" ; chebi:formula "C3H8O3" ; chebi:inchi "InChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2" ; chebi:inchikey "PEDCQBHIVMGVHV-UHFFFAOYSA-N" ; chebi:mass "92.09382" ; chebi:monoisotopicmass "92.04734" ; chebi:smiles "OCC(O)CO" ; oboInOwl:hasAlternativeId "CHEBI:131422", "CHEBI:14334", "CHEBI:24351", "CHEBI:42998", "CHEBI:5448" ; oboInOwl:hasDbXref "Beilstein:635685", "CAS:56-81-5", "Chemspider:733", "DrugBank:DB04077", "Drug_Central:1316", "ECMDB:ECMDB00131", "FooDB:FDB000756", "Gmelin:26279", "HMDB:HMDB0000131", "KEGG:C00116", "KEGG:D00028", "KNApSAcK:C00001163", "LINCS:LSM-37180", "MetaCyc:GLYCEROL", "PDB:2AJS", "PDB:2D03", "PDBeChem:GOL", "PMID:11302662", "PMID:11958517", "PMID:11994365", "PMID:12672239", "PMID:12687625", "PMID:12689633", "PMID:12713573", "PMID:14559393", "PMID:14563847", "PMID:15026783", "PMID:15342117", "PMID:15786693", "PMID:15983192", "PMID:16244855", "PMID:16258193", "PMID:16319039", "PMID:16349488", "PMID:16475911", "PMID:16651733", "PMID:16664750", "PMID:16901854", "PMID:17336832", "PMID:17439666", "PMID:17979222", "PMID:19184438", "PMID:19231894", "PMID:19460032", "PMID:19548674", "PMID:19795216", "PMID:19956799", "PMID:22705534", "PMID:23562176", "PMID:23747440", "PMID:24643482", "PMID:24835191", "PMID:25108762", "PMID:558160", "PMID:6299616", "PMID:7031247", "PMID:7392035", "PPDB:1317", "Reaxys:635685", "UM-BBD_compID:c0066", "Wikipedia:Glycerol", "YMDB:YMDB00283" ; oboInOwl:hasExactSynonym "GLYCEROL", "Glycerol", "glycerol", "propane-1,2,3-triol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2,3-Propanetriol", "1,2,3-Trihydroxypropane", "Glycerin", "Glyceritol", "Glyzerin", "Gro", "Oelsuess", "Propanetriol", "Trihydroxypropane", "glycerine", "glycerol", "glycerolum", "glycyl alcohol" ; oboInOwl:id "CHEBI:17754" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glycerol" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_17522, obo:CHEBI_27136, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25728 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27780 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84735 ] . obo:CHEBI_17790 obo:IAO_0000115 "The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group." ; chebi:charge "0" ; chebi:formula "CH4O" ; chebi:inchi "InChI=1S/CH4O/c1-2/h2H,1H3" ; chebi:inchikey "OKKJLVBELUTLKV-UHFFFAOYSA-N" ; chebi:mass "32.04186" ; chebi:monoisotopicmass "32.02621" ; chebi:smiles "CO" ; oboInOwl:hasAlternativeId "CHEBI:14588", "CHEBI:25227", "CHEBI:44080", "CHEBI:44553", "CHEBI:6816" ; oboInOwl:hasDbXref "Beilstein:1098229", "CAS:67-56-1", "Gmelin:449", "HMDB:HMDB0001875", "KEGG:C00132", "KEGG:D02309", "MetaCyc:METOH", "PDBeChem:MOH", "PMID:11141607", "PMID:11430978", "PMID:11489599", "PMID:11680737", "PMID:11684179", "PMID:14012711", "PMID:14678513", "PMID:14760634", "PMID:15172721", "PMID:15906011", "PMID:16705261", "PMID:17451998", "PMID:17733096", "PMID:19064074", "PMID:19850112", "PMID:20314698", "Reaxys:1098229", "UM-BBD_compID:c0132", "Wikipedia:Methanol" ; oboInOwl:hasExactSynonym "METHANOL", "Methanol", "methanol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3OH", "MeOH", "Methyl alcohol", "Methylalkohol", "carbinol", "spirit of wood", "wood alcohol", "wood naphtha", "wood spirit" ; oboInOwl:id "CHEBI:17790" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methanol" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_134179, obo:CHEBI_15734, obo:CHEBI_50584, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_131604 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33292 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48360 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_52090 ] . obo:CHEBI_17792 obo:IAO_0000115 "A compound containing at least one carbon-halogen bond (where X is a halogen atom)." ; chebi:charge "0" ; chebi:formula "RX" ; chebi:smiles "**" ; oboInOwl:hasAlternativeId "CHEBI:13444", "CHEBI:36684", "CHEBI:8767" ; oboInOwl:hasDbXref "KEGG:C01322", "MetaCyc:Organohalogen-Compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RX", "organic halide", "organic halides", "organohalogen compounds" ; oboInOwl:id "CHEBI:17792" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organohalogen compound" ; rdfs:subClassOf obo:CHEBI_33285, obo:CHEBI_37578 . obo:CHEBI_17883 obo:IAO_0000115 "A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms." ; chebi:charge "0" ; chebi:formula "ClH", "HCl" ; chebi:inchi "InChI=1S/ClH/h1H" ; chebi:inchikey "VEXZGXHMUGYJMC-UHFFFAOYSA-N" ; chebi:mass "36.46064" ; chebi:monoisotopicmass "35.97668" ; chebi:smiles "Cl[H]" ; oboInOwl:hasAlternativeId "CHEBI:13364", "CHEBI:24635", "CHEBI:5590" ; oboInOwl:hasDbXref "CAS:7647-01-0", "Drug_Central:4568", "Gmelin:322", "HMDB:HMDB0002306", "KEGG:C01327", "KEGG:D02057", "MetaCyc:HCL", "PMID:15823700", "PMID:17492841", "PMID:22804993", "Reaxys:1098214", "Wikipedia:HCl", "Wikipedia:Hydrochloric_acid" ; oboInOwl:hasExactSynonym "Hydrogen chloride", "chlorane", "chloridohydrogen", "hydrogen chloride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Chlorwasserstoff", "HCl", "Hydrochloride", "Hydrogenchlorid", "Wasserstoffchlorid", "[HCl]", "chlorure d'hydrogene", "cloruro de hidrogeno", "hydrochloric acid" ; oboInOwl:id "CHEBI:17883" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogen chloride" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_18140, obo:CHEBI_23117, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17996 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_50315 ] . obo:CHEBI_17891 obo:IAO_0000115 "A molecular entity that can transfer (\"donate\") an electron, a pair of electrons, an atom or a group to another molecular entity." ; oboInOwl:hasAlternativeId "CHEBI:14202", "CHEBI:4697" ; oboInOwl:hasDbXref "KEGG:C01351" ; oboInOwl:hasExactSynonym "Donor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Donator", "donneur" ; oboInOwl:id "CHEBI:17891" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "donor" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_17968 obo:IAO_0000115 "A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group." ; chebi:charge "-1" ; chebi:formula "C4H7O2" ; chebi:inchi "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)/p-1" ; chebi:inchikey "FERIUCNNQQJTOY-UHFFFAOYSA-M" ; chebi:mass "87.09718" ; chebi:monoisotopicmass "87.04515" ; chebi:smiles "CCCC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:13924", "CHEBI:22946" ; oboInOwl:hasDbXref "Beilstein:3601060", "CAS:461-55-2", "Gmelin:324289", "KEGG:C00246", "MetaCyc:BUTYRIC_ACID", "PMID:17190852", "PMID:7496326", "Reaxys:3601060", "UM-BBD_compID:c0035" ; oboInOwl:hasExactSynonym "butanoate", "butyrate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-butanoate", "1-butyrate", "1-propanecarboxylate", "CH3-[CH2]2-COO(-)", "butanate", "butanoate", "butanoic acid, ion(1-)", "n-butanoate", "n-butyrate", "propanecarboxylate", "propylformate" ; oboInOwl:id "CHEBI:17968" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "butyrate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_78115, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_61115 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_30772 ] . obo:CHEBI_17972 chebi:charge "0" ; chebi:formula "C5H12O13P3R" ; chebi:mass "373.063" ; chebi:monoisotopicmass "372.94908" ; oboInOwl:hasAlternativeId "CHEBI:15047", "CHEBI:26559", "CHEBI:8846" ; oboInOwl:hasDbXref "KEGG:C03802" ; oboInOwl:hasExactSynonym "Ribonucleoside triphosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleoside triphosphates" ; oboInOwl:id "CHEBI:17972" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribonucleoside triphosphate" ; rdfs:subClassOf obo:CHEBI_17326 . obo:CHEBI_17996 obo:IAO_0000115 "A halide anion formed when chlorine picks up an electron to form an an anion." ; chebi:charge "-1" ; chebi:formula "Cl" ; chebi:inchi "InChI=1S/ClH/h1H/p-1" ; chebi:inchikey "VEXZGXHMUGYJMC-UHFFFAOYSA-M" ; chebi:mass "35.45270" ; chebi:monoisotopicmass "34.96940" ; chebi:smiles "[Cl-]" ; oboInOwl:hasAlternativeId "CHEBI:13291", "CHEBI:13970", "CHEBI:3616", "CHEBI:3731", "CHEBI:48804" ; oboInOwl:hasDbXref "Beilstein:3587171", "CAS:16887-00-6", "Gmelin:14910", "KEGG:C00115", "KEGG:C00698", "PDBeChem:CL", "UM-BBD_compID:c0884" ; oboInOwl:hasExactSynonym "Chloride", "chloride", "chloride(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CHLORIDE ION", "Chloride ion", "Chloride(1-)", "Chlorine anion", "Cl(-)", "Cl-" ; oboInOwl:id "CHEBI:17996" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chloride" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_16042, obo:CHEBI_33432, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17883 ] . obo:CHEBI_18059 obo:IAO_0000115 "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids." ; oboInOwl:hasAlternativeId "CHEBI:14517", "CHEBI:25054", "CHEBI:6486" ; oboInOwl:hasDbXref "KEGG:C01356" ; oboInOwl:hasExactSynonym "Lipid", "lipids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:18059" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "lipid" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_18099 obo:IAO_0000115 "An alcohol that consists of cyclohexane bearing a single hydroxy substituent. The parent of the class of cyclohexanols." ; chebi:charge "0" ; chebi:formula "C6H12O" ; chebi:inchi "InChI=1S/C6H12O/c7-6-4-2-1-3-5-6/h6-7H,1-5H2" ; chebi:inchikey "HPXRVTGHNJAIIH-UHFFFAOYSA-N" ; chebi:mass "100.15888" ; chebi:monoisotopicmass "100.08882" ; chebi:smiles "OC1CCCCC1" ; oboInOwl:hasAlternativeId "CHEBI:14051", "CHEBI:23471", "CHEBI:4013", "CHEBI:41739" ; oboInOwl:hasDbXref "CAS:108-93-0", "DrugBank:DB03703", "KEGG:C00854", "MetaCyc:CYCLOHEXANOL", "PDBeChem:CXL", "PMID:11682644", "PMID:23825601", "Reaxys:906744", "UM-BBD_compID:c0175", "Wikipedia:Cyclohexanol" ; oboInOwl:hasExactSynonym "Cyclohexanol", "cyclohexanol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-Cyclohexanol", "Cyclohexan-1-ol", "Cyclohexyl alcohol", "Hexahydrophenol", "Hexalin", "Hydrophenol", "Hydroxycyclohexane" ; oboInOwl:id "CHEBI:18099" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclohexanol" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_23480, obo:CHEBI_35681, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ] . obo:CHEBI_18133 obo:IAO_0000115 "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose)." ; oboInOwl:hasAlternativeId "CHEBI:14399", "CHEBI:24590", "CHEBI:5709" ; oboInOwl:hasDbXref "GlyGen:G70994MS", "GlyTouCan:G70994MS", "KEGG:C00738" ; oboInOwl:hasExactSynonym "Hexose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/", "hexoses" ; oboInOwl:id "CHEBI:18133" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hexose" ; rdfs:subClassOf obo:CHEBI_35381 . obo:CHEBI_18140 chebi:charge "0" ; chebi:formula "HX" ; chebi:mass "1.008" ; chebi:monoisotopicmass "1.00783" ; chebi:smiles "*[H]" ; oboInOwl:hasAlternativeId "CHEBI:13368", "CHEBI:37140", "CHEBI:5599" ; oboInOwl:hasExactSynonym "hydrogen halide", "hydrogen halides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydrogen halides" ; oboInOwl:id "CHEBI:18140" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogen halide" ; rdfs:subClassOf obo:CHEBI_33405, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138103 ] . obo:CHEBI_18154 obo:IAO_0000115 "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues." ; oboInOwl:hasAlternativeId "CHEBI:14864", "CHEBI:26205", "CHEBI:8322" ; oboInOwl:hasDbXref "KEGG:C00420" ; oboInOwl:hasExactSynonym "Polysaccharide", "polysaccharides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Glycan", "Glycane", "Glykan", "Glykane", "glycans", "polisacarido", "polisacaridos" ; oboInOwl:id "CHEBI:18154" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polysaccharide" ; rdfs:subClassOf obo:CHEBI_16646, obo:CHEBI_167559, obo:CHEBI_33694 . obo:CHEBI_18179 obo:IAO_0000115 "Any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol." ; oboInOwl:hasAlternativeId "CHEBI:14806", "CHEBI:60751", "CHEBI:8132" ; oboInOwl:hasDbXref "PMID:10782093", "PMID:15269334", "PMID:17035995", "PMID:19154715" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:18179" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphoinositide" ; rdfs:subClassOf obo:CHEBI_28874 . obo:CHEBI_18243 obo:IAO_0000115 "Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group." ; chebi:charge "0" ; chebi:formula "C8H11NO2" ; chebi:inchi "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2" ; chebi:inchikey "VYFYYTLLBUKUHU-UHFFFAOYSA-N" ; chebi:mass "153.17840" ; chebi:monoisotopicmass "153.07898" ; chebi:smiles "NCCc1ccc(O)c(O)c1" ; oboInOwl:hasAlternativeId "CHEBI:11695", "CHEBI:11930", "CHEBI:14203", "CHEBI:1764", "CHEBI:23886", "CHEBI:43686" ; oboInOwl:hasDbXref "CAS:51-61-6", "DrugBank:DB00988", "Drug_Central:947", "HMDB:HMDB0000073", "KEGG:C03758", "KEGG:D07870", "KNApSAcK:C00001408", "LINCS:LSM-4630", "MetaCyc:DOPAMINE", "PMID:10629745", "PMID:11149432", "PMID:9422813", "Reaxys:1072822", "Wikipedia:Dopamine" ; oboInOwl:hasExactSynonym "4-(2-aminoethyl)benzene-1,2-diol", "Dopamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-(3,4-Dihydroxyphenyl)ethylamine", "2-(3,4-dihydroxyphenyl)ethylamine", "3,4-Dihydroxyphenethylamine", "3-Hydroxytyramine", "4-(2-Aminoethyl)-1,2-benzenediol", "4-(2-Aminoethyl)benzene-1,2-diol", "4-(2-aminoethyl)-1,2-benzenediol", "4-(2-aminoethyl)catechol", "4-(2-aminoethyl)pyrocatechol", "Deoxyepinephrine", "Hydroxytyramin", "dopamina", "dopamine", "dopaminum" ; oboInOwl:id "CHEBI:18243" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dopamine" ; rdfs:subClassOf obo:CHEBI_33567, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35522 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35524 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38147 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48560 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_59905 ] . obo:CHEBI_18248 obo:IAO_0000115 "An iron group element atom that has atomic number 26." ; chebi:charge "0" ; chebi:formula "Fe" ; chebi:inchi "InChI=1S/Fe" ; chebi:inchikey "XEEYBQQBJWHFJM-UHFFFAOYSA-N" ; chebi:mass "55.84500" ; chebi:monoisotopicmass "55.93494" ; chebi:smiles "[Fe]" ; oboInOwl:hasAlternativeId "CHEBI:13322", "CHEBI:24872", "CHEBI:5974" ; oboInOwl:hasDbXref "CAS:7439-89-6", "DrugBank:DB01592", "HMDB:HMDB0015531", "KEGG:C00023", "Reaxys:4122945", "WebElements:Fe" ; oboInOwl:hasExactSynonym "iron" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "26Fe", "Eisen", "Fe", "Iron", "fer", "ferrum", "hierro", "iron" ; oboInOwl:id "CHEBI:18248" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iron atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33356, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_18254 obo:IAO_0000115 "Any nucleoside where the sugar component is D-ribose." ; chebi:charge "0" ; chebi:formula "C5H9O4R" ; chebi:mass "133.123" ; chebi:monoisotopicmass "133.05008" ; chebi:smiles "OC[C@H]1O[C@@H]([*])[C@H](O)[C@@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:13014", "CHEBI:13015", "CHEBI:13685", "CHEBI:21085", "CHEBI:26560", "CHEBI:4240", "CHEBI:8844" ; oboInOwl:hasDbXref "KEGG:C00911" ; oboInOwl:hasExactSynonym "Ribonucleoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a ribonucleoside", "ribonucleosides" ; oboInOwl:id "CHEBI:18254" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribonucleoside" ; rdfs:subClassOf obo:CHEBI_33838, obo:CHEBI_47019 . obo:CHEBI_18282 obo:IAO_0000115 "That part of DNA or RNA that may be involved in pairing." ; oboInOwl:hasAlternativeId "CHEBI:13873", "CHEBI:25598", "CHEBI:2995" ; oboInOwl:hasDbXref "KEGG:C00701", "Wikipedia:Nucleobase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Base", "nucleobases" ; oboInOwl:id "CHEBI:18282" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleobase" ; rdfs:subClassOf obo:CHEBI_38101 . obo:CHEBI_18291 chebi:charge "0" ; chebi:formula "Mn" ; chebi:inchi "InChI=1S/Mn" ; chebi:inchikey "PWHULOQIROXLJO-UHFFFAOYSA-N" ; chebi:mass "54.93805" ; chebi:monoisotopicmass "54.93804" ; chebi:smiles "[Mn]" ; oboInOwl:hasAlternativeId "CHEBI:13382", "CHEBI:25153", "CHEBI:6681" ; oboInOwl:hasDbXref "CAS:7439-96-5", "KEGG:C00034", "WebElements:Mn" ; oboInOwl:hasExactSynonym "manganese" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "25Mn", "Mangan", "Manganese", "Mn", "manganese", "manganeso", "manganum" ; oboInOwl:id "CHEBI:18291" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "manganese atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33352, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_18310 obo:IAO_0000115 "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms." ; chebi:charge "0" ; chebi:formula "CH3R" ; chebi:mass "15.035" ; chebi:monoisotopicmass "15.02348" ; chebi:smiles "C[*]" ; oboInOwl:hasAlternativeId "CHEBI:13435", "CHEBI:22317", "CHEBI:2576" ; oboInOwl:hasDbXref "KEGG:C01371" ; oboInOwl:hasExactSynonym "Alkane", "alkane", "alkanes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Alkan", "RH", "alcane", "alcanes", "alcano", "alcanos", "an alkane" ; oboInOwl:id "CHEBI:18310" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkane" ; rdfs:subClassOf obo:CHEBI_24632, obo:CHEBI_33653 . obo:CHEBI_18367 obo:IAO_0000115 "A phosphate ion that is the conjugate base of hydrogenphosphate." ; chebi:charge "-3" ; chebi:formula "O4P" ; chebi:inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3" ; chebi:inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-K" ; chebi:mass "94.97136" ; chebi:monoisotopicmass "94.95507" ; chebi:smiles "[O-]P([O-])([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:14791", "CHEBI:45024", "CHEBI:7793" ; oboInOwl:hasDbXref "Beilstein:3903772", "CAS:14265-44-2", "Gmelin:1997", "KEGG:C00009", "PDBeChem:PO4", "Reaxys:3903772" ; oboInOwl:hasExactSynonym "phosphate", "tetraoxidophosphate(3-)", "tetraoxophosphate(3-)", "tetraoxophosphate(V)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Orthophosphate", "PHOSPHATE ION", "PO4(3-)", "Phosphate", "[PO4](3-)" ; oboInOwl:id "CHEBI:18367" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphate(3-)" ; rdfs:subClassOf obo:CHEBI_35780, obo:CHEBI_79387, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_43474 ] . obo:CHEBI_18375 obo:IAO_0000115 "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-3 and C-5 of the ribose ring are engaged in formation of a cyclic mono-, di-, tri- or tetra-phosphate." ; chebi:charge "0" ; chebi:formula "C5H7O5PR2" ; chebi:mass "178.07980" ; chebi:monoisotopicmass "178.00311" ; chebi:smiles "OP1(=O)OC[C@H]2O[C@@H]([*])[C@H]([*])[C@@H]2O1" ; oboInOwl:hasAlternativeId "CHEBI:1331", "CHEBI:14672", "CHEBI:19833" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleoside 3',5'-cyclic phosphates" ; oboInOwl:id "CHEBI:18375" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside 3',5'-cyclic phosphate" ; rdfs:subClassOf obo:CHEBI_23447, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58464 ] . obo:CHEBI_18723 obo:IAO_0000115 "A racemate composed of equimolar amounts of (R)- and (S)-nicotine." ; oboInOwl:hasDbXref "Beilstein:82108", "Beilstein:82111", "CAS:22083-74-5", "DrugBank:DB00184", "HMDB:HMDB0014330", "KEGG:C16150", "KNApSAcK:C00002057", "PMID:10751565", "PMID:11192937", "PMID:11471991", "PMID:11559179", "PMID:11682702", "PMID:11714820", "PMID:11719700", "PMID:11801622", "PMID:11818389", "PMID:11860617", "PMID:12197757", "PMID:12700710", "PMID:12965231", "PMID:14715938", "PMID:15183514", "PMID:15251917", "PMID:15313135", "PMID:15458549", "PMID:15707677", "PMID:15894687", "PMID:15960296", "PMID:15961264", "PMID:16496293", "PMID:16950410", "PMID:17167832", "PMID:17206646", "PMID:17438652", "PMID:17498149", "PMID:17942810", "PMID:18077004", "PMID:18311975", "PMID:18380035", "PMID:18383130", "PMID:18651995", "PMID:18922921", "PMID:19100331", "PMID:19287496", "PMID:19389046", "PMID:19465085", "PMID:20338106", "PMID:20528766", "PMID:21636612", "PMID:21822688", "PMID:21945235", "PMID:22129149", "PMID:22218403", "PMID:22331007", "PMID:22377934", "PMID:22448647", "PMID:22459798", "PMID:22529223", "PMID:22573728", "PMID:22585541", "PMID:22589423", "PMID:22770225", "PMID:22792725", "PMID:22855884", "PMID:22930863", "PMID:22935730", "PMID:23108361", "PMID:23117126", "PMID:7097594", "PMID:7564279", "PMID:7566693", "PMID:7807214", "PMID:7896575", "PMID:8156919", "PMID:8545712", "PMID:8764340", "PMID:9203638", "PMID:9450943", "PMID:9621392", "Reaxys:82108", "UM-BBD_compID:c0468", "Wikipedia:Nicotine" ; oboInOwl:hasExactSynonym "rac-3-(1-methylpyrrolidin-2-yl)pyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine", "(+-)-nicotine", "(R,S)-nicotine", "(RS)-nicotine", "nicotin", "nikotin" ; oboInOwl:id "CHEBI:18723" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nicotine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_60911, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17688 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_39162 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35474 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_47958 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_49110 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50846 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50910 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_52290 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59163 ] . obo:CHEBI_19129 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "11alpha-hydroxy steroids" ; oboInOwl:id "CHEBI:19129" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "11alpha-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_36841 . obo:CHEBI_193111 obo:IAO_0000115 "The conjugate base of methylcarbamic acid; major microspecies at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C2H4NO2" ; chebi:inchi "InChI=1S/C2H5NO2/c1-3-2(4)5/h3H,1H3,(H,4,5)/p-1" ; chebi:inchikey "UFEJKYYYVXYMMS-UHFFFAOYSA-M" ; chebi:mass "74.060" ; chebi:monoisotopicmass "74.02475" ; chebi:smiles "CNC([O-])=O" ; oboInOwl:hasDbXref "MetaCyc:CPD-22706" ; oboInOwl:hasExactSynonym "methylcarbamate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-methyl carbamate", "N-methylcarbamate" ; oboInOwl:id "CHEBI:193111" ; oboInOwl:inSubset chebi2:_STAR ; a owl:Class ; rdfs:label "methylcarbamate" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_13941 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_45379 ] . obo:CHEBI_194338 obo:IAO_0000115 "Any agent that interferes with the activity of T-type calcium channels." ; oboInOwl:hasDbXref "PMID:30372652", "PMID:36738196", "Wikipedia:T-type_calcium_channel" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "T-type calcium channel antagonist", "T-type calcium channel antagonists", "T-type calcium channel blockers" ; oboInOwl:id "CHEBI:194338" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "T-type calcium channel blocker" ; rdfs:subClassOf obo:CHEBI_38215 . obo:CHEBI_197506 obo:IAO_0000115 "Any fatty alcohol with a chain length between C6 and C12." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "medium-chain fatty alcohols" ; oboInOwl:id "CHEBI:197506" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "medium-chain fatty alcohol" ; rdfs:subClassOf obo:CHEBI_24026 . obo:CHEBI_19834 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3',5'-cyclic purine nucleotides" ; oboInOwl:id "CHEBI:19834" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "3',5'-cyclic purine nucleotide" ; rdfs:subClassOf obo:CHEBI_18375, obo:CHEBI_36982 . obo:CHEBI_20702 obo:IAO_0000115 "Any aminopurine having the amino substituent at the 2-position." ; oboInOwl:hasExactSynonym "2-aminopurines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:20702" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "2-aminopurines" ; rdfs:subClassOf obo:CHEBI_22527 . obo:CHEBI_20706 obo:IAO_0000115 "Any compound having 6-aminopurine (adenine) as part of its structure." ; oboInOwl:hasDbXref "PMID:1646334", "PMID:18524423", "PMID:7342604" ; oboInOwl:hasExactSynonym "6-aminopurines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:20706" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "6-aminopurines" ; rdfs:subClassOf obo:CHEBI_22527 . obo:CHEBI_21731 obo:IAO_0000115 "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond." ; oboInOwl:hasExactSynonym "glycosylamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-glycoside", "N-glycosides", "N-glycosyl compounds", "glycosylamines" ; oboInOwl:id "CHEBI:21731" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "N-glycosyl compound" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_63161 . obo:CHEBI_22153 obo:IAO_0000115 "A substance used to destroy pests of the subclass Acari (mites and ticks)." ; oboInOwl:hasDbXref "Wikipedia:Acaricide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Akarizid", "Akarizide", "acaricides", "miticide" ; oboInOwl:id "CHEBI:22153" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acaricide" ; rdfs:subClassOf obo:CHEBI_25944 . obo:CHEBI_22160 obo:IAO_0000115 "Compounds with the general formula RNHC(=O)CH3." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22160" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acetamides" ; rdfs:subClassOf obo:CHEBI_37622 . obo:CHEBI_22221 obo:IAO_0000115 "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids." ; oboInOwl:hasExactSynonym "acyl group", "alkanoyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acyl groups", "alkanoyl group", "groupe acyle" ; oboInOwl:id "CHEBI:22221" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acyl group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_22256 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenosine phosphates" ; oboInOwl:id "CHEBI:22256" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adenosine phosphate" ; rdfs:subClassOf obo:CHEBI_61296, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16335 ] . obo:CHEBI_22260 obo:IAO_0000115 "Any purine ribonucleoside that is a derivative of adenosine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22260" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adenosines" ; rdfs:subClassOf obo:CHEBI_26399, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16708 ] . obo:CHEBI_22307 obo:IAO_0000115 "Oximes of aldehydes RCH=NOH." ; chebi:charge "0" ; chebi:formula "CH2NOR" ; chebi:mass "44.03270" ; chebi:monoisotopicmass "44.01364" ; chebi:smiles "[H]C([*])=NO" ; oboInOwl:hasDbXref "KEGG:C02658" ; oboInOwl:hasExactSynonym "aldoxime", "aldoximes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldoximes" ; oboInOwl:id "CHEBI:22307" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aldoxime" ; rdfs:subClassOf obo:CHEBI_25750 . obo:CHEBI_22313 oboInOwl:hasExactSynonym "alkaline earth metals" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Erdalkalimetall", "Erdalkalimetalle", "alkaline earth metal", "alkaline-earth metal", "alkaline-earth metals", "metal alcalino-terreux", "metal alcalinoterreo", "metales alcalinoterreos", "metaux alcalino-terreux" ; oboInOwl:id "CHEBI:22313" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkaline earth metal atom" ; rdfs:subClassOf obo:CHEBI_33318, obo:CHEBI_33521, obo:CHEBI_33559 . obo:CHEBI_22314 oboInOwl:hasExactSynonym "alkali metals" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Alkalimetall", "Alkalimetalle", "alkali metal", "metal alcalin", "metal alcalino", "metales alcalinos", "metaux alcalins" ; oboInOwl:id "CHEBI:22314" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkali metal atom" ; rdfs:subClassOf obo:CHEBI_33318, obo:CHEBI_33521, obo:CHEBI_33559 . obo:CHEBI_22315 obo:IAO_0000115 "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids." ; oboInOwl:hasDbXref "Wikipedia:Alkaloid" ; oboInOwl:hasExactSynonym "Alkaloid", "alkaloids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Alkaloide", "alcaloide", "alcaloides" ; oboInOwl:id "CHEBI:22315" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkaloid" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35352, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25212 ] . obo:CHEBI_22323 obo:IAO_0000115 "A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom." ; oboInOwl:hasExactSynonym "alkyl group", "alkyl groups" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "groupe alkyle", "grupo alquilo", "grupos alquilo" ; oboInOwl:id "CHEBI:22323" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkyl group" ; rdfs:subClassOf obo:CHEBI_33248, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_18310 ] . obo:CHEBI_22327 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aliphatic thioether", "aliphatic thioethers" ; oboInOwl:id "CHEBI:22327" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aliphatic sulfide" ; rdfs:subClassOf obo:CHEBI_16385 . obo:CHEBI_22333 obo:IAO_0000115 "Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22333" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkylating agent" ; rdfs:subClassOf obo:CHEBI_25435 . obo:CHEBI_22478 obo:IAO_0000115 "An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino alcohols", "aminoalcohol", "aminoalcohols" ; oboInOwl:id "CHEBI:22478" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amino alcohol" ; rdfs:subClassOf obo:CHEBI_30879, obo:CHEBI_50047 . obo:CHEBI_22527 obo:IAO_0000115 "Any purine having at least one amino substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aminopurines" ; oboInOwl:id "CHEBI:22527" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aminopurine" ; rdfs:subClassOf obo:CHEBI_26401 . obo:CHEBI_22562 obo:IAO_0000115 "Any aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22562" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anilines" ; rdfs:subClassOf obo:CHEBI_22712, obo:CHEBI_33860 . obo:CHEBI_22563 obo:IAO_0000115 "A monoatomic or polyatomic species having one or more elementary charges of the electron." ; oboInOwl:hasExactSynonym "Anion", "anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Anionen", "aniones", "anions" ; oboInOwl:id "CHEBI:22563" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anion" ; rdfs:subClassOf obo:CHEBI_24870 . obo:CHEBI_22586 obo:IAO_0000115 "A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antioxidants", "antioxydant", "antoxidant" ; oboInOwl:id "CHEBI:22586" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antioxidant" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_22587 obo:IAO_0000115 "A substance that destroys or inhibits replication of viruses." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-viral agent", "anti-viral agents", "antiviral", "antiviral agents", "antivirals" ; oboInOwl:id "CHEBI:22587" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antiviral agent" ; rdfs:subClassOf obo:CHEBI_33281 . obo:CHEBI_22632 oboInOwl:hasExactSynonym "arsenic molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "arsenic compounds", "arsenic molecular entities" ; oboInOwl:id "CHEBI:22632" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "arsenic molecular entity" ; rdfs:subClassOf obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_27563 ] . obo:CHEBI_22633 obo:IAO_0000115 "An arsenic oxoanion resulting from the removal of one or more protons from arsenous acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "arsenite anions", "arsenite ions" ; oboInOwl:id "CHEBI:22633" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "arsenite ion" ; rdfs:subClassOf obo:CHEBI_24834, obo:CHEBI_35776 . obo:CHEBI_22695 obo:IAO_0000115 "A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base)." ; oboInOwl:hasDbXref "KEGG:C00701" ; oboInOwl:hasExactSynonym "Base", "base" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Base1", "Base2", "Basen", "Nucleobase", "bases" ; oboInOwl:id "CHEBI:22695" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "base" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_22698 obo:IAO_0000115 "Any arenecarbaldehyde that consists of a formyl substituted benzene ring and its substituted derivatives thereof." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22698" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "benzaldehydes" ; rdfs:subClassOf obo:CHEBI_33855 . obo:CHEBI_22712 obo:IAO_0000115 "Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:22712" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "benzenes" ; rdfs:subClassOf obo:CHEBI_33836 . obo:CHEBI_22728 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "benzopyrroles" ; oboInOwl:id "CHEBI:22728" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "benzopyrrole" ; rdfs:subClassOf obo:CHEBI_27171, obo:CHEBI_38101, obo:CHEBI_38180 . obo:CHEBI_22901 obo:IAO_0000115 "By usage, the methylenediphenols, HOC6H4CH2C6H4OH, commonly p,p-methylenediphenol, and their substitution products (generally derived from condensation of two equivalent amounts of a phenol with an aldehyde or ketone). The term also includes analogues in the the methylene (or substituted methylene) group has been replaced by a heteroatom." ; oboInOwl:hasDbXref "Wikipedia:Bisphenol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bisphenols" ; oboInOwl:id "CHEBI:22901" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bisphenol" ; rdfs:subClassOf obo:CHEBI_33853 . obo:CHEBI_22917 obo:IAO_0000115 "An insecticide compound naturally occurring in plants." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "botanical insecticide", "botanical insecticides", "phytogenic insecticides" ; oboInOwl:id "CHEBI:22917" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phytogenic insecticide" ; rdfs:subClassOf obo:CHEBI_24852 . obo:CHEBI_22927 chebi:charge "0" ; chebi:formula "Br" ; chebi:inchi "InChI=1S/Br" ; chebi:inchikey "WKBOTKDWSSQWDR-UHFFFAOYSA-N" ; chebi:mass "79.90400" ; chebi:monoisotopicmass "78.91834" ; chebi:smiles "[Br]" ; oboInOwl:hasDbXref "WebElements:Br" ; oboInOwl:hasExactSynonym "bromine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "35Br", "Br", "Brom", "brome", "bromine", "bromo", "bromum" ; oboInOwl:id "CHEBI:22927" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bromine atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_24473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_22928 oboInOwl:hasExactSynonym "bromine molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bromine compounds", "bromine molecular entities" ; oboInOwl:id "CHEBI:22928" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bromine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22927 ] . obo:CHEBI_22951 obo:IAO_0000115 "Any ketone that is butane substituted by an oxo group at unspecified position." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "butanones" ; oboInOwl:id "CHEBI:22951" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "butanone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_22977 chebi:charge "0" ; chebi:formula "Cd" ; chebi:inchi "InChI=1S/Cd" ; chebi:inchikey "BDOSMKKIYDKNTQ-UHFFFAOYSA-N" ; chebi:mass "112.41100" ; chebi:monoisotopicmass "113.90336" ; chebi:smiles "[Cd]" ; oboInOwl:hasDbXref "CAS:7440-43-9", "KEGG:C01413", "WebElements:Cd" ; oboInOwl:hasExactSynonym "cadmium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "48Cd", "Cd", "Kadmium", "cadmio", "cadmium" ; oboInOwl:id "CHEBI:22977" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cadmium atom" ; rdfs:subClassOf obo:CHEBI_33340 . obo:CHEBI_22984 chebi:charge "0" ; chebi:formula "Ca" ; chebi:inchi "InChI=1S/Ca" ; chebi:inchikey "OYPRJOBELJOOCE-UHFFFAOYSA-N" ; chebi:mass "40.07800" ; chebi:monoisotopicmass "39.96259" ; chebi:smiles "[Ca]" ; oboInOwl:hasDbXref "CAS:7440-70-2", "DrugBank:DB01373", "KEGG:C00076", "WebElements:Ca" ; oboInOwl:hasExactSynonym "calcium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "20Ca", "Ca", "Calcium", "Kalzium", "calcio", "calcium" ; oboInOwl:id "CHEBI:22984" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "calcium atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_22313, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_22985 oboInOwl:hasExactSynonym "calcium molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium compounds", "calcium molecular entities" ; oboInOwl:id "CHEBI:22985" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "calcium molecular entity" ; rdfs:subClassOf obo:CHEBI_33299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22984 ] . obo:CHEBI_23003 obo:IAO_0000115 "Any ester of carbamic acid or its N-substituted derivatives." ; oboInOwl:hasDbXref "Wikipedia:Carbamate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbamate esters", "carbamates" ; oboInOwl:id "CHEBI:23003" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbamate ester" ; rdfs:subClassOf obo:CHEBI_33308, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_28616 ] . obo:CHEBI_23004 obo:IAO_0000115 "The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid." ; chebi:charge "0" ; chebi:formula "CH2NO" ; chebi:mass "44.03272" ; chebi:monoisotopicmass "44.01364" ; chebi:smiles "*C(N)=O" ; oboInOwl:hasDbXref "PMID:24168430" ; oboInOwl:hasExactSynonym "carbamoyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-C(O)NH2", "-CONH2", "aminocarbonyl", "carbamyl", "carbamyl group", "carboxamide" ; oboInOwl:id "CHEBI:23004" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbamoyl group" ; rdfs:subClassOf obo:CHEBI_27207, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_28616 ] . obo:CHEBI_23014 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon oxides", "oxides of carbon" ; oboInOwl:id "CHEBI:23014" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbon oxide" ; rdfs:subClassOf obo:CHEBI_25701, obo:CHEBI_36963 . obo:CHEBI_23019 chebi:charge "0" ; chebi:formula "CO" ; chebi:mass "28.01010" ; chebi:monoisotopicmass "27.99491" ; chebi:smiles "O=C(*)*" ; oboInOwl:hasExactSynonym "carbonyl", "carbonyl group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym ">C=O" ; oboInOwl:id "CHEBI:23019" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbonyl group" ; rdfs:subClassOf obo:CHEBI_51422 . obo:CHEBI_23114 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chloride salts", "chlorides" ; oboInOwl:id "CHEBI:23114" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chloride salt" ; rdfs:subClassOf obo:CHEBI_23117, obo:CHEBI_33958, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_17996 ] . obo:CHEBI_23116 chebi:charge "0" ; chebi:formula "Cl" ; chebi:inchi "InChI=1S/Cl" ; chebi:inchikey "ZAMOUSCENKQFHK-UHFFFAOYSA-N" ; chebi:mass "35.45270" ; chebi:monoisotopicmass "34.96885" ; chebi:smiles "[Cl]" ; oboInOwl:hasDbXref "WebElements:Cl" ; oboInOwl:hasExactSynonym "chlorine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "17Cl", "Chlor", "Cl", "chlore", "chlorine", "chlorum", "cloro" ; oboInOwl:id "CHEBI:23116" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chlorine atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_24473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_23117 obo:IAO_0000115 "A halogen molecular entity containing one or more atoms of chlorine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23117" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chlorine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_23116 ] . obo:CHEBI_23357 obo:IAO_0000115 "An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group)." ; oboInOwl:hasDbXref "Wikipedia:Cofactor_(biochemistry)" ; oboInOwl:hasExactSynonym "cofactor", "cofactors" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23357" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cofactor" ; rdfs:subClassOf obo:CHEBI_52206 . obo:CHEBI_23359 obo:IAO_0000115 "An alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum." ; chebi:charge "0" ; chebi:formula "C22H25NO6" ; chebi:inchi "InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)" ; chebi:inchikey "IAKHMKGGTNLKSZ-UHFFFAOYSA-N" ; chebi:mass "399.43704" ; chebi:monoisotopicmass "399.16819" ; chebi:smiles "COc1cc2CCC(NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC" ; oboInOwl:hasDbXref "Beilstein:2228812", "CAS:54192-66-4", "DrugBank:DB01394", "HMDB:HMDB0015466", "LINCS:LSM-6449", "PMID:10680067", "PMID:24074178", "PMID:7200520", "PMID:9819133", "Reaxys:2228812" ; oboInOwl:hasExactSynonym "N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23359" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "colchicine" ; rdfs:subClassOf obo:CHEBI_22160, obo:CHEBI_22315, obo:CHEBI_35618, obo:CHEBI_38032, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_61951 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ] . obo:CHEBI_23367 obo:IAO_0000115 "Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity." ; oboInOwl:hasExactSynonym "molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "entidad molecular", "entidades moleculares", "entite moleculaire", "molecular entities", "molekulare Entitaet" ; oboInOwl:id "CHEBI:23367" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "molecular entity" ; rdfs:subClassOf obo:CHEBI_24431 . obo:CHEBI_23377 oboInOwl:hasExactSynonym "copper molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "copper compounds", "copper molecular entities" ; oboInOwl:id "CHEBI:23377" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "copper molecular entity" ; rdfs:subClassOf obo:CHEBI_33745, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_28694 ] . obo:CHEBI_23423 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23423" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "pseudohalogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24833 . obo:CHEBI_23447 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic nucleotides" ; oboInOwl:id "CHEBI:23447" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic nucleotide" ; rdfs:subClassOf obo:CHEBI_36976 . obo:CHEBI_23449 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cyclopeptid", "Zyklopeptid", "cyclic peptides", "peptide cyclique", "peptido ciclico" ; oboInOwl:id "CHEBI:23449" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic peptide" ; rdfs:subClassOf obo:CHEBI_16670 . obo:CHEBI_23451 obo:IAO_0000115 "A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom." ; oboInOwl:hasExactSynonym "cyclitols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23451" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclitol" ; rdfs:subClassOf obo:CHEBI_26191 . obo:CHEBI_23480 obo:IAO_0000115 "An alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23480" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclohexanols" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_23493 obo:IAO_0000115 "Cyclopentane and its derivatives formed by substitution." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23493" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclopentanes" ; rdfs:subClassOf obo:CHEBI_33598 . obo:CHEBI_23495 obo:IAO_0000115 "An alcohol in which one or more hydroxy groups are attached to a cyclopentane skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23495" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclopentanols" ; rdfs:subClassOf obo:CHEBI_23493, obo:CHEBI_30879 . obo:CHEBI_23509 obo:IAO_0000115 "An amino acid derivative resulting from reaction of cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of cysteine by a heteroatom. The definition normally excludes peptides containing cysteine residues." ; oboInOwl:hasAlternativeId "CHEBI:25309" ; oboInOwl:hasExactSynonym "cysteine derivative" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cysteine derivatives" ; oboInOwl:id "CHEBI:23509" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cysteine derivative" ; rdfs:subClassOf obo:CHEBI_83821, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_15356 ] . obo:CHEBI_23677 obo:IAO_0000115 "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "diazoles" ; oboInOwl:id "CHEBI:23677" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diazole" ; rdfs:subClassOf obo:CHEBI_68452 . obo:CHEBI_237958 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:237958" ; oboInOwl:inSubset chebi2:_STAR ; a owl:Class ; rdfs:label "({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate" ; rdfs:subClassOf obo:CHEBI_37045, obo:CHEBI_37096, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50733 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_57299 ] . obo:CHEBI_23849 obo:IAO_0000115 "Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups)." ; oboInOwl:hasDbXref "LIPID_MAPS_class:LMPR0104" ; oboInOwl:hasExactSynonym "diterpenoids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C20 isoprenoids", "diterpenoides" ; oboInOwl:id "CHEBI:23849" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diterpenoid" ; rdfs:subClassOf obo:CHEBI_26873, [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_35190 ] . obo:CHEBI_23888 obo:IAO_0000115 "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "drugs", "medicine" ; oboInOwl:id "CHEBI:23888" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "drug" ; rdfs:subClassOf obo:CHEBI_52217 . obo:CHEBI_23905 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic anions" ; oboInOwl:id "CHEBI:23905" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic anion" ; rdfs:subClassOf obo:CHEBI_22563, obo:CHEBI_24867 . obo:CHEBI_23906 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic cations" ; oboInOwl:id "CHEBI:23906" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic cation" ; rdfs:subClassOf obo:CHEBI_24867, obo:CHEBI_36916 . obo:CHEBI_23924 obo:IAO_0000115 "A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction." ; oboInOwl:hasExactSynonym "enzyme inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "enzyme inhibitors", "inhibidor enzimatico", "inhibidores enzimaticos", "inhibiteur enzymatique", "inhibiteurs enzymatiques" ; oboInOwl:id "CHEBI:23924" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "enzyme inhibitor" ; rdfs:subClassOf obo:CHEBI_35222, obo:CHEBI_52206 . obo:CHEBI_23981 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ethanolamine" ; oboInOwl:id "CHEBI:23981" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ethanolamines" ; rdfs:subClassOf obo:CHEBI_22478 . obo:CHEBI_23982 obo:IAO_0000115 "Any primary alcohol based on an ethanol skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:23982" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ethanols" ; rdfs:subClassOf obo:CHEBI_15734 . obo:CHEBI_23994 obo:IAO_0000115 "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol." ; chebi:charge "0" ; chebi:formula "C3H8O3S" ; chebi:inchi "InChI=1S/C3H8O3S/c1-3-6-7(2,4)5/h3H2,1-2H3" ; chebi:inchikey "PLUBXMRUUVWRLT-UHFFFAOYSA-N" ; chebi:mass "124.15900" ; chebi:monoisotopicmass "124.01942" ; chebi:smiles "CCOS(C)(=O)=O" ; oboInOwl:hasDbXref "CAS:62-50-0", "KEGG:C19239", "PMID:16039156", "PMID:19797863", "PMID:20102787", "PMID:24475756", "PMID:24524729", "PMID:24531730", "PMID:24728647", "PMID:6936603", "PMID:7285888", "Reaxys:773969", "Wikipedia:Ethyl_methanesulfonate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EMS", "ethyl mesylate", "ethyl methanesulphonate", "methylsulfonic acid ethyl ester", "methylsulfonic acid, ethyl ester" ; oboInOwl:id "CHEBI:23994" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ethyl methanesulfonate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25223, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22333 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35610 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50903 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ] . obo:CHEBI_24026 obo:IAO_0000115 "An aliphatic alcohol consisting of a chain of 3 to greater than 27 carbon atoms. Fatty alcohols may be saturated or unsaturated and may be branched or unbranched." ; chebi:charge "0" ; chebi:formula "HOR" ; chebi:mass "17.007" ; chebi:monoisotopicmass "17.00274" ; chebi:smiles "O[*]" ; oboInOwl:hasDbXref "LIPID_MAPS_class:LMFA05", "MetaCyc:Fatty-Alcohols", "Wikipedia:Fatty_alcohol" ; oboInOwl:hasExactSynonym "fatty alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Fettalkohol", "Fettalkohole", "a fatty alcohol", "alcool gras", "fatty alcohols" ; oboInOwl:id "CHEBI:24026" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fatty alcohol" ; rdfs:subClassOf obo:CHEBI_30879, obo:CHEBI_61697 . obo:CHEBI_24061 chebi:charge "0" ; chebi:formula "F" ; chebi:inchi "InChI=1S/F" ; chebi:inchikey "YCKRFDGAMUMZLT-UHFFFAOYSA-N" ; chebi:mass "18.99840" ; chebi:monoisotopicmass "18.99840" ; chebi:smiles "[F]" ; oboInOwl:hasDbXref "CAS:7782-41-4", "WebElements:F" ; oboInOwl:hasExactSynonym "fluorine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "9F", "F", "Fluor", "fluor", "fluorine", "fluorum" ; oboInOwl:id "CHEBI:24061" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluorine atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_24473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_24062 oboInOwl:hasExactSynonym "fluorine molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fluorine compounds", "fluorine molecular entities" ; oboInOwl:id "CHEBI:24062" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluorine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_24061 ] . obo:CHEBI_24067 obo:IAO_0000115 "A haloalkane that is an alkane in which at least one hydrogen atom has been replaced by a fluorine atom." ; oboInOwl:hasExactSynonym "fluoroalkane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fluoroalkanes" ; oboInOwl:id "CHEBI:24067" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluoroalkane" ; rdfs:subClassOf obo:CHEBI_24469, obo:CHEBI_37143 . obo:CHEBI_24129 obo:IAO_0000115 "Compounds containing at least one furan ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxacyclopenta-2,4-dienes" ; oboInOwl:id "CHEBI:24129" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "furans" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38104 . obo:CHEBI_24384 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24384" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glycogens" ; rdfs:subClassOf obo:CHEBI_37163 . obo:CHEBI_24400 obo:IAO_0000115 "A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively." ; oboInOwl:hasExactSynonym "glycosides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "O-glycoside", "O-glycosides", "glycosides" ; oboInOwl:id "CHEBI:24400" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glycoside" ; rdfs:subClassOf obo:CHEBI_63161 . obo:CHEBI_24431 obo:IAO_0000115 "A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances." ; oboInOwl:hasExactSynonym "chemical entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24431" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chemical entity" . obo:CHEBI_24432 obo:IAO_0000115 "A role played by the molecular entity or part thereof within a biological context." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "biological function" ; oboInOwl:id "CHEBI:24432" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "biological role" ; rdfs:subClassOf obo:CHEBI_50906 . obo:CHEBI_24433 obo:IAO_0000115 "A defined linked collection of atoms or a single atom within a molecular entity." ; oboInOwl:hasExactSynonym "group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Gruppe", "Rest", "groupe", "grupo", "grupos" ; oboInOwl:id "CHEBI:24433" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "group" ; rdfs:subClassOf obo:CHEBI_24431, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33250 ] . obo:CHEBI_24469 obo:IAO_0000115 "A halohydrocarbon that is an alkane in which at least one hydrogen atom has been replaced by with a halogen atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkyl halide", "alkyl halides", "haloalkanes" ; oboInOwl:id "CHEBI:24469" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "haloalkane" ; rdfs:subClassOf obo:CHEBI_24472 . obo:CHEBI_24471 oboInOwl:hasExactSynonym "halogen molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogen compounds", "halogen molecular entities" ; oboInOwl:id "CHEBI:24471" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_24473 ] . obo:CHEBI_24472 obo:IAO_0000115 "A compound derived from a hydrocarbon by replacing a hydrogen atom with a halogen atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogenated hydrocarbons", "halohydrocarbons" ; oboInOwl:id "CHEBI:24472" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halohydrocarbon" ; rdfs:subClassOf obo:CHEBI_17792, [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_24632 ] . obo:CHEBI_24473 oboInOwl:hasExactSynonym "halogen", "halogens" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Halogene", "group 17 elements", "group VII elements", "halogene", "halogenes", "halogeno", "halogenos" ; oboInOwl:id "CHEBI:24473" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halogen" ; rdfs:subClassOf obo:CHEBI_25585, obo:CHEBI_33560 . obo:CHEBI_24527 obo:IAO_0000115 "A substance used to destroy plant pests." ; oboInOwl:hasDbXref "Wikipedia:Herbicide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Herbizid", "Unkrautbekaempfungsmittel", "Unkrautvertilgungsmittel", "Wildkrautbekaempfungsmittel", "herbicides" ; oboInOwl:id "CHEBI:24527" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "herbicide" ; rdfs:subClassOf obo:CHEBI_25944 . obo:CHEBI_24532 obo:IAO_0000115 "A cyclic compound having as ring members atoms of carbon and at least of one other element." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic heterocycle", "organic heterocyclic compounds" ; oboInOwl:id "CHEBI:24532" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic heterocyclic compound" ; rdfs:subClassOf obo:CHEBI_33285, obo:CHEBI_33832, obo:CHEBI_5686 . obo:CHEBI_24533 obo:IAO_0000115 "A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond." ; oboInOwl:hasExactSynonym "heterodetic cyclic peptide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterodetic cyclic peptides", "peptide cyclique heterodetique", "peptido ciclico heterodetico" ; oboInOwl:id "CHEBI:24533" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heterodetic cyclic peptide" ; rdfs:subClassOf obo:CHEBI_23449 . obo:CHEBI_24621 obo:IAO_0000115 "Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "endocrine", "hormones" ; oboInOwl:id "CHEBI:24621" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hormone" ; rdfs:subClassOf obo:CHEBI_33280, obo:CHEBI_48705 . obo:CHEBI_24632 obo:IAO_0000115 "A compound consisting of carbon and hydrogen only." ; oboInOwl:hasExactSynonym "hydrocarbon", "hydrocarbons" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kohlenwasserstoff", "Kohlenwasserstoffe", "hidrocarburo", "hidrocarburos", "hydrocarbure" ; oboInOwl:id "CHEBI:24632" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrocarbon" ; rdfs:subClassOf obo:CHEBI_33245 . obo:CHEBI_24651 obo:IAO_0000115 "Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-))." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24651" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydroxides" ; rdfs:subClassOf obo:CHEBI_25806, obo:CHEBI_33608, obo:CHEBI_37577, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_43176 ] . obo:CHEBI_24757 obo:IAO_0000115 "A chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water." ; chebi:charge "0" ; chebi:formula "ClHO" ; chebi:inchi "InChI=1S/ClHO/c1-2/h2H" ; chebi:inchikey "QWPPOHNGKGFGJK-UHFFFAOYSA-N" ; chebi:mass "52.46004" ; chebi:monoisotopicmass "51.97159" ; chebi:smiles "OCl" ; oboInOwl:hasDbXref "CAS:7790-92-3", "Gmelin:688", "PMID:11640916", "PMID:12079432", "PMID:12215218", "PMID:15589368", "PMID:7487057", "PMID:8072005" ; oboInOwl:hasExactSynonym "chloranol", "hydroxidochlorine", "hypochlorous acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Chlor(I)-saeure", "HClO", "HOCl", "[ClOH]", "hypochloric acid", "hypochlorige Saeure" ; oboInOwl:id "CHEBI:24757" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hypochlorous acid" ; rdfs:subClassOf obo:CHEBI_26523, obo:CHEBI_33426, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38462 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76797 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29222 ] . obo:CHEBI_24780 obo:IAO_0000115 "A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24780" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "imidazoles" ; rdfs:subClassOf obo:CHEBI_23677 . obo:CHEBI_24782 oboInOwl:hasExactSynonym "imide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "imides" ; oboInOwl:id "CHEBI:24782" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "imide" ; rdfs:subClassOf obo:CHEBI_33257 . obo:CHEBI_24828 obo:IAO_0000115 "Any compound containing an indole skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24828" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "indoles" ; rdfs:subClassOf obo:CHEBI_22728 . obo:CHEBI_24833 obo:IAO_0000115 "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ; oboInOwl:hasExactSynonym "oxoacid", "oxoacids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxacids", "oxiacids", "oxo acid", "oxy-acids", "oxyacids" ; oboInOwl:id "CHEBI:24833" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxoacid" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_24651, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39141 ] . obo:CHEBI_24834 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic anions" ; oboInOwl:id "CHEBI:24834" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic anion" ; rdfs:subClassOf obo:CHEBI_22563, obo:CHEBI_36914 . obo:CHEBI_24835 obo:IAO_0000115 "A molecular entity that contains no carbon." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anorganische Verbindungen", "inorganic compounds", "inorganic entity", "inorganic molecular entities", "inorganics" ; oboInOwl:id "CHEBI:24835" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic molecular entity" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_24836 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic oxides" ; oboInOwl:id "CHEBI:24836" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic oxide" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_25741 . obo:CHEBI_24837 obo:IAO_0000115 "Compounds of structure ROOR' in which R and R' are inorganic groups." ; oboInOwl:hasExactSynonym "inorganic peroxide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic peroxides" ; oboInOwl:id "CHEBI:24837" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic peroxide" ; rdfs:subClassOf obo:CHEBI_24836, obo:CHEBI_25940 . obo:CHEBI_24839 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anorganisches Salz", "inorganic salts" ; oboInOwl:id "CHEBI:24839" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic salt" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_24866 . obo:CHEBI_24848 obo:IAO_0000115 "Any cyclohexane-1,2,3,4,5,6-hexol." ; chebi:charge "0" ; chebi:formula "C6H12O6" ; chebi:inchi "InChI=1S/C6H12O6/c7-1-2(8)4(10)6(12)5(11)3(1)9/h1-12H" ; chebi:inchikey "CDAISMWEOUEBRE-UHFFFAOYSA-N" ; chebi:mass "180.15588" ; chebi:monoisotopicmass "180.06339" ; chebi:smiles "OC1C(O)C(O)C(O)C(O)C1O" ; oboInOwl:hasExactSynonym "inositol", "inositols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2,3,4,5,6-cyclohexanehexol", "inositols" ; oboInOwl:id "CHEBI:24848" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inositol" ; rdfs:subClassOf obo:CHEBI_23451, obo:CHEBI_37206 . obo:CHEBI_24852 obo:IAO_0000115 "Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects." ; oboInOwl:hasDbXref "Wikipedia:Insecticide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "insecticides" ; oboInOwl:id "CHEBI:24852" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "insecticide" ; rdfs:subClassOf obo:CHEBI_25944 . obo:CHEBI_24858 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iodide salts", "iodides" ; oboInOwl:id "CHEBI:24858" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iodide salt" ; rdfs:subClassOf obo:CHEBI_24860, obo:CHEBI_33958, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16382 ] . obo:CHEBI_24859 obo:IAO_0000115 "Chemical element with atomic number 53." ; chebi:charge "0" ; chebi:formula "I" ; chebi:inchi "InChI=1S/I" ; chebi:inchikey "ZCYVEMRRCGMTRW-UHFFFAOYSA-N" ; chebi:mass "126.90447" ; chebi:monoisotopicmass "126.90447" ; chebi:smiles "[I]" ; oboInOwl:hasDbXref "WebElements:I" ; oboInOwl:hasExactSynonym "iodine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "53I", "I", "Iod", "J", "Jod", "iode", "iodine", "iodium", "yodo" ; oboInOwl:id "CHEBI:24859" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iodine atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_24473, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ] . obo:CHEBI_24860 oboInOwl:hasExactSynonym "iodine molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iodine compounds", "iodine molecular entities" ; oboInOwl:id "CHEBI:24860" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iodine molecular entity" ; rdfs:subClassOf obo:CHEBI_24471, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_24859 ] . obo:CHEBI_24866 obo:IAO_0000115 "A salt is an assembly of cations and anions." ; oboInOwl:hasExactSynonym "salt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Salz", "Salze", "ionic compound", "ionic compounds", "sal", "sales", "salts", "sel", "sels" ; oboInOwl:id "CHEBI:24866" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "salt" ; rdfs:subClassOf obo:CHEBI_37577, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22563 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_36916 ] . obo:CHEBI_24867 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic ions" ; oboInOwl:id "CHEBI:24867" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic ion" ; rdfs:subClassOf obo:CHEBI_24870, obo:CHEBI_33238 . obo:CHEBI_24868 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic salts", "organisches Salz" ; oboInOwl:id "CHEBI:24868" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic salt" ; rdfs:subClassOf obo:CHEBI_24866 . obo:CHEBI_24870 obo:IAO_0000115 "A molecular entity having a net electric charge." ; oboInOwl:hasExactSynonym "Ion", "ion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ionen", "iones", "ions" ; oboInOwl:id "CHEBI:24870" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ion" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_24873 oboInOwl:hasExactSynonym "iron molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iron compounds", "iron molecular entities" ; oboInOwl:id "CHEBI:24873" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iron molecular entity" ; rdfs:subClassOf obo:CHEBI_33744, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_18248 ] . obo:CHEBI_24913 obo:IAO_0000115 "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives." ; oboInOwl:hasDbXref "LIPID_MAPS_class:LMPR01", "PMID:12769708", "PMID:19219049" ; oboInOwl:hasExactSynonym "isoprenoid", "isoprenoids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isoprenoids" ; oboInOwl:id "CHEBI:24913" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isoprenoid" ; rdfs:subClassOf obo:CHEBI_18059 . obo:CHEBI_24921 obo:IAO_0000115 "Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isoquinoline alkaloids" ; oboInOwl:id "CHEBI:24921" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isoquinoline alkaloid" ; rdfs:subClassOf obo:CHEBI_22315 . obo:CHEBI_24922 obo:IAO_0000115 "A class of organic heteropolycyclic compound consisting of isoquinoline and its substitution derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:24922" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isoquinolines" ; rdfs:subClassOf obo:CHEBI_38101, obo:CHEBI_38166 . obo:CHEBI_25000 obo:IAO_0000115 "Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring." ; oboInOwl:hasExactSynonym "lactone", "lactones" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Lacton", "Lakton", "Laktone", "lactona", "lactonas" ; oboInOwl:id "CHEBI:25000" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "lactone" ; rdfs:subClassOf obo:CHEBI_33308, obo:CHEBI_38104 . obo:CHEBI_25016 chebi:charge "0" ; chebi:formula "Pb" ; chebi:inchi "InChI=1S/Pb" ; chebi:inchikey "WABPQHHGFIMREM-UHFFFAOYSA-N" ; chebi:mass "207.20000" ; chebi:monoisotopicmass "207.97665" ; chebi:smiles "[Pb]" ; oboInOwl:hasDbXref "KEGG:C06696", "WebElements:Pb" ; oboInOwl:hasExactSynonym "lead" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "82Pb", "Blei", "Pb", "lead", "plomb", "plomo", "plumbum" ; oboInOwl:id "CHEBI:25016" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "lead atom" ; rdfs:subClassOf obo:CHEBI_33306, obo:CHEBI_33521 . obo:CHEBI_25094 obo:IAO_0000115 "A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6." ; chebi:charge "0" ; chebi:formula "C6H14N2O2" ; chebi:inchi "InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)" ; chebi:inchikey "KDXKERNSBIXSRK-UHFFFAOYSA-N" ; chebi:mass "146.18764" ; chebi:monoisotopicmass "146.10553" ; chebi:smiles "NCCCCC(N)C(O)=O" ; oboInOwl:hasDbXref "Beilstein:1616991", "CAS:70-54-2", "Gmelin:279284", "KEGG:C16440", "PMID:17439666", "PMID:22264337", "Reaxys:1616991", "Wikipedia:Lysine" ; oboInOwl:hasExactSynonym "2,6-diaminohexanoic acid", "lysine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "K", "LYS", "Lysin", "alpha,epsilon-diaminocaproic acid" ; oboInOwl:id "CHEBI:25094" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "lysine" ; rdfs:subClassOf obo:CHEBI_26167, obo:CHEBI_33704, obo:CHEBI_35987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50339 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_30776 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32563 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32564 ] . obo:CHEBI_25105 obo:IAO_0000115 "A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Makrolidantibiotika", "macrolide antibiotics" ; oboInOwl:id "CHEBI:25105" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "macrolide antibiotic" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25106, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_25106 obo:IAO_0000115 "A macrocyclic lactone with a ring of twelve or more members derived from a polyketide." ; oboInOwl:hasDbXref "Wikipedia:Macrolide" ; oboInOwl:hasExactSynonym "macrolide", "macrolides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Makrolid", "macrolides" ; oboInOwl:id "CHEBI:25106" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "macrolide" ; rdfs:subClassOf obo:CHEBI_26188, obo:CHEBI_63944 . obo:CHEBI_25107 chebi:charge "0" ; chebi:formula "Mg" ; chebi:inchi "InChI=1S/Mg" ; chebi:inchikey "FYYHWMGAXLPEAU-UHFFFAOYSA-N" ; chebi:mass "24.30500" ; chebi:monoisotopicmass "23.98504" ; chebi:smiles "[Mg]" ; oboInOwl:hasDbXref "CAS:7439-95-4", "DrugBank:DB01378", "Gmelin:16207", "KEGG:C00305", "WebElements:Mg" ; oboInOwl:hasExactSynonym "magnesium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "12Mg", "Magnesium", "Mg", "magnesio", "magnesium" ; oboInOwl:id "CHEBI:25107" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "magnesium atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_22313, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_25195 chebi:charge "0" ; chebi:formula "Hg" ; chebi:inchi "InChI=1S/Hg" ; chebi:inchikey "QSHDDOUJBYECFT-UHFFFAOYSA-N" ; chebi:mass "200.59000" ; chebi:monoisotopicmass "201.97064" ; chebi:smiles "[Hg]" ; oboInOwl:hasDbXref "CAS:7439-97-6", "WebElements:Hg" ; oboInOwl:hasExactSynonym "mercury" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "80Hg", "Hg", "Quecksilber", "azogue", "hydrargyrum", "liquid silver", "mercure", "mercurio", "mercury", "quicksilver" ; oboInOwl:id "CHEBI:25195" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mercury atom" ; rdfs:subClassOf obo:CHEBI_33340 . obo:CHEBI_25212 obo:IAO_0000115 "Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites." ; oboInOwl:hasAlternativeId "CHEBI:26619", "CHEBI:35220" ; oboInOwl:hasExactSynonym "metabolite" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metabolites", "primary metabolites", "secondary metabolites" ; oboInOwl:id "CHEBI:25212" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "metabolite" ; rdfs:subClassOf obo:CHEBI_52206 . obo:CHEBI_25213 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a metal cation", "metal cations" ; oboInOwl:id "CHEBI:25213" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "metal cation" ; rdfs:subClassOf obo:CHEBI_23906, obo:CHEBI_36915 . obo:CHEBI_25216 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metalloporphyrins", "metaloporphyrins" ; oboInOwl:id "CHEBI:25216" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "metalloporphyrin" ; rdfs:subClassOf obo:CHEBI_26214, obo:CHEBI_33240, obo:CHEBI_33909 . obo:CHEBI_25223 obo:IAO_0000115 "An organosulfonic ester resulting from the formal condensation of methanesulfonic acid with the hydroxy group of an alcohol, phenol, heteroarenol, or enol." ; chebi:charge "0" ; chebi:formula "CH3O3SR" ; chebi:mass "95.099" ; chebi:monoisotopicmass "94.98029" ; chebi:smiles "CS(O*)(=O)=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mesylate ester", "mesylate esters", "methanesulfonic acid esters" ; oboInOwl:id "CHEBI:25223" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methanesulfonate ester" ; rdfs:subClassOf obo:CHEBI_48544, obo:CHEBI_83347 . obo:CHEBI_25224 obo:IAO_0000115 "A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid." ; chebi:charge "-1" ; chebi:formula "CH3O3S" ; chebi:inchi "InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)/p-1" ; chebi:inchikey "AFVFQIVMOAPDHO-UHFFFAOYSA-M" ; chebi:mass "95.09872" ; chebi:monoisotopicmass "94.98084" ; chebi:smiles "CS([O-])(=O)=O" ; oboInOwl:hasDbXref "MetaCyc:CPD-3746", "UM-BBD_compID:c0347" ; oboInOwl:hasExactSynonym "methanesulfonate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methylsulfonate" ; oboInOwl:id "CHEBI:25224" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methanesulfonate" ; rdfs:subClassOf obo:CHEBI_62081, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_27376 ] . obo:CHEBI_25248 obo:IAO_0000115 "Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol." ; chebi:charge "0" ; chebi:formula "C2H3O2R" ; chebi:mass "59.044" ; chebi:monoisotopicmass "59.01330" ; chebi:smiles "COC([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carboxylic acid methyl ester", "carboxylic acid methyl esters" ; oboInOwl:id "CHEBI:25248" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methyl ester" ; rdfs:subClassOf obo:CHEBI_33308, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17790 ] . obo:CHEBI_25255 obo:IAO_0000115 "A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol." ; chebi:charge "0" ; chebi:formula "C2H6O3S" ; chebi:inchi "InChI=1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3" ; chebi:inchikey "MBABOKRGFJTBAE-UHFFFAOYSA-N" ; chebi:mass "110.13200" ; chebi:monoisotopicmass "110.00377" ; chebi:smiles "COS(C)(=O)=O" ; oboInOwl:hasDbXref "CAS:66-27-3", "KEGG:C19181", "MetaCyc:CPD-7038", "PMID:11016630", "PMID:14761437", "PMID:16764919", "PMID:21353429", "PMID:21860482", "PMID:22907509", "PMID:23117069", "PMID:23384783", "PMID:23483329", "Reaxys:1098586", "Wikipedia:Methyl_methanesulfonate" ; oboInOwl:hasExactSynonym "methyl methanesulfonate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CB1540", "MMS", "Methanesulfonic acid methyl ester", "Methyl mesylate", "as-Dimethyl sulfite" ; oboInOwl:id "CHEBI:25255" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methyl methanesulfonate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25223, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22333 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50903 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_68495 ] . obo:CHEBI_25348 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methylxanthines" ; oboInOwl:id "CHEBI:25348" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methylxanthine" ; rdfs:subClassOf obo:CHEBI_26385, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_15318 ] . obo:CHEBI_25367 obo:IAO_0000115 "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom." ; oboInOwl:hasExactSynonym "molecule" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Molekuel", "molecula", "molecules", "neutral molecular compounds" ; oboInOwl:id "CHEBI:25367" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "molecule" ; rdfs:subClassOf obo:CHEBI_36357 . obo:CHEBI_25375 obo:IAO_0000115 "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monamines", "monoamines" ; oboInOwl:id "CHEBI:25375" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoamine molecular messenger" ; rdfs:subClassOf obo:CHEBI_63534, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33280 ] . obo:CHEBI_25384 obo:IAO_0000115 "An oxoacid containing a single carboxy group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monocarboxylic acids" ; oboInOwl:id "CHEBI:25384" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monocarboxylic acid" ; rdfs:subClassOf obo:CHEBI_33575, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_35757 ] . obo:CHEBI_25413 obo:IAO_0000115 "Any fatty acid with one double or triple bond in the fatty acid chain and singly bonded carbon atoms in the rest of the chain. MUFAs have positive effects on the cardiovascular system, and in diabetes treatment." ; oboInOwl:hasDbXref "PMID:10584045", "PMID:12936956" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "MUFA", "MUFAs", "monounsaturated fatty acids" ; oboInOwl:id "CHEBI:25413" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monounsaturated fatty acid" ; rdfs:subClassOf obo:CHEBI_27208, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_82680 ] . obo:CHEBI_25414 chebi:charge "+1" ; chebi:mass "0.00000" ; chebi:smiles "[*+]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic monocations", "monovalent inorganic cations" ; oboInOwl:id "CHEBI:25414" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic monocation" ; rdfs:subClassOf obo:CHEBI_23906 . obo:CHEBI_25435 obo:IAO_0000115 "An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution." ; oboInOwl:hasDbXref "Wikipedia:Mutagen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mutagene", "mutagenes", "mutagenic agent", "mutageno", "mutagenos", "mutagens" ; oboInOwl:id "CHEBI:25435" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mutagen" ; rdfs:subClassOf obo:CHEBI_50902 . obo:CHEBI_25442 obo:IAO_0000115 "Poisonous substance produced by fungi." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fungal toxins", "mycotoxins" ; oboInOwl:id "CHEBI:25442" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mycotoxin" ; rdfs:subClassOf obo:CHEBI_27026, obo:CHEBI_76946 . obo:CHEBI_25491 obo:IAO_0000115 "A substance used to destroy pests of the phylum Nematoda (roundworms)." ; oboInOwl:hasDbXref "Wikipedia:Nematicide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nematicides", "nematocide", "nematocides" ; oboInOwl:id "CHEBI:25491" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nematicide" ; rdfs:subClassOf obo:CHEBI_25944 . obo:CHEBI_25512 obo:IAO_0000115 "An endogenous compound that is used to transmit information across the synapse between a neuron and another cell." ; oboInOwl:hasDbXref "Wikipedia:Neurotransmitter" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "neurotransmitters" ; oboInOwl:id "CHEBI:25512" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "neurotransmitter" ; rdfs:subClassOf obo:CHEBI_33280 . obo:CHEBI_2555 obo:IAO_0000115 "The oxime carbamate resulting from the addition of 2-methyl-2-(methylsulfanyl)propanaldoxime to methyl isocyanate. A member of the class of oxime carbamate insecticides, aldicarb is a mixture of E and Z isomers; it is not known which isomer is more active." ; chebi:charge "0" ; chebi:formula "C7H14N2O2S" ; chebi:inchi "InChI=1S/C7H14N2O2S/c1-7(2,12-4)5-9-11-6(10)8-3/h5H,1-4H3,(H,8,10)" ; chebi:inchikey "QGLZXHRNAYXIBU-UHFFFAOYSA-N" ; chebi:mass "190.26300" ; chebi:monoisotopicmass "190.07760" ; chebi:smiles "[H]C(=NOC(=O)NC)C(C)(C)SC" ; oboInOwl:hasDbXref "Beilstein:2046931", "CAS:116-06-3", "KEGG:C11015", "LINCS:LSM-20978", "PPDB:19", "Patent:US3217037" ; oboInOwl:hasExactSynonym "2-methyl-N-[(methylcarbamoyl)oxy]-2-(methylsulfanyl)propan-1-imine", "Aldicarb", "aldicarb" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-Methyl-2-(methylthio)propanal, O-((methylamino)carbonyl)oxime", "2-Methyl-2-(methylthio)propionaldehyde O-(methylcarbamoyl)oxime", "2-Methyl-2-methylthio-propionaldehyd-O-(N-methyl-carbamoyl)-oxim", "aldicarbe" ; oboInOwl:id "CHEBI:2555" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aldicarb" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_23003, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22153 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25491 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38461 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_59059 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_60330 ] . obo:CHEBI_25555 chebi:charge "0" ; chebi:formula "N" ; chebi:mass "14.007" ; chebi:monoisotopicmass "14.00307" ; oboInOwl:hasDbXref "WebElements:N" ; oboInOwl:hasExactSynonym "nitrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "7N", "N", "Stickstoff", "azote", "nitrogen", "nitrogeno" ; oboInOwl:id "CHEBI:25555" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nitrogen atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25585, obo:CHEBI_33300, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_25579 obo:IAO_0000115 "Any ketone that is nonane substituted by an oxo group at unspecified position." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nonanones" ; oboInOwl:id "CHEBI:25579" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nonanone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_25585 oboInOwl:hasExactSynonym "nonmetal" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Nichtmetall", "Nichtmetalle", "no metal", "no metales", "non-metal", "non-metaux", "nonmetal", "nonmetals" ; oboInOwl:id "CHEBI:25585" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nonmetal atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_25608 obo:IAO_0000115 "A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates." ; oboInOwl:hasDbXref "KEGG:C01329" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NMP", "Nucleoside monophosphate", "nucleoside phosphates" ; oboInOwl:id "CHEBI:25608" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside phosphate" ; rdfs:subClassOf obo:CHEBI_25703, obo:CHEBI_37734, obo:CHEBI_61120, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33838 ] . obo:CHEBI_25676 obo:IAO_0000115 "A peptide containing a relatively small number of amino acids." ; oboInOwl:hasAlternativeId "CHEBI:7755" ; oboInOwl:hasDbXref "Wikipedia:Oligopeptide" ; oboInOwl:hasExactSynonym "oligopeptides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Oligopeptid", "oligopeptido" ; oboInOwl:id "CHEBI:25676" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oligopeptide" ; rdfs:subClassOf obo:CHEBI_16670 . obo:CHEBI_25693 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic heteromonocyclic compounds" ; oboInOwl:id "CHEBI:25693" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic heteromonocyclic compound" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_33670 . obo:CHEBI_25696 obo:IAO_0000115 "Any organic ion with a net negative charge." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic anions" ; oboInOwl:id "CHEBI:25696" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic anion" ; rdfs:subClassOf obo:CHEBI_22563, obo:CHEBI_25699 . obo:CHEBI_25697 obo:IAO_0000115 "Any organic ion with a net positive charge." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic cations" ; oboInOwl:id "CHEBI:25697" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic cation" ; rdfs:subClassOf obo:CHEBI_25699, obo:CHEBI_36916 . obo:CHEBI_25698 obo:IAO_0000115 "An organooxygen compound with formula ROR, where R is not hydrogen." ; chebi:charge "0" ; chebi:formula "OR2" ; chebi:mass "15.99940" ; chebi:monoisotopicmass "15.99491" ; chebi:smiles "[*]O[*]" ; oboInOwl:hasExactSynonym "ether", "ethers" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ethers" ; oboInOwl:id "CHEBI:25698" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ether" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_25699 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic ions" ; oboInOwl:id "CHEBI:25699" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic ion" ; rdfs:subClassOf obo:CHEBI_24870, obo:CHEBI_50860 . obo:CHEBI_25701 obo:IAO_0000115 "An oxide in which the oxygen atom is bonded to a carbon atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic oxides" ; oboInOwl:id "CHEBI:25701" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic oxide" ; rdfs:subClassOf obo:CHEBI_25741, obo:CHEBI_72695 . obo:CHEBI_25703 oboInOwl:hasDbXref "Wikipedia:Organophosphate" ; oboInOwl:hasExactSynonym "organic phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic phosphate ester", "organic phosphate esters", "organic phosphates", "organophosphate ester", "organophosphate esters" ; oboInOwl:id "CHEBI:25703" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic phosphate" ; rdfs:subClassOf obo:CHEBI_25710, obo:CHEBI_26020 . obo:CHEBI_2571 obo:IAO_0000115 "An alcohol derived from an aliphatic compound." ; chebi:charge "0" ; chebi:formula "HOR" ; chebi:mass "17.007" ; chebi:monoisotopicmass "17.00274" ; chebi:smiles "O*" ; oboInOwl:hasDbXref "KEGG:C02525" ; oboInOwl:hasExactSynonym "Aliphatic alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aliphatic alcohols", "an aliphatic alcohol" ; oboInOwl:id "CHEBI:2571" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aliphatic alcohol" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_25710 obo:IAO_0000115 "An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters." ; oboInOwl:hasDbXref "Wikipedia:Organophosphorus_compound" ; oboInOwl:hasExactSynonym "organophosphorus compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organophosphorus compounds" ; oboInOwl:id "CHEBI:25710" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organophosphorus compound" ; rdfs:subClassOf obo:CHEBI_26082, obo:CHEBI_33285 . obo:CHEBI_25728 obo:IAO_0000115 "A solute used by a cell under water stress to maintain cell volume." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "osmolytes" ; oboInOwl:id "CHEBI:25728" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "osmolyte" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_25741 obo:IAO_0000115 "An oxide is a chemical compound of oxygen with other chemical elements." ; oboInOwl:hasExactSynonym "oxide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxides" ; oboInOwl:id "CHEBI:25741" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxide" ; rdfs:subClassOf obo:CHEBI_25806, obo:CHEBI_37577 . obo:CHEBI_25750 obo:IAO_0000115 "Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes." ; chebi:charge "0" ; chebi:formula "CHNOR2" ; chebi:mass "43.02470" ; chebi:monoisotopicmass "43.00581" ; chebi:smiles "O\\N=C(\\[*])[*]" ; oboInOwl:hasExactSynonym "oxime", "oximes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oximes" ; oboInOwl:id "CHEBI:25750" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxime" ; rdfs:subClassOf obo:CHEBI_50860, obo:CHEBI_51143, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_142513 ] . obo:CHEBI_2580 obo:IAO_0000115 "Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:2580" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "unsaturated fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_27208 ] . obo:CHEBI_25805 chebi:charge "0" ; chebi:formula "O" ; chebi:inchi "InChI=1S/O" ; chebi:inchikey "QVGXLLKOCUKJST-UHFFFAOYSA-N" ; chebi:mass "15.99940" ; chebi:monoisotopicmass "15.99491" ; chebi:smiles "[O]" ; oboInOwl:hasDbXref "KEGG:C00007", "WebElements:O" ; oboInOwl:hasExactSynonym "oxygen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "8O", "O", "Sauerstoff", "oxigeno", "oxygen", "oxygene" ; oboInOwl:id "CHEBI:25805" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxygen atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25585, obo:CHEBI_33303, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_25806 oboInOwl:hasExactSynonym "oxygen molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxygen molecular entities" ; oboInOwl:id "CHEBI:25806" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxygen molecular entity" ; rdfs:subClassOf obo:CHEBI_33304, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_25805 ] . obo:CHEBI_25810 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxopurines" ; oboInOwl:id "CHEBI:25810" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxopurine" ; rdfs:subClassOf obo:CHEBI_26401 . obo:CHEBI_25897 obo:IAO_0000115 "Any C5, straight-chain, monounsaturated fatty acid." ; chebi:charge "0" ; chebi:formula "C5H8O2" ; chebi:mass "100.116" ; chebi:monoisotopicmass "100.05243" ; oboInOwl:hasExactSynonym "pentenoic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C5:1", "pentenoic acids" ; oboInOwl:id "CHEBI:25897" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pentenoic acid" ; rdfs:subClassOf obo:CHEBI_25413, obo:CHEBI_26666, obo:CHEBI_59202 . obo:CHEBI_25900 oboInOwl:hasExactSynonym "aldopentose phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldopentose phosphates" ; oboInOwl:id "CHEBI:25900" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aldopentose phosphate" ; rdfs:subClassOf obo:CHEBI_35131, obo:CHEBI_84055 . obo:CHEBI_25901 obo:IAO_0000115 "A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose)." ; oboInOwl:hasExactSynonym "pentose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pentoses" ; oboInOwl:id "CHEBI:25901" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pentose" ; rdfs:subClassOf obo:CHEBI_35381 . obo:CHEBI_25940 obo:IAO_0000115 "Compounds of structure ROOR'." ; chebi:charge "0" ; chebi:formula "O2R2" ; chebi:mass "31.999" ; chebi:monoisotopicmass "31.98983" ; chebi:smiles "[*]OO[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a peroxide" ; oboInOwl:id "CHEBI:25940" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "peroxides" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25741, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29369 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63248 ] . obo:CHEBI_25944 obo:IAO_0000115 "Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests." ; oboInOwl:hasDbXref "Wikipedia:Pesticide" ; oboInOwl:hasExactSynonym "pesticide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Pestizid", "Pestizide", "pesticides" ; oboInOwl:id "CHEBI:25944" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pesticide" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_25990 obo:IAO_0000115 "An ethanolamine compound having a phenyl (substituted or unsubstituted) group on the carbon bearing the hydroxy substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:25990" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phenylethanolamines" ; rdfs:subClassOf obo:CHEBI_23981 . obo:CHEBI_26020 obo:IAO_0000115 "Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom." ; oboInOwl:hasExactSynonym "phosphates" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "phosphates" ; oboInOwl:id "CHEBI:26020" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphate" ; rdfs:subClassOf obo:CHEBI_26079 . obo:CHEBI_26034 obo:IAO_0000115 "A phosphatidylinositol monophosphate carrying the phosphate group at the 3-position." ; oboInOwl:hasDbXref "PMID:18927492" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "PI(3)P", "PtdIns3P", "phosphatidylinositol 3-phosphates" ; oboInOwl:id "CHEBI:26034" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphatidylinositol 3-phosphate" ; rdfs:subClassOf obo:CHEBI_26036 . obo:CHEBI_26036 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "phosphatidylinositol monophosphates" ; oboInOwl:id "CHEBI:26036" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphatidylinositol monophosphate" ; rdfs:subClassOf obo:CHEBI_28765 . obo:CHEBI_26078 obo:IAO_0000115 "A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom." ; chebi:charge "0" ; chebi:formula "H3O4P" ; chebi:inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)" ; chebi:inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-N" ; chebi:mass "97.99520" ; chebi:monoisotopicmass "97.97690" ; chebi:smiles "[H]OP(=O)(O[H])O[H]" ; oboInOwl:hasDbXref "Beilstein:1921286", "CAS:7664-38-2", "Drug_Central:4478", "Gmelin:2000", "HMDB:HMDB0002142", "KEGG:C00009", "KEGG:D05467", "KNApSAcK:C00007408", "PMID:11455380", "PMID:15630224", "PMID:17439666", "PMID:17518491", "PMID:22282755", "PMID:22333268", "PMID:22381614", "PMID:22401268", "Reaxys:1921286", "Wikipedia:Phosphoric_Acid" ; oboInOwl:hasExactSynonym "Phosphoric acid", "phosphoric acid", "tetraoxophosphoric acid", "trihydrogen tetraoxophosphate(3-)", "trihydroxidooxidophosphorus" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H3PO4", "Orthophosphoric acid", "Phosphate", "Phosphorsaeure", "Phosphorsaeureloesungen", "[PO(OH)3]", "acide phosphorique", "acidum phosphoricum", "orthophosphoric acid" ; oboInOwl:id "CHEBI:26078" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphoric acid" ; rdfs:subClassOf obo:CHEBI_59698, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33287 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84735 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_39745 ] . obo:CHEBI_26079 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26079" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "phosphoric acid derivative" ; rdfs:subClassOf obo:CHEBI_36359, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_26078 ] . obo:CHEBI_26082 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "phosphorus molecular entities" ; oboInOwl:id "CHEBI:26082" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphorus molecular entity" ; rdfs:subClassOf obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_28659 ] . obo:CHEBI_26144 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26144" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "piperazines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_26151 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26151" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "piperidines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_26167 obo:IAO_0000115 "Any amino acid whose side chain is capable of forming one or more hydrogen bonds." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "OC(C(*)N)=O" ; oboInOwl:hasAlternativeId "CHEBI:8283" ; oboInOwl:hasDbXref "MetaCyc:Polar-amino-acids", "PMID:12016058" ; oboInOwl:hasExactSynonym "polar amino acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polar amino acids", "polar amino-acid", "polar amino-acids" ; oboInOwl:id "CHEBI:26167" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polar amino acid" ; rdfs:subClassOf obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_62031 ] . obo:CHEBI_26188 obo:IAO_0000115 "Natural and synthetic compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides." ; oboInOwl:hasExactSynonym "polyketide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyketides" ; oboInOwl:id "CHEBI:26188" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polyketide" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_26191 obo:IAO_0000115 "A compound that contains two or more hydroxy groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyols" ; oboInOwl:id "CHEBI:26191" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polyol" ; rdfs:subClassOf obo:CHEBI_33822 . obo:CHEBI_26214 obo:IAO_0000115 "Natural pigments containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure." ; oboInOwl:hasDbXref "Wikipedia:Porphyrin" ; oboInOwl:hasExactSynonym "porphyrins" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26214" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "porphyrins" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_36309, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ] . obo:CHEBI_26216 chebi:charge "0" ; chebi:formula "K" ; chebi:inchi "InChI=1S/K" ; chebi:inchikey "ZLMJMSJWJFRBEC-UHFFFAOYSA-N" ; chebi:mass "39.09830" ; chebi:monoisotopicmass "38.96371" ; chebi:smiles "[K]" ; oboInOwl:hasDbXref "CAS:7440-09-7", "DrugBank:DB01345", "KEGG:C00238", "WebElements:K" ; oboInOwl:hasExactSynonym "potassium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "19K", "K", "Kalium", "kalium", "potasio", "potassium" ; oboInOwl:id "CHEBI:26216" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "potassium atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_22314, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ] . obo:CHEBI_26292 obo:IAO_0000115 "A ketone that is propane carrying at least one oxo substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26292" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "propanones" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_26348 obo:IAO_0000115 "A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity." ; oboInOwl:hasExactSynonym "prosthetic group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "groupe prosthetique", "prosthetic groups" ; oboInOwl:id "CHEBI:26348" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "prosthetic group" ; rdfs:subClassOf obo:CHEBI_23357 . obo:CHEBI_26385 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine alkaloids" ; oboInOwl:id "CHEBI:26385" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine alkaloid" ; rdfs:subClassOf obo:CHEBI_22315, obo:CHEBI_26401 . obo:CHEBI_26386 obo:IAO_0000115 "A nucleobase whose skeleton is derived from purine." ; chebi:charge "0" ; chebi:formula "C5H3N4R2" ; chebi:mass "119.104" ; chebi:monoisotopicmass "119.03577" ; chebi:smiles "C1(NC(=NC=2NC=NC12)*)=*" ; oboInOwl:hasDbXref "KEGG:C15587" ; oboInOwl:hasExactSynonym "purine nucleobase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a purine nucleobase", "purine bases", "purine nucleobases" ; oboInOwl:id "CHEBI:26386" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine nucleobase" ; rdfs:subClassOf obo:CHEBI_18282, obo:CHEBI_26401 . obo:CHEBI_26393 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine nucleoside triphosphates" ; oboInOwl:id "CHEBI:26393" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine nucleoside triphosphate" ; rdfs:subClassOf obo:CHEBI_17326 . obo:CHEBI_26394 oboInOwl:hasExactSynonym "purine nucleoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine nucleosides" ; oboInOwl:id "CHEBI:26394" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine nucleoside" ; rdfs:subClassOf obo:CHEBI_26401, obo:CHEBI_33838 . obo:CHEBI_26395 obo:IAO_0000115 "Any nucleotide that has a purine nucleobase." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine nucleotides" ; oboInOwl:id "CHEBI:26395" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine nucleotide" ; rdfs:subClassOf obo:CHEBI_26401, obo:CHEBI_36976 . obo:CHEBI_26398 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine ribonucleoside triphosphates" ; oboInOwl:id "CHEBI:26398" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine ribonucleoside triphosphate" ; rdfs:subClassOf obo:CHEBI_17972, obo:CHEBI_26393 . obo:CHEBI_26399 obo:IAO_0000115 "A ribonucleoside that has a purine moiety as the nucleobase (the R group in the illustration)." ; chebi:charge "0" ; chebi:formula "C5H9O4R" ; chebi:mass "133.123" ; chebi:monoisotopicmass "133.05008" ; chebi:smiles "*[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine ribonucleosides" ; oboInOwl:id "CHEBI:26399" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine ribonucleoside" ; rdfs:subClassOf obo:CHEBI_18254, obo:CHEBI_26394 . obo:CHEBI_26400 obo:IAO_0000115 "Any ribonucleotide that has a purine nucleobase." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine ribonucleotides" ; oboInOwl:id "CHEBI:26400" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine ribonucleotide" ; rdfs:subClassOf obo:CHEBI_26395, obo:CHEBI_26561 . obo:CHEBI_26401 obo:IAO_0000115 "A class of imidazopyrimidines that consists of purine and its substituted derivatives." ; chebi:charge "0" ; chebi:formula "C5N4R7" ; chebi:mass "116.080" ; chebi:monoisotopicmass "116.01230" ; oboInOwl:hasAlternativeId "CHEBI:13678" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26401" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purines" ; rdfs:subClassOf obo:CHEBI_35875 . obo:CHEBI_26416 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyridine alkaloids" ; oboInOwl:id "CHEBI:26416" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyridine alkaloid" ; rdfs:subClassOf obo:CHEBI_22315, obo:CHEBI_26421 . obo:CHEBI_26421 obo:IAO_0000115 "Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26421" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyridines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_26432 obo:IAO_0000115 "A nucleobase whose skeleton is derived from pyrimidine." ; chebi:charge "0" ; chebi:formula "C4HN2R4" ; chebi:mass "77.064" ; chebi:monoisotopicmass "77.01397" ; chebi:smiles "N1C(=C(C(=NC1=*)*)*)*" ; oboInOwl:hasExactSynonym "pyrimidine nucleobase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a pyrimidine nucleobase", "pyrimidine bases", "pyrimidine nucleobases" ; oboInOwl:id "CHEBI:26432" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyrimidine nucleobase" ; rdfs:subClassOf obo:CHEBI_18282, obo:CHEBI_39447 . obo:CHEBI_26456 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyrrolidine alkaloids" ; oboInOwl:id "CHEBI:26456" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyrrolidine alkaloid" ; rdfs:subClassOf obo:CHEBI_22315, obo:CHEBI_38260 . obo:CHEBI_26469 obo:IAO_0000115 "A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26469" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "quaternary nitrogen compound" ; rdfs:subClassOf obo:CHEBI_35352, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_35267 ] . obo:CHEBI_26509 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "quinoline alkaloids" ; oboInOwl:id "CHEBI:26509" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "quinoline alkaloid" ; rdfs:subClassOf obo:CHEBI_22315 . obo:CHEBI_26513 obo:IAO_0000115 "A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26513" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "quinolines" ; rdfs:subClassOf obo:CHEBI_33659, obo:CHEBI_38101 . obo:CHEBI_26523 obo:IAO_0000115 "Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers." ; oboInOwl:hasDbXref "Wikipedia:Reactive_oxygen_species" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ROS" ; oboInOwl:id "CHEBI:26523" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "reactive oxygen species" ; rdfs:subClassOf obo:CHEBI_25806 . obo:CHEBI_26547 oboInOwl:hasExactSynonym "rhamnoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "rhamnosides" ; oboInOwl:id "CHEBI:26547" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "rhamnoside" ; rdfs:subClassOf obo:CHEBI_35315 . obo:CHEBI_26561 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleotides" ; oboInOwl:id "CHEBI:26561" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribonucleotide" ; rdfs:subClassOf obo:CHEBI_26562, obo:CHEBI_36976 . obo:CHEBI_26562 oboInOwl:hasExactSynonym "ribose phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribose phosphates" ; oboInOwl:id "CHEBI:26562" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribose phosphate" ; rdfs:subClassOf obo:CHEBI_25900 . obo:CHEBI_26607 obo:IAO_0000115 "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess." ; oboInOwl:hasDbXref "PMID:16492686", "PMID:19763019", "PMID:20237329" ; oboInOwl:hasExactSynonym "saturated fatty acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SFA", "SFAs", "saturated fatty acids" ; oboInOwl:id "CHEBI:26607" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "saturated fatty acid" ; rdfs:subClassOf obo:CHEBI_35366 . obo:CHEBI_26650 obo:IAO_0000115 "An L-alpha-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class." ; oboInOwl:hasDbXref "PMID:20709681" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3-phosphoglycerate family amino acid", "3-phosphoglycerate family amino acids", "serine family amino acids" ; oboInOwl:id "CHEBI:26650" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "serine family amino acid" ; rdfs:subClassOf obo:CHEBI_15705, obo:CHEBI_83813 . obo:CHEBI_26666 obo:IAO_0000115 "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid." ; chebi:charge "0" ; chebi:formula "CH2OR" ; chebi:mass "45.017" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "OC([*])=O" ; oboInOwl:hasDbXref "PMID:16633129", "PMID:16870803", "PMID:18203540", "PMID:20148677" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SCFA", "SCFAs", "short-chain fatty acids" ; oboInOwl:id "CHEBI:26666" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "short-chain fatty acid" ; rdfs:subClassOf obo:CHEBI_35366, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58951 ] . obo:CHEBI_26708 chebi:charge "0" ; chebi:formula "Na" ; chebi:inchi "InChI=1S/Na" ; chebi:inchikey "KEAYESYHFKHZAL-UHFFFAOYSA-N" ; chebi:mass "22.98977" ; chebi:monoisotopicmass "22.98977" ; chebi:smiles "[Na]" ; oboInOwl:hasDbXref "CAS:7440-23-5", "Gmelin:16221", "KEGG:C01330", "WebElements:Na" ; oboInOwl:hasExactSynonym "sodium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "11Na", "Na", "Natrium", "natrium", "sodio", "sodium" ; oboInOwl:id "CHEBI:26708" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sodium atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_22314, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ] . obo:CHEBI_26710 obo:IAO_0000115 "An inorganic chloride salt having sodium(1+) as the counterion." ; chebi:charge "0" ; chebi:formula "ClNa" ; chebi:inchi "InChI=1S/ClH.Na/h1H;/q;+1/p-1" ; chebi:inchikey "FAPWRFPIFSIZLT-UHFFFAOYSA-M" ; chebi:mass "58.44247" ; chebi:monoisotopicmass "57.95862" ; chebi:smiles "[Na+].[Cl-]" ; oboInOwl:hasDbXref "Beilstein:3534976", "CAS:7647-14-5", "Gmelin:13673", "KEGG:C13563", "KEGG:D02056", "MetaCyc:NACL", "PPDB:595", "Reaxys:3534976", "Wikipedia:Sodium_Chloride" ; oboInOwl:hasExactSynonym "sodium chloride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kochsalz", "NaCl", "Natriumchlorid", "chlorure de sodium", "cloruro sodico", "common salt", "halite", "natrii chloridum", "rock salt", "salt", "table salt" ; oboInOwl:id "CHEBI:26710" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sodium chloride" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_36093, obo:CHEBI_38702, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149552 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_79314 ] . obo:CHEBI_26712 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sodium compounds", "sodium molecular entities" ; oboInOwl:id "CHEBI:26712" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sodium molecular entity" ; rdfs:subClassOf obo:CHEBI_33296, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_26708 ] . obo:CHEBI_26714 obo:IAO_0000115 "Any alkali metal salt having sodium(1+) as the cation." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Natriumsalz", "Natriumsalze", "sodium salts" ; oboInOwl:id "CHEBI:26714" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sodium salt" ; rdfs:subClassOf obo:CHEBI_26712, obo:CHEBI_35479, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29101 ] . obo:CHEBI_26764 obo:IAO_0000115 "Any steroid that acts as hormone." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Steroidhormon", "Steroidhormone", "hormona esteroide", "hormonas esteroideas", "hormone steroide", "hormones steroides", "steroid hormones" ; oboInOwl:id "CHEBI:26764" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "steroid hormone" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35341, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24621 ] . obo:CHEBI_26766 oboInOwl:hasDbXref "KEGG:C15507" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "steroid lactones" ; oboInOwl:id "CHEBI:26766" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "steroid lactone" ; rdfs:subClassOf obo:CHEBI_25000, obo:CHEBI_35341 . obo:CHEBI_26816 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrate phosphates" ; oboInOwl:id "CHEBI:26816" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbohydrate phosphate" ; rdfs:subClassOf obo:CHEBI_25703, obo:CHEBI_37734, obo:CHEBI_63299 . obo:CHEBI_26822 obo:IAO_0000115 "Any sulfur molecular entity that involves either covalently bonded or anionic sulfur." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulphides" ; oboInOwl:id "CHEBI:26822" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfide" ; rdfs:subClassOf obo:CHEBI_26835 . obo:CHEBI_26830 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26830" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "sulfonium compound" ; rdfs:subClassOf obo:CHEBI_26835 . obo:CHEBI_26833 chebi:charge "0" ; chebi:formula "S" ; chebi:inchi "InChI=1S/S" ; chebi:inchikey "NINIDFKCEFEMDL-UHFFFAOYSA-N" ; chebi:mass "32.06600" ; chebi:monoisotopicmass "31.97207" ; chebi:smiles "[S]" ; oboInOwl:hasDbXref "CAS:7704-34-9", "KEGG:C00087", "KEGG:D06527", "PPDB:605", "WebElements:S" ; oboInOwl:hasExactSynonym "sulfur" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "16S", "Elemental sulfur", "S", "Schwefel", "azufre", "soufre", "sulfur", "sulphur", "theion" ; oboInOwl:id "CHEBI:26833" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25585, obo:CHEBI_33303, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_26834 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfur-containing amino acids" ; oboInOwl:id "CHEBI:26834" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur-containing amino acid" ; rdfs:subClassOf obo:CHEBI_33576, obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_63470 ] . obo:CHEBI_26835 oboInOwl:hasExactSynonym "sulfur molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfur molecular entities" ; oboInOwl:id "CHEBI:26835" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur molecular entity" ; rdfs:subClassOf obo:CHEBI_33304, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_26833 ] . obo:CHEBI_26873 obo:IAO_0000115 "Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group." ; oboInOwl:hasDbXref "Wikipedia:Terpenoid" ; oboInOwl:hasExactSynonym "Terpenoid", "terpenoids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "terpenoide", "terpenoides" ; oboInOwl:id "CHEBI:26873" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "terpenoid" ; rdfs:subClassOf obo:CHEBI_24913, [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_35186 ] . obo:CHEBI_26878 obo:IAO_0000115 "A tertiary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it." ; chebi:charge "0" ; chebi:formula "C4H7OR3" ; chebi:mass "71.09780" ; chebi:monoisotopicmass "71.04969" ; chebi:smiles "OC(C[*])(C[*])C[*]" ; oboInOwl:hasExactSynonym "tertiary alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tertiary alcohols" ; oboInOwl:id "CHEBI:26878" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tertiary alcohol" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_26912 obo:IAO_0000115 "Any oxacycle having an oxolane (tetrahydrofuran) skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:26912" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxolanes" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38104 . obo:CHEBI_26921 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tetrahydropyridines" ; oboInOwl:id "CHEBI:26921" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tetrahydropyridine" ; rdfs:subClassOf obo:CHEBI_26421 . obo:CHEBI_26932 obo:IAO_0000115 "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next." ; oboInOwl:hasExactSynonym "tetrapyrrole", "tetrapyrroles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a tetrapyrrole" ; oboInOwl:id "CHEBI:26932" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tetrapyrrole" ; rdfs:subClassOf obo:CHEBI_33833, obo:CHEBI_38077 . obo:CHEBI_26952 oboInOwl:hasDbXref "KEGG:C01857" ; oboInOwl:hasExactSynonym "ethanethioic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Thioessigsaeure" ; oboInOwl:id "CHEBI:26952" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "thioacetic acid" ; rdfs:subClassOf obo:CHEBI_35737, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30320 ] . obo:CHEBI_26959 obo:IAO_0000115 "An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "thiocarboxylic esters" ; oboInOwl:id "CHEBI:26959" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "thiocarboxylic ester" ; rdfs:subClassOf obo:CHEBI_33261, obo:CHEBI_35701 . obo:CHEBI_26979 obo:IAO_0000115 "An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterotricyclic compounds", "organic heterotricyclic compounds" ; oboInOwl:id "CHEBI:26979" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic heterotricyclic compound" ; rdfs:subClassOf obo:CHEBI_36688, obo:CHEBI_38166, obo:CHEBI_51959 . obo:CHEBI_27026 obo:IAO_0000115 "Poisonous substance produced by a biological organism such as a microbe, animal or plant." ; oboInOwl:hasDbXref "Wikipedia:Toxin" ; oboInOwl:hasExactSynonym "toxin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "toxins" ; oboInOwl:id "CHEBI:27026" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "toxin" ; rdfs:subClassOf obo:CHEBI_25212, obo:CHEBI_64909 . obo:CHEBI_27027 obo:IAO_0000115 "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions." ; oboInOwl:hasDbXref "Wikipedia:Micronutrient" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "micronutrients", "trace elements" ; oboInOwl:id "CHEBI:27027" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "micronutrient" ; rdfs:subClassOf obo:CHEBI_33284 . obo:CHEBI_27081 obo:IAO_0000115 "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell." ; oboInOwl:hasExactSynonym "transition element" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Uebergangselement", "Uebergangsmetalle", "metal de transicion", "metal de transition", "metales de transicion", "metaux de transition", "transition element", "transition elements", "transition metal", "transition metals" ; oboInOwl:id "CHEBI:27081" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "transition element atom" ; rdfs:subClassOf obo:CHEBI_33521 . obo:CHEBI_27134 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "trimethylxanthines" ; oboInOwl:id "CHEBI:27134" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "trimethylxanthine" ; rdfs:subClassOf obo:CHEBI_25348 . obo:CHEBI_27136 obo:IAO_0000115 "A chemical compound containing three hydroxy groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "triols" ; oboInOwl:id "CHEBI:27136" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "triol" ; rdfs:subClassOf obo:CHEBI_26191 . obo:CHEBI_27162 obo:IAO_0000115 "Tryptamine and its substitution derivatives." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:27162" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tryptamines" ; rdfs:subClassOf obo:CHEBI_24828 . obo:CHEBI_27171 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterobicyclic compounds", "organic heterobicyclic compounds" ; oboInOwl:id "CHEBI:27171" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic heterobicyclic compound" ; rdfs:subClassOf obo:CHEBI_33672, obo:CHEBI_38166 . obo:CHEBI_27175 obo:IAO_0000115 "Aralkylamino compounds which contain a tyramine skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:27175" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tyramines" ; rdfs:subClassOf obo:CHEBI_33853, obo:CHEBI_64365 . obo:CHEBI_27207 obo:IAO_0000115 "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "univalent acyl group", "univalent carboacyl groups", "univalent carboxylic acyl groups" ; oboInOwl:id "CHEBI:27207" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "univalent carboacyl group" ; rdfs:subClassOf obo:CHEBI_37838 . obo:CHEBI_27208 obo:IAO_0000115 "Any fatty acid containing at least one C=C or C#C bond." ; oboInOwl:hasDbXref "LIPID_MAPS_class:LMFA0103", "PMID:5322381" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkene acid", "olefinic acid", "unsaturated fatty acids" ; oboInOwl:id "CHEBI:27208" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "unsaturated fatty acid" ; rdfs:subClassOf obo:CHEBI_35366, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_2580 ] . obo:CHEBI_27363 chebi:charge "0" ; chebi:formula "Zn" ; chebi:inchi "InChI=1S/Zn" ; chebi:inchikey "HCHKCACWOHOZIP-UHFFFAOYSA-N" ; chebi:mass "65.39000" ; chebi:monoisotopicmass "63.92914" ; chebi:smiles "[Zn]" ; oboInOwl:hasDbXref "CAS:7440-66-6", "Gmelin:16321", "KEGG:C00038", "PDBeChem:ZN", "WebElements:Zn" ; oboInOwl:hasExactSynonym "zinc" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "30Zn", "Zink", "Zn", "Zn(II)", "Zn2+", "cinc", "zinc", "zincum" ; oboInOwl:id "CHEBI:27363" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "zinc atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33340, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_27364 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "zinc compounds", "zinc molecular entities" ; oboInOwl:id "CHEBI:27364" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "zinc molecular entity" ; rdfs:subClassOf obo:CHEBI_33673, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_27363 ] . obo:CHEBI_27369 obo:IAO_0000115 "A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer)." ; oboInOwl:hasExactSynonym "zwitterion", "zwitterions" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "compose zwitterionique", "compuestos zwitterionicos", "zwitteriones", "zwitterionic compounds" ; oboInOwl:id "CHEBI:27369" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "zwitterion" ; rdfs:subClassOf obo:CHEBI_51151 . obo:CHEBI_27376 obo:IAO_0000115 "An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl." ; chebi:charge "0" ; chebi:formula "CH4O3S" ; chebi:inchi "InChI=1S/CH4O3S/c1-5(2,3)4/h1H3,(H,2,3,4)" ; chebi:inchikey "AFVFQIVMOAPDHO-UHFFFAOYSA-N" ; chebi:mass "96.10666" ; chebi:monoisotopicmass "95.98812" ; chebi:smiles "CS(O)(=O)=O" ; oboInOwl:hasAlternativeId "CHEBI:6813" ; oboInOwl:hasDbXref "Beilstein:1446024", "CAS:75-75-2", "Gmelin:1681", "KEGG:C11145", "MetaCyc:CPD-3746", "PMID:24304088", "PMID:24593036", "Reaxys:1446024", "Wikipedia:Methanesulfonic_acid" ; oboInOwl:hasExactSynonym "Methanesulfonic acid", "methanesulfonic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Methansulfonsaeure", "methylsulfonic acid" ; oboInOwl:id "CHEBI:27376" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methanesulfonic acid" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_47901, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_25224 ] . obo:CHEBI_27563 chebi:charge "0" ; chebi:formula "As" ; chebi:inchi "InChI=1S/As" ; chebi:inchikey "RQNWIZPPADIBDY-UHFFFAOYSA-N" ; chebi:mass "74.92160" ; chebi:monoisotopicmass "74.92159" ; chebi:smiles "[As]" ; oboInOwl:hasAlternativeId "CHEBI:22630", "CHEBI:2845" ; oboInOwl:hasDbXref "CAS:7440-38-2", "KEGG:C06269", "WebElements:As" ; oboInOwl:hasExactSynonym "arsenic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "33As", "Arsen", "Arsenic", "As", "arsenic", "arsenico", "arsenicum" ; oboInOwl:id "CHEBI:27563" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "arsenic atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_137980, obo:CHEBI_33300, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_27594 chebi:charge "0" ; chebi:formula "C" ; chebi:inchi "InChI=1S/C" ; chebi:inchikey "OKTJSMMVPCPJKN-UHFFFAOYSA-N" ; chebi:mass "12.01070" ; chebi:monoisotopicmass "12.00000" ; chebi:smiles "[C]" ; oboInOwl:hasAlternativeId "CHEBI:23009", "CHEBI:3399" ; oboInOwl:hasDbXref "CAS:7440-44-0", "KEGG:C06265", "WebElements:C" ; oboInOwl:hasExactSynonym "carbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "6C", "C", "Carbon", "Kohlenstoff", "carbon", "carbone", "carbonium", "carbono" ; oboInOwl:id "CHEBI:27594" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbon atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25585, obo:CHEBI_33306, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_27638 obo:IAO_0000115 "A cobalt group element atom that has atomic number 27." ; chebi:charge "0" ; chebi:formula "Co" ; chebi:inchi "InChI=1S/Co" ; chebi:inchikey "GUTLYIVDDKVIGB-UHFFFAOYSA-N" ; chebi:mass "58.93320" ; chebi:monoisotopicmass "58.93319" ; chebi:smiles "[Co]" ; oboInOwl:hasAlternativeId "CHEBI:23335", "CHEBI:3788" ; oboInOwl:hasDbXref "CAS:7440-48-4", "KEGG:C00175", "KEGG:C19171", "PDBeChem:3CO", "WebElements:Co" ; oboInOwl:hasExactSynonym "cobalt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "27Co", "Co", "Cobalt", "Kobalt", "cobalt", "cobalto", "cobaltum" ; oboInOwl:id "CHEBI:27638" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cobalt atom" ; rdfs:subClassOf obo:CHEBI_33358, obo:CHEBI_88184, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ] . obo:CHEBI_27682 oboInOwl:hasAlternativeId "CHEBI:1330", "CHEBI:19832" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:27682" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "3',5'-cyclic dGMP" ; rdfs:subClassOf obo:CHEBI_19834 . obo:CHEBI_27732 obo:IAO_0000115 "A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee." ; chebi:charge "0" ; chebi:formula "C8H10N4O2" ; chebi:inchi "InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3" ; chebi:inchikey "RYYVLZVUVIJVGH-UHFFFAOYSA-N" ; chebi:mass "194.19076" ; chebi:monoisotopicmass "194.08038" ; chebi:smiles "Cn1cnc2n(C)c(=O)n(C)c(=O)c12" ; oboInOwl:hasAlternativeId "CHEBI:22982", "CHEBI:3295", "CHEBI:41472" ; oboInOwl:hasDbXref "Beilstein:17705", "CAS:58-08-2", "DrugBank:DB00201", "Drug_Central:463", "Gmelin:103040", "HMDB:HMDB0001847", "KEGG:C07481", "KEGG:D00528", "KNApSAcK:C00001492", "LINCS:LSM-2026", "MetaCyc:1-3-7-TRIMETHYLXANTHINE", "PDBeChem:CFF", "PMID:10510174", "PMID:10796597", "PMID:10803761", "PMID:10822912", "PMID:10884512", "PMID:10924888", "PMID:10983026", "PMID:11014293", "PMID:11022879", "PMID:11209966", "PMID:11312039", "PMID:11410911", "PMID:11431501", "PMID:11815511", "PMID:11949272", "PMID:12397877", "PMID:12457274", "PMID:12574990", "PMID:12915014", "PMID:12943586", "PMID:14521986", "PMID:14607010", "PMID:15257305", "PMID:15280431", "PMID:15681408", "PMID:15718055", "PMID:15840517", "PMID:16143823", "PMID:16391865", "PMID:16528931", "PMID:16644114", "PMID:16709440", "PMID:16805851", "PMID:16856769", "PMID:17132260", "PMID:17387608", "PMID:17508167", "PMID:17724925", "PMID:17932622", "PMID:17957400", "PMID:18068204", "PMID:18258404", "PMID:18421070", "PMID:18513215", "PMID:18625110", "PMID:18647558", "PMID:19007524", "PMID:19047957", "PMID:19084078", "PMID:19088793", "PMID:19418355", "PMID:19879252", "PMID:20164568", "PMID:20470411", "PMID:22114686", "PMID:22770225", "PMID:23551936", "PMID:24039592", "PMID:7441110", "PMID:7689104", "PMID:8332255", "PMID:8347173", "PMID:8679661", "PMID:9063686", "PMID:9067318", "PMID:9132918", "PMID:9218278", "Reaxys:17705", "Wikipedia:Caffeine" ; oboInOwl:hasExactSynonym "1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione", "CAFFEINE", "Caffeine", "caffeine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,3,7-Trimethylxanthine", "1,3,7-trimethyl-2,6-dioxopurine", "1,3,7-trimethylpurine-2,6-dione", "1,3,7-trimethylxanthine", "1-methyltheobromine", "3,7-Dihydro-1,3,7-trimethyl-1H-purin-2,6-dion", "7-methyltheophylline", "Coffein", "Koffein", "Thein", "anhydrous caffeine", "cafeina", "cafeine", "guaranine", "mateina", "methyltheobromine", "teina", "theine" ; oboInOwl:id "CHEBI:27732" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "caffeine" ; rdfs:subClassOf obo:CHEBI_27134, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25435 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35337 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35471 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35498 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50218 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50925 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_53121 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_60809 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64047 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_67114 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76946 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_85234 ] . obo:CHEBI_27780 obo:IAO_0000115 "A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions." ; oboInOwl:hasAlternativeId "CHEBI:23648", "CHEBI:4456" ; oboInOwl:hasDbXref "KEGG:C01689" ; oboInOwl:hasExactSynonym "detergent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Detergents" ; oboInOwl:id "CHEBI:27780" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "detergent" ; rdfs:subClassOf obo:CHEBI_33232, obo:CHEBI_35195 . obo:CHEBI_27848 chebi:charge "0" ; chebi:formula "C6H11O5R" ; chebi:mass "163.14850" ; chebi:monoisotopicmass "163.06065" ; chebi:smiles "C[C@@H]1O[C@@H](O[*])[C@H](O)[C@H](O)[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:10294", "CHEBI:22426" ; oboInOwl:hasDbXref "KEGG:C02757" ; oboInOwl:hasExactSynonym "6-deoxy-alpha-L-mannopyranoside", "alpha-L-Rhamnoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-L-rhamnosides" ; oboInOwl:id "CHEBI:27848" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-L-rhamnoside" ; rdfs:subClassOf obo:CHEBI_26547 . obo:CHEBI_27882 obo:IAO_0000115 "A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions." ; chebi:charge "0" ; chebi:formula "C22H25NO6" ; chebi:inchi "InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1" ; chebi:inchikey "IAKHMKGGTNLKSZ-INIZCTEOSA-N" ; chebi:mass "399.443" ; chebi:monoisotopicmass "399.16819" ; chebi:smiles "COC1=CC2=C(C(OC)=C1OC)C1=CC=C(OC)C(=O)C=C1[C@H](CC2)NC(C)=O" ; oboInOwl:hasAlternativeId "CHEBI:3811" ; oboInOwl:hasDbXref "Beilstein:2228813", "CAS:64-86-8", "Chemspider:5933", "DrugBank:DB01394", "Drug_Central:726", "KEGG:C07592", "KEGG:D00570", "KNApSAcK:C00002327", "LINCS:LSM-5199", "MetaCyc:CPD-9785", "PDBeChem:LOC", "PMID:16188942", "PMID:17619668", "PMID:18787557", "PMID:24530796", "PMID:28832953", "PMID:28912485", "PMID:28959419", "PMID:30565859", "PMID:32025680", "PMID:32426001", "PMID:32511763", "PMID:32837853", "PMID:32865380", "PMID:33100196", "PMID:33166069", "Wikipedia:Colchicine" ; oboInOwl:hasExactSynonym "N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-colchicine", "(S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide", "7alphaH-colchicine", "Colchicin", "Colchicine", "Colchisol", "Colcin", "Colcrys", "Colsaloid", "Condylon", "Goutnil", "Kolkicin", "Mitigare", "colchicina", "colchicinum" ; oboInOwl:id "CHEBI:27882" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(S)-colchicine" ; rdfs:subClassOf obo:CHEBI_23359, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25435 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35845 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_67079 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_51074 ] . obo:CHEBI_28024 chebi:charge "0" ; chebi:formula "CHNO" ; chebi:inchi "InChI=1S/CHNO/c2-1-3/h3H" ; chebi:inchikey "XLJMAIOERFSOGZ-UHFFFAOYSA-N" ; chebi:mass "43.025" ; chebi:monoisotopicmass "43.00581" ; chebi:smiles "OC#N" ; oboInOwl:hasAlternativeId "CHEBI:23422", "CHEBI:3968" ; oboInOwl:hasDbXref "Beilstein:1732479", "CAS:420-05-3", "Chemspider:525", "Gmelin:839", "KEGG:C01417", "PDBeChem:0NM", "PMID:12573832", "PMID:12590561", "PMID:16743625", "PMID:16744204", "PMID:19624192", "PMID:20261791", "PMID:20261792", "PMID:20340793", "PMID:237898", "PMID:4368066", "PMID:6493050" ; oboInOwl:hasExactSynonym "Cyanic acid", "hydrogen nitridooxocarbonate", "hydroxidonitridocarbon", "nitridooxocarbonic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cyansaeure", "HOCN", "Zyansaeure", "[C(N)OH]", "acide cyanique", "acido cianico", "acidum cyanicum" ; oboInOwl:id "CHEBI:28024" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyanic acid" ; rdfs:subClassOf obo:CHEBI_23423, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29195 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_29202 ] . obo:CHEBI_28087 obo:IAO_0000115 "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues." ; oboInOwl:hasAlternativeId "CHEBI:24379", "CHEBI:5466" ; oboInOwl:hasDbXref "CAS:9005-79-2", "GlyGen:G99991IU", "GlyTouCan:G99991IU", "HMDB:HMDB0000757", "KEGG:C00182", "MetaCyc:CPD0-971", "Wikipedia:Glycogen" ; oboInOwl:hasExactSynonym "Glycogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1", "animal starch", "liver starch" ; oboInOwl:id "CHEBI:28087" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glycogen" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_24384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_28112 obo:IAO_0000115 "Chemical element (nickel group element atom) with atomic number 28." ; chebi:charge "0" ; chebi:formula "Ni" ; chebi:inchi "InChI=1S/Ni" ; chebi:inchikey "PXHVJJICTQNCMI-UHFFFAOYSA-N" ; chebi:mass "58.69340" ; chebi:monoisotopicmass "57.93534" ; chebi:smiles "[Ni]" ; oboInOwl:hasAlternativeId "CHEBI:25515", "CHEBI:7552" ; oboInOwl:hasDbXref "CAS:7440-02-0", "Gmelin:16229", "KEGG:C00291", "PMID:12756270", "PMID:14634084", "PMID:14734778", "PMID:15165199", "PMID:19828094", "PMID:20477134", "PMID:22762130", "PMID:23142754", "PMID:23317102", "PMID:23692032", "PMID:23692035", "PMID:23723488", "PMID:23834453", "PMID:23857010", "PMID:23895079", "PMID:23909687", "PMID:9060994", "PMID:9886425", "Reaxys:4122946", "WebElements:Ni", "Wikipedia:Nickel" ; oboInOwl:hasExactSynonym "nickel" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "28Ni", "Ni", "Nickel", "Raney alloy", "niccolum", "nickel", "niquel" ; oboInOwl:id "CHEBI:28112" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nickel atom" ; rdfs:subClassOf obo:CHEBI_33362, obo:CHEBI_88184, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_53000 ] . obo:CHEBI_2814 obo:IAO_0000115 "A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine." ; chebi:charge "0" ; chebi:formula "C8H13NO2" ; chebi:inchi "InChI=1S/C8H13NO2/c1-9-5-3-4-7(6-9)8(10)11-2/h4H,3,5-6H2,1-2H3" ; chebi:inchikey "HJJPJSXJAXAIPN-UHFFFAOYSA-N" ; chebi:mass "155.19430" ; chebi:monoisotopicmass "155.09463" ; chebi:smiles "COC(=O)C1=CCCN(C)C1" ; oboInOwl:hasDbXref "CAS:63-75-2", "DrugBank:DB04365", "HMDB:HMDB0030353", "KEGG:C10129", "KNApSAcK:C00002020", "LINCS:LSM-15214", "PMID:21809341", "PMID:22493525", "PMID:23525646", "PMID:23895157", "Patent:CN101411705", "Patent:CN102464607", "Patent:US2506458", "Reaxys:123045", "Wikipedia:Arecoline" ; oboInOwl:hasExactSynonym "methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "arecaidine methyl ester", "arecaline", "arecholine", "arekolin", "methylarecaiden", "methylarecaidin" ; oboInOwl:id "CHEBI:2814" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "arecoline" ; rdfs:subClassOf obo:CHEBI_25248, obo:CHEBI_26416, obo:CHEBI_26921, obo:CHEBI_51702, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38325 ] . obo:CHEBI_28260 obo:IAO_0000115 "An aldohexose that is the C-4 epimer of glucose." ; chebi:charge "0" ; chebi:formula "C6H12O6" ; chebi:mass "180.156" ; chebi:monoisotopicmass "180.06339" ; oboInOwl:hasAlternativeId "CHEBI:24162", "CHEBI:33933", "CHEBI:5256" ; oboInOwl:hasDbXref "CAS:26566-61-0", "KEGG:C01582", "Wikipedia:Galactose" ; oboInOwl:hasExactSynonym "Galactose", "galacto-hexose", "galactose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Gal", "Galaktose" ; oboInOwl:id "CHEBI:28260" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "galactose" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33917, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ] . obo:CHEBI_28616 obo:IAO_0000115 "A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised." ; chebi:charge "0" ; chebi:formula "CH3NO2" ; chebi:inchi "InChI=1S/CH3NO2/c2-1(3)4/h2H2,(H,3,4)" ; chebi:inchikey "KXDHJXZQYSOELW-UHFFFAOYSA-N" ; chebi:mass "61.04006" ; chebi:monoisotopicmass "61.01638" ; chebi:smiles "NC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:22504", "CHEBI:23002", "CHEBI:3386", "CHEBI:44573" ; oboInOwl:hasDbXref "Beilstein:1734754", "CAS:463-77-4", "DrugBank:DB04261", "Gmelin:130345", "KEGG:C01563", "PDBeChem:OUT", "Wikipedia:Carbamic_acid" ; oboInOwl:hasExactSynonym "CARBAMIC ACID", "Carbamic acid", "carbamic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aminoameisensaeure", "Aminoformic acid", "Carbamate", "Carbamidsaeure" ; oboInOwl:id "CHEBI:28616" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbamic acid" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_35605, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_13941 ] . obo:CHEBI_28659 chebi:charge "0" ; chebi:formula "P" ; chebi:inchi "InChI=1S/P" ; chebi:inchikey "OAICVXFJPJFONN-UHFFFAOYSA-N" ; chebi:mass "30.97376" ; chebi:monoisotopicmass "30.97376" ; chebi:smiles "[P]" ; oboInOwl:hasAlternativeId "CHEBI:26080", "CHEBI:8168" ; oboInOwl:hasDbXref "CAS:7723-14-0", "Gmelin:16235", "KEGG:C06262", "WebElements:P" ; oboInOwl:hasExactSynonym "phosphorus" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "15P", "P", "Phosphor", "Phosphorus", "fosforo", "phosphore", "phosphorus" ; oboInOwl:id "CHEBI:28659" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphorus atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25585, obo:CHEBI_33300, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_28694 chebi:charge "0" ; chebi:formula "Cu" ; chebi:inchi "InChI=1S/Cu" ; chebi:inchikey "RYGMFSIKBFXOCR-UHFFFAOYSA-N" ; chebi:mass "63.54600" ; chebi:monoisotopicmass "62.92960" ; chebi:smiles "[Cu]" ; oboInOwl:hasAlternativeId "CHEBI:23376", "CHEBI:3874" ; oboInOwl:hasDbXref "CAS:7440-50-8", "Gmelin:16269", "KEGG:C00070", "WebElements:Cu" ; oboInOwl:hasExactSynonym "copper" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "29Cu", "Copper", "Cu", "Kupfer", "cobre", "copper", "cuivre", "cuprum" ; oboInOwl:id "CHEBI:28694" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "copper atom" ; rdfs:subClassOf obo:CHEBI_33366, obo:CHEBI_88184, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_27027 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ] . obo:CHEBI_28765 obo:IAO_0000115 "Any member of the phosphoinositide family of compounds, of which seven occur naturally." ; oboInOwl:hasAlternativeId "CHEBI:26037", "CHEBI:26038", "CHEBI:8135" ; oboInOwl:hasDbXref "PMID:16441841", "PMID:2538726" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "phosphatidylinositol phosphates" ; oboInOwl:id "CHEBI:28765" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphatidylinositol phosphate" ; rdfs:subClassOf obo:CHEBI_18179 . obo:CHEBI_28790 obo:IAO_0000115 "A primary amino compound that is the 5-hydroxy derivative of tryptamine." ; chebi:charge "0" ; chebi:formula "C10H12N2O" ; chebi:inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2" ; chebi:inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-N" ; chebi:mass "176.215" ; chebi:monoisotopicmass "176.09496" ; chebi:smiles "C1=CC(=CC=2C(=CNC12)CCN)O" ; oboInOwl:hasAlternativeId "CHEBI:1420", "CHEBI:26652", "CHEBI:49894" ; oboInOwl:hasDbXref "Beilstein:143524", "CAS:50-67-9", "Gmelin:1861995", "HMDB:HMDB0000259", "KEGG:C00780", "KNApSAcK:C00001429", "LINCS:LSM-6589", "MetaCyc:SEROTONIN", "PDBeChem:SRO", "PMID:18593914", "PMID:22770225", "PMID:24136337", "Reaxys:143524", "Wikipedia:Serotonin" ; oboInOwl:hasExactSynonym "3-(2-aminoethyl)-1H-indol-5-ol", "SEROTONIN", "Serotonin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3-(2-Aminoethyl)-1H-indol-5-ol", "5-HT", "5-Hydroxytryptamine", "Enteramine", "serotonine", "thrombocytin", "thrombotonin" ; oboInOwl:id "CHEBI:28790" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "serotonin" ; rdfs:subClassOf obo:CHEBI_25375, obo:CHEBI_27162, obo:CHEBI_33853, obo:CHEBI_50994, obo:CHEBI_84729, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25512 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16765 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_350546 ] . obo:CHEBI_28868 obo:IAO_0000115 "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.00950" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13634", "CHEBI:24022", "CHEBI:4985" ; oboInOwl:hasDbXref "KEGG:C02403", "PMID:18628202" ; oboInOwl:hasExactSynonym "Fatty acid anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Alkanate", "Fettsaeureanion", "Fettsaeureanionen", "a fatty acid", "acido graso anionico", "acidos grasos anionicos", "anion de l'acide gras", "fatty acid anions" ; oboInOwl:id "CHEBI:28868" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fatty acid anion" ; rdfs:subClassOf obo:CHEBI_18059, obo:CHEBI_35757, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35366 ] . obo:CHEBI_28874 obo:IAO_0000115 "Any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol." ; oboInOwl:hasAlternativeId "CHEBI:18877", "CHEBI:494" ; oboInOwl:hasDbXref "DrugBank:DB02144", "PMID:15634688", "PMID:15967713", "PMID:17417879", "PMID:18189424", "PMID:19456874", "PMID:23015060", "PMID:23118092", "Wikipedia:Phosphatidylinositol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "PI", "PtdIns", "phosphatidylinositols" ; oboInOwl:id "CHEBI:28874" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphatidylinositol" ; rdfs:subClassOf obo:CHEBI_36315 . obo:CHEBI_28938 obo:IAO_0000115 "An onium cation obtained by protonation of ammonia." ; chebi:charge "+1" ; chebi:formula "H4N" ; chebi:inchi "InChI=1S/H3N/h1H3/p+1" ; chebi:inchikey "QGZKDVFQNNGYKY-UHFFFAOYSA-O" ; chebi:mass "18.03850" ; chebi:monoisotopicmass "18.03383" ; chebi:smiles "[H][N+]([H])([H])[H]" ; oboInOwl:hasAlternativeId "CHEBI:22534", "CHEBI:49783", "CHEBI:7435" ; oboInOwl:hasDbXref "CAS:14798-03-9", "Gmelin:84", "KEGG:C01342", "MetaCyc:AMMONIUM", "MolBase:929", "PDBeChem:NH4", "PMID:11319011", "PMID:11341317", "PMID:12096804", "PMID:14512268", "PMID:14879753", "PMID:16345391", "PMID:16903292", "PMID:17392693", "PMID:18515490", "PMID:19199063", "PMID:19596600", "PMID:19682559", "PMID:19716251", "PMID:21993530", "PMID:22265469", "PMID:22524020", "PMID:22562341", "PMID:22631217", "Reaxys:16093784", "Wikipedia:Ammonium" ; oboInOwl:hasExactSynonym "ammonium", "azanium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ammonium(1+)", "NH4(+)", "NH4+", "[NH4](+)", "ammonium cation", "ammonium ion" ; oboInOwl:id "CHEBI:28938" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ammonium" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35106, obo:CHEBI_50313, obo:CHEBI_60242, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76971 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16134 ] . obo:CHEBI_28976 chebi:charge "0" ; chebi:formula "CH2O3" ; chebi:inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)" ; chebi:inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-N" ; chebi:mass "62.02478" ; chebi:monoisotopicmass "62.00039" ; chebi:smiles "OC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:13351", "CHEBI:23017", "CHEBI:23744", "CHEBI:3401" ; oboInOwl:hasDbXref "CAS:463-79-6", "Gmelin:25554", "KEGG:C01353", "PDBeChem:CO3" ; oboInOwl:hasExactSynonym "Carbonic acid", "carbonic acid", "dihydroxidooxidocarbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Dihydrogen carbonate", "H2CO3", "Koehlensaeure", "[CO(OH)2]" ; oboInOwl:id "CHEBI:28976" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbonic acid" ; rdfs:subClassOf obo:CHEBI_35605, obo:CHEBI_36961, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17544 ] . obo:CHEBI_29067 obo:IAO_0000115 "The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.00950" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13626", "CHEBI:13945", "CHEBI:23026", "CHEBI:58657" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a carboxylate", "carboxylic acid anions", "carboxylic anions" ; oboInOwl:id "CHEBI:29067" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carboxylic acid anion" ; rdfs:subClassOf obo:CHEBI_25696, obo:CHEBI_35406, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33575 ] . obo:CHEBI_29075 chebi:charge "0" ; chebi:formula "C5H10O7PR" ; chebi:mass "213.103" ; chebi:monoisotopicmass "213.01641" ; oboInOwl:hasAlternativeId "CHEBI:14616", "CHEBI:25404", "CHEBI:6983" ; oboInOwl:hasDbXref "KEGG:C02171" ; oboInOwl:hasExactSynonym "Mononucleotide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mononucleotides" ; oboInOwl:id "CHEBI:29075" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mononucleotide" ; rdfs:subClassOf obo:CHEBI_36976 . obo:CHEBI_29101 obo:IAO_0000115 "A monoatomic monocation obtained from sodium." ; chebi:charge "+1" ; chebi:formula "Na" ; chebi:inchi "InChI=1S/Na/q+1" ; chebi:inchikey "FKNQFGJONOIPTF-UHFFFAOYSA-N" ; chebi:mass "22.98977" ; chebi:monoisotopicmass "22.98922" ; chebi:smiles "[Na+]" ; oboInOwl:hasAlternativeId "CHEBI:26717", "CHEBI:49766", "CHEBI:9175" ; oboInOwl:hasDbXref "CAS:17341-25-2", "Gmelin:15196", "KEGG:C01330", "PDBeChem:NA" ; oboInOwl:hasExactSynonym "sodium cation", "sodium(1+)", "sodium(1+) ion", "sodium(I) cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Na(+)", "Na+", "SODIUM ION" ; oboInOwl:id "CHEBI:29101" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sodium(1+)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25414, obo:CHEBI_33504, obo:CHEBI_37246, obo:CHEBI_60242, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ] . obo:CHEBI_29108 chebi:charge "+2" ; chebi:formula "Ca" ; chebi:inchi "InChI=1S/Ca/q+2" ; chebi:inchikey "BHPQYMZQTOCNFJ-UHFFFAOYSA-N" ; chebi:mass "40.07800" ; chebi:monoisotopicmass "39.96149" ; chebi:smiles "[Ca++]" ; oboInOwl:hasAlternativeId "CHEBI:22988", "CHEBI:3308", "CHEBI:48760" ; oboInOwl:hasDbXref "CAS:14127-61-8", "Gmelin:6850", "KEGG:C00076", "PDBeChem:CA" ; oboInOwl:hasExactSynonym "calcium(2+)", "calcium(2+) ion", "calcium(II) cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CALCIUM ION", "Ca(2+)", "Ca2+", "calcium, doubly charged positive ion" ; oboInOwl:id "CHEBI:29108" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "calcium(2+)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_30412, obo:CHEBI_39123, obo:CHEBI_60240, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ] . obo:CHEBI_29192 chebi:charge "-1" ; chebi:formula "HO2" ; chebi:inchi "InChI=1S/H2O2/c1-2/h1-2H/p-1" ; chebi:inchikey "MHAJPDPJQMAIIY-UHFFFAOYSA-M" ; chebi:mass "33.00674" ; chebi:monoisotopicmass "32.99820" ; chebi:smiles "[H]O[O-]" ; oboInOwl:hasDbXref "CAS:14691-59-9", "Gmelin:507" ; oboInOwl:hasExactSynonym "dioxidanide", "hydrogen(peroxide)(1-)", "hydrogendioxide(1-)", "hydrogenperoxide(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HO2(-)", "HOO anion", "HOO(-)", "[HO2](-)" ; oboInOwl:id "CHEBI:29192" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogenperoxide(1-)" ; rdfs:subClassOf obo:CHEBI_33693, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16240 ] . obo:CHEBI_29195 chebi:charge "-1" ; chebi:formula "CNO" ; chebi:inchi "InChI=1S/CHNO/c2-1-3/h3H/p-1" ; chebi:inchikey "XLJMAIOERFSOGZ-UHFFFAOYSA-M" ; chebi:mass "42.01684" ; chebi:monoisotopicmass "41.99854" ; chebi:smiles "[O-]C#N" ; oboInOwl:hasAlternativeId "CHEBI:14037", "CHEBI:23419" ; oboInOwl:hasDbXref "CAS:661-20-1", "CAS:71000-82-3", "FooDB:FDB022835", "HMDB:HMDB0002078", "KEGG:C01417", "MetaCyc:CPD-69", "PMID:8323034", "UM-BBD_compID:c0568" ; oboInOwl:hasExactSynonym "cyanate", "nitridooxidocarbonate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cyanat", "OCN(-)", "Zyanat", "[C(N)O](-)", "cyanate ion" ; oboInOwl:id "CHEBI:29195" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyanate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35352, obo:CHEBI_36828, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_28024 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29202 ] . obo:CHEBI_29202 obo:IAO_0000115 "A colourless, volatile, poisonous inorganic compound with the formula HNCO; the simplest stable chemical compound that contains carbon, hydrogen, nitrogen, and oxygen, the four most commonly-found elements in organic chemistry and biology." ; chebi:charge "0" ; chebi:formula "CHNO" ; chebi:inchi "InChI=1S/CHNO/c2-1-3/h2H" ; chebi:inchikey "OWIKHYCFFJSOEH-UHFFFAOYSA-N" ; chebi:mass "43.02478" ; chebi:monoisotopicmass "43.00581" ; chebi:smiles "N=C=O" ; oboInOwl:hasDbXref "Beilstein:1616281", "CAS:75-13-8", "Gmelin:840", "PMID:19494520", "PMID:26124058", "PMID:26760716", "PMID:977566", "Reaxys:1616281" ; oboInOwl:hasExactSynonym "isocyanic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HN=C=O", "HNCO", "ICA", "[C(NH)O]", "carbimide", "hydrogen isocyanate", "isocyanate", "isocyansaeure", "isozyansaeure", "methenamide", "oxidoazanediidocarbon" ; oboInOwl:id "CHEBI:29202" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isocyanic acid" ; rdfs:subClassOf obo:CHEBI_33405, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29195 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_28024 ] . obo:CHEBI_29214 chebi:charge "0" ; chebi:formula "H2O3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)" ; chebi:inchikey "BDHFUVZGWQCTTF-UHFFFAOYSA-N" ; chebi:mass "82.08008" ; chebi:monoisotopicmass "81.97247" ; chebi:smiles "[H]S(O)(=O)=O" ; oboInOwl:hasDbXref "Gmelin:1404640" ; oboInOwl:hasExactSynonym "hydridohydroxidodioxidosulfur", "sulfonic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HSHO3", "Sulfonsaeure", "[SHO2(OH)]", "acide sulfonique", "sulphonic acid" ; oboInOwl:id "CHEBI:29214" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfonic acid" ; rdfs:subClassOf obo:CHEBI_33402, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33543 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_48854 ] . obo:CHEBI_29222 chebi:charge "-1" ; chebi:formula "ClO" ; chebi:inchi "InChI=1S/ClO/c1-2/q-1" ; chebi:inchikey "WQYVRQLZKVEZGA-UHFFFAOYSA-N" ; chebi:mass "51.45210" ; chebi:monoisotopicmass "50.96432" ; chebi:smiles "[O-]Cl" ; oboInOwl:hasDbXref "CAS:14380-61-1", "Gmelin:682", "Wikipedia:Hypochlorite" ; oboInOwl:hasExactSynonym "hypochlorite", "oxidochlorate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ClO(-)", "Hypochlorit", "[ClO](-)" ; oboInOwl:id "CHEBI:29222" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hypochlorite" ; rdfs:subClassOf obo:CHEBI_33437, obo:CHEBI_37750, obo:CHEBI_79389, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_24757 ] . obo:CHEBI_29228 obo:IAO_0000115 "A diatomic molecule containing covalently bonded hydrogen and fluorine atoms." ; chebi:charge "0" ; chebi:formula "FH" ; chebi:inchi "InChI=1S/FH/h1H" ; chebi:inchikey "KRHYYFGTRYWZRS-UHFFFAOYSA-N" ; chebi:mass "20.00634" ; chebi:monoisotopicmass "20.00623" ; chebi:smiles "F[H]" ; oboInOwl:hasDbXref "CAS:7664-39-3", "Drug_Central:4499", "Gmelin:166", "KEGG:C16487" ; oboInOwl:hasExactSynonym "Hydrogen fluoride", "fluorane", "fluoridohydrogen", "hydrogen fluoride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Fluoride", "Fluorwasserstoff", "HF", "Hydrogenfluorid", "[HF]", "fluorure d'hydrogene", "hydrofluoric acid" ; oboInOwl:id "CHEBI:29228" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogen fluoride" ; rdfs:subClassOf obo:CHEBI_18140, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17051 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_50314 ] . obo:CHEBI_29256 obo:IAO_0000115 "An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety." ; chebi:charge "0" ; chebi:formula "HSR" ; chebi:mass "33.07300" ; chebi:monoisotopicmass "32.97990" ; chebi:smiles "S[*]" ; oboInOwl:hasAlternativeId "CHEBI:13443", "CHEBI:13696", "CHEBI:17366", "CHEBI:26969", "CHEBI:8766", "CHEBI:9556" ; oboInOwl:hasDbXref "KEGG:C00145", "Wikipedia:Thiol" ; oboInOwl:hasExactSynonym "Thiol", "thiols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Mercaptan", "Merkaptan", "RSH", "a thiol", "mercaptans", "thiols" ; oboInOwl:id "CHEBI:29256" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "thiol" ; rdfs:subClassOf obo:CHEBI_33261, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29917 ] . obo:CHEBI_29337 chebi:charge "-1" ; chebi:formula "H2N" ; chebi:inchi "InChI=1S/H2N/h1H2/q-1" ; chebi:inchikey "HYGWNUKOUCZBND-UHFFFAOYSA-N" ; chebi:mass "16.02262" ; chebi:monoisotopicmass "16.01927" ; chebi:smiles "[H][N-][H]" ; oboInOwl:hasExactSynonym "amide", "azanide", "dihydridonitrate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NH2(-)" ; oboInOwl:id "CHEBI:29337" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "azanide" ; rdfs:subClassOf obo:CHEBI_35106, obo:CHEBI_79389, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29340 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16134 ] . obo:CHEBI_29340 obo:IAO_0000115 "A divalent inorganic anion resulting from the removal of two protons from ammonia." ; chebi:charge "-2" ; chebi:formula "HN" ; chebi:inchi "InChI=1S/HN/h1H/q-2" ; chebi:inchikey "DZQYTNGKSBCIOE-UHFFFAOYSA-N" ; chebi:mass "15.01468" ; chebi:monoisotopicmass "15.01200" ; chebi:smiles "[N--][H]" ; oboInOwl:hasExactSynonym "azanediide", "hydridonitrate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NH(2-)", "imide" ; oboInOwl:id "CHEBI:29340" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydridonitrate(2-)" ; rdfs:subClassOf obo:CHEBI_35106, obo:CHEBI_79388, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29337 ] . obo:CHEBI_29347 obo:IAO_0000115 "A carboxamide derived from a monocarboxylic acid." ; chebi:charge "0" ; chebi:formula "CNOR3" ; chebi:mass "42.01680" ; chebi:monoisotopicmass "41.99799" ; chebi:smiles "[*]N([*])C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13211", "CHEBI:22207", "CHEBI:25383", "CHEBI:6977" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monocarboxylic acid amides" ; oboInOwl:id "CHEBI:29347" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monocarboxylic acid amide" ; rdfs:subClassOf obo:CHEBI_37622 . obo:CHEBI_29360 chebi:charge "-2" ; chebi:formula "CH2" ; chebi:inchi "InChI=1S/CH2/h1H2/q-2" ; chebi:inchikey "PZPOWPOFQLSNJO-UHFFFAOYSA-N" ; chebi:mass "14.02658" ; chebi:monoisotopicmass "14.01675" ; chebi:smiles "[H][C--][H]" ; oboInOwl:hasDbXref "Beilstein:5915711", "Gmelin:322698" ; oboInOwl:hasExactSynonym "dihydridocarbonate(2-)", "methanediide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH2(2-)", "[CH2](2-)" ; oboInOwl:id "CHEBI:29360" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methanediide" ; rdfs:subClassOf obo:CHEBI_38222, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29438 ] . obo:CHEBI_29369 chebi:charge "0" ; chebi:formula "O2" ; chebi:mass "31.99880" ; chebi:monoisotopicmass "31.98983" ; chebi:smiles "O(O*)*" ; oboInOwl:hasExactSynonym "peroxy" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-OO-" ; oboInOwl:id "CHEBI:29369" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "peroxy group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:CHEBI_29438 chebi:charge "-1" ; chebi:formula "CH3" ; chebi:inchi "InChI=1S/CH3/h1H3/q-1" ; chebi:inchikey "LGRLWUINFJPLSH-UHFFFAOYSA-N" ; chebi:mass "15.03452" ; chebi:monoisotopicmass "15.02402" ; chebi:smiles "[H][C-]([H])[H]" ; oboInOwl:hasDbXref "Beilstein:1813938", "CAS:15194-58-8", "Gmelin:259263" ; oboInOwl:hasExactSynonym "methanide", "trihydridocarbonate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3(-)", "[CH3](-)", "lambda(2)-methanuide", "methyl anion" ; oboInOwl:id "CHEBI:29438" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methanide" ; rdfs:subClassOf obo:CHEBI_38222, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29360 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16183 ] . obo:CHEBI_29534 chebi:charge "0" ; chebi:formula "C48H72O14" ; chebi:inchi "InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1" ; chebi:inchikey "RRZXIRBKKLTSOM-XPNPUAGNSA-N" ; chebi:mass "873.07690" ; chebi:monoisotopicmass "872.49221" ; chebi:smiles "CC[C@H](C)[C@H]1O[C@@]2(C[C@@H]3C[C@@H](C\\C=C(C)\\[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](O)[C@H](C)O5)[C@H](C)O4)[C@@H](C)\\C=C\\C=C4/CO[C@@H]5[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)C=C[C@@H]1C" ; oboInOwl:hasDbXref "BPDB:8", "Beilstein:3645625", "CAS:65195-55-3", "KEGG:C11983", "LIPID_MAPS_instance:LMPK04000024", "MetaCyc:CPD-12963", "VSDB:8" ; oboInOwl:hasExactSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside", "Avermectin B1a" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "abamectin component B1a" ; oboInOwl:id "CHEBI:29534" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "avermectin B1a" ; rdfs:subClassOf obo:CHEBI_50344 . obo:CHEBI_29537 chebi:charge "0" ; chebi:formula "C47H70O14" ; chebi:inchi "InChI=1S/C47H70O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,16-18,24-25,27,29-30,32-44,48-49,51H,15,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m0/s1" ; chebi:inchikey "ZFUKERYTFURFGA-PVVXTEPVSA-N" ; chebi:mass "859.05030" ; chebi:monoisotopicmass "858.47656" ; chebi:smiles "[H][C@@]12C\\C=C(C)\\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\\C=C\\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(O2)O[C@]([H])(C(C)C)[C@@H](C)C=C1)[C@]34O" ; oboInOwl:hasDbXref "Beilstein:8399072", "CAS:65195-56-4", "KEGG:C11967", "LIPID_MAPS_instance:LMPK04000020", "MetaCyc:CPD-12964" ; oboInOwl:hasExactSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-6'-(propan-2-yl)-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside", "Avermectin B1b" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13S,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-6'-isopropyl-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside", "abamectin component B1b" ; oboInOwl:id "CHEBI:29537" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "avermectin B1b" ; rdfs:subClassOf obo:CHEBI_50344 . obo:CHEBI_29699 obo:IAO_0000115 "A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety." ; chebi:charge "0" ; chebi:formula "C25H38N4O16" ; chebi:mass "650.587" ; chebi:monoisotopicmass "650.22828" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](OC2O[C@H]([*]O)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC([*])=O)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "CAS:11089-65-9", "KEGG:C12063", "PMID:11478581", "PMID:11514096", "PMID:11732194", "PMID:11798249", "PMID:12093793", "PMID:12106388", "PMID:12136966", "PMID:12232600", "PMID:12232799", "PMID:12515321", "PMID:160437", "PMID:1624425", "PMID:3018444", "PMID:315774", "PMID:34700340", "PMID:34979291", "PMID:35233582", "PMID:35370192", "PMID:4624615", "PMID:4630978", "PMID:5103138", "PMID:5103535", "PMID:5168706", "PMID:6153524", "PMID:6813319", "PMID:6975776", "PMID:6992777", "PMID:701277", "PMID:7142115", "PMID:7144800", "PMID:7766032", "Wikipedia:Tunicamycin" ; oboInOwl:hasExactSynonym "Tunicamycin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:29699" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_60004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64228 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64245 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64246 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64248 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64250 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64255 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64256 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64257 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64271 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_64272 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64237 ] . obo:CHEBI_29917 chebi:charge "0" ; chebi:formula "HS" ; chebi:mass "33.074" ; chebi:monoisotopicmass "32.97990" ; chebi:smiles "*S[H]" ; oboInOwl:hasAlternativeId "CHEBI:26821", "CHEBI:29916" ; oboInOwl:hasExactSynonym "sulfanyl", "thiol", "thiol group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-SH", "HS-", "Mercaptogruppe", "Merkaptogruppe", "Sulfhydrylgruppe", "Thiolgruppe", "mercapto group", "sulfhydryl group", "sulphydryl group" ; oboInOwl:id "CHEBI:29917" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "thiol group" ; rdfs:subClassOf obo:CHEBI_33246, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_16136 ] . obo:CHEBI_29919 chebi:charge "-1" ; chebi:formula "HS" ; chebi:inchi "InChI=1S/H2S/h1H2/p-1" ; chebi:inchikey "RWSOTUBLDIXVET-UHFFFAOYSA-M" ; chebi:mass "33.07394" ; chebi:monoisotopicmass "32.98044" ; chebi:smiles "[S-][H]" ; oboInOwl:hasDbXref "CAS:15035-72-0", "Gmelin:24766" ; oboInOwl:hasExactSynonym "hydrogen(sulfide)(1-)", "hydrosulfide", "sulfanide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HS anion", "HS(-)", "hydrogen sulfide" ; oboInOwl:id "CHEBI:29919" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrosulfide" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33535, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15138 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16136 ] . obo:CHEBI_29922 chebi:charge "0" ; chebi:formula "HO3S" ; chebi:mass "81.07214" ; chebi:monoisotopicmass "80.96464" ; chebi:smiles "S(=O)(O)(*)=O" ; oboInOwl:hasDbXref "PDBeChem:SFO" ; oboInOwl:hasExactSynonym "SULFO GROUP", "hydroxydioxo-lambda(6)-sulfanyl", "hydroxysulfonyl", "sulfo" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-S(O)2(OH)" ; oboInOwl:id "CHEBI:29922" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfo group" ; rdfs:subClassOf obo:CHEBI_33246, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_29214 ] . obo:CHEBI_30052 chebi:charge "0" ; chebi:formula "Cu" ; chebi:inchi "InChI=1S/Cu" ; chebi:inchikey "RYGMFSIKBFXOCR-UHFFFAOYSA-N" ; chebi:mass "63.54600" ; chebi:monoisotopicmass "62.92960" ; chebi:smiles "[Cu]" ; oboInOwl:hasDbXref "CAS:7440-50-8" ; oboInOwl:hasExactSynonym "copper", "copper(0)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cu(0)", "Cun" ; oboInOwl:id "CHEBI:30052" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "copper(0)" ; rdfs:subClassOf obo:CHEBI_37404 . obo:CHEBI_30089 obo:IAO_0000115 "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid." ; chebi:charge "-1" ; chebi:formula "C2H3O2" ; chebi:inchi "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1" ; chebi:inchikey "QTBSBXVTEAMEQO-UHFFFAOYSA-M" ; chebi:mass "59.04402" ; chebi:monoisotopicmass "59.01385" ; chebi:smiles "CC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:13704", "CHEBI:22165", "CHEBI:40480" ; oboInOwl:hasDbXref "Beilstein:1901470", "CAS:71-50-1", "DrugBank:DB03166", "Gmelin:1379", "KEGG:C00033", "MetaCyc:ACET", "PDBeChem:ACT", "PMID:17190852", "PMID:22211106", "PMID:22371380", "Reaxys:1901470", "UM-BBD_compID:c0050", "Wikipedia:Acetate" ; oboInOwl:hasExactSynonym "acetate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ACETATE ION", "Azetat", "CH3-COO(-)", "Ethanoat", "MeCO2 anion", "acetic acid, ion(1-)", "ethanoate" ; oboInOwl:id "CHEBI:30089" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acetate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35757, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_15366 ] . obo:CHEBI_30145 chebi:charge "0" ; chebi:formula "Li" ; chebi:inchi "InChI=1S/Li" ; chebi:inchikey "WHXSMMKQMYFTQS-UHFFFAOYSA-N" ; chebi:mass "6.94100" ; chebi:monoisotopicmass "7.01600" ; chebi:smiles "[Li]" ; oboInOwl:hasDbXref "CAS:7439-93-2", "WebElements:Li" ; oboInOwl:hasExactSynonym "lithium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3Li", "Li", "Lithium", "lithium", "litio" ; oboInOwl:id "CHEBI:30145" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "lithium atom" ; rdfs:subClassOf obo:CHEBI_22314 . obo:CHEBI_30185 chebi:charge "0" ; chebi:formula "Zn" ; chebi:inchi "InChI=1S/Zn" ; chebi:inchikey "HCHKCACWOHOZIP-UHFFFAOYSA-N" ; chebi:mass "65.39000" ; chebi:monoisotopicmass "63.92914" ; chebi:smiles "[Zn]" ; oboInOwl:hasDbXref "CAS:7440-66-6", "DrugBank:DB01593" ; oboInOwl:hasExactSynonym "zinc(0)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Zn(0)", "Znn", "zinc" ; oboInOwl:id "CHEBI:30185" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "zinc(0)" ; rdfs:subClassOf obo:CHEBI_37253 . obo:CHEBI_30297 obo:IAO_0000115 "A trivalent inorganic anion obtained by removal of all three protons from antimonous acid." ; chebi:charge "-3" ; chebi:formula "O3Sb" ; chebi:inchi "InChI=1S/3O.Sb/q3*-1;" ; chebi:inchikey "JXYAODGLKNBUTA-UHFFFAOYSA-N" ; chebi:mass "169.75820" ; chebi:monoisotopicmass "168.89020" ; chebi:smiles "[O-][Sb]([O-])[O-]" ; oboInOwl:hasDbXref "PMID:17419726" ; oboInOwl:hasExactSynonym "antimonite", "trioxidoantimonate(3-)", "trioxoantimonate(3-)", "trioxoantimonate(III)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SbO3(3-)", "[SbO3](3-)" ; oboInOwl:id "CHEBI:30297" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimonite" ; rdfs:subClassOf obo:CHEBI_36921, obo:CHEBI_79387, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_49870 ] . obo:CHEBI_30320 chebi:charge "-1" ; chebi:formula "C2H3OS" ; chebi:inchi "InChI=1S/C2H4OS/c1-2(3)4/h1H3,(H,3,4)/p-1" ; chebi:inchikey "DUYAAUVXQSMXQP-UHFFFAOYSA-M" ; chebi:mass "75.11062" ; chebi:monoisotopicmass "74.99101" ; chebi:smiles "CC([S-])=O" ; oboInOwl:hasAlternativeId "CHEBI:15233", "CHEBI:26951" ; oboInOwl:hasDbXref "Beilstein:1848542", "Beilstein:3903387", "CAS:29632-72-2", "Gmelin:323277" ; oboInOwl:hasExactSynonym "ethanethioate", "thioacetate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Thioacetat" ; oboInOwl:id "CHEBI:30320" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "thioacetate" ; rdfs:subClassOf obo:CHEBI_35367, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_26952 ] . obo:CHEBI_30362 obo:IAO_0000115 "An alkane that is butane substituted by a methyl group at position 2." ; chebi:charge "0" ; chebi:formula "C5H12" ; chebi:inchi "InChI=1S/C5H12/c1-4-5(2)3/h5H,4H2,1-3H3" ; chebi:inchikey "QWTDNUCVQCZILF-UHFFFAOYSA-N" ; chebi:mass "72.14878" ; chebi:monoisotopicmass "72.09390" ; chebi:smiles "CCC(C)C" ; oboInOwl:hasDbXref "Beilstein:1730723", "CAS:78-78-4", "Gmelin:49318", "PMID:21481069", "PMID:23904008", "PMID:24833189", "PMID:24932627", "Reaxys:1730723", "Wikipedia:Isopentane" ; oboInOwl:hasExactSynonym "2-methylbutane", "isopentane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(CH3)2CH-CH2-CH3", "1,1,2-trimethylethane", "1,1-dimethylpropane", "R-601a", "dimethylethylmethane", "iso-C5H12", "iso-pentane", "isoamylhydride" ; oboInOwl:id "CHEBI:30362" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isopentane" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_18310, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_30412 chebi:charge "+2" ; chebi:mass "0.00000" ; chebi:smiles "[*++]" ; oboInOwl:hasAlternativeId "CHEBI:23856", "CHEBI:4665" ; oboInOwl:hasDbXref "KEGG:C00572" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Divalent cation", "divalent inorganic cations", "monoatomic dications" ; oboInOwl:id "CHEBI:30412" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic dication" ; rdfs:subClassOf obo:CHEBI_23906 . obo:CHEBI_30413 obo:IAO_0000115 "A heme is any tetrapyrrolic chelate of iron." ; oboInOwl:hasAlternativeId "CHEBI:14386", "CHEBI:24491" ; oboInOwl:hasDbXref "COMe:MOL000025", "DrugBank:DB03014", "KEGG:C00032" ; oboInOwl:hasExactSynonym "heme", "hemes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Haem", "haem", "haeme", "hem", "hemos" ; oboInOwl:id "CHEBI:30413" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heme" ; rdfs:subClassOf obo:CHEBI_25216, obo:CHEBI_33892, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25212 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_26348 ] . obo:CHEBI_30488 chebi:charge "+1" ; chebi:formula "H3S" ; chebi:inchi "InChI=1S/H2S/h1H2/p+1" ; chebi:inchikey "RWSOTUBLDIXVET-UHFFFAOYSA-O" ; chebi:mass "35.08982" ; chebi:monoisotopicmass "34.99500" ; chebi:smiles "[H][S+]([H])[H]" ; oboInOwl:hasDbXref "CAS:18155-21-0", "Gmelin:307" ; oboInOwl:hasExactSynonym "sulfanium", "sulfonium", "trihydridosulfur(1+)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H3S(+)", "H3S+", "[SH3](+)", "sulphonium" ; oboInOwl:id "CHEBI:30488" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfonium" ; rdfs:subClassOf obo:CHEBI_26830, obo:CHEBI_33535, obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16136 ] . obo:CHEBI_30512 chebi:charge "0" ; chebi:formula "Ag" ; chebi:inchi "InChI=1S/Ag" ; chebi:inchikey "BQCADISMDOOEFD-UHFFFAOYSA-N" ; chebi:mass "107.86820" ; chebi:monoisotopicmass "106.90509" ; chebi:smiles "[Ag]" ; oboInOwl:hasDbXref "CAS:7440-22-4", "WebElements:Ag" ; oboInOwl:hasExactSynonym "silver" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "47Ag", "Ag", "Silber", "argent", "argentum", "plata", "silver" ; oboInOwl:id "CHEBI:30512" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "silver atom" ; rdfs:subClassOf obo:CHEBI_33366 . obo:CHEBI_30513 chebi:charge "0" ; chebi:formula "Sb" ; chebi:inchi "InChI=1S/Sb" ; chebi:inchikey "WATWJIUSRGPENY-UHFFFAOYSA-N" ; chebi:mass "121.76000" ; chebi:monoisotopicmass "120.90381" ; chebi:smiles "[Sb]" ; oboInOwl:hasDbXref "WebElements:Sb" ; oboInOwl:hasExactSynonym "antimony" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "51Sb", "Antimon", "Sb", "antimoine", "antimonio", "antimony", "stibium" ; oboInOwl:id "CHEBI:30513" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimony atom" ; rdfs:subClassOf obo:CHEBI_137980, obo:CHEBI_33300 . obo:CHEBI_30566 obo:IAO_0000115 "An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid." ; chebi:charge "-1" ; chebi:formula "C4H8NO2" ; chebi:inchi "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)/p-1" ; chebi:inchikey "BTCSSZJGUNDROE-UHFFFAOYSA-M" ; chebi:mass "102.11186" ; chebi:monoisotopicmass "102.05605" ; chebi:smiles "NCCCC([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:11961", "CHEBI:20317" ; oboInOwl:hasDbXref "Beilstein:3536873", "Gmelin:559138", "KEGG:C00334", "PMID:12509893", "Reaxys:3536873" ; oboInOwl:hasExactSynonym "4-aminobutanoate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-Amino-butyrat", "4-Aminobutylate", "4-aminobutanoic acid ion (1-)", "4-aminobutyrate", "gamma-aminobutanoate", "gamma-aminobutyrate anion" ; oboInOwl:id "CHEBI:30566" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "gamma-aminobutyrate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_71666, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17968 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16865 ] . obo:CHEBI_30616 obo:IAO_0000115 "A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of ATP; major species present at pH 7.3." ; chebi:charge "-4" ; chebi:formula "C10H12N5O13P3" ; chebi:inchi "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/p-4/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "ZKHQWZAMYRWXGA-KQYNXXCUSA-J" ; chebi:mass "503.14946" ; chebi:monoisotopicmass "502.96664" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O" ; oboInOwl:hasDbXref "Beilstein:3581767", "Gmelin:342798" ; oboInOwl:hasExactSynonym "adenosine 5'-triphosphate(4-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ATP", "atp" ; oboInOwl:id "CHEBI:30616" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ATP(4-)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_61557, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_57299 ] . obo:CHEBI_30751 obo:IAO_0000115 "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects." ; chebi:charge "0" ; chebi:formula "CH2O2" ; chebi:inchi "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)" ; chebi:inchikey "BDAGIHXWWSANSR-UHFFFAOYSA-N" ; chebi:mass "46.02538" ; chebi:monoisotopicmass "46.00548" ; chebi:smiles "[H]C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:24082", "CHEBI:42460", "CHEBI:5145" ; oboInOwl:hasDbXref "BPDB:1749", "Beilstein:1209246", "CAS:64-18-6", "DrugBank:DB01942", "Gmelin:1008", "HMDB:HMDB0000142", "KEGG:C00058", "KNApSAcK:C00001182", "LIPID_MAPS_instance:LMFA01010040", "MetaCyc:FORMATE", "PDBeChem:FMT", "PMID:12591956", "PMID:14637377", "PMID:15811469", "PMID:16120414", "PMID:16185830", "PMID:16222862", "PMID:16230297", "PMID:16445901", "PMID:16465784", "PMID:18034701", "PMID:18397576", "PMID:22080171", "PMID:22280475", "PMID:22304812", "PMID:22385261", "PMID:22447125", "PMID:22483350", "PMID:22499553", "PMID:22540994", "PMID:22606986", "PMID:22622393", "PMID:3946945", "PMID:7361809", "Patent:CN101481304", "Reaxys:1209246", "Wikipedia:Formic_acid" ; oboInOwl:hasExactSynonym "FORMIC ACID", "Formic acid", "formic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Acide formique", "Ameisensaeure", "H-COOH", "HCO2H", "HCOOH", "Methanoic acid", "aminic acid", "bilorin", "formylic acid", "hydrogen carboxylic acid", "methoic acid" ; oboInOwl:id "CHEBI:30751" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "formic acid" ; rdfs:subClassOf obo:CHEBI_25384, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25212 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33282 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48356 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_74783 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15740 ] . obo:CHEBI_30772 obo:IAO_0000115 "A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group." ; chebi:charge "0" ; chebi:formula "C4H8O2" ; chebi:inchi "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)" ; chebi:inchikey "FERIUCNNQQJTOY-UHFFFAOYSA-N" ; chebi:mass "88.10510" ; chebi:monoisotopicmass "88.05243" ; chebi:smiles "CCCC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:113450", "CHEBI:22948", "CHEBI:3234", "CHEBI:41208" ; oboInOwl:hasDbXref "Beilstein:906770", "CAS:107-92-6", "DrugBank:DB03568", "Gmelin:26242", "HMDB:HMDB0000039", "KEGG:C00246", "KNApSAcK:C00001180", "LIPID_MAPS_instance:LMFA01010004", "MetaCyc:BUTYRIC_ACID", "PDBeChem:BUA", "PMID:10736622", "PMID:10956204", "PMID:11201044", "PMID:11208715", "PMID:11238216", "PMID:11305323", "PMID:12068484", "PMID:13678314", "PMID:14962641", "PMID:1542095", "PMID:15809727", "PMID:15810631", "PMID:15938880", "PMID:19318247", "PMID:19366864", "PMID:19703412", "PMID:21699495", "PMID:22038864", "PMID:22194341", "PMID:22322557", "PMID:22339023", "PMID:22466881", "Reaxys:906770", "Wikipedia:Butyric_acid" ; oboInOwl:hasExactSynonym "Butyric acid", "butanoic acid", "butyric acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-butanoic acid", "1-butyric acid", "1-propanecarboxylic acid", "4:0", "BUTANOIC ACID", "Butanoate", "Butanoic acid", "Buttersaeure", "C4:0", "CH3-[CH2]2-COOH", "acide butanoique", "acide butyrique", "butanic acid", "butoic acid", "ethylacetic acid", "n-butanoic acid", "n-butyric acid", "propanecarboxylic acid", "propylformic acid" ; oboInOwl:id "CHEBI:30772" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "butyric acid" ; rdfs:subClassOf obo:CHEBI_140601, obo:CHEBI_39418, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_131604 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84087 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17968 ] . obo:CHEBI_30776 obo:IAO_0000115 "A C6, straight-chain saturated fatty acid." ; chebi:charge "0" ; chebi:formula "C6H12O2" ; chebi:inchi "InChI=1S/C6H12O2/c1-2-3-4-5-6(7)8/h2-5H2,1H3,(H,7,8)" ; chebi:inchikey "FUZZWVXGSFPDMH-UHFFFAOYSA-N" ; chebi:mass "116.15830" ; chebi:monoisotopicmass "116.08373" ; chebi:smiles "CCCCCC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:24571", "CHEBI:40213", "CHEBI:5702" ; oboInOwl:hasDbXref "Beilstein:773837", "CAS:142-62-1", "ECMDB:ECMDB21229", "Gmelin:185066", "HMDB:HMDB0000535", "KEGG:C01585", "KNApSAcK:C00001218", "LIPID_MAPS_instance:LMFA01010006", "MetaCyc:HEXANOATE", "PDBeChem:6NA", "PMID:10685018", "PMID:1556177", "PMID:24357269", "PMID:24924750", "Reaxys:773837", "Wikipedia:Hexanoic_acid", "YMDB:YMDB01424" ; oboInOwl:hasExactSynonym "HEXANOIC ACID", "Hexanoic acid", "hexanoic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-hexanoic acid", "1-pentanecarboxylic acid", "6:0", "C6:0", "CH3-[CH2]4-COOH", "Hexanoate", "Hexylic acid", "Pentanecarboxylic acid", "butylacetic acid", "caproic acid", "capronic acid", "hexoic acid", "n-Caproic acid", "n-hexanoic acid", "n-hexoic acid", "n-hexylic acid", "pentiformic acid", "pentylformic acid" ; oboInOwl:id "CHEBI:30776" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hexanoic acid" ; rdfs:subClassOf obo:CHEBI_39418, obo:CHEBI_59554, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17120 ] . obo:CHEBI_30879 obo:IAO_0000115 "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom." ; chebi:charge "0" ; chebi:formula "HOR" ; chebi:mass "17.007" ; chebi:monoisotopicmass "17.00274" ; chebi:smiles "O[*]" ; oboInOwl:hasAlternativeId "CHEBI:13804", "CHEBI:22288", "CHEBI:2553" ; oboInOwl:hasDbXref "KEGG:C00069" ; oboInOwl:hasExactSynonym "Alcohol", "alcohols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an alcohol" ; oboInOwl:id "CHEBI:30879" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alcohol" ; rdfs:subClassOf obo:CHEBI_33822 . obo:CHEBI_30953 obo:IAO_0000115 "A diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms." ; chebi:charge "0" ; chebi:formula "C4H4N2" ; chebi:inchi "InChI=1S/C4H4N2/c1-2-6-4-3-5-1/h1-4H" ; chebi:inchikey "KYQCOXFCLRTKLS-UHFFFAOYSA-N" ; chebi:mass "80.08804" ; chebi:monoisotopicmass "80.03745" ; chebi:smiles "c1cnccn1" ; oboInOwl:hasDbXref "Beilstein:103905", "CAS:290-37-9", "Gmelin:1733", "HMDB:HMDB0034176", "PMID:24964033", "Reaxys:103905", "Wikipedia:Pyrazine" ; oboInOwl:hasExactSynonym "pyrazine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,4-Diazin", "1,4-diazine", "Pyrazin", "p-diazine", "paradiazine", "pyz" ; oboInOwl:id "CHEBI:30953" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyrazine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_38314, obo:CHEBI_38627, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83056 ] . obo:CHEBI_30985 obo:IAO_0000115 "A bipyridine in which the two pyridine moieties are linked by a bond between positions C-4 and C-4'." ; chebi:charge "0" ; chebi:formula "C10H8N2" ; chebi:inchi "InChI=1S/C10H8N2/c1-5-11-6-2-9(1)10-3-7-12-8-4-10/h1-8H" ; chebi:inchikey "MWVTWFVJZLCBMC-UHFFFAOYSA-N" ; chebi:mass "156.18400" ; chebi:monoisotopicmass "156.06875" ; chebi:smiles "c1cc(ccn1)-c1ccncc1" ; oboInOwl:hasDbXref "Beilstein:113176", "CAS:553-26-4", "Gmelin:3759", "PMID:24022647", "PMID:24358992", "PMID:24446585", "Reaxys:113176", "Wikipedia:4,4%27-Bipyridine" ; oboInOwl:hasExactSynonym "4,4'-bipyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4,4'-bipyridyl", "4,4'-bpy", "4,4'-dipyridine", "4,4'-dipyridyl", "4,4-Bipyridin", "4-(4-pyridyl)pyridine", "gamma,gamma'-bipyridyl", "gamma,gamma'-dipyridyl" ; oboInOwl:id "CHEBI:30985" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "4,4'-bipyridine" ; rdfs:subClassOf obo:CHEBI_35545 . obo:CHEBI_31206 obo:IAO_0000115 "An inorganic chloride having ammonium as the counterion." ; chebi:charge "0" ; chebi:formula "Cl.H4N", "ClH4N" ; chebi:inchi "InChI=1S/ClH.H3N/h1H;1H3" ; chebi:inchikey "NLXLAEXVIDQMFP-UHFFFAOYSA-N" ; chebi:mass "53.49120" ; chebi:monoisotopicmass "53.00323" ; chebi:smiles "[Cl-].[H][N+]([H])([H])[H]" ; oboInOwl:hasDbXref "CAS:12125-02-9", "Gmelin:10120", "KEGG:C12538", "KEGG:D01139", "Wikipedia:Ammonium_Chloride" ; oboInOwl:hasExactSynonym "Ammonium chloride", "ammonium chloride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ammoniumchlorid", "NH4Cl", "[NH4]Cl", "azanium chloride" ; oboInOwl:id "CHEBI:31206" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ammonium chloride" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_36093, obo:CHEBI_47704, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_173084 ] . obo:CHEBI_32442 obo:IAO_0000115 "The L-enantiomer of cysteinate(1-)." ; chebi:charge "-1" ; chebi:formula "C3H6NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-M" ; chebi:mass "120.15128" ; chebi:monoisotopicmass "120.01247" ; chebi:smiles "N[C@@H](CS)C([O-])=O" ; oboInOwl:hasDbXref "Beilstein:4128886", "Gmelin:325857", "Reaxys:4128886" ; oboInOwl:hasExactSynonym "L-cysteinate(1-)", "hydrogen L-cysteinate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R)-2-amino-3-mercaptopropanoate", "(2R)-2-amino-3-sulfanylpropanoate", "L-cysteine anion", "L-cysteine monoanion" ; oboInOwl:id "CHEBI:32442" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-cysteinate(1-)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_32456, obo:CHEBI_59814, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32443 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17561 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35235 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32449 ] . obo:CHEBI_32443 obo:IAO_0000115 "The L-enantiomer of cysteinate(2-)." ; chebi:charge "-2" ; chebi:formula "C3H5NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-L" ; chebi:mass "119.14334" ; chebi:monoisotopicmass "119.00520" ; chebi:smiles "N[C@@H](C[S-])C([O-])=O" ; oboInOwl:hasDbXref "Beilstein:5921923", "Gmelin:325856", "Reaxys:5921923" ; oboInOwl:hasExactSynonym "L-cysteinate", "L-cysteinate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R)-2-amino-3-sulfidopropanoate", "L-cysteine dianion" ; oboInOwl:id "CHEBI:32443" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-cysteinate(2-)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_32457, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32442 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32450 ] . obo:CHEBI_32445 obo:IAO_0000115 "The L-enantiomer of cysteinium." ; chebi:charge "+1" ; chebi:formula "C3H8NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-O" ; chebi:mass "122.16716" ; chebi:monoisotopicmass "122.02703" ; chebi:smiles "[NH3+][C@@H](CS)C(O)=O" ; oboInOwl:hasDbXref "Gmelin:325860" ; oboInOwl:hasExactSynonym "L-cysteinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(1R)-1-carboxy-2-mercaptoethanaminium", "(1R)-1-carboxy-2-sulfanylethanaminium", "L-cysteine cation", "L-cysteinium(1+)" ; oboInOwl:id "CHEBI:32445" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-cysteinium" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_32458, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17561 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_35235 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32451 ] . obo:CHEBI_32449 obo:IAO_0000115 "The D-enantiomer of cysteinate(1-)." ; chebi:charge "-1" ; chebi:formula "C3H6NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-M" ; chebi:mass "120.15128" ; chebi:monoisotopicmass "120.01247" ; chebi:smiles "N[C@H](CS)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:1006156" ; oboInOwl:hasExactSynonym "D-cysteinate(1-)", "hydrogen D-cysteinate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2S)-2-amino-3-mercaptopropanoate", "(2S)-2-amino-3-sulfanylpropanoate", "D-cysteine monoanion" ; oboInOwl:id "CHEBI:32449" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-cysteinate(1-)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_32456, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32450 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16375 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35236 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32442 ] . obo:CHEBI_32450 obo:IAO_0000115 "The D-enantiomer of cysteinate(2-)." ; chebi:charge "-2" ; chebi:formula "C3H5NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-L" ; chebi:mass "119.14334" ; chebi:monoisotopicmass "119.00520" ; chebi:smiles "N[C@H](C[S-])C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:1342792" ; oboInOwl:hasExactSynonym "D-cysteinate", "D-cysteinate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2S)-2-amino-3-sulfidopropanoate", "D-cysteine dianion" ; oboInOwl:id "CHEBI:32450" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-cysteinate(2-)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_32457, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32449 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32443 ] . obo:CHEBI_32451 obo:IAO_0000115 "The D-enantiomer of cysteinium." ; chebi:charge "+1" ; chebi:formula "C3H8NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-O" ; chebi:mass "122.16716" ; chebi:monoisotopicmass "122.02703" ; chebi:smiles "[NH3+][C@H](CS)C(O)=O" ; oboInOwl:hasDbXref "Gmelin:363237" ; oboInOwl:hasExactSynonym "D-cysteinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(1S)-1-carboxy-2-mercaptoethanaminium", "(1S)-1-carboxy-2-sulfanylethanaminium", "D-cysteine cation" ; oboInOwl:id "CHEBI:32451" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-cysteinium" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_32458, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16375 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_35236 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_32445 ] . obo:CHEBI_32456 obo:IAO_0000115 "A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group." ; chebi:charge "-1" ; chebi:formula "C3H6NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-1" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-M" ; chebi:mass "120.15128" ; chebi:monoisotopicmass "120.01247" ; chebi:smiles "NC(CS)C([O-])=O" ; oboInOwl:hasDbXref "Beilstein:4128885", "Gmelin:363235", "Reaxys:4128885" ; oboInOwl:hasExactSynonym "cysteinate(1-)", "hydrogen cysteinate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-amino-3-mercaptopropanoate", "2-amino-3-sulfanylpropanoate", "cys(-)", "cysteine monoanion" ; oboInOwl:id "CHEBI:32456" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cysteinate(1-)" ; rdfs:subClassOf obo:CHEBI_33558, obo:CHEBI_63470, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32457 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_15356 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35237 ] . obo:CHEBI_32457 chebi:charge "-2" ; chebi:formula "C3H5NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p-2" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-L" ; chebi:mass "119.14334" ; chebi:monoisotopicmass "119.00520" ; chebi:smiles "NC(C[S-])C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:49990" ; oboInOwl:hasExactSynonym "cysteinate", "cysteinate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-amino-3-sulfidopropanoate", "cysteine dianion" ; oboInOwl:id "CHEBI:32457" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cysteinate(2-)" ; rdfs:subClassOf obo:CHEBI_33558, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32456 ] . obo:CHEBI_32458 chebi:charge "+1" ; chebi:formula "C3H8NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/p+1" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-O" ; chebi:mass "122.16716" ; chebi:monoisotopicmass "122.02703" ; chebi:smiles "[NH3+]C(CS)C(O)=O" ; oboInOwl:hasDbXref "Gmelin:325859" ; oboInOwl:hasExactSynonym "1-carboxy-2-sulfanylethanaminium", "cysteinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-carboxy-2-mercaptoethanaminium", "H2cys(+)", "cysteine cation" ; oboInOwl:id "CHEBI:32458" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cysteinium" ; rdfs:subClassOf obo:CHEBI_33719, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15356 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_35237 ] . obo:CHEBI_32563 obo:IAO_0000115 "An alpha-amino-acid anion that is the conjugate base of lysine, arising from deprotonation of the carboxy group." ; chebi:charge "-1" ; chebi:formula "C6H13N2O2" ; chebi:inchi "InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p-1" ; chebi:inchikey "KDXKERNSBIXSRK-UHFFFAOYSA-M" ; chebi:mass "145.17970" ; chebi:monoisotopicmass "145.09825" ; chebi:smiles "NCCCCC(N)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:815095" ; oboInOwl:hasExactSynonym "lysinate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,6-diaminohexanoate", "lys(-)", "lysinate(1-)", "lysine anion" ; oboInOwl:id "CHEBI:32563" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "lysinate" ; rdfs:subClassOf obo:CHEBI_33558, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_25094 ] . obo:CHEBI_32564 obo:IAO_0000115 "An alpha-amino-acid cation that is the conjugate acid of lysine, having two cationic amino groups and an anionic carboxy group." ; chebi:charge "+1" ; chebi:formula "C6H15N2O2" ; chebi:inchi "InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+1" ; chebi:inchikey "KDXKERNSBIXSRK-UHFFFAOYSA-O" ; chebi:mass "147.19558" ; chebi:monoisotopicmass "147.11280" ; chebi:smiles "[NH3+]CCCCC([NH3+])C([O-])=O" ; oboInOwl:hasExactSynonym "lysinium", "lysinium(1+)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,6-diammoniohexanoate", "lysine monocation" ; oboInOwl:id "CHEBI:32564" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "lysinium(1+)" ; rdfs:subClassOf obo:CHEBI_33719, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_25094 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32565 ] . obo:CHEBI_32565 obo:IAO_0000115 "An alpha-amino-acid cation obtained by protonation of both amino groups of lysine." ; chebi:charge "+2" ; chebi:formula "C6H16N2O2" ; chebi:inchi "InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/p+2" ; chebi:inchikey "KDXKERNSBIXSRK-UHFFFAOYSA-P" ; chebi:mass "148.20352" ; chebi:monoisotopicmass "148.12008" ; chebi:smiles "[NH3+]CCCCC([NH3+])C(O)=O" ; oboInOwl:hasExactSynonym "lysinediium", "lysinium(2+)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-carboxypentane-1,5-diaminium", "lysine dication" ; oboInOwl:id "CHEBI:32565" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "lysinium(2+)" ; rdfs:subClassOf obo:CHEBI_33719, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32564 ] . obo:CHEBI_32876 obo:IAO_0000115 "A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups." ; chebi:charge "0" ; chebi:formula "NR3" ; chebi:mass "14.00670" ; chebi:monoisotopicmass "14.00307" ; chebi:smiles "[*]N([*])[*]" ; oboInOwl:hasAlternativeId "CHEBI:26879", "CHEBI:9458" ; oboInOwl:hasDbXref "KEGG:C02196" ; oboInOwl:hasExactSynonym "Tertiary amine", "tertiary amines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "R3N", "tertiaeres Amin" ; oboInOwl:id "CHEBI:32876" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tertiary amine" ; rdfs:subClassOf obo:CHEBI_32952, obo:CHEBI_50996 . obo:CHEBI_32877 obo:IAO_0000115 "A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group." ; chebi:charge "0" ; chebi:formula "H2NR" ; chebi:mass "16.02260" ; chebi:monoisotopicmass "16.01872" ; chebi:smiles "N[*]" ; oboInOwl:hasAlternativeId "CHEBI:26263", "CHEBI:26265", "CHEBI:8407", "CHEBI:8409" ; oboInOwl:hasDbXref "KEGG:C00375", "KEGG:C00893", "KEGG:C02580" ; oboInOwl:hasExactSynonym "Primary amine", "primary amines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Primary monoamine", "R-NH2", "RCH2NH2", "primaeres Amin" ; oboInOwl:id "CHEBI:32877" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "primary amine" ; rdfs:subClassOf obo:CHEBI_32952, obo:CHEBI_50994 . obo:CHEBI_32952 obo:IAO_0000115 "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups." ; oboInOwl:hasAlternativeId "CHEBI:13814", "CHEBI:22474", "CHEBI:2641" ; oboInOwl:hasDbXref "KEGG:C00706" ; oboInOwl:hasExactSynonym "Amine", "amines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Amin", "Substituted amine" ; oboInOwl:id "CHEBI:32952" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amine" ; rdfs:subClassOf obo:CHEBI_50047 . obo:CHEBI_32954 chebi:charge "0" ; chebi:formula "C2H3NaO2" ; chebi:inchi "InChI=1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1" ; chebi:inchikey "VMHLLURERBWHNL-UHFFFAOYSA-M" ; chebi:mass "82.03379" ; chebi:monoisotopicmass "82.00307" ; chebi:smiles "[Na+].CC([O-])=O" ; oboInOwl:hasDbXref "Beilstein:3595639", "CAS:127-09-3", "Gmelin:20502", "Wikipedia:Sodium_Acetate" ; oboInOwl:hasExactSynonym "sodium acetate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Natriumazetat", "acetic acid, sodium salt", "anhydrous sodium acetate", "sodium acetate anhydrous" ; oboInOwl:id "CHEBI:32954" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sodium acetate" ; rdfs:subClassOf obo:CHEBI_38700, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_30089 ] . obo:CHEBI_32988 obo:IAO_0000115 "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; oboInOwl:hasAlternativeId "CHEBI:22473", "CHEBI:2633" ; oboInOwl:hasDbXref "KEGG:C00241" ; oboInOwl:hasExactSynonym "Amide", "amides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:32988" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amide" ; rdfs:subClassOf obo:CHEBI_51143 . obo:CHEBI_33083 obo:IAO_0000115 "An ortho- and peri-fused polycyclic arene consisting of a naphthalene and benzene unit connected by a five-membered ring." ; chebi:charge "0" ; chebi:formula "C16H10" ; chebi:inchi "InChI=1S/C16H10/c1-2-8-13-12(7-1)14-9-3-5-11-6-4-10-15(13)16(11)14/h1-10H" ; chebi:inchikey "GVEPBJHOBDJJJI-UHFFFAOYSA-N" ; chebi:mass "202.25060" ; chebi:monoisotopicmass "202.07825" ; chebi:smiles "c1ccc-2c(c1)-c1cccc3cccc-2c13" ; oboInOwl:hasDbXref "Beilstein:1907918", "CAS:206-44-0", "Gmelin:262216", "KEGG:C19425", "MetaCyc:CPD-15564", "PMID:15278918", "PMID:17258277", "PMID:23943046", "PMID:24151025", "Reaxys:1907918", "Wikipedia:Fluoranthene" ; oboInOwl:hasExactSynonym "fluoranthene" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "benzo[jk]fluorene" ; oboInOwl:id "CHEBI:33083" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluoranthene" ; rdfs:subClassOf obo:CHEBI_35300 . obo:CHEBI_33216 obo:IAO_0000115 "A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups." ; chebi:charge "0" ; chebi:formula "C15H16O2" ; chebi:inchi "InChI=1S/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3" ; chebi:inchikey "IISBACLAFKSPIT-UHFFFAOYSA-N" ; chebi:mass "228.291" ; chebi:monoisotopicmass "228.11503" ; chebi:smiles "CC(C)(C1=CC=C(O)C=C1)C1=CC=C(O)C=C1" ; oboInOwl:hasAlternativeId "CHEBI:22900", "CHEBI:31295", "CHEBI:47094" ; oboInOwl:hasDbXref "CAS:80-05-7", "DrugBank:DB06973", "HMDB:HMDB0032133", "KEGG:C13624", "LINCS:LSM-37080", "PDBeChem:2OH", "PMID:10593191", "PMID:11361040", "PMID:12860292", "PMID:15936980", "PMID:16904728", "PMID:24471646", "PMID:25042713", "PMID:25148994", "PMID:25524584", "PMID:25569640", "PMID:25637671", "PMID:25663485", "Reaxys:1107700", "UM-BBD_compID:c0764", "Wikipedia:Bisphenol_A" ; oboInOwl:hasExactSynonym "4,4'-(propane-2,2-diyl)diphenol", "Bisphenol A", "bisphenol A" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2, 2-Bis(4-hydroxyphenyl)propane", "2,2-Bis(4'-hydroxyphenyl)propane", "2,2-Bis(4-Hydroxyphenyl)propane", "2,2-Bis(p-hydroxyphenyl)propane", "2,2-Di(4-hydroxyphenyl)propane", "2,2-Di(4-phenylol)propane", "4,4'-(1-Methylethane-1,1-diyl)diphenol", "4,4'-(1-Methylethylidene)bisphenol", "4,4'-(Propane-2,2-diyl)diphenol", "4,4'-Bisphenol A", "4,4'-Isopropylidenediphenol", "BPA", "Dianin's compound", "bisphenol-A" ; oboInOwl:id "CHEBI:33216" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bisphenol A" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_22901, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76988 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ] . obo:CHEBI_33232 obo:IAO_0000115 "Intended use of the molecular entity or part thereof by humans." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33232" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "application" ; rdfs:subClassOf obo:CHEBI_50906 . obo:CHEBI_33233 obo:IAO_0000115 "A particle not known to have substructure." ; oboInOwl:hasExactSynonym "elementary particle" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "elementary particles" ; oboInOwl:id "CHEBI:33233" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fundamental particle" ; rdfs:subClassOf obo:CHEBI_36342 . obo:CHEBI_33238 obo:IAO_0000115 "A monoatomic entity is a molecular entity consisting of a single atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic entity", "monoatomic entities" ; oboInOwl:id "CHEBI:33238" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic entity" ; rdfs:subClassOf obo:CHEBI_33259 . obo:CHEBI_33240 obo:IAO_0000115 "An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands)." ; oboInOwl:hasExactSynonym "coordination entities", "coordination entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "coordination compounds" ; oboInOwl:id "CHEBI:33240" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "coordination entity" ; rdfs:subClassOf obo:CHEBI_37577 . obo:CHEBI_33241 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoacid derivatives" ; oboInOwl:id "CHEBI:33241" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxoacid derivative" ; rdfs:subClassOf obo:CHEBI_37577, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_24833 ] . obo:CHEBI_33242 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic hydrides" ; oboInOwl:id "CHEBI:33242" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic hydride" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_33692 . obo:CHEBI_33245 obo:IAO_0000115 "An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic fundamental parents", "organic parent hydrides" ; oboInOwl:id "CHEBI:33245" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic fundamental parent" ; rdfs:subClassOf obo:CHEBI_37175, obo:CHEBI_50860 . obo:CHEBI_33246 obo:IAO_0000115 "Any substituent group which does not contain carbon." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic groups" ; oboInOwl:id "CHEBI:33246" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic group" ; rdfs:subClassOf obo:CHEBI_24433 . obo:CHEBI_33247 obo:IAO_0000115 "Any substituent group or skeleton containing carbon." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic groups" ; oboInOwl:id "CHEBI:33247" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic group" ; rdfs:subClassOf obo:CHEBI_24433, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_50860 ] . obo:CHEBI_33248 obo:IAO_0000115 "A univalent group formed by removing a hydrogen atom from a hydrocarbon." ; oboInOwl:hasExactSynonym "hydrocarbyl group", "hydrocarbyl groups" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "groupe hydrocarbyle", "grupo hidrocarbilo", "grupos hidrocarbilo" ; oboInOwl:id "CHEBI:33248" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrocarbyl group" ; rdfs:subClassOf obo:CHEBI_33249, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_24632 ] . obo:CHEBI_33249 obo:IAO_0000115 "Any organic substituent group, regardless of functional type, having one free valence at a carbon atom." ; oboInOwl:hasExactSynonym "organyl group", "organyl groups" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "groupe organyle", "grupo organilo", "grupos organilo" ; oboInOwl:id "CHEBI:33249" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organyl group" ; rdfs:subClassOf obo:CHEBI_51447 . obo:CHEBI_33250 obo:IAO_0000115 "A chemical entity constituting the smallest component of an element having the chemical properties of the element." ; oboInOwl:hasAlternativeId "CHEBI:22671", "CHEBI:23907" ; oboInOwl:hasExactSynonym "atom" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atome", "atomo", "atoms", "atomus", "element", "elements" ; oboInOwl:id "CHEBI:33250" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "atom" ; rdfs:subClassOf obo:CHEBI_24431, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_10545 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33252 ] . obo:CHEBI_33252 obo:IAO_0000115 "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons." ; oboInOwl:hasExactSynonym "nucleus" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Atomkern", "Kern", "noyau", "noyau atomique", "nuclei", "nucleo", "nucleo atomico", "nucleus atomi" ; oboInOwl:id "CHEBI:33252" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "atomic nucleus" ; rdfs:subClassOf obo:CHEBI_36347, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33253 ] . obo:CHEBI_33253 obo:IAO_0000115 "Heavy nuclear particle: proton or neutron." ; oboInOwl:hasExactSynonym "nucleon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Nukleon", "Nukleonen", "nucleons" ; oboInOwl:id "CHEBI:33253" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleon" ; rdfs:subClassOf obo:CHEBI_36339, obo:CHEBI_36347 . obo:CHEBI_33256 obo:IAO_0000115 "A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; oboInOwl:hasExactSynonym "primary amide", "primary amides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33256" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "primary amide" ; rdfs:subClassOf obo:CHEBI_32988 . obo:CHEBI_33257 obo:IAO_0000115 "A derivative of two oxoacids RkE(=O)l(OH)m (l =/= 0) in which two acyl groups are attached to the amino or substituted amino group." ; oboInOwl:hasExactSynonym "secondary amide", "secondary amides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33257" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "secondary amide" ; rdfs:subClassOf obo:CHEBI_32988 . obo:CHEBI_33259 obo:IAO_0000115 "A molecular entity all atoms of which have the same atomic number." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "homoatomic entity", "homoatomic molecular entities", "homoatomic molecular entity" ; oboInOwl:id "CHEBI:33259" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental molecular entity" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_33261 obo:IAO_0000115 "An organosulfur compound is a compound containing at least one carbon-sulfur bond." ; oboInOwl:hasAlternativeId "CHEBI:23010", "CHEBI:25714" ; oboInOwl:hasDbXref "Wikipedia:Organosulfur_compounds" ; oboInOwl:hasExactSynonym "organosulfur compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organosulfur compounds" ; oboInOwl:id "CHEBI:33261" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organosulfur compound" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_36962 . obo:CHEBI_33273 obo:IAO_0000115 "An anion consisting of more than one atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic anions" ; oboInOwl:id "CHEBI:33273" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polyatomic anion" ; rdfs:subClassOf obo:CHEBI_22563, obo:CHEBI_36358 . obo:CHEBI_33280 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chemical messenger" ; oboInOwl:id "CHEBI:33280" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "molecular messenger" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_33281 obo:IAO_0000115 "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans." ; oboInOwl:hasAlternativeId "CHEBI:22582" ; oboInOwl:hasDbXref "PMID:12964249", "PMID:22117953", "PMID:22439833", "PMID:22849268", "PMID:22849276", "PMID:22958833" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Antibiotika", "Antibiotikum", "antibiotic", "antibiotics", "antibiotique", "antimicrobial", "antimicrobial agents", "antimicrobials", "microbicide", "microbicides" ; oboInOwl:id "CHEBI:33281" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimicrobial agent" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_33282 obo:IAO_0000115 "A substance (or active part thereof) that kills or slows the growth of bacteria." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antibacterial agents", "antibacterials", "bactericide", "bactericides" ; oboInOwl:id "CHEBI:33282" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antibacterial agent" ; rdfs:subClassOf obo:CHEBI_33281 . obo:CHEBI_33284 obo:IAO_0000115 "A nutrient is a food component that an organism uses to survive and grow." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nutrients" ; oboInOwl:id "CHEBI:33284" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nutrient" ; rdfs:subClassOf obo:CHEBI_78295 . obo:CHEBI_33285 obo:IAO_0000115 "A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heteroorganic entities", "organoelement compounds" ; oboInOwl:id "CHEBI:33285" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heteroorganic entity" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_33286 obo:IAO_0000115 "An agrochemical is a substance that is used in agriculture or horticulture." ; oboInOwl:hasDbXref "Wikipedia:Agrochemical" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agrichemical", "agrichemicals", "agricultural chemicals", "agrochemicals" ; oboInOwl:id "CHEBI:33286" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "agrochemical" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_33287 obo:IAO_0000115 "A fertilizer is any substance that is added to soil or water to assist the growth of plants." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fertiliser", "fertilizers" ; oboInOwl:id "CHEBI:33287" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fertilizer" ; rdfs:subClassOf obo:CHEBI_33286 . obo:CHEBI_33290 obo:IAO_0000115 "A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food material", "food materials", "food role", "foods", "foodstuff", "foodstuffs" ; oboInOwl:id "CHEBI:33290" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "food" ; rdfs:subClassOf obo:CHEBI_52211, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_78295 ] . obo:CHEBI_33292 obo:IAO_0000115 "An energy-rich substance that can be transformed with release of usable energy." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33292" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fuel" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_33296 obo:IAO_0000115 "A molecular entity containing one or more atoms of an alkali metal." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkali metal molecular entities" ; oboInOwl:id "CHEBI:33296" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkali metal molecular entity" ; rdfs:subClassOf obo:CHEBI_33674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22314 ] . obo:CHEBI_33299 obo:IAO_0000115 "An alkaline earth molecular entity is a molecular entity containing one or more atoms of an alkaline earth metal." ; oboInOwl:hasExactSynonym "alkaline earth molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkaline earth compounds", "alkaline earth molecular entities", "alkaline-earth compounds" ; oboInOwl:id "CHEBI:33299" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkaline earth molecular entity" ; rdfs:subClassOf obo:CHEBI_33674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22313 ] . obo:CHEBI_33300 obo:IAO_0000115 "Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth." ; oboInOwl:hasExactSynonym "pnictogens" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "group 15 elements", "group V elements", "nitrogenoideos", "nitrogenoides", "pnictogene", "pnictogenes" ; oboInOwl:id "CHEBI:33300" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pnictogen" ; rdfs:subClassOf obo:CHEBI_33560 . obo:CHEBI_33302 obo:IAO_0000115 "A p-block molecular entity containing any pnictogen." ; oboInOwl:hasExactSynonym "pnictogen molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pnictogen molecular entities" ; oboInOwl:id "CHEBI:33302" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pnictogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33300 ] . obo:CHEBI_33303 obo:IAO_0000115 "Any p-block element belonging to the group 16 family of the periodic table." ; oboInOwl:hasDbXref "PMID:17084588" ; oboInOwl:hasExactSynonym "chalcogen", "chalcogens" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Chalkogen", "Chalkogene", "anfigeno", "anfigenos", "calcogeno", "calcogenos", "chalcogene", "chalcogenes", "group 16 elements", "group VI elements" ; oboInOwl:id "CHEBI:33303" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chalcogen" ; rdfs:subClassOf obo:CHEBI_33560 . obo:CHEBI_33304 obo:IAO_0000115 "Any p-block molecular entity containing a chalcogen." ; oboInOwl:hasExactSynonym "chalcogen molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcogen compounds", "chalcogen molecular entities" ; oboInOwl:id "CHEBI:33304" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chalcogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33303 ] . obo:CHEBI_33306 oboInOwl:hasExactSynonym "group 14 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon group element", "carbon group elements", "carbonoides", "cristallogene", "cristallogenes", "group IV elements" ; oboInOwl:id "CHEBI:33306" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbon group element atom" ; rdfs:subClassOf obo:CHEBI_33560 . obo:CHEBI_33307 obo:IAO_0000115 "An organic acid in which one or both oxygens of a carboxy group have been replaced by divalent sulfur." ; oboInOwl:hasExactSynonym "carbothioic acids", "thiocarboxylic acid", "thiocarboxylic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "thiocarboxylic acids" ; oboInOwl:id "CHEBI:33307" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "thiocarboxylic acid" ; rdfs:subClassOf obo:CHEBI_33261, obo:CHEBI_64709 . obo:CHEBI_33308 obo:IAO_0000115 "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl." ; chebi:charge "0" ; chebi:formula "CO2R2" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[*]C(=O)O[*]" ; oboInOwl:hasAlternativeId "CHEBI:13204", "CHEBI:23028", "CHEBI:3408" ; oboInOwl:hasDbXref "KEGG:C02391", "Wikipedia:Ester" ; oboInOwl:hasExactSynonym "Carboxylic ester", "carboxylic esters" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a carboxylic ester", "carboxylic acid esters" ; oboInOwl:id "CHEBI:33308" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carboxylic ester" ; rdfs:subClassOf obo:CHEBI_35701, obo:CHEBI_36586 . obo:CHEBI_33318 obo:IAO_0000115 "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table." ; oboInOwl:hasExactSynonym "main group elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Hauptgruppenelement", "Hauptgruppenelemente", "main group element" ; oboInOwl:id "CHEBI:33318" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "main group element atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_33340 oboInOwl:hasExactSynonym "group 12 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "zinc group element", "zinc group elements" ; oboInOwl:id "CHEBI:33340" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "zinc group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33352 oboInOwl:hasExactSynonym "group 7 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "manganese group element", "manganese group elements" ; oboInOwl:id "CHEBI:33352" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "manganese group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33356 oboInOwl:hasExactSynonym "group 8 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iron group element", "iron group elements" ; oboInOwl:id "CHEBI:33356" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iron group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33358 oboInOwl:hasExactSynonym "group 9 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cobalt group element", "cobalt group elements" ; oboInOwl:id "CHEBI:33358" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cobalt group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33362 oboInOwl:hasExactSynonym "group 10 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nickel group element", "nickel group elements" ; oboInOwl:id "CHEBI:33362" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nickel group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33366 oboInOwl:hasExactSynonym "group 11 elements" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "coinage metals", "copper group element", "copper group elements" ; oboInOwl:id "CHEBI:33366" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "copper group element atom" ; rdfs:subClassOf obo:CHEBI_33561 . obo:CHEBI_33402 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoacids of sulfur", "sulfur oxoacids" ; oboInOwl:id "CHEBI:33402" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur oxoacid" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_33484 . obo:CHEBI_33405 obo:IAO_0000115 "A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons)." ; oboInOwl:hasExactSynonym "hydracid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydracids" ; oboInOwl:id "CHEBI:33405" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydracid" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33608, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39141 ] . obo:CHEBI_33408 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pnictogen oxoacids" ; oboInOwl:id "CHEBI:33408" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pnictogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24833, obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138103 ] . obo:CHEBI_33424 oboInOwl:hasExactSynonym "sulfur oxoacid derivative" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfur oxoacid derivatives" ; oboInOwl:id "CHEBI:33424" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur oxoacid derivative" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_33241 . obo:CHEBI_33425 oboInOwl:hasExactSynonym "halogen oxoacid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogen oxoacids" ; oboInOwl:id "CHEBI:33425" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24471, obo:CHEBI_24833, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138103 ] . obo:CHEBI_33426 oboInOwl:hasExactSynonym "chlorine oxoacid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chlorine oxoacids" ; oboInOwl:id "CHEBI:33426" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chlorine oxoacid" ; rdfs:subClassOf obo:CHEBI_23117, obo:CHEBI_33425, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33437 ] . obo:CHEBI_33429 chebi:charge "-1" ; chebi:mass "0.00000" ; chebi:smiles "[*-]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic monoanions" ; oboInOwl:id "CHEBI:33429" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic monoanion" ; rdfs:subClassOf obo:CHEBI_23905, obo:CHEBI_36830 . obo:CHEBI_33431 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33431" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental chlorine" ; rdfs:subClassOf obo:CHEBI_23117, obo:CHEBI_33434 . obo:CHEBI_33432 chebi:charge "0" ; chebi:formula "Cl" ; chebi:mass "35.453" ; chebi:monoisotopicmass "34.96885" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic chlorine" ; oboInOwl:id "CHEBI:33432" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic chlorine" ; rdfs:subClassOf obo:CHEBI_33431, obo:CHEBI_33433 . obo:CHEBI_33433 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoatomic halogens" ; oboInOwl:id "CHEBI:33433" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic halogen" ; rdfs:subClassOf obo:CHEBI_33238 . obo:CHEBI_33434 oboInOwl:hasExactSynonym "elemental halogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "elemental halogens" ; oboInOwl:id "CHEBI:33434" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental halogen" ; rdfs:subClassOf obo:CHEBI_33259 . obo:CHEBI_33437 oboInOwl:hasExactSynonym "chlorine oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chlorine oxoanions" ; oboInOwl:id "CHEBI:33437" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chlorine oxoanion" ; rdfs:subClassOf obo:CHEBI_23117, obo:CHEBI_33443, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33426 ] . obo:CHEBI_33443 oboInOwl:hasExactSynonym "halogen oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogen oxoanions" ; oboInOwl:id "CHEBI:33443" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halogen oxoanion" ; rdfs:subClassOf obo:CHEBI_24471, obo:CHEBI_24834, obo:CHEBI_35406 . obo:CHEBI_33447 obo:IAO_0000115 "Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid." ; oboInOwl:hasAlternativeId "CHEBI:15132", "CHEBI:25406", "CHEBI:26086", "CHEBI:9320" ; oboInOwl:hasDbXref "KEGG:C00934", "PMID:18186488" ; oboInOwl:hasExactSynonym "phospho sugar" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monosaccharide phosphates", "phospho sugars", "phosphorylated sugar", "phosphorylated sugars", "phosphosugar", "phosphosugars" ; oboInOwl:id "CHEBI:33447" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phospho sugar" ; rdfs:subClassOf obo:CHEBI_26816, obo:CHEBI_63367 . obo:CHEBI_33457 obo:IAO_0000115 "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons." ; oboInOwl:hasExactSynonym "phosphorus oxoacid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Oxosaeure des Phosphors", "oxoacids of phosphorus", "phosphorus oxoacids" ; oboInOwl:id "CHEBI:33457" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphorus oxoacid" ; rdfs:subClassOf obo:CHEBI_33408, obo:CHEBI_36360 . obo:CHEBI_33459 oboInOwl:hasExactSynonym "pnictogen oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pnictogen oxoanions" ; oboInOwl:id "CHEBI:33459" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pnictogen oxoanion" ; rdfs:subClassOf obo:CHEBI_33302, obo:CHEBI_35406 . obo:CHEBI_33461 oboInOwl:hasExactSynonym "phosphorus oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoanions of phosphorus", "phosphorus oxoanions" ; oboInOwl:id "CHEBI:33461" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphorus oxoanion" ; rdfs:subClassOf obo:CHEBI_24834, obo:CHEBI_26082, obo:CHEBI_33459 . obo:CHEBI_33482 oboInOwl:hasExactSynonym "sulfur oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoanions of sulfur", "sulfur oxoanions" ; oboInOwl:id "CHEBI:33482" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur oxoanion" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_33485 . obo:CHEBI_33484 oboInOwl:hasExactSynonym "chalcogen oxoacid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcogen oxoacids" ; oboInOwl:id "CHEBI:33484" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chalcogen oxoacid" ; rdfs:subClassOf obo:CHEBI_24833, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138103 ] . obo:CHEBI_33485 oboInOwl:hasExactSynonym "chalcogen oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcogen oxoanions" ; oboInOwl:id "CHEBI:33485" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chalcogen oxoanion" ; rdfs:subClassOf obo:CHEBI_35406 . obo:CHEBI_33497 obo:IAO_0000115 "A molecular entity containing one or more atoms of a transition element." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "transition element molecular entities", "transition metal molecular entity" ; oboInOwl:id "CHEBI:33497" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "transition element molecular entity" ; rdfs:subClassOf obo:CHEBI_23367, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_27081 ] . obo:CHEBI_33504 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkali metal cations" ; oboInOwl:id "CHEBI:33504" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkali metal cation" ; rdfs:subClassOf obo:CHEBI_25213 . obo:CHEBI_33513 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkaline earth cations", "alkaline earth metal cation", "alkaline-earth metal cations" ; oboInOwl:id "CHEBI:33513" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkaline earth cation" ; rdfs:subClassOf obo:CHEBI_25213, obo:CHEBI_33299 . obo:CHEBI_33521 obo:IAO_0000115 "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity." ; oboInOwl:hasAlternativeId "CHEBI:25217", "CHEBI:6788" ; oboInOwl:hasDbXref "KEGG:C00050", "PMID:21784043", "Wikipedia:Metal" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "elemental metal", "elemental metals", "metal element", "metal elements", "metals" ; oboInOwl:id "CHEBI:33521" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "metal atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_33535 oboInOwl:hasExactSynonym "sulfur hydride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydrides of sulfur", "sulfur hydrides", "sulphur hydrides" ; oboInOwl:id "CHEBI:33535" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur hydride" ; rdfs:subClassOf obo:CHEBI_26835, obo:CHEBI_36902 . obo:CHEBI_33543 obo:IAO_0000115 "The sulfur oxoanion formed by deprotonation of sulfonic acid." ; chebi:charge "-1" ; chebi:formula "HO3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h4H,(H,1,2,3)/p-1" ; chebi:inchikey "BDHFUVZGWQCTTF-UHFFFAOYSA-M" ; chebi:mass "81.07214" ; chebi:monoisotopicmass "80.96519" ; chebi:smiles "[H]S([O-])(=O)=O" ; oboInOwl:hasDbXref "Gmelin:971569" ; oboInOwl:hasExactSynonym "hydridotrioxidosulfate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SHO3(-)", "[SHO3](-)", "sulfonates" ; oboInOwl:id "CHEBI:33543" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfonate" ; rdfs:subClassOf obo:CHEBI_33482, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_29214 ] . obo:CHEBI_33551 obo:IAO_0000115 "An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon." ; chebi:charge "0" ; chebi:formula "HO3SR" ; chebi:mass "81.07100" ; chebi:monoisotopicmass "80.96464" ; chebi:smiles "OS([*])(=O)=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organosulfonic acids", "sulfonic acids" ; oboInOwl:id "CHEBI:33551" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organosulfonic acid" ; rdfs:subClassOf obo:CHEBI_33261, obo:CHEBI_33552, obo:CHEBI_64709, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29922 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33249 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33554 ] . obo:CHEBI_33552 oboInOwl:hasExactSynonym "sulfonic acid derivative" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "derivatives of sulfonic acid", "sulfonic acid derivatives" ; oboInOwl:id "CHEBI:33552" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfonic acid derivative" ; rdfs:subClassOf obo:CHEBI_33424, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_29214 ] . obo:CHEBI_33554 obo:IAO_0000115 "An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid." ; chebi:charge "-1" ; chebi:formula "O3SR" ; chebi:mass "80.064" ; chebi:monoisotopicmass "79.95681" ; chebi:smiles "*S([O-])(=O)=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organosulfonate", "organosulfonate oxoanions", "organosulfonates" ; oboInOwl:id "CHEBI:33554" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organosulfonate oxoanion" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33543 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33551 ] . obo:CHEBI_33558 obo:IAO_0000115 "An amino-acid anion obtained by deprotonation of any alpha-amino acid." ; oboInOwl:hasExactSynonym "alpha-amino-acid anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-amino acid anions", "alpha-amino-acid anions" ; oboInOwl:id "CHEBI:33558" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-amino-acid anion" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33704 ] . obo:CHEBI_33559 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "s-block element", "s-block elements" ; oboInOwl:id "CHEBI:33559" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "s-block element atom" ; rdfs:subClassOf obo:CHEBI_33250 . obo:CHEBI_33560 obo:IAO_0000115 "Any main group element atom belonging to the p-block of the periodic table." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "p-block element", "p-block elements" ; oboInOwl:id "CHEBI:33560" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "p-block element atom" ; rdfs:subClassOf obo:CHEBI_33318 . obo:CHEBI_33561 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "d-block element", "d-block elements" ; oboInOwl:id "CHEBI:33561" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "d-block element atom" ; rdfs:subClassOf obo:CHEBI_27081 . obo:CHEBI_33566 obo:IAO_0000115 "Any compound containing an o-diphenol component." ; chebi:charge "0" ; chebi:formula "C6H2O2R4" ; chebi:mass "106.079" ; chebi:monoisotopicmass "106.00548" ; chebi:smiles "OC1=C(O)C(*)=C(*)C(*)=C1*" ; oboInOwl:hasAlternativeId "CHEBI:134187", "CHEBI:13628", "CHEBI:18862" ; oboInOwl:hasDbXref "KEGG:C15571" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2-benzenediols", "a catechol", "benzene-1,2-diols" ; oboInOwl:id "CHEBI:33566" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "catechols" ; rdfs:subClassOf obo:CHEBI_33570 . obo:CHEBI_33567 obo:IAO_0000115 "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution." ; chebi:charge "0" ; chebi:formula "C8H9NO2R2" ; chebi:mass "151.163" ; chebi:monoisotopicmass "151.06333" ; oboInOwl:hasAlternativeId "CHEBI:23056", "CHEBI:3468" ; oboInOwl:hasDbXref "KEGG:C02012" ; oboInOwl:hasExactSynonym "Catecholamine", "catecholamines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "catecholamines" ; oboInOwl:id "CHEBI:33567" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "catecholamine" ; rdfs:subClassOf obo:CHEBI_25375, obo:CHEBI_33566 . obo:CHEBI_33570 oboInOwl:hasAlternativeId "CHEBI:22705", "CHEBI:22711" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33570" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "benzenediols" ; rdfs:subClassOf obo:CHEBI_33853 . obo:CHEBI_33575 obo:IAO_0000115 "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid." ; chebi:charge "0" ; chebi:formula "CHO2R" ; chebi:mass "45.01740" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "OC([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13428", "CHEBI:13627", "CHEBI:23027" ; oboInOwl:hasDbXref "PMID:17147560", "PMID:18433345", "Wikipedia:Carboxylic_acid" ; oboInOwl:hasExactSynonym "carboxylic acid", "carboxylic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Carbonsaeure", "Carbonsaeuren", "Karbonsaeure", "RC(=O)OH", "acide carboxylique", "acides carboxyliques", "acido carboxilico", "acidos carboxilicos" ; oboInOwl:id "CHEBI:33575" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carboxylic acid" ; rdfs:subClassOf obo:CHEBI_35605, obo:CHEBI_36586, obo:CHEBI_64709, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_46883 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29067 ] . obo:CHEBI_33576 obo:IAO_0000115 "Any carboxylic acid having a sulfur substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "S-containing carboxylic acid", "S-containing carboxylic acids", "sulfur-containing carboxylic acids" ; oboInOwl:id "CHEBI:33576" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur-containing carboxylic acid" ; rdfs:subClassOf obo:CHEBI_33261, obo:CHEBI_33575 . obo:CHEBI_33579 obo:IAO_0000115 "A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "main group compounds", "main group molecular entities" ; oboInOwl:id "CHEBI:33579" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "main group molecular entity" ; rdfs:subClassOf obo:CHEBI_23367, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33318 ] . obo:CHEBI_33582 oboInOwl:hasExactSynonym "carbon group molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon group molecular entities" ; oboInOwl:id "CHEBI:33582" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbon group molecular entity" ; rdfs:subClassOf obo:CHEBI_33675, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33306 ] . obo:CHEBI_33595 obo:IAO_0000115 "Any molecule that consists of a series of atoms joined together to form a ring." ; oboInOwl:hasDbXref "Wikipedia:Cyclic_compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic compounds" ; oboInOwl:id "CHEBI:33595" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic compound" ; rdfs:subClassOf obo:CHEBI_25367 . obo:CHEBI_33597 obo:IAO_0000115 "A cyclic compound having as ring members atoms of the same element only." ; oboInOwl:hasExactSynonym "homocyclic compound", "homocyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isocyclic compounds" ; oboInOwl:id "CHEBI:33597" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "homocyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33598 obo:IAO_0000115 "A homocyclic compound in which all of the ring members are carbon atoms." ; oboInOwl:hasExactSynonym "carbocyclic compound", "carbocyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbocycle" ; oboInOwl:id "CHEBI:33598" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbocyclic compound" ; rdfs:subClassOf obo:CHEBI_33597, obo:CHEBI_33832 . obo:CHEBI_33599 obo:IAO_0000115 "A compound having one atom as the only common member of two rings." ; oboInOwl:hasExactSynonym "spiro compound", "spiro compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "spiro-fused compounds", "spirocycle", "spirocycles", "spirocyclic compound", "spirocyclic compounds", "spirofused compounds" ; oboInOwl:id "CHEBI:33599" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "spiro compound" ; rdfs:subClassOf obo:CHEBI_33635 . obo:CHEBI_33608 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydrogen compounds", "hydrogen molecular entities" ; oboInOwl:id "CHEBI:33608" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_49637 ] . obo:CHEBI_33635 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polycyclic compounds" ; oboInOwl:id "CHEBI:33635" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polycyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33636 obo:IAO_0000115 "A molecule that features two fused rings." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bicyclic compounds" ; oboInOwl:id "CHEBI:33636" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bicyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33639 obo:IAO_0000115 "A polycyclic compound in which one ring contains two, and only two, atoms in common with each of two or more rings of a contiguous series of rings. Such compounds have n common faces and less than 2n common atoms." ; oboInOwl:hasExactSynonym "ortho- and peri-fused polycyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ortho- and peri-fused compounds" ; oboInOwl:id "CHEBI:33639" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ortho- and peri-fused compound" ; rdfs:subClassOf obo:CHEBI_35293 . obo:CHEBI_33653 obo:IAO_0000115 "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds." ; oboInOwl:hasExactSynonym "aliphatic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33653" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aliphatic compound" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_33655 obo:IAO_0000115 "A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character." ; oboInOwl:hasExactSynonym "aromatic compounds", "aromatic molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aromatics", "aromatische Verbindungen" ; oboInOwl:id "CHEBI:33655" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aromatic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33658 obo:IAO_0000115 "Any monocyclic or polycyclic aromatic hydrocarbon." ; oboInOwl:hasExactSynonym "arene", "arenes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aromatic hydrocarbons" ; oboInOwl:id "CHEBI:33658" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "arene" ; rdfs:subClassOf obo:CHEBI_33659, obo:CHEBI_33663 . obo:CHEBI_33659 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic aromatic compounds" ; oboInOwl:id "CHEBI:33659" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic aromatic compound" ; rdfs:subClassOf obo:CHEBI_33655, obo:CHEBI_33832 . obo:CHEBI_33661 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monocyclic compounds" ; oboInOwl:id "CHEBI:33661" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monocyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_33663 oboInOwl:hasExactSynonym "cyclic hydrocarbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic hydrocarbons" ; oboInOwl:id "CHEBI:33663" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic hydrocarbon" ; rdfs:subClassOf obo:CHEBI_24632, obo:CHEBI_33598 . obo:CHEBI_33666 oboInOwl:hasExactSynonym "polycyclic hydrocarbon", "polycyclic hydrocarbons" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33666" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polycyclic hydrocarbon" ; rdfs:subClassOf obo:CHEBI_33663, obo:CHEBI_35294 . obo:CHEBI_33670 oboInOwl:hasExactSynonym "heteromonocyclic compound", "heteromonocyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33670" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heteromonocyclic compound" ; rdfs:subClassOf obo:CHEBI_33661, obo:CHEBI_5686 . obo:CHEBI_33671 obo:IAO_0000115 "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom." ; oboInOwl:hasExactSynonym "heteropolycyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyheterocyclic compounds" ; oboInOwl:id "CHEBI:33671" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heteropolycyclic compound" ; rdfs:subClassOf obo:CHEBI_33635, obo:CHEBI_5686 . obo:CHEBI_33672 obo:IAO_0000115 "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom." ; oboInOwl:hasExactSynonym "heterobicyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33672" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heterobicyclic compound" ; rdfs:subClassOf obo:CHEBI_33636, obo:CHEBI_5686 . obo:CHEBI_33673 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "zinc group molecular entities" ; oboInOwl:id "CHEBI:33673" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "zinc group molecular entity" ; rdfs:subClassOf obo:CHEBI_33676, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33340 ] . obo:CHEBI_33674 obo:IAO_0000115 "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element." ; oboInOwl:hasExactSynonym "s-block molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "s-block compounds", "s-block molecular entities" ; oboInOwl:id "CHEBI:33674" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "s-block molecular entity" ; rdfs:subClassOf obo:CHEBI_33579, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33559 ] . obo:CHEBI_33675 obo:IAO_0000115 "A main group molecular entity that contains one or more atoms of a p-block element." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "p-block compounds", "p-block molecular entities", "p-block molecular entitiy" ; oboInOwl:id "CHEBI:33675" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "p-block molecular entity" ; rdfs:subClassOf obo:CHEBI_33579, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33560 ] . obo:CHEBI_33676 obo:IAO_0000115 "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element." ; oboInOwl:hasExactSynonym "d-block molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "d-block compounds", "d-block molecular entities" ; oboInOwl:id "CHEBI:33676" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "d-block molecular entity" ; rdfs:subClassOf obo:CHEBI_33497, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33561 ] . obo:CHEBI_33692 obo:IAO_0000115 "Hydrides are chemical compounds of hydrogen with other chemical elements." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33692" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrides" ; rdfs:subClassOf obo:CHEBI_33608, obo:CHEBI_37577 . obo:CHEBI_33693 oboInOwl:hasExactSynonym "oxygen hydride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hydrides of oxygen", "oxygen hydrides" ; oboInOwl:id "CHEBI:33693" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxygen hydride" ; rdfs:subClassOf obo:CHEBI_36902 . obo:CHEBI_33694 obo:IAO_0000115 "A macromolecule formed by a living organism." ; oboInOwl:hasExactSynonym "biopolymer" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Biopolymere", "biomacromolecules", "biopolymers" ; oboInOwl:id "CHEBI:33694" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "biomacromolecule" ; rdfs:subClassOf obo:CHEBI_33839, obo:CHEBI_50860 . obo:CHEBI_33695 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "genetically encoded biomacromolecules", "genetically encoded biopolymers", "information biomacromolecules", "information biopolymers", "information macromolecule", "information macromolecules" ; oboInOwl:id "CHEBI:33695" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "information biomacromolecule" ; rdfs:subClassOf obo:CHEBI_33694 . obo:CHEBI_33696 obo:IAO_0000115 "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid." ; oboInOwl:hasExactSynonym "nucleic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NA", "Nukleinsaeure", "Nukleinsaeuren", "acide nucleique", "acides nucleiques", "acido nucleico", "acidos nucleicos" ; oboInOwl:id "CHEBI:33696" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleic acid" ; rdfs:subClassOf obo:CHEBI_15986, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33791 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50297 ] . obo:CHEBI_33697 obo:IAO_0000115 "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins." ; oboInOwl:hasDbXref "CAS:63231-63-0" ; oboInOwl:hasExactSynonym "ribonucleic acid", "ribonucleic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RNA", "RNS", "Ribonukleinsaeure", "pentosenucleic acids", "ribonucleic acids", "ribose nucleic acid", "yeast nucleic acid" ; oboInOwl:id "CHEBI:33697" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribonucleic acid" ; rdfs:subClassOf obo:CHEBI_33696, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33792 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50299 ] . obo:CHEBI_33699 obo:IAO_0000115 "An RNA molecule that transfers the coding information for protein synthesis from the chromosomes to the ribosomes mRNA is formed from a DNA template by transcription. It may be a copy of a single gene or of several adjacent genes (polycistronic mRNA). On the ribosome, the sequence is converted into the programmed amino acid sequence through translation." ; oboInOwl:hasExactSynonym "messenger RNA" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mRNA", "template RNA" ; oboInOwl:id "CHEBI:33699" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "messenger RNA" ; rdfs:subClassOf obo:CHEBI_33697 . obo:CHEBI_33702 obo:IAO_0000115 "A cation consisting of more than one atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic cations" ; oboInOwl:id "CHEBI:33702" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polyatomic cation" ; rdfs:subClassOf obo:CHEBI_36358, obo:CHEBI_36916 . obo:CHEBI_33703 oboInOwl:hasExactSynonym "amino-acid cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino acid cation", "amino-acid cations" ; oboInOwl:id "CHEBI:33703" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amino-acid cation" ; rdfs:subClassOf obo:CHEBI_33702 . obo:CHEBI_33704 obo:IAO_0000115 "An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.05870" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "NC([*])C(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:10208", "CHEBI:13779", "CHEBI:22442", "CHEBI:2642" ; oboInOwl:hasDbXref "KEGG:C00045", "KEGG:C05167" ; oboInOwl:hasExactSynonym "alpha-amino acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Amino acid", "Amino acids", "alpha-amino acids", "alpha-amino carboxylic acids" ; oboInOwl:id "CHEBI:33704" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-amino acid" ; rdfs:subClassOf obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_33558 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_78608 ] . obo:CHEBI_33707 obo:IAO_0000115 "A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position gamma to the carboxy group." ; oboInOwl:hasExactSynonym "gamma-amino acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gamma-amino acids" ; oboInOwl:id "CHEBI:33707" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "gamma-amino acid" ; rdfs:subClassOf obo:CHEBI_83820, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_71666 ] . obo:CHEBI_33708 obo:IAO_0000115 "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue." ; oboInOwl:hasExactSynonym "amino-acid residue" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino acid residue", "amino-acid residues" ; oboInOwl:id "CHEBI:33708" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amino-acid residue" ; rdfs:subClassOf obo:CHEBI_33247, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_33709 ] . obo:CHEBI_33709 obo:IAO_0000115 "A carboxylic acid containing one or more amino groups." ; oboInOwl:hasAlternativeId "CHEBI:13815", "CHEBI:22477" ; oboInOwl:hasDbXref "Wikipedia:Amino_acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aminocarbonsaeure", "Aminokarbonsaeure", "Aminosaeure", "amino acids" ; oboInOwl:id "CHEBI:33709" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amino acid" ; rdfs:subClassOf obo:CHEBI_33575, obo:CHEBI_50047, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_37022 ] . obo:CHEBI_33719 oboInOwl:hasExactSynonym "alpha-amino-acid cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-amino acid cations", "alpha-amino-acid cations" ; oboInOwl:id "CHEBI:33719" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-amino-acid cation" ; rdfs:subClassOf obo:CHEBI_33703 . obo:CHEBI_33744 oboInOwl:hasExactSynonym "iron group molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iron group molecular entities" ; oboInOwl:id "CHEBI:33744" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iron group molecular entity" ; rdfs:subClassOf obo:CHEBI_33676, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33356 ] . obo:CHEBI_33745 oboInOwl:hasExactSynonym "copper group molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "copper group molecular entities" ; oboInOwl:id "CHEBI:33745" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "copper group molecular entity" ; rdfs:subClassOf obo:CHEBI_33676, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_33366 ] . obo:CHEBI_33791 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical nucleoside residues", "common nucleoside residues", "nucleoside residue", "standard nucleoside residues" ; oboInOwl:id "CHEBI:33791" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "canonical nucleoside residue" ; rdfs:subClassOf obo:CHEBI_50320 . obo:CHEBI_33792 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N", "Nuc", "canonical ribonucleoside residues", "common ribonucleoside residue", "common ribonucleoside residues", "standard ribonucleoside residues" ; oboInOwl:id "CHEBI:33792" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "canonical ribonucleoside residue" ; rdfs:subClassOf obo:CHEBI_33791 . obo:CHEBI_33822 obo:IAO_0000115 "An organic compound having at least one hydroxy group attached to a carbon atom." ; oboInOwl:hasAlternativeId "CHEBI:64710" ; oboInOwl:hasExactSynonym "hydroxy compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic alcohol", "organic hydroxy compounds" ; oboInOwl:id "CHEBI:33822" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic hydroxy compound" ; rdfs:subClassOf obo:CHEBI_24651, obo:CHEBI_50860 . obo:CHEBI_33832 obo:IAO_0000115 "Any organic molecule that consists of atoms connected in the form of a ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic cyclic compounds" ; oboInOwl:id "CHEBI:33832" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic cyclic compound" ; rdfs:subClassOf obo:CHEBI_33595, obo:CHEBI_72695 . obo:CHEBI_33833 obo:IAO_0000115 "A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2)." ; oboInOwl:hasExactSynonym "heteroarenes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hetarenes" ; oboInOwl:id "CHEBI:33833" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heteroarene" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_33659 . obo:CHEBI_33836 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "benzenoid aromatic compounds", "benzenoid compound" ; oboInOwl:id "CHEBI:33836" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "benzenoid aromatic compound" ; rdfs:subClassOf obo:CHEBI_33598, obo:CHEBI_33659 . obo:CHEBI_33838 obo:IAO_0000115 "An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents." ; chebi:charge "0" ; chebi:formula "C5H8O3R2" ; chebi:mass "116.115" ; chebi:monoisotopicmass "116.04734" ; chebi:smiles "[C@H]1([C@H]([C@@H](*)[C@@H](O1)*)O)CO" ; oboInOwl:hasAlternativeId "CHEBI:13661", "CHEBI:25611", "CHEBI:7647" ; oboInOwl:hasDbXref "KEGG:C00801", "Wikipedia:Nucleoside" ; oboInOwl:hasExactSynonym "Nucleoside", "nucleosides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a nucleoside", "nucleosides" ; oboInOwl:id "CHEBI:33838" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside" ; rdfs:subClassOf obo:CHEBI_21731, obo:CHEBI_26912, obo:CHEBI_61120 . obo:CHEBI_33839 obo:IAO_0000115 "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasDbXref "Wikipedia:Macromolecule" ; oboInOwl:hasExactSynonym "macromolecule" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "macromolecules", "polymer", "polymer molecule", "polymers" ; oboInOwl:id "CHEBI:33839" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "macromolecule" ; rdfs:subClassOf obo:CHEBI_36357 . obo:CHEBI_33848 obo:IAO_0000115 "A polycyclic aromatic hydrocarbon." ; oboInOwl:hasDbXref "PMID:15198916", "PMID:25679824", "Wikipedia:Polycyclic_aromatic_hydrocarbon" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "PAH", "PAHs", "polycyclic arenes", "polycyclic aromatic hydrocarbons" ; oboInOwl:id "CHEBI:33848" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polycyclic arene" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33658, obo:CHEBI_33666, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_138015 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50903 ] . obo:CHEBI_33853 obo:IAO_0000115 "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring." ; chebi:charge "0" ; chebi:formula "C6HOR5" ; chebi:mass "89.072" ; chebi:monoisotopicmass "89.00274" ; chebi:smiles "C1(=C(C(=C(C(=C1*)*)*)*)*)O" ; oboInOwl:hasAlternativeId "CHEBI:13664", "CHEBI:13825", "CHEBI:25969", "CHEBI:2857" ; oboInOwl:hasDbXref "KEGG:C15584", "MetaCyc:Phenols", "Wikipedia:Phenols" ; oboInOwl:hasExactSynonym "phenols" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aryl alcohol", "a phenol", "arenols" ; oboInOwl:id "CHEBI:33853" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phenols" ; rdfs:subClassOf obo:CHEBI_33659, obo:CHEBI_33822 . obo:CHEBI_33855 obo:IAO_0000115 "Any aldehyde in which the carbonyl group is attached to an aromatic moiety." ; chebi:charge "0" ; chebi:formula "CHOR" ; chebi:mass "29.018" ; chebi:monoisotopicmass "29.00274" ; chebi:smiles "*C(=O)[H]" ; oboInOwl:hasAlternativeId "CHEBI:13819", "CHEBI:22621", "CHEBI:2832", "CHEBI:87908" ; oboInOwl:hasDbXref "KEGG:C00193", "MetaCyc:Aryl-Aldehyde" ; oboInOwl:hasExactSynonym "arenecarbaldehyde" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aromatic aldehyde", "an aromatic aldehyde", "arenecarbaldehydes", "aryl aldehyde", "aryl aldehydes" ; oboInOwl:id "CHEBI:33855" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "arenecarbaldehyde" ; rdfs:subClassOf obo:CHEBI_17478, obo:CHEBI_33659 . obo:CHEBI_33860 obo:IAO_0000115 "An amino compound in which the amino group is linked directly to an aromatic system." ; oboInOwl:hasAlternativeId "CHEBI:13827", "CHEBI:22622", "CHEBI:22646", "CHEBI:2834", "CHEBI:2863" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aromatic amines", "aryl amine", "aryl amines", "arylamine", "arylamines" ; oboInOwl:id "CHEBI:33860" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aromatic amine" ; rdfs:subClassOf obo:CHEBI_33659, obo:CHEBI_50047 . obo:CHEBI_33861 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "transition element coordination entities", "transition metal coordination compounds", "transition metal coordination entities" ; oboInOwl:id "CHEBI:33861" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "transition element coordination entity" ; rdfs:subClassOf obo:CHEBI_33240, obo:CHEBI_33497 . obo:CHEBI_33892 oboInOwl:hasExactSynonym "iron coordination entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iron coordination compounds", "iron coordination entities" ; oboInOwl:id "CHEBI:33892" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iron coordination entity" ; rdfs:subClassOf obo:CHEBI_24873, obo:CHEBI_33861 . obo:CHEBI_33893 obo:IAO_0000115 "A substance used in a chemical reaction to detect, measure, examine, or produce other substances." ; oboInOwl:hasExactSynonym "reagent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "reactif", "reactivo", "reagents" ; oboInOwl:id "CHEBI:33893" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "reagent" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_33909 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metal-tetrapyrrole", "metal-tetrapyrrole complex", "metallotetrapyrroles" ; oboInOwl:id "CHEBI:33909" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "metallotetrapyrrole" ; rdfs:subClassOf obo:CHEBI_36309 . obo:CHEBI_33916 obo:IAO_0000115 "A pentose with a (potential) aldehyde group at one end." ; oboInOwl:hasDbXref "PMID:10723607" ; oboInOwl:hasExactSynonym "aldopentose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldopentoses" ; oboInOwl:id "CHEBI:33916" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aldopentose" ; rdfs:subClassOf obo:CHEBI_15693, obo:CHEBI_25901 . obo:CHEBI_33917 obo:IAO_0000115 "A hexose with a (potential) aldehyde group at one end." ; oboInOwl:hasAlternativeId "CHEBI:2558" ; oboInOwl:hasExactSynonym "aldohexose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldohexoses" ; oboInOwl:id "CHEBI:33917" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aldohexose" ; rdfs:subClassOf obo:CHEBI_15693, obo:CHEBI_18133 . obo:CHEBI_33937 obo:IAO_0000115 "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "macronutrients" ; oboInOwl:id "CHEBI:33937" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "macronutrient" ; rdfs:subClassOf obo:CHEBI_33284 . obo:CHEBI_33942 obo:IAO_0000115 "Any aldopentose where the open-chain form has all the hydroxy groups on the same side in the Fischer projection. Occurrs in two enantiomeric forms, D- and L-ribose, of which only the former is found in nature." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:mass "150.130" ; chebi:monoisotopicmass "150.05282" ; oboInOwl:hasAlternativeId "CHEBI:26564" ; oboInOwl:hasExactSynonym "ribo-pentose", "ribose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Rib" ; oboInOwl:id "CHEBI:33942" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribose" ; rdfs:subClassOf obo:CHEBI_33916 . obo:CHEBI_33958 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halide salts", "halides" ; oboInOwl:id "CHEBI:33958" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halide salt" ; rdfs:subClassOf obo:CHEBI_24866, obo:CHEBI_37578, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_16042 ] . obo:CHEBI_33964 oboInOwl:hasExactSynonym "silver molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "silver compounds", "silver molecular entities" ; oboInOwl:id "CHEBI:33964" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "silver molecular entity" ; rdfs:subClassOf obo:CHEBI_33745, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_30512 ] . obo:CHEBI_33966 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:33966" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental silver" ; rdfs:subClassOf obo:CHEBI_33964 . obo:CHEBI_34905 obo:IAO_0000115 "An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions." ; chebi:charge "+2" ; chebi:formula "C12H14N2" ; chebi:inchi "InChI=1S/C12H14N2/c1-13-7-3-11(4-8-13)12-5-9-14(2)10-6-12/h3-10H,1-2H3/q+2" ; chebi:inchikey "INFDPOAKFNIJBF-UHFFFAOYSA-N" ; chebi:mass "186.25304" ; chebi:monoisotopicmass "186.11460" ; chebi:smiles "C[n+]1ccc(cc1)-c1cc[n+](C)cc1" ; oboInOwl:hasDbXref "Beilstein:3590305", "CAS:4685-14-7", "Chemspider:15147", "FooDB:FDB011120", "Gmelin:51125", "KEGG:C14701", "PMID:11349957", "PMID:18620719", "PMID:20377249", "PMID:20582739", "PMID:21151885", "PMID:21236547", "PMID:21300143", "PMID:21318114", "PMID:21429624", "PMID:21493003", "PMID:21598522", "PMID:21616728", "PMID:21619794", "PMID:21619822", "PMID:21750730", "PMID:21777615", "PMID:21787677", "PMID:21802509", "PPDB:505", "Pesticides:paraquat", "Reaxys:3590305" ; oboInOwl:hasExactSynonym "1,1'-dimethyl-[4,4'-bipyridin]-1,1'-diium", "Paraquat" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1'-Dimethyl-4,4'-bipyridinium", "1,1'-dimethyl-4,4'-bipyridyldiylium", "N,N'-dimethyl-4,4'-bipyridinium", "N,N'-dimethyl-4,4'-bipyridinium dication", "dimethyl viologen", "methyl viologen ion(2+)", "paraquat dication", "paraquat ion" ; oboInOwl:id "CHEBI:34905" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "paraquat" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25697, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24527 ], [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_30985 ] . obo:CHEBI_350546 obo:IAO_0000115 "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C10H13N2O" ; chebi:inchi "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1" ; chebi:inchikey "QZAYGJVTTNCVMB-UHFFFAOYSA-O" ; chebi:mass "177.22250" ; chebi:monoisotopicmass "177.10224" ; chebi:smiles "[NH3+]CCc1c[nH]c2ccc(O)cc12" ; oboInOwl:hasExactSynonym "2-(5-hydroxy-1H-indol-3-yl)ethanaminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "serotonin", "serotonin cation" ; oboInOwl:id "CHEBI:350546" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "serotonin(1+)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_28790 ] . obo:CHEBI_35106 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nitrogen hydrides" ; oboInOwl:id "CHEBI:35106" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nitrogen hydride" ; rdfs:subClassOf obo:CHEBI_35881, obo:CHEBI_51143 . obo:CHEBI_35107 obo:IAO_0000115 "Saturated acyclic nitrogen hydrides having the general formula NnHn+2." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "azanes" ; oboInOwl:id "CHEBI:35107" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "azane" ; rdfs:subClassOf obo:CHEBI_35106 . obo:CHEBI_35131 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aldose phosphates" ; oboInOwl:id "CHEBI:35131" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aldose phosphate" ; rdfs:subClassOf obo:CHEBI_33447 . obo:CHEBI_35155 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35155" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental calcium" ; rdfs:subClassOf obo:CHEBI_22985 . obo:CHEBI_35186 obo:IAO_0000115 "A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]." ; oboInOwl:hasExactSynonym "terpene", "terpenes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Terpen", "terpenes", "terpeno", "terpenos" ; oboInOwl:id "CHEBI:35186" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "terpene" ; rdfs:subClassOf obo:CHEBI_24632, obo:CHEBI_24913 . obo:CHEBI_35190 obo:IAO_0000115 "A C20 terpene." ; oboInOwl:hasExactSynonym "diterpenes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Diterpen", "diterpenes", "diterpeno", "diterpenos" ; oboInOwl:id "CHEBI:35190" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diterpene" ; rdfs:subClassOf obo:CHEBI_35186 . obo:CHEBI_35195 obo:IAO_0000115 "A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces." ; oboInOwl:hasExactSynonym "surfactant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "surface active agent", "surfactants" ; oboInOwl:id "CHEBI:35195" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "surfactant" ; rdfs:subClassOf obo:CHEBI_63046 . obo:CHEBI_35221 obo:IAO_0000115 "A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization." ; oboInOwl:hasDbXref "Wikipedia:Antimetabolite" ; oboInOwl:hasExactSynonym "antimetabolite" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimetabolites" ; oboInOwl:id "CHEBI:35221" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimetabolite" ; rdfs:subClassOf obo:CHEBI_52206 . obo:CHEBI_35222 obo:IAO_0000115 "A substance that diminishes the rate of a chemical reaction." ; oboInOwl:hasExactSynonym "inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inhibidor", "inhibiteur", "inhibitors" ; oboInOwl:id "CHEBI:35222" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inhibitor" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_35230 obo:IAO_0000115 "A fuel such as coal, oil and natural gas which has formed over many years through the decomposition of deposited vegetation which was under extreme pressure of an overburden of earth." ; oboInOwl:hasExactSynonym "fossil fuel" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35230" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fossil fuel" ; rdfs:subClassOf obo:CHEBI_33292 . obo:CHEBI_35235 chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1" ; chebi:inchikey "XUJNEKJLAYXESH-REOHCLBHSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "[NH3+][C@@H](CS)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:49993" ; oboInOwl:hasExactSynonym "(2R)-2-ammonio-3-sulfanylpropanoate", "L-cysteine zwitterion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2R)-2-ammonio-3-mercaptopropanoate", "L-cysteine" ; oboInOwl:id "CHEBI:35235" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-cysteine zwitterion" ; rdfs:subClassOf obo:CHEBI_35237, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32442 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32445 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_35236 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17561 ] . obo:CHEBI_35236 chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m1/s1" ; chebi:inchikey "XUJNEKJLAYXESH-UWTATZPHSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "[NH3+][C@H](CS)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:2352354" ; oboInOwl:hasExactSynonym "(2S)-2-ammonio-3-sulfanylpropanoate", "D-cysteine zwitterion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2S)-2-ammonio-3-mercaptopropanoate", "D-cysteine" ; oboInOwl:id "CHEBI:35236" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-cysteine zwitterion" ; rdfs:subClassOf obo:CHEBI_35237, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32449 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32451 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_35235 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16375 ] . obo:CHEBI_35237 chebi:charge "0" ; chebi:formula "C3H7NO2S" ; chebi:inchi "InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)" ; chebi:inchikey "XUJNEKJLAYXESH-UHFFFAOYSA-N" ; chebi:mass "121.15922" ; chebi:monoisotopicmass "121.01975" ; chebi:smiles "[NH3+]C(CS)C([O-])=O" ; oboInOwl:hasDbXref "Gmelin:49992" ; oboInOwl:hasExactSynonym "2-ammonio-3-sulfanylpropanoate", "cysteine zwitterion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)H3N-CH(CH2SH)-COO(-)", "2-ammonio-3-mercaptopropanoate" ; oboInOwl:id "CHEBI:35237" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cysteine zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_32456 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_32458 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_15356 ] . obo:CHEBI_35238 obo:IAO_0000115 "The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group." ; oboInOwl:hasExactSynonym "amino acid zwitterion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35238" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_27369 . obo:CHEBI_35267 obo:IAO_0000115 "A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." ; chebi:charge "+1" ; chebi:formula "NR4" ; chebi:mass "14.00670" ; chebi:monoisotopicmass "14.00307" ; chebi:smiles "[*][N+]([*])([*])[*]" ; oboInOwl:hasAlternativeId "CHEBI:26470", "CHEBI:8693" ; oboInOwl:hasDbXref "KEGG:C06703" ; oboInOwl:hasExactSynonym "quaternary ammonium ion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Quaternary amine", "a quaternary ammonium", "quaternary ammonium ions" ; oboInOwl:id "CHEBI:35267" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "quaternary ammonium ion" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274 . obo:CHEBI_35273 obo:IAO_0000115 "Derivatives of ammonium compounds, (NH4(+))Y(-), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups." ; oboInOwl:hasAlternativeId "CHEBI:26468", "CHEBI:35268" ; oboInOwl:hasExactSynonym "quaternary ammonium compounds", "quaternary ammonium salt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "quaternary ammonium compound", "quaternary ammonium salts" ; oboInOwl:id "CHEBI:35273" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "quaternary ammonium salt" ; rdfs:subClassOf obo:CHEBI_26469, obo:CHEBI_46850 . obo:CHEBI_35274 obo:IAO_0000115 "A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ammonium ion derivatives", "azanium ion derivative", "azanium ion derivatives" ; oboInOwl:id "CHEBI:35274" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ammonium ion derivative" ; rdfs:subClassOf obo:CHEBI_33702, obo:CHEBI_51143, [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_28938 ] . obo:CHEBI_35276 obo:IAO_0000115 "Compounds (NH4(+))Y(-) and derivatives, in which one or more of the hydrogens bonded to nitrogen have been replaced with univalent groups." ; oboInOwl:hasExactSynonym "azanium compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ammonium compounds" ; oboInOwl:id "CHEBI:35276" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ammonium compound" ; rdfs:subClassOf obo:CHEBI_51143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_35274 ] . obo:CHEBI_35287 obo:IAO_0000115 "A choline ester formed from choline and a carboxylic acid." ; chebi:charge "+1" ; chebi:formula "C6H13NO2R" ; chebi:mass "131.17290" ; chebi:monoisotopicmass "131.09463" ; chebi:smiles "C[N+](C)(C)CCOC([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13245", "CHEBI:22227", "CHEBI:2463" ; oboInOwl:hasDbXref "KEGG:C01777" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acylcholines", "an acylcholine" ; oboInOwl:id "CHEBI:35287" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acylcholine" ; rdfs:subClassOf obo:CHEBI_35267 . obo:CHEBI_35293 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fused compounds", "fused polycyclic compounds", "fused-ring polycyclic compound", "fused-ring polycyclic compounds", "polycyclic fused-ring compounds" ; oboInOwl:id "CHEBI:35293" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fused compound" ; rdfs:subClassOf obo:CHEBI_33635 . obo:CHEBI_35294 obo:IAO_0000115 "A polyclic compound in which all of the ring members are carbon atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbopolycyclic compounds" ; oboInOwl:id "CHEBI:35294" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbopolycyclic compound" ; rdfs:subClassOf obo:CHEBI_33598, obo:CHEBI_35295 . obo:CHEBI_35295 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "homopolycyclic compounds" ; oboInOwl:id "CHEBI:35295" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "homopolycyclic compound" ; rdfs:subClassOf obo:CHEBI_33597, obo:CHEBI_33635 . obo:CHEBI_35300 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ortho- and peri-fused polycyclic arenes" ; oboInOwl:id "CHEBI:35300" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ortho- and peri-fused polycyclic arene" ; rdfs:subClassOf obo:CHEBI_33639, obo:CHEBI_33848 . obo:CHEBI_35315 oboInOwl:hasExactSynonym "deoxy hexoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "deoxy hexosides" ; oboInOwl:id "CHEBI:35315" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "deoxy hexoside" ; rdfs:subClassOf obo:CHEBI_24400 . obo:CHEBI_3533 obo:IAO_0000115 "A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions." ; chebi:charge "0" ; chebi:formula "C28H38N2O4" ; chebi:inchi "InChI=1S/C28H38N2O4/c1-5-17-16-30-9-7-19-13-27(33-3)28(34-4)15-22(19)24(30)11-20(17)10-23-21-14-26(32-2)25(31)12-18(21)6-8-29-23/h12-15,17,20,23-24,29,31H,5-11,16H2,1-4H3/t17-,20-,23+,24-/m0/s1" ; chebi:inchikey "DTGZHCFJNDAHEN-OZEXIGSWSA-N" ; chebi:mass "466.61240" ; chebi:monoisotopicmass "466.28316" ; chebi:smiles "[H][C@]1(C[C@@]2([H])NCCc3cc(O)c(OC)cc23)C[C@]2([H])N(CCc3cc(OC)c(OC)cc23)C[C@@H]1CC" ; oboInOwl:hasDbXref "Beilstein:100615", "CAS:483-17-0", "KEGG:C09390", "KNApSAcK:C00001835", "LINCS:LSM-3808", "PMID:11411558", "PMID:11913711", "PMID:11996324", "PMID:12880315", "PMID:13437707", "PMID:18327911", "PMID:20061395", "PMID:20495341", "PMID:21228475", "PMID:2715231", "PMID:6716976", "Reaxys:100615" ; oboInOwl:hasExactSynonym "7',10,11-trimethoxyemetan-6'-ol", "Cephaeline" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Cephaelin" ; oboInOwl:id "CHEBI:3533" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cephaeline" ; rdfs:subClassOf obo:CHEBI_61692, [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_36380 ] . obo:CHEBI_35337 obo:IAO_0000115 "Any drug that enhances the activity of the central nervous system." ; oboInOwl:hasDbXref "Wikipedia:Central_nervous_system_stimulants" ; oboInOwl:hasExactSynonym "central nervous system stimulant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CNS stimulant", "analeptic", "analeptic agent", "analeptic drug", "analeptics", "central stimulant" ; oboInOwl:id "CHEBI:35337" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "central nervous system stimulant" ; rdfs:subClassOf obo:CHEBI_35470 . obo:CHEBI_35341 obo:IAO_0000115 "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene." ; chebi:charge "0" ; chebi:formula "C19H31R" ; chebi:mass "259.450" ; chebi:monoisotopicmass "259.24258" ; chebi:smiles "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCCC4)C" ; oboInOwl:hasAlternativeId "CHEBI:13687", "CHEBI:26768", "CHEBI:9263" ; oboInOwl:hasDbXref "KEGG:C00377", "MetaCyc:Steroids" ; oboInOwl:hasExactSynonym "Steroid", "steroids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a steroid" ; oboInOwl:id "CHEBI:35341" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "steroid" ; rdfs:subClassOf obo:CHEBI_18059, obo:CHEBI_51958 . obo:CHEBI_35350 oboInOwl:hasAlternativeId "CHEBI:24748", "CHEBI:5814" ; oboInOwl:hasDbXref "KEGG:C02159" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Hydroxysteroid", "hydroxy steroids", "hydroxysteroids" ; oboInOwl:id "CHEBI:35350" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_33822, obo:CHEBI_35341 . obo:CHEBI_35352 obo:IAO_0000115 "Any heteroorganic entity containing at least one carbon-nitrogen bond." ; oboInOwl:hasExactSynonym "organonitrogen compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organonitrogens" ; oboInOwl:id "CHEBI:35352" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organonitrogen compound" ; rdfs:subClassOf obo:CHEBI_33285, obo:CHEBI_51143 . obo:CHEBI_35356 obo:IAO_0000115 "An imide in which the two acyl substituents on nitrogen are carboacyl groups." ; chebi:charge "0" ; chebi:formula "C2NO2R3" ; chebi:mass "70.027" ; chebi:monoisotopicmass "69.99290" ; chebi:smiles "[*]N(C([*])=O)C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dicarboximides" ; oboInOwl:id "CHEBI:35356" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dicarboximide" ; rdfs:subClassOf obo:CHEBI_24782 . obo:CHEBI_35366 obo:IAO_0000115 "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids." ; chebi:charge "0" ; chebi:formula "CHO2R" ; chebi:mass "45.01740" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "OC([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13633", "CHEBI:24024", "CHEBI:4984" ; oboInOwl:hasDbXref "KEGG:C00162", "PMID:14287444", "PMID:14300208", "PMID:14328676", "Wikipedia:Fatty_acid" ; oboInOwl:hasExactSynonym "Fatty acid", "fatty acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Fettsaeure", "Fettsaeuren", "acide gras", "acides gras", "acido graso", "acidos grasos", "fatty acids" ; oboInOwl:id "CHEBI:35366" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fatty acid" ; rdfs:subClassOf obo:CHEBI_18059, obo:CHEBI_25384, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_28868 ] . obo:CHEBI_35367 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "thiocarboxylates", "thiocarboxylic acid anions" ; oboInOwl:id "CHEBI:35367" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "thiocarboxylic acid anion" ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_35381 obo:IAO_0000115 "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group." ; oboInOwl:hasAlternativeId "CHEBI:25407", "CHEBI:6984" ; oboInOwl:hasDbXref "KEGG:C06698" ; oboInOwl:hasExactSynonym "Monosaccharide", "monosaccharides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Monosaccharid", "Monosacharid", "monosacarido", "monosacaridos" ; oboInOwl:id "CHEBI:35381" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monosaccharide" ; rdfs:subClassOf obo:CHEBI_16646 . obo:CHEBI_35406 obo:IAO_0000115 "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen." ; oboInOwl:hasAlternativeId "CHEBI:33274", "CHEBI:33436" ; oboInOwl:hasExactSynonym "oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxoacid anions", "oxoanions" ; oboInOwl:id "CHEBI:35406" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxoanion" ; rdfs:subClassOf obo:CHEBI_25741, obo:CHEBI_33273 . obo:CHEBI_35441 obo:IAO_0000115 "A substance used in the prophylaxis or therapy of infectious diseases." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-infective agents", "anti-infective drugs", "antiinfective agents", "antiinfective drug" ; oboInOwl:id "CHEBI:35441" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antiinfective agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35442 obo:IAO_0000115 "A substance used to treat or prevent parasitic infections." ; oboInOwl:hasDbXref "Wikipedia:Antiparasitic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antiparasitic drugs", "antiparasitics", "parasiticides" ; oboInOwl:id "CHEBI:35442" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antiparasitic agent" ; rdfs:subClassOf obo:CHEBI_35441 . obo:CHEBI_35443 obo:IAO_0000115 "Substance intended to kill parasitic worms (helminths)." ; oboInOwl:hasExactSynonym "anthelminthic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anthelminthics", "anthelmintic", "anthelmintics", "antihelminth", "antihelmintico", "vermifuge" ; oboInOwl:id "CHEBI:35443" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anthelminthic drug" ; rdfs:subClassOf obo:CHEBI_35442 . obo:CHEBI_35444 obo:IAO_0000115 "A substance used in the treatment or control of nematode infestations." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antinematodal agent", "antinematodal drugs", "antinematodals" ; oboInOwl:id "CHEBI:35444" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antinematodal drug" ; rdfs:subClassOf obo:CHEBI_25491, obo:CHEBI_35443 . obo:CHEBI_35469 obo:IAO_0000115 "Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antidepressant drugs", "antidepressants", "thymoanaleptics", "thymoleptic drugs", "thymoleptics" ; oboInOwl:id "CHEBI:35469" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antidepressant" ; rdfs:subClassOf obo:CHEBI_35471 . obo:CHEBI_35470 obo:IAO_0000115 "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CNS agent", "CNS drugs", "central nervous system agents" ; oboInOwl:id "CHEBI:35470" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "central nervous system drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35471 obo:IAO_0000115 "A loosely defined grouping of drugs that have effects on psychological function." ; oboInOwl:hasDbXref "Wikipedia:Psychotropic_drug" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "psychoactive agent", "psychoactive drugs", "psychopharmaceuticals", "psychotropic drugs" ; oboInOwl:id "CHEBI:35471" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "psychotropic drug" ; rdfs:subClassOf obo:CHEBI_35470 . obo:CHEBI_35473 obo:IAO_0000115 "A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ataractics", "tranquilising drug", "tranquilizing drugs", "tranquillising agent", "tranquillizing agents" ; oboInOwl:id "CHEBI:35473" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tranquilizing drug" ; rdfs:subClassOf obo:CHEBI_35471, obo:CHEBI_35488 . obo:CHEBI_35474 obo:IAO_0000115 "Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-anxiety agents", "anti-anxiety drugs", "anxiolytic agents", "anxiolytics", "minor tranquilisers", "minor tranquilizers", "minor tranquilizing agents" ; oboInOwl:id "CHEBI:35474" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anxiolytic drug" ; rdfs:subClassOf obo:CHEBI_35473 . obo:CHEBI_35476 obo:IAO_0000115 "Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Neuroleptikum", "antipsychotic agents", "antipsychotic drug", "antipsychotic drugs", "antipsychotics", "antipsychotiques", "grosser Tranquilizer", "major tranquilizers", "major tranquilizing agents", "neuroleptic", "neuroleptic agents", "neuroleptics", "neuroleptique", "neuroleptiques" ; oboInOwl:id "CHEBI:35476" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antipsychotic agent" ; rdfs:subClassOf obo:CHEBI_35473 . obo:CHEBI_35479 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkali metal salts" ; oboInOwl:id "CHEBI:35479" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkali metal salt" ; rdfs:subClassOf obo:CHEBI_24866, obo:CHEBI_33296 . obo:CHEBI_35480 obo:IAO_0000115 "An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35480" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "analgesic" ; rdfs:subClassOf obo:CHEBI_23888, obo:CHEBI_52210 . obo:CHEBI_35481 obo:IAO_0000115 "A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35481" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "non-narcotic analgesic" ; rdfs:subClassOf obo:CHEBI_35480 . obo:CHEBI_35488 obo:IAO_0000115 "A loosely defined group of drugs that tend to reduce the activity of the central nervous system." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CNS depressants", "central nervous system depressants" ; oboInOwl:id "CHEBI:35488" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "central nervous system depressant" ; rdfs:subClassOf obo:CHEBI_35470 . obo:CHEBI_35498 obo:IAO_0000115 "An agent that promotes the excretion of urine through its effects on kidney function." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "diuretics" ; oboInOwl:id "CHEBI:35498" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diuretic" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35506 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkaloid fundamental parents" ; oboInOwl:id "CHEBI:35506" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35507 . obo:CHEBI_35507 oboInOwl:hasExactSynonym "natural product fundamental parents" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35507" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "natural product fundamental parent" ; rdfs:subClassOf obo:CHEBI_33245 . obo:CHEBI_35522 obo:IAO_0000115 "An agent that selectively binds to and activates beta-adrenergic receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "beta-adrenergic agonists", "beta-adrenergic receptor agonist", "beta-adrenoceptor agonists" ; oboInOwl:id "CHEBI:35522" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "beta-adrenergic agonist" ; rdfs:subClassOf obo:CHEBI_37886, obo:CHEBI_48540 . obo:CHEBI_35524 obo:IAO_0000115 "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sympathomimetic", "sympathomimetics" ; oboInOwl:id "CHEBI:35524" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sympathomimetic agent" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_35545 chebi:charge "0" ; chebi:formula "C10H8N2" ; chebi:mass "156.184" ; chebi:monoisotopicmass "156.06875" ; oboInOwl:hasExactSynonym "bipyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bipyridin", "bipyridyl" ; oboInOwl:id "CHEBI:35545" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bipyridine" ; rdfs:subClassOf obo:CHEBI_50511 . obo:CHEBI_35552 oboInOwl:hasExactSynonym "heterocyclic parent hydrides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterocyclic fundamental parent", "heterocyclic organic fundamental parents", "organic heterocyclic fundamental parents" ; oboInOwl:id "CHEBI:35552" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heterocyclic organic fundamental parent" ; rdfs:subClassOf obo:CHEBI_33245 . obo:CHEBI_35554 obo:IAO_0000115 "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cardiovascular agent", "cardiovascular drugs" ; oboInOwl:id "CHEBI:35554" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cardiovascular drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35555 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude organic heteromonocyclic parents", "mancude-ring organic heteromonocyclic parents" ; oboInOwl:id "CHEBI:35555" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mancude organic heteromonocyclic parent" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_35571 . obo:CHEBI_35568 obo:IAO_0000115 "Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds." ; oboInOwl:hasExactSynonym "mancude-ring systems" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude rings", "mancunide-ring systems" ; oboInOwl:id "CHEBI:35568" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mancude ring" ; rdfs:subClassOf obo:CHEBI_23367 . obo:CHEBI_35570 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude organic heterobicyclic parents", "mancude-ring organic heterobicyclic parents" ; oboInOwl:id "CHEBI:35570" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mancude organic heterobicyclic parent" ; rdfs:subClassOf obo:CHEBI_27171, obo:CHEBI_35571 . obo:CHEBI_35571 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude organic heterocyclic parents", "mancude-ring organic heterocyclic parents" ; oboInOwl:id "CHEBI:35571" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mancude organic heterocyclic parent" ; rdfs:subClassOf obo:CHEBI_35552, obo:CHEBI_35573 . obo:CHEBI_35573 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic mancude parents", "organic mancude-ring parents" ; oboInOwl:id "CHEBI:35573" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic mancude parent" ; rdfs:subClassOf obo:CHEBI_33245, obo:CHEBI_35568 . obo:CHEBI_35584 obo:IAO_0000115 "A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:mass "120.112" ; chebi:monoisotopicmass "120.04360" ; oboInOwl:hasDbXref "HMDB:HMDB0001366", "KEGG:C15587", "MetaCyc:PURINE", "PMID:12865945", "PMID:24088627" ; oboInOwl:hasExactSynonym "purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35584" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_26401, obo:CHEBI_35570, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ] . obo:CHEBI_35586 obo:IAO_0000115 "The 1H-tautomer of purine." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" ; chebi:inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" ; chebi:mass "120.11210" ; chebi:monoisotopicmass "120.04360" ; chebi:smiles "c1nc2c[nH]cnc2n1" ; oboInOwl:hasDbXref "Gmelin:2379911" ; oboInOwl:hasExactSynonym "1H-purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35586" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "1H-purine" ; rdfs:subClassOf obo:CHEBI_35584, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17258 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35588 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_35588 obo:IAO_0000115 "The 3H-tautomer of purine." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" ; chebi:inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" ; chebi:mass "120.11222" ; chebi:monoisotopicmass "120.04360" ; chebi:smiles "c1nc2cnc[nH]c2n1" ; oboInOwl:hasDbXref "PMID:6149478", "PMID:7178185", "PMID:7296170", "Reaxys:1210196" ; oboInOwl:hasExactSynonym "3H-purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35588" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "3H-purine" ; rdfs:subClassOf obo:CHEBI_35584, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17258 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35586 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35589 ] . obo:CHEBI_35589 obo:IAO_0000115 "The 9H-tautomer of purine." ; chebi:charge "0" ; chebi:formula "C5H4N4" ; chebi:inchi "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)" ; chebi:inchikey "KDCGOANMDULRCW-UHFFFAOYSA-N" ; chebi:mass "120.11222" ; chebi:monoisotopicmass "120.04360" ; chebi:smiles "c1ncc2nc[nH]c2n1" ; oboInOwl:hasDbXref "Beilstein:606899", "CAS:120-73-0", "Gmelin:3120", "Wikipedia:Purine" ; oboInOwl:hasExactSynonym "9H-purine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35589" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "9H-purine" ; rdfs:subClassOf obo:CHEBI_35584, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17258 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35586 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_35588 ] . obo:CHEBI_35604 obo:IAO_0000115 "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n." ; oboInOwl:hasExactSynonym "carbon oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon oxoanions", "oxocarbon anion", "oxocarbon anions" ; oboInOwl:id "CHEBI:35604" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbon oxoanion" ; rdfs:subClassOf obo:CHEBI_25696, obo:CHEBI_35406, obo:CHEBI_36963 . obo:CHEBI_35605 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbon oxoacids", "oxoacids of carbon" ; oboInOwl:id "CHEBI:35605" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbon oxoacid" ; rdfs:subClassOf obo:CHEBI_24833, obo:CHEBI_36963 . obo:CHEBI_35610 obo:IAO_0000115 "A substance that inhibits or prevents the proliferation of neoplasms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anticancer agent", "anticancer agents", "antineoplastic", "antineoplastic agents", "cytostatic" ; oboInOwl:id "CHEBI:35610" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antineoplastic agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35618 obo:IAO_0000115 "Any ether in which the oxygen is attached to at least one aryl substituent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35618" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aromatic ether" ; rdfs:subClassOf obo:CHEBI_25698, obo:CHEBI_33659 . obo:CHEBI_35620 obo:IAO_0000115 "A drug used to cause dilation of the blood vessels." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "vasodilator", "vasodilator agents" ; oboInOwl:id "CHEBI:35620" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "vasodilator agent" ; rdfs:subClassOf obo:CHEBI_35554 . obo:CHEBI_35623 obo:IAO_0000115 "A drug used to prevent seizures or reduce their severity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Antiepileptika", "Antiepileptikum", "Antikonvulsiva", "Antikonvulsivum", "anti-convulsant", "anti-convulsants", "anti-convulsive agent", "anti-convulsive agents", "anticonvulsants", "anticonvulsive agent", "anticonvulsive agents", "antiepileptic", "antiepileptics", "antiepileptique", "antiepileptiques" ; oboInOwl:id "CHEBI:35623" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anticonvulsant" ; rdfs:subClassOf obo:CHEBI_35488 . obo:CHEBI_35640 obo:IAO_0000115 "Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ARI", "NERI", "NRI", "adrenergic reuptake inhibitor", "adrenergic reuptake inhibitors", "adrenergic uptake inhibitors", "norepinephrine reuptake inhibitor", "norepinephrine reuptake inhibitors" ; oboInOwl:id "CHEBI:35640" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adrenergic uptake inhibitor" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_35662 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "terpenoid fundamental parents" ; oboInOwl:id "CHEBI:35662" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "terpenoid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35507 . obo:CHEBI_35678 obo:IAO_0000115 "A drug that binds to and activates histamine receptors. Although they have been suggested for a variety of clinical applications, histamine agonists have so far been more widely used in research than therapeutically." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "histamine agonists" ; oboInOwl:id "CHEBI:35678" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "histamine agonist" ; rdfs:subClassOf obo:CHEBI_37957 . obo:CHEBI_35681 obo:IAO_0000115 "A secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it." ; chebi:charge "0" ; chebi:formula "CH2OR2" ; chebi:mass "30.026" ; chebi:monoisotopicmass "30.01056" ; chebi:smiles "*C(*)O" ; oboInOwl:hasAlternativeId "CHEBI:13425", "CHEBI:13686", "CHEBI:26617", "CHEBI:58662", "CHEBI:8741", "CHEBI:9077" ; oboInOwl:hasDbXref "KEGG:C00432", "KEGG:C01612" ; oboInOwl:hasExactSynonym "Secondary alcohol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "R-CHOH-R'", "a secondary alcohol", "secondary alcohols" ; oboInOwl:id "CHEBI:35681" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "secondary alcohol" ; rdfs:subClassOf obo:CHEBI_30879 . obo:CHEBI_35683 obo:IAO_0000115 "Any organic sulfide in which the sulfur is attached to at least one aromatic group." ; oboInOwl:hasExactSynonym "aryl sulfide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aryl sulfides" ; oboInOwl:id "CHEBI:35683" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aryl sulfide" ; rdfs:subClassOf obo:CHEBI_16385 . obo:CHEBI_35701 obo:IAO_0000115 "A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter." ; oboInOwl:hasAlternativeId "CHEBI:23960", "CHEBI:4859" ; oboInOwl:hasDbXref "KEGG:C00287", "Wikipedia:Ester" ; oboInOwl:hasExactSynonym "Ester" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "esters" ; oboInOwl:id "CHEBI:35701" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ester" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_35702 obo:IAO_0000115 "An ether in which the oxygen atom is linked to two ethyl groups." ; chebi:charge "0" ; chebi:formula "C4H10O" ; chebi:inchi "InChI=1S/C4H10O/c1-3-5-4-2/h3-4H2,1-2H3" ; chebi:inchikey "RTZKZFJDLAIYFH-UHFFFAOYSA-N" ; chebi:mass "74.12160" ; chebi:monoisotopicmass "74.07316" ; chebi:smiles "CCOCC" ; oboInOwl:hasAlternativeId "CHEBI:23991", "CHEBI:31565" ; oboInOwl:hasDbXref "Beilstein:1696894", "CAS:60-29-7", "Drug_Central:4417", "Gmelin:25444", "KEGG:C13240", "KEGG:D01772", "PMID:24443836", "Reaxys:1696894", "Wikipedia:Diethyl_ether" ; oboInOwl:hasExactSynonym "1,1'-oxydiethane", "Diethyl ether" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1'-oxybisethane", "3-oxapentane", "Aether", "Anesthetic ether", "Diethylaether", "Ether", "Pronarcol", "R-610", "aether", "aether pro narcosi", "diethyl oxide", "ethoxyethane", "ethyl ether", "ethyl oxide" ; oboInOwl:id "CHEBI:35702" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diethyl ether" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_134179, obo:CHEBI_25698, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38870 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48355 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_35703 obo:IAO_0000115 "A xenobiotic (Greek, xenos \"foreign\"; bios \"life\") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means." ; oboInOwl:hasAlternativeId "CHEBI:10074", "CHEBI:27333" ; oboInOwl:hasDbXref "KEGG:C06708", "Wikipedia:Xenobiotic" ; oboInOwl:hasExactSynonym "Xenobiotic", "xenobiotic", "xenobiotics" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "xenobiotic compounds" ; oboInOwl:id "CHEBI:35703" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "xenobiotic" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_35705 obo:IAO_0000115 "An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "immunosuppressant", "immunosuppressive agents", "inmunosupresor" ; oboInOwl:id "CHEBI:35705" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "immunosuppressive agent" ; rdfs:subClassOf obo:CHEBI_50846 . obo:CHEBI_35717 obo:IAO_0000115 "A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hypnotics", "hypnotics and sedatives", "sedative drug", "sedatives", "sedatives and hypnotics" ; oboInOwl:id "CHEBI:35717" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sedative" ; rdfs:subClassOf obo:CHEBI_35488 . obo:CHEBI_35718 obo:IAO_0000115 "An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antifungal", "antifungal agents", "antifungal drug", "antifungal drugs", "antifungals" ; oboInOwl:id "CHEBI:35718" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antifungal agent" ; rdfs:subClassOf obo:CHEBI_33281 . obo:CHEBI_35737 obo:IAO_0000115 "Compounds in which one oxygen of a carboxy group has been replaced by divalent sulfur; RC(=O)SH or RC(=S)OH." ; oboInOwl:hasExactSynonym "monothiocarboxylic acid", "monothiocarboxylic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monothiocarboxylic acids", "thio acid" ; oboInOwl:id "CHEBI:35737" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monothiocarboxylic acid" ; rdfs:subClassOf obo:CHEBI_33307 . obo:CHEBI_35741 obo:IAO_0000115 "Any member of the group of lipids containing a common glycerol backbone to which at least one fatty acid-derived group is attached." ; oboInOwl:hasDbXref "PMID:18606873" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glycerolipids" ; oboInOwl:id "CHEBI:35741" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glycerolipid" ; rdfs:subClassOf obo:CHEBI_18059, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17754 ] . obo:CHEBI_35757 obo:IAO_0000115 "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.01000" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasAlternativeId "CHEBI:13657", "CHEBI:25382", "CHEBI:3407" ; oboInOwl:hasDbXref "KEGG:C00060" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Carboxylate", "Monocarboxylate", "a monocarboxylate", "monocarboxylates", "monocarboxylic acid anions" ; oboInOwl:id "CHEBI:35757" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monocarboxylic acid anion" ; rdfs:subClassOf obo:CHEBI_29067, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_25384 ] . obo:CHEBI_35776 oboInOwl:hasExactSynonym "arsenic oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "arsenic oxoanions", "oxoanions of arsenic" ; oboInOwl:id "CHEBI:35776" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "arsenic oxoanion" ; rdfs:subClassOf obo:CHEBI_22632, obo:CHEBI_33459 . obo:CHEBI_35780 obo:IAO_0000115 "A phosphorus oxoanion that is the conjugate base of phosphoric acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Pi", "phosphate", "phosphate ions" ; oboInOwl:id "CHEBI:35780" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphate ion" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33461, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_26078 ] . obo:CHEBI_35790 obo:IAO_0000115 "An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom." ; oboInOwl:hasExactSynonym "oxazole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxazoles" ; oboInOwl:id "CHEBI:35790" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxazole" ; rdfs:subClassOf obo:CHEBI_38104, obo:CHEBI_68452 . obo:CHEBI_35820 obo:IAO_0000115 "Any antimicrobial drug which is used to treat or prevent protozoal infections." ; oboInOwl:hasDbXref "Wikipedia:Antiprotozoal_agent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antiprotozoal agent", "antiprotozoal agents", "antiprotozoal drugs" ; oboInOwl:id "CHEBI:35820" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antiprotozoal drug" ; rdfs:subClassOf obo:CHEBI_35442, obo:CHEBI_36043 . obo:CHEBI_35842 obo:IAO_0000115 "A drug used to treat rheumatoid arthritis." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-rheumatic drugs", "antirheumatic agent", "antirheumatic drugs" ; oboInOwl:id "CHEBI:35842" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antirheumatic drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_35845 obo:IAO_0000115 "A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gout suppressants" ; oboInOwl:id "CHEBI:35845" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "gout suppressant" ; rdfs:subClassOf obo:CHEBI_35842 . obo:CHEBI_35875 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "imidazopyrimidines" ; oboInOwl:id "CHEBI:35875" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "imidazopyrimidine" ; rdfs:subClassOf obo:CHEBI_27171, obo:CHEBI_33833, obo:CHEBI_38101 . obo:CHEBI_35881 oboInOwl:hasExactSynonym "pnictogen hydride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pnictogen hydrides" ; oboInOwl:id "CHEBI:35881" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pnictogen hydride" ; rdfs:subClassOf obo:CHEBI_33242, obo:CHEBI_33302 . obo:CHEBI_35939 obo:IAO_0000115 "A pentenoic acid having the double bond at position 2." ; chebi:charge "0" ; chebi:formula "C5H8O2" ; chebi:inchi "InChI=1S/C5H8O2/c1-2-3-4-5(6)7/h3-4H,2H2,1H3,(H,6,7)" ; chebi:inchikey "YIYBQIKDCADOSF-UHFFFAOYSA-N" ; chebi:mass "100.11582" ; chebi:monoisotopicmass "100.05243" ; chebi:smiles "[H]C(CC)=CC(O)=O" ; oboInOwl:hasDbXref "CAS:626-98-2", "LIPID_MAPS_instance:LMFA01030005", "Reaxys:1720310" ; oboInOwl:hasExactSynonym "pent-2-enoic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-pentenoic acid", "C5:1, n-3", "Pent-2-ensaeure", "Propylidenessigsaeure", "alpha-Butylen-alpha-carbonsaeure", "alpha-pentenoic acid", "alpha.beta-Pentensaeure", "beta-Aethyl-acrylsaeure", "beta-Aethylacrylsaeure", "beta-ethyl acrylic acid" ; oboInOwl:id "CHEBI:35939" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pent-2-enoic acid" ; rdfs:subClassOf obo:CHEBI_25897, obo:CHEBI_79020 . obo:CHEBI_35942 obo:IAO_0000115 "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "neurotransmitter agents" ; oboInOwl:id "CHEBI:35942" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "neurotransmitter agent" ; rdfs:subClassOf obo:CHEBI_23888, obo:CHEBI_52210 . obo:CHEBI_35987 obo:IAO_0000115 "Any amino acid carrying two amino groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:35987" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diamino acid" ; rdfs:subClassOf obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_59561 ] . obo:CHEBI_36043 obo:IAO_0000115 "A drug used to treat or prevent microbial infections." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimicrobial drugs" ; oboInOwl:id "CHEBI:36043" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimicrobial drug" ; rdfs:subClassOf obo:CHEBI_33281, obo:CHEBI_35441 . obo:CHEBI_36093 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic chloride salt", "inorganic chloride salts", "inorganic chlorides" ; oboInOwl:id "CHEBI:36093" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic chloride" ; rdfs:subClassOf obo:CHEBI_23114, obo:CHEBI_24839 . obo:CHEBI_36309 oboInOwl:hasExactSynonym "macrocyclic tetrapyrroles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic tetrapyrroles", "macrocyclic tetrapyrrole" ; oboInOwl:id "CHEBI:36309" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic tetrapyrrole" ; rdfs:subClassOf obo:CHEBI_26932, obo:CHEBI_47882 . obo:CHEBI_36315 obo:IAO_0000115 "Any glycerophospholipid having the polar alcohol inositol esterified to the phosphate group at the sn-3 position of the glycerol backbone." ; oboInOwl:hasAlternativeId "CHEBI:26040", "CHEBI:35770" ; oboInOwl:hasDbXref "PMID:14706866" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "GPI", "glycerophosphoinositols" ; oboInOwl:id "CHEBI:36315" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glycerophosphoinositol" ; rdfs:subClassOf obo:CHEBI_37739, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_24848 ] . obo:CHEBI_36338 obo:IAO_0000115 "Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "leptons" ; oboInOwl:id "CHEBI:36338" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "lepton" ; rdfs:subClassOf obo:CHEBI_33233, obo:CHEBI_36340 . obo:CHEBI_36339 obo:IAO_0000115 "Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "baryons" ; oboInOwl:id "CHEBI:36339" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "baryon" ; rdfs:subClassOf obo:CHEBI_36340, obo:CHEBI_36344 . obo:CHEBI_36340 obo:IAO_0000115 "Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi." ; oboInOwl:hasExactSynonym "fermion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fermions" ; oboInOwl:id "CHEBI:36340" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fermion" ; rdfs:subClassOf obo:CHEBI_36342 . obo:CHEBI_36342 obo:IAO_0000115 "A particle smaller than an atom." ; oboInOwl:hasDbXref "Wikipedia:Subatomic_particle" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "subatomic particles" ; oboInOwl:id "CHEBI:36342" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "subatomic particle" . obo:CHEBI_36343 obo:IAO_0000115 "A subatomic particle known to have substructure (i.e. consisting of smaller particles)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "composite particles" ; oboInOwl:id "CHEBI:36343" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "composite particle" ; rdfs:subClassOf obo:CHEBI_36342 . obo:CHEBI_36344 obo:IAO_0000115 "Hadron is a subatomic particle which experiences the strong force." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hadrons" ; oboInOwl:id "CHEBI:36344" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hadron" ; rdfs:subClassOf obo:CHEBI_36343 . obo:CHEBI_36347 obo:IAO_0000115 "A nucleus or any of its constituents in any of their energy states." ; oboInOwl:hasExactSynonym "nuclear particle" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36347" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nuclear particle" ; rdfs:subClassOf obo:CHEBI_36342 . obo:CHEBI_36357 obo:IAO_0000115 "Any molecular entity consisting of more than one atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic entities" ; oboInOwl:id "CHEBI:36357" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polyatomic entity" ; rdfs:subClassOf obo:CHEBI_23367, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_24433 ] . obo:CHEBI_36358 obo:IAO_0000115 "An ion consisting of more than one atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic ions" ; oboInOwl:id "CHEBI:36358" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polyatomic ion" ; rdfs:subClassOf obo:CHEBI_24870, obo:CHEBI_36357 . obo:CHEBI_36359 oboInOwl:hasExactSynonym "phosphorus oxoacid derivative" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36359" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphorus oxoacid derivative" ; rdfs:subClassOf obo:CHEBI_33241, obo:CHEBI_36360, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33457 ] . obo:CHEBI_36360 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36360" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "phosphorus oxoacids and derivatives" ; rdfs:subClassOf obo:CHEBI_26082 . obo:CHEBI_3638 obo:IAO_0000115 "An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis." ; chebi:charge "0" ; chebi:formula "C18H26ClN3" ; chebi:inchi "InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)" ; chebi:inchikey "WHTVZRBIWZFKQO-UHFFFAOYSA-N" ; chebi:mass "319.87200" ; chebi:monoisotopicmass "319.18153" ; chebi:smiles "CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12" ; oboInOwl:hasDbXref "Beilstein:482809", "CAS:54-05-7", "DrugBank:DB00608", "Drug_Central:607", "Gmelin:781126", "HMDB:HMDB0014746", "KEGG:C07625", "KEGG:D02366", "LINCS:LSM-1901", "PDBeChem:CLQ", "PMID:11198399", "PMID:17594118", "PMID:18052874", "PMID:19426658", "PMID:23288916", "PMID:23580861", "PMID:23635029", "PMID:23644906", "PMID:23706562", "PMID:23852712", "PMID:23891850", "PMID:25285162", "Patent:DE683692", "Patent:US2233970", "Reaxys:482809", "Wikipedia:Chloroquine" ; oboInOwl:hasExactSynonym "Chloroquine", "N(4)-(7-chloroquinolin-4-yl)-N(1),N(1)-diethylpentane-1,4-diamine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Aralen", "Artrichin", "Bemaphate", "Capquin", "Chlorochin", "N(4)-(7-chloro-4-quinolinyl)-N(1),N(1)-diethyl-1,4-pentanediamine", "Nivaquine B", "Resoquine", "Reumachlor", "Sanoquin", "chloroquine", "chloroquinum", "cloroquina" ; oboInOwl:id "CHEBI:3638" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chloroquine" ; rdfs:subClassOf obo:CHEBI_36683, obo:CHEBI_36709, obo:CHEBI_50995, obo:CHEBI_50996, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149553 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35842 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50177 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_88230 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_149484 ] . obo:CHEBI_36380 chebi:charge "0" ; chebi:formula "C25H32N2" ; chebi:inchi "InChI=1S/C25H32N2/c1-2-18-17-27-14-12-20-8-4-6-10-23(20)25(27)16-21(18)15-24-22-9-5-3-7-19(22)11-13-26-24/h3-10,18,21,24-26H,2,11-17H2,1H3/t18-,21-,24+,25-/m0/s1" ; chebi:inchikey "KSQYVPHTTWSOHG-CKBKHPSWSA-N" ; chebi:mass "360.53506" ; chebi:monoisotopicmass "360.25655" ; chebi:smiles "[H][C@]1(C[C@@]2([H])NCCc3ccccc23)C[C@]2([H])N(CCc3ccccc23)C[C@@H]1CC" ; oboInOwl:hasExactSynonym "emetan" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36380" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "emetan" ; rdfs:subClassOf obo:CHEBI_24921, obo:CHEBI_24922, obo:CHEBI_38515 . obo:CHEBI_36416 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mancude organic heterotricyclic parents", "mancude-ring organic heterotricyclic parents" ; oboInOwl:id "CHEBI:36416" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mancude organic heterotricyclic parent" ; rdfs:subClassOf obo:CHEBI_26979, obo:CHEBI_35571 . obo:CHEBI_36586 obo:IAO_0000115 "Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives." ; oboInOwl:hasExactSynonym "carbonyl compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36586" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbonyl compound" ; rdfs:subClassOf obo:CHEBI_36587, obo:CHEBI_36963, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_23019 ] . obo:CHEBI_36587 obo:IAO_0000115 "Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element." ; oboInOwl:hasExactSynonym "oxo compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic oxo compounds" ; oboInOwl:id "CHEBI:36587" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic oxo compound" ; rdfs:subClassOf obo:CHEBI_72695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_46629 ] . obo:CHEBI_36683 obo:IAO_0000115 "An organochlorine compound is a compound containing at least one carbon-chlorine bond." ; chebi:charge "0" ; chebi:formula "ClR" ; chebi:mass "35.453" ; chebi:monoisotopicmass "34.96885" ; chebi:smiles "*Cl" ; oboInOwl:hasDbXref "MetaCyc:Chlorides", "Wikipedia:Organochloride" ; oboInOwl:hasExactSynonym "organochlorine compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an organochlorine molecule", "chloroorganic compounds", "chlororganische Verbindungen", "organochloride", "organochloride compound", "organochloride compounds", "organochlorides", "organochlorine compounds" ; oboInOwl:id "CHEBI:36683" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organochlorine compound" ; rdfs:subClassOf obo:CHEBI_17792, obo:CHEBI_23117 . obo:CHEBI_36688 oboInOwl:hasExactSynonym "heterotricyclic compound", "heterotricyclic compounds" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterotricyclic compounds" ; oboInOwl:id "CHEBI:36688" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heterotricyclic compound" ; rdfs:subClassOf obo:CHEBI_33671 . obo:CHEBI_36709 obo:IAO_0000115 "Any member of the class of quinolines in which the quinoline skeleton is substituted by one or more amino or substituted-amino groups." ; oboInOwl:hasExactSynonym "aminoquinoline" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aminoquinolines" ; oboInOwl:id "CHEBI:36709" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aminoquinoline" ; rdfs:subClassOf obo:CHEBI_26513, obo:CHEBI_33860 . obo:CHEBI_36810 obo:IAO_0000115 "A fluorohydrocarbon that is fluoroform in which the hydrogen is substituted by a phenyl group." ; chebi:charge "0" ; chebi:formula "C7H5F3" ; chebi:inchi "InChI=1S/C7H5F3/c8-7(9,10)6-4-2-1-3-5-6/h1-5H" ; chebi:inchikey "GETTZEONDQJALK-UHFFFAOYSA-N" ; chebi:mass "146.10980" ; chebi:monoisotopicmass "146.03433" ; chebi:smiles "FC(F)(F)c1ccccc1" ; oboInOwl:hasDbXref "Beilstein:1906908", "CAS:98-08-8", "Gmelin:3670", "PMID:11671431", "PMID:20958547", "PMID:24267073", "PMID:24669762", "Reaxys:1906908" ; oboInOwl:hasExactSynonym "(trifluoromethyl)benzene" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C6H5CF3", "CF3Ph", "PhCF3", "alpha,alpha,alpha-trifluorotoluene", "benzotrifluoride", "omega-trifluorotoluene", "phenylfluoroform", "trifluoromethylbenzene" ; oboInOwl:id "CHEBI:36810" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(trifluoromethyl)benzene" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_46695, obo:CHEBI_83565, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_46787 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_41550 ] . obo:CHEBI_36820 obo:IAO_0000115 "Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved." ; oboInOwl:hasExactSynonym "ring assemblies", "ring assembly" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36820" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ring assembly" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_36828 oboInOwl:hasExactSynonym "pseudohalide ions" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pseudohalide anions", "pseudohalides", "pseudohalogen anion", "pseudohalogen ion" ; oboInOwl:id "CHEBI:36828" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pseudohalide anion" ; rdfs:subClassOf obo:CHEBI_36829 . obo:CHEBI_36829 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polyatomic monoanions" ; oboInOwl:id "CHEBI:36829" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polyatomic monoanion" ; rdfs:subClassOf obo:CHEBI_33273, obo:CHEBI_36830 . obo:CHEBI_36830 chebi:charge "-1" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoanions" ; oboInOwl:id "CHEBI:36830" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoanion" ; rdfs:subClassOf obo:CHEBI_22563 . obo:CHEBI_36841 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "11-hydroxy steroids" ; oboInOwl:id "CHEBI:36841" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "11-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:CHEBI_36848 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-hydroxy steroids" ; oboInOwl:id "CHEBI:36848" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "5-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:CHEBI_36860 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "14-hydroxy steroids" ; oboInOwl:id "CHEBI:36860" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "14-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_35350 . obo:CHEBI_36862 obo:IAO_0000115 "A 14-hydroxy steroid in which the hydroxy group has a beta-configuration." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "14beta-hydroxy steroids" ; oboInOwl:id "CHEBI:36862" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "14beta-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_36860 . obo:CHEBI_36892 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36892" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental fluorine" ; rdfs:subClassOf obo:CHEBI_33434 . obo:CHEBI_36893 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36893" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental iodine" ; rdfs:subClassOf obo:CHEBI_33434 . obo:CHEBI_36894 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:36894" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental bromine" ; rdfs:subClassOf obo:CHEBI_33434 . obo:CHEBI_36895 chebi:charge "0" ; chebi:formula "F" ; chebi:mass "18.998" ; chebi:monoisotopicmass "18.99840" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic fluorine" ; oboInOwl:id "CHEBI:36895" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic fluorine" ; rdfs:subClassOf obo:CHEBI_36892 . obo:CHEBI_36896 chebi:charge "0" ; chebi:formula "Br" ; chebi:mass "79.904" ; chebi:monoisotopicmass "78.91834" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic bromine" ; oboInOwl:id "CHEBI:36896" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic bromine" ; rdfs:subClassOf obo:CHEBI_36894 . obo:CHEBI_36897 chebi:charge "0" ; chebi:formula "I" ; chebi:mass "126.904" ; chebi:monoisotopicmass "126.90447" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "atomic iodine" ; oboInOwl:id "CHEBI:36897" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoatomic iodine" ; rdfs:subClassOf obo:CHEBI_36893 . obo:CHEBI_36902 oboInOwl:hasExactSynonym "chalcogen hydride" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcogen hydrides" ; oboInOwl:id "CHEBI:36902" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chalcogen hydride" ; rdfs:subClassOf obo:CHEBI_33242, obo:CHEBI_33304 . obo:CHEBI_36914 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic ions" ; oboInOwl:id "CHEBI:36914" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic ion" ; rdfs:subClassOf obo:CHEBI_24835, obo:CHEBI_24870 . obo:CHEBI_36915 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic cations" ; oboInOwl:id "CHEBI:36915" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic cation" ; rdfs:subClassOf obo:CHEBI_36914, obo:CHEBI_36916 . obo:CHEBI_36916 obo:IAO_0000115 "A monoatomic or polyatomic species having one or more elementary charges of the proton." ; oboInOwl:hasAlternativeId "CHEBI:23058", "CHEBI:3473" ; oboInOwl:hasDbXref "KEGG:C01373" ; oboInOwl:hasExactSynonym "Cation", "cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Kation", "Kationen", "cationes", "cations" ; oboInOwl:id "CHEBI:36916" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cation" ; rdfs:subClassOf obo:CHEBI_24870 . obo:CHEBI_36919 oboInOwl:hasExactSynonym "antimony molecular entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimony compounds", "antimony molecular entities" ; oboInOwl:id "CHEBI:36919" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimony molecular entity" ; rdfs:subClassOf obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_30513 ] . obo:CHEBI_36920 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimony oxoacids", "oxoacids of antimony" ; oboInOwl:id "CHEBI:36920" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimony oxoacid" ; rdfs:subClassOf obo:CHEBI_33408, obo:CHEBI_50007 . obo:CHEBI_36921 oboInOwl:hasExactSynonym "antimony oxoanion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimony oxoanions", "oxoanions of antimony" ; oboInOwl:id "CHEBI:36921" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimony oxoanion" ; rdfs:subClassOf obo:CHEBI_24834, obo:CHEBI_33459, obo:CHEBI_50007 . obo:CHEBI_36961 oboInOwl:hasExactSynonym "chalcocarbonic acid", "chalcocarbonic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chalcocarbonic acids" ; oboInOwl:id "CHEBI:36961" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chalcocarbonic acid" ; rdfs:subClassOf obo:CHEBI_36962 . obo:CHEBI_36962 obo:IAO_0000115 "An organochalcogen compound is a compound containing at least one carbon-chalcogen bond." ; oboInOwl:hasExactSynonym "organochalcogen compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organochalcogen compounds" ; oboInOwl:id "CHEBI:36962" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organochalcogen compound" ; rdfs:subClassOf obo:CHEBI_33285, obo:CHEBI_33304 . obo:CHEBI_36963 obo:IAO_0000115 "An organochalcogen compound containing at least one carbon-oxygen bond." ; oboInOwl:hasDbXref "PMID:17586126" ; oboInOwl:hasExactSynonym "organooxygen compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organooxygen compounds" ; oboInOwl:id "CHEBI:36963" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organooxygen compound" ; rdfs:subClassOf obo:CHEBI_25806, obo:CHEBI_36962 . obo:CHEBI_36976 obo:IAO_0000115 "A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid." ; oboInOwl:hasAlternativeId "CHEBI:13215", "CHEBI:13663", "CHEBI:7656" ; oboInOwl:hasDbXref "KEGG:C00215", "Wikipedia:Nucleotide" ; oboInOwl:hasExactSynonym "Nucleotide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleotides" ; oboInOwl:id "CHEBI:36976" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleotide" ; rdfs:subClassOf obo:CHEBI_25608 . obo:CHEBI_36982 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic purine nucleotides" ; oboInOwl:id "CHEBI:36982" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic purine nucleotide" ; rdfs:subClassOf obo:CHEBI_23447, obo:CHEBI_26395 . obo:CHEBI_37015 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleoside 5'-phosphates" ; oboInOwl:id "CHEBI:37015" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribonucleoside 5'-phosphate" ; rdfs:subClassOf obo:CHEBI_16701, obo:CHEBI_26561 . obo:CHEBI_37022 oboInOwl:hasExactSynonym "amino-acid anion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino acid anions", "amino-acid anions" ; oboInOwl:id "CHEBI:37022" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amino-acid anion" ; rdfs:subClassOf obo:CHEBI_29067, obo:CHEBI_35352, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33709 ] . obo:CHEBI_37045 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "purine ribonucleoside 5'-triphosphates" ; oboInOwl:id "CHEBI:37045" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "purine ribonucleoside 5'-triphosphate" ; rdfs:subClassOf obo:CHEBI_26398, obo:CHEBI_26400, obo:CHEBI_37076 . obo:CHEBI_37076 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleoside 5'-triphosphates" ; oboInOwl:id "CHEBI:37076" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribonucleoside 5'-triphosphate" ; rdfs:subClassOf obo:CHEBI_37015 . obo:CHEBI_37096 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenosine 5'-phosphates" ; oboInOwl:id "CHEBI:37096" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adenosine 5'-phosphate" ; rdfs:subClassOf obo:CHEBI_22256 . obo:CHEBI_37141 obo:IAO_0000115 "A compound containing at least one carbon-bromine bond." ; chebi:charge "0" ; chebi:formula "BrR" ; chebi:mass "79.904" ; chebi:monoisotopicmass "78.91834" ; chebi:smiles "*Br" ; oboInOwl:hasDbXref "MetaCyc:Bromide", "Wikipedia:Organobromine_compound" ; oboInOwl:hasExactSynonym "organobromine compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an organobromine molecule", "bromoorganic compound", "organobromide", "organobromide compound", "organobromide compounds", "organobromides", "organobromine compounds" ; oboInOwl:id "CHEBI:37141" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organobromine compound" ; rdfs:subClassOf obo:CHEBI_17792, obo:CHEBI_22928 . obo:CHEBI_37143 obo:IAO_0000115 "An organofluorine compound is a compound containing at least one carbon-fluorine bond." ; chebi:charge "0" ; chebi:formula "FR" ; chebi:mass "18.998" ; chebi:monoisotopicmass "18.99840" ; chebi:smiles "*F" ; oboInOwl:hasDbXref "MetaCyc:Fluorides" ; oboInOwl:hasExactSynonym "organofluorine compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fluoroorganic compound", "fluoroorganic compounds", "fluoroorganics", "fluororganische Verbindungen", "organofluorine compounds" ; oboInOwl:id "CHEBI:37143" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organofluorine compound" ; rdfs:subClassOf obo:CHEBI_17792, obo:CHEBI_24062 . obo:CHEBI_37163 obo:IAO_0000115 "A polysaccharide composed of glucose residues." ; chebi:formula "C12H22O11(C6H10O5)n" ; oboInOwl:hasAlternativeId "CHEBI:24255", "CHEBI:5392" ; oboInOwl:hasDbXref "CAS:9037-91-6", "KEGG:C01379" ; oboInOwl:hasExactSynonym "Glucan", "glucan" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glucans" ; oboInOwl:id "CHEBI:37163" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glucan" ; rdfs:subClassOf obo:CHEBI_37164 . obo:CHEBI_37164 obo:IAO_0000115 "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'." ; oboInOwl:hasExactSynonym "homopolysaccharide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "homoglycan", "homopolysaccharides" ; oboInOwl:id "CHEBI:37164" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "homopolysaccharide" ; rdfs:subClassOf obo:CHEBI_18154 . obo:CHEBI_37175 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic hydrides" ; oboInOwl:id "CHEBI:37175" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic hydride" ; rdfs:subClassOf obo:CHEBI_33692 . obo:CHEBI_37176 oboInOwl:hasExactSynonym "mononuclear parent hydrides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mononuclear hydride", "mononuclear hydrides" ; oboInOwl:id "CHEBI:37176" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mononuclear parent hydride" ; rdfs:subClassOf obo:CHEBI_33692 . obo:CHEBI_37206 obo:IAO_0000115 "A polyol that contains 6 hydroxy groups." ; oboInOwl:hasExactSynonym "hexol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hexols" ; oboInOwl:id "CHEBI:37206" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hexol" ; rdfs:subClassOf obo:CHEBI_26191 . obo:CHEBI_37246 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37246" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental sodium" ; rdfs:subClassOf obo:CHEBI_26712 . obo:CHEBI_37253 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37253" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental zinc" ; rdfs:subClassOf obo:CHEBI_27364 . obo:CHEBI_37404 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37404" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "elemental copper" ; rdfs:subClassOf obo:CHEBI_23377 . obo:CHEBI_37415 obo:IAO_0000115 "A heterodetic cyclic peptide consisting of eight amino acid residues and containing a thioether bridge between a cysteine and a tryptophan residue. It is found in a number of poisonous mushrooms, including Amanita phalloides (the death cap), Galerina marginata, and and Conocybe filaris." ; chebi:charge "0" ; chebi:formula "C39H54N10O14S" ; chebi:inchi "InChI=1S/C39H54N10O14S/c1-4-16(2)31-36(60)42-11-29(55)43-25-15-64(63)38-21(20-6-5-18(51)7-22(20)46-38)9-23(33(57)41-12-30(56)47-31)44-37(61)32(17(3)27(53)14-50)48-35(59)26-8-19(52)13-49(26)39(62)24(10-28(40)54)45-34(25)58/h5-7,16-17,19,23-27,31-32,46,50-53H,4,8-15H2,1-3H3,(H2,40,54)(H,41,57)(H,42,60)(H,43,55)(H,44,61)(H,45,58)(H,47,56)(H,48,59)/t16-,17-,19+,23-,24-,25-,26-,27-,31-,32-,64+/m0/s1" ; chebi:inchikey "CIORWBWIBBPXCG-SXZCQOKQSA-N" ; chebi:mass "918.97106" ; chebi:monoisotopicmass "918.35417" ; chebi:smiles "[H][C@]12Cc3c([nH]c4cc(O)ccc34)[S@](=O)C[C@]([H])(NC(=O)CNC(=O)[C@@]([H])(NC(=O)CNC1=O)[C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N1C[C@H](O)C[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)[C@@H](O)CO)C(=O)N2" ; oboInOwl:hasAlternativeId "CHEBI:10207", "CHEBI:37414" ; oboInOwl:hasDbXref "Beilstein:1071138", "CAS:23109-05-9", "KEGG:C08438", "KNApSAcK:C00001516", "PMID:109306", "PMID:17525082", "PMID:19556115", "PMID:20529816", "PMID:23763309", "PMID:6208374", "PMID:6630208", "PMID:9093889", "Reaxys:1071138", "Wikipedia:Alpha-amanitin" ; oboInOwl:hasExactSynonym "1,8-anhydro-S(1),C(2.5)-cyclo[L-cysteinyl-L-asparaginyl-trans-4-hydroxy-L-prolyl-(R)-4,5-dihydroxy-L-isoleucyl-6-hydroxy-L-tryptophylglycyl-L-isoleucylglycine] (R)-S(1)-oxide", "alpha-Amanitin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-Amanitine", "alpha-Amatoxin" ; oboInOwl:id "CHEBI:37415" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-amanitin" ; rdfs:subClassOf obo:CHEBI_24533, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25442 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37416 ] . obo:CHEBI_37416 obo:IAO_0000115 "An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6)." ; oboInOwl:hasDbXref "Wikipedia:RNA_polymerase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C RNA formation factors inhibitor", "C RNA formation factors inhibitors", "C ribonucleic acid formation factors inhibitor", "C ribonucleic acid formation factors inhibitors", "DNA-dependent RNA nucleotidyltransferase inhibitor", "DNA-dependent RNA nucleotidyltransferase inhibitors", "DNA-dependent RNA polymerase inhibitor", "DNA-dependent RNA polymerase inhibitors", "DNA-dependent ribonucleate nucleotidyltransferase inhibitor", "DNA-dependent ribonucleate nucleotidyltransferase inhibitors", "DNA-directed RNA polymerase inhibitor", "DNA-directed RNA polymerase inhibitors", "DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitor", "DNA-directed nucleoside-triphosphate:RNA nucleotidyltransferase inhibitors", "EC 2.7.7.6 (RNA polymerase) inhibitors", "EC 2.7.7.6 inhibitor", "EC 2.7.7.6 inhibitors", "RNA nucleotidyltransferase (DNA-directed) inhibitor", "RNA nucleotidyltransferase (DNA-directed) inhibitors", "RNA nucleotidyltransferase inhibitor", "RNA nucleotidyltransferase inhibitors", "RNA polymerase (EC 2.7.7.6) inhibitor", "RNA polymerase (EC 2.7.7.6) inhibitors", "RNA polymerase I inhibitor", "RNA polymerase I inhibitors", "RNA polymerase II inhibitor", "RNA polymerase II inhibitors", "RNA polymerase III inhibitor", "RNA polymerase III inhibitors", "RNA polymerase inhibitor", "RNA polymerase inhibitors", "RNA transcriptase inhibitor", "RNA transcriptase inhibitors", "deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitor", "deoxyribonucleic acid-dependent ribonucleic acid polymerase inhibitors", "directed RNA polymerase inhibitor", "nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitor", "nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed) inhibitors", "ribonucleate nucleotidyltransferase inhibitor", "ribonucleate nucleotidyltransferase inhibitors", "ribonucleate polymerase inhibitor", "ribonucleate polymerase inhibitors", "ribonucleic acid nucleotidyltransferase inhibitor", "ribonucleic acid nucleotidyltransferase inhibitors", "ribonucleic acid polymerase inhibitor", "ribonucleic acid polymerase inhibitors", "ribonucleic acid transcriptase inhibitor", "ribonucleic acid transcriptase inhibitors", "ribonucleic polymerase inhibitor", "ribonucleic polymerase inhibitors", "ribonucleic transcriptase inhibitor", "ribonucleic transcriptase inhibitors", "transcriptase inhibitor", "transcriptase inhibitors" ; oboInOwl:id "CHEBI:37416" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.7.7.6 (RNA polymerase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76815 . obo:CHEBI_37526 chebi:charge "0" ; chebi:formula "C20H34" ; chebi:inchi "InChI=1S/C20H34/c1-11-6-14-7-12(2)9-16-18(15(14)8-11)13(3)10-17-19(16)20(17,4)5/h11-19H,6-10H2,1-5H3/t11-,12+,13-,14+,15-,16-,17-,18-,19+/m1/s1" ; chebi:inchikey "CGVXVPQJMYMMIH-HKDZDBKOSA-N" ; chebi:mass "274.485" ; chebi:monoisotopicmass "274.26605" ; chebi:smiles "C1[C@@]2([C@@]([C@]3([C@@](C[C@H](C3)C)(C[C@@H]1C)[H])[H])([C@H](C)C[C@@]4([C@]2(C4(C)C)[H])[H])[H])[H]" ; oboInOwl:hasDbXref "CAS:67707-87-3" ; oboInOwl:hasExactSynonym "(1aS,1bR,3S,4aS,6R,7aR,7bR,8R,9aR)-1,1,3,6,8-pentamethyltetradecahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulene", "tigliane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Tiglian" ; oboInOwl:id "CHEBI:37526" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tigliane" ; rdfs:subClassOf obo:CHEBI_35190, obo:CHEBI_35662 . obo:CHEBI_37527 obo:IAO_0000115 "An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid)." ; oboInOwl:hasAlternativeId "CHEBI:13800", "CHEBI:13801", "CHEBI:22209", "CHEBI:2426" ; oboInOwl:hasDbXref "KEGG:C00174" ; oboInOwl:hasExactSynonym "Acid", "acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Saeure", "Saeuren", "acide", "acido", "acids" ; oboInOwl:id "CHEBI:37527" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acid" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_37532 obo:IAO_0000115 "Esters of phorbol, originally found in croton oil (from Croton tiglium, of the family Euphorbiaceae). A number of phorbol esters possess activity as tumour promoters and activate the mechanisms associated with cell growth. Some of these are used in experiments as activators of protein kinase C." ; oboInOwl:hasDbXref "PMID:17661218", "PMID:19944127", "PMID:27007372" ; oboInOwl:hasExactSynonym "phorbol ester" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37532" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phorbol ester" ; rdfs:subClassOf obo:CHEBI_33308, obo:CHEBI_52557, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_8116 ] . obo:CHEBI_37577 obo:IAO_0000115 "A molecular entity consisting of two or more chemical elements." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chemical compound", "heteroatomic molecular entities" ; oboInOwl:id "CHEBI:37577" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heteroatomic molecular entity" ; rdfs:subClassOf obo:CHEBI_36357 . obo:CHEBI_37578 obo:IAO_0000115 "Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements." ; oboInOwl:hasDbXref "Wikipedia:Halide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halides" ; oboInOwl:id "CHEBI:37578" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halide" ; rdfs:subClassOf obo:CHEBI_24471, obo:CHEBI_37577 . obo:CHEBI_37581 obo:IAO_0000115 "A lactone having a five-membered lactone ring." ; chebi:charge "0" ; chebi:formula "C4H3O2R3" ; chebi:mass "83.066" ; chebi:monoisotopicmass "83.01330" ; chebi:smiles "O1C(C(C(C1=O)*)*)*" ; oboInOwl:hasAlternativeId "CHEBI:13194", "CHEBI:18937", "CHEBI:22971", "CHEBI:541" ; oboInOwl:hasDbXref "PMID:18789684" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,4-Lactone", "1,4-lactones", "a 1,4-lactone", "butyrolactones", "gamma-Laktone", "gamma-lactona", "gamma-lactonas", "gamma-lactones" ; oboInOwl:id "CHEBI:37581" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "gamma-lactone" ; rdfs:subClassOf obo:CHEBI_25000 . obo:CHEBI_37622 obo:IAO_0000115 "An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom." ; chebi:charge "0" ; chebi:formula "CNOR3" ; chebi:mass "42.01680" ; chebi:monoisotopicmass "41.99799" ; chebi:smiles "[*]C(=O)N([*])[*]" ; oboInOwl:hasAlternativeId "CHEBI:35354", "CHEBI:35355" ; oboInOwl:hasExactSynonym "carboxamides" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carboxamides", "primary carboxamide" ; oboInOwl:id "CHEBI:37622" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carboxamide" ; rdfs:subClassOf obo:CHEBI_33256, obo:CHEBI_35352, obo:CHEBI_36963, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_23004 ] . obo:CHEBI_37699 obo:IAO_0000115 "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "protein kinase inhibitors" ; oboInOwl:id "CHEBI:37699" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "protein kinase inhibitor" ; rdfs:subClassOf obo:CHEBI_76668 . obo:CHEBI_37733 obo:IAO_0000115 "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "BChE inhibitor", "BChE inhibitors", "BtChoEase inhibitor", "BtChoEase inhibitors", "EC 3.1.1.8 (cholinesterase) inhibitors", "EC 3.1.1.8 inhibitor", "EC 3.1.1.8 inhibitors", "anticholineesterase inhibitor", "anticholineesterase inhibitors", "anticholinesterase", "anticholinesterases", "benzoylcholinesterase inhibitor", "benzoylcholinesterase inhibitors", "butyrylcholine esterase inhibitor", "butyrylcholine esterase inhibitors", "butyrylcholinesterase inhibitor", "butyrylcholinesterase inhibitors", "choline esterase II (unspecific) inhibitor", "choline esterase II (unspecific) inhibitors", "choline esterase inhibitor", "choline esterase inhibitors", "cholinesterase (EC 3.1.1.8) inhibitor", "cholinesterase (EC 3.1.1.8) inhibitors", "cholinesterase inhibitor", "non-specific cholinesterase inhibitor", "non-specific cholinesterase inhibitors", "propionylcholinesterase inhibitor", "propionylcholinesterase inhibitors", "pseudocholinesterase inhibitor", "pseudocholinesterase inhibitors" ; oboInOwl:id "CHEBI:37733" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.1.1.8 (cholinesterase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76773 . obo:CHEBI_37734 oboInOwl:hasAlternativeId "CHEBI:26019" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:37734" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "phosphoric ester" ; rdfs:subClassOf obo:CHEBI_26079, obo:CHEBI_35701 . obo:CHEBI_37739 obo:IAO_0000115 "Any glycerolipid having a phosphate group ester-linked to a terminal carbon of the glycerol backbone." ; oboInOwl:hasAlternativeId "CHEBI:24362", "CHEBI:5456" ; oboInOwl:hasDbXref "PMID:17393491" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glycerophospholipids", "phosphatide", "phosphatides", "phosphoglyceride", "phosphoglycerides" ; oboInOwl:id "CHEBI:37739" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glycerophospholipid" ; rdfs:subClassOf obo:CHEBI_16247, obo:CHEBI_35741 . obo:CHEBI_37749 oboInOwl:hasExactSynonym "halogen oxide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halogen oxides" ; oboInOwl:id "CHEBI:37749" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halogen oxide" ; rdfs:subClassOf obo:CHEBI_24471, obo:CHEBI_24836 . obo:CHEBI_37750 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chlorine oxides" ; oboInOwl:id "CHEBI:37750" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chlorine oxide" ; rdfs:subClassOf obo:CHEBI_37749 . obo:CHEBI_37838 obo:IAO_0000115 "A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid." ; oboInOwl:hasExactSynonym "carboacyl groups", "carboxylic acyl group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carboxylic acyl groups" ; oboInOwl:id "CHEBI:37838" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carboacyl group" ; rdfs:subClassOf obo:CHEBI_22221, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_33575 ] . obo:CHEBI_37868 obo:IAO_0000115 "A fatty alcohol consisting of a hydroxy function at any position of an unbranched saturated chain of eight carbon atoms." ; chebi:charge "0" ; chebi:formula "C8H18O" ; chebi:mass "130.228" ; chebi:monoisotopicmass "130.13577" ; oboInOwl:hasDbXref "CAS:29063-28-3" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Oktanol", "Oktylalkohol", "hydoxyoctane", "hydoxyoctanes", "n-octanol", "octanols", "octyl alcohol" ; oboInOwl:id "CHEBI:37868" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "octanol" ; rdfs:subClassOf obo:CHEBI_134179, obo:CHEBI_197506, obo:CHEBI_50584, [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_17590 ] . obo:CHEBI_37886 obo:IAO_0000115 "An agent that selectively binds to and activates adrenergic receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adrenergic agonists", "adrenergic receptor agonist", "adrenoceptor agonists", "adrenomimetic", "adrenomimetics" ; oboInOwl:id "CHEBI:37886" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adrenergic agonist" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_37887 obo:IAO_0000115 "An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adrenergic antagonists", "adrenergic blockaders", "adrenergic blocker", "adrenergic blockers", "adrenergic receptor blockaders", "adrenoceptor antagonists" ; oboInOwl:id "CHEBI:37887" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adrenergic antagonist" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_37890 obo:IAO_0000115 "An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-adrenergic antagonists", "alpha-adrenergic blocker", "alpha-adrenergic blockers", "alpha-adrenergic receptor blockaders", "alpha-adrenoceptor antagonists" ; oboInOwl:id "CHEBI:37890" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-adrenergic antagonist" ; rdfs:subClassOf obo:CHEBI_37887, obo:CHEBI_48539 . obo:CHEBI_37948 obo:IAO_0000115 "A spiro compound in which at least one of the cyclic components is an oxygen heterocyle." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxaspiro compounds" ; oboInOwl:id "CHEBI:37948" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxaspiro compound" ; rdfs:subClassOf obo:CHEBI_33599 . obo:CHEBI_37955 obo:IAO_0000115 "H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine." ; oboInOwl:hasDbXref "PMID:22035879" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H1 antihistaminics", "H1 receptor antagonists", "H1 receptor blockaders", "H1-receptor antagonists", "H1-receptor blocker", "H1-receptor blockers", "classical antihistamines", "classical antihistaminics" ; oboInOwl:id "CHEBI:37955" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "H1-receptor antagonist" ; rdfs:subClassOf obo:CHEBI_37956 . obo:CHEBI_37956 obo:IAO_0000115 "Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists." ; oboInOwl:hasDbXref "PMID:22035879", "Wikipedia:Antihistamines" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antihistamine", "antihistamines", "antihistaminico", "antihistaminics", "histamine receptor blocker", "histamine receptor blockers" ; oboInOwl:id "CHEBI:37956" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "histamine antagonist" ; rdfs:subClassOf obo:CHEBI_37957, obo:CHEBI_48706 . obo:CHEBI_37957 obo:IAO_0000115 "Drugs used for their actions on histaminergic systems." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "histamine agents", "histamine drugs", "histaminergic agent", "histaminergic agents", "histaminergic drugs" ; oboInOwl:id "CHEBI:37957" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "histaminergic drug" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_37962 obo:IAO_0000115 "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adrenergic agents", "adrenergic drug", "adrenergic drugs", "adrenergic neuron agents", "adrenergics" ; oboInOwl:id "CHEBI:37962" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adrenergic agent" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_38032 obo:IAO_0000115 "A carbopolyclic compound comprising of three carbocyclic rings." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbotricyclic compounds" ; oboInOwl:id "CHEBI:38032" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbotricyclic compound" ; rdfs:subClassOf obo:CHEBI_35294, obo:CHEBI_51959 . obo:CHEBI_38068 obo:IAO_0000115 "A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimalarials" ; oboInOwl:id "CHEBI:38068" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimalarial" ; rdfs:subClassOf obo:CHEBI_64915 . obo:CHEBI_38070 obo:IAO_0000115 "A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-arrhythmia agent", "antiarrhythmic agent" ; oboInOwl:id "CHEBI:38070" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anti-arrhythmia drug" ; rdfs:subClassOf obo:CHEBI_35554 . obo:CHEBI_38077 obo:IAO_0000115 "A compound composed of two or more pyrrole units." ; oboInOwl:hasDbXref "Beilstein:8538310" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "PPys", "poly(pyrrole)s", "polypyrroles" ; oboInOwl:id "CHEBI:38077" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polypyrrole" ; rdfs:subClassOf obo:CHEBI_38101 . obo:CHEBI_38092 obo:IAO_0000115 "Any member of the class of cardenolides with glycosyl residues attached to position 3." ; oboInOwl:hasAlternativeId "CHEBI:23035", "CHEBI:38080", "CHEBI:38082" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5alpha-cardenolide glycoside", "5beta-cardenolide glycoside" ; oboInOwl:id "CHEBI:38092" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cardenolide glycoside" ; rdfs:subClassOf obo:CHEBI_74634, obo:CHEBI_83970 . obo:CHEBI_38101 obo:IAO_0000115 "Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterocyclic organonitrogen compounds", "organonitrogen heterocyclic compounds" ; oboInOwl:id "CHEBI:38101" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organonitrogen heterocyclic compound" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_35352 . obo:CHEBI_38104 obo:IAO_0000115 "Any organic heterocyclic compound containing at least one ring oxygen atom." ; oboInOwl:hasDbXref "PMID:17134300" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterocyclic organooxygen compounds", "organooxygen heterocyclic compounds", "oxacycles" ; oboInOwl:id "CHEBI:38104" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxacycle" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_36963 . obo:CHEBI_38106 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "heterocyclic organosulfur compounds", "organosulfur heterocyclic compounds" ; oboInOwl:id "CHEBI:38106" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organosulfur heterocyclic compound" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_33261 . obo:CHEBI_38147 obo:IAO_0000115 "A drug that has a strengthening effect on the heart or that can increase cardiac output." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cardiotonic drugs" ; oboInOwl:id "CHEBI:38147" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cardiotonic drug" ; rdfs:subClassOf obo:CHEBI_35554 . obo:CHEBI_38166 oboInOwl:hasAlternativeId "CHEBI:25429", "CHEBI:38075" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic heteropolycyclic compounds" ; oboInOwl:id "CHEBI:38166" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic heteropolycyclic compound" ; rdfs:subClassOf obo:CHEBI_24532, obo:CHEBI_33671 . obo:CHEBI_38179 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monocyclic heteroarenes" ; oboInOwl:id "CHEBI:38179" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monocyclic heteroarene" ; rdfs:subClassOf obo:CHEBI_33833 . obo:CHEBI_38180 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polycyclic heteroarenes" ; oboInOwl:id "CHEBI:38180" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polycyclic heteroarene" ; rdfs:subClassOf obo:CHEBI_33833 . obo:CHEBI_38195 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5beta-hydroxy steroids" ; oboInOwl:id "CHEBI:38195" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "5beta-hydroxy steroid" ; rdfs:subClassOf obo:CHEBI_136889, obo:CHEBI_36848 . obo:CHEBI_38215 obo:IAO_0000115 "One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium channel antagonist", "calcium channel antagonists", "calcium channel blockers" ; oboInOwl:id "CHEBI:38215" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "calcium channel blocker" ; rdfs:subClassOf obo:CHEBI_38808, obo:CHEBI_48706 . obo:CHEBI_38222 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38222" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "hydrocarbyl anion" ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_38260 obo:IAO_0000115 "Any of a class of heterocyclic amines having a saturated five-membered ring." ; oboInOwl:hasAlternativeId "CHEBI:26922", "CHEBI:38191" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38260" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyrrolidines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_38275 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyrrolidinones" ; oboInOwl:id "CHEBI:38275" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyrrolidinone" ; rdfs:subClassOf obo:CHEBI_38260 . obo:CHEBI_38313 obo:IAO_0000115 "Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38313" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diazines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101 . obo:CHEBI_38314 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38314" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyrazines" ; rdfs:subClassOf obo:CHEBI_38313 . obo:CHEBI_38323 obo:IAO_0000115 "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cholinergic agent", "cholinergic drugs", "cholinomimetic" ; oboInOwl:id "CHEBI:38323" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cholinergic drug" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_38324 obo:IAO_0000115 "Any drug that binds to and activates cholinergic receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acetylcholine agonist", "acetylcholine agonists", "acetylcholine receptor agonist", "cholinergic agonists", "cholinomimetic", "cholinomimetics" ; oboInOwl:id "CHEBI:38324" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cholinergic agonist" ; rdfs:subClassOf obo:CHEBI_38323 . obo:CHEBI_38325 obo:IAO_0000115 "Any drug that binds to and activates a muscarinic cholinergic receptor." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "muscarinic acetylcholine receptor agonist", "muscarinic agonists", "muscarinic cholinergic agonist", "muscarinic cholinergic agonists" ; oboInOwl:id "CHEBI:38325" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "muscarinic agonist" ; rdfs:subClassOf obo:CHEBI_38324 . obo:CHEBI_38329 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:38329" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxazolidines" ; rdfs:subClassOf obo:CHEBI_25693, obo:CHEBI_38101, obo:CHEBI_38104 . obo:CHEBI_38337 obo:IAO_0000115 "A pyrimidine carrying one or more oxo substituents." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyrimidones" ; oboInOwl:id "CHEBI:38337" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyrimidone" ; rdfs:subClassOf obo:CHEBI_39447 . obo:CHEBI_38366 obo:IAO_0000115 "A pent-3-enoic acid in trans- configuration." ; chebi:charge "0" ; chebi:formula "C5H8O2" ; chebi:inchi "InChI=1S/C5H8O2/c1-2-3-4-5(6)7/h3-4H,2H2,1H3,(H,6,7)/b4-3+" ; chebi:inchikey "YIYBQIKDCADOSF-ONEGZZNKSA-N" ; chebi:mass "100.11582" ; chebi:monoisotopicmass "100.05243" ; chebi:smiles "CC\\C=C\\C(O)=O" ; oboInOwl:hasDbXref "CAS:13991-37-2", "LIPID_MAPS_instance:LMFA01030005", "Reaxys:1720312" ; oboInOwl:hasExactSynonym "(2E)-pent-2-enoic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(2E)-2-pentenoic acid", "(E)-2-pentenic acid", "(E)-2-pentenoic acid", "(E)-pent-2-en-1-oic acid", "5:1, n-3 trans", "C5:1, n-3 trans", "E-2-Pentencarbonsaeure", "Pent-2t-ensaeure", "trans-2-pentenic acid", "trans-2-pentenoic acid", "trans-Pent-2-ensaeure", "trans-alpha,beta-penteneoic acid" ; oboInOwl:id "CHEBI:38366" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "trans-pent-2-enoic acid" ; rdfs:subClassOf obo:CHEBI_35939 . obo:CHEBI_38461 obo:IAO_0000115 "Derivatives of carbamic acid with insecticidal properties of general formula ROC(=O)NR(1)R(2), where ROH is an alcohol, oxime, or phenol and R(1) is hydrogen or methyl. Like organophosphate insecticides, they are cholinesterase inhibitors, but carbamate insecticides differ in action from the organophosphates in that the inhibitory effect on cholinesterase is generally brief." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbamate insecticides" ; oboInOwl:id "CHEBI:38461" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbamate insecticide" ; rdfs:subClassOf obo:CHEBI_24852, obo:CHEBI_38462 . obo:CHEBI_38462 obo:IAO_0000115 "An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid." ; oboInOwl:hasDbXref "Wikipedia:Acetylcholinesterase_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "AChEI", "AcCholE inhibitor", "AcCholE inhibitors", "EC 3.1.1.7 (acetylcholinesterase) inhibitors", "EC 3.1.1.7 inhibitor", "EC 3.1.1.7 inhibitors", "acetyl.beta-methylcholinesterase inhibitor", "acetyl.beta-methylcholinesterase inhibitors", "acetylcholine acetylhydrolase inhibitor", "acetylcholine acetylhydrolase inhibitors", "acetylcholine esterase inhibitor", "acetylcholine hydrolase inhibitor", "acetylcholine hydrolase inhibitors", "acetylcholinesterase (EC 3.1.1.7) inhibitor", "acetylcholinesterase (EC 3.1.1.7) inhibitors", "acetylcholinesterase inhibitor", "acetylcholinesterase inhibitors", "acetylthiocholinesterase inhibitor", "acetylthiocholinesterase inhibitors", "choline esterase I inhibitor", "choline esterase I inhibitors", "cholinesterase inhibitor", "cholinesterase inhibitors", "true cholinesterase inhibitor", "true cholinesterase inhibitors" ; oboInOwl:id "CHEBI:38462" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.1.1.7 (acetylcholinesterase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76773 . obo:CHEBI_38515 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isoquinoline alkaloid fundamental parents" ; oboInOwl:id "CHEBI:38515" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isoquinoline alkaloid fundamental parent" ; rdfs:subClassOf obo:CHEBI_35506 . obo:CHEBI_38534 chebi:charge "0" ; chebi:formula "C3H7NOS" ; chebi:inchi "InChI=1S/C3H7NOS/c1-3(4-5)6-2/h5H,1-2H3" ; chebi:inchikey "TYEVWCPZVQACAE-UHFFFAOYSA-N" ; chebi:mass "105.15982" ; chebi:monoisotopicmass "105.02484" ; chebi:smiles "CSC(C)=NO" ; oboInOwl:hasDbXref "Beilstein:1901214", "CAS:13749-94-5" ; oboInOwl:hasExactSynonym "methyl N-hydroxyethanimidothioate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-(Methylthio)acetaldehyde oxime", "1-(Methylthio)acetaldoxime", "Methomyl oxime", "Methyl N-hydroxyacetimidothioate", "Methyl N-hydroxyethanimidothioate", "Methyl thioacetohydroxamate" ; oboInOwl:id "CHEBI:38534" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "1-(methylsulfanyl)acetaldoxime" ; rdfs:subClassOf obo:CHEBI_86315, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_51280 ] . obo:CHEBI_38627 obo:IAO_0000115 "The parent structure of the diazines." ; chebi:charge "0" ; chebi:formula "C4H4N2" ; chebi:mass "80.088" ; chebi:monoisotopicmass "80.03745" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Diazin" ; oboInOwl:id "CHEBI:38627" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diazine" ; rdfs:subClassOf obo:CHEBI_35555, obo:CHEBI_38179, obo:CHEBI_38313, obo:CHEBI_50893 . obo:CHEBI_38631 oboInOwl:hasAlternativeId "CHEBI:22503", "CHEBI:24792" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aminoalkylindoles" ; oboInOwl:id "CHEBI:38631" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aminoalkylindole" ; rdfs:subClassOf obo:CHEBI_24828 . obo:CHEBI_38632 obo:IAO_0000115 "Any agent that affects the transport of molecular entities across a biological membrane." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "membrane transport modulators" ; oboInOwl:id "CHEBI:38632" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "membrane transport modulator" ; rdfs:subClassOf obo:CHEBI_52208 . obo:CHEBI_38700 oboInOwl:hasExactSynonym "organic sodium salt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic sodium salts" ; oboInOwl:id "CHEBI:38700" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic sodium salt" ; rdfs:subClassOf obo:CHEBI_24868, obo:CHEBI_26714 . obo:CHEBI_38702 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic sodium salts" ; oboInOwl:id "CHEBI:38702" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic sodium salt" ; rdfs:subClassOf obo:CHEBI_24839, obo:CHEBI_26714 . obo:CHEBI_38808 obo:IAO_0000115 "A membrane transport modulator that is able to regulate intracellular calcium levels." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium channel modulators" ; oboInOwl:id "CHEBI:38808" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "calcium channel modulator" ; rdfs:subClassOf obo:CHEBI_38632 . obo:CHEBI_38809 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RyR modulator", "ryanodine receptor modulators", "ryanodine-sensitive calcium channel modulator", "ryanodine-sensitive calcium-release channel modulator" ; oboInOwl:id "CHEBI:38809" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ryanodine receptor modulator" ; rdfs:subClassOf obo:CHEBI_38808 . obo:CHEBI_38824 obo:IAO_0000115 "Compounds consisting wholly of fluorine and carbon." ; oboInOwl:hasExactSynonym "fluorocarbon", "fluorocarbons" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fluorocarbons" ; oboInOwl:id "CHEBI:38824" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluorocarbon" ; rdfs:subClassOf obo:CHEBI_37143 . obo:CHEBI_38825 chebi:charge "0" ; chebi:formula "CF4" ; chebi:inchi "InChI=1S/CF4/c2-1(3,4)5" ; chebi:inchikey "TXEYQDLBPFQVAA-UHFFFAOYSA-N" ; chebi:mass "88.00431" ; chebi:monoisotopicmass "87.99361" ; chebi:smiles "FC(F)(F)F" ; oboInOwl:hasDbXref "Beilstein:1697288", "CAS:75-73-0", "Gmelin:2016" ; oboInOwl:hasExactSynonym "tetrafluoromethane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CF4", "Freon 14", "Halon 14", "Tetrafluorkohlenstoff", "Tetrafluormethan", "carbon tetrafluoride", "perfluoromethane", "tetrafluoridocarbon", "tetrafluorocarbon" ; oboInOwl:id "CHEBI:38825" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tetrafluoromethane" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_38824, obo:CHEBI_39281, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_38867 obo:IAO_0000115 "Substance which produces loss of feeling or sensation." ; oboInOwl:hasExactSynonym "anaesthetic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Anaesthetika", "Anaesthetikum", "anaesthetics", "anesthetic agent", "anesthetic drug", "anesthetics" ; oboInOwl:id "CHEBI:38867" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anaesthetic" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_38869 obo:IAO_0000115 "Substance that produces loss of consciousness." ; oboInOwl:hasExactSynonym "general anaesthetic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Allgemeinanaesthetika", "Allgemeinanaesthetikum", "general anaesthetics", "general anesthetics" ; oboInOwl:id "CHEBI:38869" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "general anaesthetic" ; rdfs:subClassOf obo:CHEBI_38867 . obo:CHEBI_38870 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Inhalationsanaesthetika", "Inhalationsanaesthetikum", "Inhalationsnarkotika", "Inhalationsnarkotikum", "anesthetic gases", "inhalation anesthetics" ; oboInOwl:id "CHEBI:38870" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inhalation anaesthetic" ; rdfs:subClassOf obo:CHEBI_38869 . obo:CHEBI_38924 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dibenzothiepines" ; oboInOwl:id "CHEBI:38924" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dibenzothiepine" ; rdfs:subClassOf obo:CHEBI_26979, obo:CHEBI_38106 . obo:CHEBI_38958 obo:IAO_0000115 "An alkaloid containing an indole skeleton." ; oboInOwl:hasAlternativeId "CHEBI:24795", "CHEBI:5901" ; oboInOwl:hasDbXref "KEGG:C06073", "Wikipedia:Indole_alkaloid" ; oboInOwl:hasExactSynonym "Indole alkaloid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "indole alkaloids" ; oboInOwl:id "CHEBI:38958" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "indole alkaloid" ; rdfs:subClassOf obo:CHEBI_22315, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_73398 ] . obo:CHEBI_39123 chebi:formula "Ca" ; chebi:mass "40.078" ; chebi:monoisotopicmass "39.96259" ; oboInOwl:hasExactSynonym "calcium cation" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium cations" ; oboInOwl:id "CHEBI:39123" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "calcium cation" ; rdfs:subClassOf obo:CHEBI_33513, obo:CHEBI_39124 . obo:CHEBI_39124 chebi:charge "0" ; chebi:formula "Ca" ; chebi:mass "40.078" ; chebi:monoisotopicmass "39.96259" ; oboInOwl:hasExactSynonym "calcium ion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "calcium ions" ; oboInOwl:id "CHEBI:39124" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "calcium ion" ; rdfs:subClassOf obo:CHEBI_25213, obo:CHEBI_35155 . obo:CHEBI_39141 obo:IAO_0000115 "A molecular entity capable of donating a hydron to an acceptor (Bronsted base)." ; oboInOwl:hasExactSynonym "Bronsted acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bronsted-Saeure", "acide de Bronsted", "donneur d'hydron", "hydron donor" ; oboInOwl:id "CHEBI:39141" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "Bronsted acid" ; rdfs:subClassOf obo:CHEBI_17891, obo:CHEBI_37527 . obo:CHEBI_39142 obo:IAO_0000115 "A molecular entity capable of accepting a hydron from a donor (Bronsted acid)." ; oboInOwl:hasExactSynonym "Bronsted base" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bronsted-Base", "accepteur d'hydron", "base de Bronsted", "hydron acceptor" ; oboInOwl:id "CHEBI:39142" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "Bronsted base" ; rdfs:subClassOf obo:CHEBI_15339, obo:CHEBI_22695 . obo:CHEBI_39144 obo:IAO_0000115 "A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct." ; oboInOwl:hasExactSynonym "Lewis base" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Lewis-Base", "base de Lewis", "donneur d'une paire d'electrons", "electron donor" ; oboInOwl:id "CHEBI:39144" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "Lewis base" ; rdfs:subClassOf obo:CHEBI_17891, obo:CHEBI_22695 . obo:CHEBI_39162 obo:IAO_0000115 "A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has R-configuration." ; chebi:charge "0" ; chebi:formula "C10H14N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m1/s1" ; chebi:inchikey "SNICXCGAKADSCV-SNVBAGLBSA-N" ; chebi:mass "162.23160" ; chebi:monoisotopicmass "162.11570" ; chebi:smiles "CN1CCC[C@@H]1c1cccnc1" ; oboInOwl:hasDbXref "Beilstein:4666243", "Beilstein:82110", "CAS:25162-00-9", "KEGG:C16386" ; oboInOwl:hasExactSynonym "3-[(2R)-1-methylpyrrolidin-2-yl]pyridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-nicotine", "(R)-3-(1-methyl-2-pyrrolidinyl)pyridine", "d-nicotine", "pseudonicotine" ; oboInOwl:id "CHEBI:39162" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(R)-nicotine" ; rdfs:subClassOf obo:CHEBI_138000, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_79008 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_17688 ] . obo:CHEBI_39208 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39208" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "antibiotic insecticide" ; rdfs:subClassOf obo:CHEBI_24852, obo:CHEBI_39215 . obo:CHEBI_39209 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39209" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "macrolide insecticide" ; rdfs:subClassOf obo:CHEBI_39221, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39208 ] . obo:CHEBI_39213 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39213" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "avermectin insecticide" ; rdfs:subClassOf obo:CHEBI_39209, obo:CHEBI_39220 . obo:CHEBI_39214 obo:IAO_0000115 "Mixture of 80% avermectin B1a and 20% avermectin B1b." ; oboInOwl:hasDbXref "CAS:71751-41-2" ; oboInOwl:hasExactSynonym "Abamectin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Agri-Mek", "Avid", "MK 936", "Zephyr", "avermectin B1" ; oboInOwl:id "CHEBI:39214" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "abamectin" ; rdfs:subClassOf obo:CHEBI_39213, obo:CHEBI_39219, obo:CHEBI_60004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29534 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_29537 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39217 ] . obo:CHEBI_39215 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39215" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "antibiotic pesticide" ; rdfs:subClassOf obo:CHEBI_25944, obo:CHEBI_33281 . obo:CHEBI_39216 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39216" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "antibiotic acaricide" ; rdfs:subClassOf obo:CHEBI_22153, obo:CHEBI_39215 . obo:CHEBI_39217 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39217" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "antibiotic nematicide" ; rdfs:subClassOf obo:CHEBI_25491, obo:CHEBI_39215 . obo:CHEBI_39218 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39218" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "macrolide acaricide" ; rdfs:subClassOf obo:CHEBI_39221, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39216 ] . obo:CHEBI_39219 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39219" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "avermectin acaricide" ; rdfs:subClassOf obo:CHEBI_39218, obo:CHEBI_39220 . obo:CHEBI_39220 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39220" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "avermectin pesticide" ; rdfs:subClassOf obo:CHEBI_39221 . obo:CHEBI_39221 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39221" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "macrolide pesticide" ; rdfs:subClassOf obo:CHEBI_25105 . obo:CHEBI_39279 obo:IAO_0000115 "A haloalkane that is methane in which one (or more) of the hydrogens have been replaced by a halogen atom/halogen atoms." ; oboInOwl:hasExactSynonym "halomethane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "halomethanes" ; oboInOwl:id "CHEBI:39279" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halomethane" ; rdfs:subClassOf obo:CHEBI_24469, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_16183 ] . obo:CHEBI_39281 obo:IAO_0000115 "A halomethane that is methane in which one or more hydrogens has been replaced by fluorine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39281" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluoromethanes" ; rdfs:subClassOf obo:CHEBI_24067, obo:CHEBI_39279 . obo:CHEBI_39418 obo:IAO_0000115 "Any saturated fatty acid lacking a side-chain." ; oboInOwl:hasDbXref "PMID:15644336" ; oboInOwl:hasExactSynonym "straight-chain saturated fatty acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "straight-chain saturated fatty acids" ; oboInOwl:id "CHEBI:39418" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "straight-chain saturated fatty acid" ; rdfs:subClassOf obo:CHEBI_26607, obo:CHEBI_59202, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_58954 ] . obo:CHEBI_39447 obo:IAO_0000115 "Any compound having a pyrimidine as part of its structure." ; oboInOwl:hasAlternativeId "CHEBI:13681", "CHEBI:26448" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:39447" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyrimidines" ; rdfs:subClassOf obo:CHEBI_38313 . obo:CHEBI_39745 obo:IAO_0000115 "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated." ; chebi:charge "-1" ; chebi:formula "H2O4P" ; chebi:inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1" ; chebi:inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-M" ; chebi:mass "96.98724" ; chebi:monoisotopicmass "96.96962" ; chebi:smiles "[H]OP([O-])(=O)O[H]" ; oboInOwl:hasAlternativeId "CHEBI:29137", "CHEBI:39739" ; oboInOwl:hasDbXref "DrugBank:DB02831", "Gmelin:1999", "PDBeChem:2HP" ; oboInOwl:hasExactSynonym "dihydrogen(tetraoxidophosphate)(1-)", "dihydrogenphosphate", "dihydrogentetraoxophosphate(1-)", "dihydrogentetraoxophosphate(V)", "dihydroxidodioxidophosphate(1-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "DIHYDROGENPHOSPHATE ION", "H2PO4(-)", "[PO2(OH)2](-)" ; oboInOwl:id "CHEBI:39745" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dihydrogenphosphate" ; rdfs:subClassOf obo:CHEBI_35780, obo:CHEBI_79389, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_43474 ] . obo:CHEBI_39832 obo:IAO_0000115 "An ether that is the methyl ether derivative of ethanol." ; chebi:charge "0" ; chebi:formula "C3H8O" ; chebi:inchi "InChI=1S/C3H8O/c1-3-4-2/h3H2,1-2H3" ; chebi:inchikey "XOBKSJJDNFUZPF-UHFFFAOYSA-N" ; chebi:mass "60.09500" ; chebi:monoisotopicmass "60.05751" ; chebi:smiles "CCOC" ; oboInOwl:hasDbXref "Beilstein:1730785", "CAS:540-67-0", "Gmelin:163978", "PDBeChem:2ME", "PMID:12662033", "Patent:KR20080019002", "Reaxys:1730785", "Wikipedia:Methoxyethane" ; oboInOwl:hasExactSynonym "METHOXYETHANE", "methoxyethane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-methoxyethane", "Aethylmethylaether", "C2H5OCH3", "Methoxyethan", "Methylaethylaether", "methyl ethyl ether" ; oboInOwl:id "CHEBI:39832" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methoxyethane" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25698, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39144 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16236 ] . obo:CHEBI_3992 oboInOwl:hasDbXref "KEGG:C02019" ; oboInOwl:hasExactSynonym "Cyclic ketone", "cyclic ketones" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:3992" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic ketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_4046 obo:IAO_0000115 "The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia." ; chebi:charge "0" ; chebi:formula "C21H21N" ; chebi:inchi "InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3" ; chebi:inchikey "JJCFRYNCJDLXIK-UHFFFAOYSA-N" ; chebi:mass "287.39810" ; chebi:monoisotopicmass "287.16740" ; chebi:smiles "CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12" ; oboInOwl:hasAlternativeId "CHEBI:111005", "CHEBI:605605" ; oboInOwl:hasDbXref "Beilstein:1348386", "CAS:129-03-3", "DrugBank:DB00434", "Drug_Central:765", "KEGG:C06935", "KEGG:D07765", "LINCS:LSM-5419", "PMID:10843226", "Patent:US3014911", "Wikipedia:Cyproheptadine" ; oboInOwl:hasExactSynonym "4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine", "4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine", "CYPROHEPTADINE", "Cyproheptadine", "cyproheptadine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine", "1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine", "4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine", "4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine", "4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine", "5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene", "ciproheptadina", "cyproheptadine", "cyproheptadinum" ; oboInOwl:id "CHEBI:4046" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyproheptadine" ; rdfs:subClassOf obo:CHEBI_26151, obo:CHEBI_32876, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37955 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48279 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50857 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_55324 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59683 ] . obo:CHEBI_41550 chebi:charge "0" ; chebi:formula "CHF3" ; chebi:inchi "InChI=1S/CHF3/c2-1(3)4/h1H" ; chebi:inchikey "XPDWGBQVDMORPB-UHFFFAOYSA-N" ; chebi:mass "70.01385" ; chebi:monoisotopicmass "70.00303" ; chebi:smiles "[H]C(F)(F)F" ; oboInOwl:hasAlternativeId "CHEBI:24073", "CHEBI:41543" ; oboInOwl:hasDbXref "Beilstein:1731035", "CAS:75-46-7", "Gmelin:1543", "PDBeChem:CFT", "UM-BBD_compID:c0802" ; oboInOwl:hasExactSynonym "fluoroform" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CHF3", "Freon 23", "Freon F-23", "TRIFLUOROMETHANE", "carbon trifluoride", "methyl trifluoride" ; oboInOwl:id "CHEBI:41550" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluoroform" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_39281, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78433 ] . obo:CHEBI_41609 chebi:charge "-2" ; chebi:formula "CO3" ; chebi:inchi "InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2" ; chebi:inchikey "BVKZGUZCCUSVTD-UHFFFAOYSA-L" ; chebi:mass "60.00890" ; chebi:monoisotopicmass "59.98584" ; chebi:smiles "[O-]C([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:29201", "CHEBI:41605" ; oboInOwl:hasDbXref "Beilstein:3600898", "CAS:3812-32-6", "Gmelin:1559", "PDBeChem:CO3" ; oboInOwl:hasExactSynonym "carbonate", "trioxidocarbonate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CARBONATE ION", "CO3(2-)", "Karbonat", "[CO3](2-)" ; oboInOwl:id "CHEBI:41609" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbonate" ; rdfs:subClassOf obo:CHEBI_35604, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17544 ] . obo:CHEBI_42485 chebi:charge "0" ; chebi:formula "CHO" ; chebi:mass "29.01804" ; chebi:monoisotopicmass "29.00274" ; chebi:smiles "[H]C(*)=O" ; oboInOwl:hasAlternativeId "CHEBI:24089", "CHEBI:42480" ; oboInOwl:hasDbXref "PDBeChem:FOR" ; oboInOwl:hasExactSynonym "FORMYL GROUP", "aldehyde group", "carbaldehyde", "formyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-CH(O)", "-CHO", "Fo", "H-CO-", "methanoyl" ; oboInOwl:id "CHEBI:42485" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "formyl group" ; rdfs:subClassOf obo:CHEBI_27207, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_30751 ] . obo:CHEBI_4290 chebi:charge "0" ; chebi:formula "C12H19N2.I" ; chebi:inchi "InChI=1S/C12H19N2.HI/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12;/h3-7H,8-11H2,1-2H3;1H/q+1;/p-1" ; chebi:inchikey "XFZJGFIKQCCLGK-UHFFFAOYSA-M" ; chebi:mass "318.19721" ; chebi:monoisotopicmass "318.05929" ; chebi:smiles "[I-].C[N+]1(C)CCN(CC1)c1ccccc1" ; oboInOwl:hasDbXref "Beilstein:3746109", "CAS:54-77-3", "KEGG:C07488" ; oboInOwl:hasExactSynonym "1,1-Dimethyl-4-phenylpiperazinium Iodide", "1,1-dimethyl-4-phenylpiperazinium iodide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1-Dimethyl-4-phenylpiperazine iodide", "DMPP", "DMPP iodide", "Dimethylphenylpiperazinium iodide", "N,N-Dimethyl-N'-phenylpiperazinium iodide" ; oboInOwl:id "CHEBI:4290" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "1,1-dimethyl-4-phenylpiperazinium iodide" ; rdfs:subClassOf obo:CHEBI_35273, obo:CHEBI_46848, obo:CHEBI_46849, obo:CHEBI_50356, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_47958 ] . obo:CHEBI_43176 chebi:charge "0" ; chebi:formula "HO" ; chebi:mass "17.00734" ; chebi:monoisotopicmass "17.00274" ; chebi:smiles "*O[H]" ; oboInOwl:hasAlternativeId "CHEBI:24706", "CHEBI:43171" ; oboInOwl:hasDbXref "PDBeChem:OH" ; oboInOwl:hasExactSynonym "HYDROXY GROUP", "hydroxy", "hydroxy group" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-OH", "hydroxyl", "hydroxyl group" ; oboInOwl:id "CHEBI:43176" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydroxy group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:CHEBI_43254 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:43254" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "(4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one" ; rdfs:subClassOf obo:CHEBI_38337, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_17568 ] . obo:CHEBI_43451 obo:IAO_0000115 "A diatomic molecule containing covalently bonded hydrogen and iodine atoms." ; chebi:charge "0" ; chebi:formula "HI" ; chebi:inchi "InChI=1S/HI/h1H" ; chebi:inchikey "XMBWDFGMSWQBCA-UHFFFAOYSA-N" ; chebi:mass "127.91241" ; chebi:monoisotopicmass "127.91230" ; chebi:smiles "I[H]" ; oboInOwl:hasAlternativeId "CHEBI:5591" ; oboInOwl:hasDbXref "CAS:10034-85-2", "Gmelin:814", "KEGG:C05590" ; oboInOwl:hasExactSynonym "Hydrogen iodide", "hydrogen iodide", "iodane", "iodidohydrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HI", "Hydrogeniodid", "Hydroiodic acid", "Iodwasserstoff", "Jodwasserstoff", "Wasserstoffiodid", "[HI]", "hydriodic acid", "hydroiodic acid", "iodure d'hydrogene" ; oboInOwl:id "CHEBI:43451" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogen iodide" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_18140, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16382 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_50317 ] . obo:CHEBI_43474 obo:IAO_0000115 "A phosphate ion that is the conjugate base of dihydrogenphosphate." ; chebi:charge "-2" ; chebi:formula "HO4P" ; chebi:inchi "InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-2" ; chebi:inchikey "NBIIXXVUZAFLBC-UHFFFAOYSA-L" ; chebi:mass "95.97930" ; chebi:monoisotopicmass "95.96234" ; chebi:smiles "OP([O-])([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:29139", "CHEBI:43470" ; oboInOwl:hasDbXref "Gmelin:1998", "MolBase:1628", "PDBeChem:PI", "PDBeChem:PO4" ; oboInOwl:hasExactSynonym "hydrogen(tetraoxidophosphate)(2-)", "hydrogenphosphate", "hydrogentetraoxophosphate(2-)", "hydrogentetraoxophosphate(V)", "hydroxidotrioxidophosphate(2-)" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HPO4(2-)", "HYDROGENPHOSPHATE ION", "INORGANIC PHOSPHATE GROUP", "[P(OH)O3](2-)", "[PO3(OH)](2-)", "hydrogen phosphate", "phosphate" ; oboInOwl:id "CHEBI:43474" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogenphosphate" ; rdfs:subClassOf obo:CHEBI_35780, obo:CHEBI_79388, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_18367 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_39745 ] . obo:CHEBI_43799 obo:IAO_0000115 "A primary aliphatic amine that is butane substituted by an amino group at position 1." ; chebi:charge "0" ; chebi:formula "C4H11N" ; chebi:inchi "InChI=1S/C4H11N/c1-2-3-4-5/h2-5H2,1H3" ; chebi:inchikey "HQABUPZFAYXKJW-UHFFFAOYSA-N" ; chebi:mass "73.13680" ; chebi:monoisotopicmass "73.08915" ; chebi:smiles "CCCCN" ; oboInOwl:hasDbXref "Beilstein:605269", "CAS:109-73-9", "DrugBank:DB03659", "Gmelin:1784", "MetaCyc:BUTYLAMINE", "PDBeChem:LYT", "PMID:16387436", "PMID:23470444", "PMID:23734590", "Reaxys:605269", "Wikipedia:N-Butylamine" ; oboInOwl:hasExactSynonym "butan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-Aminobutan", "1-aminobutane", "1-butanamine", "1-butylamine", "BUTYLAMINE", "butanamine", "butylamine", "mono-n-butylamine", "monobutylamine", "n-Butylamin", "n-C4H9NH2", "n-butylamine" ; oboInOwl:id "CHEBI:43799" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "butan-1-amine" ; rdfs:subClassOf obo:CHEBI_17062 . obo:CHEBI_44423 obo:IAO_0000115 "A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease." ; chebi:charge "0" ; chebi:formula "CH4N2O2" ; chebi:inchi "InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)" ; chebi:inchikey "VSNHCAURESNICA-UHFFFAOYSA-N" ; chebi:mass "76.05474" ; chebi:monoisotopicmass "76.02728" ; chebi:smiles "NC(=O)NO" ; oboInOwl:hasAlternativeId "CHEBI:44420", "CHEBI:5816" ; oboInOwl:hasDbXref "Beilstein:1741548", "CAS:127-07-1", "DrugBank:DB01005", "Drug_Central:1399", "Gmelin:130423", "HMDB:HMDB0015140", "KEGG:C07044", "KEGG:D00341", "MetaCyc:HYDROXY-UREA", "PDBeChem:NHY", "PMID:11285159", "PMID:11298103", "PMID:11364534", "PMID:11365149", "PMID:11391710", "PMID:12107454", "PMID:14988684", "PMID:15772364", "PMID:15994344", "PMID:16356682", "PMID:22983419", "PMID:23318979", "PMID:23643402", "PMID:23696560", "PMID:9271088", "Patent:US2705727", "Reaxys:1741548", "Wikipedia:Hydroxyurea" ; oboInOwl:hasExactSynonym "Hydroxyurea", "N-hydroxyurea", "hydroxyurea" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Hydroxycarbamid", "Hydroxycarbamide", "Hydroxyharnstoff", "N-HYDROXYUREA", "N-carbamoylhydroxylamine", "carbamohydroxamic acid", "carbamohydroximic acid", "carbamoyl oxime", "carbamyl hydroxamate", "hidroxicarbamida", "hydrea", "hydroxycarbamide", "hydroxycarbamidum", "oxyurea" ; oboInOwl:id "CHEBI:44423" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydroxyurea" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_47857, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35221 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35610 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48578 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50846 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50902 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50905 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_59517 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_64911 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_74213 ] . obo:CHEBI_45379 obo:IAO_0000115 "An amino acid consisting of carbamic acid having an N-methyl substituent." ; chebi:charge "0" ; chebi:formula "C2H5NO2" ; chebi:inchi "InChI=1S/C2H5NO2/c1-3-2(4)5/h3H,1H3,(H,4,5)" ; chebi:inchikey "UFEJKYYYVXYMMS-UHFFFAOYSA-N" ; chebi:mass "75.067" ; chebi:monoisotopicmass "75.03203" ; chebi:smiles "CNC(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:38464", "CHEBI:45374" ; oboInOwl:hasDbXref "Beilstein:1738994", "CAS:6414-57-9", "PDBeChem:RGI", "PMID:13663920", "PMID:18491873", "PMID:21311787", "PMID:21687849", "PMID:22382393", "PMID:28083911", "PMID:33146910", "Reaxys:1738994" ; oboInOwl:hasExactSynonym "methylcarbamic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Methylcarbamidsaeure", "N-methylcarbamic acid" ; oboInOwl:id "CHEBI:45379" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methylcarbamic acid" ; rdfs:subClassOf obo:CHEBI_33709, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76976 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_28616 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_193111 ] . obo:CHEBI_46345 obo:IAO_0000115 "A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth." ; chebi:charge "0" ; chebi:formula "C4H3FN2O2" ; chebi:inchi "InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)" ; chebi:inchikey "GHASVSINZRGABV-UHFFFAOYSA-N" ; chebi:mass "130.07730" ; chebi:monoisotopicmass "130.01786" ; chebi:smiles "Fc1c[nH]c(=O)[nH]c1=O" ; oboInOwl:hasAlternativeId "CHEBI:2054", "CHEBI:46343" ; oboInOwl:hasDbXref "Beilstein:127172", "CAS:51-21-8", "DrugBank:DB00544", "Drug_Central:26", "HMDB:HMDB0014684", "KEGG:C07649", "KEGG:D00584", "LINCS:LSM-4261", "PDBeChem:URF", "PMID:11356943", "PMID:12520460", "PMID:14769231", "PMID:19023200", "Reaxys:127172", "Wikipedia:Fluorouracil" ; oboInOwl:hasExactSynonym "5-Fluorouracil", "5-fluoropyrimidine-2,4(1H,3H)-dione", "5-fluorouracil" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-FU", "5-Fluoracil", "5-Fluoropyrimidine-2,4-dione", "Fluorouracil", "fluorouracil", "fluorouracilo", "fluorouracilum" ; oboInOwl:id "CHEBI:46345" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "5-fluorouracil" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_37143, obo:CHEBI_67142, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_132992 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35221 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35610 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35705 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17568 ] . obo:CHEBI_46629 chebi:charge "0" ; chebi:formula "O" ; chebi:mass "15.99940" ; chebi:monoisotopicmass "15.99491" ; chebi:smiles "O=*" ; oboInOwl:hasAlternativeId "CHEBI:29353", "CHEBI:44607" ; oboInOwl:hasDbXref "PDBeChem:O" ; oboInOwl:hasExactSynonym "OXO GROUP", "oxo" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "=O" ; oboInOwl:id "CHEBI:46629" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxo group" ; rdfs:subClassOf obo:CHEBI_33246 . obo:CHEBI_46640 obo:IAO_0000115 "A compound that contains two ketone functionalities." ; oboInOwl:hasDbXref "Wikipedia:Diketone" ; oboInOwl:hasExactSynonym "diketones" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:46640" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_46695 obo:IAO_0000115 "A compound derived from a hydrocarbon by replacing one or more hydrogen atoms with fluorine atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "FKW", "Fluorkohlenwasserstoffe", "HFC", "fluorohydrocarbons" ; oboInOwl:id "CHEBI:46695" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluorohydrocarbon" ; rdfs:subClassOf obo:CHEBI_24472, obo:CHEBI_37143 . obo:CHEBI_46775 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-alkylpyrrolidines" ; oboInOwl:id "CHEBI:46775" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "N-alkylpyrrolidine" ; rdfs:subClassOf obo:CHEBI_38260, obo:CHEBI_50996 . obo:CHEBI_46787 obo:IAO_0000115 "A liquid that can dissolve other substances (solutes) without any change in their chemical composition." ; oboInOwl:hasDbXref "Wikipedia:Solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Loesungsmittel", "solvant", "solvents" ; oboInOwl:id "CHEBI:46787" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "solvent" ; rdfs:subClassOf obo:CHEBI_33232, obo:CHEBI_51086 . obo:CHEBI_46800 chebi:charge "0" ; chebi:formula "C2H4OS" ; chebi:inchi "InChI=1S/C2H4OS/c1-2(3)4/h1H3,(H,3,4)" ; chebi:inchikey "DUYAAUVXQSMXQP-UHFFFAOYSA-N" ; chebi:mass "76.11856" ; chebi:monoisotopicmass "75.99829" ; chebi:smiles "CC(O)=S" ; oboInOwl:hasDbXref "Beilstein:1733298", "Gmelin:1216872" ; oboInOwl:hasExactSynonym "ethanethioic O-acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:46800" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ethanethioic O-acid" ; rdfs:subClassOf obo:CHEBI_26952, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16555 ] . obo:CHEBI_46845 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-alkylpiperazines" ; oboInOwl:id "CHEBI:46845" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "N-alkylpiperazine" ; rdfs:subClassOf obo:CHEBI_26144, obo:CHEBI_50996 . obo:CHEBI_46848 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-arylpiperazines" ; oboInOwl:id "CHEBI:46848" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "N-arylpiperazine" ; rdfs:subClassOf obo:CHEBI_26144, obo:CHEBI_33860, obo:CHEBI_50996 . obo:CHEBI_46849 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "piperazinium salts" ; oboInOwl:id "CHEBI:46849" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "piperazinium salt" ; rdfs:subClassOf obo:CHEBI_46850 . obo:CHEBI_46850 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organoammonium salts" ; oboInOwl:id "CHEBI:46850" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organoammonium salt" ; rdfs:subClassOf obo:CHEBI_35276 . obo:CHEBI_46883 chebi:charge "0" ; chebi:formula "CHO2" ; chebi:mass "45.01744" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "*C(=O)O" ; oboInOwl:hasAlternativeId "CHEBI:23025", "CHEBI:41420" ; oboInOwl:hasDbXref "PDBeChem:FMT" ; oboInOwl:hasExactSynonym "CARBOXY GROUP", "carboxy" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-C(O)OH", "-CO2H", "-COOH", "carboxyl group" ; oboInOwl:id "CHEBI:46883" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carboxy group" ; rdfs:subClassOf obo:CHEBI_33249 . obo:CHEBI_46997 obo:IAO_0000115 "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in L-glyceraldehyde." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:mass "150.130" ; chebi:monoisotopicmass "150.05282" ; oboInOwl:hasExactSynonym "L-ribo-pentose", "L-ribose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-Rib" ; oboInOwl:id "CHEBI:46997" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-ribose" ; rdfs:subClassOf obo:CHEBI_33942, [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_16988 ] . obo:CHEBI_46998 obo:IAO_0000115 "A cyclic ribose having a 5-membered tetrahydrofuran ring; the predominant (C3'-endo) form of the two cyclic structures (the other is the \"C2'-endo\" form, having a 6-membered ring) adopted by ribose in aqueous solution." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:mass "150.12990" ; chebi:monoisotopicmass "150.05282" ; oboInOwl:hasExactSynonym "ribofuranose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "rel-(3R,4S,5R)-5-(hydroxymethyl)tetrahydrofuran-2,3,4-triol" ; oboInOwl:id "CHEBI:46998" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribofuranose" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33942, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_84735 ] . obo:CHEBI_47013 obo:IAO_0000115 "A ribofuranose having D-configuration." ; chebi:charge "0" ; chebi:formula "C5H10O5" ; chebi:inchi "InChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5?/m1/s1" ; chebi:inchikey "HMFHBZSHGGEWLO-SOOFDHNKSA-N" ; chebi:mass "150.12990" ; chebi:monoisotopicmass "150.05282" ; chebi:smiles "OC[C@H]1OC(O)[C@H](O)[C@@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:4233", "CHEBI:46999" ; oboInOwl:hasDbXref "Beilstein:1904878", "CAS:50-69-1", "CAS:613-83-2", "GlyGen:G31080DL", "GlyTouCan:G31080DL", "Gmelin:364108", "KEGG:C00121", "PMID:9506998", "Patent:US2152662", "Reaxys:1904878" ; oboInOwl:hasExactSynonym "D-ribofuranose" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(3R,4S,5R)-5-(hydroxymethyl)tetrahydrofuran-2,3,4-triol", "D-Ribose", "D-ribose", "WURCS=2.0/1,1,0/[a222h-1x_1-4]/1/", "ribose" ; oboInOwl:id "CHEBI:47013" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-ribofuranose" ; rdfs:subClassOf obo:CHEBI_16988, obo:CHEBI_46998 . obo:CHEBI_47017 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tetrahydrofuranols" ; oboInOwl:id "CHEBI:47017" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tetrahydrofuranol" ; rdfs:subClassOf obo:CHEBI_26912 . obo:CHEBI_47019 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dihydroxytetrahydrofurans" ; oboInOwl:id "CHEBI:47019" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dihydroxytetrahydrofuran" ; rdfs:subClassOf obo:CHEBI_47017 . obo:CHEBI_47266 obo:IAO_0000115 "A diatomic molecule containing covalently bonded hydrogen and bromine atoms." ; chebi:charge "0" ; chebi:formula "BrH", "HBr" ; chebi:inchi "InChI=1S/BrH/h1H" ; chebi:inchikey "CPELXLSAUQHCOX-UHFFFAOYSA-N" ; chebi:mass "80.91194" ; chebi:monoisotopicmass "79.92616" ; chebi:smiles "Br[H]" ; oboInOwl:hasAlternativeId "CHEBI:29134", "CHEBI:31673" ; oboInOwl:hasDbXref "CAS:10035-10-6", "Gmelin:620", "KEGG:C13645" ; oboInOwl:hasExactSynonym "bromane", "bromidohydrogen", "hydrogen bromide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Bromwasserstoff", "HBr", "Hydrobromic acid", "Hydrogenbromid", "[HBr]", "bromure d'hydrogene" ; oboInOwl:id "CHEBI:47266" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogen bromide" ; rdfs:subClassOf obo:CHEBI_138675, obo:CHEBI_18140, obo:CHEBI_37176, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_15858 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_50316 ] . obo:CHEBI_472805 obo:IAO_0000115 "A steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been isolated naturally from Strophanthus gratus." ; chebi:charge "0" ; chebi:formula "C29H44O12" ; chebi:inchi "InChI=1S/C29H44O12/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-/m0/s1" ; chebi:inchikey "LPMXVESGRSUGHW-HBYQJFLCSA-N" ; chebi:mass "584.65250" ; chebi:monoisotopicmass "584.28328" ; chebi:smiles "[H][C@@]12CC[C@]3(O)C[C@H](C[C@@H](O)[C@]3(CO)[C@@]1([H])[C@H](O)C[C@]1(C)[C@H](CC[C@]21O)C1=CC(=O)OC1)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O" ; oboInOwl:hasAlternativeId "CHEBI:44461", "CHEBI:7805" ; oboInOwl:hasDbXref "Beilstein:101712", "CAS:630-60-4", "DrugBank:DB01092", "Drug_Central:2004", "FooDB:FDB005482", "HMDB:HMDB0015224", "KEGG:C01443", "KEGG:D00112", "KNApSAcK:C00003633", "LINCS:LSM-2781", "LIPID_MAPS_instance:LMST01120022", "PDBeChem:OBN", "PMID:10438974", "PMID:1316269", "PMID:16529963", "PMID:20372980", "PMID:31075189", "PMID:31170971", "PMID:31548455", "PMID:31986323", "PMID:32326025", "PMID:32368275", "PMID:32488807", "PMID:32569558", "PMID:9872395", "Reaxys:101712", "Wikipedia:Ouabain" ; oboInOwl:hasExactSynonym "3-(6-deoxy-alpha-L-mannopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide", "Ouabain" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3-(alpha-L-rhamnopyranosyloxy)-1beta,5beta,11alpha,14,19-pentahydroxy-5beta-card-20(22)-enolide", "G-Strophanthin", "Ouabagenin L-Rhamnoside", "Ouabagenin-L-rhamnosid", "Ouabain anhydrous", "Ouabaine", "Oubain", "Strodival" ; oboInOwl:id "CHEBI:472805" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ouabain" ; rdfs:subClassOf obo:CHEBI_19129, obo:CHEBI_26764, obo:CHEBI_27848, obo:CHEBI_36862, obo:CHEBI_38092, obo:CHEBI_38195, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38070 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38147 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_49200 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50184 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63510 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77023 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77024 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_145798 ] . obo:CHEBI_47499 obo:IAO_0000115 "A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom." ; chebi:charge "0" ; chebi:formula "C19H24N2" ; chebi:inchi "InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3" ; chebi:inchikey "BCGWQEUPMDMJNV-UHFFFAOYSA-N" ; chebi:mass "280.40734" ; chebi:monoisotopicmass "280.19395" ; chebi:smiles "CN(C)CCCN1c2ccccc2CCc2ccccc12" ; oboInOwl:hasAlternativeId "CHEBI:47498", "CHEBI:5881" ; oboInOwl:hasDbXref "Beilstein:256892", "CAS:50-49-7", "DrugBank:DB00458", "Drug_Central:1427", "Gmelin:1572523", "HMDB:HMDB0001848", "KEGG:C07049", "KEGG:D08070", "LINCS:LSM-2852", "PDBeChem:IXX", "PMID:20825390", "Patent:US2554736", "Reaxys:256892", "Wikipedia:Imipramine" ; oboInOwl:hasExactSynonym "3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine", "Imipramine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine", "3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE", "5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine", "Antideprin", "Imipramin", "Irmin", "Melipramine", "N-(gamma-dimethylaminopropyl)iminodibenzyl", "imipramine", "imipraminum", "imizine" ; oboInOwl:id "CHEBI:47499" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "imipramine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_47804, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35640 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76779 ], [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_47802 ] . obo:CHEBI_47622 obo:IAO_0000115 "Any carboxylic ester where the carboxylic acid component is acetic acid." ; chebi:charge "0" ; chebi:formula "C2H3O2R" ; chebi:mass "59.04400" ; chebi:monoisotopicmass "59.01330" ; chebi:smiles "CC(=O)O[*]" ; oboInOwl:hasAlternativeId "CHEBI:13244", "CHEBI:13799", "CHEBI:22189", "CHEBI:2406" ; oboInOwl:hasDbXref "KEGG:C01883", "Wikipedia:Acetate#Esters" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Acetic ester", "Acetyl ester", "acetate", "acetate esters", "acetates", "acetyl esters", "an acetyl ester" ; oboInOwl:id "CHEBI:47622" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acetate ester" ; rdfs:subClassOf obo:CHEBI_33308, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_15366 ] . obo:CHEBI_47704 oboInOwl:hasExactSynonym "ammonium salt" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ammoniumsalz", "Ammoniumsalze", "ammonium salts" ; oboInOwl:id "CHEBI:47704" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ammonium salt" ; rdfs:subClassOf obo:CHEBI_35276, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_28938 ] . obo:CHEBI_47802 obo:IAO_0000115 "A mancude organic heterotricyclic parent that consists of a seven-membered nitrogen hetrocycle fused with two benzene rings." ; chebi:charge "0" ; chebi:formula "C14H11N" ; chebi:inchi "InChI=1S/C14H11N/c1-3-7-13-11(5-1)9-10-12-6-2-4-8-14(12)15-13/h1-10,15H" ; chebi:inchikey "LCGTWRLJTMHIQZ-UHFFFAOYSA-N" ; chebi:mass "193.249" ; chebi:monoisotopicmass "193.08915" ; chebi:smiles "N1C2=C(C=CC=C2)C=CC2=C1C=CC=C2" ; oboInOwl:hasDbXref "Beilstein:1343358", "CAS:256-96-2", "Chemspider:8857", "PDBeChem:ONB", "PMID:11767950", "PMID:12052500", "PMID:12061877", "PMID:15837018", "PMID:16203183", "PMID:17236778", "PMID:18779941", "PMID:19486265", "PMID:19774656", "PMID:20922935", "PMID:21087114", "PMID:21441615", "PMID:22322005", "PMID:22751668", "PMID:2322636", "PMID:24358274", "PMID:27175105", "PMID:27389944", "PMID:27807790", "PMID:30660838", "PMID:30754023", "PMID:30823329", "PMID:31718245", "PMID:33381027", "PMID:33842007", "PMID:3680120", "PMID:4146691", "PMID:5982986", "PMID:7587936", "PMID:8385460", "PMID:870507", "Reaxys:1343358", "Wikipedia:Dibenzazepine" ; oboInOwl:hasExactSynonym "5H-dibenzo[b,f]azepine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,2'-iminostilbene", "2,3,6,7-dibenzazepine", "5H-Dibenz[b,f]azepin", "5H-dibenz[b,f]azepine", "5H-dibenzazepine", "dibenz(b,f)azepine", "dibenzazepine", "iminostilbene", "o,o'-iminostilbene" ; oboInOwl:id "CHEBI:47802" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "5H-dibenzo[b,f]azepine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_36416, obo:CHEBI_47804, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_83399 ] . obo:CHEBI_47804 oboInOwl:hasExactSynonym "dibenzoazepine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dibenzazepine", "dibenzoazepines" ; oboInOwl:id "CHEBI:47804" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dibenzoazepine" ; rdfs:subClassOf obo:CHEBI_26979, obo:CHEBI_38101 . obo:CHEBI_4781 obo:IAO_0000115 "A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties." ; chebi:charge "0" ; chebi:formula "C29H40N2O4" ; chebi:inchi "InChI=1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1" ; chebi:inchikey "AUVVAXYIELKVAI-CKBKHPSWSA-N" ; chebi:mass "480.63898" ; chebi:monoisotopicmass "480.29881" ; chebi:smiles "[H][C@]1(C[C@@]2([H])NCCc3cc(OC)c(OC)cc23)C[C@]2([H])N(CCc3cc(OC)c(OC)cc23)C[C@@H]1CC" ; oboInOwl:hasDbXref "Beilstein:100834", "Beilstein:6253162", "CAS:483-18-1", "DrugBank:DB13393", "Drug_Central:1001", "KEGG:C09421", "KNApSAcK:C00001849", "LINCS:LSM-2041", "MetaCyc:CPD-14817", "PMID:14119536", "PMID:16109351", "PMID:17094176", "PMID:19227966", "PMID:29872540", "PMID:31436297", "PMID:31533472", "PMID:31734270", "PMID:31775307", "PMID:31964796", "PMID:32245264", "PMID:32251767", "Reaxys:100834", "Wikipedia:Emetine" ; oboInOwl:hasExactSynonym "6',7',10,11-tetramethoxyemetan", "Emetine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Emetan", "Emetin", "cephaeline methyl ether", "cephaline-O-methyl ether", "methyl cephaeline" ; oboInOwl:id "CHEBI:4781" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "emetine" ; rdfs:subClassOf obo:CHEBI_24921, obo:CHEBI_61692, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149552 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_149553 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_171664 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35610 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38068 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48001 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77035 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_88230 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_3533 ], [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_36380 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_149548 ] . obo:CHEBI_47857 oboInOwl:hasAlternativeId "CHEBI:27220", "CHEBI:36947" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "urea derivatives" ; oboInOwl:id "CHEBI:47857" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ureas" ; rdfs:subClassOf obo:CHEBI_33256, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16199 ] . obo:CHEBI_47867 obo:IAO_0000115 "Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Indikator" ; oboInOwl:id "CHEBI:47867" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "indicator" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_47882 oboInOwl:hasExactSynonym "macrocyclic polypyrroles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic polypyrroles", "polypyrrole macrocycles" ; oboInOwl:id "CHEBI:47882" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic polypyrrole" ; rdfs:subClassOf obo:CHEBI_38077 . obo:CHEBI_47901 obo:IAO_0000115 "Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an alkyl group." ; oboInOwl:hasAlternativeId "CHEBI:13809", "CHEBI:33553" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkanesulfonic acids", "alkylsulfonic acids" ; oboInOwl:id "CHEBI:47901" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkanesulfonic acid" ; rdfs:subClassOf obo:CHEBI_33551, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_22323 ] . obo:CHEBI_4792 obo:IAO_0000115 "An ether in which the oxygen atom is connected to 2-chloro-1,1,2-trifluoroethyl and difluoromethyl groups." ; chebi:charge "0" ; chebi:formula "C3H2ClF5O" ; chebi:inchi "InChI=1S/C3H2ClF5O/c4-1(5)3(8,9)10-2(6)7/h1-2H" ; chebi:inchikey "JPGQOUSTVILISH-UHFFFAOYSA-N" ; chebi:mass "184.49210" ; chebi:monoisotopicmass "183.97143" ; chebi:smiles "FC(F)OC(F)(F)C(F)Cl" ; oboInOwl:hasDbXref "Beilstein:1903921", "CAS:13838-16-9", "DrugBank:DB00228", "Drug_Central:1009", "HMDB:HMDB0014373", "KEGG:C07516", "KEGG:D00543", "PMID:23934553", "PMID:25386744", "PMID:7457058", "Patent:AU2014277860", "Patent:US5783199", "Reaxys:1903921", "Wikipedia:Enflurane" ; oboInOwl:hasExactSynonym "2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane", "Enflurane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-chloro-1,1,2-trifluoroethyl difluoromethyl ether", "Alyrane", "Efrane", "Ethrane", "Methylflurether" ; oboInOwl:id "CHEBI:4792" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "enflurane" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25698, obo:CHEBI_36683, obo:CHEBI_37143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38867 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_39832 ] . obo:CHEBI_47923 obo:IAO_0000115 "Any oligopeptide that consists of three amino-acid residues connected by peptide linkages." ; chebi:charge "0" ; chebi:formula "C6H8N3O4R3" ; chebi:mass "186.146" ; chebi:monoisotopicmass "186.05148" ; chebi:smiles "C(=O)(NC(C(NC(C(=O)O)*)=O)*)C(N)*" ; oboInOwl:hasAlternativeId "CHEBI:27138", "CHEBI:9742" ; oboInOwl:hasDbXref "KEGG:C00316", "Wikipedia:Tripeptide" ; oboInOwl:hasExactSynonym "Tripeptide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tripeptides" ; oboInOwl:id "CHEBI:47923" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tripeptide" ; rdfs:subClassOf obo:CHEBI_25676, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_155837 ] . obo:CHEBI_47958 obo:IAO_0000115 "An agonist that selectively binds to and activates a nicotinic acetylcholine receptor." ; oboInOwl:hasAlternativeId "CHEBI:82738" ; oboInOwl:hasDbXref "Wikipedia:Nicotinic_acetylcholine_receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "muscarinic agonists", "nicotinic acetylcholine receptor agonists", "nicotinic agonist", "nicotinic agonists" ; oboInOwl:id "CHEBI:47958" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nicotinic acetylcholine receptor agonist" ; rdfs:subClassOf obo:CHEBI_38324 . obo:CHEBI_48001 obo:IAO_0000115 "A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "protein synthesis antagonist", "protein synthesis antagonists", "protein synthesis inhibitors" ; oboInOwl:id "CHEBI:48001" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "protein synthesis inhibitor" ; rdfs:subClassOf obo:CHEBI_76932 . obo:CHEBI_48154 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Schwefeloxide", "oxides of sulfur", "sulfur oxides" ; oboInOwl:id "CHEBI:48154" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur oxide" ; rdfs:subClassOf obo:CHEBI_24836, obo:CHEBI_26835 . obo:CHEBI_48218 obo:IAO_0000115 "A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body)." ; oboInOwl:hasDbXref "Wikipedia:Antiseptic" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antiseptic", "antiseptic agent", "antiseptic agents", "antiseptics", "local antiinfective agents", "local microbicides", "topical antiinfective agents", "topical microbicides" ; oboInOwl:id "CHEBI:48218" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antiseptic drug" ; rdfs:subClassOf obo:CHEBI_35441 . obo:CHEBI_48219 obo:IAO_0000115 "An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Desinfektionsmittel", "desinfectant", "disinfectants", "disinfecting agent" ; oboInOwl:id "CHEBI:48219" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "disinfectant" ; rdfs:subClassOf obo:CHEBI_33281 . obo:CHEBI_48278 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "serotonergic agents", "serotonergic drugs", "serotonin drugs" ; oboInOwl:id "CHEBI:48278" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "serotonergic drug" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_48279 obo:IAO_0000115 "Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-HT antagonists", "5-hydroxytryptamine antagonists", "antiserotonergic agents", "serotonin antagonists", "serotonin blockaders" ; oboInOwl:id "CHEBI:48279" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "serotonergic antagonist" ; rdfs:subClassOf obo:CHEBI_48278 . obo:CHEBI_48354 obo:IAO_0000115 "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds." ; oboInOwl:hasExactSynonym "polar solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "polar solvents" ; oboInOwl:id "CHEBI:48354" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polar solvent" ; rdfs:subClassOf obo:CHEBI_46787 . obo:CHEBI_48355 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48355" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "non-polar solvent" ; rdfs:subClassOf obo:CHEBI_46787 . obo:CHEBI_48356 obo:IAO_0000115 "A polar solvent that is capable of acting as a hydron (proton) donor." ; oboInOwl:hasExactSynonym "protogenic solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48356" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "protic solvent" ; rdfs:subClassOf obo:CHEBI_39141, obo:CHEBI_48354 . obo:CHEBI_48357 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48357" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "aprotic solvent" ; rdfs:subClassOf obo:CHEBI_46787 . obo:CHEBI_48358 obo:IAO_0000115 "A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds." ; oboInOwl:hasExactSynonym "dipolar aprotic solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48358" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "polar aprotic solvent" ; rdfs:subClassOf obo:CHEBI_48354, obo:CHEBI_48357 . obo:CHEBI_48359 obo:IAO_0000115 "Solvent that is capable of acting as a hydron (proton) acceptor." ; oboInOwl:hasExactSynonym "protophilic solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "HBA solvent", "hydrogen bond acceptor solvent" ; oboInOwl:id "CHEBI:48359" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "protophilic solvent" ; rdfs:subClassOf obo:CHEBI_39142, obo:CHEBI_48354 . obo:CHEBI_48360 obo:IAO_0000115 "Self-ionizing solvent possessing both characteristics of Bronsted acids and bases." ; oboInOwl:hasExactSynonym "amphiprotic solvent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48360" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amphiprotic solvent" ; rdfs:subClassOf obo:CHEBI_48356, obo:CHEBI_48359 . obo:CHEBI_48376 chebi:charge "0" ; chebi:formula "CH4N2O" ; chebi:inchi "InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)" ; chebi:inchikey "XSQUKJJJFZCRTK-UHFFFAOYSA-N" ; chebi:mass "60.05534" ; chebi:monoisotopicmass "60.03236" ; chebi:smiles "NC(O)=N" ; oboInOwl:hasDbXref "Beilstein:773698", "CAS:4744-36-9" ; oboInOwl:hasExactSynonym "carbamimidic acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2N-C(=NH)-OH", "H2N-C(OH)=NH", "HO-C(=NH)-NH2", "Isoharnstoff", "carbamimic acid", "carbonamidimidic acid", "isourea", "pseudourea" ; oboInOwl:id "CHEBI:48376" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbamimidic acid" ; rdfs:subClassOf obo:CHEBI_48379, obo:CHEBI_64708, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16199 ] . obo:CHEBI_48377 obo:IAO_0000115 "Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH)." ; oboInOwl:hasExactSynonym "imidic acid", "imidic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "imidic acids", "imino acids" ; oboInOwl:id "CHEBI:48377" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "imidic acid" ; rdfs:subClassOf obo:CHEBI_33241, obo:CHEBI_51143 . obo:CHEBI_48378 oboInOwl:hasExactSynonym "carboximidic acid", "carboximidic acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carboximidic acids" ; oboInOwl:id "CHEBI:48378" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carboximidic acid" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_48377 . obo:CHEBI_48379 obo:IAO_0000115 "A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives." ; oboInOwl:hasExactSynonym "isoureas" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "isoureas" ; oboInOwl:id "CHEBI:48379" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isourea" ; rdfs:subClassOf obo:CHEBI_48378 . obo:CHEBI_48539 obo:IAO_0000115 "Any drug that acts on an alpha-adrenergic receptor." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-adrenergic drugs" ; oboInOwl:id "CHEBI:48539" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-adrenergic drug" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_48540 obo:IAO_0000115 "Any of the drugs that act on beta-adrenergic receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "beta-adrenergic drugs" ; oboInOwl:id "CHEBI:48540" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "beta-adrenergic drug" ; rdfs:subClassOf obo:CHEBI_37962 . obo:CHEBI_48544 obo:IAO_0000115 "Esters or salts of methanesulfonic acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:48544" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methanesulfonates" ; rdfs:subClassOf obo:CHEBI_33261, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_27376 ] . obo:CHEBI_48560 obo:IAO_0000115 "A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dopamine agent", "dopamine agents", "dopamine drug", "dopamine drugs", "dopaminergic agents" ; oboInOwl:id "CHEBI:48560" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dopaminergic agent" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_48561 obo:IAO_0000115 "A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dopamine antagonist", "dopamine blocker", "dopamine receptor antagonist", "dopaminergic antagonists" ; oboInOwl:id "CHEBI:48561" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dopaminergic antagonist" ; rdfs:subClassOf obo:CHEBI_48560, obo:CHEBI_48706 . obo:CHEBI_48578 obo:IAO_0000115 "A role played by a substance that can react readily with, and thereby eliminate, radicals." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "free radical scavengers", "free-radical scavenger" ; oboInOwl:id "CHEBI:48578" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "radical scavenger" ; rdfs:subClassOf obo:CHEBI_22586 . obo:CHEBI_48705 obo:IAO_0000115 "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own." ; oboInOwl:hasExactSynonym "agonist" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agonista", "agoniste", "agonists" ; oboInOwl:id "CHEBI:48705" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "agonist" ; rdfs:subClassOf obo:CHEBI_52210 . obo:CHEBI_48706 obo:IAO_0000115 "Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances." ; oboInOwl:hasExactSynonym "antagonist" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antagonista", "antagoniste", "antagonists" ; oboInOwl:id "CHEBI:48706" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antagonist" ; rdfs:subClassOf obo:CHEBI_52210 . obo:CHEBI_48854 chebi:charge "0" ; chebi:formula "H2O3S" ; chebi:inchi "InChI=1S/H2O3S/c1-4(2)3/h(H2,1,2,3)" ; chebi:inchikey "LSNNMFCWUKXFEE-UHFFFAOYSA-N" ; chebi:mass "82.08008" ; chebi:monoisotopicmass "81.97247" ; chebi:smiles "OS(O)=O" ; oboInOwl:hasAlternativeId "CHEBI:26837", "CHEBI:9344" ; oboInOwl:hasDbXref "CAS:7782-99-2", "Gmelin:1458", "KEGG:C00094", "KNApSAcK:C00019662", "PDBeChem:SO3", "UM-BBD_compID:c0348" ; oboInOwl:hasExactSynonym "Sulfurous acid", "dihydrogen trioxosulfate", "dihydroxidooxidosulfur", "sulfurous acid", "trioxosulfuric acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2SO3", "S(O)(OH)2", "Sulfite", "[SO(OH)2]", "acide sulfureux", "acido sulfuroso", "schweflige Saeure", "sulphurous acid" ; oboInOwl:id "CHEBI:48854" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfurous acid" ; rdfs:subClassOf obo:CHEBI_33402, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17137 ], [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_29214 ] . obo:CHEBI_4887 obo:IAO_0000115 "A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures." ; chebi:charge "0" ; chebi:formula "C7H11NO2" ; chebi:inchi "InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)" ; chebi:inchikey "HAPOVYFOVVWLRS-UHFFFAOYSA-N" ; chebi:mass "141.16770" ; chebi:monoisotopicmass "141.07898" ; chebi:smiles "CCC1(C)CC(=O)NC1=O" ; oboInOwl:hasAlternativeId "CHEBI:131811" ; oboInOwl:hasDbXref "CAS:77-67-8", "Chemspider:3175", "DrugBank:DB00593", "Drug_Central:1087", "HMDB:HMDB0014731", "KEGG:C07505", "KEGG:D00539", "LINCS:LSM-5195", "PMID:12873507", "PMID:16606760", "PMID:1681105", "PMID:17011080", "PMID:17046248", "PMID:17451232", "PMID:17481896", "PMID:1847429", "PMID:18949032", "PMID:19005061", "PMID:1992141", "PMID:2061925", "PMID:21332949", "PMID:21945797", "PMID:2296016", "PMID:2308142", "PMID:3336019", "PMID:3820228", "PMID:8246220", "PMID:8627613", "PMID:8691481", "PMID:9016327", "Reaxys:117054", "Wikipedia:Ethosuximide" ; oboInOwl:hasExactSynonym "3-ethyl-3-methylpyrrolidine-2,5-dione", "Ethosuximide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+-)-2-ethyl-2-methylsuccinimide", "2-ethyl-2-methylsuccinimide", "2-methyl-2-ethylsuccinimide", "3-ethyl-3-methyl-2,5-pyrrolidinedione", "3-ethyl-3-methylsuccinimide", "3-methyl-3-ethylpyrrolidine-2,5-dione", "3-methyl-3-ethylsuccinimide", "Aethosuximide", "alpha-ethyl-alpha-methylsuccinimide", "alpha-methyl-alpha-ethylsuccinimide", "ethosuximide", "ethosuximidum", "etosuximida", "gamma-ethyl-gamma-methyl-succinimide", "gamma-methyl-gamma-ethyl-succinimide" ; oboInOwl:id "CHEBI:4887" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ethosuximide" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35356, obo:CHEBI_38275, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_194338 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35623 ] . obo:CHEBI_48909 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "imidazothiazoles" ; oboInOwl:id "CHEBI:48909" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "imidazothiazole" ; rdfs:subClassOf obo:CHEBI_27171, obo:CHEBI_38101, obo:CHEBI_38106 . obo:CHEBI_48975 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "substituted anilines" ; oboInOwl:id "CHEBI:48975" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "substituted aniline" ; rdfs:subClassOf obo:CHEBI_22562 . obo:CHEBI_49110 obo:IAO_0000115 "A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "peripheral nervous system agent", "peripheral nervous system drugs" ; oboInOwl:id "CHEBI:49110" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "peripheral nervous system drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_49200 obo:IAO_0000115 "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H(+)/K(+)-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors." ; oboInOwl:hasDbXref "Wikipedia:Proton_pump_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(K(+) + H(+))-ATPase inhibitor", "(K(+) + H(+))-ATPase inhibitors", "ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitor", "ATP phosphohydrolase (H(+)/K(+)-exchanging) inhibitors", "EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitors", "EC 3.6.3.10 inhibitor", "EC 3.6.3.10 inhibitors", "H(+)-K(+)-ATPase inhibitor", "H(+)-K(+)-ATPase inhibitors", "H(+)/K(+)-ATPase inhibitor", "H(+)/K(+)-ATPase inhibitors", "H(+)/K(+)-exchanging ATPase inhibitor", "H(+)/K(+)-exchanging ATPase inhibitors", "H,K-ATPase inhibitor", "H,K-ATPase inhibitors", "proton pump inhibitor", "proton pump inhibitors" ; oboInOwl:id "CHEBI:49200" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76895 . obo:CHEBI_49637 chebi:charge "0" ; chebi:formula "H" ; chebi:inchi "InChI=1S/H" ; chebi:inchikey "YZCKVEUIGOORGS-UHFFFAOYSA-N" ; chebi:mass "1.00794" ; chebi:monoisotopicmass "1.00783" ; chebi:smiles "[H]" ; oboInOwl:hasAlternativeId "CHEBI:24634", "CHEBI:49636" ; oboInOwl:hasDbXref "WebElements:H" ; oboInOwl:hasExactSynonym "hydrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1H", "H", "Wasserstoff", "hidrogeno", "hydrogen", "hydrogene" ; oboInOwl:id "CHEBI:49637" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydrogen atom" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_24835, obo:CHEBI_25585, obo:CHEBI_33559, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33937 ] . obo:CHEBI_49870 chebi:charge "0" ; chebi:formula "H3O3Sb" ; chebi:inchi "InChI=1S/3H2O.Sb/h3*1H2;/q;;;+3/p-3" ; chebi:inchikey "SZOADBKOANDULT-UHFFFAOYSA-K" ; chebi:mass "172.78202" ; chebi:monoisotopicmass "171.91203" ; chebi:smiles "[H]O[Sb](O[H])O[H]" ; oboInOwl:hasAlternativeId "CHEBI:30296", "CHEBI:49869" ; oboInOwl:hasDbXref "DrugBank:DB02453", "Gmelin:558348", "PDBeChem:SBO" ; oboInOwl:hasExactSynonym "antimonous acid", "trihydroxidoantimony" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H3SbO3", "TRIHYDROXYANTIMONITE(III)", "[Sb(OH)3]", "stiborous acid" ; oboInOwl:id "CHEBI:49870" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimonous acid" ; rdfs:subClassOf obo:CHEBI_36920, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30297 ] . obo:CHEBI_50007 oboInOwl:hasExactSynonym "antimony coordination entity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimony coordination compounds", "antimony coordination entities" ; oboInOwl:id "CHEBI:50007" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimony coordination entity" ; rdfs:subClassOf obo:CHEBI_36919 . obo:CHEBI_50047 obo:IAO_0000115 "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic amino compounds" ; oboInOwl:id "CHEBI:50047" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic amino compound" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35352, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_39142 ], [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_16134 ] . obo:CHEBI_50112 obo:IAO_0000115 "Any hormone that is responsible for controlling sexual characteristics and reproductive function." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Geschlechtshormon", "Geschlechtshormone", "Sexualhormon", "Sexualhormone", "hormone sexuelle", "hormones sexuelles", "sex hormones" ; oboInOwl:id "CHEBI:50112" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sex hormone" ; rdfs:subClassOf obo:CHEBI_24621 . obo:CHEBI_50114 obo:IAO_0000115 "A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens." ; oboInOwl:hasDbXref "Wikipedia:Estrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Estrogene", "Oestrogen", "Oestrogene", "estrogene", "estrogenes", "estrogenes Hormon", "estrogeno", "estrogenos", "estrogens", "oestrogen", "oestrogene", "oestrogenes", "oestrogens" ; oboInOwl:id "CHEBI:50114" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "estrogen" ; rdfs:subClassOf obo:CHEBI_50112 . obo:CHEBI_50127 chebi:charge "0" ; chebi:formula "CF3" ; chebi:mass "69.00591" ; chebi:monoisotopicmass "68.99521" ; chebi:smiles "C(F)(*)(F)F" ; oboInOwl:hasExactSynonym "trifluoromethyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-CF3" ; oboInOwl:id "CHEBI:50127" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "trifluoromethyl group" ; rdfs:subClassOf obo:CHEBI_50491, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_38825 ], [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_41550 ] . obo:CHEBI_50177 obo:IAO_0000115 "A drug used to treat or prevent skin disorders or for the routine care of skin." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dermatologic agent", "dermatologic drugs", "dermatological agent" ; oboInOwl:id "CHEBI:50177" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dermatologic drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_50184 obo:IAO_0000115 "A compound which inhibits the movement of an ion across an energy-transducing cell membrane." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ion transport inhibitors", "ion-transport inhibitor", "ion-transport inhibitors" ; oboInOwl:id "CHEBI:50184" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ion transport inhibitor" ; rdfs:subClassOf obo:CHEBI_38632 . obo:CHEBI_50218 obo:IAO_0000115 "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*)." ; oboInOwl:hasAlternativeId "CHEBI:76774" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.4.* (phosphoric diester hydrolase) inhibitors", "phosphodiesterase inhibitor", "phosphodiesterase inhibitors", "phosphoric diester hydrolase (EC 3.1.4.*) inhibitor", "phosphoric diester hydrolase (EC 3.1.4.*) inhibitors", "phosphoric diester hydrolase inhibitor", "phosphoric diester hydrolase inhibitors" ; oboInOwl:id "CHEBI:50218" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.1.4.* (phosphoric diester hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76760 . obo:CHEBI_50266 obo:IAO_0000115 "A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug." ; oboInOwl:hasDbXref "PMID:23993918", "PMID:23998799", "PMID:24329110", "PMID:24628402", "PMID:24709544", "PMID:25144792", "PMID:25157234", "PMID:25269430", "PMID:25391982", "PMID:25591121", "PMID:25620096", "PMID:25795057", "PMID:26028253", "PMID:26184144", "PMID:28070577", "PMID:28215138", "PMID:28219047", "PMID:28259775", "PMID:28319647", "PMID:28329729", "PMID:28334528", "Wikipedia:Prodrug" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Prodrugs" ; oboInOwl:id "CHEBI:50266" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "prodrug" ; rdfs:subClassOf obo:CHEBI_136859, obo:CHEBI_23888 . obo:CHEBI_50267 obo:IAO_0000115 "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "chemoprotectant", "chemoprotectants", "chemoprotective agent", "chemoprotective agents", "protective agents" ; oboInOwl:id "CHEBI:50267" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "protective agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_50297 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical nucleotide residues" ; oboInOwl:id "CHEBI:50297" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "canonical nucleotide residue" ; rdfs:subClassOf obo:CHEBI_50319 . obo:CHEBI_50299 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical ribonucleotide residues" ; oboInOwl:id "CHEBI:50299" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "canonical ribonucleotide residue" ; rdfs:subClassOf obo:CHEBI_50297 . obo:CHEBI_50312 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:50312" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "onium compound" ; rdfs:subClassOf obo:CHEBI_37577 . obo:CHEBI_50313 obo:IAO_0000115 "Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families." ; oboInOwl:hasExactSynonym "onium cations" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "onium cations", "onium ion", "onium ions" ; oboInOwl:id "CHEBI:50313" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "onium cation" ; rdfs:subClassOf obo:CHEBI_50312 . obo:CHEBI_50314 chebi:charge "+1" ; chebi:formula "FH2" ; chebi:inchi "InChI=1S/FH2/h1H2/q+1" ; chebi:inchikey "YNESUKSMQODWNS-UHFFFAOYSA-N" ; chebi:mass "21.01428" ; chebi:monoisotopicmass "21.01350" ; chebi:smiles "[H][F+][H]" ; oboInOwl:hasExactSynonym "fluoranium", "fluoronium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2F(+)", "[FH2](+)" ; oboInOwl:id "CHEBI:50314" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluoronium" ; rdfs:subClassOf obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_29228 ] . obo:CHEBI_50315 chebi:charge "+1" ; chebi:formula "ClH2" ; chebi:inchi "InChI=1S/ClH2/h1H2/q+1" ; chebi:inchikey "IGJWHVUMEJASKV-UHFFFAOYSA-N" ; chebi:mass "37.46858" ; chebi:monoisotopicmass "36.98395" ; chebi:smiles "[H][Cl+][H]" ; oboInOwl:hasDbXref "Gmelin:331" ; oboInOwl:hasExactSynonym "chloranium", "chloronium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2Cl(+)", "[ClH2](+)" ; oboInOwl:id "CHEBI:50315" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chloronium" ; rdfs:subClassOf obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17883 ] . obo:CHEBI_50316 chebi:charge "+1" ; chebi:formula "BrH2" ; chebi:inchi "InChI=1S/BrH2/h1H2/q+1" ; chebi:inchikey "IWNNBBVLEFUBNE-UHFFFAOYSA-N" ; chebi:mass "81.91988" ; chebi:monoisotopicmass "80.93344" ; chebi:smiles "[H][Br+][H]" ; oboInOwl:hasDbXref "Gmelin:719134" ; oboInOwl:hasExactSynonym "bromanium", "bromonium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2Br(+)", "[BrH2](+)" ; oboInOwl:id "CHEBI:50316" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bromonium" ; rdfs:subClassOf obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_47266 ] . obo:CHEBI_50317 chebi:charge "+1" ; chebi:formula "H2I" ; chebi:inchi "InChI=1S/H2I/h1H2/q+1" ; chebi:inchikey "MGFYSGNNHQQTJW-UHFFFAOYSA-N" ; chebi:mass "128.92035" ; chebi:monoisotopicmass "128.91957" ; chebi:smiles "[H][I+][H]" ; oboInOwl:hasDbXref "Gmelin:1425841" ; oboInOwl:hasExactSynonym "iodanium", "iodonium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2I(+)", "[IH2](+)" ; oboInOwl:id "CHEBI:50317" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "iodonium" ; rdfs:subClassOf obo:CHEBI_50313, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_43451 ] . obo:CHEBI_50319 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleotide residues" ; oboInOwl:id "CHEBI:50319" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleotide residue" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_50320 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleoside residues" ; oboInOwl:id "CHEBI:50320" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside residue" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_50325 obo:IAO_0000115 "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical amino-acid side-chain", "canonical amino-acid side-chains", "proteinogenic amino-acid side-chain", "proteinogenic amino-acid side-chain groups", "proteinogenic amino-acid side-chains" ; oboInOwl:id "CHEBI:50325" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "proteinogenic amino-acid side-chain group" ; rdfs:subClassOf obo:CHEBI_33249 . obo:CHEBI_50326 chebi:charge "0" ; chebi:formula "CH3S" ; chebi:mass "47.10052" ; chebi:monoisotopicmass "46.99555" ; chebi:smiles "SC*" ; oboInOwl:hasExactSynonym "sulfanylmethyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "-CH2-SH", "HS-CH2-", "cysteine side-chain" ; oboInOwl:id "CHEBI:50326" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfanylmethyl group" ; rdfs:subClassOf obo:CHEBI_50325 . obo:CHEBI_50339 chebi:charge "0" ; chebi:formula "C4H10N" ; chebi:mass "72.12894" ; chebi:monoisotopicmass "72.08132" ; chebi:smiles "NCCCC*" ; oboInOwl:hasExactSynonym "4-aminobutyl" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "lysine side-chain" ; oboInOwl:id "CHEBI:50339" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "4-aminobutyl group" ; rdfs:subClassOf obo:CHEBI_50325, [ a owl:Restriction ; owl:onProperty chebi5:is_substituent_group_from ; owl:someValuesFrom obo:CHEBI_43799 ] . obo:CHEBI_50344 obo:IAO_0000115 "Any of the macrolides obtained as fermentation products from the bacterium Streptomyces avermitilis and consisting of a 16-membered macrocyclic backbone that is fused both benzofuran and spiroketal functions and contains a disaccharide substituent. They have significant anthelmintic and insecticidal properties." ; oboInOwl:hasDbXref "PMID:22039784", "PMID:22039799", "PMID:22542398", "PMID:23165468", "PMID:8688633", "Wikipedia:Avermectin" ; oboInOwl:hasExactSynonym "avermectin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "avermectins" ; oboInOwl:id "CHEBI:50344" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "avermectin" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25106, obo:CHEBI_59779, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76969 ] . obo:CHEBI_50356 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic iodide salts" ; oboInOwl:id "CHEBI:50356" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic iodide salt" ; rdfs:subClassOf obo:CHEBI_24858, obo:CHEBI_51069 . obo:CHEBI_50491 obo:IAO_0000115 "A group derived from a haloalkane by removal of a hydrogen atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "haloalkyl groups" ; oboInOwl:id "CHEBI:50491" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "haloalkyl group" ; rdfs:subClassOf obo:CHEBI_33249 . obo:CHEBI_50511 obo:IAO_0000115 "Compounds containing a bipyridine group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bipyridyls" ; oboInOwl:id "CHEBI:50511" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bipyridines" ; rdfs:subClassOf obo:CHEBI_36820, obo:CHEBI_38101, obo:CHEBI_64459 . obo:CHEBI_50523 obo:IAO_0000115 "A gamma-lactone that consists of a 2-furanone skeleton and its substituted derivatives." ; chebi:charge "0" ; chebi:formula "C4H4O2" ; chebi:mass "84.074" ; chebi:monoisotopicmass "84.02113" ; oboInOwl:hasAlternativeId "CHEBI:22960", "CHEBI:38121" ; oboInOwl:hasDbXref "Wikipedia:Butenolide" ; oboInOwl:hasExactSynonym "furan-2-one" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-furanone", "butenolides" ; oboInOwl:id "CHEBI:50523" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "butenolide" ; rdfs:subClassOf obo:CHEBI_24129, obo:CHEBI_37581 . obo:CHEBI_50584 obo:IAO_0000115 "An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position." ; oboInOwl:hasAlternativeId "CHEBI:22937", "CHEBI:50581" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alkyl alcohols", "hydroxyalkane", "hydroxyalkanes" ; oboInOwl:id "CHEBI:50584" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alkyl alcohol" ; rdfs:subClassOf obo:CHEBI_2571 . obo:CHEBI_50733 obo:IAO_0000115 "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Dietary Supplement", "Food Supplementation", "Nutritional supplement" ; oboInOwl:id "CHEBI:50733" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nutraceutical" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_50795 obo:IAO_0000115 "A nanometre sized object." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nanoestructura" ; oboInOwl:id "CHEBI:50795" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nanostructure" ; rdfs:subClassOf obo:CHEBI_36357 . obo:CHEBI_50803 obo:IAO_0000115 "A nanosized spherical or capsule-shaped structure." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NP", "Nanoteilchen", "nanoparticles", "nanoparticula", "nanoparticule" ; oboInOwl:id "CHEBI:50803" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nanoparticle" ; rdfs:subClassOf obo:CHEBI_50795 . obo:CHEBI_50826 obo:IAO_0000115 "A nanoparticle consisting of silver atoms." ; chebi:charge "0" ; chebi:formula "Ag" ; chebi:mass "107.868" ; chebi:monoisotopicmass "106.90510" ; oboInOwl:hasDbXref "PMID:22128035", "PMID:22148238", "Wikipedia:Silver_nanoparticles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ag nanoparticle", "Ag nanoparticles", "AgNP", "silver nanoparticles" ; oboInOwl:id "CHEBI:50826" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "silver nanoparticle" ; rdfs:subClassOf obo:CHEBI_33966, obo:CHEBI_52855 . obo:CHEBI_50846 obo:IAO_0000115 "Biologically active substance whose activity affects or plays a role in the functioning of the immune system." ; oboInOwl:hasDbXref "Wikipedia:Immunotherapy" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Biomodulator", "Immune factor", "Immunologic factor", "Immunological factor", "immunomodulators" ; oboInOwl:id "CHEBI:50846" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "immunomodulator" ; rdfs:subClassOf obo:CHEBI_23888, obo:CHEBI_24432 . obo:CHEBI_50847 obo:IAO_0000115 "A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity." ; oboInOwl:hasDbXref "Wikipedia:Immunologic_adjuvant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Immunoactivator", "Immunoadjuvant", "Immunologic adjuvant", "Immunopotentiator", "Immunostimulant" ; oboInOwl:id "CHEBI:50847" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "immunological adjuvant" ; rdfs:subClassOf obo:CHEBI_50846, obo:CHEBI_60809 . obo:CHEBI_50857 obo:IAO_0000115 "A drug used to treat allergic reactions." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-allergic agents", "anti-allergic drug", "anti-allergic drugs" ; oboInOwl:id "CHEBI:50857" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anti-allergic agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_50860 obo:IAO_0000115 "Any molecular entity that contains carbon." ; oboInOwl:hasAlternativeId "CHEBI:25700", "CHEBI:33244" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic compounds", "organic entity", "organic molecular entities" ; oboInOwl:id "CHEBI:50860" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic molecular entity" ; rdfs:subClassOf obo:CHEBI_33582, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_27594 ] . obo:CHEBI_50893 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "azaarenes" ; oboInOwl:id "CHEBI:50893" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "azaarene" ; rdfs:subClassOf obo:CHEBI_33833, obo:CHEBI_38101 . obo:CHEBI_50902 obo:IAO_0000115 "A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells." ; oboInOwl:hasDbXref "Wikipedia:Genotoxicity" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "genotoxic agent", "genotoxic agents", "genotoxins" ; oboInOwl:id "CHEBI:50902" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "genotoxin" ; rdfs:subClassOf obo:CHEBI_52209 . obo:CHEBI_50903 obo:IAO_0000115 "A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agente carcinogeno", "cancerigene", "cancerogene", "carcinogen", "carcinogene", "carcinogenic agents", "carcinogeno", "carcinogens" ; oboInOwl:id "CHEBI:50903" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carcinogenic agent" ; rdfs:subClassOf obo:CHEBI_52209 . obo:CHEBI_50904 obo:IAO_0000115 "A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy." ; oboInOwl:hasDbXref "Wikipedia:Allergen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alergeno", "allergene", "allergenic agent" ; oboInOwl:id "CHEBI:50904" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "allergen" ; rdfs:subClassOf obo:CHEBI_52209 . obo:CHEBI_50905 obo:IAO_0000115 "A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agent teratogene", "teratogen", "teratogeno" ; oboInOwl:id "CHEBI:50905" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "teratogenic agent" ; rdfs:subClassOf obo:CHEBI_52209 . obo:CHEBI_50906 obo:IAO_0000115 "A role is particular behaviour which a material entity may exhibit." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:50906" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "role" . obo:CHEBI_50910 obo:IAO_0000115 "A poison that interferes with the functions of the nervous system." ; oboInOwl:hasAlternativeId "CHEBI:50911" ; oboInOwl:hasDbXref "Wikipedia:Neurotoxin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "agente neurotoxico", "nerve poison", "nerve poisons", "neurotoxic agent", "neurotoxic agents", "neurotoxicant", "neurotoxins" ; oboInOwl:id "CHEBI:50910" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "neurotoxin" ; rdfs:subClassOf obo:CHEBI_52209, obo:CHEBI_64909 . obo:CHEBI_50925 obo:IAO_0000115 "An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine." ; oboInOwl:hasAlternativeId "CHEBI:75764" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "A-kinase inhibitor", "A-kinase inhibitors", "AP50 kinase inhibitor", "AP50 kinase inhibitors", "ATP-protein transphosphorylase inhibitor", "ATP-protein transphosphorylase inhibitors", "ATP:protein phosphotransferase (non-specific) inhibitor", "ATP:protein phosphotransferase (non-specific) inhibitors", "BR serine/threonine-protein kinase 2 inhibitor", "BR serine/threonine-protein kinase 2 inhibitors", "CK-2 inhibitor", "CK-2 inhibitors", "CKI inhibitor", "CKI inhibitors", "CKII inhibitor", "CKII inhibitors", "EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitors", "EC 2.7.11.1 inhibitor", "EC 2.7.11.1 inhibitors", "HIPK2 inhibitor", "HIPK2 inhibitors", "Hpr kinase inhibitor", "Hpr kinase inhibitors", "M phase-specific cdc2 kinase inhibitor", "M phase-specific cdc2 kinase inhibitors", "MKNK2 inhibitor", "MKNK2 inhibitors", "PAK-1 inhibitor", "PAK-1 inhibitors", "PAK1 inhibitor", "PAK1 inhibitors", "PKA inhibitor", "PKA inhibitors", "Prp4 protein kinase inhibitor", "Prp4 protein kinase inhibitors", "Raf kinase inhibitor", "Raf kinase inhibitors", "Raf-1 inhibitor", "Raf-1 inhibitors", "STK32 inhibitor", "STK32 inhibitors", "T-antigen kinase inhibitor", "T-antigen kinase inhibitors", "WEE1Hu inhibitor", "WEE1Hu inhibitors", "Wee 1-like kinase inhibitor", "Wee 1-like kinase inhibitors", "Wee-kinase inhibitor", "Wee-kinase inhibitors", "betaIIPKC inhibitor", "betaIIPKC inhibitors", "cAMP-dependent protein kinase A inhibitor", "cAMP-dependent protein kinase A inhibitors", "cAMP-dependent protein kinase inhibitor", "cAMP-dependent protein kinase inhibitors", "cGMP-dependent protein kinase inhibitor", "cGMP-dependent protein kinase inhibitors", "calcium-dependent protein kinase C inhibitor", "calcium-dependent protein kinase C inhibitors", "calcium/phospholipid-dependent protein kinase inhibitor", "calcium/phospholipid-dependent protein kinase inhibitors", "casein kinase (phosphorylating) inhibitor", "casein kinase (phosphorylating) inhibitors", "casein kinase 2 inhibitor", "casein kinase 2 inhibitors", "casein kinase I inhibitor", "casein kinase I inhibitors", "casein kinase II inhibitor", "casein kinase II inhibitors", "casein kinase inhibitor", "casein kinase inhibitors", "cyclic AMP-dependent protein kinase A inhibitor", "cyclic AMP-dependent protein kinase A inhibitors", "cyclic AMP-dependent protein kinase inhibitor", "cyclic AMP-dependent protein kinase inhibitors", "cyclic monophosphate-dependent protein kinase inhibitor", "cyclic monophosphate-dependent protein kinase inhibitors", "cyclic nucleotide-dependent protein kinase inhibitor", "cyclic nucleotide-dependent protein kinase inhibitors", "cyclin-dependent kinase inhibitor", "cyclin-dependent kinase inhibitors", "dsk1 inhibitor", "dsk1 inhibitors", "epsilon PKC inhibitor", "epsilon PKC inhibitors", "glycogen synthase a kinase inhibitor", "glycogen synthase a kinase inhibitors", "glycogen synthase kinase inhibitor", "glycogen synthase kinase inhibitors", "hydroxyalkyl-protein kinase inhibitor", "hydroxyalkyl-protein kinase inhibitors", "mitogen-activated S6 kinase inhibitor", "mitogen-activated S6 kinase inhibitors", "non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitor", "non-specific serine/threonine protein kinase (EC 2.7.11.1) inhibitors", "non-specific serine/threonine protein kinase inhibitor", "non-specific serine/threonine protein kinase inhibitors", "p21 activated kinase-1 inhibitor", "p21 activated kinase-1 inhibitors", "p82 kinase inhibitor", "p82 kinase inhibitors", "phosphorylase b kinase kinase inhibitor", "phosphorylase b kinase kinase inhibitors", "protein glutamyl kinase inhibitor", "protein glutamyl kinase inhibitors", "protein kinase (phosphorylating) inhibitor", "protein kinase (phosphorylating) inhibitors", "protein kinase A inhibitor", "protein kinase A inhibitors", "protein kinase CK2 inhibitor", "protein kinase CK2 inhibitors", "protein kinase p58 inhibitor", "protein kinase p58 inhibitors", "protein phosphokinase inhibitor", "protein phosphokinase inhibitors", "protein serine kinase inhibitor", "protein serine kinase inhibitors", "protein serine-threonine kinase inhibitor", "protein serine-threonine kinase inhibitors", "protein-aspartyl kinase inhibitor", "protein-aspartyl kinase inhibitors", "protein-cysteine kinase inhibitor", "protein-cysteine kinase inhibitors", "protein-serine kinase inhibitor", "protein-serine kinase inhibitors", "protein-serine/threonine kinase inhibitors", "ribosomal S6 protein kinase inhibitor", "ribosomal S6 protein kinase inhibitors", "ribosomal protein S6 kinase II inhibitor", "ribosomal protein S6 kinase II inhibitors", "serine kinase inhibitor", "serine kinase inhibitors", "serine protein kinase inhibitor", "serine protein kinase inhibitors", "serine(threonine) protein kinase inhibitor", "serine(threonine) protein kinase inhibitors", "serine-specific protein kinase inhibitor", "serine-specific protein kinase inhibitors", "serine/threonine protein kinase inhibitor", "serine/threonine protein kinase inhibitors", "threonine-specific protein kinase inhibitor", "threonine-specific protein kinase inhibitors", "twitchin kinase inhibitor", "twitchin kinase inhibitors", "type-2 casein kinase inhibitor", "type-2 casein kinase inhibitors" ; oboInOwl:id "CHEBI:50925" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76812 . obo:CHEBI_50949 obo:IAO_0000115 "A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent." ; oboInOwl:hasDbXref "Wikipedia:Selective_serotonin_reuptake_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "SSRI", "serotonin reuptake inhibitor" ; oboInOwl:id "CHEBI:50949" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "serotonin uptake inhibitor" ; rdfs:subClassOf obo:CHEBI_48278 . obo:CHEBI_50994 obo:IAO_0000115 "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "primary amino compounds" ; oboInOwl:id "CHEBI:50994" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "primary amino compound" ; rdfs:subClassOf obo:CHEBI_50047, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_65296 ] . obo:CHEBI_50995 obo:IAO_0000115 "A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "secondary amino compounds" ; oboInOwl:id "CHEBI:50995" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "secondary amino compound" ; rdfs:subClassOf obo:CHEBI_50047 . obo:CHEBI_50996 obo:IAO_0000115 "A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tertiary amino compounds" ; oboInOwl:id "CHEBI:50996" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tertiary amino compound" ; rdfs:subClassOf obo:CHEBI_50047, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_137982 ] . obo:CHEBI_51026 obo:IAO_0000115 "A cyclic compound containing nine or more atoms as part of the cyclic system." ; oboInOwl:hasDbXref "Wikipedia:Macrocycle" ; oboInOwl:hasExactSynonym "macrocycle" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Makrocyclen", "Makrozyklen", "macrocycles", "makrocyclische Verbindungen", "makrozyklische Verbindungen" ; oboInOwl:id "CHEBI:51026" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "macrocycle" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_51061 obo:IAO_0000115 "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "hormone receptor modulators" ; oboInOwl:id "CHEBI:51061" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hormone receptor modulator" ; rdfs:subClassOf obo:CHEBI_90710 . obo:CHEBI_51069 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic halide salts" ; oboInOwl:id "CHEBI:51069" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic halide salt" ; rdfs:subClassOf obo:CHEBI_24868 . obo:CHEBI_51074 obo:IAO_0000115 "A colchicine that has (R)-configuration." ; chebi:charge "0" ; chebi:formula "C22H25NO6" ; chebi:inchi "InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m1/s1" ; chebi:inchikey "IAKHMKGGTNLKSZ-MRXNPFEDSA-N" ; chebi:mass "399.43704" ; chebi:monoisotopicmass "399.16819" ; chebi:smiles "COc1cc2CC[C@@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC" ; oboInOwl:hasDbXref "Beilstein:3226657", "CAS:75520-89-7", "Chemspider:48121", "PMID:28959419", "PMID:7265112" ; oboInOwl:hasExactSynonym "N-[(7R)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-colchicine", "(R)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide" ; oboInOwl:id "CHEBI:51074" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(R)-colchicine" ; rdfs:subClassOf obo:CHEBI_23359, [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_27882 ] . obo:CHEBI_51086 obo:IAO_0000115 "A role played by the molecular entity or part thereof within a chemical context." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51086" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chemical role" ; rdfs:subClassOf obo:CHEBI_50906 . obo:CHEBI_51137 obo:IAO_0000115 "A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere." ; chebi:charge "0" ; chebi:formula "C18H20N2" ; chebi:inchi "InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3" ; chebi:inchikey "UEQUQVLFIPOEMF-UHFFFAOYSA-N" ; chebi:mass "264.36480" ; chebi:monoisotopicmass "264.16265" ; chebi:smiles "CN1CCN2C(C1)c1ccccc1Cc1ccccc21" ; oboInOwl:hasDbXref "Beilstein:755346", "CAS:24219-97-4", "DrugBank:DB06148", "Drug_Central:1796", "LINCS:LSM-1374", "PMID:18033297", "PMID:20825390", "Patent:NL6603256", "Patent:US3534041", "Wikipedia:Mianserin" ; oboInOwl:hasExactSynonym "2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine", "mianserin", "mianserina", "mianserine", "mianserinum" ; oboInOwl:id "CHEBI:51137" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mianserin" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_47804, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35640 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35678 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35717 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37890 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37955 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48279 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76779 ] . obo:CHEBI_51143 oboInOwl:hasAlternativeId "CHEBI:25556", "CHEBI:7594" ; oboInOwl:hasDbXref "KEGG:C06061" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Nitrogenous compounds", "nitrogen compounds", "nitrogen molecular entities" ; oboInOwl:id "CHEBI:51143" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nitrogen molecular entity" ; rdfs:subClassOf obo:CHEBI_33302, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_25555 ] . obo:CHEBI_51151 obo:IAO_0000115 "An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dipolar compounds" ; oboInOwl:id "CHEBI:51151" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dipolar compound" ; rdfs:subClassOf obo:CHEBI_72695 . obo:CHEBI_5118 obo:IAO_0000115 "A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine. A selective serotonin reuptake inhibitor (SSRI), it is used (generally as the hydrochloride salt) for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder." ; chebi:charge "0" ; chebi:formula "C17H18F3NO" ; chebi:mass "309.32610" ; chebi:monoisotopicmass "309.13405" ; oboInOwl:hasDbXref "Beilstein:39914106", "CAS:54910-89-3", "DrugBank:DB00472", "HMDB:HMDB0014615", "KEGG:D00326", "PMID:19144769", "PMID:22903652", "PMID:22923967", "PMID:23885544", "PMID:24184049", "PMID:24399719", "PMID:24464553", "PMID:24997906", "PMID:25448156", "PMID:25639887", "PMID:25671301", "PMID:8694321", "Patent:DE2500110", "Patent:US4314081", "Reaxys:3991406", "Wikipedia:Fluoxetine" ; oboInOwl:hasExactSynonym "rac-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+-)-N-methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-p-tolyl)oxy)propylamine", "(+-)-N-methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine", "Prozac", "fluoxetina", "fluoxetine", "fluoxetinum" ; oboInOwl:id "CHEBI:5118" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fluoxetine" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_60911, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_86991 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_86992 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35480 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50949 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_88188 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_36810 ] . obo:CHEBI_51277 obo:IAO_0000115 "A compound of general formula RC(=O)SR'. Compare with thionoester, RC(=S)OR'." ; chebi:charge "0" ; chebi:formula "COSR2" ; chebi:mass "60.07500" ; chebi:monoisotopicmass "59.96699" ; chebi:smiles "[*]C(=O)S[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "thio ester", "thioesters", "thiol ester" ; oboInOwl:id "CHEBI:51277" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "thioester" ; rdfs:subClassOf obo:CHEBI_26959, obo:CHEBI_36586 . obo:CHEBI_51280 chebi:charge "0" ; chebi:formula "C3H6OS" ; chebi:inchi "InChI=1S/C3H6OS/c1-3(4)5-2/h1-2H3" ; chebi:inchikey "OATSQCXMYKYFQO-UHFFFAOYSA-N" ; chebi:mass "90.14514" ; chebi:monoisotopicmass "90.01394" ; chebi:smiles "CSC(C)=O" ; oboInOwl:hasAlternativeId "CHEBI:38533", "CHEBI:51279" ; oboInOwl:hasDbXref "Beilstein:1736664", "CAS:1534-08-3", "Gmelin:1316927" ; oboInOwl:hasExactSynonym "S-methyl ethanethioate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "CH3C(O)SCH3", "ethanethioic acid, S-methyl ester", "methanethiol acetate", "methyl ethanethioate", "methyl thioacetate", "methylthioacetate", "thioacetic acid S-methyl ester" ; oboInOwl:id "CHEBI:51280" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "S-methyl thioacetate" ; rdfs:subClassOf obo:CHEBI_51277, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16555 ] . obo:CHEBI_51323 obo:IAO_0000115 "An alkaloid based on a cinchonan skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cinchona alkaloids" ; oboInOwl:id "CHEBI:51323" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cinchona alkaloid" ; rdfs:subClassOf obo:CHEBI_26509 . obo:CHEBI_51371 obo:IAO_0000115 "A drug used to produce muscle relaxation (excepting neuromuscular blocking agents). Its primary clinical and therapeutic use is the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. Also used for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in multiple sclerosis." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "muscle relaxants" ; oboInOwl:id "CHEBI:51371" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "muscle relaxant" ; rdfs:subClassOf obo:CHEBI_51372 . obo:CHEBI_51372 obo:IAO_0000115 "A drug used for its actions on skeletal muscle." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51372" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "neuromuscular agent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_51373 obo:IAO_0000115 "A drug that binds to and activates gamma-aminobutyric acid receptors." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "GABA agonists", "GABA receptor agonist", "GABA receptor agonists", "gamma-aminobutyric acid receptor agonist", "gamma-aminobutyric acid receptor agonists" ; oboInOwl:id "CHEBI:51373" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "GABA agonist" ; rdfs:subClassOf obo:CHEBI_51374 . obo:CHEBI_51374 obo:IAO_0000115 "A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51374" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "GABA agent" ; rdfs:subClassOf obo:CHEBI_35942 . obo:CHEBI_51422 obo:IAO_0000115 "Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organodiyl groups" ; oboInOwl:id "CHEBI:51422" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organodiyl group" ; rdfs:subClassOf obo:CHEBI_51446 . obo:CHEBI_51446 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51446" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "organic divalent group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_51447 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:51447" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "organic univalent group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_51689 obo:IAO_0000115 "An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position." ; chebi:charge "0" ; chebi:formula "C3OR4" ; chebi:mass "52.03150" ; chebi:monoisotopicmass "51.99491" ; chebi:smiles "[*]\\C([*])=C(\\[*])C([*])=O" ; oboInOwl:hasDbXref "Wikipedia:Enone" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "enones" ; oboInOwl:id "CHEBI:51689" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "enone" ; rdfs:subClassOf obo:CHEBI_51721, obo:CHEBI_78840 . obo:CHEBI_51702 obo:IAO_0000115 "An alpha,beta-unsaturated carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position." ; chebi:charge "0" ; chebi:formula "C3O2R4" ; chebi:mass "68.03090" ; chebi:monoisotopicmass "67.98983" ; chebi:smiles "[*]\\C([*])=C(\\[*])C(=O)O[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "enoate", "enoate esters", "enoates" ; oboInOwl:id "CHEBI:51702" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "enoate ester" ; rdfs:subClassOf obo:CHEBI_51737, obo:CHEBI_78840 . obo:CHEBI_51721 obo:IAO_0000115 "A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha,beta-unsaturated ketones" ; oboInOwl:id "CHEBI:51721" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha,beta-unsaturated ketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_51737 obo:IAO_0000115 "A carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) or R(1)C#C-C(=O)OR(2) (R(2) =/= H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha,beta-unsaturated carboxylic esters" ; oboInOwl:id "CHEBI:51737" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha,beta-unsaturated carboxylic ester" ; rdfs:subClassOf obo:CHEBI_33308 . obo:CHEBI_51867 obo:IAO_0000115 "A ketone of formula RC(=O)CH3 (R =/= H)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methyl ketones" ; oboInOwl:id "CHEBI:51867" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methyl ketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_51869 obo:IAO_0000115 "A diketone that has its two ketone functionalities on adjacent atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-diketones" ; oboInOwl:id "CHEBI:51869" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-diketone" ; rdfs:subClassOf obo:CHEBI_46640 . obo:CHEBI_51958 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic polycyclic compounds" ; oboInOwl:id "CHEBI:51958" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic polycyclic compound" ; rdfs:subClassOf obo:CHEBI_33635, obo:CHEBI_33832 . obo:CHEBI_51959 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic tricyclic compounds" ; oboInOwl:id "CHEBI:51959" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic tricyclic compound" ; rdfs:subClassOf obo:CHEBI_51958 . obo:CHEBI_52090 obo:IAO_0000115 "An organic anion that is the conjugate base of methanol." ; chebi:charge "-1" ; chebi:formula "CH3O" ; chebi:inchi "InChI=1S/CH3O/c1-2/h1H3/q-1" ; chebi:inchikey "NBTOZLQBSIZIKS-UHFFFAOYSA-N" ; chebi:mass "31.03390" ; chebi:monoisotopicmass "31.01894" ; chebi:smiles "C[O-]" ; oboInOwl:hasDbXref "Reaxys:1839368" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methoxide ion" ; oboInOwl:id "CHEBI:52090" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methoxide" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17790 ] . obo:CHEBI_52092 obo:IAO_0000115 "An organic anion that is the conjugate base of ethanol." ; chebi:charge "-1" ; chebi:formula "C2H5O" ; chebi:inchi "InChI=1S/C2H5O/c1-2-3/h2H2,1H3/q-1" ; chebi:inchikey "HHFAWKCIHAUFRX-UHFFFAOYSA-N" ; chebi:mass "45.06050" ; chebi:monoisotopicmass "45.03459" ; chebi:smiles "CC[O-]" ; oboInOwl:hasDbXref "Beilstein:1839415", "Reaxys:1839415" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ethoxy anion" ; oboInOwl:id "CHEBI:52092" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ethoxide" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16236 ] . obo:CHEBI_52206 obo:IAO_0000115 "A biological role played by the molecular entity or part thereof within a biochemical context." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:52206" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "biochemical role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52208 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:52208" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "biophysical role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52209 obo:IAO_0000115 "A role played by the molecular entity or part thereof which causes the development of a pathological process." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "etiopathogenetic agent", "etiopathogenetic role" ; oboInOwl:id "CHEBI:52209" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aetiopathogenetic role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52210 obo:IAO_0000115 "A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:52210" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pharmacological role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52211 oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:52211" ; oboInOwl:inSubset chebi4:_STAR ; a owl:Class ; rdfs:label "physiological role" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52217 obo:IAO_0000115 "Any substance introduced into a living organism with therapeutic or diagnostic purpose." ; oboInOwl:hasAlternativeId "CHEBI:33293", "CHEBI:33294" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "farmaco", "medicament", "pharmaceuticals" ; oboInOwl:id "CHEBI:52217" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pharmaceutical" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_52290 obo:IAO_0000115 "A chemical substance that encourages a cell to commence cell division, triggering mitosis." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mitogens" ; oboInOwl:id "CHEBI:52290" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mitogen" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_52395 obo:IAO_0000115 "A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxyketones" ; oboInOwl:id "CHEBI:52395" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxyketone" ; rdfs:subClassOf obo:CHEBI_17087 . obo:CHEBI_52396 obo:IAO_0000115 "An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "alpha-oxyketones" ; oboInOwl:id "CHEBI:52396" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-oxyketone" ; rdfs:subClassOf obo:CHEBI_52395 . obo:CHEBI_52557 obo:IAO_0000115 "A diterpenoid with a tetracyclic skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tetracyclic diterpenoids" ; oboInOwl:id "CHEBI:52557" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tetracyclic diterpenoid" ; rdfs:subClassOf obo:CHEBI_23849 . obo:CHEBI_52837 oboInOwl:hasExactSynonym "quinolinium ion" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "quinolinium ions" ; oboInOwl:id "CHEBI:52837" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "quinolinium ion" ; rdfs:subClassOf obo:CHEBI_25697 . obo:CHEBI_52845 obo:IAO_0000115 "An organic group that consists of a closed ring. It may be a substituent or a skeleton." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic organic groups" ; oboInOwl:id "CHEBI:52845" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic organic group" ; rdfs:subClassOf obo:CHEBI_33247 . obo:CHEBI_52855 obo:IAO_0000115 "A nanoparticle that contains no carbon." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "inorganic nanoparticles" ; oboInOwl:id "CHEBI:52855" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "inorganic nanoparticle" ; rdfs:subClassOf obo:CHEBI_50803 . obo:CHEBI_53000 obo:IAO_0000115 "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antigenic determinant", "epitope function", "epitope role" ; oboInOwl:id "CHEBI:53000" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "epitope" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_53121 obo:IAO_0000115 "An antagonist at the A2A receptor." ; oboInOwl:hasDbXref "Wikipedia:Adenosine_A2A_receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenosine A2A receptor antagonists" ; oboInOwl:id "CHEBI:53121" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adenosine A2A receptor antagonist" ; rdfs:subClassOf obo:CHEBI_71232 . obo:CHEBI_53212 obo:IAO_0000115 "Organonitrogen compounds that are derivatives of isocyanic acid; compounds containing the isocyanate functional group -N=C=O (as opposed to the cyanate group, -O-C#N)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "iso-cyanates" ; oboInOwl:id "CHEBI:53212" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isocyanates" ; rdfs:subClassOf obo:CHEBI_35352, obo:CHEBI_36963, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_29202 ] . obo:CHEBI_55324 obo:IAO_0000115 "A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gastrointestinal agent", "gastrointestinal agents", "gastrointestinal drugs" ; oboInOwl:id "CHEBI:55324" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "gastrointestinal drug" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_55373 obo:IAO_0000115 "Oxazoles in which the N and O atoms are adjacent." ; oboInOwl:hasAlternativeId "CHEBI:46813" ; oboInOwl:hasExactSynonym "isoxazoles" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,2-oxazoles" ; oboInOwl:id "CHEBI:55373" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isoxazoles" ; rdfs:subClassOf obo:CHEBI_35790 . obo:CHEBI_55374 obo:IAO_0000115 "An oxazolidine containing one or more oxo groups." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxazolidinedione", "oxazolidinediones", "oxazolidinones" ; oboInOwl:id "CHEBI:55374" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxazolidinone" ; rdfs:subClassOf obo:CHEBI_38329 . obo:CHEBI_5615 obo:IAO_0000115 "A haloalkane comprising ethane having three flouro substituents at the 1-position as well as bromo- and chloro substituents at the 2-position." ; chebi:charge "0" ; chebi:formula "C2HBrClF3" ; chebi:inchi "InChI=1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H" ; chebi:inchikey "BCQZXOMGPXTTIC-UHFFFAOYSA-N" ; chebi:mass "197.38125" ; chebi:monoisotopicmass "195.89022" ; chebi:smiles "[H]C(Cl)(Br)C(F)(F)F" ; oboInOwl:hasDbXref "Beilstein:1736947", "CAS:151-67-7", "DrugBank:DB01159", "Drug_Central:1356", "Gmelin:793752", "KEGG:C07515", "KEGG:D00542", "PMID:7519986", "VSDB:1806", "Wikipedia:Halothane" ; oboInOwl:hasExactSynonym "2-bromo-2-chloro-1,1,1-trifluoroethane", "Halothane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1,1-trifluoro-2-bromo-2-chloroethane", "1,1,1-trifluoro-2-chloro-2-bromoethane", "1-bromo-1-chloro-2,2,2-trifluoroethane", "2,2,2-trifluoro-1-chloro-1-bromoethane", "2-bromo-2-chloro-1,1,1-trifluoroethane", "Fluothane", "Narcotane", "Phthorothanum", "Rhodialothan", "bromochlorotrifluoroethane" ; oboInOwl:id "CHEBI:5615" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "halothane" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_24469, obo:CHEBI_36683, obo:CHEBI_37141, obo:CHEBI_37143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38870 ] . obo:CHEBI_5686 obo:IAO_0000115 "A cyclic compound having as ring members atoms of at least two different elements." ; oboInOwl:hasExactSynonym "Heterocyclic compound" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "compuesto heterociclico", "compuestos heterociclicos", "heterocycle", "heterocyclic compounds" ; oboInOwl:id "CHEBI:5686" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "heterocyclic compound" ; rdfs:subClassOf obo:CHEBI_33595 . obo:CHEBI_57299 obo:IAO_0000115 "A ribonucleoside triphosphate oxoanion that is the trianion of adenosine 5'-triphosphate arising from deprotonation of three of the four free triphosphate OH groups." ; chebi:charge "-3" ; chebi:formula "C10H13N5O13P3" ; chebi:inchi "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/p-3/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "ZKHQWZAMYRWXGA-KQYNXXCUSA-K" ; chebi:mass "504.15720" ; chebi:monoisotopicmass "503.97392" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O" ; oboInOwl:hasDbXref "Beilstein:9535056" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:57299" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ATP(3-)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_59724, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78675 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_30616 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_15422 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_237958 ] . obo:CHEBI_57867 obo:IAO_0000115 "The conjugate base of a nucleoside 5'-phosphate." ; chebi:charge "-2" ; chebi:formula "C5H7O6PR2" ; chebi:mass "194.07920" ; chebi:monoisotopicmass "193.99802" ; chebi:smiles "O[C@H]1[C@@H]([*])[C@H]([*])O[C@@H]1COP([O-])([O-])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a nucleoside 5'-phosphate", "nucleoside 5'-phosphate dianions" ; oboInOwl:id "CHEBI:57867" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-phosphate dianion" ; rdfs:subClassOf obo:CHEBI_58945, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16701 ] . obo:CHEBI_57887 obo:IAO_0000115 "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C10H13N2" ; chebi:inchi "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1" ; chebi:inchikey "APJYDQYYACXCRM-UHFFFAOYSA-O" ; chebi:mass "161.22310" ; chebi:monoisotopicmass "161.10732" ; chebi:smiles "[NH3+]CCc1c[nH]c2ccccc12" ; oboInOwl:hasDbXref "Gmelin:533978" ; oboInOwl:hasExactSynonym "2-(1H-indol-3-yl)ethanaminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tryptamine", "tryptaminium cation", "tryptaminium(1+)" ; oboInOwl:id "CHEBI:57887" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tryptaminium" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_65296, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75771 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_16765 ] . obo:CHEBI_57925 obo:IAO_0000115 "A peptide anion obtained by deprotonation of both carboxy groups and protonation of the glutamyl amino group of glutathione; major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C10H16N3O6S" ; chebi:inchi "InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/p-1/t5-,6-/m0/s1" ; chebi:inchikey "RWSXRVCMGQZWBV-WDSKDSINSA-M" ; chebi:mass "306.310" ; chebi:monoisotopicmass "306.07653" ; chebi:smiles "[NH3+][C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)[O-])C(=O)[O-]" ; oboInOwl:hasDbXref "PMID:4200890", "PMID:4745654" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glutathionate", "glutathionate anion", "glutathionate ion", "glutathione" ; oboInOwl:id "CHEBI:57925" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glutathionate(1-)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_60334, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_23357 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16856 ] . obo:CHEBI_58001 obo:IAO_0000115 "The conjugate acid of a primary aliphatic amine." ; chebi:charge "+1" ; chebi:formula "CH5NR" ; chebi:mass "31.05710" ; chebi:monoisotopicmass "31.04220" ; chebi:smiles "[NH3+]C[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an aliphatic amine", "primary aliphatic ammonium cation", "primary aliphatic ammonium cations", "primary aliphatic ammonium ions" ; oboInOwl:id "CHEBI:58001" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "primary aliphatic ammonium ion" ; rdfs:subClassOf obo:CHEBI_65296, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17062 ] . obo:CHEBI_58025 obo:IAO_0000115 "The conjugate acid of octopamine; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C8H12NO2" ; chebi:inchi "InChI=1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2/p+1" ; chebi:inchikey "QHGUCRYDKWKLMG-UHFFFAOYSA-O" ; chebi:mass "154.18640" ; chebi:monoisotopicmass "154.08626" ; chebi:smiles "[NH3+]CC(O)c1ccc(O)cc1" ; oboInOwl:hasExactSynonym "2-hydroxy-2-(4-hydroxyphenyl)ethanaminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-hydroxy-2-(4-hydroxyphenyl)ethan-1-aminium", "4-(2-ammonio-1-hydroxyethyl)phenol", "4-(2-azaniumyl-1-hydroxyethyl)phenol", "octopamine", "octopaminium cation", "octopaminium(1+)" ; oboInOwl:id "CHEBI:58025" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "octopaminium" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17134 ] . obo:CHEBI_58104 obo:IAO_0000115 "Trianion of nucleoside triphosphate arising from deprotonation of three of the four free triphosphate OH groups." ; chebi:charge "-3" ; chebi:formula "C5H9O13P3R" ; chebi:mass "370.039" ; chebi:monoisotopicmass "369.92560" ; chebi:smiles "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)([O-])O)(=O)[O-])(=O)[O-]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NTP trianion", "NTP(3-)", "nucleoside triphosphate trianion", "ribonucleoside triphosphate trianion", "ribonucleoside triphosphate(3-)" ; oboInOwl:id "CHEBI:58104" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-triphoshate(3-)" ; rdfs:subClassOf obo:CHEBI_59724, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_61557 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17326 ] . obo:CHEBI_58165 obo:IAO_0000115 "An organophosphate oxoanion that is the conjugate base of 3',5'-cyclic AMP arising from deprotonation of the free phosphate OH group; major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C10H11N5O6P" ; chebi:inchi "InChI=1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/p-1/t4-,6-,7-,10-/m1/s1" ; chebi:inchikey "IVOMOUWHDPKRLL-KQYNXXCUSA-M" ; chebi:mass "328.19800" ; chebi:monoisotopicmass "328.04524" ; chebi:smiles "Nc1ncnc2n(cnc12)[C@@H]1O[C@@H]2COP([O-])(=O)O[C@H]2[C@H]1O" ; oboInOwl:hasDbXref "PMID:7870041", "PMID:7870042", "Reaxys:3720459" ; oboInOwl:hasExactSynonym "adenosine 3',5'-phosphate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3',5'-cyclic AMP", "3',5'-cyclic AMP anion", "adenosine 3',5'-cyclic monophosphate", "adenosine 3',5'-cyclic monophosphate anion", "adenosine 3',5'-cyclic monophosphate(1-)" ; oboInOwl:id "CHEBI:58165" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "3',5'-cyclic AMP(1-)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_58945, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_75772 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_17489 ] . obo:CHEBI_58464 obo:IAO_0000115 "The conjugate base of a nucleoside 3',5'-cyclic phosphate." ; chebi:charge "-1" ; chebi:formula "C5H6O5PR2" ; chebi:mass "177.07190" ; chebi:monoisotopicmass "176.99528" ; chebi:smiles "[O-]P1(=O)OC[C@H]2O[C@@H]([*])[C@H]([*])[C@@H]2O1" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a nucleoside 3',5'-cyclic phosphate", "nucleoside 3',5'-cyclic phosphate anions" ; oboInOwl:id "CHEBI:58464" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside 3',5'-cyclic phosphate anion" ; rdfs:subClassOf obo:CHEBI_58945, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_18375 ] . obo:CHEBI_58945 obo:IAO_0000115 "An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organophosphate oxoanions" ; oboInOwl:id "CHEBI:58945" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organophosphate oxoanion" ; rdfs:subClassOf obo:CHEBI_25696, obo:CHEBI_26079 . obo:CHEBI_58951 obo:IAO_0000115 "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6)." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a short-chain fatty acid", "short-chain fatty acid anions" ; oboInOwl:id "CHEBI:58951" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "short-chain fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_26666 ] . obo:CHEBI_58953 obo:IAO_0000115 "Any fatty acid anion in which there is no C-C unsaturation." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "saturated fatty acid anions" ; oboInOwl:id "CHEBI:58953" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "saturated fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868 . obo:CHEBI_58954 obo:IAO_0000115 "Any saturated fatty acid anion lacking a carbon side-chain." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "straight-chain saturated fatty acid anions" ; oboInOwl:id "CHEBI:58954" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "straight-chain saturated fatty acid anion" ; rdfs:subClassOf obo:CHEBI_58953, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_39418 ] . obo:CHEBI_59059 obo:IAO_0000115 "The isocyanate that is methane modified by a single isocyanato substituent." ; chebi:charge "0" ; chebi:formula "C2H3NO" ; chebi:inchi "InChI=1S/C2H3NO/c1-3-2-4/h1H3" ; chebi:inchikey "HAMGRBXTJNITHG-UHFFFAOYSA-N" ; chebi:mass "57.05130" ; chebi:monoisotopicmass "57.02146" ; chebi:smiles "CN=C=O" ; oboInOwl:hasDbXref "Beilstein:605318", "CAS:624-83-9", "DrugBank:DB04337", "Gmelin:100500", "PMID:16091349", "PMID:19494520", "PMID:24081639", "PMID:3622432", "PMID:6821040", "Reaxys:605318" ; oboInOwl:hasExactSynonym "isocyanatomethane", "methyl isocyanate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Iso-cyanatomethane", "Isocyanate de methyle", "MIC", "Methyl carbonimide", "Methyl isocyanide", "Methylcarbylamine", "isocyanatomethane" ; oboInOwl:id "CHEBI:59059" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methyl isocyanate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_53212, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50904 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_68495 ] . obo:CHEBI_59137 obo:IAO_0000115 "Cinchonan or its (8S)-epimer." ; chebi:charge "0" ; chebi:formula "C19H22N2" ; chebi:inchi "InChI=1S/C19H22N2/c1-2-14-13-21-10-8-15(14)11-17(21)12-16-7-9-20-19-6-4-3-5-18(16)19/h2-7,9,14-15,17H,1,8,10-13H2/t14-,15-,17?/m0/s1" ; chebi:inchikey "UFJOYVQIDSNLHC-GIIGEWEBSA-N" ; chebi:mass "278.39140" ; chebi:monoisotopicmass "278.17830" ; chebi:smiles "C=C[C@H]1C[N@@]2CC[C@H]1CC2Cc1ccnc2ccccc12" ; oboInOwl:hasExactSynonym "(8xi)-cinchonan" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:59137" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(8xi)-cinchonan" ; rdfs:subClassOf obo:CHEBI_26513 . obo:CHEBI_59138 obo:IAO_0000115 "The (8S)-epimer of cinchonan." ; chebi:charge "0" ; chebi:formula "C19H22N2" ; chebi:inchi "InChI=1S/C19H22N2/c1-2-14-13-21-10-8-15(14)11-17(21)12-16-7-9-20-19-6-4-3-5-18(16)19/h2-7,9,14-15,17H,1,8,10-13H2/t14-,15-,17-/m0/s1" ; chebi:inchikey "UFJOYVQIDSNLHC-ZOBUZTSGSA-N" ; chebi:mass "278.39140" ; chebi:monoisotopicmass "278.17830" ; chebi:smiles "[H][C@]1(C[C@@H]2CC[N@]1C[C@@H]2C=C)Cc1ccnc2ccccc12" ; oboInOwl:hasDbXref "Beilstein:88419" ; oboInOwl:hasExactSynonym "(8S)-cinchonan", "(8alpha)-cinchonan" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-((1S,2S,4S,5R)-5-vinyl-1-azabicyclo[2.2.2]oct-2-ylmethyl)quinoline" ; oboInOwl:id "CHEBI:59138" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(8S)-cinchonan" ; rdfs:subClassOf obo:CHEBI_59137 . obo:CHEBI_59163 obo:IAO_0000115 "A substance used as an indicator of a biological state." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "biological marker" ; oboInOwl:id "CHEBI:59163" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "biomarker" ; rdfs:subClassOf obo:CHEBI_47867 . obo:CHEBI_59202 obo:IAO_0000115 "Any fatty acid whose skeletal carbon atoms form an unbranched open chain." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "straight-chain fatty acids" ; oboInOwl:id "CHEBI:59202" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "straight-chain fatty acid" ; rdfs:subClassOf obo:CHEBI_35366, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_59203 ] . obo:CHEBI_59203 obo:IAO_0000115 "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "straight-chain FA anion", "straight-chain FA anions", "straight-chain fatty acid anions" ; oboInOwl:id "CHEBI:59203" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "straight-chain fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_59202 ] . obo:CHEBI_5924 obo:IAO_0000115 "Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.4.21.* (serine endopeptidase) inhibitors", "EC 3.4.21.* inhibitor", "EC 3.4.21.* inhibitors", "inhibitor of serine endopeptidase (EC 3.4.21.*)", "inhibitor of serine endopeptidase (EC 3.4.21.*)s", "serine endopeptidase inhibitor", "serine endopeptidase inhibitors" ; oboInOwl:id "CHEBI:5924" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.4.21.* (serine endopeptidase) inhibitor" ; rdfs:subClassOf obo:CHEBI_60258 . obo:CHEBI_59517 obo:IAO_0000115 "Any substance that inhibits the synthesis of DNA." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "DNA synthesis inhibitors" ; oboInOwl:id "CHEBI:59517" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "DNA synthesis inhibitor" ; rdfs:subClassOf obo:CHEBI_76932 . obo:CHEBI_59554 obo:IAO_0000115 "Any fatty acid with a chain length of between C6 and C12." ; chebi:charge "0" ; chebi:formula "CHO2R" ; chebi:mass "45.01740" ; chebi:monoisotopicmass "44.99765" ; chebi:smiles "OC([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "MCFA", "MCFAs", "medium-chain fatty acids" ; oboInOwl:id "CHEBI:59554" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "medium-chain fatty acid" ; rdfs:subClassOf obo:CHEBI_35366, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_59558 ] . obo:CHEBI_59558 obo:IAO_0000115 "A fatty acid anion resulting from the deprotonation of the carboxylic acid moiety of a medium-chain fatty acid." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "MCFA anion", "MCFA anions", "a medium chain fatty acid", "medium-chain FA anion", "medium-chain FA anions", "medium-chain fatty acid anions" ; oboInOwl:id "CHEBI:59558" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "medium-chain fatty acid anion" ; rdfs:subClassOf obo:CHEBI_28868, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_59554 ] . obo:CHEBI_59561 obo:IAO_0000115 "An organic anion that is the conjugate base of diamino acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "diamino acid anions" ; oboInOwl:id "CHEBI:59561" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "diamino acid anion" ; rdfs:subClassOf obo:CHEBI_25696, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_35987 ] . obo:CHEBI_59683 obo:IAO_0000115 "A drug, usually applied topically, that relieves pruritus (itching)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-itching drug", "anti-itching drugs", "antipruritic agent", "antipruritic agents", "antipruritic drugs" ; oboInOwl:id "CHEBI:59683" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antipruritic drug" ; rdfs:subClassOf obo:CHEBI_50177 . obo:CHEBI_59698 obo:IAO_0000115 "Compounds containing one or more phosphoric acid units." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:59698" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phosphoric acids" ; rdfs:subClassOf obo:CHEBI_33457 . obo:CHEBI_59724 obo:IAO_0000115 "An organophosphate anion resulting from deprotonation of at least one of the acidic hydroxy groups from the triphosphate moiety of a nucleoside triphosphate." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ribonucleoside triphosphate anion", "ribonucleoside triphosphate anions", "ribonucleoside triphosphate oxoanions" ; oboInOwl:id "CHEBI:59724" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ribonucleoside triphosphate oxoanion" ; rdfs:subClassOf obo:CHEBI_58945 . obo:CHEBI_59740 obo:IAO_0000115 "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleophile", "nucleophiles", "nucleophilic reagents" ; oboInOwl:id "CHEBI:59740" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleophilic reagent" ; rdfs:subClassOf obo:CHEBI_33893, obo:CHEBI_39144 . obo:CHEBI_59769 obo:IAO_0000115 "An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' =/= H). Mixed acetals have R'' and R''' groups which differ." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acetals" ; oboInOwl:id "CHEBI:59769" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "acetal" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_59777 obo:IAO_0000115 "An acetal of formula R2C(OR)2 (R =/= H) derived from a ketone by replacement of the oxo group by two hydrocarbyloxy groups. The class name 'ketals', once abandoned by IUPAC, has been reinstated as a subclass of acetals." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ketals" ; oboInOwl:id "CHEBI:59777" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ketal" ; rdfs:subClassOf obo:CHEBI_59769 . obo:CHEBI_59779 obo:IAO_0000115 "A ketal in the molecule of which the ketal carbon and one or both oxygen atoms thereon are members of a ring." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cyclic ketals" ; oboInOwl:id "CHEBI:59779" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cyclic ketal" ; rdfs:subClassOf obo:CHEBI_38104, obo:CHEBI_59777 . obo:CHEBI_59806 obo:IAO_0000115 "The conjugate acid of (S)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C10H15N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/p+1/t10-/m0/s1" ; chebi:inchikey "SNICXCGAKADSCV-JTQLQIEISA-O" ; chebi:mass "163.23900" ; chebi:monoisotopicmass "163.12297" ; chebi:smiles "C[NH+]1CCC[C@H]1c1cccnc1" ; oboInOwl:hasDbXref "Gmelin:329042", "MetaCyc:NICOTINE" ; oboInOwl:hasExactSynonym "(2S)-1-methyl-2-(pyridin-3-yl)pyrrolidinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(S)-nicotine", "(S)-nicotinium cation" ; oboInOwl:id "CHEBI:59806" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(S)-nicotinium(1+)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76924 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_17688 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_79008 ] . obo:CHEBI_59814 obo:IAO_0000115 "Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group." ; chebi:charge "-1" ; chebi:formula "C2H3NO2R" ; chebi:mass "73.051" ; chebi:monoisotopicmass "73.01638" ; chebi:smiles "[C@H](C(=O)[O-])(N)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-alpha-amino carboxylate" ; oboInOwl:id "CHEBI:59814" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-alpha-amino acid anion" ; rdfs:subClassOf obo:CHEBI_33558, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_15705 ] . obo:CHEBI_59869 obo:IAO_0000115 "Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "[NH3+][C@@H]([*])C([O-])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-alpha-amino acid zwitterions", "an L-alpha-amino acid" ; oboInOwl:id "CHEBI:59869" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-alpha-amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_78608, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_15705 ] . obo:CHEBI_59871 obo:IAO_0000115 "Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "[NH3+][C@H]([*])C([O-])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "D-alpha-amino acid zwitterions", "a D-alpha-amino acid" ; oboInOwl:id "CHEBI:59871" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-alpha-amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16733 ] . obo:CHEBI_59888 obo:IAO_0000115 "Zwitterionic form of gamma-aminobutyric acid having an anionic carboxy group and a protonated amino group." ; chebi:charge "0" ; chebi:formula "C4H9NO2" ; chebi:inchi "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)" ; chebi:inchikey "BTCSSZJGUNDROE-UHFFFAOYSA-N" ; chebi:mass "103.11980" ; chebi:monoisotopicmass "103.06333" ; chebi:smiles "[NH3+]CCCC([O-])=O" ; oboInOwl:hasDbXref "Gmelin:1041559" ; oboInOwl:hasExactSynonym "4-azaniumylbutanoate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-aminobutanoate", "4-ammoniobutanoate" ; oboInOwl:id "CHEBI:59888" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "gamma-aminobutyric acid zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16865 ] . obo:CHEBI_59905 obo:IAO_0000115 "An ammonium ion that is the conjugate acid of dopamine; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C8H12NO2" ; chebi:inchi "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2/p+1" ; chebi:inchikey "VYFYYTLLBUKUHU-UHFFFAOYSA-O" ; chebi:mass "154.18640" ; chebi:monoisotopicmass "154.08626" ; chebi:smiles "[NH3+]CCc1ccc(O)c(O)c1" ; oboInOwl:hasDbXref "Gmelin:328863" ; oboInOwl:hasExactSynonym "2-(3,4-dihydroxyphenyl)ethanaminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-(3,4-dihydroxyphenyl)ethan-1-aminium", "dopamine", "dopaminium cation" ; oboInOwl:id "CHEBI:59905" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dopaminium(1+)" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77746 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_18243 ] . obo:CHEBI_59999 obo:IAO_0000115 "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Chemische Substanz" ; oboInOwl:id "CHEBI:59999" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "chemical substance" ; rdfs:subClassOf obo:CHEBI_24431 . obo:CHEBI_60004 obo:IAO_0000115 "A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Mischung" ; oboInOwl:id "CHEBI:60004" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mixture" ; rdfs:subClassOf obo:CHEBI_59999 . obo:CHEBI_6015 chebi:charge "0" ; chebi:formula "C3H2ClF5O" ; chebi:inchi "InChI=1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H" ; chebi:inchikey "PIWKPBJCKXDKJR-UHFFFAOYSA-N" ; chebi:mass "184.49210" ; chebi:monoisotopicmass "183.97143" ; chebi:smiles "FC(F)OC(Cl)C(F)(F)F" ; oboInOwl:hasDbXref "CAS:26675-46-7", "DrugBank:DB00753", "Drug_Central:1493", "KEGG:C07518", "KEGG:D00545", "VSDB:1804", "Wikipedia:Isoflurane" ; oboInOwl:hasExactSynonym "2-chloro-2-difluoromethoxy-1,1,1-trifluoroethane", "Isoflurane" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-chloro-2,2,2-trifluoroethyl difluoromethyl ether", "Aerrane", "Ethane", "Forane", "Forene", "isoflurane", "isoflurano", "isofluranum" ; oboInOwl:id "CHEBI:6015" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "isoflurane" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_37143, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38870 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_39832 ] . obo:CHEBI_60240 obo:IAO_0000115 "A metal cation with a valence of two." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a divalent metal cation" ; oboInOwl:id "CHEBI:60240" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "divalent metal cation" ; rdfs:subClassOf obo:CHEBI_25213, obo:CHEBI_64641 . obo:CHEBI_60242 obo:IAO_0000115 "An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a monovalent cation" ; oboInOwl:id "CHEBI:60242" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monovalent inorganic cation" ; rdfs:subClassOf obo:CHEBI_36915 . obo:CHEBI_60258 obo:IAO_0000115 "A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*)." ; oboInOwl:hasAlternativeId "CHEBI:76763" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.4.* (hydrolase acting on peptide bond) inhibitor", "EC 3.4.* (hydrolase acting on peptide bonds) inhibitors", "EC 3.4.* (hydrolases acting on peptide bond) inhibitors", "EC 3.4.* (peptidase) inhibitor", "EC 3.4.* (peptidase) inhibitors", "EC 3.4.* inhibitor", "EC 3.4.* inhibitors", "inhibitor of hydrolases acting on peptide bond (EC 3.4.*)", "inhibitors of hydrolases acting on peptide bond (EC 3.4.*)", "peptidase inhibitors", "protease inhibitor", "protease inhibitors" ; oboInOwl:id "CHEBI:60258" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.4.* (hydrolases acting on peptide bond) inhibitor" ; rdfs:subClassOf obo:CHEBI_76759 . obo:CHEBI_60330 obo:IAO_0000115 "The oxime resulting from the formal condensation of 2-methyl-2-(methylsulfanyl)propanal with hydroxylamine. Addition of the oxime group to methyl isocyanate forms the final step in the synthesis of the systemic insecticide aldicarb." ; chebi:charge "0" ; chebi:formula "C5H11NOS" ; chebi:inchi "InChI=1S/C5H11NOS/c1-5(2,8-3)4-6-7/h4,7H,1-3H3" ; chebi:inchikey "ZFGMCJAXIZTVJA-UHFFFAOYSA-N" ; chebi:mass "133.21200" ; chebi:monoisotopicmass "133.05614" ; chebi:smiles "[H]C(=NO)C(C)(C)SC" ; oboInOwl:hasDbXref "Beilstein:2038299", "CAS:1646-75-9", "Patent:US3217037", "Reaxys:2038299" ; oboInOwl:hasExactSynonym "2-methyl-2-(methylsulfanyl)propanal oxime", "N-hydroxy-2-methyl-2-(methylsulfanyl)propan-1-imine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-(methylthio)-2-methylpropionaldehyde oxime", "2-(methylthio)isobutyraldehyde oxime", "2-methyl-2-(methylsulfanyl)propanaldoxime", "2-methyl-2-(methylthio)propanal oxime", "2-methyl-2-(methylthio)propionaldehyde oxime", "2-methyl-2-(methylthio)propionaldoxime", "ADO", "Temik oxime", "aldicarb oxime" ; oboInOwl:id "CHEBI:60330" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "2-methyl-2-(methylsulfanyl)propanal oxime" ; rdfs:subClassOf obo:CHEBI_82744, obo:CHEBI_86315 . obo:CHEBI_60334 obo:IAO_0000115 "An anion formed by deprotonation of at least one peptide carboxy group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "peptide anions" ; oboInOwl:id "CHEBI:60334" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "peptide anion" ; rdfs:subClassOf obo:CHEBI_25696 . obo:CHEBI_60466 obo:IAO_0000115 "Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged." ; chebi:charge "0" ; chebi:formula "C2H4NO2R(C2H2NOR)n" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a peptide", "peptide zwitterions" ; oboInOwl:id "CHEBI:60466" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "peptide zwitterion" ; rdfs:subClassOf obo:CHEBI_27369, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_16670 ] . obo:CHEBI_60643 obo:IAO_0000115 "Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs." ; oboInOwl:hasAlternativeId "CHEBI:60797" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "N-methyl-D-aspartate receptor antagonist", "N-methyl-D-aspartate receptor antagonists", "NMDA receptor antagonists", "NMDAR antagonist", "NMDAR antagonists" ; oboInOwl:id "CHEBI:60643" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "NMDA receptor antagonist" ; rdfs:subClassOf obo:CHEBI_60798 . obo:CHEBI_6078 obo:IAO_0000115 "A mixture consisting of >= 90% 22,23-dihydroavermectin B1a (R = Me) and <= 10% 22,23-dihydroavermectin B1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice." ; chebi:charge "0" ; chebi:formula "C47H71O14R", "C48H74O14.C47H72O14" ; chebi:mass "860.060" ; chebi:monoisotopicmass "859.48438" ; chebi:smiles "[H][C@@]12C\\C=C(C)\\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\\C=C\\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(CC[C@H](C)[C@]([H])(O1)[C@@H](C)C[*])O2)[C@]34O" ; oboInOwl:hasDbXref "CAS:70288-86-7", "Chemspider:7988461", "DrugBank:DB00602", "KEGG:D00804", "PMID:15078277", "PMID:18718154", "PMID:21824728", "PMID:21831526", "PMID:22039784", "PMID:22039801", "PMID:22047763", "Patent:US4199569", "Pesticides:ivermectin", "VSDB:1455", "Wikipedia:Ivermectin" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Ivermax", "Ivomec", "Mectizan", "Noromectin", "Privermectin", "Sklice", "Stromectol", "Vetrimec", "Zimecterin", "ivermectin", "ivermectine", "ivermectino", "ivermectinum" ; oboInOwl:id "CHEBI:6078" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ivermectin" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_60004, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_63941 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_63943 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24852 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35444 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35820 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_73333 ] . obo:CHEBI_60798 obo:IAO_0000115 "Any substance which inhibits the action of receptors for excitatory amino acids." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EAA receptor antagonist", "EAA receptor antagonists", "excitatory amino acid antagonists", "excitatory amino acid receptor antagonist", "excitatory amino acid receptor antagonists" ; oboInOwl:id "CHEBI:60798" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "excitatory amino acid antagonist" ; rdfs:subClassOf obo:CHEBI_48706 . obo:CHEBI_60809 obo:IAO_0000115 "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adjuvants" ; oboInOwl:id "CHEBI:60809" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adjuvant" ; rdfs:subClassOf obo:CHEBI_52217 . obo:CHEBI_60832 obo:IAO_0000115 "Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tubulin modulators" ; oboInOwl:id "CHEBI:60832" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tubulin modulator" ; rdfs:subClassOf obo:CHEBI_52210 . obo:CHEBI_60895 obo:IAO_0000115 "Any alpha-amino acid anion in which the parent amino acid has D-configuration." ; chebi:charge "-1" ; chebi:formula "C2H3NO2R" ; chebi:mass "73.051" ; chebi:monoisotopicmass "73.01638" ; chebi:smiles "[C@@H](C(=O)[O-])(N)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "D-alpha-amino acid anions", "D-alpha-amino carboxylate" ; oboInOwl:id "CHEBI:60895" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "D-alpha-amino acid anion" ; rdfs:subClassOf obo:CHEBI_33558, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16733 ] . obo:CHEBI_60911 obo:IAO_0000115 "A racemate is an equimolar mixture of a pair of enantiomers." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "melange racemique", "racemates", "racemic mixture" ; oboInOwl:id "CHEBI:60911" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "racemate" ; rdfs:subClassOf obo:CHEBI_60004 . obo:CHEBI_61115 obo:IAO_0000115 "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98)." ; oboInOwl:hasDbXref "Wikipedia:Histone_deacetylase_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.5.1.98 (histone deacetylase) inhibitors", "EC 3.5.1.98 inhibitor", "EC 3.5.1.98 inhibitors", "HDAC inhibitor", "HDAC inhibitors", "HDACi", "HDACis", "HDI", "HDIs", "histone amidohydrolase inhibitor", "histone amidohydrolase inhibitors", "histone deacetylase (EC 3.5.1.98) inhibitor", "histone deacetylase (EC 3.5.1.98) inhibitors", "histone deacetylase inhibitor", "histone deacetylase inhibitors" ; oboInOwl:id "CHEBI:61115" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.5.1.98 (histone deacetylase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76807 . obo:CHEBI_61120 obo:IAO_0000115 "Any compound that has a nucleobase as a part." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "nucleobase-containing compound", "nucleobase-containing compounds", "nucleobase-containing molecular entities" ; oboInOwl:id "CHEBI:61120" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleobase-containing molecular entity" ; rdfs:subClassOf obo:CHEBI_33833, obo:CHEBI_51143, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_18282 ] . obo:CHEBI_61293 obo:IAO_0000115 "A nucleotide having adenine as the base." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenine nucleotide" ; oboInOwl:id "CHEBI:61293" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adenyl nucleotide" ; rdfs:subClassOf obo:CHEBI_26395 . obo:CHEBI_61296 obo:IAO_0000115 "A purine riboncleotide where adenine is the purine." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenine ribonucleotide" ; oboInOwl:id "CHEBI:61296" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adenyl ribonucleotide" ; rdfs:subClassOf obo:CHEBI_26400, obo:CHEBI_61293 . obo:CHEBI_61557 obo:IAO_0000115 "A ribonucleoside triphosphate oxoanion arising from global deprotonation of the triphosphate groups of any nucleoside triphosphate; major species at pH 7.3." ; chebi:charge "-4" ; chebi:formula "C5H8O13P3R" ; chebi:mass "369.031" ; chebi:monoisotopicmass "368.91778" ; chebi:smiles "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)([O-])[O-])(=O)[O-])(=O)[O-]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "NTP tetraanion", "NTP(4-)", "a ribonucleoside 5'-triphosphate", "nucleoside 5'-triphosphate tetraanion", "nucleoside triphosphate(4-)" ; oboInOwl:id "CHEBI:61557" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleoside 5'-triphoshate(4-)" ; rdfs:subClassOf obo:CHEBI_59724, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_58104 ] . obo:CHEBI_61692 obo:IAO_0000115 "An organic heterotricyclic compound with a skeleton derived from a pyridine ring fused to an isoquinoline." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pyridoisoquinolines" ; oboInOwl:id "CHEBI:61692" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pyridoisoquinoline" ; rdfs:subClassOf obo:CHEBI_26979 . obo:CHEBI_61697 obo:IAO_0000115 "Any organic molecular entity derived from a fatty acid." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "FA derivative", "FA derivatives", "fatty acid derivatives" ; oboInOwl:id "CHEBI:61697" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fatty acid derivative" ; rdfs:subClassOf obo:CHEBI_18059, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_35366 ] . obo:CHEBI_61951 obo:IAO_0000115 "Any substance that interacts with tubulin to inhibit polymerisation of microtubules." ; oboInOwl:hasDbXref "PMID:17099073" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "microtubule destabilising agent", "microtubule destabilising agents", "microtubule destabilising role", "microtubule destabilizing role", "microtubule-destabilising agents", "microtubule-destabilizing agent", "microtubule-destabilizing agents" ; oboInOwl:id "CHEBI:61951" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "microtubule-destabilising agent" ; rdfs:subClassOf obo:CHEBI_60832, obo:CHEBI_64911 . obo:CHEBI_62031 obo:IAO_0000115 "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "C(C([O-])=O)(*)[NH3+]" ; oboInOwl:hasDbXref "MetaCyc:Polar-amino-acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a polar amino acid" ; oboInOwl:id "CHEBI:62031" ; oboInOwl:inSubset chebi2:_STAR ; a owl:Class ; rdfs:label "polar amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_26167 ] . obo:CHEBI_62081 obo:IAO_0000115 "An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens." ; chebi:charge "-1" ; chebi:formula "CH2O3SR" ; chebi:mass "94.09000" ; chebi:monoisotopicmass "93.97246" ; chebi:smiles "[H]C([H])([*])S([O-])(=O)=O" ; oboInOwl:hasDbXref "KEGG:C15521", "MetaCyc:Alkanesulfonates" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1,1-di-unsubstituted alkanesulfonate", "1,1-di-unsubstituted alkanesulfonates", "1,1-diunsubstituted alkanesulfonates" ; oboInOwl:id "CHEBI:62081" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "1,1-diunsubstituted alkanesulfonate" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_134249, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ] . obo:CHEBI_62488 obo:IAO_0000115 "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "signal molecule", "signal molecules", "signaling molecule", "signaling molecules", "signalling molecules" ; oboInOwl:id "CHEBI:62488" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "signalling molecule" ; rdfs:subClassOf obo:CHEBI_33280 . obo:CHEBI_62643 obo:IAO_0000115 "Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1-), phosphatidate(2-), phosphatidylglycerol(1-)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anionic phospholipids", "phospholipid anion", "phospholipid anions" ; oboInOwl:id "CHEBI:62643" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anionic phospholipid" ; rdfs:subClassOf obo:CHEBI_58945, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_16247 ] . obo:CHEBI_63046 obo:IAO_0000115 "The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "emulgent", "emulgents", "emulsifiers" ; oboInOwl:id "CHEBI:63046" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "emulsifier" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_63161 obo:IAO_0000115 "A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "glycosyl compounds" ; oboInOwl:id "CHEBI:63161" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "glycosyl compound" ; rdfs:subClassOf obo:CHEBI_63299 . obo:CHEBI_63248 obo:IAO_0000115 "A substance that removes electrons from another reactant in a redox reaction." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "oxidant", "oxidants", "oxidiser", "oxidisers", "oxidising agents", "oxidizer", "oxidizers", "oxidizing agent", "oxidizing agents" ; oboInOwl:id "CHEBI:63248" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "oxidising agent" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_63299 obo:IAO_0000115 "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrate derivatives", "derivatised carbohydrate", "derivatised carbohydrates", "derivatized carbohydrate", "derivatized carbohydrates" ; oboInOwl:id "CHEBI:63299" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbohydrate derivative" ; rdfs:subClassOf obo:CHEBI_78616, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_16646 ] . obo:CHEBI_63332 obo:IAO_0000115 "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1)." ; oboInOwl:hasDbXref "Wikipedia:Alkaline_phosphatase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.3.1 (alkaline phosphatase) inhibitors", "EC 3.1.3.1 inhibitor", "EC 3.1.3.1 inhibitors", "alkaline phenyl phosphatase inhibitor", "alkaline phenyl phosphatase inhibitors", "alkaline phosphatase (EC 3.1.3.1) inhibitor", "alkaline phosphatase (EC 3.1.3.1) inhibitors", "alkaline phosphatase inhibitor", "alkaline phosphatase inhibitors", "alkaline phosphohydrolase inhibitor", "alkaline phosphohydrolase inhibitors", "alkaline phosphomonoesterase inhibitor", "alkaline phosphomonoesterase inhibitors", "glycerophosphatase inhibitor", "glycerophosphatase inhibitors", "orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitor", "orthophosphoric-monoester phosphohydrolase (alkaline optimum) inhibitors", "phosphate-monoester phosphohydrolase (alkaline optimum) inhibitor", "phosphate-monoester phosphohydrolase (alkaline optimum) inhibitors", "phosphomonoesterase inhibitor", "phosphomonoesterase inhibitors" ; oboInOwl:id "CHEBI:63332" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.1.3.1 (alkaline phosphatase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76775 . obo:CHEBI_63367 obo:IAO_0000115 "A carbohydrate derivative that is formally obtained from a monosaccharide." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monosaccharide derivatives" ; oboInOwl:id "CHEBI:63367" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monosaccharide derivative" ; rdfs:subClassOf obo:CHEBI_63299, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_35381 ] . obo:CHEBI_63409 obo:IAO_0000115 "A monosaccharide derivative that is formally obtained from a pentose." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pentose derivatives" ; oboInOwl:id "CHEBI:63409" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pentose derivative" ; rdfs:subClassOf obo:CHEBI_63367, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_25901 ] . obo:CHEBI_63470 obo:IAO_0000115 "A sulfur-containing amino acid whose alpha-carboxylic acid group is ionized (not protonated)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "sulfur-containing amino-acid anions" ; oboInOwl:id "CHEBI:63470" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "sulfur-containing amino-acid anion" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_26834 ] . obo:CHEBI_63490 obo:IAO_0000115 "A substance capable of undergoing rapid and highly exothermic decomposition." ; oboInOwl:hasDbXref "Wikipedia:Explosive_material" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "explosive compound", "explosive compounds", "explosive material", "explosives", "explosives chemical", "explosives chemicals" ; oboInOwl:id "CHEBI:63490" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "explosive" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_63510 obo:IAO_0000115 "An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of Na(+)/K(+)-transporting ATPase (EC 3.6.3.9)." ; oboInOwl:hasDbXref "Wikipedia:Sodium-potassium_ATPase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitors", "EC 3.6.3.9 inhibitor", "EC 3.6.3.9 inhibitors", "Na(+)/K(+)-ATPase inhibitor", "Na(+)/K(+)-ATPase inhibitors", "Na(+)/K(+)-pump inhibitor", "Na(+)/K(+)-pump inhibitors", "Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitor", "Na(+)/K(+)-transporting ATPase (EC 3.6.3.9) inhibitors", "Na(+)/K(+)-transporting ATPase inhibitor", "Na(+)/K(+)-transporting ATPase inhibitors", "sodium pump inhibitor", "sodium pump inhibitors", "sodium-potassium adenosine triphosphatase inhibitor", "sodium-potassium adenosine triphosphatase inhibitors", "sodium-potassium pump inhibitor", "sodium-potassium pump inhibitors" ; oboInOwl:id "CHEBI:63510" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76895 . obo:CHEBI_63534 obo:IAO_0000115 "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes." ; oboInOwl:hasDbXref "PMID:21822758", "PMID:21993877", "PMID:22005599", "PMID:22082101", "PMID:22153577", "PMID:22213370", "PMID:22218931", "PMID:22342987", "PMID:22371656" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monoamines", "naturally occurring monoamine", "naturally occurring monoamines" ; oboInOwl:id "CHEBI:63534" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monoamine" ; rdfs:subClassOf obo:CHEBI_64365 . obo:CHEBI_63726 obo:IAO_0000115 "Any compound that can be used for the treatment of neurodegenerative disorders." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "neuroprotectant", "neuroprotectants", "neuroprotective agents" ; oboInOwl:id "CHEBI:63726" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "neuroprotective agent" ; rdfs:subClassOf obo:CHEBI_50267 . obo:CHEBI_63941 obo:IAO_0000115 "A macrocyclic lactone that is avermectin B1a in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the major component of ivermectin." ; chebi:charge "0" ; chebi:formula "C48H74O14" ; chebi:inchi "InChI=1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1" ; chebi:inchikey "AZSNMRSAGSSBNP-XPNPUAGNSA-N" ; chebi:mass "875.09280" ; chebi:monoisotopicmass "874.50786" ; chebi:smiles "[H][C@@]12C\\C=C(C)\\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\\C=C\\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(CC[C@H](C)[C@]([H])(O1)[C@@H](C)CC)O2)[C@]34O" ; oboInOwl:hasDbXref "CAS:71827-03-7", "PDBeChem:IVM", "PMID:2411323", "PMID:6125361", "PMID:6148214", "PMID:6547280", "Reaxys:4643153", "VSDB:1455" ; oboInOwl:hasExactSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-O-demethyl-22,23-dihydroavermectin A1a", "H2B1a", "avermectin H2B1a", "dihydroavermectin B1a", "ivermectin B1a" ; oboInOwl:id "CHEBI:63941" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "22,23-dihydroavermectin B1a" ; rdfs:subClassOf obo:CHEBI_63944, obo:CHEBI_72600, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_29534 ] . obo:CHEBI_63943 obo:IAO_0000115 "A macrocyclic lactone that is avermectin B1b in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the minor component of ivermectin." ; chebi:charge "0" ; chebi:formula "C47H72O14" ; chebi:inchi "InChI=1S/C47H72O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,18,24-25,27,29-30,32-44,48-49,51H,15-17,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m0/s1" ; chebi:inchikey "VARHUCVRRNANBD-PVVXTEPVSA-N" ; chebi:mass "861.06620" ; chebi:monoisotopicmass "860.49221" ; chebi:smiles "[H][C@@]12C\\C=C(C)\\[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)\\C=C\\C=C3/CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O[C@@H](C1)C[C@]1(CC[C@H](C)[C@]([H])(O1)C(C)C)O2)[C@]34O" ; oboInOwl:hasDbXref "CAS:70209-81-3", "PMID:6125361", "PMID:6148214", "PMID:6895285", "PMID:6896121", "Reaxys:8183665" ; oboInOwl:hasExactSynonym "(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-6'-(propan-2-yl)-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H2B1b", "avermectin H2B1b", "dihydroavermectin B1b", "ivermectin B1b", "ivermectin component b1b" ; oboInOwl:id "CHEBI:63943" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "22,23-dihydroavermectin B1b" ; rdfs:subClassOf obo:CHEBI_63944, obo:CHEBI_72600, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_29537 ] . obo:CHEBI_63944 obo:IAO_0000115 "Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule." ; oboInOwl:hasAlternativeId "CHEBI:50333" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "macrocyclic lactones" ; oboInOwl:id "CHEBI:63944" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "macrocyclic lactone" ; rdfs:subClassOf obo:CHEBI_25000, obo:CHEBI_51026 . obo:CHEBI_64018 obo:IAO_0000115 "An agonist that selectively binds to and activates a protein kinase C receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "protein kinase C agonists" ; oboInOwl:id "CHEBI:64018" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "protein kinase C agonist" ; rdfs:subClassOf obo:CHEBI_64106 . obo:CHEBI_64047 obo:IAO_0000115 "Any substance which is added to food to preserve or enhance its flavour and/or appearance." ; oboInOwl:hasDbXref "Wikipedia:Food_additive" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food additives" ; oboInOwl:id "CHEBI:64047" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "food additive" ; rdfs:subClassOf obo:CHEBI_33232, obo:CHEBI_78295 . obo:CHEBI_64049 obo:IAO_0000115 "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents." ; oboInOwl:hasDbXref "Wikipedia:Acidity_regulator" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "acidity regulator", "acidity regulators", "food acidity regulators", "pH control agent", "pH control agents" ; oboInOwl:id "CHEBI:64049" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "food acidity regulator" ; rdfs:subClassOf obo:CHEBI_64047 . obo:CHEBI_64106 obo:IAO_0000115 "An agonist that selectively binds to and activates a protein kinase receptor." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "protein kinase agonists" ; oboInOwl:id "CHEBI:64106" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "protein kinase agonist" ; rdfs:subClassOf obo:CHEBI_48705 . obo:CHEBI_64203 obo:IAO_0000115 "A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively)." ; chebi:charge "0" ; chebi:formula "C20H24N2S2" ; chebi:inchi "InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3" ; chebi:inchikey "RLJFTICUTYVZDG-UHFFFAOYSA-N" ; chebi:mass "356.54800" ; chebi:monoisotopicmass "356.13809" ; chebi:smiles "CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1" ; oboInOwl:hasDbXref "CAS:20229-30-5", "HMDB:HMDB0254534", "LINCS:LSM-4320", "PMID:18033297", "PMID:18996971", "PMID:19837141", "PMID:19995401", "PMID:20171242", "PMID:20233210", "PMID:20331882", "PMID:20547148", "PMID:21062995", "PMID:21403818", "PMID:21514998", "PMID:21964383", "Patent:NL6608618", "Patent:US3379729", "Patent:US4444778", "Patent:US6331536", "Reaxys:626221", "Wikipedia:Metitepine" ; oboInOwl:hasExactSynonym "1-methyl-4-[8-(methylsulfanyl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+-)-1-(10,11-Dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methylpiperazine", "(+-)-10-(4-Methylpiperazinyl)-8-(methylthio)-10,11-dihydrodibenzo(b,f)thiepin", "(+-)-8-Methylthio-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin", "1-(10,11-Dihydro-8-(methylthio)dibenzo(b,f)thiepin-10-yl)-4-methylpiperazine", "1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazine", "Methiothepine", "metitepina", "metitepine", "metitepinum" ; oboInOwl:id "CHEBI:64203" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methiothepin" ; rdfs:subClassOf obo:CHEBI_35683, obo:CHEBI_38924, obo:CHEBI_46845, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35476 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48279 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_48561 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_64204 ] . obo:CHEBI_64204 obo:IAO_0000115 "A doubly-charged organic cation arising from protonation of the two tertiary amino functions of methiothepin." ; chebi:charge "+2" ; chebi:formula "C20H26N2S2" ; chebi:inchi "InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3/p+2" ; chebi:inchikey "RLJFTICUTYVZDG-UHFFFAOYSA-P" ; chebi:mass "358.56400" ; chebi:monoisotopicmass "358.15264" ; chebi:smiles "CSc1ccc2Sc3ccccc3CC([NH+]3CC[NH+](C)CC3)c2c1" ; oboInOwl:hasExactSynonym "1-methyl-4-[8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazinediium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "methiothepin cation" ; oboInOwl:id "CHEBI:64204" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methiothepin(2+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_64203 ] . obo:CHEBI_64228 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 11-methyldodec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C36H58N4O16" ; chebi:inchi "InChI=1S/C36H58N4O16/c1-17(2)11-9-7-5-4-6-8-10-12-22(44)38-25-29(49)26(46)20(53-35(25)56-34-24(37-18(3)42)28(48)27(47)21(16-41)54-34)15-19(43)32-30(50)31(51)33(55-32)40-14-13-23(45)39-36(40)52/h10,12-14,17,19-21,24-35,41,43,46-51H,4-9,11,15-16H2,1-3H3,(H,37,42)(H,38,44)(H,39,45,52)/b12-10+/t19-,20-,21-,24-,25-,26+,27-,28-,29-,30+,31-,32-,33-,34-,35+/m1/s1" ; chebi:inchikey "FIIRBPHYBLFBSD-MZPZZZQLSA-N" ; chebi:mass "802.86290" ; chebi:monoisotopicmass "802.38478" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-11-methyldodec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(11-methyldodec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin I" ; oboInOwl:id "CHEBI:64228" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin A0" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64237 obo:IAO_0000115 "An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitors", "EC 2.7.8.15 inhibitor", "EC 2.7.8.15 inhibitors", "GlcNAc-1-P transferase inhibitor", "GlcNAc-1-P transferase inhibitors", "N-acetylglucosamine phosphotransferase inhibitor", "N-acetylglucosamine transferase inhibitors", "N-acetylglucosamine-1-phosphate transferase inhibitor", "N-acetylglucosamine-1-phosphate transferase inhibitors", "UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitor", "UDP-D-N-acetylglucosamine N-acetylglucosamine 1-phosphate transferase inhibitors", "UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitor", "UDP-GlcNAc:dolichyl-phosphate GlcNAc-1-phosphate transferase inhibitors", "UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitor", "UDP-N-acetyl-D-glucosamine:dolichol phosphate N-acetyl-D-glucosamine-1-phosphate transferase inhibitors", "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitor", "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase inhibitors", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitor", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) inhibitors", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitor", "UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase inhibitors", "UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitor", "UDP-acetylglucosamine--dolichol phosphate acetylglucosamine phosphotransferase inhibitors", "UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitor", "UDP-acetylglucosamine--dolichol phosphate acetylglucosamine-1-phosphotransferase inhibitors", "chitobiosylpyrophosphoryldolichol synthase inhibitor", "chitobiosylpyrophosphoryldolichol synthase inhibitors", "dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitor", "dolichol phosphate N-acetylglucosamine-1-phosphotransferase inhibitors", "uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitor", "uridine diphosphoacetylglucosamine--dolichyl phosphate acetylglucosamine-1-phosphotransferase inhibitors" ; oboInOwl:id "CHEBI:64237" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76816 . obo:CHEBI_64245 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 12-methyltridec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C37H60N4O16" ; chebi:inchi "InChI=1S/C37H60N4O16/c1-18(2)12-10-8-6-4-5-7-9-11-13-23(45)39-26-30(50)27(47)21(54-36(26)57-35-25(38-19(3)43)29(49)28(48)22(17-42)55-35)16-20(44)33-31(51)32(52)34(56-33)41-15-14-24(46)40-37(41)53/h11,13-15,18,20-22,25-36,42,44,47-52H,4-10,12,16-17H2,1-3H3,(H,38,43)(H,39,45)(H,40,46,53)/b13-11+/t20-,21-,22-,25-,26-,27+,28-,29-,30-,31+,32-,33-,34-,35-,36+/m1/s1" ; chebi:inchikey "YJQCOFNZVFGCAF-LLXUUZRASA-N" ; chebi:mass "816.88950" ; chebi:monoisotopicmass "816.40043" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468", "Reaxys:8183793" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-12-methyltridec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(12-methyltridec-2-enamido)-beta-D-galactopyranos-6-yl]uridine", "tunicamycin A1" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin C", "tunicamycin II" ; oboInOwl:id "CHEBI:64245" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin A1" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64246 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a tetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C37H60N4O16" ; chebi:inchi "InChI=1S/C37H60N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-23(45)39-26-30(50)27(47)21(54-36(26)57-35-25(38-19(2)43)29(49)28(48)22(18-42)55-35)17-20(44)33-31(51)32(52)34(56-33)41-16-15-24(46)40-37(41)53/h13-16,20-22,25-36,42,44,47-52H,3-12,17-18H2,1-2H3,(H,38,43)(H,39,45)(H,40,46,53)/b14-13+/t20-,21-,22-,25-,26-,27+,28-,29-,30-,31+,32-,33-,34-,35-,36+/m1/s1" ; chebi:inchikey "MMDMXWRRAOLMDC-ZNZAGFTISA-N" ; chebi:mass "816.88950" ; chebi:monoisotopicmass "816.40043" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]tetradec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(tetradec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin III" ; oboInOwl:id "CHEBI:64246" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin A2" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64248 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a pentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C38H62N4O16" ; chebi:inchi "InChI=1S/C38H62N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(2)44)30(50)29(49)23(19-43)56-36)18-21(45)34-32(52)33(53)35(57-34)42-17-16-25(47)41-38(42)54/h14-17,21-23,26-37,43,45,48-53H,3-13,18-19H2,1-2H3,(H,39,44)(H,40,46)(H,41,47,54)/b15-14+/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1" ; chebi:inchikey "QYVMTFXNKNWWFX-YGTZKZKGSA-N" ; chebi:mass "830.91610" ; chebi:monoisotopicmass "830.41608" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]pentadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(pentadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin IV" ; oboInOwl:id "CHEBI:64248" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin B1" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64250 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 13-methyltetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C38H62N4O16" ; chebi:inchi "InChI=1S/C38H62N4O16/c1-19(2)13-11-9-7-5-4-6-8-10-12-14-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(3)44)30(50)29(49)23(18-43)56-36)17-21(45)34-32(52)33(53)35(57-34)42-16-15-25(47)41-38(42)54/h12,14-16,19,21-23,26-37,43,45,48-53H,4-11,13,17-18H2,1-3H3,(H,39,44)(H,40,46)(H,41,47,54)/b14-12+/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1" ; chebi:inchikey "MEYZYGMYMLNUHJ-DIRMKAHISA-N" ; chebi:mass "830.91610" ; chebi:monoisotopicmass "830.41608" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468", "Reaxys:5711197" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-13-methyltetradec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(13-methyltetradec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin A", "tunicamycin V" ; oboInOwl:id "CHEBI:64250" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin B2" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64255 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 13-methyltetradecanoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C38H64N4O16" ; chebi:inchi "InChI=1S/C38H64N4O16/c1-19(2)13-11-9-7-5-4-6-8-10-12-14-24(46)40-27-31(51)28(48)22(55-37(27)58-36-26(39-20(3)44)30(50)29(49)23(18-43)56-36)17-21(45)34-32(52)33(53)35(57-34)42-16-15-25(47)41-38(42)54/h15-16,19,21-23,26-37,43,45,48-53H,4-14,17-18H2,1-3H3,(H,39,44)(H,40,46)(H,41,47,54)/t21-,22-,23-,26-,27-,28+,29-,30-,31-,32+,33-,34-,35-,36-,37+/m1/s1" ; chebi:inchikey "XAFNQFHOQPRGAK-KTVOANSYSA-N" ; chebi:mass "832.93200" ; chebi:monoisotopicmass "832.43173" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)CCCCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-13-methyltetradecanamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(13-methyltetradecanamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "tunicamycin VI" ; oboInOwl:id "CHEBI:64255" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin B3" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64256 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 14-methylpentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C39H64N4O16" ; chebi:inchi "InChI=1S/C39H64N4O16/c1-20(2)14-12-10-8-6-4-5-7-9-11-13-15-25(47)41-28-32(52)29(49)23(56-38(28)59-37-27(40-21(3)45)31(51)30(50)24(19-44)57-37)18-22(46)35-33(53)34(54)36(58-35)43-17-16-26(48)42-39(43)55/h13,15-17,20,22-24,27-38,44,46,49-54H,4-12,14,18-19H2,1-3H3,(H,40,45)(H,41,47)(H,42,48,55)/b15-13+/t22-,23-,24-,27-,28-,29+,30-,31-,32-,33+,34-,35-,36-,37-,38+/m1/s1" ; chebi:inchikey "ZOCXUHJGZXXIGQ-NPXWYGMKSA-N" ; chebi:mass "844.94270" ; chebi:monoisotopicmass "844.43173" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "CAS:66081-36-5", "Chemspider:27471426", "MetaCyc:CPD-19373", "PMID:29844049", "PMID:29973921", "PMID:30445836", "PMID:33636028", "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-14-methylpentadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(14-methylpentadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "corynetoxin U-16I", "tunicamycin B", "tunicamycin VII" ; oboInOwl:id "CHEBI:64256" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin C1" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76507 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76969 ] . obo:CHEBI_64257 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a hexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C39H64N4O16" ; chebi:inchi "InChI=1S/C39H64N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(47)41-28-32(52)29(49)23(56-38(28)59-37-27(40-21(2)45)31(51)30(50)24(20-44)57-37)19-22(46)35-33(53)34(54)36(58-35)43-18-17-26(48)42-39(43)55/h15-18,22-24,27-38,44,46,49-54H,3-14,19-20H2,1-2H3,(H,40,45)(H,41,47)(H,42,48,55)/b16-15+/t22-,23-,24-,27-,28-,29+,30-,31-,32-,33+,34-,35-,36-,37-,38+/m1/s1" ; chebi:inchikey "NKDRZEIENXWUCE-VDIUWDQWSA-N" ; chebi:mass "844.94270" ; chebi:monoisotopicmass "844.43173" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]hexadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(hexadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:64257" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin C2" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64271 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a heptadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C40H66N4O16" ; chebi:inchi "InChI=1S/C40H66N4O16/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-26(48)42-29-33(53)30(50)24(57-39(29)60-38-28(41-22(2)46)32(52)31(51)25(21-45)58-38)20-23(47)36-34(54)35(55)37(59-36)44-19-18-27(49)43-40(44)56/h16-19,23-25,28-39,45,47,50-55H,3-15,20-21H2,1-2H3,(H,41,46)(H,42,48)(H,43,49,56)/b17-16+/t23-,24-,25-,28-,29-,30+,31-,32-,33-,34+,35-,36-,37-,38-,39+/m1/s1" ; chebi:inchikey "DYGXSHBNTGWENQ-YTXMDVFISA-N" ; chebi:mass "858.96920" ; chebi:monoisotopicmass "858.44738" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCCCCC)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]heptadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(heptadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:64271" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin D1" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_64272 obo:IAO_0000115 "A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 15-methylhexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety." ; chebi:charge "0" ; chebi:formula "C40H66N4O16" ; chebi:inchi "InChI=1S/C40H66N4O16/c1-21(2)15-13-11-9-7-5-4-6-8-10-12-14-16-26(48)42-29-33(53)30(50)24(57-39(29)60-38-28(41-22(3)46)32(52)31(51)25(20-45)58-38)19-23(47)36-34(54)35(55)37(59-36)44-18-17-27(49)43-40(44)56/h14,16-18,21,23-25,28-39,45,47,50-55H,4-13,15,19-20H2,1-3H3,(H,41,46)(H,42,48)(H,43,49,56)/b16-14+/t23-,24-,25-,28-,29-,30+,31-,32-,33-,34+,35-,36-,37-,38-,39+/m1/s1" ; chebi:inchikey "XCEPHNBEHQJSSB-LGJGITPNSA-N" ; chebi:mass "858.96920" ; chebi:monoisotopicmass "858.44738" ; chebi:smiles "[H][C@@](O)(C[C@H]1O[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC(=O)\\C=C\\CCCCCCCCCCCC(C)C)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O" ; oboInOwl:hasDbXref "PMID:7061468" ; oboInOwl:hasExactSynonym "(2E)-N-[(2S,3R,4R,5R,6R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-{(2R)-2-[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-2-hydroxyethyl}-4,5-dihydroxytetrahydro-2H-pyran-3-yl]-15-methylhexadec-2-enamide", "(5'R)-5'-[2-acetamido-2-deoxy-alpha-D-glucopyranosyl-(1<->1)-2,6-dideoxy-2-(15-methylhexadec-2-enamido)-beta-D-galactopyranos-6-yl]uridine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:64272" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "tunicamycin D2" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33838, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33281 ] . obo:CHEBI_6432 obo:IAO_0000115 "A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has S configuration. It is used (generally as the monohydrochloride salt) to treat parasitic worm infections in pigs, sheep and cattle and was formerly used in humans as an adjuvant to chemotherapy for the treatment of various cancers. It is also widely used as an adulterant to coccaine." ; chebi:charge "0" ; chebi:formula "C11H12N2S" ; chebi:inchi "InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m1/s1" ; chebi:inchikey "HLFSDGLLUJUHTE-SNVBAGLBSA-N" ; chebi:mass "204.29100" ; chebi:monoisotopicmass "204.07212" ; chebi:smiles "C1CN2C[C@@H](N=C2S1)c1ccccc1" ; oboInOwl:hasDbXref "CAS:14769-73-4", "DrugBank:DB00848", "Drug_Central:1561", "HMDB:HMDB0014986", "KEGG:C07070", "KEGG:D08114", "LINCS:LSM-6655", "PMID:10701095", "PMID:12232676", "PMID:12749943", "PMID:15109274", "PMID:1618599", "PMID:17608969", "PMID:189006", "PMID:2050823", "PMID:22337783", "PMID:22607692", "PMID:23041983", "PMID:23152411", "PMID:23543977", "PMID:23577329", "PMID:23649929", "PMID:23921349", "PMID:24365689", "PMID:24440755", "PMID:365327", "PMID:366135", "PMID:366137", "PMID:669135", "PMID:6995092", "PMID:6995094", "PMID:7051554", "PMID:827785", "Patent:US3274209", "Patent:US3565907", "Patent:US3579530", "Reaxys:4233256", "VSDB:1798", "Wikipedia:Levamisole" ; oboInOwl:hasExactSynonym "(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole", "(-)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole", "(-)-tetramisole", "(S)-(-)-levamisole", "(S)-(-)-tetramisole", "(S)-2,3,5,6-tetrahydro-6-phenylimidazo[2,1-b]thiazole", "Ketrax", "Lepuron", "Levomysol", "Levovermax", "Totalon", "Wormicid", "levamisol", "levamisole", "levamisolum" ; oboInOwl:id "CHEBI:6432" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "levamisole" ; rdfs:subClassOf obo:CHEBI_77278, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35444 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35842 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50847 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63332 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_77282 ] . obo:CHEBI_64365 obo:IAO_0000115 "An organic amino compound in which an aminoalkyl group is linked to an arene." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "aralkylamino compounds" ; oboInOwl:id "CHEBI:64365" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aralkylamino compound" ; rdfs:subClassOf obo:CHEBI_50047 . obo:CHEBI_64459 obo:IAO_0000115 "An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "biaryls" ; oboInOwl:id "CHEBI:64459" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "biaryl" ; rdfs:subClassOf obo:CHEBI_33659 . obo:CHEBI_64577 obo:IAO_0000115 "A food additive which is added to flour or dough to improve baking quality and/or colour." ; oboInOwl:hasDbXref "Wikipedia:Flour_treatment_agent" ; oboInOwl:hasExactSynonym "flour treatment agent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dough improver", "dough improvers", "improving agent", "improving agents" ; oboInOwl:id "CHEBI:64577" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "flour treatment agent" ; rdfs:subClassOf obo:CHEBI_64047 . obo:CHEBI_64641 obo:IAO_0000115 "An inorganic cation with a valency of two." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:64641" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "divalent inorganic cation" ; rdfs:subClassOf obo:CHEBI_36915 . obo:CHEBI_64708 obo:IAO_0000115 "An organic molecular entity containing a single carbon atom (C1)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "one-carbon compounds" ; oboInOwl:id "CHEBI:64708" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "one-carbon compound" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_64709 obo:IAO_0000115 "Any organic molecular entity that is acidic and contains carbon in covalent linkage." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic acids" ; oboInOwl:id "CHEBI:64709" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic acid" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_64857 obo:IAO_0000115 "The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it." ; oboInOwl:hasDbXref "Wikipedia:Cosmetics" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cosmetic component", "cosmetics" ; oboInOwl:id "CHEBI:64857" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cosmetic" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_64909 obo:IAO_0000115 "Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism." ; oboInOwl:hasDbXref "Wikipedia:Poison" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "poisonous agent", "poisonous agents", "poisonous substance", "poisonous substances", "poisons", "toxic agent", "toxic agents", "toxic substance", "toxic substances" ; oboInOwl:id "CHEBI:64909" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "poison" ; rdfs:subClassOf obo:CHEBI_24432 . obo:CHEBI_64911 obo:IAO_0000115 "Any compound that inhibits cell division (mitosis)." ; oboInOwl:hasDbXref "Wikipedia:Mitotic_inhibitor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimitotics", "mitosis inhibitor", "mitosis inhibitors", "mitotic inhibitor", "mitotic inhibitors" ; oboInOwl:id "CHEBI:64911" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimitotic" ; rdfs:subClassOf obo:CHEBI_52210 . obo:CHEBI_64915 obo:IAO_0000115 "An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antiplasmodial agent", "antiplasmodial agents", "antiplasmodial drugs", "antiplasmodium agent", "antiplasmodium agents", "antiplasmodium drug", "antiplasmodium drugs" ; oboInOwl:id "CHEBI:64915" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antiplasmodial drug" ; rdfs:subClassOf obo:CHEBI_35820 . obo:CHEBI_65255 obo:IAO_0000115 "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food preservatives" ; oboInOwl:id "CHEBI:65255" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "food preservative" ; rdfs:subClassOf obo:CHEBI_64047 . obo:CHEBI_65256 obo:IAO_0000115 "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "antimicrobial food preservatives", "antimicrobial preservative", "antimicrobial preservatives" ; oboInOwl:id "CHEBI:65256" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "antimicrobial food preservative" ; rdfs:subClassOf obo:CHEBI_33281, obo:CHEBI_65255 . obo:CHEBI_65259 obo:IAO_0000115 "A compound that inhibits the action of gamma-aminobutyric acid." ; oboInOwl:hasDbXref "Wikipedia:GABA_antagonist" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "GABA antagonists", "gamma-aminobutyric acid receptor antagonist", "gamma-aminobutyric acid receptor antagonists" ; oboInOwl:id "CHEBI:65259" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "GABA antagonist" ; rdfs:subClassOf obo:CHEBI_48706, obo:CHEBI_51374 . obo:CHEBI_65296 obo:IAO_0000115 "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "H3NR" ; chebi:mass "17.031" ; chebi:monoisotopicmass "17.02655" ; chebi:smiles "[NH3+][*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a primary amine", "substituted ammonium" ; oboInOwl:id "CHEBI:65296" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "primary ammonium ion" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_50994 ] . obo:CHEBI_67079 obo:IAO_0000115 "Any compound that has anti-inflammatory effects." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "anti-inflammatory agents", "antiinflammatory agent", "antiinflammatory agents" ; oboInOwl:id "CHEBI:67079" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "anti-inflammatory agent" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_67114 obo:IAO_0000115 "A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction." ; oboInOwl:hasDbXref "PMID:30679133", "PMID:30684528", "PMID:31840405", "PMID:8597061", "Wikipedia:Ryanodine_receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "RyR activator", "RyR activators", "RyR agonist", "RyR agonists", "RyRs activator", "RyRs agonist", "ryanodine receptor activator", "ryanodine receptor activators" ; oboInOwl:id "CHEBI:67114" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ryanodine receptor agonist" ; rdfs:subClassOf obo:CHEBI_38809 . obo:CHEBI_67142 obo:IAO_0000115 "A molecule that can substitute for a normal nucleobase in nucleic acids." ; oboInOwl:hasDbXref "Wikipedia:Base_analog" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "base analog", "base analogs", "base analogue", "base analogues", "nucleobase analog", "nucleobase analogs", "nucleobase analogues" ; oboInOwl:id "CHEBI:67142" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "nucleobase analogue" ; rdfs:subClassOf obo:CHEBI_33832 . obo:CHEBI_6835 obo:IAO_0000115 "A carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime." ; chebi:charge "0" ; chebi:formula "C5H10N2O2S" ; chebi:inchi "InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)" ; chebi:inchikey "UHXUZOCRWCRNSJ-UHFFFAOYSA-N" ; chebi:mass "162.21118" ; chebi:monoisotopicmass "162.04630" ; chebi:smiles "CNC(=O)ON=C(C)SC" ; oboInOwl:hasDbXref "Beilstein:2042050", "CAS:16752-77-5", "HMDB:HMDB0031804", "KEGG:C11196", "LINCS:LSM-24991", "PMID:11327381", "PMID:11758270", "PPDB:458", "Pesticides:methomyl", "Reaxys:2042050", "Wikipedia:Methomyl" ; oboInOwl:hasExactSynonym "Methomyl", "methyl N-(methylcarbamoyloxy)ethanimidothioate" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "1-(Methylthio)acetaldehyde O-methylcarbamoyloxime", "1-(Methylthio)ethylideneamino methylcarbamate", "Lannate", "Methomyl lannate", "N-(((methylamino)carbonyl)oxy)ethanimidothioic acid methyl ester", "S-Methyl N-(methylcarbamoyloxy)thioacetimidate" ; oboInOwl:id "CHEBI:6835" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methomyl" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_22327, obo:CHEBI_23003, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_22153 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_24852 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25491 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_33286 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37733 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_38462 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_38534 ], [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_45379 ] . obo:CHEBI_68452 obo:IAO_0000115 "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen." ; oboInOwl:hasDbXref "Wikipedia:Azole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "azoles" ; oboInOwl:id "CHEBI:68452" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "azole" ; rdfs:subClassOf obo:CHEBI_38101, obo:CHEBI_38179 . obo:CHEBI_68495 obo:IAO_0000115 "Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Type I cell-death inducer", "Type I cell-death inducers", "Type I programmed cell-death inducer", "Type I programmed cell-death inducers", "apoptosis inducers" ; oboInOwl:id "CHEBI:68495" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "apoptosis inducer" ; rdfs:subClassOf obo:CHEBI_52206 . obo:CHEBI_7035 obo:IAO_0000115 "A member of the class of isoxazoles that is 1,2-oxazol-3(2H)-one substituted by an aminomethyl group at position 5. It has been isolated from mushrooms of the genus Amanita." ; chebi:charge "0" ; chebi:formula "C4H6N2O2" ; chebi:inchi "InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7)" ; chebi:inchikey "ZJQHPWUVQPJPQT-UHFFFAOYSA-N" ; chebi:mass "114.10260" ; chebi:monoisotopicmass "114.04293" ; chebi:smiles "NCc1cc(=O)[nH]o1" ; oboInOwl:hasDbXref "Beilstein:774694", "CAS:2763-96-4", "KEGG:C08311", "KNApSAcK:C00001423", "PMID:18599311", "PMID:21427702", "PMID:21751026", "PMID:2181052", "PMID:22049436", "PMID:24259680", "PMID:24316475", "PMID:24473816", "Reaxys:774694", "Wikipedia:Muscimol" ; oboInOwl:hasExactSynonym "5-(aminomethyl)-1,2-oxazol-3(2H)-one", "Muscimol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "5-(aminomethyl)-3(2H)-isoxazolone" ; oboInOwl:id "CHEBI:7035" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "muscimol" ; rdfs:subClassOf obo:CHEBI_22315, obo:CHEBI_50994, obo:CHEBI_55373, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_146270 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_51373 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_76946 ] . obo:CHEBI_71232 obo:IAO_0000115 "An antagonist at any adenosine receptor." ; oboInOwl:hasDbXref "Wikipedia:Adenosine_receptor" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adenosine receptor antagonists" ; oboInOwl:id "CHEBI:71232" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "adenosine receptor antagonist" ; rdfs:subClassOf obo:CHEBI_48706 . obo:CHEBI_71300 obo:IAO_0000115 "An enzyme inhibitor that inhibits the action of a transferase (EC 2.*)" ; oboInOwl:hasDbXref "Wikipedia:Transferase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2 inhibitor", "EC 2 inhibitors", "EC 2.* (transferase) inhibitors", "EC 2.* inhibitor", "EC 2.* inhibitors", "transferase inhibitor", "transferase inhibitors" ; oboInOwl:id "CHEBI:71300" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.* (transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_71666 obo:IAO_0000115 "An amino-acid anion in which the amino group is situated gamma- to the carboxylate group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "gamma-amino acid anions" ; oboInOwl:id "CHEBI:71666" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "gamma-amino acid anion" ; rdfs:subClassOf obo:CHEBI_37022, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_33707 ] . obo:CHEBI_72600 obo:IAO_0000115 "A cyclic ketal in which the ketal carbon is the only common atom of two rings." ; oboInOwl:hasDbXref "PMID:19262920", "PMID:20024126", "PMID:21076755", "PMID:21604735", "PMID:21860857", "PMID:22421755" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "spiroacetal", "spiroacetals", "spiroketals" ; oboInOwl:id "CHEBI:72600" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "spiroketal" ; rdfs:subClassOf obo:CHEBI_37948, obo:CHEBI_59779 . obo:CHEBI_72695 obo:IAO_0000115 "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic compound", "organic compounds", "organic molecules" ; oboInOwl:id "CHEBI:72695" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic molecule" ; rdfs:subClassOf obo:CHEBI_25367, obo:CHEBI_50860 . obo:CHEBI_73216 obo:IAO_0000115 "Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*)." ; oboInOwl:hasAlternativeId "CHEBI:76765" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.6 inhibitor", "EC 3.6 inhibitors", "EC 3.6.* (hydrolases acting on acid anhydrides) inhibitors", "EC 3.6.* inhibitor", "EC 3.6.* inhibitors", "EC 3.6.*.* inhibitor", "EC 3.6.*.* inhibitors", "acid anhydride hydrolase inhibitor", "acid anhydride hydrolase inhibitors", "inhibitor of hydrolase acting on acid anhydride (EC 3.6.*)", "inhibitors of hydrolase acting on acid anhydride (EC 3.6.*)" ; oboInOwl:id "CHEBI:73216" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor" ; rdfs:subClassOf obo:CHEBI_76759 . obo:CHEBI_73333 obo:IAO_0000115 "An acaricide that kills mites of the genus Sarcoptes." ; oboInOwl:hasDbXref "Wikipedia:Scabicide" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "scabicides" ; oboInOwl:id "CHEBI:73333" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "scabicide" ; rdfs:subClassOf obo:CHEBI_22153 . obo:CHEBI_73398 obo:IAO_0000115 "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring." ; chebi:charge "0" ; chebi:formula "C8N" ; chebi:mass "110.09230" ; chebi:monoisotopicmass "110.00307" ; chebi:smiles "C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:73398" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "indole skeleton" ; rdfs:subClassOf obo:CHEBI_73541 . obo:CHEBI_73541 obo:IAO_0000115 "A bicyclic organic group that contains both carbon and hetero atoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organic heterobicyclic rings" ; oboInOwl:id "CHEBI:73541" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organic heterobicyclic ring" ; rdfs:subClassOf obo:CHEBI_52845 . obo:CHEBI_73693 obo:IAO_0000115 "A carbonyl compound produced as a water-soluble byproduct when fatty acids are broken down for energy in the liver. There are three endogenous ketone bodies: acetone, acetoacetic acid, and (R)-3-hydroxybutyric acid; others may be produced as a result of the metabolism of synthetic triglycerides." ; oboInOwl:hasDbXref "PMID:10634967", "PMID:19159745", "PMID:22259088", "PMID:22268909", "PMID:22524563", "PMID:22879057", "PMID:23082721", "PMID:23148246", "PMID:23396451", "PMID:23466063", "PMID:23557707", "Wikipedia:Ketone_body" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "ketone bodies" ; oboInOwl:id "CHEBI:73693" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "ketone body" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_36586, obo:CHEBI_61697, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_25212 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_63726 ] . obo:CHEBI_74213 obo:IAO_0000115 "An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1)." ; oboInOwl:hasDbXref "Wikipedia:Ribonucleoside-diphosphate_reductase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitor", "2'-deoxyribonucleoside-diphosphate:thioredoxin-disulfide 2'-oxidoreductase inhibitors", "ADP reductase inhibitor", "ADP reductase inhibitors", "CDP reductase inhibitor", "CDP reductase inhibitors", "EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitors", "EC 1.17.4.1 inhibitor", "EC 1.17.4.1 inhibitors", "RR inhibitor", "RR inhibitors", "UDP reductase inhibitor", "UDP reductase inhibitors", "nucleoside diphosphate reductase inhibitor", "nucleoside diphosphate reductase inhibitors", "ribonucleoside diphosphate reductase inhibitor", "ribonucleoside diphosphate reductase inhibitors", "ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitor", "ribonucleoside-diphosphate reductase (EC 1.17.4.1) inhibitors", "ribonucleoside-diphosphate reductase inhibitor", "ribonucleoside-diphosphate reductase inhibitors", "ribonucleotide diphosphate reductase inhibitor", "ribonucleotide diphosphate reductase inhibitors", "ribonucleotide reductase inhibitor", "ribonucleotide reductase inhibitors" ; oboInOwl:id "CHEBI:74213" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76848 . obo:CHEBI_74634 obo:IAO_0000115 "Any steroid lactone that is a C23 steroid with a five-membered lactone ring at C-17 and its substituted derivatives. They form the aglycone constituents of cardiac glycosides." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:74634" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cardenolides" ; rdfs:subClassOf obo:CHEBI_26766, obo:CHEBI_50523 . obo:CHEBI_74783 obo:IAO_0000115 "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions." ; oboInOwl:hasDbXref "Wikipedia:Astringent" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "adstringent", "adstringents", "astringents" ; oboInOwl:id "CHEBI:74783" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "astringent" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_75763 obo:IAO_0000115 "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "eukaryotic metabolites" ; oboInOwl:id "CHEBI:75763" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "eukaryotic metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_75767 obo:IAO_0000115 "Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals." ; oboInOwl:hasAlternativeId "CHEBI:77721", "CHEBI:77743" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "animal metabolites" ; oboInOwl:id "CHEBI:75767" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "animal metabolite" ; rdfs:subClassOf obo:CHEBI_75763 . obo:CHEBI_75768 obo:IAO_0000115 "Any animal metabolite produced during a metabolic reaction in mammals." ; oboInOwl:hasAlternativeId "CHEBI:77464", "CHEBI:77744" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "mammalian metabolites" ; oboInOwl:id "CHEBI:75768" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mammalian metabolite" ; rdfs:subClassOf obo:CHEBI_75767 . obo:CHEBI_75771 obo:IAO_0000115 "Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Mus musculus metabolite", "Mus musculus metabolites", "mouse metabolites" ; oboInOwl:id "CHEBI:75771" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "mouse metabolite" ; rdfs:subClassOf obo:CHEBI_75768 . obo:CHEBI_75772 obo:IAO_0000115 "Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae)." ; oboInOwl:hasAlternativeId "CHEBI:76949", "CHEBI:76951" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "S. cerevisiae metabolite", "S. cerevisiae metabolites", "S. cerevisiae secondary metabolite", "S. cerevisiae secondary metabolites", "Saccharomyces cerevisiae metabolites", "Saccharomyces cerevisiae secondary metabolites", "baker's yeast metabolite", "baker's yeast metabolites", "baker's yeast secondary metabolite", "baker's yeast secondary metabolites" ; oboInOwl:id "CHEBI:75772" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "Saccharomyces cerevisiae metabolite" ; rdfs:subClassOf obo:CHEBI_76946 . obo:CHEBI_75787 obo:IAO_0000115 "Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "prokaryotic metabolites" ; oboInOwl:id "CHEBI:75787" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "prokaryotic metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_76206 obo:IAO_0000115 "Any metabolite produced by metabolism of a xenobiotic compound." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "xenobiotic metabolites" ; oboInOwl:id "CHEBI:76206" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "xenobiotic metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_76413 obo:IAO_0000115 "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'." ; oboInOwl:hasDbXref "Wikipedia:Greenhouse_gas" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "greenhouse gases" ; oboInOwl:id "CHEBI:76413" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "greenhouse gas" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_76414 obo:IAO_0000115 "A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans." ; oboInOwl:hasDbXref "PMID:22519407", "PMID:24001847" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "propellants" ; oboInOwl:id "CHEBI:76414" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "propellant" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_76507 obo:IAO_0000115 "Any metabolite produced during a metabolic reaction in marine macro- and microorganisms." ; oboInOwl:hasAlternativeId "CHEBI:77078" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "marine metabolites" ; oboInOwl:id "CHEBI:76507" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "marine metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_76661 obo:IAO_0000115 "A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.3.* (acyltransferase) inhibitors", "EC 2.3.* inhibitor", "EC 2.3.* inhibitors", "acyltransferase inhibitor", "acyltransferase inhibitors" ; oboInOwl:id "CHEBI:76661" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.3.* (acyltransferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_71300 . obo:CHEBI_76663 obo:IAO_0000115 "A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitors", "EC 2.5.1.* inhibitor", "EC 2.5.1.* inhibitors", "alkyl/aryl (non-methyl) transferase inhibitor", "alkyl/aryl (non-methyl) transferase inhibitors", "non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitor", "non-methyl alkyl/aryl transferase (EC 2.5.1.*) inhibitors", "non-methyl alkyl/aryl transferase inhibitor", "non-methyl alkyl/aryl transferase inhibitors", "non-methyl-alkyl or aryl transferase inhibitor", "non-methyl-alkyl or aryl transferase inhibitors" ; oboInOwl:id "CHEBI:76663" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76834 . obo:CHEBI_76668 obo:IAO_0000115 "A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.* (P-containing group transferase) inhibitors", "EC 2.7.* (phosphorus-containing group transferase) inhibitor", "EC 2.7.* (phosphorus-containing group transferase) inhibitors", "EC 2.7.* inhibitor", "EC 2.7.* inhibitors", "phosphorus-containing group transferase (EC 2.7.*) inhibitor", "phosphorus-containing group transferase (EC 2.7.*) inhibitors", "phosphorus-containing group transferase inhibitor", "phosphorus-containing group transferase inhibitors" ; oboInOwl:id "CHEBI:76668" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.7.* (P-containing group transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_71300 . obo:CHEBI_76710 obo:IAO_0000115 "An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation." ; oboInOwl:hasDbXref "Wikipedia:Lyase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 4.* (lyase) inhibitors", "EC 4.* inhibitor", "EC 4.* inhibitors", "EC 4.*.*.* inhibitor", "EC 4.*.*.* inhibitors", "lyase (EC 4.*) inhibitor", "lyase (EC 4.*) inhibitorS", "lyase inhibitor", "lyase inhibitors" ; oboInOwl:id "CHEBI:76710" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 4.* (lyase) inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_76713 obo:IAO_0000115 "A lyase inhibitor which inhibits the action of a C-N lyase (EC 4.3.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "C-N lyase (EC 4.3.*) inhibitor", "C-N lyase (EC 4.3.*) inhibitors", "C-N lyase inhibitor", "C-N lyase inhibitors", "EC 4.3.* (C-N lyase) inhibitors", "EC 4.3.* inhibitor", "EC 4.3.* inhibitors" ; oboInOwl:id "CHEBI:76713" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 4.3.* (C-N lyase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76710 . obo:CHEBI_76725 obo:IAO_0000115 "An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*)." ; oboInOwl:hasDbXref "Wikipedia:Oxidoreductase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 1.* (oxidoreductase) inhibitors", "EC 1.* inhibitor", "EC 1.* inhibitors", "oxidoreductase (EC 1.*) inhibitor", "oxidoreductase (EC 1.*) inhibitors", "oxidoreductase inhibitor", "oxidoreductase inhibitors" ; oboInOwl:id "CHEBI:76725" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 1.* (oxidoreductase) inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_76744 obo:IAO_0000115 "An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH2 (EC 1.17.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitors", "EC 1.17.* inhibitor", "EC 1.17.* inhibitors", "oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitor", "oxidoreductase acting on CH or CH2 (EC 1.17.*) inhibitors", "oxidoreductase acting on CH or CH2 inhibitor", "oxidoreductase acting on CH or CH2 inhibitors" ; oboInOwl:id "CHEBI:76744" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor" ; rdfs:subClassOf obo:CHEBI_76725 . obo:CHEBI_76759 obo:IAO_0000115 "Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*)." ; oboInOwl:hasDbXref "Wikipedia:Hydrolase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.* (hydrolase) inhibitors", "EC 3.* inhibitor", "EC 3.* inhibitors", "EC 3.*.*.* inhibitor", "EC 3.*.*.* inhibitors", "hydrolase (EC 3.*) inhibitor", "hydrolase (EC 3.*) inhibitors", "hydrolase inhibitor", "hydrolase inhibitors" ; oboInOwl:id "CHEBI:76759" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.* (hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_76760 obo:IAO_0000115 "A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.* (ester hydrolase) inhibitors", "EC 3.1.* inhibitor", "EC 3.1.* inhibitors", "ester hydrolase (EC 3.1.*) inhibitor", "ester hydrolase (EC 3.1.*) inhibitors", "ester hydrolase inhibitor", "ester hydrolase inhibitors" ; oboInOwl:id "CHEBI:76760" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.1.* (ester hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76759 . obo:CHEBI_76764 obo:IAO_0000115 "Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitor", "EC 3.5.* (hydrolase acting on non-peptide C-N bond) inhibitors", "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitor", "EC 3.5.* (hydrolases acting on C-N bonds, other than peptide bonds) inhibitors", "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitors", "EC 3.5.* inhibitor", "EC 3.5.* inhibitors" ; oboInOwl:id "CHEBI:76764" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor" ; rdfs:subClassOf obo:CHEBI_76759 . obo:CHEBI_76773 obo:IAO_0000115 "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.1.* (carboxylic ester hydrolase) inhibitors", "EC 3.1.1.* inhibitor", "EC 3.1.1.* inhibitors", "carboxylic ester hydrolase (EC 3.1.1.*) inhibitor", "carboxylic ester hydrolase (EC 3.1.1.*) inhibitors" ; oboInOwl:id "CHEBI:76773" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.1.1.* (carboxylic ester hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76760 . obo:CHEBI_76775 obo:IAO_0000115 "An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.1.3.* (phosphoric monoester hydrolase) inhibitors", "EC 3.1.3.* inhibitor", "EC 3.1.3.* inhibitors", "inhibitor of phosphoric monoester hydrolase", "inhibitor of phosphoric monoester hydrolase (EC 3.1.3.*)", "inhibitors of phosphoric monoester hydrolase", "inhibitors of phosphoric monoester hydrolase (EC 3.1.3.*)", "phosphoric monoester hydrolase (EC 3.1.3.*) inhibitor", "phosphoric monoester hydrolase (EC 3.1.3.*) inhibitors", "phosphoric monoester hydrolase inhibitor", "phosphoric monoester hydrolase inhibitors" ; oboInOwl:id "CHEBI:76775" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76760 . obo:CHEBI_76779 obo:IAO_0000115 "Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.4.21.26 (prolyl oligopeptidase) inhibitors", "EC 3.4.21.26 inhibitor", "EC 3.4.21.26 inhibitors", "endoprolylpeptidase inhibitor", "endoprolylpeptidase inhibitors", "post-proline cleaving enzyme inhibitor", "post-proline cleaving enzyme inhibitors", "post-proline endopeptidase inhibitor", "post-proline endopeptidase inhibitors", "proline endopeptidase inhibitor", "proline endopeptidase inhibitors", "proline-specific endopeptidase inhibitor", "proline-specific endopeptidase inhibitors", "prolyl endopeptidase inhibitor", "prolyl endopeptidase inhibitors", "prolyl oligopeptidase (EC 3.4.21.26) inhibitor", "prolyl oligopeptidase (EC 3.4.21.26) inhibitors", "prolyl oligopeptidase inhibitor" ; oboInOwl:id "CHEBI:76779" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.4.21.26 (prolyl oligopeptidase) inhibitor" ; rdfs:subClassOf obo:CHEBI_5924 . obo:CHEBI_76797 obo:IAO_0000115 "An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18)." ; oboInOwl:hasDbXref "Wikipedia:Glutathione_S-transferase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.5.1.18 (glutathione transferase) inhibitors", "EC 2.5.1.18 inhibitor", "EC 2.5.1.18 inhibitors", "RX:glutathione R-transferase inhibitor", "RX:glutathione R-transferase inhibitors", "S-(hydroxyalkyl)glutathione lyase inhibitor", "S-(hydroxyalkyl)glutathione lyase inhibitors", "glutathione S-alkyl transferase inhibitor", "glutathione S-alkyl transferase inhibitors", "glutathione S-alkyltransferase inhibitor", "glutathione S-alkyltransferase inhibitors", "glutathione S-aralkyltransferase inhibitor", "glutathione S-aralkyltransferase inhibitors", "glutathione S-aryltransferase inhibitor", "glutathione S-aryltransferase inhibitors", "glutathione S-transferase inhibitor", "glutathione S-transferase inhibitors", "glutathione transferase (EC 2.5.1.18) inhibitor", "glutathione transferase (EC 2.5.1.18) inhibitors", "glutathione transferase inhibitor", "glutathione transferase inhibitors" ; oboInOwl:id "CHEBI:76797" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.5.1.18 (glutathione transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76663 . obo:CHEBI_76807 obo:IAO_0000115 "An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitors", "EC 3.5.1.* inhibitor", "EC 3.5.1.* inhibitors", "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitor", "non-peptide linear amide C-N hydrolase (EC 3.5.1.*) inhibitors" ; oboInOwl:id "CHEBI:76807" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76764 . obo:CHEBI_76812 obo:IAO_0000115 "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.11.* (protein-serine/threonine kinase) inhibitors", "EC 2.7.11.* inhibitor", "EC 2.7.11.* inhibitors", "protein-serine/threonine kinase (EC 2.7.11.*) inhibitor", "protein-serine/threonine kinase (EC 2.7.11.*) inhibitors", "protein-serine/threonine kinase inhibitor", "protein-serine/threonine kinase inhibitors" ; oboInOwl:id "CHEBI:76812" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.7.11.* (protein-serine/threonine kinase) inhibitor" ; rdfs:subClassOf obo:CHEBI_37699 . obo:CHEBI_76815 obo:IAO_0000115 "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.7.* (nucleotidyltransferase) inhibitors", "inhibitor of nucleotidyltransferases", "inhibitor of nucleotidyltransferases (EC 2.7.7.*)", "inhibitors of nucleotidyltransferases", "inhibitors of nucleotidyltransferases (EC 2.7.7.*)", "nucleotidyltransferase (EC 2.7.7.*) inhibitor", "nucleotidyltransferase (EC 2.7.7.*) inhibitors", "nucleotidyltransferase inhibitor", "nucleotidyltransferase inhibitors" ; oboInOwl:id "CHEBI:76815" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.7.7.* (nucleotidyltransferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76668 . obo:CHEBI_76816 obo:IAO_0000115 "An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitors", "EC 2.7.8.* inhibitor", "EC 2.7.8.* inhibitors" ; oboInOwl:id "CHEBI:76816" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor" ; rdfs:subClassOf obo:CHEBI_76668 . obo:CHEBI_76832 obo:IAO_0000115 "An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 4.3.1.* (ammonia-lyase) inhibitors", "EC 4.3.1.* (ammonia-lyases) inhibitor", "EC 4.3.1.* (ammonia-lyases) inhibitors", "EC 4.3.1.* inhibitor", "EC 4.3.1.* inhibitors", "ammonia-lyase (EC 4.3.1.*) inhibitor", "ammonia-lyase (EC 4.3.1.*) inhibitors", "ammonia-lyase inhibitor", "ammonia-lyase inhibitors" ; oboInOwl:id "CHEBI:76832" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 4.3.1.* (ammonia-lyase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76713 . obo:CHEBI_76834 obo:IAO_0000115 "An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitors", "EC 2.5.* inhibitor", "EC 2.5.* inhibitors", "non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitor", "non-methyl-alkyl or aryl transferase (EC 2.5.*) inhibitors" ; oboInOwl:id "CHEBI:76834" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor" ; rdfs:subClassOf obo:CHEBI_71300 . obo:CHEBI_76848 obo:IAO_0000115 "An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitors", "EC 1.17.4.* inhibitor", "EC 1.17.4.* inhibitors", "oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitor", "oxidoreductase acting on CH or CH2 with a disulfide as acceptor (EC 1.17.4.*) inhibitors" ; oboInOwl:id "CHEBI:76848" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor" ; rdfs:subClassOf obo:CHEBI_76744 . obo:CHEBI_76895 obo:IAO_0000115 "An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitors", "EC 3.6.3.* inhibitor", "EC 3.6.3.* inhibitors", "acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitor", "acid anhydride hydrolase catalysing transmembrane movement of substances (EC 3.6.3.*) inhibitors" ; oboInOwl:id "CHEBI:76895" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor" ; rdfs:subClassOf obo:CHEBI_73216 . obo:CHEBI_76924 obo:IAO_0000115 "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms." ; oboInOwl:hasAlternativeId "CHEBI:75766", "CHEBI:76925" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "plant metabolites", "plant secondary metabolites" ; oboInOwl:id "CHEBI:76924" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "plant metabolite" ; rdfs:subClassOf obo:CHEBI_75763 . obo:CHEBI_76932 obo:IAO_0000115 "An enzyme inhibitor that interferes with one or more steps in a metabolic pathway." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "metabolic pathway inhibitor", "metabolic pathway inhibitors", "pathway inhibitors" ; oboInOwl:id "CHEBI:76932" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pathway inhibitor" ; rdfs:subClassOf obo:CHEBI_23924 . obo:CHEBI_76946 obo:IAO_0000115 "Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds." ; oboInOwl:hasAlternativeId "CHEBI:75765", "CHEBI:76947" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fungal metabolites" ; oboInOwl:id "CHEBI:76946" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fungal metabolite" ; rdfs:subClassOf obo:CHEBI_75763 . obo:CHEBI_76967 obo:IAO_0000115 "Any human metabolite produced by metabolism of a xenobiotic compound in humans." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "human xenobiotic metabolites" ; oboInOwl:id "CHEBI:76967" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "human xenobiotic metabolite" ; rdfs:subClassOf obo:CHEBI_76206, obo:CHEBI_77746 . obo:CHEBI_76969 obo:IAO_0000115 "Any prokaryotic metabolite produced during a metabolic reaction in bacteria." ; oboInOwl:hasAlternativeId "CHEBI:75760", "CHEBI:76970" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:76969" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bacterial metabolite" ; rdfs:subClassOf obo:CHEBI_75787 . obo:CHEBI_76971 obo:IAO_0000115 "Any bacterial metabolite produced during a metabolic reaction in Escherichia coli." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "E.coli metabolite", "E.coli metabolites", "Escherichia coli metabolites" ; oboInOwl:id "CHEBI:76971" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "Escherichia coli metabolite" ; rdfs:subClassOf obo:CHEBI_76969 . obo:CHEBI_76976 obo:IAO_0000115 "Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "bacterial xenobiotic metabolites" ; oboInOwl:id "CHEBI:76976" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "bacterial xenobiotic metabolite" ; rdfs:subClassOf obo:CHEBI_76206, obo:CHEBI_76969 . obo:CHEBI_76988 obo:IAO_0000115 "A synthetic or semi-synthetic compound that has oestrogenic activity." ; oboInOwl:hasDbXref "Wikipedia:Xenoestrogen" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "xenoestrogens" ; oboInOwl:id "CHEBI:76988" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "xenoestrogen" ; rdfs:subClassOf obo:CHEBI_138015, obo:CHEBI_50114 . obo:CHEBI_77022 obo:IAO_0000115 "An EC 2.3.* (acyltransferase) inhibitor that interferes with the action of an acyltransferase which converts the acyl group to an alkyl group on transfer (EC 2.3.3.*)." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitors", "EC 2.3.3.* inhibitor", "EC 2.3.3.* inhibitors", "acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitor", "acyltransferase converting acyl to alkyl group on transfer (EC 2.3.3.*) inhibitors" ; oboInOwl:id "CHEBI:77022" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor" ; rdfs:subClassOf obo:CHEBI_76661 . obo:CHEBI_77023 obo:IAO_0000115 "An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of citrate (Si)-synthase, EC 2.3.3.1." ; oboInOwl:hasDbXref "Wikipedia:Citrate_synthase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(R)-citrate synthase inhibitor", "(R)-citrate synthase inhibitors", "EC 2.3.3.1 (citrate (Si)-synthase) inhibitor", "EC 2.3.3.1 (citrate (Si)-synthase) inhibitors", "EC 2.3.3.1 [citrate (Si)-synthase] inhibitors", "EC 2.3.3.1 inhibitor", "EC 2.3.3.1 inhibitors", "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitor", "acetyl-CoA:oxaloacetate C-acetyltransferase [thioester-hydrolysing, (pro-S)-carboxymethyl forming] inhibitors", "citrate (Si)-synthase (EC 2.3.3.1) inhibitor", "citrate (Si)-synthase (EC 2.3.3.1) inhibitors", "citrate condensing enzyme inhibitor", "citrate condensing enzyme inhibitors", "citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitor", "citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA] inhibitors", "citrate oxaloacetate-lyase, CoA-acetylating inhibitor", "citrate oxaloacetate-lyase, CoA-acetylating inhibitors", "citrate synthase inhibitor", "citrate synthase inhibitors", "citrate synthetase inhibitor", "citrate synthetase inhibitors", "citric synthase inhibitor", "citric synthase inhibitors", "citric-condensing enzyme inhibitor", "citric-condensing enzyme inhibitors", "citrogenase inhibitor", "citrogenase inhibitors", "condensing enzyme inhibitor", "condensing enzyme inhibitors", "oxalacetic transacetase inhibitor", "oxalacetic transacetase inhibitors", "oxaloacetate transacetase inhibitor", "oxaloacetate transacetase inhibitors" ; oboInOwl:id "CHEBI:77023" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 2.3.3.1 [citrate (Si)-synthase] inhibitor" ; rdfs:subClassOf obo:CHEBI_77022 . obo:CHEBI_77024 obo:IAO_0000115 "An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41)." ; oboInOwl:hasDbXref "Wikipedia:4-nitrophenylphosphatase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4-nitrophenylphosphatase (EC 3.1.3.41) inhibitor", "4-nitrophenylphosphatase (EC 3.1.3.41) inhibitors", "4-nitrophenylphosphate phosphohydrolase inhibitor", "4-nitrophenylphosphate phosphohydrolase inhibitors", "EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitors", "EC 3.1.3.41 inhibitor", "EC 3.1.3.41 inhibitors", "Ecto-p-nitrophenyl phosphatase inhibitor", "Ecto-p-nitrophenyl phosphatase inhibitors", "K-pNPPase inhibitor", "K-pNPPase inhibitors", "NPPase inhibitor", "NPPase inhibitors", "PNPPase inhibitor", "PNPPase inhibitors", "nitrophenyl phosphatase inhibitor", "nitrophenyl phosphatase inhibitors", "p-nitrophenylphosphatase inhibitor", "p-nitrophenylphosphatase inhibitors", "p-nitrophenylphosphate phosphohydrolase inhibitor", "p-nitrophenylphosphate phosphohydrolase inhibitors", "para-nitrophenyl phosphatase inhibitor", "para-nitrophenyl phosphatase inhibitors", "xK-pNPPase inhibitors" ; oboInOwl:id "CHEBI:77024" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76775 . obo:CHEBI_77035 obo:IAO_0000115 "Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex." ; oboInOwl:hasDbXref "PMID:17594730" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "expectorants" ; oboInOwl:id "CHEBI:77035" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "expectorant" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_77278 obo:IAO_0000115 "An imidazothiazole that is imidazo[2,1-b][1,3]thiazole in which the double bonds at the 2-3 and 5-6 positions have been reduced to single bonds and in which one of the hydrogens at position 6 is replaced by a phenyl group." ; chebi:charge "0" ; chebi:formula "C11H12N2S" ; chebi:inchi "InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2" ; chebi:inchikey "HLFSDGLLUJUHTE-UHFFFAOYSA-N" ; chebi:mass "204.29100" ; chebi:monoisotopicmass "204.07212" ; chebi:smiles "C1CN2CC(N=C2S1)c1ccccc1" ; oboInOwl:hasDbXref "LINCS:LSM-1579" ; oboInOwl:hasExactSynonym "6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:77278" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_48909, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35703 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_78298 ] . obo:CHEBI_77282 obo:IAO_0000115 "A 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole that has R configuration." ; chebi:charge "0" ; chebi:formula "C11H12N2S" ; chebi:inchi "InChI=1S/C11H12N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-5,10H,6-8H2/t10-/m0/s1" ; chebi:inchikey "HLFSDGLLUJUHTE-JTQLQIEISA-N" ; chebi:mass "204.29100" ; chebi:monoisotopicmass "204.07212" ; chebi:smiles "C1CN2C[C@H](N=C2S1)c1ccccc1" ; oboInOwl:hasDbXref "CAS:14769-74-5", "KEGG:D03708", "PMID:189006", "PMID:22337783", "PMID:669135", "PMID:7454609", "Reaxys:5267119" ; oboInOwl:hasExactSynonym "(6R)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole", "(+)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole", "(+)-tetramisole", "(R)-(+)-tetramisole", "dexamisol", "dexamisole", "dexamisolum" ; oboInOwl:id "CHEBI:77282" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "dexamisole" ; rdfs:subClassOf obo:CHEBI_77278, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_6432 ] . obo:CHEBI_77307 obo:IAO_0000115 "Any protective agent that is able to prevent damage to the heart." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cardioprotective agents" ; oboInOwl:id "CHEBI:77307" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cardioprotective agent" ; rdfs:subClassOf obo:CHEBI_50267 . obo:CHEBI_77703 obo:IAO_0000115 "An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3)." ; oboInOwl:hasDbXref "Wikipedia:Histidine_ammonia-lyase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 4.3.1.3 (histidine ammonia-lyase) inhibitors", "EC 4.3.1.3 inhibitor", "EC 4.3.1.3 inhibitors", "L-histidine ammonia-lyase (urocanate-forming) inhibitor", "L-histidine ammonia-lyase (urocanate-forming) inhibitors", "L-histidine ammonia-lyase inhibitor", "L-histidine ammonia-lyase inhibitors", "histidase inhibitor", "histidase inhibitors", "histidinase inhibitor", "histidinase inhibitors", "histidine alpha-deaminase inhibitor", "histidine alpha-deaminase inhibitors", "histidine ammonia-lyase (EC 4.3.1.3) inhibitor", "histidine ammonia-lyase (EC 4.3.1.3) inhibitors", "histidine ammonia-lyase inhibitor", "histidine ammonia-lyase inhibitors" ; oboInOwl:id "CHEBI:77703" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 4.3.1.3 (histidine ammonia-lyase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76832 . obo:CHEBI_77746 obo:IAO_0000115 "Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens)." ; oboInOwl:hasAlternativeId "CHEBI:75770", "CHEBI:77123" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "H. sapiens metabolite", "H. sapiens metabolites", "Homo sapiens metabolite", "Homo sapiens metabolites" ; oboInOwl:id "CHEBI:77746" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "human metabolite" ; rdfs:subClassOf obo:CHEBI_75768 . obo:CHEBI_77941 obo:IAO_0000115 "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4)." ; oboInOwl:hasDbXref "Wikipedia:Amidase" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "EC 3.5.1.4 (amidase) inhibitors", "EC 3.5.1.4 inhibitor", "EC 3.5.1.4 inhibitors", "N-acetylaminohydrolase inhibitor", "N-acetylaminohydrolase inhibitors", "acylamidase inhibitor", "acylamidase inhibitors", "acylamide amidohydrolase inhibitor", "acylamide amidohydrolase inhibitors", "amidase (EC 3.5.1.4) inhibitor", "amidase (EC 3.5.1.4) inhibitors", "amidase inhibitor", "amidase inhibitors", "amidohydrolase inhibitor", "amidohydrolase inhibitors", "deaminase inhibitor", "deaminase inhibitors", "fatty acylamidase inhibitor", "fatty acylamidase inhibitors" ; oboInOwl:id "CHEBI:77941" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "EC 3.5.1.4 (amidase) inhibitor" ; rdfs:subClassOf obo:CHEBI_76807 . obo:CHEBI_77974 obo:IAO_0000115 "A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container." ; oboInOwl:hasDbXref "Wikipedia:Packaging_gas" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food packaging gases" ; oboInOwl:id "CHEBI:77974" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "food packaging gas" ; rdfs:subClassOf obo:CHEBI_64047 . obo:CHEBI_78017 obo:IAO_0000115 "A propellant that is used to expel foods from an aerosol container." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "food propellants" ; oboInOwl:id "CHEBI:78017" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "food propellant" ; rdfs:subClassOf obo:CHEBI_64047, obo:CHEBI_76414 . obo:CHEBI_78115 obo:IAO_0000115 "Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C4H7O2" ; chebi:mass "87.09718" ; chebi:monoisotopicmass "87.04460" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fatty acid 4:0" ; oboInOwl:id "CHEBI:78115" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fatty acid anion 4:0" ; rdfs:subClassOf obo:CHEBI_58951, obo:CHEBI_58953, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_140601 ] . obo:CHEBI_78116 obo:IAO_0000115 "Any saturated fatty acid anion containing 6 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3." ; chebi:charge "-1" ; chebi:formula "C6H11O2" ; chebi:mass "115.15034" ; chebi:monoisotopicmass "115.07590" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "fatty acid 6:0" ; oboInOwl:id "CHEBI:78116" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fatty acid anion 6:0" ; rdfs:subClassOf obo:CHEBI_58953, obo:CHEBI_59558 . obo:CHEBI_78295 obo:IAO_0000115 "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "dietary component", "dietary components", "food components" ; oboInOwl:id "CHEBI:78295" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "food component" ; rdfs:subClassOf obo:CHEBI_52211 . obo:CHEBI_78298 obo:IAO_0000115 "Any minor or unwanted substance introduced into the environment that can have undesired effects." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "environmental contaminants" ; oboInOwl:id "CHEBI:78298" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "environmental contaminant" ; rdfs:subClassOf obo:CHEBI_51086 . obo:CHEBI_78433 obo:IAO_0000115 "A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a \"R\" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure." ; oboInOwl:hasDbXref "Wikipedia:Refrigerant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "refrigerants" ; oboInOwl:id "CHEBI:78433" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "refrigerant" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_78608 obo:IAO_0000115 "An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3." ; chebi:charge "0" ; chebi:formula "C2H4NO2R" ; chebi:mass "74.059" ; chebi:monoisotopicmass "74.02420" ; chebi:smiles "[NH3+]C([*])C([O-])=O" ; oboInOwl:hasAlternativeId "CHEBI:83409" ; oboInOwl:hasDbXref "MetaCyc:Alpha-Amino-Acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an alpha-amino acid" ; oboInOwl:id "CHEBI:78608" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha-amino acid zwitterion" ; rdfs:subClassOf obo:CHEBI_35238, [ a owl:Restriction ; owl:onProperty chebi5:is_tautomer_of ; owl:someValuesFrom obo:CHEBI_33704 ] . obo:CHEBI_78616 obo:IAO_0000115 "Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "carbohydrates and derivatives", "carbohydrates and their derivatives" ; oboInOwl:id "CHEBI:78616" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "carbohydrates and carbohydrate derivatives" ; rdfs:subClassOf obo:CHEBI_36963 . obo:CHEBI_78675 obo:IAO_0000115 "Any metabolite produced by all living cells." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "essential metabolite", "essential metabolites", "fundamental metabolites" ; oboInOwl:id "CHEBI:78675" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "fundamental metabolite" ; rdfs:subClassOf obo:CHEBI_25212 . obo:CHEBI_78840 obo:IAO_0000115 "Any organic molecular entity that contains at least one C=C bond." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "olefinic compounds" ; oboInOwl:id "CHEBI:78840" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "olefinic compound" ; rdfs:subClassOf obo:CHEBI_50860 . obo:CHEBI_79008 obo:IAO_0000115 "The conjugate acid of (R)-nicotine arising from selective protonation of the tertiary amino group; major species at pH 7.3." ; chebi:charge "+1" ; chebi:formula "C10H15N2" ; chebi:inchi "InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/p+1/t10-/m1/s1" ; chebi:inchikey "SNICXCGAKADSCV-SNVBAGLBSA-O" ; chebi:mass "163.23900" ; chebi:monoisotopicmass "163.12297" ; chebi:smiles "C[NH+]1CCC[C@@H]1c1cccnc1" ; oboInOwl:hasDbXref "MetaCyc:R-NICOTINE" ; oboInOwl:hasExactSynonym "(2R)-1-methyl-2-(pyridin-3-yl)pyrrolidinium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(R)-nicotine" ; oboInOwl:id "CHEBI:79008" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(R)-nicotinium(1+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_39162 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_59806 ] . obo:CHEBI_79020 obo:IAO_0000115 "A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C#C bond." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2,3-unsaturated monocarboxylic acid", "2,3-unsaturated monocarboxylic acids", "alpha,beta-unsaturated monocarboxylic acids" ; oboInOwl:id "CHEBI:79020" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "alpha,beta-unsaturated monocarboxylic acid" ; rdfs:subClassOf obo:CHEBI_25384 . obo:CHEBI_79314 obo:IAO_0000115 "Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire." ; oboInOwl:hasDbXref "Wikipedia:Flame_retardant" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "flame retardants" ; oboInOwl:id "CHEBI:79314" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "flame retardant" ; rdfs:subClassOf obo:CHEBI_33232 . obo:CHEBI_79387 obo:IAO_0000115 "Any inorganic anion with a valency of three." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "trivalent inorganic anions" ; oboInOwl:id "CHEBI:79387" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "trivalent inorganic anion" ; rdfs:subClassOf obo:CHEBI_24834 . obo:CHEBI_79388 obo:IAO_0000115 "Any inorganic anion with a valency of two." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "divalent inorganic anions" ; oboInOwl:id "CHEBI:79388" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "divalent inorganic anion" ; rdfs:subClassOf obo:CHEBI_24834 . obo:CHEBI_79389 obo:IAO_0000115 "Any inorganic anion with a valency of one." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monovalent inorganic anions" ; oboInOwl:id "CHEBI:79389" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monovalent inorganic anion" ; rdfs:subClassOf obo:CHEBI_24834 . obo:CHEBI_8081 obo:IAO_0000115 "A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension." ; chebi:charge "0" ; chebi:formula "C17H19N3O" ; chebi:inchi "InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)" ; chebi:inchikey "MRBDMNSDAVCSSF-UHFFFAOYSA-N" ; chebi:mass "281.35230" ; chebi:monoisotopicmass "281.15281" ; chebi:smiles "Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1" ; oboInOwl:hasDbXref "CAS:50-60-2", "DrugBank:DB00692", "Drug_Central:2142", "HMDB:HMDB0014830", "KEGG:D00509", "KEGG:D08362", "LINCS:LSM-4022", "PMID:23438114", "PMID:23522530", "PMID:23658874", "PMID:23666670", "PMID:23887290", "PMID:23926134", "Patent:US2503059", "Reaxys:272944", "Wikipedia:Phentolamine" ; oboInOwl:hasExactSynonym "3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline", "Phentolamine mesylate", "Regitina", "Regitine", "Rogitine", "fentolamina", "phentolamine", "phentolaminum" ; oboInOwl:id "CHEBI:8081" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phentolamine" ; rdfs:subClassOf obo:CHEBI_24780, obo:CHEBI_33853, obo:CHEBI_48975, obo:CHEBI_50996, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35620 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_37890 ] . obo:CHEBI_8116 obo:IAO_0000115 "A diterpenoid with the structure of tigliane hydroxylated at C-4, -9, -12(beta), -13 and -20, with an oxo group at C-3 and unsaturation at the 1- and 6-positions." ; chebi:charge "0" ; chebi:formula "C20H28O6" ; chebi:inchi "InChI=1S/C20H28O6/c1-9-5-13-18(24,15(9)22)7-11(8-21)6-12-14-17(3,4)20(14,26)16(23)10(2)19(12,13)25/h5-6,10,12-14,16,21,23-26H,7-8H2,1-4H3/t10-,12+,13-,14-,16-,18-,19-,20-/m1/s1" ; chebi:inchikey "QGVLYPPODPLXMB-UBTYZVCOSA-N" ; chebi:mass "364.433" ; chebi:monoisotopicmass "364.18859" ; chebi:smiles "C=1[C@@]2([C@@]([C@]3([C@@](C(=O)C(=C3)C)(CC1CO)O)[H])([C@H](C)[C@H]([C@@]4([C@]2(C4(C)C)[H])O)O)O)[H]" ; oboInOwl:hasDbXref "Beilstein:2341335", "CAS:17673-25-5", "KEGG:C09155", "KNApSAcK:C00003465", "LIPID_MAPS_instance:LMPR0104330001", "PMID:27007853" ; oboInOwl:hasExactSynonym "(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-5H-cyclopropa[3,4]benzo[1,2-e]azulen-5-one", "Phorbol" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "4,9,12beta,13,20-pentahydroxy-1,6-tigliadien-3-on", "4,9,12beta,13,20-pentahydroxytiglia-1,6-dien-3-one" ; oboInOwl:id "CHEBI:8116" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "phorbol" ; rdfs:subClassOf obo:CHEBI_139592, obo:CHEBI_3992, obo:CHEBI_51689, obo:CHEBI_52557, [ a owl:Restriction ; owl:onProperty chebi5:has_parent_hydride ; owl:someValuesFrom obo:CHEBI_37526 ] . obo:CHEBI_82680 obo:IAO_0000115 "Any unsaturated fatty acid anion with one double or triple bond in the fatty acid chain." ; chebi:charge "-1" ; chebi:formula "CO2R" ; chebi:mass "44.010" ; chebi:monoisotopicmass "43.98983" ; chebi:smiles "[O-]C([*])=O" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "monounsaturated fatty acid anions" ; oboInOwl:id "CHEBI:82680" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "monounsaturated fatty acid anion" ; rdfs:subClassOf obo:CHEBI_2580, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_25413 ] . obo:CHEBI_82744 obo:IAO_0000115 "Any aldoxime derived from an aliphatic aldehyde." ; chebi:charge "0" ; chebi:formula "CH2NOR" ; chebi:mass "44.03270" ; chebi:monoisotopicmass "44.01364" ; chebi:smiles "ON=C[*]" ; oboInOwl:hasDbXref "MetaCyc:Aliphatic-Aldoximes" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "an aliphatic aldoxime" ; oboInOwl:id "CHEBI:82744" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "aliphatic aldoxime" ; rdfs:subClassOf obo:CHEBI_22307 . obo:CHEBI_83039 obo:IAO_0000115 "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "crustacean metabolites" ; oboInOwl:id "CHEBI:83039" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "crustacean metabolite" ; rdfs:subClassOf obo:CHEBI_75767 . obo:CHEBI_83056 obo:IAO_0000115 "A Daphnia metabolite produced by the species Daphnia magna." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Daphnia magna metabolites" ; oboInOwl:id "CHEBI:83056" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "Daphnia magna metabolite" ; rdfs:subClassOf obo:CHEBI_83057 . obo:CHEBI_83057 obo:IAO_0000115 "A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia" ; oboInOwl:hasDbXref "Wikipedia:Daphnia" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "Daphnia metabolites" ; oboInOwl:id "CHEBI:83057" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "Daphnia metabolite" ; rdfs:subClassOf obo:CHEBI_83039 . obo:CHEBI_83347 obo:IAO_0000115 "An ester resulting from the formal condensation of the hydroxy group of an alcohol, phenol, heteroarenol, or enol with an organosulfonic acid." ; chebi:charge "0" ; chebi:formula "O3SR2" ; chebi:mass "80.06300" ; chebi:monoisotopicmass "79.95681" ; chebi:smiles "[*]S(=O)(=O)O[*]" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "organosulfonate ester", "organosulfonate esters", "organosulfonic esters" ; oboInOwl:id "CHEBI:83347" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "organosulfonic ester" ; rdfs:subClassOf obo:CHEBI_33424, obo:CHEBI_35701, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_33551 ] . obo:CHEBI_83399 obo:IAO_0000115 "Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "marine xenobiotic metabolites" ; oboInOwl:id "CHEBI:83399" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "marine xenobiotic metabolite" ; rdfs:subClassOf obo:CHEBI_76206, obo:CHEBI_76507 . obo:CHEBI_83565 obo:IAO_0000115 "An organofluorine compound that is (trifluoromethyl)benzene and derivatives arising from substitution of one or more of the phenyl hydrogens." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:83565" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(trifluoromethyl)benzenes" ; rdfs:subClassOf obo:CHEBI_22712, obo:CHEBI_37143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:CHEBI_50127 ] . obo:CHEBI_83811 obo:IAO_0000115 "Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical amino acid derivative", "canonical amino acid derivatives", "canonical amino-acid derivative", "canonical amino-acid derivatives", "proteinogenic amino acid derivatives", "proteinogenic amino-acid derivative", "proteinogenic amino-acid derivatives" ; oboInOwl:id "CHEBI:83811" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "proteinogenic amino acid derivative" ; rdfs:subClassOf obo:CHEBI_83821, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_83813 ] . obo:CHEBI_83813 obo:IAO_0000115 "Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration." ; oboInOwl:hasDbXref "Wikipedia:Proteinogenic_amino_acid" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "canonical amino acid", "canonical amino acids", "proteinogenic amino acids" ; oboInOwl:id "CHEBI:83813" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "proteinogenic amino acid" ; rdfs:subClassOf obo:CHEBI_33709 . obo:CHEBI_83820 obo:IAO_0000115 "Any amino-acid that is not naturally encoded in the genetic code of any organism." ; oboInOwl:hasDbXref "Wikipedia:Non-proteinogenic_amino_acids" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "non-canonical amino acid", "non-canonical amino acids", "non-canonical amino-acid", "non-canonical amino-acids", "non-coded amino acid", "non-coded amino acids", "non-coded amino-acid", "non-coded amino-acids", "non-proteinogenic amino acids", "non-proteinogenic amino-acid", "non-proteinogenic amino-acids" ; oboInOwl:id "CHEBI:83820" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "non-proteinogenic amino acid" ; rdfs:subClassOf obo:CHEBI_33709 . obo:CHEBI_83821 obo:IAO_0000115 "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues." ; oboInOwl:hasAlternativeId "CHEBI:25359" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "amino acid derivatives", "modified amino acids" ; oboInOwl:id "CHEBI:83821" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "amino acid derivative" ; rdfs:subClassOf obo:CHEBI_35352 . obo:CHEBI_83824 obo:IAO_0000115 "A proteinogenic amino acid derivative resulting from the formal reaction of L-cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of L-cysteine by a heteroatom." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "L-cysteine derivatives" ; oboInOwl:id "CHEBI:83824" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "L-cysteine derivative" ; rdfs:subClassOf obo:CHEBI_23509, obo:CHEBI_83811, [ a owl:Restriction ; owl:onProperty chebi5:has_functional_parent ; owl:someValuesFrom obo:CHEBI_17561 ] . obo:CHEBI_83925 obo:IAO_0000115 "Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "non-proteinogenic alpha-amino acids", "non-proteinogenic alpha-amino-acid", "non-proteinogenic alpha-amino-acids" ; oboInOwl:id "CHEBI:83925" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "non-proteinogenic alpha-amino acid" ; rdfs:subClassOf obo:CHEBI_33704, obo:CHEBI_83820 . obo:CHEBI_83970 obo:IAO_0000115 "Steroid lactones containing sugar residues that act on the contractile force of the cardiac muscles." ; oboInOwl:hasDbXref "Wikipedia:Cardiac_glycoside" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "cardiac glycosides" ; oboInOwl:id "CHEBI:83970" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "cardiac glycoside" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_24400, obo:CHEBI_26766, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_77307 ] . obo:CHEBI_84055 obo:IAO_0000115 "Any phospho sugar that is the phosphate derivative of pentose." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "pentose phosphates" ; oboInOwl:id "CHEBI:84055" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "pentose phosphate" ; rdfs:subClassOf obo:CHEBI_33447, obo:CHEBI_63409 . obo:CHEBI_84087 obo:IAO_0000115 "Any metabolite (endogenous or exogenous) found in human urine samples." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "human urinary metabolites" ; oboInOwl:id "CHEBI:84087" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "human urinary metabolite" ; rdfs:subClassOf obo:CHEBI_77746 . obo:CHEBI_84729 obo:IAO_0000115 "Any member of the class of indoles carrying at least one hydroxy group." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:84729" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "hydroxyindoles" ; rdfs:subClassOf obo:CHEBI_24828, obo:CHEBI_33822 . obo:CHEBI_84735 obo:IAO_0000115 "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "algal metabolites" ; oboInOwl:id "CHEBI:84735" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "algal metabolite" ; rdfs:subClassOf obo:CHEBI_75763 . obo:CHEBI_85046 obo:IAO_0000115 "Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin." ; oboInOwl:hasDbXref "PMID:21265866", "PMID:22132817", "PMID:22314516", "PMID:23891889", "PMID:23974587", "PMID:25535470", "PMID:25574195", "PMID:25643794", "Wikipedia:Skin_whitening" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "melanogenesis inhibitor", "melanogenesis inhibitors", "skin bleaching agent", "skin bleaching agents", "skin depigmenting agent", "skin depigmenting agents", "skin lightening agents", "skin whitening agent", "skin whitening agents" ; oboInOwl:id "CHEBI:85046" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "skin lightening agent" ; rdfs:subClassOf obo:CHEBI_64857 . obo:CHEBI_85234 obo:IAO_0000115 "Any metabolite (endogenous or exogenous) found in human blood serum samples." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "human blood serum metabolites" ; oboInOwl:id "CHEBI:85234" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "human blood serum metabolite" ; rdfs:subClassOf obo:CHEBI_77746 . obo:CHEBI_86315 obo:IAO_0000115 "Any aliphatic sulfide in which at least one of the organyl groups attached to the sulfur is a methyl group." ; chebi:charge "0" ; chebi:formula "CH3SR" ; chebi:mass "47.101" ; chebi:monoisotopicmass "46.99555" ; chebi:smiles "CS[*]" ; oboInOwl:hasAlternativeId "CHEBI:25260" ; oboInOwl:hasDbXref "MetaCyc:Methyl-thioethers" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "a methyl thioether", "methyl sulfides", "methyl thioether", "methyl thioethers" ; oboInOwl:id "CHEBI:86315" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "methyl sulfide" ; rdfs:subClassOf obo:CHEBI_16385 . obo:CHEBI_86990 obo:IAO_0000115 "An aromatic ether consisting of 4-trifluoromethylphenol in which the hydrogen of the phenolic hydroxy group is replaced by a 3-(methylamino)-1-phenylpropyl group." ; chebi:charge "0" ; chebi:formula "C17H18F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3" ; chebi:inchikey "RTHCYVBBDHJXIQ-UHFFFAOYSA-N" ; chebi:mass "309.32610" ; chebi:monoisotopicmass "309.13405" ; chebi:smiles "CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "LINCS:LSM-1449", "VSDB:1851" ; oboInOwl:hasExactSynonym "N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "CHEBI:86990" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; rdfs:subClassOf obo:CHEBI_35618, obo:CHEBI_50995, obo:CHEBI_83565 . obo:CHEBI_86991 obo:IAO_0000115 "An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has R configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine]." ; chebi:charge "0" ; chebi:formula "C17H18F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/t16-/m1/s1" ; chebi:inchikey "RTHCYVBBDHJXIQ-MRXNPFEDSA-N" ; chebi:mass "309.32610" ; chebi:monoisotopicmass "309.13405" ; chebi:smiles "CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "CAS:100568-03-4", "PMID:19144769", "PMID:19788198", "PMID:20663810", "PMID:22903652", "PMID:22923967", "PMID:23885544", "PMID:24464553", "PMID:24997906", "Reaxys:4356432" ; oboInOwl:hasExactSynonym "(3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-fluoxetine", "(R)-(+)-fluoxetine", "(R)-N-methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine", "(R)-N-methyl-3-(4-trifluoromethylphenyloxy)-3-(phenyl)propylamine", "(R)-N-methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy]propylamine", "(R)-N-methyl-gamma-(4-trifluoromethylphenoxy)-3-phenylpropylamine", "(R)-Prozac" ; oboInOwl:id "CHEBI:86991" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(R)-fluoxetine" ; rdfs:subClassOf obo:CHEBI_86990, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50949 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_86993 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_86992 ] . obo:CHEBI_86992 obo:IAO_0000115 "An N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine that has S configuration. [The antidepressant drug fluoxetine is a racemate comprising equimolar amounts of (R)- and (S)-fluoxetine]." ; chebi:charge "0" ; chebi:formula "C17H18F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/t16-/m0/s1" ; chebi:inchikey "RTHCYVBBDHJXIQ-INIZCTEOSA-N" ; chebi:mass "309.32610" ; chebi:monoisotopicmass "309.13405" ; chebi:smiles "CNCC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "PMID:19144769", "PMID:19788198", "PMID:20663810", "PMID:22903652", "PMID:22923967", "PMID:23885544", "PMID:24464553", "PMID:24997906", "Reaxys:4356433" ; oboInOwl:hasExactSynonym "(3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-fluoxetine", "(S)-(-)-fluoxetine", "(S)-N-methyl-3-(4-trifluoromethylphenoxy)-3-phenylpropylamine", "(S)-N-methyl-3-(4-trifluoromethylphenyloxy)-3-(phenyl)propylamine", "(S)-N-methyl-3-phenyl-3-[(alpha,alpha,alpha-trifluoro-p-tolyl)oxy]propylamine", "(S)-N-methyl-gamma-(4-trifluoromethylphenoxy)-3-phenylpropylamine", "(S)-Prozac" ; oboInOwl:id "CHEBI:86992" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(S)-fluoxetine" ; rdfs:subClassOf obo:CHEBI_86990, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35469 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50949 ], [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_base_of ; owl:someValuesFrom obo:CHEBI_86995 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_86991 ] . obo:CHEBI_86993 obo:IAO_0000115 "An organic cation resulting from the protonation of the amino group of (R)-fluoxetine." ; chebi:charge "+1" ; chebi:formula "C17H19F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/p+1/t16-/m1/s1" ; chebi:inchikey "RTHCYVBBDHJXIQ-MRXNPFEDSA-O" ; chebi:mass "310.33350" ; chebi:monoisotopicmass "310.14133" ; chebi:smiles "C[NH2+]CC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "Reaxys:25263171" ; oboInOwl:hasExactSynonym "(3R)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(+)-fluoxetine(1+)" ; oboInOwl:id "CHEBI:86993" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(R)-fluoxetine(1+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_86991 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_86995 ] . obo:CHEBI_86995 obo:IAO_0000115 "An organic cation resulting from the protonation of the amino group of (S)-fluoxetine." ; chebi:charge "+1" ; chebi:formula "C17H19F3NO" ; chebi:inchi "InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3/p+1/t16-/m0/s1" ; chebi:inchikey "RTHCYVBBDHJXIQ-INIZCTEOSA-O" ; chebi:mass "310.33350" ; chebi:monoisotopicmass "310.14133" ; chebi:smiles "C[NH2+]CC[C@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1" ; oboInOwl:hasDbXref "Reaxys:25263174" ; oboInOwl:hasExactSynonym "(3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-aminium" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "(-)-fluoxetine(1+)" ; oboInOwl:id "CHEBI:86995" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "(S)-fluoxetine(1+)" ; rdfs:subClassOf obo:CHEBI_25697, obo:CHEBI_35274, [ a owl:Restriction ; owl:onProperty chebi5:is_conjugate_acid_of ; owl:someValuesFrom obo:CHEBI_86992 ], [ a owl:Restriction ; owl:onProperty chebi5:is_enantiomer_of ; owl:someValuesFrom obo:CHEBI_86993 ] . obo:CHEBI_88184 obo:IAO_0000115 "Any metal which causes the onset of an allergic reaction." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "allergenic metal", "allergenic metals", "metal allergens" ; oboInOwl:id "CHEBI:88184" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "metal allergen" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_33521, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_50904 ] . obo:CHEBI_88188 obo:IAO_0000115 "Any drug which causes the onset of an allergic reaction." ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "allergenic drug" ; oboInOwl:id "CHEBI:88188" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "drug allergen" ; rdfs:subClassOf obo:CHEBI_23888, obo:CHEBI_50904 . obo:CHEBI_88230 obo:IAO_0000115 "Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell)." ; oboInOwl:hasDbXref "PMID:24830781", "PMID:25727221", "PMID:25793774", "PMID:25896709", "Wikipedia:Autophagy" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "autophagocytosis inhibitor", "autophagocytosis inhibitors", "autophagy inhibitors" ; oboInOwl:id "CHEBI:88230" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "autophagy inhibitor" ; rdfs:subClassOf obo:CHEBI_35222, obo:CHEBI_52206 . obo:CHEBI_90710 obo:IAO_0000115 "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors." ; oboInOwl:hasAlternativeId "CHEBI:189678" ; oboInOwl:hasDbXref "Wikipedia:Receptor_modulator" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "receptor modulators" ; oboInOwl:id "CHEBI:90710" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "receptor modulator" ; rdfs:subClassOf obo:CHEBI_23888 . obo:CHEBI_9727 obo:IAO_0000115 "An oxazolidinone that is 1,3-oxazolidine-2,4-dione substituted by methyl groups at positions 3, 5 and 5. It is an antiepileptic agent." ; chebi:charge "0" ; chebi:formula "C6H9NO3" ; chebi:inchi "InChI=1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3" ; chebi:inchikey "IRYJRGCIQBGHIV-UHFFFAOYSA-N" ; chebi:mass "143.142" ; chebi:monoisotopicmass "143.05824" ; chebi:smiles "CN1C(=O)OC(C)(C)C1=O" ; oboInOwl:hasAlternativeId "CHEBI:94526" ; oboInOwl:hasDbXref "CAS:127-48-0", "DrugBank:DB00347", "Drug_Central:2751", "HMDB:HMDB0014491", "KEGG:D00392", "LINCS:LSM-5345", "PMID:10634315", "PMID:11057156", "PMID:11722678", "PMID:13590839", "PMID:13649111", "PMID:15282739", "PMID:15653505", "PMID:16171802", "PMID:18248662", "PMID:18862627", "PMID:18876072", "PMID:21638752", "PMID:2210093", "PMID:23017458", "PMID:23321016", "PMID:30605901", "PMID:7653500", "PMID:8791774", "PMID:8865369", "PMID:9375358", "PMID:9827046", "Reaxys:121627", "Wikipedia:Trimethadione" ; oboInOwl:hasExactSynonym "3,5,5-trimethyl-1,3-oxazolidine-2,4-dione" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:hasRelatedSynonym "3,5,5-trimethyl-2,4-oxazolidinedione", "Absentol", "Absetil", "Convenixa", "Edion", "Epidione", "Epixal", "Petidion", "Petilep", "Petimalin", "Ptimal", "Tridione", "Tridione Dulcet", "trimetadiona", "trimetadione", "trimethadione", "trimethadionum" ; oboInOwl:id "CHEBI:9727" ; oboInOwl:inSubset chebi3:_STAR ; a owl:Class ; rdfs:label "trimethadione" ; rdfs:subClassOf obo:BFO_0000004, obo:CHEBI_55374, [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_176497 ], [ a owl:Restriction ; owl:onProperty obo:RO_0000087 ; owl:someValuesFrom obo:CHEBI_35623 ] . obo:CL_0000000 obo:IAO_0000115 "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane." ; oboInOwl:hasDbXref "CALOHA:TS-2035", "FBbt:00007002", "FMA:68646", "GO:0005623", "KUPO:0000002", "MESH:D002477", "VHOG:0001533", "WBbt:0004017", "XAO:0003012" ; oboInOwl:inSubset ubprop:_upper_level ; a owl:Class ; rdfs:comment "The definition of cell is intended to represent all cells, and thus a cell is defined as a material entity and not an anatomical structure, which implies that it is part of an organism (or the entirety of one)." ; rdfs:label "cell" ; rdfs:subClassOf obo:UBERON_0000061, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_131567 ] . obo:CL_0000007 obo:IAO_0000115 "A cell found in the embryo before the formation of all the gem layers is complete." ; a owl:Class ; rdfs:label "early embryonic cell (metazoa)" ; rdfs:subClassOf obo:CL_0002321 . obo:CL_0000021 obo:IAO_0000115 "Female germ cell is a germ cell that supports female gamete production." ; oboInOwl:hasDbXref "MA:0000388", "VHOG:0001530", "ncithesaurus:Egg" ; a owl:Class ; rdfs:label "female germ cell" ; rdfs:subClassOf obo:CL_0000586, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048477 ] ) ] . obo:CL_0000023 obo:IAO_0000115 "A female germ cell that has entered meiosis." ; oboInOwl:hasDbXref "BTO:0000964", "CALOHA:TS-0711", "FBbt:00004886", "FMA:18644", "MESH:D009865", "WBbt:0006797" ; oboInOwl:hasRelatedSynonym "oogonium" ; a owl:Class ; rdfs:label "oocyte" ; rdfs:subClassOf obo:CL_0000021, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:GO_0007143 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ] . obo:CL_0000024 obo:IAO_0000115 "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes." ; oboInOwl:hasDbXref "FMA:83673" ; a owl:Class ; rdfs:label "oogonial cell" ; rdfs:subClassOf obo:CL_0000021, [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000670 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000021 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:CL_0000025 obo:IAO_0000115 "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization." ; oboInOwl:hasDbXref "BTO:0000369", "BTO:0003801", "CALOHA:TS-2191", "FBbt:00057012", "FMA:67343", "MESH:D010063" ; oboInOwl:hasExactSynonym "mature oocyte", "ovum" ; a owl:Class ; rdfs:label "egg cell" ; rdfs:subClassOf obo:CL_0000675, [ a owl:Restriction ; owl:onProperty obo:RO_0000056 ; owl:someValuesFrom obo:GO_0007143 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002202 ; owl:someValuesFrom obo:CL_0000023 ] ; foaf:depiction "https://www.swissbiopics.org/api/image/Egg_cell.svg"^^xsd:anyURI . obo:CL_0000039 obo:IAO_0000115 "A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring." ; oboInOwl:inSubset cl:general_cell_types_upper_slim, ubprop:_upper_level ; a owl:Class ; rdfs:comment "Originally this term had some plant germ line cell children." ; rdfs:label "germ line cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0022414 ] . obo:CL_0000064 obo:IAO_0000115 "A cell that has a filiform extrusion of the cell surface." ; oboInOwl:hasDbXref "VHOG:0001532", "XAO:0000031" ; a owl:Class ; rdfs:label "ciliated cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005929 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:CL_0000066 obo:IAO_0000115 "A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000414", "CALOHA:TS-2026", "CARO:0000077", "FBbt:00000124", "FMA:66768", "WBbt:0003672" ; oboInOwl:hasExactSynonym "epitheliocyte" ; oboInOwl:inSubset cl:general_cell_types_upper_slim, core:human_reference_atlas ; a owl:Class ; rdfs:label "epithelial cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000483 ] ; foaf:depiction "https://www.swissbiopics.org/api/image/Epithelial_cells.svg"^^xsd:anyURI . obo:CL_0000067 obo:IAO_0000115 "An epithelial cell that has a cilia." ; oboInOwl:hasDbXref "FMA:70605" ; a owl:Class ; rdfs:label "ciliated epithelial cell" ; rdfs:subClassOf obo:CL_0000064, obo:CL_0000066 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:CL_0000075 obo:IAO_0000115 "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "columnar/cuboidal epithelial cell" ; rdfs:subClassOf obo:CL_0000066 . obo:CL_0000076 oboInOwl:hasDbXref "CALOHA:TS-1249" ; a owl:Class ; rdfs:label "squamous epithelial cell" ; rdfs:subClassOf obo:CL_0000066 . obo:CL_0000082 obo:IAO_0000115 "An epithelial cell of the lung." ; oboInOwl:hasDbXref "BTO:0004299" ; oboInOwl:hasExactSynonym "lung epithelial cell" ; a owl:Class ; rdfs:label "epithelial cell of lung" ; rdfs:subClassOf obo:CL_0000066, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000115 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000066 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_0000086 obo:IAO_0000233 "https://github.com/obophenotype/cell-ontology/issues/1935" ; obo:IAO_0100001 obo:CL_0000014 ; a owl:Class ; rdfs:comment "Obsoleted as there is no need for a term specific for nematods and protostomes." ; rdfs:label "obsolete germ line stem cell (sensu Nematoda and Protostomia)" ; owl:deprecated true . obo:CL_0000151 obo:IAO_0000115 "A cell that specializes in controlled release of one or more substances." ; oboInOwl:hasDbXref "BTO:0003659", "FMA:86916" ; a owl:Class ; rdfs:label "secretory cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0032940 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0032940 ] ) ] . obo:CL_0000154 a owl:Class ; rdfs:label "protein secreting cell" ; rdfs:subClassOf obo:CL_0000151, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009306 ] ) ] . obo:CL_0000211 obo:IAO_0000115 "A cell whose function is determined by the generation or the reception of an electric signal." ; a owl:Class ; rdfs:label "electrically active cell" ; rdfs:subClassOf obo:CL_0000000 . obo:CL_0000219 obo:IAO_0000115 "A cell that moves by its own activities." ; a owl:Class ; rdfs:label "motile cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048870 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048870 ] ) ] . obo:CL_0000228 obo:IAO_0000115 "A cell with more than one nucleus." ; oboInOwl:hasDbXref "AEO:0000203", "WBbt:0008074" ; oboInOwl:hasExactSynonym "syncitium", "syncytial cell", "syncytium" ; a owl:Class ; rdfs:label "multinucleate cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001908 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001908 ] ) ] . obo:CL_0000300 obo:IAO_0000115 "A mature sexual reproductive cell having a single set of unpaired chromosomes." ; oboInOwl:hasDbXref "CALOHA:TS-0395", "FBbt:00005412", "FMA:18649" ; oboInOwl:hasExactSynonym "haploid nucleated cell" ; oboInOwl:hasRelatedSynonym "haploid germ cell" ; a owl:Class ; rdfs:label "gamete" ; rdfs:subClassOf obo:CL_0000413, obo:CL_0000586, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001375 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0009566 ] ) ] . obo:CL_0000365 obo:IAO_0000115 "Diploid cell produced by the fusion of sperm cell nucleus and egg cell." ; oboInOwl:hasBroadSynonym "zygote" ; oboInOwl:hasDbXref "BTO:0000854", "EHDAA2:0004546", "FMA:72395" ; a owl:Class ; rdfs:label "animal zygote" ; rdfs:subClassOf obo:CL_0000007, obo:CL_0010017, [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0010017 [ a owl:Restriction ; owl:onProperty obo:RO_0002160 ; owl:someValuesFrom obo:NCBITaxon_33208 ] ) ] . obo:CL_0000393 obo:IAO_0000115 "A cell whose function is determined by its response to an electric signal." ; a owl:Class ; rdfs:label "electrically responsive cell" ; rdfs:subClassOf obo:CL_0000211 . obo:CL_0000404 obo:IAO_0000115 "A cell that initiates an electrical signal and passes that signal to another cell." ; a owl:Class ; rdfs:label "electrically signaling cell" ; rdfs:subClassOf obo:CL_0000211 . obo:CL_0000411 obo:IAO_0000115 "An epithelial cell of the hypodermis of Caenorhabditis." ; oboInOwl:hasBroadSynonym "roundworm hypodermal cell" ; oboInOwl:hasDbXref "WBbt:0007846" ; a owl:Class ; rdfs:comment "This term was originally added to CL for parity with the Worm anatomy ontology, which is dedicated to C elegans. It is not clear if it makes sense to try and generalize the concept and include in CL, and this term may be obsoleted in future. Note there is no similarity to the hypodermis in vertebrates." ; rdfs:label "Caenorhabditis hypodermal cell" ; rdfs:subClassOf obo:CL_0000076, obo:CL_0000228, [ a owl:Restriction ; owl:onProperty obo:RO_0002162 ; owl:someValuesFrom obo:NCBITaxon_6237 ] . obo:CL_0000413 obo:IAO_0000115 "A cell whose nucleus contains a single haploid genome." ; a owl:Class ; rdfs:label "haploid cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001375 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0001375 ] ) ] . obo:CL_0000540 obo:IAO_0000115 "The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." ; obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:hasDbXref "BTO:0000938", "CALOHA:TS-0683", "FBbt:00005106", "FMA:54527", "VHOG:0001483", "WBbt:0003679" ; oboInOwl:hasExactSynonym "nerve cell" ; oboInOwl:inSubset cl:general_cell_types_upper_slim, core:human_reference_atlas ; a owl:Class ; rdfs:comment "These cells are also reportedly CD4-negative and CD200-positive. They are also capable of producing CD40L and IFN-gamma." ; rdfs:label "neuron" ; rdfs:subClassOf obo:CL_0000393, obo:CL_0000404, obo:CL_0002319, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0019226 ] ; foaf:depiction "https://www.swissbiopics.org/api/image/Neuron_cells.svg"^^xsd:anyURI . obo:CL_0000586 obo:IAO_0000115 "The reproductive cell in multicellular organisms." ; oboInOwl:hasDbXref "BTO:0000535", "NCIT:C12597", "VHOG:0001534", "WBbt:0006796" ; a owl:Class ; rdfs:label "germ cell" ; rdfs:subClassOf obo:CL_0000039, [ a owl:Restriction ; owl:onProperty obo:RO_0002216 ; owl:someValuesFrom obo:GO_0009566 ] . obo:CL_0000618 a owl:Class ; rdfs:label "sheath cell" ; rdfs:subClassOf obo:CL_0000075 . obo:CL_0000670 obo:IAO_0000115 "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells." ; oboInOwl:hasDbXref "FMA:70567" ; oboInOwl:hasExactSynonym "gonocyte", "primitive germ cell" ; a owl:Class ; rdfs:label "primordial germ cell" ; rdfs:subClassOf obo:CL_0000039, obo:CL_0000219, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000922 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000039 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0000922 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0048870 ] ) ] . obo:CL_0000675 obo:IAO_0000115 "A mature sexual reproductive cell of the female germline." ; a owl:Class ; rdfs:label "female gamete" ; rdfs:subClassOf obo:CL_0000021, obo:CL_0000300 . obo:CL_0001061 obo:IAO_0000115 "A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models." ; terms:contributor ; terms:date "2017-01-30T18:53:32Z"^^xsd:dateTime ; oboInOwl:hasDbXref "https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C12913" ; a owl:Class ; rdfs:comment "https://github.com/obophenotype/cell-ontology/issues/448" ; rdfs:label "abnormal cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000460 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] . obo:CL_0002319 obo:IAO_0000115 "A cell that is part of the nervous system." ; terms:contributor ; oboInOwl:creation_date "2010-09-15T01:34:57Z" ; oboInOwl:hasDbXref "CALOHA:TS-2040", "FMA:70333" ; a owl:Class ; rdfs:label "neural cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001016 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001016 ] ) ] . obo:CL_0002321 obo:IAO_0000115 "A cell of the embryo." ; terms:contributor ; oboInOwl:creation_date "2010-09-15T03:39:21Z" ; oboInOwl:hasDbXref "CALOHA:TS-0263", "FMA:82840", "WBbt:0007028" ; a owl:Class ; rdfs:label "embryonic cell (metazoa)" ; rdfs:subClassOf obo:CL_0000000 . obo:CL_0002371 obo:IAO_0000115 "OBSOLETE. A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell)." ; obo:IAO_0100001 obo:CL_0000000 ; terms:contributor ; oboInOwl:creation_date "2010-09-24T09:44:42Z" ; oboInOwl:hasDbXref "BTO:0001268", "FMA:72300", "WBbt:0008378" ; oboInOwl:inSubset ubprop:_upper_level ; a owl:Class ; rdfs:comment "https://github.com/obophenotype/cell-ontology/issues/1150" ; rdfs:label "obsolete somatic cell" ; owl:deprecated true . obo:CL_0010017 obo:IAO_0000115 "A zygote in a plant or an animal." ; oboInOwl:hasDbXref "MESH:D015053" ; a owl:Class ; rdfs:label "zygote"@en ; rdfs:seeAlso ; rdfs:subClassOf obo:CL_0000000 . obo:CL_0011115 obo:IAO_0000115 "A cell that, by division or terminal differentiation, can give rise to other cell types." ; a owl:Class ; rdfs:comment "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell." ; rdfs:label "precursor cell" ; rdfs:subClassOf obo:CL_0000000, [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000000 [ a owl:Restriction ; owl:onProperty obo:RO_0002215 ; owl:someValuesFrom obo:GO_0030154 ] ) ] . obo:CL_0017505 obo:IAO_0000115 "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell." ; terms:contributor ; oboInOwl:creation_date "2009-12-23T10:53:24Z" ; a owl:Class ; rdfs:label "increased nucleus size" ; rdfs:subClassOf obo:GO_0005634, [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000586 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005634 [ a owl:Restriction ; owl:onProperty obo:RO_0000053 ; owl:someValuesFrom obo:PATO_0000586 ] ) ] . obo:CL_1000271 obo:RO_0002175 obo:NCBITaxon_9606 ; oboInOwl:inSubset core:human_reference_atlas ; a owl:Class ; rdfs:label "lung ciliated cell" ; rdfs:subClassOf obo:CL_4030034, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000064 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_1000272 a owl:Class ; rdfs:label "lung secretory cell" ; rdfs:subClassOf obo:CL_0000151, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000151 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0002048 ] ) ] . obo:CL_4030034 obo:IAO_0000115 "A ciliated cell of the respiratory system. Ciliated cells are present in airway epithelium." ; terms:date "2023-01-25T11:06:01Z"^^xsd:dateTime ; oboInOwl:hasExactSynonym "ciliated cell of the respiratory tract" ; a owl:Class ; rdfs:label "respiratory ciliated cell" ; rdfs:subClassOf obo:CL_0000064, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0001004 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004802 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:CL_0000064 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:UBERON_0004802 ] ) ] . obo:GO_0000002 obo:IAO_0000115 "The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000002" ; a owl:Class ; rdfs:label "mitochondrial genome maintenance" ; rdfs:subClassOf obo:GO_0007005 . obo:GO_0000003 obo:IAO_0000115 "The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms." ; oboInOwl:hasAlternativeId "GO:0019952", "GO:0050876" ; oboInOwl:hasDbXref "Wikipedia:Reproduction" ; oboInOwl:hasExactSynonym "reproductive physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000003" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "reproduction" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0000018 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000018" ; a owl:Class ; rdfs:label "regulation of DNA recombination" ; rdfs:subClassOf obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006310 ] ) ] . obo:GO_0000022 obo:IAO_0000115 "The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-04-08T15:06:14Z" ; oboInOwl:hasAlternativeId "GO:1905121" ; oboInOwl:hasExactSynonym "spindle elongation during mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microtubule sliding involved in mitotic spindle elongation" ; oboInOwl:id "GO:0000022" ; a owl:Class ; rdfs:label "mitotic spindle elongation" ; rdfs:subClassOf obo:GO_0051231, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051231 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000070 obo:IAO_0000115 "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets." ; oboInOwl:hasAlternativeId "GO:0016359" ; oboInOwl:hasExactSynonym "mitotic chromosome segregation" ; oboInOwl:hasNarrowSynonym "mitotic sister-chromatid adhesion release" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000070" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "mitotic sister chromatid segregation" ; rdfs:subClassOf obo:GO_0000819, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098813 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0000075 obo:IAO_0000115 "A signaling process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0031576", "GO:0071779", "GO:0072395", "GO:0072404", "GO:0072407" ; oboInOwl:hasDbXref "Wikipedia:Cell_cycle_checkpoint" ; oboInOwl:hasExactSynonym "cell cycle checkpoint", "signal transduction involved in G2/M transition checkpoint", "signal transduction involved in cell cycle checkpoint" ; oboInOwl:hasNarrowSynonym "G1/S checkpoint", "G1/S transition checkpoint", "G2/M checkpoint", "G2/M transition checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000075" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "This term should not be used in direct manual annotation as it should always be possible to minimally designate mitotic or meiotic checkpoint, and usually to additionally specify the checkpoint (i.e mitotic spindle assembly checkpoint, mitotic DNA damage checkpoint etc). Note also that the effector processes are not part of the checkpoint but are positively regulated by the checkpoint signaling and should not be annotated here." ; rdfs:label "cell cycle checkpoint signaling" ; rdfs:subClassOf obo:GO_0035556, obo:GO_1901988 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0035556 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044770 ] ) ] . obo:GO_0000077 obo:IAO_0000115 "A signal transduction process that contributes to a DNA damage checkpoint." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-12-08T04:18:11Z" ; oboInOwl:hasAlternativeId "GO:0072422" ; oboInOwl:hasDbXref "Wikipedia:DNA_damage_checkpoint", "Wikipedia:Postreplication_checkpoint" ; oboInOwl:hasExactSynonym "DNA damage checkpoint", "signal transduction involved in DNA damage checkpoint" ; oboInOwl:hasNarrowSynonym "DNA damage response, signal transduction resulting in cell cycle arrest" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000077" ; a owl:Class ; rdfs:label "DNA damage checkpoint signaling" ; rdfs:subClassOf obo:GO_0031570, obo:GO_0042770 . obo:GO_0000082 obo:IAO_0000115 "The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000082" ; a owl:Class ; rdfs:label "G1/S transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0044772, obo:GO_0044843 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044843 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000084 obo:IAO_0000115 "The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle." ; oboInOwl:hasExactSynonym "S phase of mitotic cell cycle", "S-phase of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000084" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "mitotic S phase" ; rdfs:subClassOf obo:GO_0051320, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051329 ] . obo:GO_0000086 obo:IAO_0000115 "The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex." ; oboInOwl:hasExactSynonym "mitotic G2/M transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000086" ; a owl:Class ; rdfs:label "G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0044772, obo:GO_0044839 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044839 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000087 obo:IAO_0000115 "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle." ; oboInOwl:hasExactSynonym "M phase of mitotic cell cycle", "M-phase of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000087" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "mitotic M phase" ; rdfs:subClassOf obo:GO_0000279, obo:GO_0098763 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000279 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000132 obo:IAO_0000115 "A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures." ; oboInOwl:hasAlternativeId "GO:0030607", "GO:0030609" ; oboInOwl:hasExactSynonym "establishment of spindle orientation involved in mitotic cell cycle", "mitotic spindle orientation", "orienting of mitotic spindle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "establishment of spindle orientation during mitosis" ; oboInOwl:id "GO:0000132" ; a owl:Class ; rdfs:label "establishment of mitotic spindle orientation" ; rdfs:subClassOf obo:GO_0040001, obo:GO_0051294 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051294 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000184 obo:IAO_0000115 "The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins." ; oboInOwl:hasDbXref "Wikipedia:Nonsense-mediated_decay", "Wikipedia:Nonsense-mediated_mRNA_decay" ; oboInOwl:hasExactSynonym "mRNA breakdown, nonsense-mediated decay", "mRNA catabolic process, nonsense-mediated", "mRNA catabolism, nonsense-mediated", "mRNA degradation, nonsense-mediated decay", "nonsense-mediated mRNA decay", "nuclear mRNA catabolic process, nonsense-mediated decay" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000184" ; a owl:Class ; rdfs:label "nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ; rdfs:subClassOf obo:GO_0000956 . obo:GO_0000212 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle." ; oboInOwl:hasAlternativeId "GO:0043147" ; oboInOwl:hasExactSynonym "meiotic spindle organisation", "spindle organization during meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiotic spindle organization and biogenesis", "meiotic spindle stabilization" ; oboInOwl:id "GO:0000212" ; a owl:Class ; rdfs:label "meiotic spindle organization" ; rdfs:subClassOf obo:GO_0007051, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007051 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0000226 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23114"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/23195"^^xsd:anyURI ; oboInOwl:hasExactSynonym "microtubule cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microtubule cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0000226" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "microtubule cytoskeleton organization" ; rdfs:subClassOf obo:GO_0007010, obo:GO_0007017 . obo:GO_0000228 obo:IAO_0000115 "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact." ; oboInOwl:hasNarrowSynonym "nuclear interphase chromosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0000228" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic ; a owl:Class ; rdfs:label "nuclear chromosome" ; rdfs:subClassOf obo:GO_0005694, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031981 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005694 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0000235 obo:IAO_0000115 "Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0000235" ; a owl:Class ; rdfs:label "astral microtubule" ; rdfs:subClassOf obo:GO_0005876, obo:GO_0005881, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005818 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005876 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005818 ] ) ] . obo:GO_0000262 obo:IAO_0000115 "A chromosome found in the mitochondrion of a eukaryotic cell." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1186327184" ; oboInOwl:hasNarrowSynonym "mitochondrial DNA", "mtDNA" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "mitochondrial genome" ; oboInOwl:id "GO:0000262" ; a owl:Class ; rdfs:label "mitochondrial chromosome" ; rdfs:subClassOf obo:GO_0005694, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042645 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005694 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0000278 obo:IAO_0000115 "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." ; oboInOwl:hasAlternativeId "GO:0007067" ; oboInOwl:hasDbXref "Wikipedia:Mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitosis" ; oboInOwl:id "GO:0000278" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle." ; rdfs:label "mitotic cell cycle" ; rdfs:subClassOf obo:GO_0007049, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007049 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0000279 obo:IAO_0000115 "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase." ; oboInOwl:hasDbXref "Wikipedia:M_phase" ; oboInOwl:hasExactSynonym "M-phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000279" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "M phase" ; rdfs:subClassOf obo:GO_0022403 . obo:GO_0000280 obo:IAO_0000115 "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "karyokinesis" ; oboInOwl:id "GO:0000280" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "nuclear division" ; rdfs:subClassOf obo:GO_0048285 . obo:GO_0000281 obo:IAO_0000115 "A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells." ; oboInOwl:hasExactSynonym "cytokinesis after mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000281" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "mitotic cytokinesis" ; rdfs:subClassOf obo:GO_0061640, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061640 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0000302 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals." ; oboInOwl:hasExactSynonym "response to AOS", "response to ROI", "response to ROS", "response to active oxygen species", "response to reactive oxidative species", "response to reactive oxygen intermediate" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000302" ; a owl:Class ; rdfs:label "response to reactive oxygen species" ; rdfs:subClassOf obo:GO_0006979, obo:GO_1901700 . obo:GO_0000323 obo:IAO_0000115 "A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0000323" ; a owl:Class ; rdfs:label "lytic vacuole" ; rdfs:subClassOf obo:GO_0005773 . obo:GO_0000374 obo:IAO_0000115 "The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mRNA splicing" ; oboInOwl:id "GO:0000374" ; a owl:Class ; rdfs:comment "Note that Group III introns are known to be found in mRNA of plastids of euglenoid protists." ; rdfs:label "Group III intron splicing" ; rdfs:subClassOf obo:GO_0000377 . obo:GO_0000375 obo:IAO_0000115 "Splicing of RNA via a series of two transesterification reactions." ; oboInOwl:hasAlternativeId "GO:0000385", "GO:0031202" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "RNA splicing factor activity, transesterification mechanism", "pre-mRNA splicing factor activity", "spliceosomal catalysis" ; oboInOwl:id "GO:0000375" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that nuclear mRNA, Group I, Group II, and Group III introns are all spliced by a series of two transesterification reactions that occur within the RNA itself, or between two RNAs in trans splicing. Some of these require one or more proteins to stabilize the catalytic conformation, while others are autocatalytic. Note that tRNA introns are spliced by a different catalytic mechanism." ; rdfs:label "RNA splicing, via transesterification reactions" ; rdfs:subClassOf obo:GO_0008380 . obo:GO_0000377 obo:IAO_0000115 "Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lariat RNA biosynthesis", "lariat RNA formation" ; oboInOwl:id "GO:0000377" ; a owl:Class ; rdfs:label "RNA splicing, via transesterification reactions with bulged adenosine as nucleophile" ; rdfs:subClassOf obo:GO_0000375 . obo:GO_0000398 obo:IAO_0000115 "The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced." ; oboInOwl:hasAlternativeId "GO:0006374", "GO:0006375" ; oboInOwl:hasBroadSynonym "mRNA splicing", "pre-mRNA splicing" ; oboInOwl:hasExactSynonym "nuclear mRNA splicing, via spliceosome" ; oboInOwl:hasNarrowSynonym "nuclear mRNA splicing via U12-type spliceosome", "nuclear mRNA splicing via U2-type spliceosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "splicing AT-AC intron", "splicing GT-AG intron" ; oboInOwl:id "GO:0000398" ; a owl:Class ; rdfs:comment "Note that although the many U12-type introns have the sequence AT-AC at the intron termini, some introns with these terminal sequences are spliced by the U2-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron. Note that although the majority of U2-type introns have the sequence GU-AG at the intron termini, some introns with these terminal sequences are spliced by the U12-type spliceosome. The distinguishing characteristics are sequences near the 5' splice site and the branch point sequences of the intron." ; rdfs:label "mRNA splicing, via spliceosome" ; rdfs:subClassOf obo:GO_0000377, obo:GO_0006397 . obo:GO_0000422 obo:IAO_0000115 "The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25541"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "mitochondrion degradation", "mitochondrion disassembly" ; oboInOwl:hasNarrowSynonym "mitophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000422" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "autophagy of mitochondrion" ; rdfs:subClassOf obo:GO_0006914, obo:GO_0007005, obo:GO_1903008 . obo:GO_0000423 obo:IAO_0000115 "The selective autophagy process in which a mitochondrion is degraded by macroautophagy." ; oboInOwl:hasDbXref "Wikipedia:Mitophagy" ; oboInOwl:hasExactSynonym "macromitophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000423" ; a owl:Class ; rdfs:comment "Note that this terms refers to the macroautophagy process and is named by common usage. Be aware that there are a separate micromitophagy and mitophagy by induced vacuole formation processes." ; rdfs:label "mitophagy" ; rdfs:subClassOf obo:GO_0000422, obo:GO_0016236 . obo:GO_0000723 obo:IAO_0000115 "Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of telomere length" ; oboInOwl:id "GO:0000723" ; a owl:Class ; rdfs:label "telomere maintenance" ; rdfs:subClassOf obo:GO_0006259, obo:GO_0032200 . obo:GO_0000768 obo:IAO_0000115 "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ; oboInOwl:hasBroadSynonym "cell fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000768" ; a owl:Class ; rdfs:label "syncytium formation by plasma membrane fusion" ; rdfs:subClassOf obo:GO_0006949, obo:GO_0140253 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006949 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0045026 ] ) ] . obo:GO_0000781 obo:IAO_0000115 "The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres)." ; oboInOwl:hasAlternativeId "GO:0000784" ; oboInOwl:hasDbXref "SO:0000624" ; oboInOwl:hasNarrowSynonym "nuclear chromosome, telomere", "nuclear chromosome, telomeric region" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "telomere" ; oboInOwl:id "GO:0000781" ; a owl:Class ; rdfs:comment "Note that this term can be used in place of the obsolete cellular component term 'telomere ; GO:0005696'. Use with caution because this term refers to a specific region of the chromosome and not a protein complex." ; rdfs:label "chromosome, telomeric region" ; rdfs:subClassOf obo:GO_0098687 . obo:GO_0000793 obo:IAO_0000115 "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cytoplasmic mitotic chromosome", "metaphase chromosome", "mitotic chromosome" ; oboInOwl:id "GO:0000793" ; a owl:Class ; rdfs:comment "Note that this term can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes an 'open mitosis' in which the nuclear envelope breaks down during mitosis." ; rdfs:label "condensed chromosome" ; rdfs:subClassOf obo:GO_0005694 . obo:GO_0000794 obo:IAO_0000115 "A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "meiotic chromosome", "nuclear mitotic chromosome" ; oboInOwl:id "GO:0000794" ; a owl:Class ; rdfs:comment "Note that this term and its children can be used to annotate gene products that localize to a mitotic chromosome in an organism that undergoes a 'closed mitosis' in which the nuclear envelope does not break down during mitosis and for gene products that localize to a meiotic chromosome." ; rdfs:label "condensed nuclear chromosome" ; rdfs:subClassOf obo:GO_0000228, obo:GO_0000793 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000793 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0000819 obo:IAO_0000115 "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000819" ; a owl:Class ; rdfs:label "sister chromatid segregation" ; rdfs:subClassOf obo:GO_0051276, obo:GO_0098813 . obo:GO_0000902 obo:IAO_0000115 "The developmental process in which the size or shape of a cell is generated and organized." ; oboInOwl:hasAlternativeId "GO:0007148", "GO:0045790", "GO:0045791" ; oboInOwl:hasExactSynonym "cellular morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000902" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_yeast ; a owl:Class ; rdfs:label "cell morphogenesis" ; rdfs:subClassOf obo:GO_0009653 . obo:GO_0000910 obo:IAO_0000115 "The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells." ; oboInOwl:hasAlternativeId "GO:0007104", "GO:0016288", "GO:0033205" ; oboInOwl:hasDbXref "Wikipedia:Cytokinesis" ; oboInOwl:hasExactSynonym "cell cycle cytokinesis", "cytokinesis involved in cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000910" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_candida, go:goslim_generic, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. When annotating eukaryotic species, mitotic or meiotic cytokinesis should always be specified for manual annotation and for prokaryotic species use 'FtsZ-dependent cytokinesis ; GO:0043093' or Cdv-dependent cytokinesis ; GO:0061639. Also, note that cytokinesis does not necessarily result in physical separation and detachment of the two daughter cells from each other." ; rdfs:label "cytokinesis" ; rdfs:subClassOf obo:GO_0022402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051301 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0090148 ] . obo:GO_0000932 obo:IAO_0000115 "A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing." ; oboInOwl:hasDbXref "Wikipedia:P_body" ; oboInOwl:hasExactSynonym "P body", "cytoplasmic mRNA processing body" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cytoplasmic foci" ; oboInOwl:id "GO:0000932" ; a owl:Class ; rdfs:label "P-body" ; rdfs:subClassOf obo:GO_0036464 . obo:GO_0000956 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells." ; oboInOwl:hasExactSynonym "nuclear mRNA breakdown", "nuclear mRNA catabolism", "nuclear mRNA degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000956" ; a owl:Class ; rdfs:label "nuclear-transcribed mRNA catabolic process" ; rdfs:subClassOf obo:GO_0006402 . obo:GO_0000957 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000957" ; a owl:Class ; rdfs:label "mitochondrial RNA catabolic process" ; rdfs:subClassOf obo:GO_0000959, obo:GO_0006401 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006401 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0000958 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000958" ; a owl:Class ; rdfs:label "mitochondrial mRNA catabolic process" ; rdfs:subClassOf obo:GO_0000957, obo:GO_0006402 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006402 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0000959 obo:IAO_0000115 "The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000959" ; a owl:Class ; rdfs:label "mitochondrial RNA metabolic process" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0016070, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016070 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0000960 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000960" ; a owl:Class ; rdfs:label "regulation of mitochondrial RNA catabolic process" ; rdfs:subClassOf obo:GO_0031329, obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000957 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000957 ] ) ] . obo:GO_0000961 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000961" ; a owl:Class ; rdfs:label "negative regulation of mitochondrial RNA catabolic process" ; rdfs:subClassOf obo:GO_0000960, obo:GO_1902369, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000957 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000957 ] ) ] . obo:GO_0000962 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000962" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial RNA catabolic process" ; rdfs:subClassOf obo:GO_0000960, obo:GO_0031331, obo:GO_0051254, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000957 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000957 ] ) ] . obo:GO_0000963 obo:IAO_0000115 "The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0000963" ; a owl:Class ; rdfs:label "mitochondrial RNA processing" ; rdfs:subClassOf obo:GO_0000959, obo:GO_0006396, obo:GO_0140053 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006396 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0001101 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form." ; oboInOwl:hasBroadSynonym "response to acid" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to acid anion", "response to oxoanion" ; oboInOwl:id "GO:0001101" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead." ; rdfs:label "response to acid chemical" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0001556 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization." ; oboInOwl:hasDbXref "Wikipedia:Oocyte_maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001556" ; a owl:Class ; rdfs:label "oocyte maturation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0048469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048599 ] . obo:GO_0001558 obo:IAO_0000115 "Any process that modulates the frequency, rate, extent or direction of cell growth." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001558" ; a owl:Class ; rdfs:label "regulation of cell growth" ; rdfs:subClassOf obo:GO_0040008, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016049 ] ) ] . obo:GO_0001666 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level." ; oboInOwl:hasExactSynonym "response to hypoxic stress", "response to lowered oxygen tension" ; oboInOwl:hasNarrowSynonym "response to intermittent hypoxia", "response to sustained hypoxia" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001666" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%." ; rdfs:label "response to hypoxia" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0036293 . obo:GO_0001667 obo:IAO_0000115 "Cell migration that is accomplished by extension and retraction of a pseudopodium." ; oboInOwl:hasExactSynonym "ameboid cell migration", "amoeboid cell migration", "amoeboidal cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001667" ; a owl:Class ; rdfs:comment "Note that this term refers to a mode of migration rather than to any particular cell type." ; rdfs:label "ameboidal-type cell migration" ; rdfs:subClassOf obo:GO_0016477 . obo:GO_0001704 obo:IAO_0000115 "The formation of the ectoderm, mesoderm and endoderm during gastrulation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001704" ; a owl:Class ; rdfs:label "formation of primary germ layer" ; rdfs:subClassOf obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007369 ] . obo:GO_0001705 obo:IAO_0000115 "The formation of ectoderm during gastrulation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001705" ; a owl:Class ; rdfs:label "ectoderm formation" ; rdfs:subClassOf obo:GO_0001704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007398 ] . obo:GO_0001706 obo:IAO_0000115 "The formation of the endoderm during gastrulation." ; oboInOwl:hasNarrowSynonym "endoblast formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001706" ; a owl:Class ; rdfs:label "endoderm formation" ; rdfs:subClassOf obo:GO_0001704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007492 ] . obo:GO_0001707 obo:IAO_0000115 "The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001707" ; a owl:Class ; rdfs:label "mesoderm formation" ; rdfs:subClassOf obo:GO_0001704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048332 ] . obo:GO_0001708 obo:IAO_0000115 "The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001708" ; a owl:Class ; rdfs:label "cell fate specification" ; rdfs:subClassOf obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045165 ] . obo:GO_0001764 obo:IAO_0000115 "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature." ; oboInOwl:hasDbXref "Wikipedia:Neural_development#Neuron_migration", "Wikipedia:Neuron_migration" ; oboInOwl:hasExactSynonym "neuron chemotaxis", "neuronal migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neuron guidance" ; oboInOwl:id "GO:0001764" ; a owl:Class ; rdfs:label "neuron migration" ; rdfs:subClassOf obo:GO_0016477, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048699 ] . obo:GO_0001932 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein." ; oboInOwl:hasExactSynonym "regulation of protein amino acid phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001932" ; a owl:Class ; rdfs:label "regulation of protein phosphorylation" ; rdfs:subClassOf obo:GO_0031399, obo:GO_0042325, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006468 ] ) ] . obo:GO_0001933 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein." ; oboInOwl:hasExactSynonym "down regulation of protein amino acid phosphorylation", "down-regulation of protein amino acid phosphorylation", "downregulation of protein amino acid phosphorylation", "negative regulation of protein amino acid phosphorylation" ; oboInOwl:hasNarrowSynonym "inhibition of protein amino acid phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001933" ; a owl:Class ; rdfs:label "negative regulation of protein phosphorylation" ; rdfs:subClassOf obo:GO_0001932, obo:GO_0031400, obo:GO_0042326, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006468 ] ) ] . obo:GO_0001934 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein." ; oboInOwl:hasExactSynonym "positive regulation of protein amino acid phosphorylation", "up regulation of protein amino acid phosphorylation", "up-regulation of protein amino acid phosphorylation", "upregulation of protein amino acid phosphorylation" ; oboInOwl:hasNarrowSynonym "activation of protein amino acid phosphorylation", "stimulation of protein amino acid phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001934" ; a owl:Class ; rdfs:label "positive regulation of protein phosphorylation" ; rdfs:subClassOf obo:GO_0001932, obo:GO_0031401, obo:GO_0042327, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006468 ] ) ] . obo:GO_0001939 obo:IAO_0000115 "The pronucleus originating from the ovum that is being fertilized." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0001939" ; a owl:Class ; rdfs:label "female pronucleus" ; rdfs:subClassOf obo:GO_0045120 . obo:GO_0001940 obo:IAO_0000115 "The pronucleus originating from the spermatozoa that was involved in fertilization." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0001940" ; a owl:Class ; rdfs:label "male pronucleus" ; rdfs:subClassOf obo:GO_0045120 . obo:GO_0001956 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter." ; oboInOwl:hasExactSynonym "up regulation of neurotransmitter secretion", "up-regulation of neurotransmitter secretion", "upregulation of neurotransmitter secretion" ; oboInOwl:hasNarrowSynonym "activation of neurotransmitter secretion", "stimulation of neurotransmitter secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001956" ; a owl:Class ; rdfs:label "positive regulation of neurotransmitter secretion" ; rdfs:subClassOf obo:GO_0046928, obo:GO_0050806, obo:GO_0051590, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007269 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007269 ] ) ] . obo:GO_0001966 obo:IAO_0000115 "The directed movement of an animal in response to touch." ; oboInOwl:hasBroadSynonym "taxis in response to mechanical stimulus" ; oboInOwl:hasExactSynonym "stereotaxis", "taxis in response to touch stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0001966" ; a owl:Class ; rdfs:label "thigmotaxis" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0002064 obo:IAO_0000115 "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002064" ; a owl:Class ; rdfs:label "epithelial cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030855 ] . obo:GO_0002119 obo:IAO_0000115 "The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002119" ; a owl:Class ; rdfs:label "nematode larval development" ; rdfs:subClassOf obo:GO_0002164 . obo:GO_0002164 obo:IAO_0000115 "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002164" ; a owl:Class ; rdfs:label "larval development" ; rdfs:subClassOf obo:GO_0007275, obo:GO_0009791 . obo:GO_0002376 obo:IAO_0000115 "Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats." ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasDbXref "Wikipedia:Immune_system" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002376" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pir ; a owl:Class ; rdfs:comment "Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501)." ; rdfs:label "immune system process" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0002520 obo:IAO_0000115 "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002520" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "immune system development" ; rdfs:subClassOf obo:GO_0002376, obo:GO_0048731 . obo:GO_0002682 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of an immune system process." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002682" ; a owl:Class ; rdfs:label "regulation of immune system process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002376 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002376 ] ) ] . obo:GO_0002683 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process." ; oboInOwl:hasExactSynonym "down regulation of immune system process", "down-regulation of immune system process", "downregulation of immune system process" ; oboInOwl:hasNarrowSynonym "inhibition of immune system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002683" ; a owl:Class ; rdfs:label "negative regulation of immune system process" ; rdfs:subClassOf obo:GO_0002682, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002376 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002376 ] ) ] . obo:GO_0002684 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of an immune system process." ; oboInOwl:hasExactSynonym "up regulation of immune system process", "up-regulation of immune system process", "upregulation of immune system process" ; oboInOwl:hasNarrowSynonym "activation of immune system process", "stimulation of immune system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002684" ; a owl:Class ; rdfs:label "positive regulation of immune system process" ; rdfs:subClassOf obo:GO_0002682, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002376 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002376 ] ) ] . obo:GO_0002831 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002831" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "regulation of response to biotic stimulus" ; rdfs:subClassOf obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009607 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009607 ] ) ] . obo:GO_0002832 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to biotic stimulus", "down-regulation of response to biotic stimulus", "downregulation of response to biotic stimulus" ; oboInOwl:hasNarrowSynonym "inhibition of response to biotic stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002832" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "negative regulation of response to biotic stimulus" ; rdfs:subClassOf obo:GO_0002831, obo:GO_0048585, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009607 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009607 ] ) ] . obo:GO_0002833 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to biotic stimulus", "up-regulation of response to biotic stimulus", "upregulation of response to biotic stimulus" ; oboInOwl:hasNarrowSynonym "activation of response to biotic stimulus", "stimulation of response to biotic stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0002833" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "positive regulation of response to biotic stimulus" ; rdfs:subClassOf obo:GO_0002831, obo:GO_0048584, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009607 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009607 ] ) ] . obo:GO_0003006 obo:IAO_0000115 "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring." ; oboInOwl:hasNarrowSynonym "puberty" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "reproductive developmental process" ; oboInOwl:id "GO:0003006" ; a owl:Class ; rdfs:label "developmental process involved in reproduction" ; rdfs:subClassOf obo:GO_0022414, obo:GO_0032502 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000003 ] ) ] . obo:GO_0003008 obo:IAO_0000115 "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective." ; oboInOwl:hasExactSynonym "organ system process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003008" ; a owl:Class ; rdfs:label "system process" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0003012 obo:IAO_0000115 "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "muscle physiological process" ; oboInOwl:id "GO:0003012" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic ; a owl:Class ; rdfs:label "muscle system process" ; rdfs:subClassOf obo:GO_0003008 . obo:GO_0003365 obo:IAO_0000115 "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-08T04:50:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003365" ; a owl:Class ; rdfs:label "establishment of cell polarity involved in ameboidal cell migration" ; rdfs:subClassOf obo:GO_0030010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001667 ] ) ] . obo:GO_0003379 obo:IAO_0000115 "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-12-09T06:54:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0003379" ; a owl:Class ; rdfs:label "establishment of cell polarity involved in gastrulation cell migration" ; rdfs:subClassOf obo:GO_0003365, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042074 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042074 ] ) ] . obo:GO_0003674 obo:IAO_0000115 "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs." ; oboInOwl:hasAlternativeId "GO:0005554" ; oboInOwl:hasExactSynonym "molecular function" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0003674" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that, in addition to forming the root of the molecular function ontology, this term is recommended for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex.", "Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex." ; rdfs:label "molecular_function" . obo:GO_0003824 obo:IAO_0000115 "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic." ; oboInOwl:hasDbXref "Wikipedia:Enzyme" ; oboInOwl:hasExactSynonym "enzyme activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0003824" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "catalytic activity" ; rdfs:subClassOf obo:GO_0003674 . obo:GO_0003990 obo:IAO_0000115 "Catalysis of the reaction: acetylcholine + H2O = choline + acetate." ; oboInOwl:hasDbXref "EC:3.1.1.7", "MetaCyc:ACETYLCHOLINESTERASE-RXN", "RHEA:17561", "Reactome:R-HSA-372519" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "AcCholE", "acetyl.beta-methylcholinesterase activity", "acetylcholine acetylhydrolase activity", "acetylcholine hydrolase activity", "acetylthiocholinesterase activity", "choline esterase I activity", "true cholinesterase activity" ; oboInOwl:id "GO:0003990" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "acetylcholinesterase activity" ; rdfs:subClassOf obo:GO_0004104 . obo:GO_0004104 obo:IAO_0000115 "Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion." ; oboInOwl:hasDbXref "EC:3.1.1.8", "MetaCyc:CHOLINESTERASE-RXN", "RHEA:21964" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "BtChoEase activity", "acylcholine acylhydrolase activity", "anticholineesterase activity", "benzoylcholinesterase activity", "butyrylcholine esterase activity", "butyrylcholinesterase activity", "choline esterase II (unspecific) activity", "choline esterase activity", "non-specific cholinesterase activity", "propionylcholinesterase activity", "pseudocholinesterase activity" ; oboInOwl:id "GO:0004104" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "cholinesterase activity" ; rdfs:subClassOf obo:GO_0052689 . obo:GO_0005102 obo:IAO_0000115 "Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function." ; oboInOwl:hasBroadSynonym "receptor binding" ; oboInOwl:hasDbXref "Wikipedia:Ligand_(biochemistry)" ; oboInOwl:hasNarrowSynonym "receptor ligand" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "receptor-associated protein activity" ; oboInOwl:id "GO:0005102" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_plant ; a owl:Class ; rdfs:comment "Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'." ; rdfs:label "signaling receptor binding" ; rdfs:subClassOf obo:GO_0005515 . obo:GO_0005488 obo:IAO_0000115 "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule." ; oboInOwl:hasDbXref "Wikipedia:Binding_(molecular)" ; oboInOwl:hasNarrowSynonym "ligand" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005488" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children." ; rdfs:label "binding" ; rdfs:subClassOf obo:GO_0003674 . obo:GO_0005515 obo:IAO_0000115 "Binding to a protein." ; oboInOwl:hasAlternativeId "GO:0001948", "GO:0045308" ; oboInOwl:hasExactSynonym "protein amino acid binding" ; oboInOwl:hasNarrowSynonym "glycoprotein binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0005515" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "protein binding" ; rdfs:subClassOf obo:GO_0005488 . obo:GO_0005575 obo:IAO_0000115 "A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17729"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0008372" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1337158144" ; oboInOwl:hasExactSynonym "cell or subcellular entity", "cellular component" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "subcellular entity" ; oboInOwl:id "GO:0005575" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ; rdfs:label "cellular_component" . obo:GO_0005604 obo:IAO_0000115 "A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers." ; oboInOwl:hasAlternativeId "GO:0005605", "GO:0008003" ; oboInOwl:hasDbXref "Wikipedia:Basement_membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "basal lamina", "basement lamina", "lamina densa" ; oboInOwl:id "GO:0005604" ; a owl:Class ; rdfs:comment "Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer." ; rdfs:label "basement membrane" ; rdfs:subClassOf obo:GO_0062023 . obo:GO_0005622 obo:IAO_0000115 "A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17776"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Intracellular" ; oboInOwl:hasExactSynonym "internal to cell", "intracellular", "protoplasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "nucleocytoplasm", "protoplast" ; oboInOwl:id "GO:0005622" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_chembl, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:label "intracellular anatomical structure" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0005623 obo:IAO_0000115 "OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19036"^^xsd:anyURI ; obo:IAO_0000589 "cell and encapsulating structures" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1813327414", "Wikipedia:Cell_(biology)" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005623" ; a owl:Class ; rdfs:comment "This term was obsoleted because it was redundant with the root class of the cell ontology, CL:0000000." ; rdfs:label "obsolete cell" ; owl:deprecated true . obo:GO_0005634 obo:IAO_0000115 "A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1702920020", "Wikipedia:Cell_nucleus" ; oboInOwl:hasExactSynonym "cell nucleus" ; oboInOwl:hasNarrowSynonym "horsetail nucleus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005634" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "nucleus" ; rdfs:subClassOf obo:GO_0043231 . obo:GO_0005635 obo:IAO_0000115 "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space)." ; oboInOwl:hasAlternativeId "GO:0005636" ; oboInOwl:hasDbXref "Wikipedia:Nuclear_envelope" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005635" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic, go:goslim_plant ; a owl:Class ; rdfs:label "nuclear envelope" ; rdfs:subClassOf obo:GO_0031967, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0005643 obo:IAO_0000115 "A protein complex providing a discrete opening in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined." ; oboInOwl:hasAlternativeId "GO:0005644" ; oboInOwl:hasDbXref "NIF_Subcellular:sao220861693", "Wikipedia:Nuclear_pore" ; oboInOwl:hasExactSynonym "NPC", "nuclear pore complex", "nucleopore" ; oboInOwl:hasNarrowSynonym "nuclear pore membrane protein" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005643" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "nuclear pore" ; rdfs:subClassOf obo:GO_0140513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005635 ] . obo:GO_0005694 obo:IAO_0000115 "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information." ; oboInOwl:hasDbXref "Wikipedia:Chromosome" ; oboInOwl:hasNarrowSynonym "interphase chromosome", "prophase chromosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "chromatid" ; oboInOwl:id "GO:0005694" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore." ; rdfs:label "chromosome" ; rdfs:subClassOf obo:GO_0043232 . obo:GO_0005712 obo:IAO_0000115 "A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over." ; oboInOwl:hasDbXref "Wikipedia:Chiasma_(genetics)" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005712" ; a owl:Class ; rdfs:label "chiasma" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000794 ] . obo:GO_0005730 obo:IAO_0000115 "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1820400233", "Wikipedia:Nucleolus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005730" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "nucleolus" ; rdfs:subClassOf obo:GO_0043232, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031981 ] . obo:GO_0005737 obo:IAO_0000115 "The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23023"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Cytoplasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005737" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "cytoplasm" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] . obo:GO_0005739 obo:IAO_0000115 "A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1860313010", "Wikipedia:Mitochondrion" ; oboInOwl:hasExactSynonym "mitochondria" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005739" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Some anaerobic or microaerophilic organisms (e.g. Entamoeba histolytica, Giardia intestinalis and several Microsporidia species) do not have mitochondria, and contain mitochondrion-related organelles (MROs) instead, called mitosomes or hydrogenosomes, very likely derived from mitochondria. To annotate gene products located in these mitochondrial relics in species such as Entamoeba histolytica, Giardia intestinalis or others, please use GO:0032047 'mitosome' or GO:0042566 'hydrogenosome'. (See PMID:24316280 for a list of species currently known to contain mitochondrion-related organelles.)" ; rdfs:label "mitochondrion" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0005740 obo:IAO_0000115 "The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005740" ; oboInOwl:inSubset go:goslim_candida, go:goslim_yeast ; a owl:Class ; rdfs:label "mitochondrial envelope" ; rdfs:subClassOf obo:GO_0031967, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] . obo:GO_0005759 obo:IAO_0000115 "The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation." ; oboInOwl:hasAlternativeId "GO:0031980" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1804523077", "Wikipedia:Mitochondrial_matrix" ; oboInOwl:hasExactSynonym "mitochondrial lumen" ; oboInOwl:hasNarrowSynonym "mitochondrial stroma" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005759" ; a owl:Class ; rdfs:label "mitochondrial matrix" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] . obo:GO_0005764 obo:IAO_0000115 "A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "NIF_Subcellular:sao585356902", "Wikipedia:Lysosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005764" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic, go:goslim_plant ; a owl:Class ; rdfs:label "lysosome" ; rdfs:subClassOf obo:GO_0000323 . obo:GO_0005768 obo:IAO_0000115 "A vacuole to which materials ingested by endocytosis are delivered." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1720343330", "Wikipedia:Endosome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005768" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "endosome" ; rdfs:subClassOf obo:GO_0031410, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0005769 obo:IAO_0000115 "A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways." ; oboInOwl:hasDbXref "NIF_Subcellular:nlx_subcell_20090701" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005769" ; a owl:Class ; rdfs:label "early endosome" ; rdfs:subClassOf obo:GO_0005768 . obo:GO_0005770 obo:IAO_0000115 "A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center." ; oboInOwl:hasBroadSynonym "PVC" ; oboInOwl:hasDbXref "NIF_Subcellular:nlx_subcell_20090702" ; oboInOwl:hasExactSynonym "prevacuolar compartment" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005770" ; a owl:Class ; rdfs:label "late endosome" ; rdfs:subClassOf obo:GO_0005768 . obo:GO_0005773 obo:IAO_0000115 "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol." ; oboInOwl:hasDbXref "Wikipedia:Vacuole" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "vacuolar carboxypeptidase Y" ; oboInOwl:id "GO:0005773" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "vacuole" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0005775 obo:IAO_0000115 "The volume enclosed within the vacuolar membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005775" ; a owl:Class ; rdfs:label "vacuolar lumen" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031974 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0005777 obo:IAO_0000115 "A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism." ; oboInOwl:hasAlternativeId "GO:0019818" ; oboInOwl:hasBroadSynonym "peroxisome vesicle" ; oboInOwl:hasDbXref "NIF_Subcellular:sao499555322", "Wikipedia:Peroxisome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "peroxisomal" ; oboInOwl:id "GO:0005777" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "peroxisome" ; rdfs:subClassOf obo:GO_0042579 . obo:GO_0005783 obo:IAO_0000115 "The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1036339110", "Wikipedia:Endoplasmic_reticulum" ; oboInOwl:hasExactSynonym "ER" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005783" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "endoplasmic reticulum" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0005788 obo:IAO_0000115 "The volume enclosed by the membranes of the endoplasmic reticulum." ; oboInOwl:hasAlternativeId "GO:0016022" ; oboInOwl:hasExactSynonym "ER cisterna", "ER lumen", "cisternal lumen", "endoplasmic reticulum cisterna" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005788" ; a owl:Class ; rdfs:label "endoplasmic reticulum lumen" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005783 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031974 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005783 ] ) ] . obo:GO_0005794 obo:IAO_0000115 "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways." ; oboInOwl:hasBroadSynonym "Golgi" ; oboInOwl:hasDbXref "NIF_Subcellular:sao451912436", "Wikipedia:Golgi_apparatus" ; oboInOwl:hasExactSynonym "Golgi complex" ; oboInOwl:hasNarrowSynonym "Golgi ribbon" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005794" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon." ; rdfs:label "Golgi apparatus" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0005818 obo:IAO_0000115 "An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005818" ; a owl:Class ; rdfs:label "aster" ; rdfs:subClassOf obo:GO_0043232, obo:GO_0099080, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005819 ] . obo:GO_0005819 obo:IAO_0000115 "The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart." ; oboInOwl:hasDbXref "Wikipedia:Spindle_apparatus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005819" ; a owl:Class ; rdfs:label "spindle" ; rdfs:subClassOf obo:GO_0043232, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015630 ] . obo:GO_0005829 obo:IAO_0000115 "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes." ; oboInOwl:hasDbXref "NIF_Subcellular:sao101633890", "Wikipedia:Cytosol" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005829" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_plant ; a owl:Class ; rdfs:label "cytosol" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0005856 obo:IAO_0000115 "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." ; oboInOwl:hasDbXref "Wikipedia:Cytoskeleton" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005856" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "cytoskeleton" ; rdfs:subClassOf obo:GO_0043232 . obo:GO_0005859 obo:IAO_0000115 "A filament of myosin found in a muscle cell of any type." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005859" ; a owl:Class ; rdfs:label "muscle myosin complex" ; rdfs:subClassOf obo:GO_0016460, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043292 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016460 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043292 ] ) ] . obo:GO_0005863 obo:IAO_0000115 "Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005863" ; a owl:Class ; rdfs:label "striated muscle myosin thick filament" ; rdfs:subClassOf obo:GO_0032982, obo:GO_0036379, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030017 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005859 ] . obo:GO_0005874 obo:IAO_0000115 "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1846835077", "Wikipedia:Microtubule" ; oboInOwl:hasExactSynonym "microtubuli", "microtubulus" ; oboInOwl:hasNarrowSynonym "neurotubule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005874" ; oboInOwl:inSubset go:goslim_metagenomics ; a owl:Class ; rdfs:label "microtubule" ; rdfs:subClassOf obo:GO_0099513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015630 ] . obo:GO_0005876 obo:IAO_0000115 "Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005876" ; a owl:Class ; rdfs:label "spindle microtubule" ; rdfs:subClassOf obo:GO_0005874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005819 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005874 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005819 ] ) ] . obo:GO_0005879 obo:IAO_0000115 "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005879" ; a owl:Class ; rdfs:label "axonemal microtubule" ; rdfs:subClassOf obo:GO_0005881, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005930 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005874 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005930 ] ) ] . obo:GO_0005880 obo:IAO_0000115 "Any microtubule in the nucleus of a cell." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005880" ; a owl:Class ; rdfs:label "nuclear microtubule" ; rdfs:subClassOf obo:GO_0005874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005874 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0005881 obo:IAO_0000115 "Any microtubule in the cytoplasm of a cell." ; oboInOwl:hasNarrowSynonym "non-spindle-associated astral microtubule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005881" ; a owl:Class ; rdfs:label "cytoplasmic microtubule" ; rdfs:subClassOf obo:GO_0005874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005874 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0005884 obo:IAO_0000115 "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane." ; oboInOwl:hasDbXref "FMA:63850", "NIF_Subcellular:sao1588493326", "Wikipedia:Actin" ; oboInOwl:hasExactSynonym "microfilament" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005884" ; a owl:Class ; rdfs:label "actin filament" ; rdfs:subClassOf obo:GO_0099513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015629 ] . obo:GO_0005886 obo:IAO_0000115 "The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins." ; oboInOwl:hasAlternativeId "GO:0005887", "GO:0005904" ; oboInOwl:hasBroadSynonym "juxtamembrane" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1663586795", "Wikipedia:Cell_membrane" ; oboInOwl:hasExactSynonym "cell membrane", "cellular membrane", "cytoplasmic membrane", "plasmalemma" ; oboInOwl:hasNarrowSynonym "bacterial inner membrane", "inner endospore membrane", "integral component of plasma membrane", "integral to plasma membrane", "plasma membrane lipid bilayer" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005886" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "plasma membrane" ; rdfs:subClassOf obo:GO_0016020, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071944 ] . obo:GO_0005911 obo:IAO_0000115 "A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22122"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "cell-cell contact region", "cell-cell contact zone" ; oboInOwl:hasDbXref "NIF_Subcellular:sao1922892319" ; oboInOwl:hasExactSynonym "intercellular junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005911" ; a owl:Class ; rdfs:label "cell-cell junction" ; rdfs:subClassOf obo:GO_0070161 . obo:GO_0005912 obo:IAO_0000115 "A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules." ; oboInOwl:hasAlternativeId "GO:0005913" ; oboInOwl:hasDbXref "Wikipedia:Adherens_junction" ; oboInOwl:hasExactSynonym "cell-cell adherens junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005912" ; a owl:Class ; rdfs:label "adherens junction" ; rdfs:subClassOf obo:GO_0005911 . obo:GO_0005923 obo:IAO_0000115 "An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1939999134", "Wikipedia:Tight_junction" ; oboInOwl:hasExactSynonym "zonula occludens" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005923" ; a owl:Class ; rdfs:label "bicellular tight junction" ; rdfs:subClassOf obo:GO_0070160, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043296 ] . obo:GO_0005929 obo:IAO_0000115 "A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body." ; obo:RO_0002161 obo:NCBITaxon_3176, obo:NCBITaxon_3312, obo:NCBITaxon_3378, obo:NCBITaxon_3398, obo:NCBITaxon_4890, obo:NCBITaxon_5782 ; oboInOwl:hasAlternativeId "GO:0072372" ; oboInOwl:hasDbXref "FMA:67181", "NIF_Subcellular:sao787716553", "Wikipedia:Cilium" ; oboInOwl:hasExactSynonym "eukaryotic flagellum", "microtubule-based flagellum" ; oboInOwl:hasNarrowSynonym "primary cilium" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "flagellum" ; oboInOwl:id "GO:0005929" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms." ; rdfs:label "cilium" ; rdfs:subClassOf obo:GO_0043227, obo:GO_0120025, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030990 ] . obo:GO_0005930 obo:IAO_0000115 "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements." ; oboInOwl:hasAlternativeId "GO:0035085", "GO:0035086" ; oboInOwl:hasDbXref "Wikipedia:Axoneme" ; oboInOwl:hasExactSynonym "ciliary axoneme", "cilium axoneme", "flagellar axoneme", "flagellum axoneme" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0005930" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane." ; rdfs:label "axoneme" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005856 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0097014 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005874 ] . obo:GO_0005938 obo:IAO_0000115 "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/26298"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Cell_cortex" ; oboInOwl:hasNarrowSynonym "ectoplasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cell periphery", "peripheral cytoplasm" ; oboInOwl:id "GO:0005938" ; oboInOwl:inSubset go:goslim_candida, go:goslim_yeast ; a owl:Class ; rdfs:label "cell cortex" ; rdfs:subClassOf obo:GO_0005737, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071944 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071944 ] ) ] . obo:GO_0006066 obo:IAO_0000115 "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom." ; oboInOwl:hasExactSynonym "alcohol metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006066" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:label "alcohol metabolic process" ; rdfs:subClassOf obo:GO_0044281, obo:GO_1901615 . obo:GO_0006139 obo:IAO_0000115 "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasAlternativeId "GO:0055134" ; oboInOwl:hasExactSynonym "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism", "nucleobase, nucleoside, nucleotide and nucleic acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nucleobase, nucleoside and nucleotide metabolic process", "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:id "GO:0006139" ; oboInOwl:inSubset go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "nucleobase-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_0034641, obo:GO_0044238, obo:GO_0046483, obo:GO_1901360 . obo:GO_0006259 obo:IAO_0000115 "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides." ; oboInOwl:hasAlternativeId "GO:0055132" ; oboInOwl:hasExactSynonym "DNA metabolism", "cellular DNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006259" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "DNA metabolic process" ; rdfs:subClassOf obo:GO_0090304 . obo:GO_0006260 obo:IAO_0000115 "The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/10596"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0055133" ; oboInOwl:hasDbXref "Wikipedia:DNA_replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006260" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:comment "DNA biosynthesis is only part of this process. See also the biological process terms 'DNA-dependent DNA replication ; GO:0006261' and 'RNA-dependent DNA replication ; GO:0006278'." ; rdfs:label "DNA replication" ; rdfs:subClassOf obo:GO_0006259, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0071897 ] . obo:GO_0006261 obo:IAO_0000115 "A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22572"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006262", "GO:0006263" ; oboInOwl:hasExactSynonym "DNA-dependent DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006261" ; a owl:Class ; rdfs:label "DNA-templated DNA replication" ; rdfs:subClassOf obo:GO_0006260 . obo:GO_0006264 obo:IAO_0000115 "The process in which new strands of DNA are synthesized in the mitochondrion." ; oboInOwl:hasExactSynonym "mtDNA replication", "replication of mitochondrial DNA" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitochondrial DNA synthesis", "mtDNA synthesis" ; oboInOwl:id "GO:0006264" ; a owl:Class ; rdfs:label "mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0006261, obo:GO_0032042 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006260 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0006270 obo:IAO_0000115 "The process in which DNA-dependent DNA replication is started; it begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, followed by DNA unwinding." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/10596"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0042024" ; oboInOwl:hasExactSynonym "DNA-dependent DNA replication initiation" ; oboInOwl:hasNarrowSynonym "DNA endoreduplication initiation", "DNA re-replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006270" ; a owl:Class ; rdfs:label "DNA replication initiation" ; rdfs:subClassOf obo:GO_0006259, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006261 ] . obo:GO_0006275 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of DNA replication." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006275" ; a owl:Class ; rdfs:label "regulation of DNA replication" ; rdfs:subClassOf obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006260 ] ) ] . obo:GO_0006279 obo:IAO_0000115 "The replication of DNA that precedes meiotic cell division." ; oboInOwl:hasAlternativeId "GO:1902968" ; oboInOwl:hasExactSynonym "DNA replication involved in S phase involved in meiotic cell cycle", "DNA replication involved in S-phase involved in meiotic cell cycle", "meiotic cell cycle DNA replication", "meiotic nuclear cell cycle DNA replication", "nuclear cell cycle DNA replication involved in meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA replication during S phase involved in meiotic cell cycle", "meiotic DNA replication", "meiotic DNA synthesis", "premeiotic DNA synthesis" ; oboInOwl:id "GO:0006279" ; a owl:Class ; rdfs:label "premeiotic DNA replication" ; rdfs:subClassOf obo:GO_0033260, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0033260 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0006310 obo:IAO_0000115 "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006310" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "DNA recombination" ; rdfs:subClassOf obo:GO_0006259 . obo:GO_0006325 obo:IAO_0000115 "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22130"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/23549"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006333", "GO:0006336", "GO:0016568", "GO:0031497", "GO:0034724" ; oboInOwl:hasBroadSynonym "chromatin maintenance" ; oboInOwl:hasExactSynonym "chromatin organisation", "establishment of chromatin architecture", "establishment or maintenance of chromatin architecture" ; oboInOwl:hasNarrowSynonym "DNA replication-independent chromatin assembly", "DNA replication-independent chromatin organization", "DNA replication-independent nucleosome organisation", "DNA replication-independent nuclesome assembly", "chromatin assembly", "transcription-coupled nucleosome assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromatin assembly or disassembly", "chromatin assembly/disassembly", "chromatin modification" ; oboInOwl:id "GO:0006325" ; oboInOwl:inSubset go:goslim_generic, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:label "chromatin organization" ; rdfs:subClassOf obo:GO_0071824 . obo:GO_0006338 obo:IAO_0000115 "A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21732"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/21748"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0043044" ; oboInOwl:hasExactSynonym "chromatin modeling", "chromatin modelling", "chromatin remodelling" ; oboInOwl:hasNarrowSynonym "ATP-dependent chromatin remodeling", "ATP-dependent chromatin remodelling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006338" ; a owl:Class ; rdfs:label "chromatin remodeling" ; rdfs:subClassOf obo:GO_0006325 . obo:GO_0006351 obo:IAO_0000115 "The synthesis of an RNA transcript from a DNA template." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14854"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/16737"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/22258"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/22555"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0001121", "GO:0006350", "GO:0061018", "GO:0061022" ; oboInOwl:hasBroadSynonym "cellular transcription", "transcription" ; oboInOwl:hasDbXref "Wikipedia:Transcription_(genetics)" ; oboInOwl:hasExactSynonym "DNA-dependent transcription", "transcription, DNA-dependent", "transcription, DNA-templated" ; oboInOwl:hasNarrowSynonym "bacterial transcription", "transcription from bacterial-type RNA polymerase promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006351" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "DNA-templated transcription" ; rdfs:subClassOf obo:GO_0032774, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010467 ] . obo:GO_0006355 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25256"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0032583", "GO:0045449", "GO:0061019" ; oboInOwl:hasBroadSynonym "transcriptional control" ; oboInOwl:hasExactSynonym "regulation of cellular transcription, DNA-dependent", "regulation of transcription, DNA-dependent", "regulation of transcription, DNA-templated" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of gene-specific transcription" ; oboInOwl:id "GO:0006355" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "regulation of DNA-templated transcription" ; rdfs:subClassOf obo:GO_0010468, obo:GO_2001141, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006351 ] ) ] . obo:GO_0006390 obo:IAO_0000115 "The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14854"^^xsd:anyURI ; oboInOwl:hasExactSynonym "transcription from mitochondrial promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006390" ; a owl:Class ; rdfs:label "mitochondrial transcription" ; rdfs:subClassOf obo:GO_0000959, obo:GO_0006351, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140053 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006351 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0006396 obo:IAO_0000115 "Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules." ; oboInOwl:hasAlternativeId "GO:0006394" ; oboInOwl:hasDbXref "Wikipedia:Post-transcriptional_modification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006396" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:label "RNA processing" ; rdfs:subClassOf obo:GO_0016070, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010467 ] . obo:GO_0006397 obo:IAO_0000115 "Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mRNA maturation" ; oboInOwl:id "GO:0006397" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_yeast ; a owl:Class ; rdfs:label "mRNA processing" ; rdfs:subClassOf obo:GO_0006396, obo:GO_0016071 . obo:GO_0006401 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; oboInOwl:hasExactSynonym "RNA breakdown", "RNA catabolism", "RNA degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006401" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "RNA catabolic process" ; rdfs:subClassOf obo:GO_0009057, obo:GO_0016070, obo:GO_0034655 . obo:GO_0006402 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." ; oboInOwl:hasExactSynonym "mRNA breakdown", "mRNA catabolism", "mRNA degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mRNA decay" ; oboInOwl:id "GO:0006402" ; a owl:Class ; rdfs:label "mRNA catabolic process" ; rdfs:subClassOf obo:GO_0006401, obo:GO_0010629, obo:GO_0016071 . obo:GO_0006403 obo:IAO_0000115 "A process in which RNA is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "RNA localisation", "establishment and maintenance of RNA localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006403" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "RNA localization" ; rdfs:subClassOf obo:GO_0033036 . obo:GO_0006405 obo:IAO_0000115 "The directed movement of RNA from the nucleus to the cytoplasm." ; oboInOwl:hasExactSynonym "RNA export from cell nucleus", "RNA export out of nucleus", "RNA transport from nucleus to cytoplasm", "RNA-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006405" ; a owl:Class ; rdfs:label "RNA export from nucleus" ; rdfs:subClassOf obo:GO_0050658, obo:GO_0051168 . obo:GO_0006406 obo:IAO_0000115 "The directed movement of mRNA from the nucleus to the cytoplasm." ; oboInOwl:hasExactSynonym "mRNA export from cell nucleus", "mRNA export out of nucleus", "mRNA transport from nucleus to cytoplasm", "mRNA-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006406" ; a owl:Class ; rdfs:label "mRNA export from nucleus" ; rdfs:subClassOf obo:GO_0006405, obo:GO_0051028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010467 ] . obo:GO_0006412 obo:IAO_0000115 "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome." ; oboInOwl:hasAlternativeId "GO:0006416", "GO:0006453", "GO:0043037" ; oboInOwl:hasDbXref "Wikipedia:Translation_(genetics)" ; oboInOwl:hasExactSynonym "protein anabolism", "protein biosynthesis", "protein biosynthetic process", "protein formation", "protein synthesis", "protein translation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006412" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:prokaryote_subset ; a owl:Class ; rdfs:label "translation" ; rdfs:subClassOf obo:GO_0009059, obo:GO_0019538, obo:GO_0043043, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010467 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0006414 ] . obo:GO_0006414 obo:IAO_0000115 "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis." ; oboInOwl:hasAlternativeId "GO:0006442", "GO:0006455" ; oboInOwl:hasBroadSynonym "protein synthesis elongation" ; oboInOwl:hasExactSynonym "translation elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006414" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "translational elongation" ; rdfs:subClassOf obo:GO_0009059, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006412 ] . obo:GO_0006417 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ; oboInOwl:hasAlternativeId "GO:0006445" ; oboInOwl:hasExactSynonym "regulation of protein anabolism", "regulation of protein biosynthesis", "regulation of protein formation", "regulation of protein synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006417" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of translation" ; rdfs:subClassOf obo:GO_0010608, obo:GO_0034248, obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0006448 obo:IAO_0000115 "Any process that modulates the frequency, rate, extent or accuracy of translational elongation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006448" ; a owl:Class ; rdfs:label "regulation of translational elongation" ; rdfs:subClassOf obo:GO_0006417, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006414 ] ) ] . obo:GO_0006468 obo:IAO_0000115 "The process of introducing a phosphate group on to a protein." ; oboInOwl:hasExactSynonym "protein amino acid phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006468" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_yeast ; a owl:Class ; rdfs:label "protein phosphorylation" ; rdfs:subClassOf obo:GO_0016310, obo:GO_0036211 . obo:GO_0006479 obo:IAO_0000115 "The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom." ; oboInOwl:hasExactSynonym "protein amino acid methylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006479" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "protein methylation" ; rdfs:subClassOf obo:GO_0008213, obo:GO_0043414 . obo:GO_0006518 obo:IAO_0000115 "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another." ; oboInOwl:hasExactSynonym "peptide metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006518" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "peptide metabolic process" ; rdfs:subClassOf obo:GO_0043603, obo:GO_1901564 . obo:GO_0006576 obo:IAO_0000115 "The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ; oboInOwl:hasExactSynonym "biogenic amine metabolism", "cellular biogenic amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006576" ; a owl:Class ; rdfs:label "biogenic amine metabolic process" ; rdfs:subClassOf obo:GO_0009308 . obo:GO_0006584 obo:IAO_0000115 "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; oboInOwl:hasExactSynonym "catecholamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006584" ; a owl:Class ; rdfs:label "catecholamine metabolic process" ; rdfs:subClassOf obo:GO_0006576, obo:GO_0009712 . obo:GO_0006611 obo:IAO_0000115 "The directed movement of a protein from the nucleus into the cytoplasm." ; oboInOwl:hasAlternativeId "GO:0097349" ; oboInOwl:hasExactSynonym "protein export from cell nucleus", "protein export out of nucleus", "protein transport from nucleus to cytoplasm", "protein-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "copper-induced protein export from nucleus" ; oboInOwl:id "GO:0006611" ; a owl:Class ; rdfs:label "protein export from nucleus" ; rdfs:subClassOf obo:GO_0006886, obo:GO_0051168 . obo:GO_0006629 obo:IAO_0000115 "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." ; oboInOwl:hasDbXref "Wikipedia:Lipid_metabolism" ; oboInOwl:hasExactSynonym "lipid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006629" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "lipid metabolic process" ; rdfs:subClassOf obo:GO_0044238, obo:GO_0071704 . obo:GO_0006725 obo:IAO_0000115 "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells." ; oboInOwl:hasExactSynonym "aromatic compound metabolism" ; oboInOwl:hasNarrowSynonym "aromatic hydrocarbon metabolic process", "aromatic hydrocarbon metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006725" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular aromatic compound metabolic process" ; rdfs:subClassOf obo:GO_0044237 . obo:GO_0006793 obo:IAO_0000115 "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4)." ; oboInOwl:hasExactSynonym "phosphorus metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006793" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "phosphorus metabolic process" ; rdfs:subClassOf obo:GO_0044237 . obo:GO_0006796 obo:IAO_0000115 "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid." ; oboInOwl:hasExactSynonym "phosphate metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "phosphate metabolic process" ; oboInOwl:id "GO:0006796" ; a owl:Class ; rdfs:label "phosphate-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006793 . obo:GO_0006807 obo:IAO_0000115 "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen." ; oboInOwl:hasExactSynonym "nitrogen compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006807" ; oboInOwl:inSubset go:goslim_metagenomics, go:goslim_pir ; a owl:Class ; rdfs:label "nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0006810 obo:IAO_0000115 "The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20292"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-12-13T16:25:32Z" ; oboInOwl:hasAlternativeId "GO:0015457", "GO:0015460", "GO:0044765" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism transport" ; oboInOwl:id "GO:0006810" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport." ; rdfs:label "transport" ; rdfs:subClassOf obo:GO_0051234 . obo:GO_0006836 obo:IAO_0000115 "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell." ; oboInOwl:hasNarrowSynonym "sodium:neurotransmitter transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006836" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "neurotransmitter transport" ; rdfs:subClassOf obo:GO_0006810 . obo:GO_0006873 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "cellular ion homeostasis" ; oboInOwl:hasExactSynonym "cellular monoatomic ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006873" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "intracellular monoatomic ion homeostasis" ; rdfs:subClassOf obo:GO_0050801, obo:GO_0055082 . obo:GO_0006885 obo:IAO_0000115 "Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell." ; oboInOwl:hasExactSynonym "hydrogen ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006885" ; a owl:Class ; rdfs:label "regulation of pH" ; rdfs:subClassOf obo:GO_0055080, obo:GO_0065007 . obo:GO_0006886 obo:IAO_0000115 "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell." ; oboInOwl:hasAlternativeId "GO:0032779" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "copper-induced intracellular protein transport" ; oboInOwl:id "GO:0006886" ; oboInOwl:inSubset go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "intracellular protein transport" ; rdfs:subClassOf obo:GO_0015031, obo:GO_0046907, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008104 ] . obo:GO_0006887 obo:IAO_0000115 "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell." ; oboInOwl:hasAlternativeId "GO:0016194", "GO:0016195" ; oboInOwl:hasDbXref "Wikipedia:Exocytosis" ; oboInOwl:hasExactSynonym "vesicle exocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nonselective vesicle exocytosis" ; oboInOwl:id "GO:0006887" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "exocytosis" ; rdfs:subClassOf obo:GO_0016192, obo:GO_0032940, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0099500 ] . obo:GO_0006897 obo:IAO_0000115 "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24907"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/25268"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0016193", "GO:0016196", "GO:0098701" ; oboInOwl:hasDbXref "Wikipedia:Endocytosis" ; oboInOwl:hasExactSynonym "endocytic import into cell", "vesicle endocytosis" ; oboInOwl:hasNarrowSynonym "plasma membrane invagination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nonselective vesicle endocytosis" ; oboInOwl:id "GO:0006897" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "endocytosis" ; rdfs:subClassOf obo:GO_0016192, obo:GO_0098657, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0006900 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0010324 ] . obo:GO_0006898 obo:IAO_0000115 "An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles." ; oboInOwl:hasDbXref "Wikipedia:Receptor-mediated_endocytosis" ; oboInOwl:hasExactSynonym "receptor mediated endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006898" ; a owl:Class ; rdfs:label "receptor-mediated endocytosis" ; rdfs:subClassOf obo:GO_0006897 . obo:GO_0006900 obo:IAO_0000115 "The evagination of a membrane, resulting in formation of a vesicle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-19T15:26:17Z" ; oboInOwl:hasAlternativeId "GO:0006902", "GO:1902591" ; oboInOwl:hasExactSynonym "membrane evagination", "vesicle biosynthesis", "vesicle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nonselective vesicle assembly", "single organism membrane budding", "single-organism membrane budding", "vesicle budding" ; oboInOwl:id "GO:0006900" ; a owl:Class ; rdfs:label "vesicle budding from membrane" ; rdfs:subClassOf obo:GO_0016050, obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016192 ] . obo:GO_0006906 obo:IAO_0000115 "Fusion of the membrane of a transport vesicle with its target membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006906" ; a owl:Class ; rdfs:label "vesicle fusion" ; rdfs:subClassOf obo:GO_0016050, obo:GO_0090174, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016192 ] . obo:GO_0006909 obo:IAO_0000115 "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24907"^^xsd:anyURI ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "Wikipedia:Phagocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006909" ; a owl:Class ; rdfs:label "phagocytosis" ; rdfs:subClassOf obo:GO_0006897 . obo:GO_0006910 obo:IAO_0000115 "The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell." ; oboInOwl:hasExactSynonym "recognition of phagocytosed substance by phagocytic cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006910" ; a owl:Class ; rdfs:comment "Note that cell surface molecules involved in the direct binding of bacteria may be also annotated to the molecular function term 'bacterial cell surface binding ; GO:0051635'. Note that cell surface molecules involved in the direct binding to opsonins such as complement components or antibodies may be also annotated to the term 'opsonin binding ; GO:0001846'." ; rdfs:label "phagocytosis, recognition" ; rdfs:subClassOf obo:GO_0008037, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006909 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0038024 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008037 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0006911 obo:IAO_0000115 "The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "phagosome biosynthesis", "phagosome formation" ; oboInOwl:id "GO:0006911" ; a owl:Class ; rdfs:label "phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0099024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099024 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0006913 obo:IAO_0000115 "The directed movement of molecules between the nucleus and the cytoplasm." ; oboInOwl:hasAlternativeId "GO:0000063" ; oboInOwl:hasNarrowSynonym "nucleocytoplasmic shuttling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006913" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pombe ; a owl:Class ; rdfs:comment "Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed." ; rdfs:label "nucleocytoplasmic transport" ; rdfs:subClassOf obo:GO_0051169 . obo:GO_0006914 obo:IAO_0000115 "The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25541#issuecomment-1740659745"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0016238" ; oboInOwl:hasDbXref "Wikipedia:Autophagy_(cellular)" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006914" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe ; a owl:Class ; rdfs:label "autophagy" ; rdfs:subClassOf obo:GO_0044248, obo:GO_0061919 . obo:GO_0006915 obo:IAO_0000115 "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died." ; obo:RO_0002161 obo:NCBITaxon_2, obo:NCBITaxon_4896 ; oboInOwl:hasAlternativeId "GO:0006917", "GO:0008632" ; oboInOwl:hasBroadSynonym "cell suicide", "cellular suicide" ; oboInOwl:hasDbXref "Wikipedia:Apoptosis" ; oboInOwl:hasExactSynonym "apoptotic cell death", "apoptotic programmed cell death", "programmed cell death by apoptosis" ; oboInOwl:hasNarrowSynonym "activation of apoptosis", "apoptosis", "apoptosis signaling", "apoptotic program", "type I programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "apoptosis activator activity", "caspase-dependent programmed cell death", "commitment to apoptosis", "induction of apoptosis", "induction of apoptosis by p53", "signaling (initiator) caspase activity" ; oboInOwl:id "GO:0006915" ; a owl:Class ; rdfs:label "apoptotic process" ; rdfs:subClassOf obo:GO_0012501 . obo:GO_0006935 obo:IAO_0000115 "The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ; oboInOwl:hasDbXref "Wikipedia:Chemotaxis" ; oboInOwl:hasExactSynonym "taxis in response to chemical stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006935" ; a owl:Class ; rdfs:label "chemotaxis" ; rdfs:subClassOf obo:GO_0042330, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042221 ] . obo:GO_0006936 obo:IAO_0000115 "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis." ; oboInOwl:hasDbXref "Wikipedia:Muscle_contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006936" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "muscle contraction" ; rdfs:subClassOf obo:GO_0003012 . obo:GO_0006937 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of muscle contraction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006937" ; a owl:Class ; rdfs:label "regulation of muscle contraction" ; rdfs:subClassOf obo:GO_0090257, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006936 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006936 ] ) ] . obo:GO_0006949 obo:IAO_0000115 "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006949" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "syncytium formation" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0048646 . obo:GO_0006950 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to abiotic stress", "response to biotic stress" ; oboInOwl:id "GO:0006950" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to stress" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0006952 obo:IAO_0000115 "Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack." ; oboInOwl:hasAlternativeId "GO:0002217", "GO:0042829" ; oboInOwl:hasExactSynonym "defence response", "physiological defense response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "antimicrobial peptide activity", "defense/immunity protein activity" ; oboInOwl:id "GO:0006952" ; a owl:Class ; rdfs:label "defense response" ; rdfs:subClassOf obo:GO_0006950 . obo:GO_0006955 obo:IAO_0000115 "Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006955" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "immune response" ; rdfs:subClassOf obo:GO_0002376, obo:GO_0050896 . obo:GO_0006970 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:hasExactSynonym "osmotic response", "osmotic stress response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006970" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "response to osmotic stress" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0009628 . obo:GO_0006974 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24775"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0034984" ; oboInOwl:hasBroadSynonym "response to DNA damage stimulus" ; oboInOwl:hasExactSynonym "cellular DNA damage response", "cellular response to DNA damage stimulus", "response to genotoxic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006974" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "DNA damage response" ; rdfs:subClassOf obo:GO_0033554 . obo:GO_0006979 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006979" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "response to oxidative stress" ; rdfs:subClassOf obo:GO_0006950 . obo:GO_0006983 obo:IAO_0000115 "The series of molecular signals initiated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB." ; oboInOwl:hasAlternativeId "GO:0006985" ; oboInOwl:hasExactSynonym "EOR", "ER-overload response", "endoplasmic reticulum overload response" ; oboInOwl:hasNarrowSynonym "EOR-mediated NF-kappaB activation", "EOR-mediated activation of NF-kappaB", "positive regulation of NF-kappaB transcription factor activity by EOR", "positive regulation of NF-kappaB transcription factor activity by ER overload response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006983" ; a owl:Class ; rdfs:label "ER overload response" ; rdfs:subClassOf obo:GO_0006984, obo:GO_0034976, obo:GO_0071216 . obo:GO_0006984 obo:IAO_0000115 "The series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation." ; oboInOwl:hasExactSynonym "ER to nucleus signaling pathway", "ER to nucleus signalling pathway", "ER-nuclear signaling pathway", "ER-nuclear signalling pathway", "endoplasmic reticulum to nucleus signaling pathway", "endoplasmic reticulum-nuclear signaling pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0006984" ; a owl:Class ; rdfs:label "ER-nucleus signaling pathway" ; rdfs:subClassOf obo:GO_0007165 . obo:GO_0006986 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heat shock protein activity" ; oboInOwl:id "GO:0006986" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to one specific response to the presence of unfolded proteins in the ER." ; rdfs:label "response to unfolded protein" ; rdfs:subClassOf obo:GO_0035966 . obo:GO_0006996 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-19T15:25:51Z" ; oboInOwl:hasAlternativeId "GO:1902589" ; oboInOwl:hasExactSynonym "organelle organisation", "single organism organelle organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "organelle organization and biogenesis", "single-organism organelle organization" ; oboInOwl:id "GO:0006996" ; oboInOwl:inSubset go:goslim_candida, go:goslim_pir ; a owl:Class ; rdfs:label "organelle organization" ; rdfs:subClassOf obo:GO_0016043 . obo:GO_0006997 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus." ; oboInOwl:hasAlternativeId "GO:0048287" ; oboInOwl:hasExactSynonym "nuclear organisation", "nuclear organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear morphology", "nuclear organization and biogenesis", "nucleus organization and biogenesis" ; oboInOwl:id "GO:0006997" ; oboInOwl:inSubset go:goslim_candida, go:goslim_drosophila, go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "nucleus organization" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0006998 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope." ; oboInOwl:hasExactSynonym "nuclear envelope organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear envelope organization and biogenesis" ; oboInOwl:id "GO:0006998" ; a owl:Class ; rdfs:label "nuclear envelope organization" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006997 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010256 ] . obo:GO_0007005 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components." ; oboInOwl:hasExactSynonym "mitochondria organization", "mitochondrion organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitochondrion organization and biogenesis" ; oboInOwl:id "GO:0007005" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:label "mitochondrion organization" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0007006 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion." ; oboInOwl:hasExactSynonym "mitochondrial membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitochondrial membrane organization and biogenesis" ; oboInOwl:id "GO:0007006" ; a owl:Class ; rdfs:label "mitochondrial membrane organization" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0007005, obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061024 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0007009 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane." ; oboInOwl:hasExactSynonym "plasma membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "plasma membrane organization and biogenesis" ; oboInOwl:id "GO:0007009" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "plasma membrane organization" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010256 ] . obo:GO_0007010 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." ; oboInOwl:hasExactSynonym "cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cytoskeletal organization and biogenesis", "cytoskeletal regulator activity", "cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0007010" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "cytoskeleton organization" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0007017 obo:IAO_0000115 "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007017" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "microtubule-based process" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0007018 obo:IAO_0000115 "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007018" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic ; a owl:Class ; rdfs:label "microtubule-based movement" ; rdfs:subClassOf obo:GO_0007017 . obo:GO_0007019 obo:IAO_0000115 "The removal of tubulin heterodimers from one or both ends of a microtubule." ; oboInOwl:hasExactSynonym "microtubule disassembly", "microtubule shortening" ; oboInOwl:hasNarrowSynonym "microtubule catastrophe", "microtubule depolymerization during nuclear congression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007019" ; a owl:Class ; rdfs:label "microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031109, obo:GO_0051261, obo:GO_0097435 . obo:GO_0007020 obo:IAO_0000115 "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation)." ; oboInOwl:hasDbXref "Wikipedia:Microtubule_nucleation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007020" ; a owl:Class ; rdfs:label "microtubule nucleation" ; rdfs:subClassOf obo:GO_0000226, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046785 ] . obo:GO_0007026 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol." ; oboInOwl:hasExactSynonym "down regulation of microtubule depolymerization", "down-regulation of microtubule depolymerization", "downregulation of microtubule depolymerization", "microtubule stabilization", "negative regulation of microtubule disassembly" ; oboInOwl:hasNarrowSynonym "inhibition of microtubule depolymerization", "microtubule rescue", "negative regulation of microtubule catastrophe" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007026" ; a owl:Class ; rdfs:label "negative regulation of microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031111, obo:GO_0031114, obo:GO_1901880, obo:GO_1902904, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007019 ] ) ] . obo:GO_0007027 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme." ; oboInOwl:hasExactSynonym "axonemal microtubule stabilization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of microtubule depolymerization in axoneme" ; oboInOwl:id "GO:0007027" ; a owl:Class ; rdfs:label "negative regulation of axonemal microtubule depolymerization" ; rdfs:subClassOf obo:GO_0007026, obo:GO_0010937, obo:GO_0031345, obo:GO_0120035, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060404 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060404 ] ) ] . obo:GO_0007028 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures." ; oboInOwl:hasExactSynonym "cytoplasm organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cytoplasm organization and biogenesis" ; oboInOwl:id "GO:0007028" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cytoplasm organization" ; rdfs:subClassOf obo:GO_0016043 . obo:GO_0007031 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." ; oboInOwl:hasExactSynonym "peroxisome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "peroxisome organization and biogenesis" ; oboInOwl:id "GO:0007031" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:label "peroxisome organization" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0007033 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." ; oboInOwl:hasAlternativeId "GO:0044086" ; oboInOwl:hasExactSynonym "vacuole organisation" ; oboInOwl:hasNarrowSynonym "vacuolar assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "vacuole biogenesis", "vacuole organization and biogenesis" ; oboInOwl:id "GO:0007033" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "vacuole organization" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0007039 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "vacuolar protein breakdown", "vacuolar protein catabolic process", "vacuolar protein catabolism", "vacuolar protein degradation" ; oboInOwl:id "GO:0007039" ; a owl:Class ; rdfs:label "protein catabolic process in the vacuole" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0030163, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030163 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0007040 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases." ; oboInOwl:hasExactSynonym "lysosome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lysosome organization and biogenesis" ; oboInOwl:id "GO:0007040" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "lysosome organization" ; rdfs:subClassOf obo:GO_0080171 . obo:GO_0007049 obo:IAO_0000115 "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division." ; oboInOwl:hasDbXref "Wikipedia:Cell_cycle" ; oboInOwl:hasExactSynonym "cell-division cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007049" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "cell cycle" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0007051 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart." ; oboInOwl:hasAlternativeId "GO:0043146" ; oboInOwl:hasExactSynonym "spindle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "spindle organization and biogenesis", "spindle stabilization" ; oboInOwl:id "GO:0007051" ; a owl:Class ; rdfs:label "spindle organization" ; rdfs:subClassOf obo:GO_0000226, obo:GO_0022402 . obo:GO_0007052 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/15341"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0000071", "GO:0030472", "GO:0043148" ; oboInOwl:hasExactSynonym "mitotic spindle organisation", "spindle organization and biogenesis during mitosis" ; oboInOwl:hasNarrowSynonym "mitotic spindle organisation in nucleus", "mitotic spindle organization and biogenesis in cell nucleus", "mitotic spindle organization and biogenesis in nucleus", "mitotic spindle organization in nucleus", "spindle organization and biogenesis in nucleus during mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic spindle organization and biogenesis", "mitotic spindle stabilization" ; oboInOwl:id "GO:0007052" ; a owl:Class ; rdfs:comment "In fission yeast most mitotic spindle organization occurs in the nucleus." ; rdfs:label "mitotic spindle organization" ; rdfs:subClassOf obo:GO_0007051, obo:GO_1902850 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007051 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007053 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007053" ; a owl:Class ; rdfs:label "spindle assembly involved in male meiosis" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0090306, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ) ] . obo:GO_0007054 obo:IAO_0000115 "The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "male meiosis I spindle assembly" ; oboInOwl:id "GO:0007054" ; a owl:Class ; rdfs:label "spindle assembly involved in male meiosis I" ; rdfs:subClassOf obo:GO_0007053, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007141 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007141 ] ) ] . obo:GO_0007056 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "female meiotic spindle assembly" ; oboInOwl:id "GO:0007056" ; a owl:Class ; rdfs:label "spindle assembly involved in female meiosis" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0090306, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ) ] . obo:GO_0007057 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "female meiosis I spindle assembly" ; oboInOwl:id "GO:0007057" ; a owl:Class ; rdfs:label "spindle assembly involved in female meiosis I" ; rdfs:subClassOf obo:GO_0007056, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007144 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007144 ] ) ] . obo:GO_0007059 obo:IAO_0000115 "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." ; oboInOwl:hasDbXref "Wikipedia:Chromosome_segregation" ; oboInOwl:hasExactSynonym "chromosome division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosome transmission" ; oboInOwl:id "GO:0007059" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "chromosome segregation" ; rdfs:subClassOf obo:GO_0022402 . obo:GO_0007060 obo:IAO_0000115 "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007060" ; a owl:Class ; rdfs:label "male meiosis chromosome segregation" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0045132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] . obo:GO_0007076 obo:IAO_0000115 "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007076" ; a owl:Class ; rdfs:label "mitotic chromosome condensation" ; rdfs:subClassOf obo:GO_0030261, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030261 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007077 obo:IAO_0000115 "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis." ; oboInOwl:hasBroadSynonym "NEB", "local NEB", "nuclear envelope breakdown" ; oboInOwl:hasExactSynonym "mitotic nuclear envelope breakdown" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic nuclear envelope catabolism", "mitotic nuclear envelope degradation", "mitotic nuclear envelope disassembly" ; oboInOwl:id "GO:0007077" ; a owl:Class ; rdfs:label "mitotic nuclear membrane disassembly" ; rdfs:subClassOf obo:GO_0051081, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051081 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007080 obo:IAO_0000115 "A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25547"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007080" ; a owl:Class ; rdfs:label "mitotic metaphase chromosome alignment" ; rdfs:subClassOf obo:GO_0051310, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051310 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007084 obo:IAO_0000115 "The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19950"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/20636"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "nuclear envelope repair", "nuclear envelope resealing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic nuclear envelope reassembly" ; oboInOwl:id "GO:0007084" ; a owl:Class ; rdfs:label "mitotic nuclear membrane reassembly" ; rdfs:subClassOf obo:GO_0031468, obo:GO_0101024 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031468 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007088 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitosis." ; oboInOwl:hasExactSynonym "regulation of mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007088" ; a owl:Class ; rdfs:label "regulation of mitotic nuclear division" ; rdfs:subClassOf obo:GO_0007346, obo:GO_0010564, obo:GO_0051783, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0007091 obo:IAO_0000115 "The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24140"^^xsd:anyURI ; oboInOwl:hasExactSynonym "metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process", "mitotic metaphase/anaphase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007091" ; a owl:Class ; rdfs:label "metaphase/anaphase transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0044772, obo:GO_0044784 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044784 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007093 obo:IAO_0000115 "A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0031575", "GO:0071780", "GO:0072413", "GO:0072456", "GO:0072474" ; oboInOwl:hasExactSynonym "mitotic cell cycle checkpoint", "signal transduction involved in mitotic cell cycle checkpoint" ; oboInOwl:hasNarrowSynonym "signal transduction involved in mitotic G2/M transition checkpoint", "signal transduction involved in mitotic cell cycle G1/S checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic checkpoint" ; oboInOwl:id "GO:0007093" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "mitotic cell cycle checkpoint signaling" ; rdfs:subClassOf obo:GO_0000075, obo:GO_0045930, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000075 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007094 obo:IAO_0000115 "A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signaling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19810"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/24179"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0044810", "GO:0072480", "GO:1902420" ; oboInOwl:hasExactSynonym "mitotic cell cycle spindle assembly checkpoint", "mitotic checkpoint", "mitotic spindle assembly checkpoint", "mitotic spindle assembly checkpoint signalling", "signal transduction involved in mitotic cell cycle spindle assembly checkpoint", "signal transduction involved in mitotic spindle assembly checkpoint" ; oboInOwl:hasNarrowSynonym "Dma1-dependent checkpoint", "Mad2-dependent checkpoint", "SAC-independent checkpoint", "signal transduction involved in Dma1-dependent checkpoint", "signal transduction involved in SAC-independent checkpoint", "signaling cascade involved in Dma1-dependent checkpoint", "signaling cascade involved in SAC-independent checkpoint", "signalling cascade involved in Dma1-dependent checkpoint", "signalling cascade involved in SAC-independent checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "signaling pathway involved in Dma1-dependent checkpoint", "signaling pathway involved in SAC-independent checkpoint", "signalling pathway involved in Dma1-dependent checkpoint", "signalling pathway involved in SAC-independent checkpoint" ; oboInOwl:id "GO:0007094" ; a owl:Class ; rdfs:label "mitotic spindle assembly checkpoint signaling" ; rdfs:subClassOf obo:GO_0045841, obo:GO_0071173, obo:GO_0071174 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071173 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007097 obo:IAO_0000115 "The directed movement of the nucleus to a specific location within a cell." ; oboInOwl:hasAlternativeId "GO:0040023" ; oboInOwl:hasExactSynonym "establishment of position of nucleus", "nuclear movement", "nuclear positioning", "nucleus migration", "nucleus positioning", "positioning of nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "establishment of cell nucleus localization", "establishment of localization of nucleus", "establishment of nucleus localisation", "establishment of nucleus localization" ; oboInOwl:id "GO:0007097" ; a owl:Class ; rdfs:label "nuclear migration" ; rdfs:subClassOf obo:GO_0046907, obo:GO_0051647, obo:GO_0051656 . obo:GO_0007112 obo:IAO_0000115 "A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells." ; oboInOwl:hasExactSynonym "cytokinesis after male meiosis", "cytokinesis involved in male meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007112" ; a owl:Class ; rdfs:label "male meiosis cytokinesis" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0033206, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000910 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ) ] . obo:GO_0007127 obo:IAO_0000115 "The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei." ; oboInOwl:hasDbXref "Wikipedia:Meiosis#Meiosis_I" ; oboInOwl:hasExactSynonym "meiosis I nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007127" ; a owl:Class ; rdfs:label "meiosis I" ; rdfs:subClassOf obo:GO_0061982, obo:GO_0140013, [ a owl:Restriction ; owl:onProperty obo:RO_0002093 ; owl:someValuesFrom obo:GO_0007134 ] . obo:GO_0007129 obo:IAO_0000115 "The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete." ; oboInOwl:hasDbXref "Wikipedia:Synapsis" ; oboInOwl:hasNarrowSynonym "chromosomal synapsis", "synapsis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosomal pairing" ; oboInOwl:id "GO:0007129" ; a owl:Class ; rdfs:label "homologous chromosome pairing at meiosis" ; rdfs:subClassOf obo:GO_0070192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045143 ] . obo:GO_0007134 obo:IAO_0000115 "The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007134" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiotic telophase I" ; rdfs:subClassOf obo:GO_0051326, obo:GO_0098764 . obo:GO_0007140 obo:IAO_0000115 "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasBroadSynonym "male nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "male meiosis" ; oboInOwl:id "GO:0007140" ; a owl:Class ; rdfs:label "male meiotic nuclear division" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0140013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048232 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000280 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048232 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007141 obo:IAO_0000115 "A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline." ; oboInOwl:hasExactSynonym "male meiosis I nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007141" ; a owl:Class ; rdfs:label "male meiosis I" ; rdfs:subClassOf obo:GO_0007127, obo:GO_0007140 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007127 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048232 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007143 obo:IAO_0000115 "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasBroadSynonym "female meiosis", "female meiotic division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007143" ; a owl:Class ; rdfs:comment "Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'." ; rdfs:label "female meiotic nuclear division" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0140013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000280 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007144 obo:IAO_0000115 "The cell cycle process in which the first meiotic division occurs in the female germline." ; oboInOwl:hasExactSynonym "female meiosis I nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007144" ; a owl:Class ; rdfs:label "female meiosis I" ; rdfs:subClassOf obo:GO_0007127, obo:GO_0007143 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007127 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0007154 obo:IAO_0000115 "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:hasDbXref "Wikipedia:Cell_signaling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007154" ; oboInOwl:inSubset go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "cell communication" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0007155 obo:IAO_0000115 "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2014-04-15T15:59:10Z" ; oboInOwl:hasAlternativeId "GO:0098602" ; oboInOwl:hasDbXref "Wikipedia:Cell_adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell adhesion molecule activity", "single organism cell adhesion" ; oboInOwl:id "GO:0007155" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "cell adhesion" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0007162 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion." ; oboInOwl:hasExactSynonym "down regulation of cell adhesion", "down-regulation of cell adhesion", "downregulation of cell adhesion" ; oboInOwl:hasNarrowSynonym "inhibition of cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell adhesion receptor inhibitor activity" ; oboInOwl:id "GO:0007162" ; a owl:Class ; rdfs:label "negative regulation of cell adhesion" ; rdfs:subClassOf obo:GO_0030155, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007155 ] ) ] . obo:GO_0007163 obo:IAO_0000115 "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." ; oboInOwl:hasAlternativeId "GO:0030012", "GO:0030467" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell polarity", "establishment and/or maintenance of cell polarity", "establishment and/or maintenance of cell polarization" ; oboInOwl:id "GO:0007163" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "establishment or maintenance of cell polarity" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0007165 obo:IAO_0000115 "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell." ; oboInOwl:hasAlternativeId "GO:0023014", "GO:0023015", "GO:0023016", "GO:0023033", "GO:0023045" ; oboInOwl:hasDbXref "Wikipedia:Signal_transduction" ; oboInOwl:hasNarrowSynonym "signal transduction by cis-phosphorylation", "signal transduction by conformational transition", "signal transduction by protein phosphorylation", "signal transduction by trans-phosphorylation", "signaling cascade", "signalling cascade" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "signaling pathway", "signalling pathway" ; oboInOwl:id "GO:0007165" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not." ; rdfs:label "signal transduction" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007154 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0023052 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051716 ] . obo:GO_0007267 obo:IAO_0000115 "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions." ; oboInOwl:hasExactSynonym "cell-cell signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007267" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_plant ; a owl:Class ; rdfs:label "cell-cell signaling" ; rdfs:subClassOf obo:GO_0007154, obo:GO_0023052 . obo:GO_0007268 obo:IAO_0000115 "The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; oboInOwl:hasBroadSynonym "signal transmission across a synapse", "synaptic transmission" ; oboInOwl:hasDbXref "Wikipedia:Neurotransmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neurotransmission" ; oboInOwl:id "GO:0007268" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "chemical synaptic transmission" ; rdfs:subClassOf obo:GO_0098916 . obo:GO_0007269 obo:IAO_0000115 "The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission." ; oboInOwl:hasAlternativeId "GO:0010554" ; oboInOwl:hasExactSynonym "neurotransmitter release", "neurotransmitter secretory pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007269" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin." ; rdfs:label "neurotransmitter secretion" ; rdfs:subClassOf obo:GO_0006836, obo:GO_0051649, obo:GO_0099643, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007268 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] . obo:GO_0007271 obo:IAO_0000115 "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; oboInOwl:hasExactSynonym "cholinergic synaptic transmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007271" ; a owl:Class ; rdfs:label "synaptic transmission, cholinergic" ; rdfs:subClassOf obo:GO_0007268 . obo:GO_0007274 obo:IAO_0000115 "The process of synaptic transmission from a neuron to a muscle, across a synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007274" ; a owl:Class ; rdfs:label "neuromuscular synaptic transmission" ; rdfs:subClassOf obo:GO_0007268 . obo:GO_0007275 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21234"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007275" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_chembl, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term was 'developmental process'." ; rdfs:label "multicellular organism development" ; rdfs:subClassOf obo:GO_0032501, obo:GO_0048856 . obo:GO_0007276 obo:IAO_0000115 "The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell." ; obo:RO_0002161 obo:NCBITaxon_Union_0000023 ; oboInOwl:hasAlternativeId "GO:0009552" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "gametogenesis" ; oboInOwl:id "GO:0007276" ; a owl:Class ; rdfs:label "gamete generation" ; rdfs:subClassOf obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019953 ] . obo:GO_0007281 obo:IAO_0000115 "The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism." ; oboInOwl:hasExactSynonym "germ-cell development" ; oboInOwl:hasNarrowSynonym "gametogenesis", "primordial germ cell development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007281" ; a owl:Class ; rdfs:label "germ cell development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007276 ] . obo:GO_0007283 obo:IAO_0000115 "The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa." ; oboInOwl:hasDbXref "Wikipedia:Spermatogenesis" ; oboInOwl:hasExactSynonym "generation of spermatozoa" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007283" ; a owl:Class ; rdfs:label "spermatogenesis" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0048232 . obo:GO_0007285 obo:IAO_0000115 "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007285" ; a owl:Class ; rdfs:label "primary spermatocyte growth" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0048588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007283 ] . obo:GO_0007286 obo:IAO_0000115 "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure." ; oboInOwl:hasDbXref "Wikipedia:Spermiogenesis" ; oboInOwl:hasExactSynonym "spermatid cell development", "spermiogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007286" ; a owl:Class ; rdfs:label "spermatid development" ; rdfs:subClassOf obo:GO_0007281, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048515 ] . obo:GO_0007289 obo:IAO_0000115 "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization." ; oboInOwl:hasExactSynonym "spermatid nuclear differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007289" ; a owl:Class ; rdfs:comment "See also the Cell Ontology term 'spermatid ; CL:0000018'." ; rdfs:label "spermatid nucleus differentiation" ; rdfs:subClassOf obo:GO_0006997, obo:GO_0022412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007286 ] . obo:GO_0007292 obo:IAO_0000115 "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007292" ; a owl:Class ; rdfs:label "female gamete generation" ; rdfs:subClassOf obo:GO_0007276 . obo:GO_0007296 obo:IAO_0000115 "The production of yolk. Yolk is a mixture of materials used for embryonic nutrition." ; oboInOwl:hasDbXref "Wikipedia:Vitellogenesis" ; oboInOwl:hasExactSynonym "yolk formation", "yolk production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007296" ; a owl:Class ; rdfs:label "vitellogenesis" ; rdfs:subClassOf obo:GO_0007028, obo:GO_0022412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] . obo:GO_0007320 obo:IAO_0000115 "The introduction of semen or sperm into the genital tract of a female." ; oboInOwl:hasDbXref "Wikipedia:Insemination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007320" ; a owl:Class ; rdfs:label "insemination" ; rdfs:subClassOf obo:GO_0044703, obo:GO_0044706, obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007620 ] . obo:GO_0007338 obo:IAO_0000115 "The union of male and female gametes to form a zygote." ; obo:RO_0002161 obo:NCBITaxon_58024 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "zygote biosynthesis", "zygote formation" ; oboInOwl:id "GO:0007338" ; a owl:Class ; rdfs:label "single fertilization" ; rdfs:subClassOf obo:GO_0009566 . obo:GO_0007346 obo:IAO_0000115 "Any process that modulates the rate or extent of progress through the mitotic cell cycle." ; oboInOwl:hasExactSynonym "mitotic cell cycle modulation", "mitotic cell cycle regulation", "modulation of mitotic cell cycle progression", "regulation of mitotic cell cycle progression", "regulation of progression through mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "mitotic cell cycle regulator" ; oboInOwl:id "GO:0007346" ; a owl:Class ; rdfs:label "regulation of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0051726, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0007369 obo:IAO_0000115 "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm." ; oboInOwl:hasDbXref "Wikipedia:Gastrulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007369" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "gastrulation" ; rdfs:subClassOf obo:GO_0048598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0001705 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0001706 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0001707 ] . obo:GO_0007398 obo:IAO_0000115 "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007398" ; a owl:Class ; rdfs:label "ectoderm development" ; rdfs:subClassOf obo:GO_0009888 . obo:GO_0007399 obo:IAO_0000115 "The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pan-neural process" ; oboInOwl:id "GO:0007399" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "nervous system development" ; rdfs:subClassOf obo:GO_0048731 . obo:GO_0007409 obo:IAO_0000115 "De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells." ; oboInOwl:hasAlternativeId "GO:0007410" ; oboInOwl:hasExactSynonym "axon morphogenesis", "neuron long process generation" ; oboInOwl:hasNarrowSynonym "axon growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007409" ; a owl:Class ; rdfs:comment "Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon)." ; rdfs:label "axonogenesis" ; rdfs:subClassOf obo:GO_0048812, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048667 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061564 ] . obo:GO_0007411 obo:IAO_0000115 "The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues." ; oboInOwl:hasAlternativeId "GO:0008040" ; oboInOwl:hasDbXref "Wikipedia:Axon_guidance" ; oboInOwl:hasExactSynonym "axon pathfinding" ; oboInOwl:hasNarrowSynonym "axon growth cone guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "axon chemotaxis" ; oboInOwl:id "GO:0007411" ; a owl:Class ; rdfs:label "axon guidance" ; rdfs:subClassOf obo:GO_0097485, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007409 ] . obo:GO_0007413 obo:IAO_0000115 "The collection of axons into a bundle of rods, known as a fascicle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "fasciculation of neuron" ; oboInOwl:id "GO:0007413" ; a owl:Class ; rdfs:label "axonal fasciculation" ; rdfs:subClassOf obo:GO_0008038, obo:GO_0106030, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061564 ] . obo:GO_0007416 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional)." ; oboInOwl:hasDbXref "Wikipedia:Synaptogenesis" ; oboInOwl:hasExactSynonym "synapse biogenesis", "synaptogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007416" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synapse assembly" ; rdfs:subClassOf obo:GO_0034329, obo:GO_0050808, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ] . obo:GO_0007492 obo:IAO_0000115 "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007492" ; a owl:Class ; rdfs:label "endoderm development" ; rdfs:subClassOf obo:GO_0009888 . obo:GO_0007498 obo:IAO_0000115 "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007498" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "mesoderm development" ; rdfs:subClassOf obo:GO_0009888 . obo:GO_0007517 obo:IAO_0000115 "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007517" ; a owl:Class ; rdfs:label "muscle organ development" ; rdfs:subClassOf obo:GO_0048513, obo:GO_0061061 . obo:GO_0007530 obo:IAO_0000115 "Any process that establishes and transmits the specification of sexual status of an individual organism." ; oboInOwl:hasDbXref "Wikipedia:Sex-determination_system" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007530" ; a owl:Class ; rdfs:label "sex determination" ; rdfs:subClassOf obo:GO_0003006 . obo:GO_0007548 obo:IAO_0000115 "The establishment of the sex of an organism by physical differentiation." ; oboInOwl:hasDbXref "Wikipedia:Sexual_differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007548" ; a owl:Class ; rdfs:label "sex differentiation" ; rdfs:subClassOf obo:GO_0003006 . obo:GO_0007549 obo:IAO_0000115 "Compensating for the variation in the unpaired sex chromosome:autosome chromosome ratios between sexes by activation or inactivation of genes on one or both of the sex chromosomes." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25961"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "dosage compensation" ; oboInOwl:hasDbXref "Wikipedia:Sex-chromosome_dosage_compensation" ; oboInOwl:hasExactSynonym "sex chromosome dosage compensation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007549" ; a owl:Class ; rdfs:label "sex-chromosome dosage compensation" ; rdfs:subClassOf obo:GO_0040029 . obo:GO_0007568 obo:IAO_0000115 "OBSOLETE. A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24930"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0016280" ; oboInOwl:hasExactSynonym "ageing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007568" ; a owl:Class ; rdfs:comment "The reason for obsoletion is that this represents a phenotype." ; rdfs:label "obsolete aging" ; owl:deprecated true . obo:GO_0007586 obo:IAO_0000115 "The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasDbXref "Wikipedia:Digestion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007586" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "digestion" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0007588 obo:IAO_0000115 "The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22368"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Excretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007588" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:label "excretion" ; rdfs:subClassOf obo:GO_0003008 . obo:GO_0007610 obo:IAO_0000115 "The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-20T14:06:08Z" ; oboInOwl:hasAlternativeId "GO:0023032", "GO:0044708", "GO:0044709" ; oboInOwl:hasDbXref "Wikipedia:Behavior" ; oboInOwl:hasExactSynonym "behavioral response to stimulus", "behaviour", "behavioural response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism behavior" ; oboInOwl:id "GO:0007610" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_agr, go:goslim_flybase_ribbon ; a owl:Class ; rdfs:comment """1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews. 2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis).""" ; rdfs:label "behavior" ; rdfs:subClassOf obo:GO_0032501 ; owl:disjointWith obo:GO_0032502 . obo:GO_0007611 obo:IAO_0000115 "The acquisition and processing of information and/or the storage and retrieval of this information over time." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007611" ; a owl:Class ; rdfs:label "learning or memory" ; rdfs:subClassOf obo:GO_0007610, obo:GO_0050890 . obo:GO_0007612 obo:IAO_0000115 "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience." ; oboInOwl:hasDbXref "Wikipedia:Learning" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007612" ; a owl:Class ; rdfs:label "learning" ; rdfs:subClassOf obo:GO_0007611 . obo:GO_0007613 obo:IAO_0000115 "The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task)." ; oboInOwl:hasDbXref "Wikipedia:Memory" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007613" ; a owl:Class ; rdfs:label "memory" ; rdfs:subClassOf obo:GO_0007611 . obo:GO_0007617 obo:IAO_0000115 "The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes." ; oboInOwl:hasDbXref "Wikipedia:Mating_behaviour" ; oboInOwl:hasExactSynonym "mating behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007617" ; a owl:Class ; rdfs:label "mating behavior" ; rdfs:subClassOf obo:GO_0019098 . obo:GO_0007618 obo:IAO_0000115 "The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007618" ; a owl:Class ; rdfs:label "mating" ; rdfs:subClassOf obo:GO_0044703, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019953 ] . obo:GO_0007620 obo:IAO_0000115 "The act of sexual union between male and female, involving the transfer of sperm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007620" ; a owl:Class ; rdfs:label "copulation" ; rdfs:subClassOf obo:GO_0007617 . obo:GO_0007622 obo:IAO_0000115 "The specific behavior of an organism that recur with measured regularity." ; oboInOwl:hasExactSynonym "rhythmic behavioral response to stimulus", "rhythmic behaviour", "rhythmic behavioural response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007622" ; a owl:Class ; rdfs:label "rhythmic behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0007623 obo:IAO_0000115 "Any biological process in an organism that recurs with a regularity of approximately 24 hours." ; oboInOwl:hasAlternativeId "GO:0050895" ; oboInOwl:hasDbXref "Wikipedia:Circadian_rhythm" ; oboInOwl:hasExactSynonym "circadian process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "circadian response", "response to circadian rhythm" ; oboInOwl:id "GO:0007623" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_plant ; a owl:Class ; rdfs:label "circadian rhythm" ; rdfs:subClassOf obo:GO_0048511 . obo:GO_0007624 obo:IAO_0000115 "The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007624" ; a owl:Class ; rdfs:label "ultradian rhythm" ; rdfs:subClassOf obo:GO_0048511 . obo:GO_0007626 obo:IAO_0000115 "The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions." ; oboInOwl:hasExactSynonym "behavior via locomotion", "locomotion in response to stimulus", "locomotory behavioral response to stimulus", "locomotory behaviour", "locomotory behavioural response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007626" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "locomotory behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0007631 obo:IAO_0000115 "Behavior associated with the intake of food." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/18547"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2011-10-27T03:53:33Z" ; oboInOwl:hasAlternativeId "GO:0044366", "GO:0044367", "GO:0044368", "GO:0044369", "GO:0044370", "GO:0044371", "GO:0044372" ; oboInOwl:hasDbXref "Wikipedia:List_of_feeding_behaviours" ; oboInOwl:hasExactSynonym "behavioral response to food", "behavioural response to food", "feeding behaviour" ; oboInOwl:hasNarrowSynonym "eating", "feeding from phloem of other organism", "feeding from plant phloem", "feeding from tissue of other organism", "feeding from vascular tissue of another organism", "feeding from xylem of other organism", "feeding on blood of other organism", "feeding on or from other organism", "feeding on plant sap", "hematophagy", "injection of substance into other organism during feeding on blood of other organism", "taking of blood meal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007631" ; a owl:Class ; rdfs:comment "See also the biological process term 'behavior ; GO:0007610'." ; rdfs:label "feeding behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0007635 obo:IAO_0000115 "Behavior that is dependent upon the sensation of chemicals." ; oboInOwl:hasExactSynonym "behavioral response to chemical stimulus", "behavioural response to chemical stimulus", "chemosensory behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0007635" ; a owl:Class ; rdfs:label "chemosensory behavior" ; rdfs:subClassOf obo:GO_0007610, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042221 ] . obo:GO_0008021 obo:IAO_0000115 "A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1071221672", "Wikipedia:Synaptic_vesicle" ; oboInOwl:hasNarrowSynonym "docked vesicle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0008021" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "This term should not be confused with GO:0097547 'synaptic vesicle protein transport vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles." ; rdfs:label "synaptic vesicle" ; rdfs:subClassOf obo:GO_0070382, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] . obo:GO_0008037 obo:IAO_0000115 "The process in which a cell in an organism interprets its surroundings." ; oboInOwl:hasExactSynonym "recognition of surroundings by cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008037" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cell recognition" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0008038 obo:IAO_0000115 "The process in which a neuronal cell in a multicellular organism interprets its surroundings." ; oboInOwl:hasExactSynonym "neuronal cell recognition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008038" ; a owl:Class ; rdfs:label "neuron recognition" ; rdfs:subClassOf obo:GO_0008037, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ] . obo:GO_0008088 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules in neuron projections." ; oboInOwl:hasDbXref "Wikipedia:Axoplasmic_transport" ; oboInOwl:hasNarrowSynonym "axon cargo transport", "axonal transport", "axoplasmic transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008088" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "axo-dendritic transport" ; rdfs:subClassOf obo:GO_0010970, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043005 ] . obo:GO_0008089 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons." ; oboInOwl:hasExactSynonym "anterograde axon cargo transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008089" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "anterograde axonal transport" ; rdfs:subClassOf obo:GO_0098930, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_1904115 ] . obo:GO_0008104 obo:IAO_0000115 "Any process in which a protein is transported to, or maintained in, a specific location." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0008105", "GO:0016249", "GO:0034613" ; oboInOwl:hasExactSynonym "cellular protein localisation", "cellular protein localization", "protein localisation" ; oboInOwl:hasNarrowSynonym "channel localizer activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "asymmetric protein localisation", "asymmetric protein localization", "establishment and maintenance of asymmetric protein localization", "establishment and maintenance of protein localization" ; oboInOwl:id "GO:0008104" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "protein localization" ; rdfs:subClassOf obo:GO_0070727 . obo:GO_0008150 obo:IAO_0000115 "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24968"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T15:05:24Z" ; oboInOwl:hasAlternativeId "GO:0000004", "GO:0007582", "GO:0044699" ; oboInOwl:hasDbXref "Wikipedia:Biological_process" ; oboInOwl:hasExactSynonym "biological process", "physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism process", "single-organism process" ; oboInOwl:id "GO:0008150" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that, in addition to forming the root of the biological process ontology, this term is recommended for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.", "Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this." ; rdfs:label "biological_process" . obo:GO_0008152 obo:IAO_0000115 "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-10-17T15:46:40Z" ; oboInOwl:hasAlternativeId "GO:0044236", "GO:0044710" ; oboInOwl:hasDbXref "Wikipedia:Metabolism" ; oboInOwl:hasExactSynonym "metabolism" ; oboInOwl:hasNarrowSynonym "metabolic process resulting in cell growth", "metabolism resulting in cell growth", "multicellular organism metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism metabolic process" ; oboInOwl:id "GO:0008152" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_chembl, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions." ; rdfs:label "metabolic process" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848, obo:GO_0051179 . obo:GO_0008156 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication." ; oboInOwl:hasExactSynonym "down regulation of DNA replication", "down-regulation of DNA replication", "downregulation of DNA replication" ; oboInOwl:hasNarrowSynonym "inhibition of DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA replication inhibitor" ; oboInOwl:id "GO:0008156" ; a owl:Class ; rdfs:label "negative regulation of DNA replication" ; rdfs:subClassOf obo:GO_0006275, obo:GO_0051053, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006260 ] ) ] . obo:GO_0008213 obo:IAO_0000115 "The addition of an alkyl group to a protein amino acid. Alkyl groups are derived from alkanes by removal of one hydrogen atom." ; oboInOwl:hasExactSynonym "protein amino acid alkylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008213" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_yeast ; a owl:Class ; rdfs:label "protein alkylation" ; rdfs:subClassOf obo:GO_0036211 . obo:GO_0008219 obo:IAO_0000115 "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24680"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "accidental cell death", "necrosis" ; oboInOwl:id "GO:0008219" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms." ; rdfs:label "cell death" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0008283 obo:IAO_0000115 "The multiplication or reproduction of cells, resulting in the expansion of a cell population." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell proliferation" ; oboInOwl:id "GO:0008283" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir ; a owl:Class ; rdfs:comment "This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms." ; rdfs:label "cell population proliferation" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0008284 obo:IAO_0000115 "Any process that activates or increases the rate or extent of cell proliferation." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasExactSynonym "up regulation of cell proliferation", "up-regulation of cell proliferation", "upregulation of cell proliferation" ; oboInOwl:hasNarrowSynonym "activation of cell proliferation", "stimulation of cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cell proliferation" ; oboInOwl:id "GO:0008284" ; a owl:Class ; rdfs:label "positive regulation of cell population proliferation" ; rdfs:subClassOf obo:GO_0042127, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008283 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008283 ] ) ] . obo:GO_0008285 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of cell proliferation." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasExactSynonym "down regulation of cell proliferation", "down-regulation of cell proliferation", "downregulation of cell proliferation" ; oboInOwl:hasNarrowSynonym "inhibition of cell proliferation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell proliferation" ; oboInOwl:id "GO:0008285" ; a owl:Class ; rdfs:label "negative regulation of cell population proliferation" ; rdfs:subClassOf obo:GO_0042127, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008283 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008283 ] ) ] . obo:GO_0008291 obo:IAO_0000115 "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ; oboInOwl:hasExactSynonym "acetylcholine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008291" ; a owl:Class ; rdfs:label "acetylcholine metabolic process" ; rdfs:subClassOf obo:GO_1900619, obo:GO_1901564 . obo:GO_0008306 obo:IAO_0000115 "Learning by associating a stimulus (the cause) with a particular outcome (the effect)." ; oboInOwl:hasDbXref "Wikipedia:Learning#Associative_learning" ; oboInOwl:hasExactSynonym "Pavlovian conditioning", "classical conditioning", "conditional learning", "conditional response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008306" ; a owl:Class ; rdfs:label "associative learning" ; rdfs:subClassOf obo:GO_0007612 . obo:GO_0008354 obo:IAO_0000115 "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form." ; oboInOwl:hasExactSynonym "germ-cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "primordial germ cell migration" ; oboInOwl:id "GO:0008354" ; a owl:Class ; rdfs:label "germ cell migration" ; rdfs:subClassOf obo:GO_0016477, obo:GO_0022412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007276 ] . obo:GO_0008356 obo:IAO_0000115 "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity." ; oboInOwl:hasDbXref "Wikipedia:Asymmetric_cell_division" ; oboInOwl:hasExactSynonym "asymmetrical cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "asymmetric cytokinesis", "asymmetrical cytokinesis" ; oboInOwl:id "GO:0008356" ; a owl:Class ; rdfs:label "asymmetric cell division" ; rdfs:subClassOf obo:GO_0051301 . obo:GO_0008361 obo:IAO_0000115 "Any process that modulates the size of a cell." ; oboInOwl:hasExactSynonym "cell size control" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008361" ; a owl:Class ; rdfs:label "regulation of cell size" ; rdfs:subClassOf obo:GO_0032535 . obo:GO_0008380 obo:IAO_0000115 "The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." ; oboInOwl:hasAlternativeId "GO:0006395" ; oboInOwl:hasDbXref "Wikipedia:RNA_splicing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pre-mRNA splicing factor activity" ; oboInOwl:id "GO:0008380" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "RNA splicing" ; rdfs:subClassOf obo:GO_0006396 . obo:GO_0008406 obo:IAO_0000115 "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones." ; oboInOwl:hasExactSynonym "gonadogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008406" ; a owl:Class ; rdfs:label "gonad development" ; rdfs:subClassOf obo:GO_0048513, obo:GO_0048608, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045137 ] . obo:GO_0008584 obo:IAO_0000115 "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure." ; oboInOwl:hasExactSynonym "testicular development", "testis development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008584" ; a owl:Class ; rdfs:label "male gonad development" ; rdfs:subClassOf obo:GO_0008406, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046546 ] . obo:GO_0008610 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent." ; oboInOwl:hasExactSynonym "lipid anabolism", "lipid biosynthesis", "lipid formation", "lipid synthesis", "lipogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0008610" ; a owl:Class ; rdfs:label "lipid biosynthetic process" ; rdfs:subClassOf obo:GO_0006629, obo:GO_1901576 . obo:GO_0008630 obo:IAO_0000115 "The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA damage response, signal transduction resulting in induction of apoptosis" ; oboInOwl:id "GO:0008630" ; a owl:Class ; rdfs:label "intrinsic apoptotic signaling pathway in response to DNA damage" ; rdfs:subClassOf obo:GO_0006974, obo:GO_0097193 . obo:GO_0009056 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-10-17T15:52:35Z" ; oboInOwl:hasAlternativeId "GO:0044243", "GO:0044712" ; oboInOwl:hasDbXref "Wikipedia:Catabolism" ; oboInOwl:hasExactSynonym "breakdown", "catabolism", "degradation" ; oboInOwl:hasNarrowSynonym "multicellular organismal catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism catabolic process" ; oboInOwl:id "GO:0009056" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_plant ; a owl:Class ; rdfs:label "catabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0009057 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasAlternativeId "GO:0043285", "GO:0044266" ; oboInOwl:hasExactSynonym "biopolymer catabolic process", "macromolecule breakdown", "macromolecule catabolism", "macromolecule degradation" ; oboInOwl:hasNarrowSynonym "multicellular organismal macromolecule catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular macromolecule catabolic process", "cellular macromolecule catabolism", "cellular macromolecule degradation" ; oboInOwl:id "GO:0009057" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "macromolecule catabolic process" ; rdfs:subClassOf obo:GO_0043170, obo:GO_1901575 . obo:GO_0009058 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-10-17T15:52:18Z" ; oboInOwl:hasAlternativeId "GO:0044274", "GO:0044711" ; oboInOwl:hasBroadSynonym "formation" ; oboInOwl:hasDbXref "Wikipedia:Anabolism" ; oboInOwl:hasExactSynonym "anabolism", "biosynthesis", "synthesis" ; oboInOwl:hasNarrowSynonym "multicellular organismal biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism biosynthetic process" ; oboInOwl:id "GO:0009058" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:label "biosynthetic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0009059 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/15249"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/25418"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0043284" ; oboInOwl:hasExactSynonym "biopolymer biosynthetic process", "macromolecule anabolism", "macromolecule biosynthesis", "macromolecule formation", "macromolecule synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009059" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "macromolecule biosynthetic process" ; rdfs:subClassOf obo:GO_0043170, obo:GO_0044249, obo:GO_1901576 . obo:GO_0009266 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus." ; oboInOwl:hasExactSynonym "response to thermal stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009266" ; a owl:Class ; rdfs:label "response to temperature stimulus" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0009268 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009268" ; a owl:Class ; rdfs:label "response to pH" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0009269 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "desiccation tolerance" ; oboInOwl:id "GO:0009269" ; a owl:Class ; rdfs:label "response to desiccation" ; rdfs:subClassOf obo:GO_0009414 . obo:GO_0009295 obo:IAO_0000115 "The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined." ; oboInOwl:hasDbXref "Wikipedia:Nucleoid" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0009295" ; a owl:Class ; rdfs:label "nucleoid" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0009299 obo:IAO_0000115 "The cellular synthesis of messenger RNA (mRNA) from a DNA template." ; oboInOwl:hasAlternativeId "GO:0061023" ; oboInOwl:hasBroadSynonym "mRNA biosynthesis", "mRNA biosynthetic process", "mRNA synthesis" ; oboInOwl:hasExactSynonym "cellular mRNA transcription" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009299" ; a owl:Class ; rdfs:label "mRNA transcription" ; rdfs:subClassOf obo:GO_0006351, obo:GO_0016071 . obo:GO_0009306 obo:IAO_0000115 "The controlled release of proteins from a cell." ; oboInOwl:hasAlternativeId "GO:0045166", "GO:0045731" ; oboInOwl:hasNarrowSynonym "glycoprotein secretion", "protein secretion during cell fate commitment", "protein secretion resulting in cell fate commitment" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009306" ; a owl:Class ; rdfs:label "protein secretion" ; rdfs:subClassOf obo:GO_0015031, obo:GO_0032940, obo:GO_0035592 . obo:GO_0009308 obo:IAO_0000115 "The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2009-07-15T11:55:44Z" ; oboInOwl:hasAlternativeId "GO:0044106" ; oboInOwl:hasExactSynonym "amine metabolism", "cellular amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009308" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "amine metabolic process" ; rdfs:subClassOf obo:GO_1901564 . obo:GO_0009309 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ; oboInOwl:hasExactSynonym "amine anabolism", "amine biosynthesis", "amine formation", "amine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009309" ; a owl:Class ; rdfs:label "amine biosynthetic process" ; rdfs:subClassOf obo:GO_0009308, obo:GO_0044271, obo:GO_1901566 . obo:GO_0009310 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom." ; oboInOwl:hasExactSynonym "amine breakdown", "amine catabolism", "amine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009310" ; a owl:Class ; rdfs:label "amine catabolic process" ; rdfs:subClassOf obo:GO_0009308, obo:GO_1901565 . obo:GO_0009314 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." ; oboInOwl:hasExactSynonym "response to electromagnetic radiation stimulus", "response to radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009314" ; a owl:Class ; rdfs:comment "Note that 'radiation' refers to electromagnetic radiation of any wavelength." ; rdfs:label "response to radiation" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0009408 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism." ; oboInOwl:hasAlternativeId "GO:0006951" ; oboInOwl:hasNarrowSynonym "response to heat shock" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009408" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "response to heat" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0009266 . obo:GO_0009411 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." ; oboInOwl:hasExactSynonym "response to UV light stimulus", "response to UV radiation stimulus", "response to ultraviolet light stimulus", "response to ultraviolet radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009411" ; a owl:Class ; rdfs:label "response to UV" ; rdfs:subClassOf obo:GO_0009416 . obo:GO_0009414 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water." ; oboInOwl:hasExactSynonym "response to dehydration", "response to drought", "response to thirst" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "drought tolerance" ; oboInOwl:id "GO:0009414" ; a owl:Class ; rdfs:label "response to water deprivation" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0009415 . obo:GO_0009415 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water." ; oboInOwl:hasExactSynonym "response to water stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009415" ; a owl:Class ; rdfs:label "response to water" ; rdfs:subClassOf obo:GO_0001101, obo:GO_0009628, obo:GO_0010033, obo:GO_0010035, obo:GO_1901700, obo:GO_1902074 . obo:GO_0009416 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009416" ; oboInOwl:inSubset go:goslim_plant ; a owl:Class ; rdfs:label "response to light stimulus" ; rdfs:subClassOf obo:GO_0009314 . obo:GO_0009453 obo:IAO_0000115 "The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates." ; oboInOwl:hasExactSynonym "energytaxis", "taxis in response to energy source" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009453" ; a owl:Class ; rdfs:label "energy taxis" ; rdfs:subClassOf obo:GO_0042330 . obo:GO_0009566 obo:IAO_0000115 "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20176"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Fertilisation" ; oboInOwl:hasExactSynonym "syngamy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009566" ; a owl:Class ; rdfs:label "fertilization" ; rdfs:subClassOf obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019953 ] . obo:GO_0009605 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus." ; oboInOwl:hasExactSynonym "response to environmental stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009605" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_drosophila, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to external stimulus" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0009607 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." ; oboInOwl:hasNarrowSynonym "response to biotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009607" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to biotic stimulus" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0009611 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism." ; oboInOwl:hasAlternativeId "GO:0002245" ; oboInOwl:hasExactSynonym "physiological response to wounding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009611" ; a owl:Class ; rdfs:label "response to wounding" ; rdfs:subClassOf obo:GO_0006950 . obo:GO_0009628 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/16572"^^xsd:anyURI ; oboInOwl:hasNarrowSynonym "response to abiotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009628" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_metagenomics, go:goslim_plant ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to abiotic stimulus" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0009629 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus." ; oboInOwl:hasExactSynonym "response to gravitational stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009629" ; a owl:Class ; rdfs:label "response to gravity" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0009636 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus." ; oboInOwl:hasNarrowSynonym "detoxification response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "toxin resistance", "toxin susceptibility/resistance" ; oboInOwl:id "GO:0009636" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "response to toxic substance" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0009653 obo:IAO_0000115 "The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form." ; oboInOwl:hasBroadSynonym "embryogenesis and morphogenesis" ; oboInOwl:hasDbXref "Wikipedia:Morphogenesis" ; oboInOwl:hasExactSynonym "anatomical structure organization", "morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009653" ; a owl:Class ; rdfs:label "anatomical structure morphogenesis" ; rdfs:subClassOf obo:GO_0032502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048856 ] . obo:GO_0009712 obo:IAO_0000115 "The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "catechol metabolic process", "catechol metabolism" ; oboInOwl:id "GO:0009712" ; a owl:Class ; rdfs:label "catechol-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0018958 . obo:GO_0009713 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "catechol anabolism", "catechol biosynthesis", "catechol biosynthetic process", "catechol formation", "catechol synthesis" ; oboInOwl:id "GO:0009713" ; a owl:Class ; rdfs:label "catechol-containing compound biosynthetic process" ; rdfs:subClassOf obo:GO_0009712, obo:GO_0046189 . obo:GO_0009786 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of asymmetric cell division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009786" ; a owl:Class ; rdfs:label "regulation of asymmetric cell division" ; rdfs:subClassOf obo:GO_0051302, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008356 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008356 ] ) ] . obo:GO_0009790 obo:IAO_0000115 "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant." ; oboInOwl:hasAlternativeId "GO:0009795" ; oboInOwl:hasBroadSynonym "embryogenesis and morphogenesis" ; oboInOwl:hasDbXref "Wikipedia:Embryogenesis" ; oboInOwl:hasExactSynonym "embryogenesis", "embryonal development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009790" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_chembl, go:goslim_plant ; a owl:Class ; rdfs:label "embryo development" ; rdfs:subClassOf obo:GO_0007275 . obo:GO_0009791 obo:IAO_0000115 "The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009791" ; oboInOwl:inSubset go:goslim_plant ; a owl:Class ; rdfs:label "post-embryonic development" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0009888 obo:IAO_0000115 "The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure." ; obo:RO_0002161 obo:NCBITaxon_147554, obo:NCBITaxon_33630, obo:NCBITaxon_33682, obo:NCBITaxon_38254, obo:NCBITaxon_4891 ; oboInOwl:hasBroadSynonym "histogenesis and organogenesis" ; oboInOwl:hasDbXref "Wikipedia:Histogenesis" ; oboInOwl:hasExactSynonym "histogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009888" ; a owl:Class ; rdfs:label "tissue development" ; rdfs:subClassOf obo:GO_0048856 . obo:GO_0009889 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ; oboInOwl:hasExactSynonym "regulation of anabolism", "regulation of biosynthesis", "regulation of formation", "regulation of synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009889" ; a owl:Class ; rdfs:label "regulation of biosynthetic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009058 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009058 ] ) ] . obo:GO_0009890 obo:IAO_0000115 "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances." ; oboInOwl:hasExactSynonym "down regulation of biosynthetic process", "down-regulation of biosynthetic process", "downregulation of biosynthetic process", "negative regulation of anabolism", "negative regulation of biosynthesis", "negative regulation of formation", "negative regulation of synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009890" ; a owl:Class ; rdfs:label "negative regulation of biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0009892, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009058 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009058 ] ) ] . obo:GO_0009891 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances." ; oboInOwl:hasExactSynonym "positive regulation of anabolism", "positive regulation of biosynthesis", "positive regulation of formation", "positive regulation of synthesis", "up regulation of biosynthetic process", "up-regulation of biosynthetic process", "upregulation of biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of biosynthetic process", "stimulation of biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009891" ; a owl:Class ; rdfs:label "positive regulation of biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0009893, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009058 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009058 ] ) ] . obo:GO_0009892 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ; oboInOwl:hasAlternativeId "GO:0044252" ; oboInOwl:hasExactSynonym "down regulation of metabolic process", "down-regulation of metabolic process", "downregulation of metabolic process", "negative regulation of metabolism", "negative regulation of organismal metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of metabolic process", "inhibition of organismal metabolic process", "negative regulation of multicellular organismal metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009892" ; a owl:Class ; rdfs:label "negative regulation of metabolic process" ; rdfs:subClassOf obo:GO_0019222, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008152 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008152 ] ) ] . obo:GO_0009893 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ; oboInOwl:hasAlternativeId "GO:0044253" ; oboInOwl:hasExactSynonym "positive regulation of metabolism", "up regulation of metabolic process", "up-regulation of metabolic process", "upregulation of metabolic process" ; oboInOwl:hasNarrowSynonym "activation of metabolic process", "positive regulation of multicellular organismal metabolic process", "positive regulation of organismal metabolism", "stimulation of metabolic process", "stimulation of organismal metabolic process", "up-regulation of organismal metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009893" ; a owl:Class ; rdfs:label "positive regulation of metabolic process" ; rdfs:subClassOf obo:GO_0019222, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008152 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008152 ] ) ] . obo:GO_0009894 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances." ; oboInOwl:hasExactSynonym "regulation of breakdown", "regulation of catabolism", "regulation of degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009894" ; a owl:Class ; rdfs:label "regulation of catabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009056 ] ) ] . obo:GO_0009895 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." ; oboInOwl:hasExactSynonym "down regulation of catabolic process", "down-regulation of catabolic process", "downregulation of catabolic process", "negative regulation of breakdown", "negative regulation of catabolism", "negative regulation of degradation" ; oboInOwl:hasNarrowSynonym "inhibition of catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009895" ; a owl:Class ; rdfs:label "negative regulation of catabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0009894, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009056 ] ) ] . obo:GO_0009896 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances." ; oboInOwl:hasExactSynonym "positive regulation of breakdown", "positive regulation of catabolism", "positive regulation of degradation", "up regulation of catabolic process", "up-regulation of catabolic process", "upregulation of catabolic process" ; oboInOwl:hasNarrowSynonym "activation of catabolic process", "stimulation of catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009896" ; a owl:Class ; rdfs:label "positive regulation of catabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0009894, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009056 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009056 ] ) ] . obo:GO_0009966 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of signal transduction." ; oboInOwl:hasAlternativeId "GO:0035466" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of signaling pathway", "regulation of signalling pathway" ; oboInOwl:id "GO:0009966" ; a owl:Class ; rdfs:label "regulation of signal transduction" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0023051, obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007165 ] ) ] . obo:GO_0009967 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of signal transduction." ; oboInOwl:hasAlternativeId "GO:0035468" ; oboInOwl:hasExactSynonym "up regulation of signal transduction", "up-regulation of signal transduction", "upregulation of signal transduction" ; oboInOwl:hasNarrowSynonym "activation of signal transduction", "stimulation of signal transduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of signaling pathway", "positive regulation of signalling pathway" ; oboInOwl:id "GO:0009967" ; a owl:Class ; rdfs:label "positive regulation of signal transduction" ; rdfs:subClassOf obo:GO_0009966, obo:GO_0010647, obo:GO_0023056, obo:GO_0048584, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007165 ] ) ] . obo:GO_0009968 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction." ; oboInOwl:hasAlternativeId "GO:0035467" ; oboInOwl:hasExactSynonym "down regulation of signal transduction", "down-regulation of signal transduction", "downregulation of signal transduction" ; oboInOwl:hasNarrowSynonym "inhibition of signal transduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of signaling pathway", "negative regulation of signalling pathway" ; oboInOwl:id "GO:0009968" ; a owl:Class ; rdfs:label "negative regulation of signal transduction" ; rdfs:subClassOf obo:GO_0009966, obo:GO_0010648, obo:GO_0023057, obo:GO_0048585, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007165 ] ) ] . obo:GO_0009987 obo:IAO_0000115 "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-12-11T16:56:55Z" ; oboInOwl:hasAlternativeId "GO:0008151", "GO:0044763", "GO:0050875" ; oboInOwl:hasExactSynonym "cell physiology", "cellular physiological process" ; oboInOwl:hasNarrowSynonym "cell growth and/or maintenance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism cellular process" ; oboInOwl:id "GO:0009987" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_plant ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term." ; rdfs:label "cellular process" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0009991 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009991" ; a owl:Class ; rdfs:label "response to extracellular stimulus" ; rdfs:subClassOf obo:GO_0009605 . obo:GO_0009994 obo:IAO_0000115 "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete." ; oboInOwl:hasExactSynonym "oocyte cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009994" ; a owl:Class ; rdfs:label "oocyte differentiation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048477 ] . obo:GO_0009996 obo:IAO_0000115 "Any process that restricts, stops or prevents a cell from adopting a specific cell fate." ; oboInOwl:hasExactSynonym "down regulation of cell fate specification", "down-regulation of cell fate specification", "downregulation of cell fate specification", "suppression of cell fate" ; oboInOwl:hasNarrowSynonym "inhibition of cell fate specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0009996" ; a owl:Class ; rdfs:label "negative regulation of cell fate specification" ; rdfs:subClassOf obo:GO_0010454, obo:GO_0042659, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001708 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001708 ] ) ] . obo:GO_0010032 obo:IAO_0000115 "Compaction of chromatin structure prior to meiosis in eukaryotic cells." ; oboInOwl:hasExactSynonym "chromosome condensation involved in meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010032" ; a owl:Class ; rdfs:label "meiotic chromosome condensation" ; rdfs:subClassOf obo:GO_0030261, obo:GO_0070192 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030261 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0010033 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." ; oboInOwl:hasAlternativeId "GO:1990367" ; oboInOwl:hasNarrowSynonym "process resulting in tolerance to organic substance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010033" ; a owl:Class ; rdfs:label "response to organic substance" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0010035 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010035" ; a owl:Class ; rdfs:label "response to inorganic substance" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0010037 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010037" ; a owl:Class ; rdfs:label "response to carbon dioxide" ; rdfs:subClassOf obo:GO_0010033, obo:GO_1901700 . obo:GO_0010038 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus." ; oboInOwl:hasExactSynonym "response to metal" ; oboInOwl:hasNarrowSynonym "response to heavy metal" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heavy metal sensitivity/resistance" ; oboInOwl:id "GO:0010038" ; a owl:Class ; rdfs:label "response to metal ion" ; rdfs:subClassOf obo:GO_0010035 . obo:GO_0010042 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus." ; oboInOwl:hasExactSynonym "response to manganese" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010042" ; a owl:Class ; rdfs:label "response to manganese ion" ; rdfs:subClassOf obo:GO_0010038 . obo:GO_0010044 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus." ; oboInOwl:hasExactSynonym "response to aluminium ion", "response to aluminum" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010044" ; a owl:Class ; rdfs:label "response to aluminum ion" ; rdfs:subClassOf obo:GO_0010038 . obo:GO_0010165 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz)." ; oboInOwl:hasExactSynonym "response to X-ray radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010165" ; a owl:Class ; rdfs:label "response to X-ray" ; rdfs:subClassOf obo:GO_0010212 . obo:GO_0010212 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays." ; oboInOwl:hasExactSynonym "response to ionising radiation", "response to ionizing radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010212" ; a owl:Class ; rdfs:label "response to ionizing radiation" ; rdfs:subClassOf obo:GO_0009314 . obo:GO_0010256 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system." ; oboInOwl:hasExactSynonym "endomembrane organization", "endomembrane system organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010256" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "endomembrane system organization" ; rdfs:subClassOf obo:GO_0016043 . obo:GO_0010260 obo:IAO_0000115 "OBSOLETE. The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22732"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0010261" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010260" ; a owl:Class ; rdfs:comment "This term was obsoleted because there is no evidence that this process exists." ; rdfs:label "obsolete animal organ senescence" ; owl:deprecated true . obo:GO_0010269 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010269" ; a owl:Class ; rdfs:label "response to selenium ion" ; rdfs:subClassOf obo:GO_0010035 . obo:GO_0010288 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010288" ; a owl:Class ; rdfs:label "response to lead ion" ; rdfs:subClassOf obo:GO_0010038 . obo:GO_0010324 obo:IAO_0000115 "The infolding of a membrane." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-02T13:58:34Z" ; oboInOwl:hasAlternativeId "GO:1902534" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism membrane invagination" ; oboInOwl:id "GO:0010324" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "membrane invagination" ; rdfs:subClassOf obo:GO_0061024 . obo:GO_0010332 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to gamma ray", "response to gamma-ray photon" ; oboInOwl:id "GO:0010332" ; a owl:Class ; rdfs:label "response to gamma radiation" ; rdfs:subClassOf obo:GO_0010212 . obo:GO_0010389 obo:IAO_0000115 "Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." ; oboInOwl:hasExactSynonym "regulation of mitotic entry" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010389" ; a owl:Class ; rdfs:label "regulation of G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_1901990, obo:GO_1902749, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000086 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000086 ] ) ] . obo:GO_0010453 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010453" ; a owl:Class ; rdfs:label "regulation of cell fate commitment" ; rdfs:subClassOf obo:GO_0050793, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045165 ] ) ] . obo:GO_0010454 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010454" ; a owl:Class ; rdfs:label "negative regulation of cell fate commitment" ; rdfs:subClassOf obo:GO_0010453, obo:GO_0045596, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045165 ] ) ] . obo:GO_0010455 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010455" ; a owl:Class ; rdfs:label "positive regulation of cell fate commitment" ; rdfs:subClassOf obo:GO_0010453, obo:GO_0045597, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045165 ] ) ] . obo:GO_0010467 obo:IAO_0000115 "The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/25419"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Gene_expression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010467" ; oboInOwl:inSubset go:goslim_flybase_ribbon ; a owl:Class ; rdfs:label "gene expression" ; rdfs:subClassOf obo:GO_0009059 . obo:GO_0010468 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Regulation_of_gene_expression" ; oboInOwl:hasNarrowSynonym "regulation of protein expression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "gene regulation", "regulation of gene product expression" ; oboInOwl:id "GO:0010468" ; a owl:Class ; rdfs:comment "This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation." ; rdfs:label "regulation of gene expression" ; rdfs:subClassOf obo:GO_0010556, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010467 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010467 ] ) ] . obo:GO_0010470 obo:IAO_0000115 "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010470" ; a owl:Class ; rdfs:label "regulation of gastrulation" ; rdfs:subClassOf obo:GO_0022603, obo:GO_0045995, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007369 ] ) ] . obo:GO_0010506 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010506" ; a owl:Class ; rdfs:label "regulation of autophagy" ; rdfs:subClassOf obo:GO_0031329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006914 ] ) ] . obo:GO_0010507 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010507" ; a owl:Class ; rdfs:label "negative regulation of autophagy" ; rdfs:subClassOf obo:GO_0010506, obo:GO_0031330, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006914 ] ) ] . obo:GO_0010508 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010508" ; a owl:Class ; rdfs:label "positive regulation of autophagy" ; rdfs:subClassOf obo:GO_0010506, obo:GO_0031331, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006914 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006914 ] ) ] . obo:GO_0010549 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of membrane disassembly." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010549" ; a owl:Class ; rdfs:label "regulation of membrane disassembly" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030397 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030397 ] ) ] . obo:GO_0010556 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010556" ; a owl:Class ; rdfs:label "regulation of macromolecule biosynthetic process" ; rdfs:subClassOf obo:GO_0031326, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009059 ] ) ] . obo:GO_0010557 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010557" ; a owl:Class ; rdfs:label "positive regulation of macromolecule biosynthetic process" ; rdfs:subClassOf obo:GO_0010556, obo:GO_0010604, obo:GO_0031328, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009059 ] ) ] . obo:GO_0010558 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010558" ; a owl:Class ; rdfs:label "negative regulation of macromolecule biosynthetic process" ; rdfs:subClassOf obo:GO_0010556, obo:GO_0010605, obo:GO_0031327, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009059 ] ) ] . obo:GO_0010562 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010562" ; a owl:Class ; rdfs:label "positive regulation of phosphorus metabolic process" ; rdfs:subClassOf obo:GO_0031325, obo:GO_0051174, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006793 ] ) ] . obo:GO_0010563 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010563" ; a owl:Class ; rdfs:label "negative regulation of phosphorus metabolic process" ; rdfs:subClassOf obo:GO_0031324, obo:GO_0051174, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006793 ] ) ] . obo:GO_0010564 obo:IAO_0000115 "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010564" ; a owl:Class ; rdfs:label "regulation of cell cycle process" ; rdfs:subClassOf obo:GO_0051726, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022402 ] ) ] . obo:GO_0010571 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." ; oboInOwl:hasExactSynonym "positive regulation of DNA replication involved in S phase", "positive regulation of DNA replication involved in S-phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of DNA replication during S phase" ; oboInOwl:id "GO:0010571" ; a owl:Class ; rdfs:label "positive regulation of nuclear cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0033262, obo:GO_0090068, obo:GO_2000105, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0033260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0033260 ] ) ] . obo:GO_0010604 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010604" ; a owl:Class ; rdfs:label "positive regulation of macromolecule metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043170 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043170 ] ) ] . obo:GO_0010605 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010605" ; a owl:Class ; rdfs:label "negative regulation of macromolecule metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043170 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043170 ] ) ] . obo:GO_0010608 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript." ; oboInOwl:hasExactSynonym "posttranscriptional regulation of gene expression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010608" ; a owl:Class ; rdfs:label "post-transcriptional regulation of gene expression" ; rdfs:subClassOf obo:GO_0010468 . obo:GO_0010623 obo:IAO_0000115 "The activation of endogenous cellular processes that result in the death of a cell as part of its development." ; oboInOwl:hasBroadSynonym "developmental programmed cell death", "programmed cell death involved in development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010623" ; a owl:Class ; rdfs:comment "This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure." ; rdfs:label "programmed cell death involved in cell development" ; rdfs:subClassOf obo:GO_0012501, obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0012501 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ] ) ] . obo:GO_0010628 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010628" ; a owl:Class ; rdfs:label "positive regulation of gene expression" ; rdfs:subClassOf obo:GO_0010468, obo:GO_0010557, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010467 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010467 ] ) ] . obo:GO_0010629 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "gene silencing" ; oboInOwl:id "GO:0010629" ; a owl:Class ; rdfs:comment "This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation." ; rdfs:label "negative regulation of gene expression" ; rdfs:subClassOf obo:GO_0010468, obo:GO_0010558, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010467 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010467 ] ) ] . obo:GO_0010638 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ; oboInOwl:hasExactSynonym "positive regulation of organelle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of organelle organization and biogenesis" ; oboInOwl:id "GO:0010638" ; a owl:Class ; rdfs:label "positive regulation of organelle organization" ; rdfs:subClassOf obo:GO_0033043, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006996 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006996 ] ) ] . obo:GO_0010639 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ; oboInOwl:hasExactSynonym "negative regulation of organelle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of organelle organization and biogenesis" ; oboInOwl:id "GO:0010639" ; a owl:Class ; rdfs:label "negative regulation of organelle organization" ; rdfs:subClassOf obo:GO_0033043, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006996 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006996 ] ) ] . obo:GO_0010646 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010646" ; a owl:Class ; rdfs:label "regulation of cell communication" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007154 ] ) ] . obo:GO_0010647 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010647" ; a owl:Class ; rdfs:label "positive regulation of cell communication" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007154 ] ) ] . obo:GO_0010648 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010648" ; a owl:Class ; rdfs:label "negative regulation of cell communication" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007154 ] ) ] . obo:GO_0010720 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010720" ; a owl:Class ; rdfs:label "positive regulation of cell development" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048468 ] ) ] . obo:GO_0010721 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010721" ; a owl:Class ; rdfs:label "negative regulation of cell development" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048468 ] ) ] . obo:GO_0010770 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24299"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010770" ; a owl:Class ; rdfs:label "positive regulation of cell morphogenesis" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0022604, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000902 ] ) ] . obo:GO_0010771 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24299"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010771" ; a owl:Class ; rdfs:label "negative regulation of cell morphogenesis" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0022604, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000902 ] ) ] . obo:GO_0010793 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010793" ; a owl:Class ; rdfs:label "regulation of mRNA export from nucleus" ; rdfs:subClassOf obo:GO_0046831, obo:GO_2000197, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006406 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006406 ] ) ] . obo:GO_0010817 obo:IAO_0000115 "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010817" ; a owl:Class ; rdfs:label "regulation of hormone levels" ; rdfs:subClassOf obo:GO_0065008 . obo:GO_0010821 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." ; oboInOwl:hasExactSynonym "regulation of mitochondrion organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010821" ; a owl:Class ; rdfs:label "regulation of mitochondrion organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007005 ] ) ] . obo:GO_0010822 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." ; oboInOwl:hasExactSynonym "positive regulation of mitochondrion organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010822" ; a owl:Class ; rdfs:label "positive regulation of mitochondrion organization" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0010821, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007005 ] ) ] . obo:GO_0010823 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion." ; oboInOwl:hasExactSynonym "negative regulation of mitochondrion organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010823" ; a owl:Class ; rdfs:label "negative regulation of mitochondrion organization" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0010821, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007005 ] ) ] . obo:GO_0010833 obo:IAO_0000115 "Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010833" ; a owl:Class ; rdfs:label "telomere maintenance via telomere lengthening" ; rdfs:subClassOf obo:GO_0000723 . obo:GO_0010892 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010892" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial translation in response to stress" ; rdfs:subClassOf obo:GO_0032056, obo:GO_0070131 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032543 ] ) ] . obo:GO_0010927 obo:IAO_0000115 "The cellular component assembly that is part of the initial shaping of the component during its developmental progression." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010927" ; a owl:Class ; rdfs:label "cellular component assembly involved in morphogenesis" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0048646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032989 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022607 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ) ] . obo:GO_0010937 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010937" ; a owl:Class ; rdfs:label "regulation of cytoplasmic microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031114, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010938 ] ) ] . obo:GO_0010938 obo:IAO_0000115 "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010938" ; a owl:Class ; rdfs:label "cytoplasmic microtubule depolymerization" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0007019, obo:GO_0031122, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007019 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0010948 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-04-27T09:53:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010948" ; a owl:Class ; rdfs:label "negative regulation of cell cycle process" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0045786, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022402 ] ) ] . obo:GO_0010965 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-20T11:39:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010965" ; a owl:Class ; rdfs:label "regulation of mitotic sister chromatid separation" ; rdfs:subClassOf obo:GO_1905818, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051306 ] ) ] . obo:GO_0010968 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-20T11:51:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010968" ; a owl:Class ; rdfs:label "regulation of microtubule nucleation" ; rdfs:subClassOf obo:GO_0031113, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007020 ] ) ] . obo:GO_0010970 obo:IAO_0000115 "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-05-27T10:56:08Z" ; oboInOwl:hasBroadSynonym "microtubule-based transport" ; oboInOwl:hasExactSynonym "establishment of localization by movement along microtubule", "movement along microtubule" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010970" ; a owl:Class ; rdfs:label "transport along microtubule" ; rdfs:subClassOf obo:GO_0007018, obo:GO_0030705, obo:GO_0099111 . obo:GO_0010971 obo:IAO_0000115 "Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:16:34Z" ; oboInOwl:hasAlternativeId "GO:0031662" ; oboInOwl:hasExactSynonym "positive regulation of mitotic entry" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle" ; oboInOwl:id "GO:0010971" ; a owl:Class ; rdfs:label "positive regulation of G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0010389, obo:GO_1901992, obo:GO_1902751, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000086 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000086 ] ) ] . obo:GO_0010972 obo:IAO_0000115 "Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:18:29Z" ; oboInOwl:hasExactSynonym "negative regulation of mitotic entry" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010972" ; a owl:Class ; rdfs:label "negative regulation of G2/M transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0010389, obo:GO_1901991, obo:GO_1902750, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000086 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000086 ] ) ] . obo:GO_0010975 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:44:45Z" ; oboInOwl:hasNarrowSynonym "regulation of neurite biosynthesis", "regulation of neurite development", "regulation of neurite formation", "regulation of neurite growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010975" ; a owl:Class ; rdfs:label "regulation of neuron projection development" ; rdfs:subClassOf obo:GO_0120035, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031175 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031175 ] ) ] . obo:GO_0010976 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:46:44Z" ; oboInOwl:hasNarrowSynonym "positive regulation of neurite biosynthesis", "positive regulation of neurite development", "positive regulation of neurite formation", "positive regulation of neurite growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0010976" ; a owl:Class ; rdfs:label "positive regulation of neuron projection development" ; rdfs:subClassOf obo:GO_0010975, obo:GO_0031346, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031175 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031175 ] ) ] . obo:GO_0010977 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-06-01T10:47:42Z" ; oboInOwl:hasNarrowSynonym "negative regulation of neurite biosynthesis", "negative regulation of neurite development", "negative regulation of neurite formation", "negative regulation of neurite growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "growth cone collapse" ; oboInOwl:id "GO:0010977" ; a owl:Class ; rdfs:label "negative regulation of neuron projection development" ; rdfs:subClassOf obo:GO_0010975, obo:GO_0031345, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031175 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031175 ] ) ] . obo:GO_0012501 obo:IAO_0000115 "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24835"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0016244" ; oboInOwl:hasBroadSynonym "regulated cell death" ; oboInOwl:hasDbXref "Wikipedia:Programmed_cell_death" ; oboInOwl:hasNarrowSynonym "caspase-independent cell death", "non-apoptotic programmed cell death", "nonapoptotic programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "PCD", "RCD", "caspase-independent apoptosis" ; oboInOwl:id "GO:0012501" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_plant, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children." ; rdfs:label "programmed cell death" ; rdfs:subClassOf obo:GO_0008219 . obo:GO_0012505 obo:IAO_0000115 "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles." ; oboInOwl:hasDbXref "Wikipedia:Endomembrane_system" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0012505" ; oboInOwl:inSubset go:goslim_candida, go:goslim_flybase_ribbon, go:goslim_yeast ; a owl:Class ; rdfs:label "endomembrane system" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005773 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005886 ] . obo:GO_0012506 obo:IAO_0000115 "The lipid bilayer surrounding any membrane-bounded vesicle in the cell." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1153182838" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0012506" ; a owl:Class ; rdfs:label "vesicle membrane" ; rdfs:subClassOf obo:GO_0031090, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031982 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031982 ] ) ] . obo:GO_0014041 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014041" ; a owl:Class ; rdfs:label "regulation of neuron maturation" ; rdfs:subClassOf obo:GO_0045664, obo:GO_1903429, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042551 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042551 ] ) ] . obo:GO_0014042 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of neuron maturation." ; oboInOwl:hasExactSynonym "up regulation of neuron maturation", "up-regulation of neuron maturation", "upregulation of neuron maturation" ; oboInOwl:hasNarrowSynonym "activation of neuron maturation", "stimulation of neuron maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014042" ; a owl:Class ; rdfs:label "positive regulation of neuron maturation" ; rdfs:subClassOf obo:GO_0014041, obo:GO_1903431, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042551 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042551 ] ) ] . obo:GO_0014043 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation." ; oboInOwl:hasExactSynonym "down regulation of neuron maturation", "down-regulation of neuron maturation", "downregulation of neuron maturation" ; oboInOwl:hasNarrowSynonym "inhibition of neuron maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0014043" ; a owl:Class ; rdfs:label "negative regulation of neuron maturation" ; rdfs:subClassOf obo:GO_0014041, obo:GO_1903430, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042551 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042551 ] ) ] . obo:GO_0014076 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to SSRI", "response to selective serotonin reuptake inhibitor" ; oboInOwl:id "GO:0014076" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to fluoxetine" ; rdfs:subClassOf obo:GO_0036276 . obo:GO_0015031 obo:IAO_0000115 "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasAlternativeId "GO:0015831" ; oboInOwl:hasNarrowSynonym "enzyme transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0015031" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "protein transport" ; rdfs:subClassOf obo:GO_0045184, obo:GO_0071702, obo:GO_0071705 . obo:GO_0015629 obo:IAO_0000115 "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0015629" ; a owl:Class ; rdfs:label "actin cytoskeleton" ; rdfs:subClassOf obo:GO_0005856 . obo:GO_0015630 obo:IAO_0000115 "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0015630" ; a owl:Class ; rdfs:label "microtubule cytoskeleton" ; rdfs:subClassOf obo:GO_0005856 . obo:GO_0015931 obo:IAO_0000115 "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:id "GO:0015931" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "nucleobase-containing compound transport" ; rdfs:subClassOf obo:GO_0071702, obo:GO_0071705 . obo:GO_0016020 obo:IAO_0000115 "A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it." ; oboInOwl:creation_date "2014-03-06T11:37:54Z" ; oboInOwl:hasAlternativeId "GO:0016021", "GO:0098589", "GO:0098805" ; oboInOwl:hasDbXref "Wikipedia:Biological_membrane", "Wikipedia:Transmembrane_protein" ; oboInOwl:hasNarrowSynonym "integral component of membrane", "integral to membrane", "membrane region", "region of membrane", "whole membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "transmembrane" ; oboInOwl:id "GO:0016020" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_metagenomics, go:goslim_pir, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:label "membrane" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0016043 obo:IAO_0000115 "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component." ; oboInOwl:hasAlternativeId "GO:0044235", "GO:0071842" ; oboInOwl:hasExactSynonym "cell organisation", "cellular component organisation at cellular level", "cellular component organisation in other organism", "cellular component organization at cellular level", "cellular component organization in other organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell organization and biogenesis" ; oboInOwl:id "GO:0016043" ; oboInOwl:inSubset go:goslim_agr, go:goslim_mouse, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "cellular component organization" ; rdfs:subClassOf obo:GO_0071840 . obo:GO_0016049 obo:IAO_0000115 "The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present." ; oboInOwl:hasAlternativeId "GO:0048591" ; oboInOwl:hasExactSynonym "cellular growth", "growth of cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell expansion", "metabolic process resulting in cell growth", "metabolism resulting in cell growth", "non-developmental cell growth", "non-developmental growth of a unicellular organism" ; oboInOwl:id "GO:0016049" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_drosophila, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "cell growth" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0040007 . obo:GO_0016050 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle." ; oboInOwl:hasExactSynonym "vesicle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "vesicle organization and biogenesis" ; oboInOwl:id "GO:0016050" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "vesicle organization" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0016070 obo:IAO_0000115 "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; oboInOwl:hasExactSynonym "RNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016070" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_metagenomics, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "RNA metabolic process" ; rdfs:subClassOf obo:GO_0090304 . obo:GO_0016071 obo:IAO_0000115 "The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." ; oboInOwl:hasExactSynonym "mRNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016071" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "mRNA metabolic process" ; rdfs:subClassOf obo:GO_0016070 . obo:GO_0016079 obo:IAO_0000115 "Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016079" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle exocytosis" ; rdfs:subClassOf obo:GO_0045055, obo:GO_0051649, obo:GO_0099003, obo:GO_0099643, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007269 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099504 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045055 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0016192 obo:IAO_0000115 "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25421"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006899" ; oboInOwl:hasExactSynonym "vesicle transport", "vesicular transport" ; oboInOwl:hasNarrowSynonym "nonselective vesicle transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein sorting along secretory pathway", "vesicle trafficking" ; oboInOwl:id "GO:0016192" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe ; a owl:Class ; rdfs:label "vesicle-mediated transport" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0009987 . obo:GO_0016203 obo:IAO_0000115 "The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016203" ; a owl:Class ; rdfs:label "muscle attachment" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060538 ] . obo:GO_0016236 obo:IAO_0000115 "The autophagic process that proceeds via the formation of an autophagosome." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/26115"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0034262" ; oboInOwl:hasBroadSynonym "autophagy" ; oboInOwl:hasNarrowSynonym "selective autophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016236" ; a owl:Class ; rdfs:label "macroautophagy" ; rdfs:subClassOf obo:GO_0006914 . obo:GO_0016239 obo:IAO_0000115 "Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation." ; oboInOwl:hasExactSynonym "positive regulation of starvation-induced autophagy", "up regulation of macroautophagy", "up-regulation of macroautophagy", "upregulation of macroautophagy" ; oboInOwl:hasNarrowSynonym "activation of macroautophagy", "stimulation of macroautophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016239" ; a owl:Class ; rdfs:label "positive regulation of macroautophagy" ; rdfs:subClassOf obo:GO_0010508, obo:GO_0016241, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016236 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016236 ] ) ] . obo:GO_0016241 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of macroautophagy." ; oboInOwl:hasExactSynonym "regulation of starvation-induced autophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016241" ; a owl:Class ; rdfs:label "regulation of macroautophagy" ; rdfs:subClassOf obo:GO_0010506, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016236 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016236 ] ) ] . obo:GO_0016242 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy." ; oboInOwl:hasExactSynonym "down regulation of macroautophagy", "down-regulation of macroautophagy", "downregulation of macroautophagy", "negative regulation of starvation-induced autophagy" ; oboInOwl:hasNarrowSynonym "inhibition of macroautophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016242" ; a owl:Class ; rdfs:label "negative regulation of macroautophagy" ; rdfs:subClassOf obo:GO_0010507, obo:GO_0016241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016236 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016236 ] ) ] . obo:GO_0016246 obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:GO_0035194 ; a owl:Class ; owl:deprecated true . obo:GO_0016301 obo:IAO_0000115 "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule." ; oboInOwl:hasDbXref "Reactome:R-HSA-6788855", "Reactome:R-HSA-6788867" ; oboInOwl:hasExactSynonym "phosphokinase activity" ; oboInOwl:id "GO:0016301" ; a owl:Class ; rdfs:comment "Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term." ; rdfs:label "kinase activity" ; rdfs:subClassOf obo:GO_0003674, [ a owl:Restriction ; owl:hasSelf true ; owl:onProperty obo:RO_0002481 ] . obo:GO_0016310 obo:IAO_0000115 "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide." ; oboInOwl:hasDbXref "Wikipedia:Phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016310" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_metagenomics ; a owl:Class ; rdfs:label "phosphorylation" ; rdfs:subClassOf obo:GO_0006796 . obo:GO_0016321 obo:IAO_0000115 "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016321" ; a owl:Class ; rdfs:label "female meiosis chromosome segregation" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0045132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098813 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ) ] . obo:GO_0016358 obo:IAO_0000115 "The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016358" ; a owl:Class ; rdfs:label "dendrite development" ; rdfs:subClassOf obo:GO_0031175, obo:GO_0048856 . obo:GO_0016459 obo:IAO_0000115 "A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0016459" ; a owl:Class ; rdfs:label "myosin complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0015629 ] . obo:GO_0016460 obo:IAO_0000115 "A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "conventional myosin" ; oboInOwl:id "GO:0016460" ; a owl:Class ; rdfs:label "myosin II complex" ; rdfs:subClassOf obo:GO_0016459 . obo:GO_0016477 obo:IAO_0000115 "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24787"^^xsd:anyURI ; obo:RO_0002161 obo:NCBITaxon_4890 ; oboInOwl:hasDbXref "Wikipedia:Cell_migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016477" ; a owl:Class ; rdfs:label "cell migration" ; rdfs:subClassOf obo:GO_0048870 . obo:GO_0016482 obo:IAO_0000115 "The directed movement of substances or organelles within the cytosol." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0016482" ; a owl:Class ; rdfs:label "cytosolic transport" ; rdfs:subClassOf obo:GO_0046907, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005829 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005829 ] ) ] . obo:GO_0016740 obo:IAO_0000115 "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." ; oboInOwl:hasDbXref "EC:2.-.-.-", "Reactome:R-HSA-1483089", "Reactome:R-HSA-1483186", "Reactome:R-HSA-5668414", "Reactome:R-HSA-8868783" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016740" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "transferase activity" ; rdfs:subClassOf obo:GO_0003824 . obo:GO_0016757 obo:IAO_0000115 "Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor)." ; oboInOwl:hasAlternativeId "GO:0016932" ; oboInOwl:hasDbXref "EC:2.4.-.-", "Reactome:R-HSA-5173005", "Reactome:R-HSA-6785565" ; oboInOwl:hasExactSynonym "transferase activity, transferring glycosyl groups", "transglycosidase activity", "transglycosylase activity" ; oboInOwl:hasNarrowSynonym "transferase activity, transferring other glycosyl groups" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016757" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_yeast ; a owl:Class ; rdfs:label "glycosyltransferase activity" ; rdfs:subClassOf obo:GO_0016740 . obo:GO_0016787 obo:IAO_0000115 "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc." ; oboInOwl:hasDbXref "EC:3.-.-.-", "Reactome:R-HSA-1236938", "Reactome:R-HSA-2029475", "Reactome:R-HSA-5694583", "Reactome:R-HSA-5695964", "Reactome:R-HSA-6786190", "Reactome:R-HSA-6788295", "Reactome:R-HSA-8938314", "Reactome:R-HSA-8952137" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016787" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_mouse, go:goslim_pir, go:goslim_plant, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:label "hydrolase activity" ; rdfs:subClassOf obo:GO_0003824 . obo:GO_0016788 obo:IAO_0000115 "Catalysis of the hydrolysis of any ester bond." ; oboInOwl:hasDbXref "EC:3.1.-.-", "Reactome:R-HSA-162729", "Reactome:R-HSA-9023617", "Reactome:R-HSA-9023619", "Reactome:R-HSA-9749609" ; oboInOwl:hasExactSynonym "esterase activity" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0016788" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "hydrolase activity, acting on ester bonds" ; rdfs:subClassOf obo:GO_0016787 . obo:GO_0017148 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ; oboInOwl:hasAlternativeId "GO:0016478" ; oboInOwl:hasExactSynonym "down regulation of protein biosynthetic process", "down-regulation of protein biosynthetic process", "downregulation of protein biosynthetic process", "negative regulation of protein anabolism", "negative regulation of protein biosynthesis", "negative regulation of protein biosynthetic process", "negative regulation of protein formation", "negative regulation of protein synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of protein biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein biosynthesis inhibitor activity", "protein biosynthetic process inhibitor activity" ; oboInOwl:id "GO:0017148" ; a owl:Class ; rdfs:label "negative regulation of translation" ; rdfs:subClassOf obo:GO_0006417, obo:GO_0010629, obo:GO_0034249, obo:GO_0051248, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0017157 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of exocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0017157" ; a owl:Class ; rdfs:label "regulation of exocytosis" ; rdfs:subClassOf obo:GO_0060627, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006887 ] ) ] . obo:GO_0018130 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." ; oboInOwl:hasExactSynonym "heterocycle anabolism", "heterocycle biosynthesis", "heterocycle formation", "heterocycle synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018130" ; a owl:Class ; rdfs:label "heterocycle biosynthetic process" ; rdfs:subClassOf obo:GO_0044249, obo:GO_0046483 . obo:GO_0018958 obo:IAO_0000115 "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ; oboInOwl:hasDbXref "UM-BBD_pathwayID:phe" ; oboInOwl:hasExactSynonym "carbolic acid metabolic process", "carbolic acid metabolism", "hydroxybenzene metabolic process", "hydroxybenzene metabolism", "phenol-containing compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018958" ; a owl:Class ; rdfs:comment "Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds." ; rdfs:label "phenol-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_1901360, obo:GO_1901615 . obo:GO_0018985 obo:IAO_0000115 "Synthesis and ordering of the envelope of pronuclei." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018985" ; a owl:Class ; rdfs:label "pronuclear envelope synthesis" ; rdfs:subClassOf obo:GO_0006998, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007338 ] . obo:GO_0018991 obo:IAO_0000115 "A reproductive behavior that results in the deposition of eggs (either fertilized or not) upon a surface or into a medium such as water." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24955"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0060403" ; oboInOwl:hasBroadSynonym "egg laying", "egg-laying" ; oboInOwl:hasDbXref "Wikipedia:Oviposition" ; oboInOwl:hasExactSynonym "oviposition" ; oboInOwl:hasNarrowSynonym "post-mating oviposition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018991" ; a owl:Class ; rdfs:label "egg-laying behavior" ; rdfs:subClassOf obo:GO_0019098 . obo:GO_0018992 obo:IAO_0000115 "The determination of sex and sexual phenotype in an organism's germ line." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018992" ; a owl:Class ; rdfs:label "germ-line sex determination" ; rdfs:subClassOf obo:GO_0007530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0018996 obo:IAO_0000115 "The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans." ; oboInOwl:hasExactSynonym "collagen and cuticulin-based cuticle molting cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0018996" ; a owl:Class ; rdfs:label "molting cycle, collagen and cuticulin-based cuticle" ; rdfs:subClassOf obo:GO_0042303 . obo:GO_0019093 obo:IAO_0000115 "Any process in which mitochondrial RNA is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "establishment and maintenance of mitochondrial RNA localization", "mitochondrial RNA localisation", "mtRNA localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019093" ; a owl:Class ; rdfs:label "mitochondrial RNA localization" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0006403, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006403 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0019098 obo:IAO_0000115 "The specific behavior of an organism that is associated with reproduction." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23491"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T16:01:37Z" ; oboInOwl:hasAlternativeId "GO:0033057", "GO:0044704", "GO:0044705" ; oboInOwl:hasExactSynonym "reproductive behavior in a multicellular organism", "reproductive behaviour" ; oboInOwl:hasNarrowSynonym "multi-organism reproductive behavior", "multicellular organism reproductive behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism reproductive behavior" ; oboInOwl:id "GO:0019098" ; a owl:Class ; rdfs:label "reproductive behavior" ; rdfs:subClassOf obo:GO_0007610, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007610 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] ) ] . obo:GO_0019216 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids." ; oboInOwl:hasExactSynonym "regulation of lipid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019216" ; a owl:Class ; rdfs:label "regulation of lipid metabolic process" ; rdfs:subClassOf obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006629 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006629 ] ) ] . obo:GO_0019219 obo:IAO_0000115 "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:id "GO:0019219" ; a owl:Class ; rdfs:label "regulation of nucleobase-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0031323, obo:GO_0051171, obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006139 ] ) ] . obo:GO_0019220 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ; oboInOwl:hasExactSynonym "regulation of phosphate metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019220" ; a owl:Class ; rdfs:label "regulation of phosphate metabolic process" ; rdfs:subClassOf obo:GO_0051174, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006796 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006796 ] ) ] . obo:GO_0019222 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism." ; oboInOwl:hasAlternativeId "GO:0044246" ; oboInOwl:hasExactSynonym "regulation of metabolism" ; oboInOwl:hasNarrowSynonym "regulation of multicellular organismal metabolic process", "regulation of organismal metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019222" ; oboInOwl:inSubset go:goslim_metagenomics ; a owl:Class ; rdfs:label "regulation of metabolic process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008152 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008152 ] ) ] . obo:GO_0019226 a owl:Class . obo:GO_0019336 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ; oboInOwl:hasDbXref "MetaCyc:PHENOLDEG-PWY" ; oboInOwl:hasExactSynonym "phenol-containing compound breakdown", "phenol-containing compound catabolism", "phenol-containing compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019336" ; a owl:Class ; rdfs:label "phenol-containing compound catabolic process" ; rdfs:subClassOf obo:GO_0018958, obo:GO_0019439, obo:GO_1901361, obo:GO_1901616 . obo:GO_0019438 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring." ; oboInOwl:hasExactSynonym "aromatic compound anabolism", "aromatic compound biosynthesis", "aromatic compound formation", "aromatic compound synthesis" ; oboInOwl:hasNarrowSynonym "aromatic hydrocarbon biosynthesis", "aromatic hydrocarbon biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019438" ; a owl:Class ; rdfs:label "aromatic compound biosynthetic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_0044249 . obo:GO_0019439 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring." ; oboInOwl:hasExactSynonym "aromatic compound breakdown", "aromatic compound catabolism", "aromatic compound degradation" ; oboInOwl:hasNarrowSynonym "aromatic hydrocarbon catabolic process", "aromatic hydrocarbon catabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019439" ; a owl:Class ; rdfs:label "aromatic compound catabolic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_0044248 . obo:GO_0019538 obo:IAO_0000115 "The chemical reactions and pathways involving a protein. Includes protein modification." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006411", "GO:0044267", "GO:0044268" ; oboInOwl:hasDbXref "Wikipedia:Protein_metabolism" ; oboInOwl:hasExactSynonym "cellular protein metabolic process", "cellular protein metabolism", "protein metabolic process and modification", "protein metabolism", "protein metabolism and modification" ; oboInOwl:hasNarrowSynonym "multicellular organismal protein metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019538" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "protein metabolic process" ; rdfs:subClassOf obo:GO_0043170, obo:GO_0044238, obo:GO_1901564 . obo:GO_0019614 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "catechol breakdown", "catechol catabolic process", "catechol catabolism", "catechol degradation" ; oboInOwl:id "GO:0019614" ; a owl:Class ; rdfs:label "catechol-containing compound catabolic process" ; rdfs:subClassOf obo:GO_0009712, obo:GO_0019336 . obo:GO_0019722 obo:IAO_0000115 "Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions." ; oboInOwl:hasDbXref "Wikipedia:Calcium_signaling" ; oboInOwl:hasExactSynonym "calcium ion signaling", "calcium signaling", "calcium signalling", "calcium-mediated signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019722" ; a owl:Class ; rdfs:label "calcium-mediated signaling" ; rdfs:subClassOf obo:GO_0019932 . obo:GO_0019725 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state at the level of the cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019725" ; oboInOwl:inSubset go:goslim_candida, go:goslim_plant ; a owl:Class ; rdfs:label "cellular homeostasis" ; rdfs:subClassOf obo:GO_0042592 . obo:GO_0019748 obo:IAO_0000115 "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients." ; oboInOwl:hasDbXref "Wikipedia:Secondary_metabolism" ; oboInOwl:hasExactSynonym "secondary metabolism", "secondary metabolite metabolic process", "secondary metabolite metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019748" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir, go:goslim_plant, go:goslim_pombe ; a owl:Class ; rdfs:label "secondary metabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0019932 obo:IAO_0000115 "Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell." ; oboInOwl:hasExactSynonym "second messenger mediated signaling", "second messenger mediated signalling", "second messenger-mediated signaling", "second messenger-mediated signalling", "second-messenger-mediated signal transduction", "second-messenger-mediated signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019932" ; a owl:Class ; rdfs:label "second-messenger-mediated signaling" ; rdfs:subClassOf obo:GO_0035556 . obo:GO_0019953 obo:IAO_0000115 "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22929"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Sexual_reproduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0019953" ; a owl:Class ; rdfs:comment "Note that gametes may come from two organisms or from a single organism in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. Note also that sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times." ; rdfs:label "sexual reproduction" ; rdfs:subClassOf obo:GO_0000003 . obo:GO_0021700 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0021700" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "developmental maturation" ; rdfs:subClassOf obo:GO_0032502 . obo:GO_0022008 obo:IAO_0000115 "Generation of cells within the nervous system." ; oboInOwl:hasDbXref "Wikipedia:Neurogenesis" ; oboInOwl:hasExactSynonym "nervous system cell generation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neural cell differentiation" ; oboInOwl:id "GO:0022008" ; a owl:Class ; rdfs:label "neurogenesis" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007399 ] . obo:GO_0022402 obo:IAO_0000115 "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022402" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "cell cycle process" ; rdfs:subClassOf obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0022403 obo:IAO_0000115 "One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022403" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "cell cycle phase" ; rdfs:subClassOf obo:GO_0044848 . obo:GO_0022404 obo:IAO_0000115 "A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022404" ; a owl:Class ; rdfs:label "molting cycle process" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042303 ] . obo:GO_0022407 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022407" ; a owl:Class ; rdfs:label "regulation of cell-cell adhesion" ; rdfs:subClassOf obo:GO_0030155, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0098609 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0022408 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell." ; oboInOwl:hasExactSynonym "down regulation of cell-cell adhesion", "down-regulation of cell-cell adhesion", "downregulation of cell-cell adhesion" ; oboInOwl:hasNarrowSynonym "inhibition of cell-cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022408" ; a owl:Class ; rdfs:label "negative regulation of cell-cell adhesion" ; rdfs:subClassOf obo:GO_0007162, obo:GO_0022407, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0098609 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0022409 obo:IAO_0000115 "Any process that activates or increases the rate or extent of cell adhesion to another cell." ; oboInOwl:hasExactSynonym "up regulation of cell-cell adhesion", "up-regulation of cell-cell adhesion", "upregulation of cell-cell adhesion" ; oboInOwl:hasNarrowSynonym "activation of cell-cell adhesion", "stimulation of cell-cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022409" ; a owl:Class ; rdfs:label "positive regulation of cell-cell adhesion" ; rdfs:subClassOf obo:GO_0022407, obo:GO_0045785, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0098609 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0022411 obo:IAO_0000115 "A cellular process that results in the breakdown of a cellular component." ; oboInOwl:hasAlternativeId "GO:0071845" ; oboInOwl:hasExactSynonym "cell structure disassembly", "cellular component disassembly at cellular level" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022411" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular component disassembly" ; rdfs:subClassOf obo:GO_0016043 ; owl:disjointWith obo:GO_0022607 . obo:GO_0022412 obo:IAO_0000115 "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism." ; oboInOwl:hasExactSynonym "reproductive cellular process in multicellular organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022412" ; a owl:Class ; rdfs:label "cellular process involved in reproduction in multicellular organism" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] ) ] . obo:GO_0022414 obo:IAO_0000115 "A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T15:56:06Z" ; oboInOwl:hasAlternativeId "GO:0044702" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism reproductive process" ; oboInOwl:id "GO:0022414" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "reproductive process" ; rdfs:subClassOf obo:GO_0008150, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000003 ] ; owl:disjointWith obo:GO_0044848 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000003 ] ) ] . obo:GO_0022600 obo:IAO_0000115 "A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022600" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "digestive system process" ; rdfs:subClassOf obo:GO_0003008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007586 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0003008 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007586 ] ) ] . obo:GO_0022603 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis." ; oboInOwl:hasExactSynonym "regulation of morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022603" ; a owl:Class ; rdfs:label "regulation of anatomical structure morphogenesis" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009653 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009653 ] ) ] . obo:GO_0022604 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell shape and cell size", "positive regulation of cell shape and cell size", "regulation of cell shape and cell size" ; oboInOwl:id "GO:0022604" ; a owl:Class ; rdfs:label "regulation of cell morphogenesis" ; rdfs:subClassOf obo:GO_0022603, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000902 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000902 ] ) ] . obo:GO_0022607 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a cellular component." ; oboInOwl:hasAlternativeId "GO:0071844" ; oboInOwl:hasExactSynonym "cell structure assembly", "cellular component assembly at cellular level" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022607" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "cellular component assembly" ; rdfs:subClassOf obo:GO_0016043, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044085 ] . obo:GO_0022611 obo:IAO_0000115 "A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated." ; oboInOwl:hasNarrowSynonym "multicellular organism dormancy process", "spore dormancy process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022611" ; a owl:Class ; rdfs:comment "In plants and animals, dormancy may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. In plants, dormancy may involve the formation of dormant buds, and may be preceded by the senescence of plant parts such as leaves in woody plants or most of the shoot system in herbaceous perennials. The exit from dormancy in vascular plants is marked by resumed growth of buds and/or growth of vascular cambium." ; rdfs:label "dormancy process" ; rdfs:subClassOf obo:GO_0032502 . obo:GO_0022613 obo:IAO_0000115 "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex." ; oboInOwl:hasExactSynonym "RNA-protein complex biogenesis", "ribonucleoprotein complex biogenesis and assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022613" ; a owl:Class ; rdfs:label "ribonucleoprotein complex biogenesis" ; rdfs:subClassOf obo:GO_0044085 . obo:GO_0022618 obo:IAO_0000115 "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex." ; oboInOwl:hasExactSynonym "RNA-protein complex assembly", "RNP complex assembly", "ribonucleoprotein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0022618" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "protein-RNA complex assembly" ; rdfs:subClassOf obo:GO_0065003, obo:GO_0071826, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0022613 ] . obo:GO_0023019 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of gene expression as a consequence of signal transmission" ; oboInOwl:id "GO:0023019" ; a owl:Class ; rdfs:label "signal transduction involved in regulation of gene expression" ; rdfs:subClassOf obo:GO_0007165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007165 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010468 ] ) ] . obo:GO_0023051 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a signaling process." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of signaling process", "regulation of signalling process" ; oboInOwl:id "GO:0023051" ; a owl:Class ; rdfs:label "regulation of signaling" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0023052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0023052 ] ) ] . obo:GO_0023052 obo:IAO_0000115 "The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasAlternativeId "GO:0023046", "GO:0044700" ; oboInOwl:hasExactSynonym "biological signaling", "signaling process", "signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "signalling process", "single organism signaling" ; oboInOwl:id "GO:0023052" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_mouse, go:goslim_pombe, go:goslim_yeast, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change." ; rdfs:label "signaling" ; rdfs:subClassOf obo:GO_0050789 ; owl:disjointWith obo:GO_0044848 . obo:GO_0023056 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasExactSynonym "positive regulation of signalling process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of signaling process" ; oboInOwl:id "GO:0023056" ; a owl:Class ; rdfs:label "positive regulation of signaling" ; rdfs:subClassOf obo:GO_0023051, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0023052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0023052 ] ) ] . obo:GO_0023057 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of signaling process", "negative regulation of signalling process" ; oboInOwl:id "GO:0023057" ; a owl:Class ; rdfs:label "negative regulation of signaling" ; rdfs:subClassOf obo:GO_0023051, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0023052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0023052 ] ) ] . obo:GO_0023061 obo:IAO_0000115 "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source." ; oboInOwl:creation_date "2010-02-16T09:30:50Z" ; oboInOwl:hasExactSynonym "signal secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0023061" ; a owl:Class ; rdfs:label "signal release" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0032940, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007267 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032940 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007267 ] ) ] . obo:GO_0030003 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "cellular cation homeostasis" ; oboInOwl:hasExactSynonym "cellular monoatomic cation homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030003" ; a owl:Class ; rdfs:label "intracellular monoatomic cation homeostasis" ; rdfs:subClassOf obo:GO_0006873, obo:GO_0055080 . obo:GO_0030010 obo:IAO_0000115 "The specification and formation of anisotropic intracellular organization or cell growth patterns." ; oboInOwl:hasAlternativeId "GO:0000283", "GO:0030468" ; oboInOwl:hasExactSynonym "cell polarization" ; oboInOwl:hasNarrowSynonym "bud site selection/establishment of cell polarity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030010" ; a owl:Class ; rdfs:label "establishment of cell polarity" ; rdfs:subClassOf obo:GO_0007163 . obo:GO_0030016 obo:IAO_0000115 "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism." ; oboInOwl:hasDbXref "Wikipedia:Myofibril" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030016" ; a owl:Class ; rdfs:label "myofibril" ; rdfs:subClassOf obo:GO_0043292 . obo:GO_0030017 obo:IAO_0000115 "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs." ; oboInOwl:hasDbXref "Wikipedia:Sarcomere" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030017" ; a owl:Class ; rdfs:label "sarcomere" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030016 ] . obo:GO_0030029 obo:IAO_0000115 "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microfilament-based process" ; oboInOwl:id "GO:0030029" ; a owl:Class ; rdfs:label "actin filament-based process" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0030030 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/26279"^^xsd:anyURI ; oboInOwl:hasExactSynonym "cell projection organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell projection organization and biogenesis", "cell surface structure organization and biogenesis" ; oboInOwl:id "GO:0030030" ; oboInOwl:inSubset go:prokaryote_subset ; a owl:Class ; rdfs:label "cell projection organization" ; rdfs:subClassOf obo:GO_0016043 . obo:GO_0030036 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23114"^^xsd:anyURI ; oboInOwl:hasExactSynonym "actin cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "actin cytoskeleton organization and biogenesis", "actin modulating activity" ; oboInOwl:id "GO:0030036" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "actin cytoskeleton organization" ; rdfs:subClassOf obo:GO_0007010, obo:GO_0030029 . obo:GO_0030037 obo:IAO_0000115 "OBSOLETE. The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14087"^^xsd:anyURI ; obo:IAO_0100001 "GO:0007015" ; oboInOwl:hasExactSynonym "actin filament reorganisation involved in cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "actin filament reorganization during cell cycle" ; oboInOwl:id "GO:0030037" ; a owl:Class ; rdfs:comment "This term was obsoleted because it is a pre-composed term." ; rdfs:label "obsolete actin filament reorganization involved in cell cycle" ; owl:deprecated true . obo:GO_0030054 obo:IAO_0000115 "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "Wikipedia:Cell_junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030054" ; oboInOwl:inSubset go:goslim_agr, go:goslim_drosophila, go:goslim_flybase_ribbon ; a owl:Class ; rdfs:label "cell junction" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0030071 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030071" ; a owl:Class ; rdfs:label "regulation of mitotic metaphase/anaphase transition" ; rdfs:subClassOf obo:GO_1901990, obo:GO_1902099, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007091 ] ) ] . obo:GO_0030100 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of endocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030100" ; a owl:Class ; rdfs:label "regulation of endocytosis" ; rdfs:subClassOf obo:GO_0051128, obo:GO_0060627, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006897 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006897 ] ) ] . obo:GO_0030104 obo:IAO_0000115 "OBSOLETE. Any process involved in the maintenance of an internal steady state of water within an organism or cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24726"^^xsd:anyURI ; oboInOwl:consider "GO:0003091", "GO:0009992", "GO:0050891" ; oboInOwl:hasAlternativeId "GO:0018987" ; oboInOwl:hasDbXref "Wikipedia:Osmoregulation" ; oboInOwl:hasExactSynonym "regulation of osmotic pressure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "osmoregulation" ; oboInOwl:id "GO:0030104" ; a owl:Class ; rdfs:comment "The reason for obsoletion is that this term does not specify whether the process is intracellular or organism-level." ; rdfs:label "obsolete water homeostasis" ; owl:deprecated true . obo:GO_0030133 obo:IAO_0000115 "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell." ; oboInOwl:hasDbXref "NIF_Subcellular:sao885490876" ; oboInOwl:hasExactSynonym "constitutive secretory pathway transport vesicle" ; oboInOwl:hasNarrowSynonym "Golgi to vacuole transport vesicle", "Golgi-vacuole transport vesicle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "secretory vesicle" ; oboInOwl:id "GO:0030133" ; a owl:Class ; rdfs:comment "Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'." ; rdfs:label "transport vesicle" ; rdfs:subClassOf obo:GO_0031410, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0012505 ] . obo:GO_0030154 obo:IAO_0000115 "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Cellular_differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030154" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_mouse, go:goslim_plant ; a owl:Class ; rdfs:label "cell differentiation" ; rdfs:subClassOf obo:GO_0048869 . obo:GO_0030155 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell adhesion receptor regulator activity" ; oboInOwl:id "GO:0030155" ; a owl:Class ; rdfs:label "regulation of cell adhesion" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007155 ] ) ] . obo:GO_0030163 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0044254", "GO:0044257" ; oboInOwl:hasDbXref "Wikipedia:Protein_catabolism" ; oboInOwl:hasExactSynonym "cellular protein breakdown", "cellular protein catabolic process", "cellular protein catabolism", "cellular protein degradation", "protein breakdown", "protein catabolism", "protein degradation" ; oboInOwl:hasNarrowSynonym "multicellular organismal protein catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pheromone catabolic process", "pheromone catabolism" ; oboInOwl:id "GO:0030163" ; oboInOwl:inSubset go:goslim_candida, go:goslim_drosophila, go:goslim_generic, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:comment "This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children." ; rdfs:label "protein catabolic process" ; rdfs:subClassOf obo:GO_0009057, obo:GO_0019538, obo:GO_1901565 . obo:GO_0030174 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase." ; oboInOwl:hasBroadSynonym "regulation of DNA replication initiation" ; oboInOwl:hasExactSynonym "DNA replication licencing", "DNA replication licensing", "regulation of DNA-dependent DNA replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030174" ; a owl:Class ; rdfs:label "regulation of DNA-templated DNA replication initiation" ; rdfs:subClassOf obo:GO_0090329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006270 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006270 ] ) ] . obo:GO_0030182 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a neuron." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030182" ; a owl:Class ; rdfs:label "neuron differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048699 ] . obo:GO_0030261 obo:IAO_0000115 "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." ; oboInOwl:hasAlternativeId "GO:0000068" ; oboInOwl:hasBroadSynonym "DNA condensation" ; oboInOwl:hasExactSynonym "eukaryotic chromosome condensation", "nuclear chromosome condensation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030261" ; a owl:Class ; rdfs:label "chromosome condensation" ; rdfs:subClassOf obo:GO_0051276 . obo:GO_0030307 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, extent or direction of cell growth." ; oboInOwl:hasExactSynonym "up regulation of cell growth", "up-regulation of cell growth", "upregulation of cell growth" ; oboInOwl:hasNarrowSynonym "activation of cell growth", "stimulation of cell growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030307" ; a owl:Class ; rdfs:label "positive regulation of cell growth" ; rdfs:subClassOf obo:GO_0001558, obo:GO_0045927, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016049 ] ) ] . obo:GO_0030308 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth." ; oboInOwl:hasExactSynonym "down regulation of cell growth", "down-regulation of cell growth", "downregulation of cell growth" ; oboInOwl:hasNarrowSynonym "inhibition of cell growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030308" ; a owl:Class ; rdfs:label "negative regulation of cell growth" ; rdfs:subClassOf obo:GO_0001558, obo:GO_0045926, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016049 ] ) ] . obo:GO_0030312 obo:IAO_0000115 "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030312" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:comment "The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'." ; rdfs:label "external encapsulating structure" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071944 ] . obo:GO_0030334 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell migration." ; obo:RO_0002161 obo:NCBITaxon_4890 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030334" ; a owl:Class ; rdfs:label "regulation of cell migration" ; rdfs:subClassOf obo:GO_2000145, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016477 ] ) ] . obo:GO_0030335 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell migration." ; oboInOwl:hasExactSynonym "up regulation of cell migration", "up-regulation of cell migration", "upregulation of cell migration" ; oboInOwl:hasNarrowSynonym "activation of cell migration", "stimulation of cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030335" ; a owl:Class ; rdfs:label "positive regulation of cell migration" ; rdfs:subClassOf obo:GO_0030334, obo:GO_2000147, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016477 ] ) ] . obo:GO_0030336 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration." ; oboInOwl:hasExactSynonym "down regulation of cell migration", "down-regulation of cell migration", "downregulation of cell migration" ; oboInOwl:hasNarrowSynonym "inhibition of cell migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030336" ; a owl:Class ; rdfs:label "negative regulation of cell migration" ; rdfs:subClassOf obo:GO_0030334, obo:GO_2000146, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016477 ] ) ] . obo:GO_0030397 obo:IAO_0000115 "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy." ; oboInOwl:hasExactSynonym "membrane breakdown", "membrane catabolism", "membrane degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030397" ; a owl:Class ; rdfs:label "membrane disassembly" ; rdfs:subClassOf obo:GO_0022411, obo:GO_0061024 . obo:GO_0030421 obo:IAO_0000115 "The expulsion of feces from the rectum." ; oboInOwl:hasDbXref "Wikipedia:Defecation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030421" ; a owl:Class ; rdfs:label "defecation" ; rdfs:subClassOf obo:GO_0007588, obo:GO_0022600 . obo:GO_0030424 obo:IAO_0000115 "The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1770195789", "Wikipedia:Axon" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030424" ; a owl:Class ; rdfs:label "axon" ; rdfs:subClassOf obo:GO_0043005 . obo:GO_0030425 obo:IAO_0000115 "A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1211023249", "Wikipedia:Dendrite" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030425" ; a owl:Class ; rdfs:label "dendrite" ; rdfs:subClassOf obo:GO_0043005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0097447 ] . obo:GO_0030516 obo:IAO_0000115 "Any process that modulates the rate, direction or extent of axon extension." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030516" ; a owl:Class ; rdfs:label "regulation of axon extension" ; rdfs:subClassOf obo:GO_0048638, obo:GO_0061387, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048675 ] ) ] . obo:GO_0030517 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth." ; oboInOwl:hasExactSynonym "down regulation of axon extension", "down-regulation of axon extension", "downregulation of axon extension" ; oboInOwl:hasNarrowSynonym "inhibition of axon extension" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030517" ; a owl:Class ; rdfs:label "negative regulation of axon extension" ; rdfs:subClassOf obo:GO_0030308, obo:GO_0030516, obo:GO_0048640, obo:GO_0050771, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048675 ] ) ] . obo:GO_0030534 obo:IAO_0000115 "Behavior in a fully developed and mature organism." ; oboInOwl:hasExactSynonym "adult behavioral response to stimulus", "adult behaviour", "adult behavioural response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030534" ; a owl:Class ; rdfs:comment "See also the biological process term 'behavior ; GO:0007610'." ; rdfs:label "adult behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0030537 obo:IAO_0000115 "Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics." ; oboInOwl:hasAlternativeId "GO:0017037" ; oboInOwl:hasExactSynonym "larval behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030537" ; a owl:Class ; rdfs:comment "See also the biological process term 'behavior ; GO:0007610'." ; rdfs:label "larval behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0030588 obo:IAO_0000115 "Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030588" ; a owl:Class ; rdfs:label "pseudocleavage" ; rdfs:subClassOf obo:GO_0032501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ] . obo:GO_0030590 obo:IAO_0000115 "A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030590" ; a owl:Class ; rdfs:label "first cell cycle pseudocleavage" ; rdfs:subClassOf obo:GO_0030588 . obo:GO_0030641 obo:IAO_0000115 "Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment." ; oboInOwl:hasExactSynonym "cellular hydrogen ion homeostasis", "proton homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030641" ; a owl:Class ; rdfs:label "regulation of cellular pH" ; rdfs:subClassOf obo:GO_0006885, obo:GO_0030003 . obo:GO_0030659 obo:IAO_0000115 "The lipid bilayer surrounding a cytoplasmic vesicle." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0030659" ; a owl:Class ; rdfs:label "cytoplasmic vesicle membrane" ; rdfs:subClassOf obo:GO_0012506, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031410 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031410 ] ) ] . obo:GO_0030705 obo:IAO_0000115 "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030705" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila ; a owl:Class ; rdfs:label "cytoskeleton-dependent intracellular transport" ; rdfs:subClassOf obo:GO_0046907 . obo:GO_0030728 obo:IAO_0000115 "The release of a mature ovum/oocyte from an ovary." ; oboInOwl:hasDbXref "Wikipedia:Ovulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030728" ; a owl:Class ; rdfs:label "ovulation" ; rdfs:subClassOf obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007292 ] . obo:GO_0030855 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030855" ; a owl:Class ; rdfs:label "epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060429 ] . obo:GO_0030856 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of epithelial cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030856" ; a owl:Class ; rdfs:label "regulation of epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0045595, obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030855 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030855 ] ) ] . obo:GO_0030857 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of epithelial cell differentiation", "down-regulation of epithelial cell differentiation", "downregulation of epithelial cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of epithelial cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030857" ; a owl:Class ; rdfs:label "negative regulation of epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0030856, obo:GO_0045596, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030855 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030855 ] ) ] . obo:GO_0030858 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of epithelial cell differentiation", "up-regulation of epithelial cell differentiation", "upregulation of epithelial cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of epithelial cell differentiation", "stimulation of epithelial cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0030858" ; a owl:Class ; rdfs:label "positive regulation of epithelial cell differentiation" ; rdfs:subClassOf obo:GO_0030856, obo:GO_0045597, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030855 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030855 ] ) ] . obo:GO_0030968 obo:IAO_0000115 "The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation." ; oboInOwl:hasExactSynonym "ER unfolded protein response", "erUPR" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "SREBP-mediated signalling pathway" ; oboInOwl:id "GO:0030968" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'response to unfolded protein ; GO:0006986', which refers to any response to the presence of unfolded proteins anywhere in the cell or in multicellular organism. Also see 'ER-associated protein catabolic process ; GO:0030433'." ; rdfs:label "endoplasmic reticulum unfolded protein response" ; rdfs:subClassOf obo:GO_0007165, obo:GO_0034976, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034620 ] . obo:GO_0030990 obo:IAO_0000115 "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules." ; oboInOwl:hasExactSynonym "intraflagellar transport complex", "intraflagellar transport particle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "IFT complex" ; oboInOwl:id "GO:0030990" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that we deem cilia and microtubule-based flagella to be equivalent." ; rdfs:label "intraciliary transport particle" ; rdfs:subClassOf obo:GO_0032991 . obo:GO_0031012 obo:IAO_0000115 "A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues." ; oboInOwl:hasAlternativeId "GO:0005578" ; oboInOwl:hasDbXref "NIF_Subcellular:nlx_subcell_20090513", "Wikipedia:Extracellular_matrix" ; oboInOwl:hasExactSynonym "proteinaceous extracellular matrix" ; oboInOwl:hasNarrowSynonym "matrisome" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031012" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "extracellular matrix" ; rdfs:subClassOf obo:GO_0030312 . obo:GO_0031090 obo:IAO_0000115 "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle." ; oboInOwl:hasDbXref "NIF_Subcellular:sao830981606" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "intracellular membrane" ; oboInOwl:id "GO:0031090" ; a owl:Class ; rdfs:label "organelle membrane" ; rdfs:subClassOf obo:GO_0016020, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043227 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043227 ] ) ] . obo:GO_0031109 obo:IAO_0000115 "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23195"^^xsd:anyURI ; oboInOwl:hasExactSynonym "microtubule dynamics" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031109" ; a owl:Class ; rdfs:label "microtubule polymerization or depolymerization" ; rdfs:subClassOf obo:GO_0000226 . obo:GO_0031110 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031110" ; a owl:Class ; rdfs:label "regulation of microtubule polymerization or depolymerization" ; rdfs:subClassOf obo:GO_0070507, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031109 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031109 ] ) ] . obo:GO_0031111 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization." ; oboInOwl:hasExactSynonym "down regulation of microtubule polymerization or depolymerization", "down-regulation of microtubule polymerization or depolymerization", "downregulation of microtubule polymerization or depolymerization" ; oboInOwl:hasNarrowSynonym "inhibition of microtubule polymerization or depolymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031111" ; a owl:Class ; rdfs:label "negative regulation of microtubule polymerization or depolymerization" ; rdfs:subClassOf obo:GO_0031110, obo:GO_0051494, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031109 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031109 ] ) ] . obo:GO_0031112 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization." ; oboInOwl:hasExactSynonym "up regulation of microtubule polymerization or depolymerization", "up-regulation of microtubule polymerization or depolymerization", "upregulation of microtubule polymerization or depolymerization" ; oboInOwl:hasNarrowSynonym "activation of microtubule polymerization or depolymerization", "stimulation of microtubule polymerization or depolymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031112" ; a owl:Class ; rdfs:label "positive regulation of microtubule polymerization or depolymerization" ; rdfs:subClassOf obo:GO_0031110, obo:GO_0051495, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031109 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031109 ] ) ] . obo:GO_0031113 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of microtubule polymerization." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031113" ; a owl:Class ; rdfs:label "regulation of microtubule polymerization" ; rdfs:subClassOf obo:GO_0031110, obo:GO_0032271, obo:GO_1902903, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046785 ] ) ] . obo:GO_0031114 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of microtubule depolymerization." ; oboInOwl:hasExactSynonym "regulation of microtubule disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031114" ; a owl:Class ; rdfs:label "regulation of microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031110, obo:GO_1901879, obo:GO_1902903, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007019 ] ) ] . obo:GO_0031115 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization." ; oboInOwl:hasExactSynonym "down regulation of microtubule polymerization", "down-regulation of microtubule polymerization", "downregulation of microtubule polymerization" ; oboInOwl:hasNarrowSynonym "inhibition of microtubule polymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031115" ; a owl:Class ; rdfs:label "negative regulation of microtubule polymerization" ; rdfs:subClassOf obo:GO_0031111, obo:GO_0031113, obo:GO_0032272, obo:GO_1902904, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046785 ] ) ] . obo:GO_0031116 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of microtubule polymerization." ; oboInOwl:hasExactSynonym "up regulation of microtubule polymerization", "up-regulation of microtubule polymerization", "upregulation of microtubule polymerization" ; oboInOwl:hasNarrowSynonym "activation of microtubule polymerization", "stimulation of microtubule polymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031116" ; a owl:Class ; rdfs:label "positive regulation of microtubule polymerization" ; rdfs:subClassOf obo:GO_0031112, obo:GO_0031113, obo:GO_0032273, obo:GO_1902905, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046785 ] ) ] . obo:GO_0031117 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization." ; oboInOwl:hasExactSynonym "microtubule destabilization", "positive regulation of microtubule disassembly", "up regulation of microtubule depolymerization", "up-regulation of microtubule depolymerization", "upregulation of microtubule depolymerization" ; oboInOwl:hasNarrowSynonym "activation of microtubule depolymerization", "positive regulation of microtubule catastrophe", "stimulation of microtubule depolymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031117" ; a owl:Class ; rdfs:label "positive regulation of microtubule depolymerization" ; rdfs:subClassOf obo:GO_0031112, obo:GO_0031114, obo:GO_1901881, obo:GO_1902905, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007019 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007019 ] ) ] . obo:GO_0031122 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell." ; oboInOwl:hasExactSynonym "cytoplasmic microtubule organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cytoplasmic microtubule organization and biogenesis" ; oboInOwl:id "GO:0031122" ; a owl:Class ; rdfs:label "cytoplasmic microtubule organization" ; rdfs:subClassOf obo:GO_0000226, obo:GO_0097435 . obo:GO_0031128 obo:IAO_0000115 "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder)." ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031128" ; a owl:Class ; rdfs:label "developmental induction" ; rdfs:subClassOf obo:GO_0032502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0045168 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0045168 ] ) ] . obo:GO_0031129 obo:IAO_0000115 "Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate." ; oboInOwl:hasExactSynonym "inductive cell-cell signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031129" ; a owl:Class ; rdfs:label "inductive cell-cell signaling" ; rdfs:subClassOf obo:GO_0031128 . obo:GO_0031143 obo:IAO_0000115 "A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21139"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/21141"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Pseudopod" ; oboInOwl:hasExactSynonym "pseudopod", "pseudopodial protrusion" ; oboInOwl:hasNarrowSynonym "axopodium", "lobopodium", "reticulopodium" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031143" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "pseudopodium" ; rdfs:subClassOf obo:GO_0120025 . obo:GO_0031175 obo:IAO_0000115 "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites)." ; oboInOwl:hasNarrowSynonym "neurite biosynthesis", "neurite development", "neurite formation", "neurite growth", "neurite outgrowth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031175" ; a owl:Class ; rdfs:label "neuron projection development" ; rdfs:subClassOf obo:GO_0120036, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0120036 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ] ) ] . obo:GO_0031323 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." ; oboInOwl:hasExactSynonym "regulation of cellular metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031323" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "regulation of cellular metabolic process" ; rdfs:subClassOf obo:GO_0019222, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044237 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044237 ] ) ] . obo:GO_0031324 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." ; oboInOwl:hasExactSynonym "down regulation of cellular metabolic process", "down-regulation of cellular metabolic process", "downregulation of cellular metabolic process", "negative regulation of cellular metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of cellular metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031324" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of cellular metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0031323, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044237 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044237 ] ) ] . obo:GO_0031325 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances." ; oboInOwl:hasExactSynonym "positive regulation of cellular metabolism", "up regulation of cellular metabolic process", "up-regulation of cellular metabolic process", "upregulation of cellular metabolic process" ; oboInOwl:hasNarrowSynonym "activation of cellular metabolic process", "stimulation of cellular metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031325" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of cellular metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0031323, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044237 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044237 ] ) ] . obo:GO_0031326 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "regulation of cellular anabolism", "regulation of cellular biosynthesis", "regulation of cellular formation", "regulation of cellular synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031326" ; a owl:Class ; rdfs:label "regulation of cellular biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0031323, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044249 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044249 ] ) ] . obo:GO_0031327 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "down regulation of cellular biosynthetic process", "down-regulation of cellular biosynthetic process", "downregulation of cellular biosynthetic process", "negative regulation of cellular anabolism", "negative regulation of cellular biosynthesis", "negative regulation of cellular formation", "negative regulation of cellular synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of cellular biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031327" ; a owl:Class ; rdfs:label "negative regulation of cellular biosynthetic process" ; rdfs:subClassOf obo:GO_0009890, obo:GO_0031324, obo:GO_0031326, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044249 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044249 ] ) ] . obo:GO_0031328 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "positive regulation of cellular anabolism", "positive regulation of cellular biosynthesis", "positive regulation of cellular formation", "positive regulation of cellular synthesis", "up regulation of cellular biosynthetic process", "up-regulation of cellular biosynthetic process", "upregulation of cellular biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of cellular biosynthetic process", "stimulation of cellular biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031328" ; a owl:Class ; rdfs:label "positive regulation of cellular biosynthetic process" ; rdfs:subClassOf obo:GO_0009891, obo:GO_0031325, obo:GO_0031326, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044249 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044249 ] ) ] . obo:GO_0031329 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "regulation of cellular breakdown", "regulation of cellular catabolism", "regulation of cellular degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031329" ; a owl:Class ; rdfs:label "regulation of cellular catabolic process" ; rdfs:subClassOf obo:GO_0009894, obo:GO_0031323, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044248 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044248 ] ) ] . obo:GO_0031330 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "down regulation of cellular catabolic process", "down-regulation of cellular catabolic process", "downregulation of cellular catabolic process", "negative regulation of cellular breakdown", "negative regulation of cellular catabolism", "negative regulation of cellular degradation" ; oboInOwl:hasNarrowSynonym "inhibition of cellular catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031330" ; a owl:Class ; rdfs:label "negative regulation of cellular catabolic process" ; rdfs:subClassOf obo:GO_0009895, obo:GO_0031324, obo:GO_0031329, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044248 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044248 ] ) ] . obo:GO_0031331 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "positive regulation of cellular breakdown", "positive regulation of cellular catabolism", "positive regulation of cellular degradation", "up regulation of cellular catabolic process", "up-regulation of cellular catabolic process", "upregulation of cellular catabolic process" ; oboInOwl:hasNarrowSynonym "activation of cellular catabolic process", "stimulation of cellular catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031331" ; a owl:Class ; rdfs:label "positive regulation of cellular catabolic process" ; rdfs:subClassOf obo:GO_0009896, obo:GO_0031325, obo:GO_0031329, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044248 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044248 ] ) ] . obo:GO_0031333 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly." ; oboInOwl:hasExactSynonym "down regulation of protein complex assembly", "down-regulation of protein complex assembly", "downregulation of protein complex assembly" ; oboInOwl:hasNarrowSynonym "inhibition of protein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of protein complex assembly" ; oboInOwl:id "GO:0031333" ; a owl:Class ; rdfs:label "negative regulation of protein-containing complex assembly" ; rdfs:subClassOf obo:GO_0043254, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0065003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0065003 ] ) ] . obo:GO_0031334 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein complex assembly." ; oboInOwl:hasExactSynonym "up regulation of protein complex assembly", "up-regulation of protein complex assembly", "upregulation of protein complex assembly" ; oboInOwl:hasNarrowSynonym "activation of protein complex assembly", "stimulation of protein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of protein complex assembly" ; oboInOwl:id "GO:0031334" ; a owl:Class ; rdfs:label "positive regulation of protein-containing complex assembly" ; rdfs:subClassOf obo:GO_0043254, obo:GO_0044089, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0065003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0065003 ] ) ] . obo:GO_0031338 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of vesicle fusion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031338" ; a owl:Class ; rdfs:label "regulation of vesicle fusion" ; rdfs:subClassOf obo:GO_0033043, obo:GO_0060627, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006906 ] ) ] . obo:GO_0031339 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion." ; oboInOwl:hasExactSynonym "down regulation of vesicle fusion", "down-regulation of vesicle fusion", "downregulation of vesicle fusion" ; oboInOwl:hasNarrowSynonym "inhibition of vesicle fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031339" ; a owl:Class ; rdfs:label "negative regulation of vesicle fusion" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0031338, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006906 ] ) ] . obo:GO_0031340 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of vesicle fusion." ; oboInOwl:hasExactSynonym "up regulation of vesicle fusion", "up-regulation of vesicle fusion", "upregulation of vesicle fusion" ; oboInOwl:hasNarrowSynonym "activation of vesicle fusion", "stimulation of vesicle fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031340" ; a owl:Class ; rdfs:label "positive regulation of vesicle fusion" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0031338, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006906 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006906 ] ) ] . obo:GO_0031344 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ; oboInOwl:hasExactSynonym "regulation of cell projection organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cell projection organization and biogenesis" ; oboInOwl:id "GO:0031344" ; a owl:Class ; rdfs:label "regulation of cell projection organization" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030030 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030030 ] ) ] . obo:GO_0031345 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ; oboInOwl:hasExactSynonym "down regulation of cell projection organization", "down-regulation of cell projection organization", "downregulation of cell projection organization", "negative regulation of cell projection organisation" ; oboInOwl:hasNarrowSynonym "inhibition of cell projection organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell projection organization and biogenesis" ; oboInOwl:id "GO:0031345" ; a owl:Class ; rdfs:label "negative regulation of cell projection organization" ; rdfs:subClassOf obo:GO_0031344, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030030 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030030 ] ) ] . obo:GO_0031346 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections." ; oboInOwl:hasExactSynonym "positive regulation of cell projection organisation", "up regulation of cell projection organization", "up-regulation of cell projection organization", "upregulation of cell projection organization" ; oboInOwl:hasNarrowSynonym "activation of cell projection organization", "stimulation of cell projection organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cell projection organization and biogenesis" ; oboInOwl:id "GO:0031346" ; a owl:Class ; rdfs:label "positive regulation of cell projection organization" ; rdfs:subClassOf obo:GO_0031344, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030030 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030030 ] ) ] . obo:GO_0031347 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a defense response." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031347" ; a owl:Class ; rdfs:label "regulation of defense response" ; rdfs:subClassOf obo:GO_0080134, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006952 ] ) ] . obo:GO_0031348 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response." ; oboInOwl:hasExactSynonym "down regulation of defense response", "down-regulation of defense response", "downregulation of defense response" ; oboInOwl:hasNarrowSynonym "inhibition of defense response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031348" ; a owl:Class ; rdfs:label "negative regulation of defense response" ; rdfs:subClassOf obo:GO_0031347, obo:GO_0048585, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006952 ] ) ] . obo:GO_0031349 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a defense response." ; oboInOwl:hasExactSynonym "up regulation of defense response", "up-regulation of defense response", "upregulation of defense response" ; oboInOwl:hasNarrowSynonym "activation of defense response", "stimulation of defense response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031349" ; a owl:Class ; rdfs:label "positive regulation of defense response" ; rdfs:subClassOf obo:GO_0031347, obo:GO_0048584, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006952 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006952 ] ) ] . obo:GO_0031399 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031399" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of protein modification process" ; rdfs:subClassOf obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0036211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0036211 ] ) ] . obo:GO_0031400 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ; oboInOwl:hasExactSynonym "down regulation of protein modification", "down-regulation of protein modification", "downregulation of protein modification" ; oboInOwl:hasNarrowSynonym "inhibition of protein modification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031400" ; a owl:Class ; rdfs:label "negative regulation of protein modification process" ; rdfs:subClassOf obo:GO_0031399, obo:GO_0051248, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0036211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0036211 ] ) ] . obo:GO_0031401 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein." ; oboInOwl:hasExactSynonym "up regulation of protein modification", "up-regulation of protein modification", "upregulation of protein modification" ; oboInOwl:hasNarrowSynonym "activation of protein modification", "stimulation of protein modification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031401" ; a owl:Class ; rdfs:label "positive regulation of protein modification process" ; rdfs:subClassOf obo:GO_0031399, obo:GO_0051247, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0036211 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0036211 ] ) ] . obo:GO_0031410 obo:IAO_0000115 "A vesicle found in the cytoplasm of a cell." ; oboInOwl:hasAlternativeId "GO:0016023" ; oboInOwl:hasDbXref "NIF_Subcellular:sao180601769" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cytoplasmic membrane bounded vesicle", "cytoplasmic membrane-enclosed vesicle", "cytoplasmic, membrane-bounded vesicle" ; oboInOwl:id "GO:0031410" ; oboInOwl:inSubset go:goslim_agr, go:goslim_candida, go:goslim_chembl, go:goslim_generic, go:goslim_mouse, go:goslim_yeast ; a owl:Class ; rdfs:label "cytoplasmic vesicle" ; rdfs:subClassOf obo:GO_0097708, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031982 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0031430 obo:IAO_0000115 "The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines." ; oboInOwl:hasBroadSynonym "midline" ; oboInOwl:hasDbXref "Wikipedia:Sarcomere#bands" ; oboInOwl:hasExactSynonym "M disc", "mesophragma" ; oboInOwl:hasNarrowSynonym "M line" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031430" ; a owl:Class ; rdfs:label "M band" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031672 ] . obo:GO_0031468 obo:IAO_0000115 "The reformation of the nuclear membranes following their breakdown in the context of a normal process." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20636"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear envelope reassembly" ; oboInOwl:id "GO:0031468" ; a owl:Class ; rdfs:label "nuclear membrane reassembly" ; rdfs:subClassOf obo:GO_0071709, obo:GO_0071763 . obo:GO_0031503 obo:IAO_0000115 "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0034629" ; oboInOwl:hasExactSynonym "establishment and maintenance of protein complex localization", "protein complex localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular protein complex localisation", "cellular protein complex localization", "cellular protein-containing complex localization", "establishment and maintenance of cellular protein complex localization", "protein complex localization" ; oboInOwl:id "GO:0031503" ; a owl:Class ; rdfs:label "protein-containing complex localization" ; rdfs:subClassOf obo:GO_0051179 . obo:GO_0031570 obo:IAO_0000115 "A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072401" ; oboInOwl:hasExactSynonym "DNA integrity checkpoint", "signal transduction involved in DNA integrity checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031570" ; a owl:Class ; rdfs:label "DNA integrity checkpoint signaling" ; rdfs:subClassOf obo:GO_0000075 . obo:GO_0031573 obo:IAO_0000115 "A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072428" ; oboInOwl:hasBroadSynonym "S-phase checkpoint" ; oboInOwl:hasExactSynonym "intra-S DNA damage checkpoint", "mitotic intra-S DNA damage checkpoint", "signal transduction involved in intra-S DNA damage checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031573" ; a owl:Class ; rdfs:label "mitotic intra-S DNA damage checkpoint signaling" ; rdfs:subClassOf obo:GO_0044773, [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000084 ] . obo:GO_0031577 obo:IAO_0000115 "A signaling process that that controls a cell cycle checkpoint that originates from the mitotic or meiotic spindle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072416" ; oboInOwl:hasDbXref "Wikipedia:Spindle_checkpoint" ; oboInOwl:hasExactSynonym "signal transduction involved in spindle checkpoint", "spindle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031577" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to choose either a mitotic or meiotic child term." ; rdfs:label "spindle checkpoint signaling" ; rdfs:subClassOf obo:GO_0000075 . obo:GO_0031644 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system." ; oboInOwl:hasExactSynonym "regulation of neurological process", "regulation of neurological system process", "regulation of neurophysiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031644" ; a owl:Class ; rdfs:label "regulation of nervous system process" ; rdfs:subClassOf obo:GO_0044057, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050877 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050877 ] ) ] . obo:GO_0031645 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process." ; oboInOwl:hasExactSynonym "down regulation of neurological process", "down-regulation of neurological process", "downregulation of neurological process", "negative regulation of neurological process", "negative regulation of neurological system process", "negative regulation of neurophysiological process" ; oboInOwl:hasNarrowSynonym "inhibition of neurological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031645" ; a owl:Class ; rdfs:label "negative regulation of nervous system process" ; rdfs:subClassOf obo:GO_0031644, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050877 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050877 ] ) ] . obo:GO_0031646 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a neurophysiological process." ; oboInOwl:hasExactSynonym "positive regulation of neurological process", "positive regulation of neurological system process", "positive regulation of neurophysiological process", "up regulation of neurological process", "up-regulation of neurological process", "upregulation of neurological process" ; oboInOwl:hasNarrowSynonym "activation of neurological process", "stimulation of neurological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031646" ; a owl:Class ; rdfs:label "positive regulation of nervous system process" ; rdfs:subClassOf obo:GO_0031644, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050877 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050877 ] ) ] . obo:GO_0031647 obo:IAO_0000115 "Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031647" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "regulation of protein stability" ; rdfs:subClassOf obo:GO_0065008 . obo:GO_0031667 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031667" ; a owl:Class ; rdfs:label "response to nutrient levels" ; rdfs:subClassOf obo:GO_0009991 . obo:GO_0031672 obo:IAO_0000115 "The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line." ; oboInOwl:hasDbXref "Wikipedia:Sarcomere#bands" ; oboInOwl:hasExactSynonym "A disc", "Q disc", "anisotropic disc", "transverse disc" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031672" ; a owl:Class ; rdfs:label "A band" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030017 ] . obo:GO_0031965 obo:IAO_0000115 "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1687101204" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031965" ; a owl:Class ; rdfs:label "nuclear membrane" ; rdfs:subClassOf obo:GO_0031090, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005635 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0031966 obo:IAO_0000115 "Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1045389829" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031966" ; a owl:Class ; rdfs:label "mitochondrial membrane" ; rdfs:subClassOf obo:GO_0031090, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005740 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0031967 obo:IAO_0000115 "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031967" ; oboInOwl:inSubset go:goslim_mouse ; a owl:Class ; rdfs:label "organelle envelope" ; rdfs:subClassOf obo:GO_0031975, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043227 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043229 ] . obo:GO_0031974 obo:IAO_0000115 "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031974" ; a owl:Class ; rdfs:label "membrane-enclosed lumen" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0031975 obo:IAO_0000115 "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031975" ; a owl:Class ; rdfs:label "envelope" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0031981 obo:IAO_0000115 "The volume enclosed by the nuclear inner membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0031981" ; a owl:Class ; rdfs:label "nuclear lumen" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] . obo:GO_0031982 obo:IAO_0000115 "Any small, fluid-filled, spherical organelle enclosed by membrane." ; oboInOwl:hasAlternativeId "GO:0031988" ; oboInOwl:hasDbXref "NIF_Subcellular:sao221389602", "Wikipedia:Vesicle_(biology)" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "membrane-bounded vesicle", "membrane-enclosed vesicle" ; oboInOwl:id "GO:0031982" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "vesicle" ; rdfs:subClassOf obo:GO_0043227 . obo:GO_0031987 obo:IAO_0000115 "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ; oboInOwl:hasExactSynonym "locomotion during locomotory behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0031987" ; a owl:Class ; rdfs:label "locomotion involved in locomotory behavior" ; rdfs:subClassOf obo:GO_0040011, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007626 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040011 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007626 ] ) ] . obo:GO_0032042 obo:IAO_0000115 "The chemical reactions and pathways involving mitochondrial DNA." ; oboInOwl:hasExactSynonym "mitochondrial DNA metabolism", "mtDNA metabolic process", "mtDNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032042" ; a owl:Class ; rdfs:label "mitochondrial DNA metabolic process" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0006259, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000002 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006259 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0032055 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress." ; oboInOwl:hasExactSynonym "down regulation of translation in response to stress", "down-regulation of translation in response to stress", "downregulation of translation in response to stress" ; oboInOwl:hasNarrowSynonym "inhibition of translation in response to stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032055" ; a owl:Class ; rdfs:label "negative regulation of translation in response to stress" ; rdfs:subClassOf obo:GO_0017148, obo:GO_0043555 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032056 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress." ; oboInOwl:hasExactSynonym "up regulation of translation in response to stress", "up-regulation of translation in response to stress", "upregulation of translation in response to stress" ; oboInOwl:hasNarrowSynonym "activation of translation in response to stress", "stimulation of translation in response to stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032056" ; a owl:Class ; rdfs:label "positive regulation of translation in response to stress" ; rdfs:subClassOf obo:GO_0043555, obo:GO_0045727 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032061 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:hasExactSynonym "down regulation of translation in response to osmotic stress", "down-regulation of translation in response to osmotic stress", "downregulation of translation in response to osmotic stress" ; oboInOwl:hasNarrowSynonym "inhibition of translation in response to osmotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032061" ; a owl:Class ; rdfs:label "negative regulation of translation in response to osmotic stress" ; rdfs:subClassOf obo:GO_0032055, obo:GO_0043557 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071470 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032062 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:hasExactSynonym "up regulation of translation in response to osmotic stress", "up-regulation of translation in response to osmotic stress", "upregulation of translation in response to osmotic stress" ; oboInOwl:hasNarrowSynonym "activation of translation in response to osmotic stress", "stimulation of translation in response to osmotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032062" ; a owl:Class ; rdfs:label "positive regulation of translation in response to osmotic stress" ; rdfs:subClassOf obo:GO_0032056, obo:GO_0043557 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071470 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032065 obo:IAO_0000115 "A process in which a protein or protein complex is maintained in a specific location in the cell cortex." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cortical protein anchoring" ; oboInOwl:id "GO:0032065" ; a owl:Class ; rdfs:label "maintenance of protein location in cell cortex" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0032507, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005938 ] ) ] . obo:GO_0032091 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding." ; oboInOwl:hasExactSynonym "down regulation of protein binding", "down-regulation of protein binding", "downregulation of protein binding" ; oboInOwl:hasNarrowSynonym "inhibition of protein binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032091" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of protein binding" ; rdfs:subClassOf obo:GO_0043393, obo:GO_0051100, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005515 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005515 ] ) ] . obo:GO_0032092 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein binding." ; oboInOwl:hasExactSynonym "up regulation of protein binding", "up-regulation of protein binding", "upregulation of protein binding" ; oboInOwl:hasNarrowSynonym "activation of protein binding", "stimulation of protein binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032092" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of protein binding" ; rdfs:subClassOf obo:GO_0043393, obo:GO_0051099, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005515 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005515 ] ) ] . obo:GO_0032094 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032094" ; a owl:Class ; rdfs:label "response to food" ; rdfs:subClassOf obo:GO_0031667, obo:GO_0042221 . obo:GO_0032095 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to a food stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032095" ; a owl:Class ; rdfs:label "regulation of response to food" ; rdfs:subClassOf obo:GO_0032107, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032094 ] ) ] . obo:GO_0032096 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to food", "down-regulation of response to food", "downregulation of response to food" ; oboInOwl:hasNarrowSynonym "inhibition of response to food" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032096" ; a owl:Class ; rdfs:label "negative regulation of response to food" ; rdfs:subClassOf obo:GO_0032095, obo:GO_0032108, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032094 ] ) ] . obo:GO_0032097 obo:IAO_0000115 "Any process that activates, maintains, or increases the rate of a response to a food stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to food", "up-regulation of response to food", "upregulation of response to food" ; oboInOwl:hasNarrowSynonym "activation of response to food", "stimulation of response to food" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032097" ; a owl:Class ; rdfs:label "positive regulation of response to food" ; rdfs:subClassOf obo:GO_0032095, obo:GO_0032109, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032094 ] ) ] . obo:GO_0032101 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to an external stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032101" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "regulation of response to external stimulus" ; rdfs:subClassOf obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009605 ] ) ] . obo:GO_0032102 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to external stimulus", "down-regulation of response to external stimulus", "downregulation of response to external stimulus" ; oboInOwl:hasNarrowSynonym "inhibition of response to external stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032102" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "negative regulation of response to external stimulus" ; rdfs:subClassOf obo:GO_0032101, obo:GO_0048585, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009605 ] ) ] . obo:GO_0032103 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of a response to an external stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to external stimulus", "up-regulation of response to external stimulus", "upregulation of response to external stimulus" ; oboInOwl:hasNarrowSynonym "activation of response to external stimulus", "stimulation of response to external stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032103" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "positive regulation of response to external stimulus" ; rdfs:subClassOf obo:GO_0032101, obo:GO_0048584, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009605 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009605 ] ) ] . obo:GO_0032104 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032104" ; a owl:Class ; rdfs:label "regulation of response to extracellular stimulus" ; rdfs:subClassOf obo:GO_0032101, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009991 ] ) ] . obo:GO_0032105 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to extracellular stimulus", "down-regulation of response to extracellular stimulus", "downregulation of response to extracellular stimulus" ; oboInOwl:hasNarrowSynonym "inhibition of response to extracellular stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032105" ; a owl:Class ; rdfs:label "negative regulation of response to extracellular stimulus" ; rdfs:subClassOf obo:GO_0032102, obo:GO_0032104, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009991 ] ) ] . obo:GO_0032106 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of a response to an extracellular stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to extracellular stimulus", "up-regulation of response to extracellular stimulus", "upregulation of response to extracellular stimulus" ; oboInOwl:hasNarrowSynonym "activation of response to extracellular stimulus", "stimulation of response to extracellular stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032106" ; a owl:Class ; rdfs:label "positive regulation of response to extracellular stimulus" ; rdfs:subClassOf obo:GO_0032103, obo:GO_0032104, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009991 ] ) ] . obo:GO_0032107 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to nutrient levels." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032107" ; a owl:Class ; rdfs:label "regulation of response to nutrient levels" ; rdfs:subClassOf obo:GO_0032104, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031667 ] ) ] . obo:GO_0032108 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels." ; oboInOwl:hasExactSynonym "down regulation of response to nutrient levels", "down-regulation of response to nutrient levels", "downregulation of response to nutrient levels" ; oboInOwl:hasNarrowSynonym "inhibition of response to nutrient levels" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032108" ; a owl:Class ; rdfs:label "negative regulation of response to nutrient levels" ; rdfs:subClassOf obo:GO_0032105, obo:GO_0032107, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031667 ] ) ] . obo:GO_0032109 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a response to nutrient levels." ; oboInOwl:hasExactSynonym "up regulation of response to nutrient levels", "up-regulation of response to nutrient levels", "upregulation of response to nutrient levels" ; oboInOwl:hasNarrowSynonym "activation of response to nutrient levels", "stimulation of response to nutrient levels" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032109" ; a owl:Class ; rdfs:label "positive regulation of response to nutrient levels" ; rdfs:subClassOf obo:GO_0032106, obo:GO_0032107, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031667 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031667 ] ) ] . obo:GO_0032153 obo:IAO_0000115 "The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles." ; oboInOwl:hasExactSynonym "cell division plane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032153" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:comment "Note that this term refers to the future site of division in a cell that has not yet divided." ; rdfs:label "cell division site" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0032154 obo:IAO_0000115 "The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm." ; oboInOwl:hasDbXref "Wikipedia:Cleavage_furrow" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032154" ; a owl:Class ; rdfs:comment "While the term 'cleavage furrow' was initially associated with animal cells, such a structure occurs in many other types of cells, including unicellular protists." ; rdfs:label "cleavage furrow" ; rdfs:subClassOf obo:GO_0098590, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032153 ] . obo:GO_0032200 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins." ; oboInOwl:hasExactSynonym "chromosome organization, telomeric", "organization of chromosome, telomeric region", "telomere organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "telomere organization and biogenesis" ; oboInOwl:id "GO:0032200" ; oboInOwl:inSubset go:goslim_generic, go:goslim_pombe, go:goslim_yeast ; a owl:Class ; rdfs:label "telomere organization" ; rdfs:subClassOf obo:GO_0051276 . obo:GO_0032204 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032204" ; a owl:Class ; rdfs:label "regulation of telomere maintenance" ; rdfs:subClassOf obo:GO_0033044, obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000723 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000723 ] ) ] . obo:GO_0032205 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." ; oboInOwl:hasExactSynonym "down regulation of telomere maintenance", "down-regulation of telomere maintenance", "downregulation of telomere maintenance" ; oboInOwl:hasNarrowSynonym "inhibition of telomere maintenance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032205" ; a owl:Class ; rdfs:label "negative regulation of telomere maintenance" ; rdfs:subClassOf obo:GO_0032204, obo:GO_0051053, obo:GO_2001251, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000723 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000723 ] ) ] . obo:GO_0032206 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA." ; oboInOwl:hasExactSynonym "up regulation of telomere maintenance", "up-regulation of telomere maintenance", "upregulation of telomere maintenance" ; oboInOwl:hasNarrowSynonym "activation of telomere maintenance", "stimulation of telomere maintenance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032206" ; a owl:Class ; rdfs:label "positive regulation of telomere maintenance" ; rdfs:subClassOf obo:GO_0032204, obo:GO_0051054, obo:GO_2001252, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000723 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000723 ] ) ] . obo:GO_0032222 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032222" ; a owl:Class ; rdfs:label "regulation of synaptic transmission, cholinergic" ; rdfs:subClassOf obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007271 ] ) ] . obo:GO_0032223 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ; oboInOwl:hasExactSynonym "down regulation of synaptic transmission, cholinergic", "down-regulation of synaptic transmission, cholinergic", "downregulation of synaptic transmission, cholinergic" ; oboInOwl:hasNarrowSynonym "inhibition of synaptic transmission, cholinergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032223" ; a owl:Class ; rdfs:label "negative regulation of synaptic transmission, cholinergic" ; rdfs:subClassOf obo:GO_0032222, obo:GO_0050805, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007271 ] ) ] . obo:GO_0032224 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine." ; oboInOwl:hasExactSynonym "up regulation of synaptic transmission, cholinergic", "up-regulation of synaptic transmission, cholinergic", "upregulation of synaptic transmission, cholinergic" ; oboInOwl:hasNarrowSynonym "activation of synaptic transmission, cholinergic", "stimulation of synaptic transmission, cholinergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032224" ; a owl:Class ; rdfs:label "positive regulation of synaptic transmission, cholinergic" ; rdfs:subClassOf obo:GO_0032222, obo:GO_0050806, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007271 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007271 ] ) ] . obo:GO_0032228 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032228" ; a owl:Class ; rdfs:label "regulation of synaptic transmission, GABAergic" ; rdfs:subClassOf obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051932 ] ) ] . obo:GO_0032229 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ; oboInOwl:hasExactSynonym "down regulation of synaptic transmission, GABAergic", "down-regulation of synaptic transmission, GABAergic", "downregulation of synaptic transmission, GABAergic" ; oboInOwl:hasNarrowSynonym "inhibition of synaptic transmission, GABAergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032229" ; a owl:Class ; rdfs:label "negative regulation of synaptic transmission, GABAergic" ; rdfs:subClassOf obo:GO_0032228, obo:GO_0050805, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051932 ] ) ] . obo:GO_0032230 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA)." ; oboInOwl:hasExactSynonym "up regulation of synaptic transmission, GABAergic", "up-regulation of synaptic transmission, GABAergic", "upregulation of synaptic transmission, GABAergic" ; oboInOwl:hasNarrowSynonym "activation of synaptic transmission, GABAergic", "stimulation of synaptic transmission, GABAergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032230" ; a owl:Class ; rdfs:label "positive regulation of synaptic transmission, GABAergic" ; rdfs:subClassOf obo:GO_0032228, obo:GO_0050806, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051932 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051932 ] ) ] . obo:GO_0032239 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:id "GO:0032239" ; a owl:Class ; rdfs:label "regulation of nucleobase-containing compound transport" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015931 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015931 ] ) ] . obo:GO_0032240 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:hasNarrowSynonym "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:id "GO:0032240" ; a owl:Class ; rdfs:label "negative regulation of nucleobase-containing compound transport" ; rdfs:subClassOf obo:GO_0032239, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015931 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015931 ] ) ] . obo:GO_0032241 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:hasNarrowSynonym "activation of nucleobase, nucleoside, nucleotide and nucleic acid transport", "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport" ; oboInOwl:id "GO:0032241" ; a owl:Class ; rdfs:label "positive regulation of nucleobase-containing compound transport" ; rdfs:subClassOf obo:GO_0032239, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015931 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015931 ] ) ] . obo:GO_0032259 obo:IAO_0000115 "The process in which a methyl group is covalently attached to a molecule." ; oboInOwl:hasDbXref "Wikipedia:Methylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032259" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "methylation" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0032271 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the process of creating protein polymers." ; oboInOwl:hasExactSynonym "regulation of protein polymerisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032271" ; a owl:Class ; rdfs:label "regulation of protein polymerization" ; rdfs:subClassOf obo:GO_0043254, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051258 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051258 ] ) ] . obo:GO_0032272 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers." ; oboInOwl:hasExactSynonym "down regulation of protein polymerization", "down-regulation of protein polymerization", "downregulation of protein polymerization" ; oboInOwl:hasNarrowSynonym "inhibition of protein polymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032272" ; a owl:Class ; rdfs:label "negative regulation of protein polymerization" ; rdfs:subClassOf obo:GO_0031333, obo:GO_0032271, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051258 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051258 ] ) ] . obo:GO_0032273 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers." ; oboInOwl:hasExactSynonym "up regulation of protein polymerization", "up-regulation of protein polymerization", "upregulation of protein polymerization" ; oboInOwl:hasNarrowSynonym "activation of protein polymerization", "stimulation of protein polymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032273" ; a owl:Class ; rdfs:label "positive regulation of protein polymerization" ; rdfs:subClassOf obo:GO_0031334, obo:GO_0032271, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051258 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051258 ] ) ] . obo:GO_0032297 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication." ; oboInOwl:hasBroadSynonym "negative regulation of DNA replication initiation" ; oboInOwl:hasExactSynonym "down regulation of DNA replication initiation", "down-regulation of DNA replication initiation", "downregulation of DNA replication initiation", "negative regulation of DNA-dependent DNA replication initiation" ; oboInOwl:hasNarrowSynonym "inhibition of DNA replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032297" ; a owl:Class ; rdfs:label "negative regulation of DNA-templated DNA replication initiation" ; rdfs:subClassOf obo:GO_0030174, obo:GO_2000104, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006270 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006270 ] ) ] . obo:GO_0032298 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication." ; oboInOwl:hasBroadSynonym "negative regulation of DNA replication initiation" ; oboInOwl:hasExactSynonym "positive regulation of DNA-dependent DNA replication initiation", "up regulation of DNA replication initiation", "up-regulation of DNA replication initiation", "upregulation of DNA replication initiation" ; oboInOwl:hasNarrowSynonym "activation of DNA replication initiation", "stimulation of DNA replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032298" ; a owl:Class ; rdfs:label "positive regulation of DNA-templated DNA replication initiation" ; rdfs:subClassOf obo:GO_0030174, obo:GO_2000105, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006270 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006270 ] ) ] . obo:GO_0032350 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ; oboInOwl:hasExactSynonym "regulation of hormone metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032350" ; a owl:Class ; rdfs:label "regulation of hormone metabolic process" ; rdfs:subClassOf obo:GO_0010817, obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042445 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042445 ] ) ] . obo:GO_0032351 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ; oboInOwl:hasExactSynonym "down regulation of hormone metabolic process", "down-regulation of hormone metabolic process", "downregulation of hormone metabolic process", "negative regulation of hormone metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of hormone metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032351" ; a owl:Class ; rdfs:label "negative regulation of hormone metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0032350, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042445 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042445 ] ) ] . obo:GO_0032352 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone." ; oboInOwl:hasExactSynonym "positive regulation of hormone metabolism", "up regulation of hormone metabolic process", "up-regulation of hormone metabolic process", "upregulation of hormone metabolic process" ; oboInOwl:hasNarrowSynonym "activation of hormone metabolic process", "stimulation of hormone metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032352" ; a owl:Class ; rdfs:label "positive regulation of hormone metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0032350, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042445 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042445 ] ) ] . obo:GO_0032386 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032386" ; a owl:Class ; rdfs:label "regulation of intracellular transport" ; rdfs:subClassOf obo:GO_0051049, obo:GO_0060341, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046907 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046907 ] ) ] . obo:GO_0032387 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells." ; oboInOwl:hasExactSynonym "down regulation of intracellular transport", "down-regulation of intracellular transport", "downregulation of intracellular transport" ; oboInOwl:hasNarrowSynonym "inhibition of intracellular transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032387" ; a owl:Class ; rdfs:label "negative regulation of intracellular transport" ; rdfs:subClassOf obo:GO_0032386, obo:GO_0048523, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046907 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046907 ] ) ] . obo:GO_0032388 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells." ; oboInOwl:hasExactSynonym "up regulation of intracellular transport", "up-regulation of intracellular transport", "upregulation of intracellular transport" ; oboInOwl:hasNarrowSynonym "activation of intracellular transport", "stimulation of intracellular transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032388" ; a owl:Class ; rdfs:label "positive regulation of intracellular transport" ; rdfs:subClassOf obo:GO_0032386, obo:GO_0048522, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046907 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046907 ] ) ] . obo:GO_0032459 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein oligomerization." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032459" ; a owl:Class ; rdfs:label "regulation of protein oligomerization" ; rdfs:subClassOf obo:GO_0043254, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051259 ] ) ] . obo:GO_0032460 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization." ; oboInOwl:hasExactSynonym "down regulation of protein oligomerization", "down-regulation of protein oligomerization", "downregulation of protein oligomerization" ; oboInOwl:hasNarrowSynonym "inhibition of protein oligomerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032460" ; a owl:Class ; rdfs:label "negative regulation of protein oligomerization" ; rdfs:subClassOf obo:GO_0031333, obo:GO_0032459, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051259 ] ) ] . obo:GO_0032461 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein oligomerization." ; oboInOwl:hasExactSynonym "up regulation of protein oligomerization", "up-regulation of protein oligomerization", "upregulation of protein oligomerization" ; oboInOwl:hasNarrowSynonym "activation of protein oligomerization", "stimulation of protein oligomerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "induction of protein oligomerization" ; oboInOwl:id "GO:0032461" ; a owl:Class ; rdfs:label "positive regulation of protein oligomerization" ; rdfs:subClassOf obo:GO_0031334, obo:GO_0032459, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051259 ] ) ] . obo:GO_0032465 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells." ; oboInOwl:hasAlternativeId "GO:0071775" ; oboInOwl:hasExactSynonym "regulation of cell cycle cytokinesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032465" ; a owl:Class ; rdfs:label "regulation of cytokinesis" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0051302, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000910 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000910 ] ) ] . obo:GO_0032466 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." ; oboInOwl:hasAlternativeId "GO:0071776" ; oboInOwl:hasExactSynonym "down regulation of cytokinesis", "down-regulation of cytokinesis", "downregulation of cytokinesis" ; oboInOwl:hasNarrowSynonym "inhibition of cytokinesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell cycle cytokinesis" ; oboInOwl:id "GO:0032466" ; a owl:Class ; rdfs:label "negative regulation of cytokinesis" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0032465, obo:GO_0051782, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000910 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000910 ] ) ] . obo:GO_0032467 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells." ; oboInOwl:hasAlternativeId "GO:0071777" ; oboInOwl:hasExactSynonym "up regulation of cytokinesis", "up-regulation of cytokinesis", "upregulation of cytokinesis" ; oboInOwl:hasNarrowSynonym "activation of cytokinesis", "stimulation of cytokinesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cell cycle cytokinesis" ; oboInOwl:id "GO:0032467" ; a owl:Class ; rdfs:label "positive regulation of cytokinesis" ; rdfs:subClassOf obo:GO_0032465, obo:GO_0051781, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000910 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000910 ] ) ] . obo:GO_0032501 obo:IAO_0000115 "Any biological process, occurring at the level of a multicellular organism, pertinent to its function." ; obo:RO_0002161 obo:NCBITaxon_2, obo:NCBITaxon_2157, obo:NCBITaxon_4896, obo:NCBITaxon_4932 ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T16:07:47Z" ; oboInOwl:hasAlternativeId "GO:0044707", "GO:0050874" ; oboInOwl:hasExactSynonym "organismal physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-multicellular organism process" ; oboInOwl:id "GO:0032501" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:label "multicellular organismal process" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0032502 obo:IAO_0000115 "A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-12-19T12:21:31Z" ; oboInOwl:hasAlternativeId "GO:0044767" ; oboInOwl:hasNarrowSynonym "development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism developmental process" ; oboInOwl:id "GO:0032502" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_pir ; a owl:Class ; rdfs:label "developmental process" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0032504 obo:IAO_0000115 "The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032504" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "multicellular organism reproduction" ; rdfs:subClassOf obo:GO_0000003, obo:GO_0032501 . obo:GO_0032507 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "maintenance of protein localization in cell" ; oboInOwl:id "GO:0032507" ; a owl:Class ; rdfs:label "maintenance of protein location in cell" ; rdfs:subClassOf obo:GO_0045185, obo:GO_0051651 . obo:GO_0032535 obo:IAO_0000115 "A process that modulates the size of a cellular component." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032535" ; a owl:Class ; rdfs:label "regulation of cellular component size" ; rdfs:subClassOf obo:GO_0016043, obo:GO_0090066 . obo:GO_0032543 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code." ; oboInOwl:hasExactSynonym "mitochondrial protein anabolism", "mitochondrial protein biosynthesis", "mitochondrial protein formation", "mitochondrial protein synthesis", "mitochondrial protein translation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032543" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "mitochondrial translation" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0006412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140053 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006412 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140053 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0032594 obo:IAO_0000115 "The directed movement of a protein from one location to another within a lipid bilayer." ; oboInOwl:hasExactSynonym "protein translocation within membrane" ; oboInOwl:hasNarrowSynonym "receptor translocation within membrane", "receptor transport within lipid bilayer" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032594" ; a owl:Class ; rdfs:label "protein transport within lipid bilayer" ; rdfs:subClassOf obo:GO_0006886, obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0015031 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0032774 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication." ; oboInOwl:hasAlternativeId "GO:0062103" ; oboInOwl:hasExactSynonym "RNA anabolism", "RNA biosynthesis", "RNA formation", "RNA synthesis" ; oboInOwl:hasNarrowSynonym "double-stranded RNA biosynthesis", "double-stranded RNA biosynthetic process", "dsRNA biosynthesis", "dsRNA biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032774" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study." ; rdfs:label "RNA biosynthetic process" ; rdfs:subClassOf obo:GO_0009059, obo:GO_0016070, obo:GO_0034654 . obo:GO_0032838 obo:IAO_0000115 "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032838" ; a owl:Class ; rdfs:label "plasma membrane bounded cell projection cytoplasm" ; rdfs:subClassOf obo:GO_0099568, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0120025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0120025 ] ) ] . obo:GO_0032839 obo:IAO_0000115 "All of the contents of a dendrite, excluding the surrounding plasma membrane." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI ; oboInOwl:hasExactSynonym "dendritic cytoplasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032839" ; a owl:Class ; rdfs:label "dendrite cytoplasm" ; rdfs:subClassOf obo:GO_0120111, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030425 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030425 ] ) ] . obo:GO_0032847 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell." ; oboInOwl:hasExactSynonym "regulation of cell pH reduction", "regulation of cellular acidification", "regulation of intracellular pH reduction", "regulation of reduction of cellular pH", "regulation of reduction of pH in cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of intracellular acidification" ; oboInOwl:id "GO:0032847" ; a owl:Class ; rdfs:label "regulation of cellular pH reduction" ; rdfs:subClassOf obo:GO_0050789, obo:GO_0051453, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051452 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051452 ] ) ] . obo:GO_0032848 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell." ; oboInOwl:hasExactSynonym "down regulation of cellular pH reduction", "down-regulation of cellular pH reduction", "downregulation of cellular pH reduction", "negative regulation of cell pH reduction", "negative regulation of cellular acidification", "negative regulation of intracellular pH reduction", "negative regulation of reduction of cellular pH", "negative regulation of reduction of pH in cell" ; oboInOwl:hasNarrowSynonym "inhibition of cellular pH reduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of intracellular acidification" ; oboInOwl:id "GO:0032848" ; a owl:Class ; rdfs:label "negative regulation of cellular pH reduction" ; rdfs:subClassOf obo:GO_0032847, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051452 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051452 ] ) ] . obo:GO_0032849 obo:IAO_0000115 "Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell." ; oboInOwl:hasExactSynonym "positive regulation of cell pH reduction", "positive regulation of cellular acidification", "positive regulation of intracellular pH reduction", "positive regulation of reduction of cellular pH", "positive regulation of reduction of pH in cell", "up regulation of cellular pH reduction", "up-regulation of cellular pH reduction", "upregulation of cellular pH reduction" ; oboInOwl:hasNarrowSynonym "activation of cellular pH reduction", "stimulation of cellular pH reduction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of intracellular acidification" ; oboInOwl:id "GO:0032849" ; a owl:Class ; rdfs:label "positive regulation of cellular pH reduction" ; rdfs:subClassOf obo:GO_0032847, obo:GO_0048518, obo:GO_0051452, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051452 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051452 ] ) ] . obo:GO_0032875 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of DNA endoreduplication." ; oboInOwl:hasExactSynonym "regulation of DNA endoreplication", "regulation of DNA re-duplication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032875" ; a owl:Class ; rdfs:label "regulation of DNA endoreduplication" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0090329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042023 ] ) ] . obo:GO_0032876 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication." ; oboInOwl:hasExactSynonym "down regulation of DNA endoreduplication", "down-regulation of DNA endoreduplication", "downregulation of DNA endoreduplication", "negative regulation of DNA endoreplication", "negative regulation of DNA re-duplication" ; oboInOwl:hasNarrowSynonym "inhibition of DNA endoreduplication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032876" ; a owl:Class ; rdfs:label "negative regulation of DNA endoreduplication" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0032875, obo:GO_2000104, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042023 ] ) ] . obo:GO_0032877 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of DNA endoreduplication." ; oboInOwl:hasExactSynonym "positive regulation of DNA endoreplication", "positive regulation of DNA re-duplication", "up regulation of DNA endoreduplication", "up-regulation of DNA endoreduplication", "upregulation of DNA endoreduplication" ; oboInOwl:hasNarrowSynonym "activation of DNA endoreduplication", "stimulation of DNA endoreduplication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032877" ; a owl:Class ; rdfs:label "positive regulation of DNA endoreduplication" ; rdfs:subClassOf obo:GO_0032875, obo:GO_0090068, obo:GO_2000105, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042023 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042023 ] ) ] . obo:GO_0032878 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032878" ; a owl:Class ; rdfs:label "regulation of establishment or maintenance of cell polarity" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007163 ] ) ] . obo:GO_0032879 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "regulation of localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032879" ; a owl:Class ; rdfs:label "regulation of localization" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051179 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051179 ] ) ] . obo:GO_0032880 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2015-01-20T14:32:14Z" ; oboInOwl:hasAlternativeId "GO:1903827" ; oboInOwl:hasExactSynonym "regulation of cellular protein localisation", "regulation of cellular protein localization", "regulation of protein localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032880" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "regulation of protein localization" ; rdfs:subClassOf obo:GO_0060341, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008104 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008104 ] ) ] . obo:GO_0032886 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032886" ; a owl:Class ; rdfs:label "regulation of microtubule-based process" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007017 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007017 ] ) ] . obo:GO_0032887 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032887" ; a owl:Class ; rdfs:label "regulation of spindle elongation" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0032886, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051231 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051231 ] ) ] . obo:GO_0032888 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032888" ; a owl:Class ; rdfs:label "regulation of mitotic spindle elongation" ; rdfs:subClassOf obo:GO_0032887, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033047 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000022 ] ) ] . obo:GO_0032939 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ; oboInOwl:hasExactSynonym "up regulation of translation in response to oxidative stress", "up-regulation of translation in response to oxidative stress", "upregulation of translation in response to oxidative stress" ; oboInOwl:hasNarrowSynonym "activation of translation in response to oxidative stress", "stimulation of translation in response to oxidative stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032939" ; a owl:Class ; rdfs:label "positive regulation of translation in response to oxidative stress" ; rdfs:subClassOf obo:GO_0032056, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034599 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0032940 obo:IAO_0000115 "The controlled release of a substance by a cell." ; oboInOwl:hasDbXref "Wikipedia:Secretion" ; oboInOwl:hasExactSynonym "cellular secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032940" ; a owl:Class ; rdfs:label "secretion by cell" ; rdfs:subClassOf obo:GO_0046903, obo:GO_0140352 . obo:GO_0032956 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ; oboInOwl:hasExactSynonym "regulation of actin cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of actin cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0032956" ; a owl:Class ; rdfs:label "regulation of actin cytoskeleton organization" ; rdfs:subClassOf obo:GO_0032970, obo:GO_0051493, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030036 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030036 ] ) ] . obo:GO_0032970 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032970" ; a owl:Class ; rdfs:label "regulation of actin filament-based process" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030029 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030029 ] ) ] . obo:GO_0032982 obo:IAO_0000115 "A supramolecular fiber containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "myosin thick filament", "thick filament" ; oboInOwl:id "GO:0032982" ; a owl:Class ; rdfs:label "myosin filament" ; rdfs:subClassOf obo:GO_0099512, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016459 ] . obo:GO_0032984 obo:IAO_0000115 "The disaggregation of a protein-containing macromolecular complex into its constituent components." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22580"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0034623", "GO:0043241", "GO:0043624" ; oboInOwl:hasExactSynonym "protein complex disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular macromolecule complex disassembly", "cellular protein complex disassembly", "macromolecule complex disassembly" ; oboInOwl:id "GO:0032984" ; a owl:Class ; rdfs:label "protein-containing complex disassembly" ; rdfs:subClassOf obo:GO_0022411, obo:GO_0043933 . obo:GO_0032989 obo:IAO_0000115 "The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25496"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/26249"^^xsd:anyURI ; oboInOwl:hasExactSynonym "cellular component morphogenesis", "cellular structure morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0032989" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular anatomical entity morphogenesis" ; rdfs:subClassOf obo:GO_0009653 . obo:GO_0032991 obo:IAO_0000115 "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together." ; oboInOwl:hasAlternativeId "GO:0043234" ; oboInOwl:hasExactSynonym "macromolecular complex", "macromolecule complex", "protein containing complex" ; oboInOwl:hasNarrowSynonym "protein complex", "protein-protein complex" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0032991" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir ; a owl:Class ; rdfs:comment "A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole." ; rdfs:label "protein-containing complex" ; rdfs:subClassOf obo:GO_0005575 . obo:GO_0033036 obo:IAO_0000115 "Any process in which a macromolecule is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "macromolecule localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033036" ; oboInOwl:inSubset go:goslim_flybase_ribbon ; a owl:Class ; rdfs:label "macromolecule localization" ; rdfs:subClassOf obo:GO_0051179 . obo:GO_0033043 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle." ; oboInOwl:hasExactSynonym "regulation of organelle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of organelle organization and biogenesis" ; oboInOwl:id "GO:0033043" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of organelle organization" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006996 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006996 ] ) ] . obo:GO_0033044 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome." ; oboInOwl:hasExactSynonym "regulation of chromosome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of chromosome organization and biogenesis" ; oboInOwl:id "GO:0033044" ; a owl:Class ; rdfs:label "regulation of chromosome organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051276 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051276 ] ) ] . obo:GO_0033045 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of sister chromatid segregation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033045" ; a owl:Class ; rdfs:label "regulation of sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033044, obo:GO_0051983, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000819 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000819 ] ) ] . obo:GO_0033046 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033046" ; a owl:Class ; rdfs:label "negative regulation of sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033045, obo:GO_0051985, obo:GO_2001251, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000819 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000819 ] ) ] . obo:GO_0033047 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033047" ; a owl:Class ; rdfs:label "regulation of mitotic sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033045, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000070 ] ) ] . obo:GO_0033048 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033048" ; a owl:Class ; rdfs:label "negative regulation of mitotic sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033046, obo:GO_0033047, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000070 ] ) ] . obo:GO_0033058 obo:IAO_0000115 "Self-propelled movement of a cell or organism from one location to another along an axis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033058" ; a owl:Class ; rdfs:label "directional locomotion" ; rdfs:subClassOf obo:GO_0040011 . obo:GO_0033059 obo:IAO_0000115 "The deposition or aggregation of coloring matter in a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033059" ; a owl:Class ; rdfs:label "cellular pigmentation" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0043473 . obo:GO_0033119 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033119" ; a owl:Class ; rdfs:label "negative regulation of RNA splicing" ; rdfs:subClassOf obo:GO_0010629, obo:GO_0043484, obo:GO_0051253, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008380 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008380 ] ) ] . obo:GO_0033120 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of RNA splicing." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033120" ; a owl:Class ; rdfs:label "positive regulation of RNA splicing" ; rdfs:subClassOf obo:GO_0010628, obo:GO_0043484, obo:GO_0051254, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008380 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008380 ] ) ] . obo:GO_0033157 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033157" ; a owl:Class ; rdfs:label "regulation of intracellular protein transport" ; rdfs:subClassOf obo:GO_0032386, obo:GO_0051223, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006886 ] ) ] . obo:GO_0033206 obo:IAO_0000115 "A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells." ; oboInOwl:hasExactSynonym "cytokinesis after meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033206" ; a owl:Class ; rdfs:label "meiotic cytokinesis" ; rdfs:subClassOf obo:GO_0061640, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0061640 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0033238 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines." ; oboInOwl:hasExactSynonym "regulation of amine metabolism", "regulation of cellular amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033238" ; a owl:Class ; rdfs:label "regulation of amine metabolic process" ; rdfs:subClassOf obo:GO_0051171, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009308 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009308 ] ) ] . obo:GO_0033239 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines." ; oboInOwl:hasExactSynonym "negative regulation of amine metabolism", "negative regulation of cellular amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033239" ; a owl:Class ; rdfs:label "negative regulation of amine metabolic process" ; rdfs:subClassOf obo:GO_0033238, obo:GO_0051172, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009308 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009308 ] ) ] . obo:GO_0033240 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines." ; oboInOwl:hasExactSynonym "positive regulation of amine metabolism", "positive regulation of cellular amine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033240" ; a owl:Class ; rdfs:label "positive regulation of amine metabolic process" ; rdfs:subClassOf obo:GO_0033238, obo:GO_0051173, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009308 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009308 ] ) ] . obo:GO_0033241 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ; oboInOwl:hasExactSynonym "regulation of amine breakdown", "regulation of amine catabolism", "regulation of amine degradation", "regulation of cellular amine catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033241" ; a owl:Class ; rdfs:label "regulation of amine catabolic process" ; rdfs:subClassOf obo:GO_0009894, obo:GO_0033238, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009310 ] ) ] . obo:GO_0033242 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ; oboInOwl:hasExactSynonym "negative regulation of amine breakdown", "negative regulation of amine catabolism", "negative regulation of amine degradation", "negative regulation of cellular amine catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033242" ; a owl:Class ; rdfs:label "negative regulation of amine catabolic process" ; rdfs:subClassOf obo:GO_0009895, obo:GO_0033239, obo:GO_0033241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009310 ] ) ] . obo:GO_0033243 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines." ; oboInOwl:hasExactSynonym "positive regulation of amine breakdown", "positive regulation of amine catabolism", "positive regulation of amine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033243" ; a owl:Class ; rdfs:label "positive regulation of amine catabolic process" ; rdfs:subClassOf obo:GO_0009896, obo:GO_0033240, obo:GO_0033241, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009310 ] ) ] . obo:GO_0033260 obo:IAO_0000115 "The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." ; oboInOwl:hasExactSynonym "DNA replication involved in S phase", "DNA replication involved in S-phase", "nuclear cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA replication during S phase" ; oboInOwl:id "GO:0033260" ; a owl:Class ; rdfs:label "nuclear DNA replication" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0044786, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006260 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007049 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0033262 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle." ; oboInOwl:hasExactSynonym "regulation of DNA replication involved in S phase", "regulation of DNA replication involved in S-phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of DNA replication during S phase" ; oboInOwl:id "GO:0033262" ; a owl:Class ; rdfs:label "regulation of nuclear cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0090329, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033260 ] ) ] . obo:GO_0033313 obo:IAO_0000115 "A signaling process that contributes to a meiotic cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072411" ; oboInOwl:hasExactSynonym "meiotic cell cycle checkpoint", "signal transduction involved in meiotic cell cycle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033313" ; a owl:Class ; rdfs:label "meiotic cell cycle checkpoint signaling" ; rdfs:subClassOf obo:GO_0000075, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000075 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0033316 obo:IAO_0000115 "A signal transduction process that contributes to a meiotic spindle assembly checkpoint, that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0072465" ; oboInOwl:hasExactSynonym "meiotic spindle assembly checkpoint", "signal transduction involved in meiotic spindle assembly checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033316" ; a owl:Class ; rdfs:label "meiotic spindle assembly checkpoint signaling" ; rdfs:subClassOf obo:GO_0044779, obo:GO_0071173 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071173 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0033363 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion." ; oboInOwl:hasExactSynonym "secretory granule organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "secretory granule organization and biogenesis" ; oboInOwl:id "GO:0033363" ; a owl:Class ; rdfs:label "secretory granule organization" ; rdfs:subClassOf obo:GO_0016050, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0010256 ] . obo:GO_0033365 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within an organelle." ; oboInOwl:hasExactSynonym "protein localisation to organelle", "protein localization in organelle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033365" ; a owl:Class ; rdfs:label "protein localization to organelle" ; rdfs:subClassOf obo:GO_0008104 . obo:GO_0033554 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0033554" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to stress" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0051716 . obo:GO_0034059 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%." ; oboInOwl:hasExactSynonym "response to anoxic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034059" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'response to hypoxia ; GO:0001666'." ; rdfs:label "response to anoxia" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0036293 . obo:GO_0034242 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034242" ; a owl:Class ; rdfs:label "negative regulation of syncytium formation by plasma membrane fusion" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0051129, obo:GO_0060142, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000768 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000768 ] ) ] . obo:GO_0034248 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides." ; oboInOwl:hasExactSynonym "regulation of amide metabolism", "regulation of cellular amide metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034248" ; a owl:Class ; rdfs:label "regulation of amide metabolic process" ; rdfs:subClassOf obo:GO_0051171, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043603 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043603 ] ) ] . obo:GO_0034249 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides." ; oboInOwl:hasExactSynonym "negative regulation of amide metabolism", "negative regulation of cellular amide metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034249" ; a owl:Class ; rdfs:label "negative regulation of amide metabolic process" ; rdfs:subClassOf obo:GO_0034248, obo:GO_0051172, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043603 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043603 ] ) ] . obo:GO_0034250 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides." ; oboInOwl:hasExactSynonym "positive regulation of amide metabolism", "positive regulation of cellular amide metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034250" ; a owl:Class ; rdfs:label "positive regulation of amide metabolic process" ; rdfs:subClassOf obo:GO_0034248, obo:GO_0051173, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043603 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043603 ] ) ] . obo:GO_0034263 obo:IAO_0000115 "The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy." ; oboInOwl:hasExactSynonym "autophagy in response to ER stress", "autophagy in response to endoplasmic reticulum overload" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034263" ; a owl:Class ; rdfs:label "positive regulation of autophagy in response to ER overload" ; rdfs:subClassOf obo:GO_0006983, obo:GO_0010508 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006983 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006914 ] ) ] . obo:GO_0034329 obo:IAO_0000115 "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034329" ; a owl:Class ; rdfs:label "cell junction assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0034330 . obo:GO_0034330 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix." ; oboInOwl:hasExactSynonym "cell junction assembly and maintenance", "cell junction organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell junction biogenesis" ; oboInOwl:id "GO:0034330" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic ; a owl:Class ; rdfs:label "cell junction organization" ; rdfs:subClassOf obo:GO_0016043 . obo:GO_0034504 obo:IAO_0000115 "A process in which a protein transports or maintains the localization of another protein to the nucleus." ; oboInOwl:creation_date "2012-11-07T15:45:54Z" ; oboInOwl:hasAlternativeId "GO:0044744" ; oboInOwl:hasExactSynonym "protein localisation to nucleus", "protein localization in cell nucleus", "protein localization in nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein targeting to nucleus" ; oboInOwl:id "GO:0034504" ; a owl:Class ; rdfs:label "protein localization to nucleus" ; rdfs:subClassOf obo:GO_0033365 . obo:GO_0034599 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ; oboInOwl:hasNarrowSynonym "adaptive response to oxidative stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034599" ; a owl:Class ; rdfs:label "cellular response to oxidative stress" ; rdfs:subClassOf obo:GO_0006979, obo:GO_0062197 . obo:GO_0034606 obo:IAO_0000115 "The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034606" ; a owl:Class ; rdfs:label "response to hermaphrodite contact" ; rdfs:subClassOf obo:GO_0060179 . obo:GO_0034608 obo:IAO_0000115 "Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034608" ; a owl:Class ; rdfs:label "vulval location" ; rdfs:subClassOf obo:GO_0060179 . obo:GO_0034609 obo:IAO_0000115 "Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034609" ; a owl:Class ; rdfs:label "spicule insertion" ; rdfs:subClassOf obo:GO_0060179 . obo:GO_0034613 obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:GO_0008104 ; a owl:Class ; owl:deprecated true . obo:GO_0034620 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "heat shock protein activity" ; oboInOwl:id "GO:0034620" ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'unfolded protein response ; GO:0030968', which refers to the signaling pathways that respond to the presence of unfolded proteins in the ER." ; rdfs:label "cellular response to unfolded protein" ; rdfs:subClassOf obo:GO_0006986, obo:GO_0035967 . obo:GO_0034641 obo:IAO_0000115 "The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells." ; oboInOwl:hasExactSynonym "cellular nitrogen compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034641" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "cellular nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0006807, obo:GO_0044237 . obo:GO_0034644 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers." ; oboInOwl:hasExactSynonym "cellular response to UV light stimulus", "cellular response to UV radiation stimulus", "cellular response to ultraviolet light stimulus", "cellular response to ultraviolet radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034644" ; a owl:Class ; rdfs:label "cellular response to UV" ; rdfs:subClassOf obo:GO_0009411, obo:GO_0071482 . obo:GO_0034654 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "nucleobase, nucleoside, nucleotide and nucleic acid anabolism", "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis", "nucleobase, nucleoside, nucleotide and nucleic acid formation" ; oboInOwl:hasNarrowSynonym "nucleobase, nucleoside, nucleotide and nucleic acid synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034654" ; a owl:Class ; rdfs:label "nucleobase-containing compound biosynthetic process" ; rdfs:subClassOf obo:GO_0006139, obo:GO_0018130, obo:GO_0019438, obo:GO_0044271, obo:GO_1901362 . obo:GO_0034655 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "nucleobase, nucleoside, nucleotide and nucleic acid breakdown", "nucleobase, nucleoside, nucleotide and nucleic acid catabolism", "nucleobase, nucleoside, nucleotide and nucleic acid degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process" ; oboInOwl:id "GO:0034655" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "nucleobase-containing compound catabolic process" ; rdfs:subClassOf obo:GO_0006139, obo:GO_0019439, obo:GO_0044270, obo:GO_0046700, obo:GO_1901361 . obo:GO_0034976 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." ; oboInOwl:hasExactSynonym "ER stress response", "cellular response to endoplasmic reticulum stress", "response to ER stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0034976" ; a owl:Class ; rdfs:label "response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0033554 . obo:GO_0035046 obo:IAO_0000115 "The directed movement of the male and female pronuclei towards each other prior to their fusion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035046" ; a owl:Class ; rdfs:label "pronuclear migration" ; rdfs:subClassOf obo:GO_0007097, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007338 ] . obo:GO_0035047 obo:IAO_0000115 "The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035047" ; a owl:Class ; rdfs:label "centrosomal and pronuclear rotation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007338 ] . obo:GO_0035176 obo:IAO_0000115 "Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group." ; oboInOwl:hasDbXref "Wikipedia:Social_behavior" ; oboInOwl:hasExactSynonym "social behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cooperative behavior" ; oboInOwl:id "GO:0035176" ; a owl:Class ; rdfs:comment "Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior." ; rdfs:label "social behavior" ; rdfs:subClassOf obo:GO_0007610, obo:GO_0051703 . obo:GO_0035177 obo:IAO_0000115 "The movement of a larva through a feeding substrate whilst feeding on food." ; oboInOwl:hasExactSynonym "larval foraging behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035177" ; a owl:Class ; rdfs:label "larval foraging behavior" ; rdfs:subClassOf obo:GO_0030537, obo:GO_0060756 . obo:GO_0035188 obo:IAO_0000115 "The emergence of an immature organism from a protective structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035188" ; a owl:Class ; rdfs:label "hatching" ; rdfs:subClassOf obo:GO_0071684, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0035295 obo:IAO_0000115 "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035295" ; a owl:Class ; rdfs:label "tube development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0035437 obo:IAO_0000115 "Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-04-09T10:39:49Z" ; oboInOwl:hasExactSynonym "maintenance of protein localisation in endoplasmic reticulum", "maintenance of protein localization in ER", "maintenance of protein location in ER", "maintenance of protein location in endoplasmic reticulum", "protein-ER retention", "protein-endoplasmic reticulum retention", "retention of protein in ER", "retention of protein in endoplasmic reticulum" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035437" ; a owl:Class ; rdfs:label "maintenance of protein localization in endoplasmic reticulum" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070972 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005783 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005783 ] ) ] . obo:GO_0035556 obo:IAO_0000115 "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-05-14T01:14:37Z" ; oboInOwl:hasAlternativeId "GO:0007242", "GO:0007243", "GO:0023013", "GO:0023034" ; oboInOwl:hasExactSynonym "intracellular signaling chain" ; oboInOwl:hasNarrowSynonym "intracellular protein kinase cascade", "intracellular signal transduction pathway", "protein kinase cascade", "signal transmission via intracellular cascade" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intracellular signaling cascade", "intracellular signaling pathway", "signal transduction via intracellular signaling cascade" ; oboInOwl:id "GO:0035556" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "intracellular signal transduction" ; rdfs:subClassOf obo:GO_0007165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007165 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0035592 obo:IAO_0000115 "The directed movement of a protein to a specific location within the extracellular region." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-11-09T10:25:08Z" ; oboInOwl:hasExactSynonym "establishment of protein localisation in extracellular region", "establishment of protein localization in extracellular region" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035592" ; a owl:Class ; rdfs:label "establishment of protein localization to extracellular region" ; rdfs:subClassOf obo:GO_0045184, obo:GO_0071692 . obo:GO_0035694 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-02-28T11:06:40Z" ; oboInOwl:hasExactSynonym "catabolism of mitochondrial protein", "degradation of damaged mitochondrial protein" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0035694" ; a owl:Class ; rdfs:label "mitochondrial protein catabolic process" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0030163, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007005 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030163 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0035770 obo:IAO_0000115 "A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-01T10:50:47Z" ; oboInOwl:hasExactSynonym "RNP granule", "mRNP granule" ; oboInOwl:hasNarrowSynonym "RNA granule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0035770" ; a owl:Class ; rdfs:label "ribonucleoprotein granule" ; rdfs:subClassOf obo:GO_0043232, obo:GO_0099080 . obo:GO_0035825 obo:IAO_0000115 "A DNA recombination process that results in the exchange of an equal amount of genetic material between highly homologous DNA molecules." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/18777"^^xsd:anyURI ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-05-04T01:23:31Z" ; oboInOwl:hasDbXref "Wikipedia:Chromosomal_crossover" ; oboInOwl:hasExactSynonym "interchromosomal DNA recombination", "interstrand DNA recombination" ; oboInOwl:hasNarrowSynonym "reciprocal DNA recombination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosomal crossover" ; oboInOwl:id "GO:0035825" ; a owl:Class ; rdfs:label "homologous recombination" ; rdfs:subClassOf obo:GO_0006310 . obo:GO_0035882 obo:IAO_0000115 "The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-06T11:36:35Z" ; oboInOwl:hasExactSynonym "DMP", "defecation cycle", "defecation motor program" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "defecation behavior" ; oboInOwl:id "GO:0035882" ; a owl:Class ; rdfs:label "defecation rhythm" ; rdfs:subClassOf obo:GO_0007624, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030421 ] . obo:GO_0035915 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-07-01T11:45:01Z" ; oboInOwl:hasExactSynonym "pore complex assembly in other organism", "pore complex biogenesis in other organism", "pore formation in membrane of other organism", "pore formation in other organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pore-forming toxin activity" ; oboInOwl:id "GO:0035915" ; a owl:Class ; rdfs:label "pore formation in membrane of another organism" ; rdfs:subClassOf obo:GO_0051673 . obo:GO_0035966 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-08-03T11:43:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "response to misfolded or unfolded protein" ; oboInOwl:id "GO:0035966" ; a owl:Class ; rdfs:label "response to topologically incorrect protein" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0010033 . obo:GO_0035967 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-08-03T11:44:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular response to misfolded or unfolded protein" ; oboInOwl:id "GO:0035967" ; a owl:Class ; rdfs:label "cellular response to topologically incorrect protein" ; rdfs:subClassOf obo:GO_0033554, obo:GO_0035966, obo:GO_0071310 . obo:GO_0036194 obo:IAO_0000115 "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-04-20T10:20:47Z" ; oboInOwl:hasExactSynonym "myocyte projection" ; oboInOwl:hasNarrowSynonym "muscle arm", "myopodia" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0036194" ; a owl:Class ; rdfs:label "muscle cell projection" ; rdfs:subClassOf obo:GO_0120025 . obo:GO_0036211 obo:IAO_0000115 "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-04-26T01:47:12Z" ; oboInOwl:hasAlternativeId "GO:0006464" ; oboInOwl:hasExactSynonym "cellular protein modification process", "process resulting in protein modification", "protein modification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036211" ; oboInOwl:inSubset go:goslim_candida, go:goslim_chembl, go:goslim_pir, go:goslim_plant, go:prokaryote_subset ; a owl:Class ; rdfs:label "protein modification process" ; rdfs:subClassOf obo:GO_0019538, obo:GO_0043412 . obo:GO_0036276 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-07-09T02:12:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036276" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to antidepressant" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0036293 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-07-20T01:05:46Z" ; oboInOwl:hasExactSynonym "response to lowered oxygen levels" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036293" ; a owl:Class ; rdfs:comment "This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'." ; rdfs:label "response to decreased oxygen levels" ; rdfs:subClassOf obo:GO_0070482 . obo:GO_0036379 obo:IAO_0000115 "Any of the smallest contractile units of a myofibril (striated muscle fiber)." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2013-05-22T14:39:06Z" ; oboInOwl:hasExactSynonym "striated muscle filament" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0036379" ; a owl:Class ; rdfs:label "myofilament" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030016 ] . obo:GO_0036464 obo:IAO_0000115 "A ribonucleoprotein granule located in the cytoplasm." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-06-18T09:44:44Z" ; oboInOwl:hasNarrowSynonym "Staufen granule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0036464" ; a owl:Class ; rdfs:label "cytoplasmic ribonucleoprotein granule" ; rdfs:subClassOf obo:GO_0035770, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0035770 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0036465 obo:IAO_0000115 "The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-06-26T11:03:08Z" ; oboInOwl:hasNarrowSynonym "kiss-and-run synaptic vesicle recycling", "kiss-and-stay synaptic vesicle recycling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036465" ; a owl:Class ; rdfs:label "synaptic vesicle recycling" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0006810, obo:GO_0051649, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099504 ] . obo:GO_0036477 obo:IAO_0000115 "The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-07-24T10:06:19Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0036477" ; a owl:Class ; rdfs:label "somatodendritic compartment" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0036490 obo:IAO_0000115 "Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2015-02-05T09:50:11Z" ; oboInOwl:hasExactSynonym "regulation of translation in response to ER stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036490" ; a owl:Class ; rdfs:label "regulation of translation in response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0043555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034976 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034976 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0036493 obo:IAO_0000115 "Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2015-02-05T10:09:51Z" ; oboInOwl:hasExactSynonym "positive regulation of translation in response to ER stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0036493" ; a owl:Class ; rdfs:label "positive regulation of translation in response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0032056, obo:GO_0036490 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034976 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0038024 obo:IAO_0000115 "Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-08-01T02:50:45Z" ; oboInOwl:hasBroadSynonym "receptor activity", "transport receptor activity" ; oboInOwl:hasDbXref "Reactome:R-HSA-3000103", "Reactome:R-HSA-3000112", "Reactome:R-HSA-3000122", "Reactome:R-HSA-3000137", "Reactome:R-HSA-350168", "Reactome:R-HSA-9759202", "Reactome:R-HSA-9759209" ; oboInOwl:hasNarrowSynonym "endocytic receptor activity", "receptor activity involved in receptor-mediated endocytosis" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0038024" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic ; a owl:Class ; rdfs:comment "Notes: (1) this term and its child terms are intended for receptors that bind to and internalize molecules by receptor-mediated endocytosis. For receptors that are coupled to a signal transduction pathway, consider instead the term 'signaling receptor activity ; GO:0038023' and its children. (2) Cargo receptors transport substances by vesicular transport, not by transmembrane transport. For transmembrane transporters, consider instead the term 'transmembrane transporter activity ; GO:0022857." ; rdfs:label "cargo receptor activity" ; rdfs:subClassOf obo:GO_0003674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006897 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0060090 ] . obo:GO_0040001 obo:IAO_0000115 "The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs." ; oboInOwl:hasAlternativeId "GO:0018986", "GO:0030605", "GO:0030606", "GO:0030608", "GO:0030610" ; oboInOwl:hasExactSynonym "establishment of mitotic spindle localisation", "mitotic spindle positioning", "mitotic spindle positioning or orientation", "spindle positioning involved in mitotic cell cycle" ; oboInOwl:hasNarrowSynonym "mitotic spindle positioning and orientation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "spindle positioning during mitosis" ; oboInOwl:id "GO:0040001" ; a owl:Class ; rdfs:label "establishment of mitotic spindle localization" ; rdfs:subClassOf obo:GO_0051293, obo:GO_1902850 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051293 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0040002 obo:IAO_0000115 "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans." ; oboInOwl:hasExactSynonym "collagen and cuticulin-based cuticle anabolism", "collagen and cuticulin-based cuticle biosynthetic process", "collagen and cuticulin-based cuticle formation", "collagen and cuticulin-based cuticle synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040002" ; a owl:Class ; rdfs:label "collagen and cuticulin-based cuticle development" ; rdfs:subClassOf obo:GO_0042335 . obo:GO_0040004 obo:IAO_0000115 "Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans." ; oboInOwl:hasBroadSynonym "cuticular attachment to epithelium" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040004" ; a owl:Class ; rdfs:label "collagen and cuticulin-based cuticle attachment to epithelium" ; rdfs:subClassOf obo:GO_0022404, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0018996 ] . obo:GO_0040007 obo:IAO_0000115 "The increase in size or mass of an entire organism, a part of an organism or a cell." ; oboInOwl:hasAlternativeId "GO:0048590" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "growth pattern", "non-developmental growth" ; oboInOwl:id "GO:0040007" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_chembl, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:comment "See also the biological process term 'cell growth ; GO:0016049'." ; rdfs:label "growth" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0040008 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040008" ; a owl:Class ; rdfs:label "regulation of growth" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040007 ] ) ] . obo:GO_0040011 obo:IAO_0000115 "Self-propelled movement of a cell or organism from one location to another." ; obo:RO_0002161 obo:NCBITaxon_451864 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040011" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "locomotion" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0044848 . obo:GO_0040012 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of locomotion of a cell or organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040012" ; a owl:Class ; rdfs:label "regulation of locomotion" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040011 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040011 ] ) ] . obo:GO_0040013 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism." ; oboInOwl:hasExactSynonym "down regulation of locomotion", "down-regulation of locomotion", "downregulation of locomotion" ; oboInOwl:hasNarrowSynonym "inhibition of locomotion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040013" ; a owl:Class ; rdfs:label "negative regulation of locomotion" ; rdfs:subClassOf obo:GO_0040012, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040011 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040011 ] ) ] . obo:GO_0040017 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism." ; oboInOwl:hasExactSynonym "up regulation of locomotion", "up-regulation of locomotion", "upregulation of locomotion" ; oboInOwl:hasNarrowSynonym "activation of locomotion", "stimulation of locomotion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040017" ; a owl:Class ; rdfs:label "positive regulation of locomotion" ; rdfs:subClassOf obo:GO_0040012, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040011 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040011 ] ) ] . obo:GO_0040019 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of embryonic development." ; oboInOwl:hasExactSynonym "up regulation of embryonic development", "up-regulation of embryonic development", "upregulation of embryonic development" ; oboInOwl:hasNarrowSynonym "activation of embryonic development", "stimulation of embryonic development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040019" ; a owl:Class ; rdfs:label "positive regulation of embryonic development" ; rdfs:subClassOf obo:GO_0045995, obo:GO_0051094, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009790 ] ) ] . obo:GO_0040020 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes." ; oboInOwl:hasBroadSynonym "regulation of meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040020" ; a owl:Class ; rdfs:label "regulation of meiotic nuclear division" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0051445, obo:GO_0051783, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0040021 obo:IAO_0000115 "The determination of sex and sexual phenotype in the germ line of a hermaphrodite." ; oboInOwl:hasAlternativeId "GO:0042005" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040021" ; a owl:Class ; rdfs:label "hermaphrodite germ-line sex determination" ; rdfs:subClassOf obo:GO_0018992 . obo:GO_0040022 obo:IAO_0000115 "The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040022" ; a owl:Class ; rdfs:label "feminization of hermaphroditic germ-line" ; rdfs:subClassOf obo:GO_0040021 . obo:GO_0040024 obo:IAO_0000115 "The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040024" ; a owl:Class ; rdfs:label "dauer larval development" ; rdfs:subClassOf obo:GO_0002119 . obo:GO_0040025 obo:IAO_0000115 "The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040025" ; a owl:Class ; rdfs:label "vulval development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002119 ] . obo:GO_0040026 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of vulval development", "stimulation of vulval development", "up regulation of vulval development", "up-regulation of vulval development", "upregulation of vulval development" ; oboInOwl:id "GO:0040026" ; a owl:Class ; rdfs:label "positive regulation of vulval development" ; rdfs:subClassOf obo:GO_0040028, obo:GO_0051094, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040025 ] ) ] . obo:GO_0040027 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ; oboInOwl:hasExactSynonym "down regulation of vulval development", "down-regulation of vulval development", "downregulation of vulval development" ; oboInOwl:hasNarrowSynonym "inhibition of vulval development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040027" ; a owl:Class ; rdfs:label "negative regulation of vulval development" ; rdfs:subClassOf obo:GO_0040028, obo:GO_0061064, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040025 ] ) ] . obo:GO_0040028 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040028" ; a owl:Class ; rdfs:label "regulation of vulval development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040025 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040025 ] ) ] . obo:GO_0040029 obo:IAO_0000115 "A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22201"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/24794"^^xsd:anyURI ; oboInOwl:hasExactSynonym "regulation of gene expression, epigenetic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040029" ; oboInOwl:inSubset go:goslim_plant ; a owl:Class ; rdfs:label "epigenetic regulation of gene expression" ; rdfs:subClassOf obo:GO_0006338, obo:GO_0010468 . obo:GO_0040034 obo:IAO_0000115 "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached." ; oboInOwl:hasExactSynonym "heterochronic regulation of development", "temporal regulation of development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "developmental timing" ; oboInOwl:id "GO:0040034" ; a owl:Class ; rdfs:label "regulation of development, heterochronic" ; rdfs:subClassOf obo:GO_0050793 . obo:GO_0040038 obo:IAO_0000115 "The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040038" ; a owl:Class ; rdfs:label "polar body extrusion after meiotic divisions" ; rdfs:subClassOf obo:GO_0022412, obo:GO_0033206, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] . obo:GO_0040040 obo:IAO_0000115 "Behavior that is dependent upon the sensation of temperature." ; oboInOwl:hasExactSynonym "behavioral response to temperature stimulus", "behavioural response to temperature stimulus", "thermosensory behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0040040" ; a owl:Class ; rdfs:label "thermosensory behavior" ; rdfs:subClassOf obo:GO_0007610, obo:GO_0009266 . obo:GO_0042023 obo:IAO_0000115 "Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes." ; obo:RO_0002161 obo:NCBITaxon_4896 ; oboInOwl:hasExactSynonym "DNA endoreplication", "DNA re-duplication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042023" ; a owl:Class ; rdfs:comment "Note that this term is only to be used in situations were this process occurs normally. Not to be used to describe mutant or diseased states." ; rdfs:label "DNA endoreduplication" ; rdfs:subClassOf obo:GO_0044786, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0006270 ] . obo:GO_0042048 obo:IAO_0000115 "The behavior of an organism in response to an odor." ; oboInOwl:hasExactSynonym "behavioral response to scent", "behavioral response to smell", "behavioural response to odour", "behavioural response to scent", "behavioural response to smell", "olfactory behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042048" ; a owl:Class ; rdfs:label "olfactory behavior" ; rdfs:subClassOf obo:GO_0007635 . obo:GO_0042053 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ; oboInOwl:hasExactSynonym "regulation of dopamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042053" ; a owl:Class ; rdfs:label "regulation of dopamine metabolic process" ; rdfs:subClassOf obo:GO_0042069, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042417 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042417 ] ) ] . obo:GO_0042069 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines." ; oboInOwl:hasExactSynonym "regulation of catecholamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042069" ; a owl:Class ; rdfs:label "regulation of catecholamine metabolic process" ; rdfs:subClassOf obo:GO_0031323, obo:GO_0033238, obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006584 ] ) ] . obo:GO_0042073 obo:IAO_0000115 "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins." ; obo:RO_0002161 obo:NCBITaxon_3176, obo:NCBITaxon_3312, obo:NCBITaxon_3378, obo:NCBITaxon_3398, obo:NCBITaxon_4890, obo:NCBITaxon_5782 ; oboInOwl:hasAlternativeId "GO:0035734" ; oboInOwl:hasDbXref "Wikipedia:Intraflagellar_transport" ; oboInOwl:hasExactSynonym "intraflagellar transport", "intraflagellar transport involved in cilium organization", "intraflagellar transport involved in microtubule-based flagellum organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "IFT" ; oboInOwl:id "GO:0042073" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "intraciliary transport" ; rdfs:subClassOf obo:GO_0010970, obo:GO_0031503, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044782 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005929 ] . obo:GO_0042074 obo:IAO_0000115 "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042074" ; a owl:Class ; rdfs:label "cell migration involved in gastrulation" ; rdfs:subClassOf obo:GO_0001667, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016477 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007369 ] ) ] . obo:GO_0042127 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell proliferation." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cell proliferation" ; oboInOwl:id "GO:0042127" ; a owl:Class ; rdfs:label "regulation of cell population proliferation" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008283 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008283 ] ) ] . obo:GO_0042133 obo:IAO_0000115 "OBSOLETE. The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25736"^^xsd:anyURI ; oboInOwl:hasExactSynonym "neurotransmitter metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042133" ; a owl:Class ; rdfs:comment "The reason for obsoletion is that 'neurotransmitter' is unnecessary grouping in the metabolism branch of the ontology, and it creates true path violations." ; rdfs:label "obsolete neurotransmitter metabolic process" ; owl:deprecated true . obo:GO_0042176 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-08-21T15:05:45Z" ; oboInOwl:hasAlternativeId "GO:1903362", "GO:2000598" ; oboInOwl:hasExactSynonym "regulation of cellular protein breakdown", "regulation of cellular protein catabolic process", "regulation of cellular protein catabolism", "regulation of cellular protein degradation", "regulation of protein breakdown", "regulation of protein catabolism", "regulation of protein degradation" ; oboInOwl:hasNarrowSynonym "regulation of cyclin breakdown", "regulation of cyclin catabolic process", "regulation of cyclin catabolism", "regulation of cyclin degradation", "regulation of degradation of cyclin" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042176" ; a owl:Class ; rdfs:label "regulation of protein catabolic process" ; rdfs:subClassOf obo:GO_0009894, obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030163 ] ) ] . obo:GO_0042177 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:1903363", "GO:2000599" ; oboInOwl:hasExactSynonym "down regulation of cellular protein breakdown", "down regulation of cellular protein catabolic process", "down regulation of cellular protein catabolism", "down regulation of cellular protein degradation", "down regulation of protein catabolic process", "down-regulation of cellular protein breakdown", "down-regulation of cellular protein catabolic process", "down-regulation of cellular protein catabolism", "down-regulation of cellular protein degradation", "down-regulation of protein catabolic process", "downregulation of cellular protein breakdown", "downregulation of cellular protein catabolic process", "downregulation of cellular protein catabolism", "downregulation of cellular protein degradation", "downregulation of protein catabolic process", "negative regulation of cellular protein breakdown", "negative regulation of cellular protein catabolic process", "negative regulation of cellular protein catabolism", "negative regulation of cellular protein degradation", "negative regulation of protein breakdown", "negative regulation of protein catabolism", "negative regulation of protein degradation" ; oboInOwl:hasNarrowSynonym "inhibition of cellular protein breakdown", "inhibition of cellular protein catabolic process", "inhibition of cellular protein catabolism", "inhibition of cellular protein degradation", "inhibition of protein catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042177" ; a owl:Class ; rdfs:label "negative regulation of protein catabolic process" ; rdfs:subClassOf obo:GO_0009895, obo:GO_0042176, obo:GO_0051248, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030163 ] ) ] . obo:GO_0042221 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ; oboInOwl:hasExactSynonym "response to chemical stimulus", "response to chemical substance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042221" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_candida, go:goslim_drosophila, go:goslim_metagenomics, go:goslim_plant, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to chemical" ; rdfs:subClassOf obo:GO_0050896 . obo:GO_0042303 obo:IAO_0000115 "The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042303" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:label "molting cycle" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0042325 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042325" ; a owl:Class ; rdfs:label "regulation of phosphorylation" ; rdfs:subClassOf obo:GO_0019220, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016310 ] ) ] . obo:GO_0042326 obo:IAO_0000115 "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule." ; oboInOwl:hasExactSynonym "down regulation of phosphorylation", "down-regulation of phosphorylation", "downregulation of phosphorylation" ; oboInOwl:hasNarrowSynonym "inhibition of phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042326" ; a owl:Class ; rdfs:label "negative regulation of phosphorylation" ; rdfs:subClassOf obo:GO_0042325, obo:GO_0045936, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016310 ] ) ] . obo:GO_0042327 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule." ; oboInOwl:hasExactSynonym "up regulation of phosphorylation", "up-regulation of phosphorylation", "upregulation of phosphorylation" ; oboInOwl:hasNarrowSynonym "activation of phosphorylation", "stimulation of phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042327" ; a owl:Class ; rdfs:label "positive regulation of phosphorylation" ; rdfs:subClassOf obo:GO_0042325, obo:GO_0045937, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016310 ] ) ] . obo:GO_0042330 obo:IAO_0000115 "The directed movement of a motile cell or organism in response to an external stimulus." ; oboInOwl:hasDbXref "Wikipedia:Taxis" ; oboInOwl:hasExactSynonym "directed movement in response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042330" ; a owl:Class ; rdfs:label "taxis" ; rdfs:subClassOf obo:GO_0040011, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009605 ] . obo:GO_0042331 obo:IAO_0000115 "The directed movement of a motile cell or organism in response to light." ; oboInOwl:hasAlternativeId "GO:0046953" ; oboInOwl:hasDbXref "Wikipedia:Phototaxis" ; oboInOwl:hasExactSynonym "phototactic behavior", "phototactic behaviour", "taxis in response to light" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042331" ; a owl:Class ; rdfs:label "phototaxis" ; rdfs:subClassOf obo:GO_0009416, obo:GO_0009453 . obo:GO_0042335 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss." ; oboInOwl:hasExactSynonym "cuticle anabolism", "cuticle biosynthesis", "cuticle biosynthetic process", "cuticle formation", "cuticle synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042335" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "cuticle development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0042338 obo:IAO_0000115 "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans." ; oboInOwl:hasBroadSynonym "cuticle anabolism during molting", "cuticle biosynthetic process during molting", "cuticle formation during molting", "cuticle synthesis during molting" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "collagen and cuticulin-based cuticle development during molting" ; oboInOwl:id "GO:0042338" ; a owl:Class ; rdfs:label "cuticle development involved in collagen and cuticulin-based cuticle molting cycle" ; rdfs:subClassOf obo:GO_0040002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0018996 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042335 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0018996 ] ) ] . obo:GO_0042401 obo:IAO_0000115 "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ; oboInOwl:hasExactSynonym "biogenic amine anabolism", "biogenic amine biosynthesis", "biogenic amine formation", "biogenic amine synthesis", "cellular biogenic amine biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042401" ; a owl:Class ; rdfs:label "biogenic amine biosynthetic process" ; rdfs:subClassOf obo:GO_0006576, obo:GO_0009309 . obo:GO_0042402 obo:IAO_0000115 "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters." ; oboInOwl:hasExactSynonym "biogenic amine breakdown", "biogenic amine catabolism", "biogenic amine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042402" ; a owl:Class ; rdfs:label "cellular biogenic amine catabolic process" ; rdfs:subClassOf obo:GO_0009310 . obo:GO_0042416 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; oboInOwl:hasExactSynonym "dopamine anabolism", "dopamine biosynthesis", "dopamine formation", "dopamine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042416" ; a owl:Class ; rdfs:label "dopamine biosynthetic process" ; rdfs:subClassOf obo:GO_0042417, obo:GO_0042423 . obo:GO_0042417 obo:IAO_0000115 "The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; oboInOwl:hasExactSynonym "dopamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042417" ; a owl:Class ; rdfs:label "dopamine metabolic process" ; rdfs:subClassOf obo:GO_0006584 . obo:GO_0042420 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; oboInOwl:hasExactSynonym "dopamine breakdown", "dopamine catabolism", "dopamine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042420" ; a owl:Class ; rdfs:label "dopamine catabolic process" ; rdfs:subClassOf obo:GO_0042417, obo:GO_0042424 . obo:GO_0042423 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; oboInOwl:hasDbXref "Wikipedia:Catecholamines" ; oboInOwl:hasExactSynonym "catecholamine anabolism", "catecholamine biosynthesis", "catecholamine formation", "catecholamine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042423" ; a owl:Class ; rdfs:label "catecholamine biosynthetic process" ; rdfs:subClassOf obo:GO_0006584, obo:GO_0009713, obo:GO_0042401 . obo:GO_0042424 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine." ; oboInOwl:hasExactSynonym "catecholamine breakdown", "catecholamine catabolism", "catecholamine degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042424" ; a owl:Class ; rdfs:label "catecholamine catabolic process" ; rdfs:subClassOf obo:GO_0006584, obo:GO_0019614, obo:GO_0042402 . obo:GO_0042427 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ; oboInOwl:hasDbXref "Wikipedia:Serotonin" ; oboInOwl:hasExactSynonym "serotonin anabolism", "serotonin biosynthesis", "serotonin formation", "serotonin synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042427" ; a owl:Class ; rdfs:label "serotonin biosynthetic process" ; rdfs:subClassOf obo:GO_0042428, obo:GO_0042435, obo:GO_0046189, obo:GO_1901162 . obo:GO_0042428 obo:IAO_0000115 "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ; oboInOwl:hasExactSynonym "serotonin metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042428" ; a owl:Class ; rdfs:label "serotonin metabolic process" ; rdfs:subClassOf obo:GO_0018958, obo:GO_0042430, obo:GO_0097164, obo:GO_1901160 . obo:GO_0042429 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties." ; oboInOwl:hasExactSynonym "serotonin breakdown", "serotonin catabolism", "serotonin degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042429" ; a owl:Class ; rdfs:label "serotonin catabolic process" ; rdfs:subClassOf obo:GO_0019336, obo:GO_0042428, obo:GO_0042436, obo:GO_1901161 . obo:GO_0042430 obo:IAO_0000115 "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton." ; oboInOwl:hasAlternativeId "GO:0042434" ; oboInOwl:hasExactSynonym "indole and derivative metabolic process", "indole and derivative metabolism", "indole-containing compound metabolism", "ketole metabolic process", "ketole metabolism" ; oboInOwl:hasNarrowSynonym "indole derivative metabolic process", "indole derivative metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042430" ; a owl:Class ; rdfs:label "indole-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006725, obo:GO_0034641, obo:GO_0046483, obo:GO_1901360, obo:GO_1901564 . obo:GO_0042435 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton." ; oboInOwl:hasExactSynonym "indole derivative biosynthesis", "indole derivative biosynthetic process", "indole-containing compound anabolism", "indole-containing compound biosynthesis", "indole-containing compound formation", "indole-containing compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042435" ; a owl:Class ; rdfs:label "indole-containing compound biosynthetic process" ; rdfs:subClassOf obo:GO_0018130, obo:GO_0019438, obo:GO_0042430, obo:GO_0044271, obo:GO_1901362, obo:GO_1901566 . obo:GO_0042436 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton." ; oboInOwl:hasExactSynonym "indole derivative catabolic process", "indole derivative catabolism", "indole-containing compound breakdown", "indole-containing compound catabolism", "indole-containing compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042436" ; a owl:Class ; rdfs:label "indole-containing compound catabolic process" ; rdfs:subClassOf obo:GO_0019439, obo:GO_0042430, obo:GO_0044270, obo:GO_0046700, obo:GO_1901361, obo:GO_1901565 . obo:GO_0042439 obo:IAO_0000115 "The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it." ; oboInOwl:hasExactSynonym "ethanolamine and derivative metabolic process", "ethanolamine and derivative metabolism", "ethanolamine-containing compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042439" ; a owl:Class ; rdfs:label "ethanolamine-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0006066, obo:GO_0006576 . obo:GO_0042445 obo:IAO_0000115 "The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23965"^^xsd:anyURI ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasAlternativeId "GO:0034754" ; oboInOwl:hasExactSynonym "hormone metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular hormone metabolic process" ; oboInOwl:id "GO:0042445" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "hormone metabolic process" ; rdfs:subClassOf obo:GO_0008152, obo:GO_0010817 . obo:GO_0042493 obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:GO_0009410 ; a owl:Class ; owl:deprecated true . obo:GO_0042551 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042551" ; a owl:Class ; rdfs:label "neuron maturation" ; rdfs:subClassOf obo:GO_0048469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ] . obo:GO_0042579 obo:IAO_0000115 "Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2)." ; oboInOwl:hasDbXref "Wikipedia:Microbody" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042579" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "microbody" ; rdfs:subClassOf obo:GO_0043231, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0042592 obo:IAO_0000115 "Any biological process involved in the maintenance of an internal steady state." ; oboInOwl:hasAlternativeId "GO:0032844", "GO:0032845", "GO:0032846" ; oboInOwl:hasExactSynonym "homeostasis" ; oboInOwl:hasNarrowSynonym "activation of homeostatic process", "inhibition of homeostatic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of homeostatic process", "positive regulation of homeostatic process", "regulation of homeostatic process" ; oboInOwl:id "GO:0042592" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_mouse ; a owl:Class ; rdfs:label "homeostatic process" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0042594 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042594" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "response to starvation" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0031667 . obo:GO_0042645 obo:IAO_0000115 "The region of a mitochondrion to which the DNA is confined." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042645" ; a owl:Class ; rdfs:label "mitochondrial nucleoid" ; rdfs:subClassOf obo:GO_0009295, obo:GO_0043232, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005759 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009295 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0042659 obo:IAO_0000115 "Any process that mediates the adoption of a specific fate by a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042659" ; a owl:Class ; rdfs:label "regulation of cell fate specification" ; rdfs:subClassOf obo:GO_0010453, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001708 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001708 ] ) ] . obo:GO_0042660 obo:IAO_0000115 "Any process that activates or enables a cell to adopt a specific fate." ; oboInOwl:hasExactSynonym "up regulation of cell fate specification", "up-regulation of cell fate specification", "upregulation of cell fate specification" ; oboInOwl:hasNarrowSynonym "activation of cell fate specification", "stimulation of cell fate specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042660" ; a owl:Class ; rdfs:label "positive regulation of cell fate specification" ; rdfs:subClassOf obo:GO_0010455, obo:GO_0042659, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001708 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001708 ] ) ] . obo:GO_0042692 obo:IAO_0000115 "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "myogenesis" ; oboInOwl:id "GO:0042692" ; a owl:Class ; rdfs:label "muscle cell differentiation" ; rdfs:subClassOf obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061061 ] . obo:GO_0042713 obo:IAO_0000115 "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042713" ; a owl:Class ; rdfs:label "sperm ejaculation" ; rdfs:subClassOf obo:GO_0048609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007320 ] . obo:GO_0042752 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042752" ; a owl:Class ; rdfs:label "regulation of circadian rhythm" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007623 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007623 ] ) ] . obo:GO_0042753 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior." ; oboInOwl:hasExactSynonym "up regulation of circadian rhythm", "up-regulation of circadian rhythm", "upregulation of circadian rhythm" ; oboInOwl:hasNarrowSynonym "activation of circadian rhythm", "stimulation of circadian rhythm" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042753" ; a owl:Class ; rdfs:label "positive regulation of circadian rhythm" ; rdfs:subClassOf obo:GO_0042752, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007623 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007623 ] ) ] . obo:GO_0042754 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior." ; oboInOwl:hasExactSynonym "down regulation of circadian rhythm", "down-regulation of circadian rhythm", "downregulation of circadian rhythm" ; oboInOwl:hasNarrowSynonym "inhibition of circadian rhythm" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042754" ; a owl:Class ; rdfs:label "negative regulation of circadian rhythm" ; rdfs:subClassOf obo:GO_0042752, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007623 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007623 ] ) ] . obo:GO_0042755 obo:IAO_0000115 "The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue." ; oboInOwl:hasExactSynonym "eating behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042755" ; a owl:Class ; rdfs:label "eating behavior" ; rdfs:subClassOf obo:GO_0007631 . obo:GO_0042770 obo:IAO_0000115 "A cascade of processes induced by the detection of DNA damage within a cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17715"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006975" ; oboInOwl:hasExactSynonym "DNA damage response, signal transduction", "response to DNA damage stimulus by intracellular signaling cascade" ; oboInOwl:hasNarrowSynonym "DNA damage induced protein phosphorylation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042770" ; a owl:Class ; rdfs:label "signal transduction in response to DNA damage" ; rdfs:subClassOf obo:GO_0006974, obo:GO_0035556 . obo:GO_0042810 obo:IAO_0000115 "The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process." ; oboInOwl:hasExactSynonym "pheromone metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0042810" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "pheromone metabolic process" ; rdfs:subClassOf obo:GO_0019748, obo:GO_0042445, obo:GO_0044237 . obo:GO_0042981 obo:IAO_0000115 "Any process that modulates the occurrence or rate of cell death by apoptotic process." ; oboInOwl:hasNarrowSynonym "regulation of apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "apoptosis regulator activity" ; oboInOwl:id "GO:0042981" ; a owl:Class ; rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used." ; rdfs:label "regulation of apoptotic process" ; rdfs:subClassOf obo:GO_0043067, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006915 ] ) ] . obo:GO_0042995 obo:IAO_0000115 "A prolongation or process extending from a cell, e.g. a flagellum or axon." ; oboInOwl:hasBroadSynonym "cell process", "cellular process" ; oboInOwl:hasExactSynonym "cellular projection" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0042995" ; oboInOwl:inSubset go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "cell projection" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0043005 obo:IAO_0000115 "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "NIF_Subcellular:sao867568886" ; oboInOwl:hasExactSynonym "neuron process", "neuron protrusion", "neuronal cell projection" ; oboInOwl:hasNarrowSynonym "neurite" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "nerve fiber" ; oboInOwl:id "GO:0043005" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "neuron projection" ; rdfs:subClassOf obo:GO_0120025 . obo:GO_0043043 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide." ; oboInOwl:hasExactSynonym "peptide anabolism", "peptide biosynthesis", "peptide formation", "peptide synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043043" ; a owl:Class ; rdfs:label "peptide biosynthetic process" ; rdfs:subClassOf obo:GO_0006518, obo:GO_0043604, obo:GO_1901566 . obo:GO_0043050 obo:IAO_0000115 "The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pumping behavior" ; oboInOwl:id "GO:0043050" ; a owl:Class ; rdfs:label "nematode pharyngeal pumping" ; rdfs:subClassOf obo:GO_0042755 . obo:GO_0043051 obo:IAO_0000115 "Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043051" ; a owl:Class ; rdfs:label "regulation of nematode pharyngeal pumping" ; rdfs:subClassOf obo:GO_1903998, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043050 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043050 ] ) ] . obo:GO_0043052 obo:IAO_0000115 "The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature." ; oboInOwl:hasDbXref "Wikipedia:Thermotaxis" ; oboInOwl:hasExactSynonym "taxis in response to temperature stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043052" ; a owl:Class ; rdfs:label "thermotaxis" ; rdfs:subClassOf obo:GO_0009266, obo:GO_0042330 . obo:GO_0043053 obo:IAO_0000115 "Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development." ; oboInOwl:hasExactSynonym "nematode entry into dormancy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043053" ; a owl:Class ; rdfs:label "dauer entry" ; rdfs:subClassOf obo:GO_0055115, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0040024 ] . obo:GO_0043054 obo:IAO_0000115 "Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development." ; oboInOwl:hasExactSynonym "exit from nematode dormancy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043054" ; a owl:Class ; rdfs:label "dauer exit" ; rdfs:subClassOf obo:GO_0071981, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0040024 ] . obo:GO_0043057 obo:IAO_0000115 "Posterior movement of an organism, e.g. following the direction of the tail of an animal." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043057" ; a owl:Class ; rdfs:label "backward locomotion" ; rdfs:subClassOf obo:GO_0033058 . obo:GO_0043058 obo:IAO_0000115 "Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043058" ; a owl:Class ; rdfs:label "regulation of backward locomotion" ; rdfs:subClassOf obo:GO_0040012, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043057 ] ) ] . obo:GO_0043065 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process." ; oboInOwl:hasExactSynonym "up regulation of apoptosis", "up-regulation of apoptosis", "upregulation of apoptosis" ; oboInOwl:hasNarrowSynonym "activation of apoptosis", "positive regulation of apoptosis", "stimulation of apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pro-apoptosis" ; oboInOwl:id "GO:0043065" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used." ; rdfs:label "positive regulation of apoptotic process" ; rdfs:subClassOf obo:GO_0042981, obo:GO_0043068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006915 ] ) ] . obo:GO_0043066 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process." ; oboInOwl:hasAlternativeId "GO:0006916" ; oboInOwl:hasExactSynonym "anti-apoptosis", "down regulation of apoptosis", "down-regulation of apoptosis", "downregulation of apoptosis" ; oboInOwl:hasNarrowSynonym "inhibition of apoptosis", "negative regulation of apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "apoptosis inhibitor activity", "pro-survival" ; oboInOwl:id "GO:0043066" ; a owl:Class ; rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used." ; rdfs:label "negative regulation of apoptotic process" ; rdfs:subClassOf obo:GO_0042981, obo:GO_0043069, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006915 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006915 ] ) ] . obo:GO_0043067 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ; oboInOwl:hasAlternativeId "GO:0043070" ; oboInOwl:hasNarrowSynonym "regulation of non-apoptotic programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043067" ; a owl:Class ; rdfs:label "regulation of programmed cell death" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0012501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0012501 ] ) ] . obo:GO_0043068 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ; oboInOwl:hasAlternativeId "GO:0043071" ; oboInOwl:hasExactSynonym "up regulation of programmed cell death", "up-regulation of programmed cell death", "upregulation of programmed cell death" ; oboInOwl:hasNarrowSynonym "activation of programmed cell death", "positive regulation of non-apoptotic programmed cell death", "stimulation of programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043068" ; a owl:Class ; rdfs:label "positive regulation of programmed cell death" ; rdfs:subClassOf obo:GO_0043067, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0012501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0012501 ] ) ] . obo:GO_0043069 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes." ; oboInOwl:hasAlternativeId "GO:0043072" ; oboInOwl:hasExactSynonym "down regulation of programmed cell death", "down-regulation of programmed cell death", "downregulation of programmed cell death" ; oboInOwl:hasNarrowSynonym "inhibition of programmed cell death", "negative regulation of non-apoptotic programmed cell death" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043069" ; a owl:Class ; rdfs:label "negative regulation of programmed cell death" ; rdfs:subClassOf obo:GO_0043067, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0012501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0012501 ] ) ] . obo:GO_0043085 obo:IAO_0000115 "Any process that activates or increases the activity of an enzyme." ; oboInOwl:hasAlternativeId "GO:0048554" ; oboInOwl:hasExactSynonym "positive regulation of enzyme activity", "up regulation of enzyme activity", "up-regulation of enzyme activity", "upregulation of enzyme activity" ; oboInOwl:hasNarrowSynonym "activation of enzyme activity", "activation of metalloenzyme activity", "positive regulation of metalloenzyme activity", "stimulation of enzyme activity", "stimulation of metalloenzyme activity", "up regulation of metalloenzyme activity", "up-regulation of metalloenzyme activity", "upregulation of metalloenzyme activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043085" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_chembl ; a owl:Class ; rdfs:label "positive regulation of catalytic activity" ; rdfs:subClassOf obo:GO_0044093, obo:GO_0050790, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003824 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003824 ] ) ] . obo:GO_0043086 obo:IAO_0000115 "Any process that stops or reduces the activity of an enzyme." ; oboInOwl:hasAlternativeId "GO:0048553" ; oboInOwl:hasExactSynonym "down regulation of enzyme activity", "down-regulation of enzyme activity", "down-regulation of metalloenzyme activity", "downregulation of enzyme activity", "negative regulation of enzyme activity" ; oboInOwl:hasNarrowSynonym "down regulation of metalloenzyme activity", "downregulation of metalloenzyme activity", "inhibition of enzyme activity", "inhibition of metalloenzyme activity", "negative regulation of metalloenzyme activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043086" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of catalytic activity" ; rdfs:subClassOf obo:GO_0044092, obo:GO_0050790, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003824 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003824 ] ) ] . obo:GO_0043143 obo:IAO_0000115 "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "establishment and maintenance of translational machinery localization", "establishment and maintenance of translational protein localization", "regulation of translation by machinery localisation", "translational machinery localization", "translational protein localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043143" ; a owl:Class ; rdfs:label "regulation of translation by machinery localization" ; rdfs:subClassOf obo:GO_0006417, obo:GO_0008104, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006412 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0008104 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0043170 obo:IAO_0000115 "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasAlternativeId "GO:0034960", "GO:0043283", "GO:0044259" ; oboInOwl:hasExactSynonym "biopolymer metabolic process", "macromolecule metabolism", "organismal macromolecule metabolism" ; oboInOwl:hasNarrowSynonym "multicellular organismal macromolecule metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043170" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "macromolecule metabolic process" ; rdfs:subClassOf obo:GO_0071704 . obo:GO_0043186 obo:IAO_0000115 "A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes." ; oboInOwl:hasAlternativeId "GO:0018994" ; oboInOwl:hasBroadSynonym "germline granule" ; oboInOwl:hasNarrowSynonym "nuage", "polar granule" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043186" ; a owl:Class ; rdfs:label "P granule" ; rdfs:subClassOf obo:GO_0036464, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060293 ] . obo:GO_0043207 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043207" ; a owl:Class ; rdfs:label "response to external biotic stimulus" ; rdfs:subClassOf obo:GO_0009605, obo:GO_0009607 . obo:GO_0043226 obo:IAO_0000115 "Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane." ; oboInOwl:hasDbXref "NIF_Subcellular:sao1539965131", "Wikipedia:Organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043226" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "organelle" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0043227 obo:IAO_0000115 "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." ; oboInOwl:hasDbXref "NIF_Subcellular:sao414196390" ; oboInOwl:hasExactSynonym "membrane-enclosed organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043227" ; a owl:Class ; rdfs:label "membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043226, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043226 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0043228 obo:IAO_0000115 "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21881"^^xsd:anyURI ; oboInOwl:hasDbXref "NIF_Subcellular:sao1456184038" ; oboInOwl:hasExactSynonym "non-membrane-enclosed organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "biological condensate" ; oboInOwl:id "GO:0043228" ; oboInOwl:inSubset go:goslim_mouse ; a owl:Class ; rdfs:label "non-membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043226 . obo:GO_0043229 obo:IAO_0000115 "Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043229" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "intracellular organelle" ; rdfs:subClassOf obo:GO_0043226, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043226 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0043231 obo:IAO_0000115 "Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane." ; oboInOwl:hasExactSynonym "intracellular membrane-enclosed organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043231" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "intracellular membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043227, obo:GO_0043229 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043227 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0043232 obo:IAO_0000115 "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes." ; oboInOwl:hasExactSynonym "intracellular non-membrane-enclosed organelle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043232" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "intracellular non-membrane-bounded organelle" ; rdfs:subClassOf obo:GO_0043228, obo:GO_0043229 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043228 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0043233 obo:IAO_0000115 "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043233" ; oboInOwl:inSubset go:goslim_mouse ; a owl:Class ; rdfs:label "organelle lumen" ; rdfs:subClassOf obo:GO_0031974, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031974 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0043242 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ; oboInOwl:hasExactSynonym "down regulation of protein complex disassembly", "down-regulation of protein complex disassembly", "downregulation of protein complex disassembly" ; oboInOwl:hasNarrowSynonym "inhibition of protein complex disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of protein complex disassembly" ; oboInOwl:id "GO:0043242" ; a owl:Class ; rdfs:label "negative regulation of protein-containing complex disassembly" ; rdfs:subClassOf obo:GO_0043244, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032984 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032984 ] ) ] . obo:GO_0043243 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ; oboInOwl:hasExactSynonym "up regulation of protein complex disassembly", "up-regulation of protein complex disassembly", "upregulation of protein complex disassembly" ; oboInOwl:hasNarrowSynonym "activation of protein complex disassembly", "stimulation of protein complex disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of protein complex disassembly" ; oboInOwl:id "GO:0043243" ; a owl:Class ; rdfs:label "positive regulation of protein-containing complex disassembly" ; rdfs:subClassOf obo:GO_0043244, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032984 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032984 ] ) ] . obo:GO_0043244 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of protein complex disassembly" ; oboInOwl:id "GO:0043244" ; a owl:Class ; rdfs:label "regulation of protein-containing complex disassembly" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032984 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032984 ] ) ] . obo:GO_0043254 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein complex assembly." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of protein complex assembly" ; oboInOwl:id "GO:0043254" ; a owl:Class ; rdfs:label "regulation of protein-containing complex assembly" ; rdfs:subClassOf obo:GO_0044087, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0065003 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0065003 ] ) ] . obo:GO_0043277 obo:IAO_0000115 "The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte." ; oboInOwl:hasExactSynonym "apoptotic cell removal", "efferocytosis", "programmed cell clearance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043277" ; a owl:Class ; rdfs:comment "Note that unlike mammals or Drosophila, C. elegans (and many lower organisms) do not have professional macrophages/phagocytes, instead cell corpses are engulfed by neighboring cells. Cell types that can function as engulfing cells include hypodermal cells, gonadal sheath cells, pharyngeal muscle cells, and intestinal cells." ; rdfs:label "apoptotic cell clearance" ; rdfs:subClassOf obo:GO_0006909 . obo:GO_0043292 obo:IAO_0000115 "Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle." ; oboInOwl:hasExactSynonym "contractile fibre" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043292" ; a owl:Class ; rdfs:label "contractile fiber" ; rdfs:subClassOf obo:GO_0043232, obo:GO_0099512, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] . obo:GO_0043296 obo:IAO_0000115 "A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability." ; oboInOwl:hasExactSynonym "apical cell junction complex", "apical junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0043296" ; a owl:Class ; rdfs:label "apical junction complex" ; rdfs:subClassOf obo:GO_0005911 . obo:GO_0043393 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein binding." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043393" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "regulation of protein binding" ; rdfs:subClassOf obo:GO_0051098, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005515 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005515 ] ) ] . obo:GO_0043412 obo:IAO_0000115 "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043412" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "macromolecule modification" ; rdfs:subClassOf obo:GO_0043170 . obo:GO_0043414 obo:IAO_0000115 "The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043414" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "macromolecule methylation" ; rdfs:subClassOf obo:GO_0032259, obo:GO_0043412 . obo:GO_0043455 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon." ; oboInOwl:hasExactSynonym "regulation of secondary metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043455" ; a owl:Class ; rdfs:label "regulation of secondary metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019748 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019748 ] ) ] . obo:GO_0043473 obo:IAO_0000115 "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043473" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_pir ; a owl:Class ; rdfs:label "pigmentation" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0043484 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043484" ; a owl:Class ; rdfs:label "regulation of RNA splicing" ; rdfs:subClassOf obo:GO_0010468, obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008380 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008380 ] ) ] . obo:GO_0043523 obo:IAO_0000115 "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons." ; oboInOwl:hasExactSynonym "regulation of apoptosis of neuronal cells", "regulation of apoptosis of neurons", "regulation of neuron programmed cell death", "regulation of neuronal cell programmed cell death", "regulation of programmed cell death of neuronal cells", "regulation of programmed cell death, neurons" ; oboInOwl:hasNarrowSynonym "regulation of neuron apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043523" ; a owl:Class ; rdfs:label "regulation of neuron apoptotic process" ; rdfs:subClassOf obo:GO_0042981, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051402 ] ) ] . obo:GO_0043524 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons." ; oboInOwl:hasExactSynonym "down regulation of neuron apoptosis", "down-regulation of neuron apoptosis", "downregulation of neuron apoptosis", "negative regulation of programmed cell death, neurons" ; oboInOwl:hasNarrowSynonym "inhibition of neuron apoptosis", "negative regulation of neuron apoptosis", "neuron survival" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043524" ; a owl:Class ; rdfs:label "negative regulation of neuron apoptotic process" ; rdfs:subClassOf obo:GO_0043066, obo:GO_0043523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051402 ] ) ] . obo:GO_0043525 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process." ; oboInOwl:hasExactSynonym "positive regulation of programmed cell death, neurons", "up regulation of neuron apoptosis", "up-regulation of neuron apoptosis", "upregulation of neuron apoptosis" ; oboInOwl:hasNarrowSynonym "activation of neuron apoptosis", "positive regulation of neuron apoptosis", "stimulation of neuron apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043525" ; a owl:Class ; rdfs:label "positive regulation of neuron apoptotic process" ; rdfs:subClassOf obo:GO_0043065, obo:GO_0043523, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051402 ] ) ] . obo:GO_0043555 obo:IAO_0000115 "Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:hasExactSynonym "translational stress response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043555" ; a owl:Class ; rdfs:label "regulation of translation in response to stress" ; rdfs:subClassOf obo:GO_0006417, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0043556 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043556" ; a owl:Class ; rdfs:label "regulation of translation in response to oxidative stress" ; rdfs:subClassOf obo:GO_0032055, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034599 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0043557 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043557" ; a owl:Class ; rdfs:label "regulation of translation in response to osmotic stress" ; rdfs:subClassOf obo:GO_0043555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071470 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0071470 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0043603 obo:IAO_0000115 "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells." ; oboInOwl:hasExactSynonym "amide metabolism", "cellular amide metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043603" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "amide metabolic process" ; rdfs:subClassOf obo:GO_0006807 . obo:GO_0043604 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043604" ; a owl:Class ; rdfs:label "amide biosynthetic process" ; rdfs:subClassOf obo:GO_0043603, obo:GO_0044271 . obo:GO_0043652 obo:IAO_0000115 "The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte." ; oboInOwl:hasExactSynonym "engulfment of apoptotic cell corpse", "engulfment of cell corpse" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0043652" ; a owl:Class ; rdfs:comment "This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'." ; rdfs:label "engulfment of apoptotic cell" ; rdfs:subClassOf obo:GO_0006911, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043277 ] . obo:GO_0043933 obo:IAO_0000115 "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22580"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-08T10:01:42Z" ; oboInOwl:hasAlternativeId "GO:0034600", "GO:0034621", "GO:0071822" ; oboInOwl:hasExactSynonym "protein complex subunit organisation", "protein complex subunit organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular macromolecular complex organization", "cellular macromolecular complex subunit organisation", "cellular macromolecular complex subunit organization", "macromolecular complex organization", "macromolecular complex subunit organisation", "macromolecular complex subunit organization", "protein-containing complex subunit organization" ; oboInOwl:id "GO:0043933" ; a owl:Class ; rdfs:label "protein-containing complex organization" ; rdfs:subClassOf obo:GO_0016043 . obo:GO_0044057 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044057" ; a owl:Class ; rdfs:label "regulation of system process" ; rdfs:subClassOf obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003008 ] ) ] . obo:GO_0044058 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044058" ; a owl:Class ; rdfs:label "regulation of digestive system process" ; rdfs:subClassOf obo:GO_0044057, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022600 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022600 ] ) ] . obo:GO_0044062 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044062" ; a owl:Class ; rdfs:label "regulation of excretion" ; rdfs:subClassOf obo:GO_0044057, obo:GO_0051046, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007588 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007588 ] ) ] . obo:GO_0044085 obo:IAO_0000115 "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component." ; oboInOwl:hasAlternativeId "GO:0071843" ; oboInOwl:hasExactSynonym "cellular component biogenesis at cellular level" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044085" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular component biogenesis" ; rdfs:subClassOf obo:GO_0071840 . obo:GO_0044087 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044087" ; a owl:Class ; rdfs:label "regulation of cellular component biogenesis" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044085 ] ) ] . obo:GO_0044088 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." ; oboInOwl:hasExactSynonym "regulation of vacuole organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of vacuole biogenesis" ; oboInOwl:id "GO:0044088" ; a owl:Class ; rdfs:label "regulation of vacuole organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007033 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007033 ] ) ] . obo:GO_0044089 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044089" ; a owl:Class ; rdfs:label "positive regulation of cellular component biogenesis" ; rdfs:subClassOf obo:GO_0044087, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044085 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044085 ] ) ] . obo:GO_0044090 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole." ; oboInOwl:hasExactSynonym "positive regulation of vacuole organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of vacuole biogenesis" ; oboInOwl:id "GO:0044090" ; a owl:Class ; rdfs:label "positive regulation of vacuole organization" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0044088, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007033 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007033 ] ) ] . obo:GO_0044091 obo:IAO_0000115 "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044091" ; a owl:Class ; rdfs:label "membrane biogenesis" ; rdfs:subClassOf obo:GO_0044085 . obo:GO_0044092 obo:IAO_0000115 "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2009-04-21T04:07:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044092" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of molecular function" ; rdfs:subClassOf obo:GO_0065009, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0003674 ] ) ] . obo:GO_0044093 obo:IAO_0000115 "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2009-04-21T04:11:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044093" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of molecular function" ; rdfs:subClassOf obo:GO_0065009, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0003674 ] ) ] . obo:GO_0044237 obo:IAO_0000115 "The chemical reactions and pathways by which individual cells transform chemical substances." ; oboInOwl:hasExactSynonym "cellular metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intermediary metabolism" ; oboInOwl:id "GO:0044237" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term." ; rdfs:label "cellular metabolic process" ; rdfs:subClassOf obo:GO_0008152, obo:GO_0009987 . obo:GO_0044238 obo:IAO_0000115 "The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ; oboInOwl:hasExactSynonym "primary metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044238" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "primary metabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0044248 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "cellular breakdown", "cellular catabolism", "cellular degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044248" ; a owl:Class ; rdfs:label "cellular catabolic process" ; rdfs:subClassOf obo:GO_0009056, obo:GO_0044237 . obo:GO_0044249 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells." ; oboInOwl:hasExactSynonym "cellular anabolism", "cellular biosynthesis", "cellular formation", "cellular synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044249" ; a owl:Class ; rdfs:label "cellular biosynthetic process" ; rdfs:subClassOf obo:GO_0009058, obo:GO_0044237 . obo:GO_0044270 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds." ; oboInOwl:hasBroadSynonym "nitrogen compound breakdown", "nitrogen compound catabolism", "nitrogen compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044270" ; a owl:Class ; rdfs:label "cellular nitrogen compound catabolic process" ; rdfs:subClassOf obo:GO_0034641, obo:GO_0044248 . obo:GO_0044271 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds." ; oboInOwl:hasBroadSynonym "nitrogen compound anabolism", "nitrogen compound biosynthesis", "nitrogen compound formation", "nitrogen compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044271" ; a owl:Class ; rdfs:label "cellular nitrogen compound biosynthetic process" ; rdfs:subClassOf obo:GO_0034641, obo:GO_0044249 . obo:GO_0044281 obo:IAO_0000115 "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-01-26T12:05:20Z" ; oboInOwl:hasExactSynonym "small molecule metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044281" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_metagenomics ; a owl:Class ; rdfs:comment "Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides." ; rdfs:label "small molecule metabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0044419 obo:IAO_0000115 "Any process evolved to enable an interaction with an organism of a different species." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20191"^^xsd:anyURI ; obo:RO_0002161 obo:NCBITaxon_4895 ; oboInOwl:hasExactSynonym "interaction with another species", "interspecies interaction", "interspecies interaction between organisms", "interspecies interaction with other organisms" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044419" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_candida, go:goslim_pir ; a owl:Class ; rdfs:label "biological process involved in interspecies interaction between organisms" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0044703 obo:IAO_0000115 "A biological process that directly contributes to the process of producing new individuals, involving another organism." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T15:56:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044703" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "multi-organism reproductive process" ; rdfs:subClassOf obo:GO_0022414 . obo:GO_0044706 obo:IAO_0000115 "A multicellular organism process which involves another multicellular organism of the same or different species." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21459"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2012-09-19T16:06:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044706" ; a owl:Class ; rdfs:label "multi-multicellular organism process" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0044770 obo:IAO_0000115 "The cell cycle process by which a cell commits to entering the next cell cycle phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T12:54:59Z" ; oboInOwl:hasExactSynonym "cell cycle transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044770" ; a owl:Class ; rdfs:label "cell cycle phase transition" ; rdfs:subClassOf obo:GO_0022402 . obo:GO_0044771 obo:IAO_0000115 "The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T13:08:17Z" ; oboInOwl:hasBroadSynonym "cell cycle transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044771" ; a owl:Class ; rdfs:label "meiotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_0044770, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044770 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0044772 obo:IAO_0000115 "The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T13:09:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044772" ; oboInOwl:inSubset go:goslim_pombe ; a owl:Class ; rdfs:label "mitotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_0044770, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044770 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0044773 obo:IAO_0000115 "A signal transduction process involved in mitotic DNA damage checkpoint." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T15:55:25Z" ; oboInOwl:hasAlternativeId "GO:1902402" ; oboInOwl:hasExactSynonym "intracellular signaling cascade involved in mitotic DNA damage checkpoint", "mitotic DNA damage checkpoint", "signal transduction involved in mitotic DNA damage checkpoint" ; oboInOwl:hasNarrowSynonym "intracellular signal transduction pathway involved in mitotic DNA damage checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intracellular signaling pathway involved in mitotic DNA damage checkpoint" ; oboInOwl:id "GO:0044773" ; a owl:Class ; rdfs:label "mitotic DNA damage checkpoint signaling" ; rdfs:subClassOf obo:GO_0000077, obo:GO_0044774 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0044774 obo:IAO_0000115 "A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-02-28T16:07:26Z" ; oboInOwl:hasAlternativeId "GO:0070683", "GO:1902403" ; oboInOwl:hasExactSynonym "intracellular signal transduction involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signal transduction involved in topo II checkpoint", "intracellular signal transduction pathway involved in mitotic DNA integrity checkpoint", "intracellular signaling cascade involved in mitotic DNA integrity checkpoint", "intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signaling cascade involved in topo II checkpoint", "intracellular signaling chain involved in mitotic DNA integrity checkpoint", "intracellular signaling chain involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signaling pathway involved in mitotic DNA integrity checkpoint", "mitotic DNA integrity checkpoint", "mitotic cell cycle G2/M transition decatenation checkpoint", "signal transduction involved in mitotic DNA integrity checkpoint" ; oboInOwl:hasNarrowSynonym "intracellular signal transduction pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signal transduction pathway involved in topo II checkpoint", "intracellular signal transduction pathway involved in topoisomerase II checkpoint", "intracellular signaling pathway involved in topo II checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intracellular signaling pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint", "intracellular signaling pathway involved in topoisomerase II checkpoint", "signal transduction via intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint", "signal transduction via intracellular signaling cascade involved in topo II checkpoint" ; oboInOwl:id "GO:0044774" ; a owl:Class ; rdfs:label "mitotic DNA integrity checkpoint signaling" ; rdfs:subClassOf obo:GO_0007093, obo:GO_0031570 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031570 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0044778 obo:IAO_0000115 "A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-20T16:46:06Z" ; oboInOwl:hasExactSynonym "meiotic DNA integrity checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044778" ; a owl:Class ; rdfs:label "meiotic DNA integrity checkpoint signaling" ; rdfs:subClassOf obo:GO_0031570, obo:GO_0033313 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031570 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0044779 obo:IAO_0000115 "A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-21T14:01:28Z" ; oboInOwl:hasAlternativeId "GO:1902398" ; oboInOwl:hasExactSynonym "intracellular signal transduction involved in meiotic spindle checkpoint", "intracellular signal transduction pathway involved in meiotic spindle checkpoint", "intracellular signaling cascade involved in meiotic spindle checkpoint", "intracellular signaling pathway involved in meiotic spindle checkpoint", "meiotic spindle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044779" ; a owl:Class ; rdfs:label "meiotic spindle checkpoint signaling" ; rdfs:subClassOf obo:GO_0031577, obo:GO_0033313, obo:GO_1902103 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031577 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0044782 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-27T15:09:58Z" ; oboInOwl:hasExactSynonym "microtubule-based flagellum organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044782" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "cilium organization" ; rdfs:subClassOf obo:GO_0006996, obo:GO_0120036 . obo:GO_0044784 obo:IAO_0000115 "The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T13:09:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044784" ; a owl:Class ; rdfs:label "metaphase/anaphase transition of cell cycle" ; rdfs:subClassOf obo:GO_0033045, obo:GO_0044770 . obo:GO_0044785 obo:IAO_0000115 "The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T13:11:28Z" ; oboInOwl:hasExactSynonym "meiotic metaphase/anaphase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044785" ; a owl:Class ; rdfs:label "metaphase/anaphase transition of meiotic cell cycle" ; rdfs:subClassOf obo:GO_0044771, obo:GO_0044784 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0044784 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0044786 obo:IAO_0000115 "The DNA-dependent DNA replication that takes place as part of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T15:52:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044786" ; a owl:Class ; rdfs:label "cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0006261, obo:GO_0022402 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006261 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0044818 obo:IAO_0000115 "A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-11-19T14:20:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044818" ; a owl:Class ; rdfs:label "mitotic G2/M transition checkpoint" ; rdfs:subClassOf obo:GO_0007093, obo:GO_0010972 . obo:GO_0044819 obo:IAO_0000115 "A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-11-19T14:31:14Z" ; oboInOwl:hasExactSynonym "mitotic G1/S transition checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044819" ; a owl:Class ; rdfs:label "mitotic G1/S transition checkpoint signaling" ; rdfs:subClassOf obo:GO_0007093, obo:GO_2000134 . obo:GO_0044839 obo:IAO_0000115 "The cell cycle process by which a cell in G2 phase commits to M phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-05T14:56:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044839" ; a owl:Class ; rdfs:label "cell cycle G2/M phase transition" ; rdfs:subClassOf obo:GO_0044770 . obo:GO_0044840 obo:IAO_0000115 "A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-25T11:56:41Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0044840" ; a owl:Class ; rdfs:label "gut granule" ; rdfs:subClassOf obo:GO_0031410 . obo:GO_0044841 obo:IAO_0000115 "The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-25T12:02:05Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0044841" ; a owl:Class ; rdfs:label "gut granule membrane" ; rdfs:subClassOf obo:GO_0030659, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044840 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031090 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044840 ] ) ] . obo:GO_0044842 obo:IAO_0000115 "The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-25T12:02:32Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0044842" ; a owl:Class ; rdfs:label "gut granule lumen" ; rdfs:subClassOf obo:GO_0070013, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044840 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0043233 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044840 ] ) ] . obo:GO_0044843 obo:IAO_0000115 "The cell cycle process by which a cell in G1 phase commits to S phase." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-25T16:33:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044843" ; a owl:Class ; rdfs:label "cell cycle G1/S phase transition" ; rdfs:subClassOf obo:GO_0044770 . obo:GO_0044848 obo:IAO_0000115 "A distinct period or stage in a biological process or cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-07-16T13:12:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0044848" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase." ; rdfs:label "biological phase" ; rdfs:subClassOf obo:GO_0008150 ; owl:disjointWith obo:GO_0048511, obo:GO_0050896, obo:GO_0051179, obo:GO_0071840 . obo:GO_0045026 obo:IAO_0000115 "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell." ; oboInOwl:hasAlternativeId "GO:0006947" ; oboInOwl:hasBroadSynonym "cell fusion", "cell-cell fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045026" ; a owl:Class ; rdfs:label "plasma membrane fusion" ; rdfs:subClassOf obo:GO_0007009, obo:GO_0061025 . obo:GO_0045055 obo:IAO_0000115 "A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand." ; oboInOwl:hasExactSynonym "regulated secretory pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045055" ; a owl:Class ; rdfs:label "regulated exocytosis" ; rdfs:subClassOf obo:GO_0006887 . obo:GO_0045087 obo:IAO_0000115 "Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens." ; obo:RO_0002161 obo:NCBITaxon_Union_0000023 ; oboInOwl:hasAlternativeId "GO:0002226" ; oboInOwl:hasDbXref "Wikipedia:Innate_immune_system" ; oboInOwl:hasExactSynonym "innate immunity", "nonspecific immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045087" ; a owl:Class ; rdfs:label "innate immune response" ; rdfs:subClassOf obo:GO_0006955, obo:GO_0098542 . obo:GO_0045088 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045088" ; a owl:Class ; rdfs:label "regulation of innate immune response" ; rdfs:subClassOf obo:GO_0002831, obo:GO_0031347, obo:GO_0032101, obo:GO_0050776, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045087 ] ) ] . obo:GO_0045089 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection." ; oboInOwl:hasExactSynonym "up regulation of innate immune response", "up-regulation of innate immune response", "upregulation of innate immune response" ; oboInOwl:hasNarrowSynonym "stimulation of innate immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045089" ; a owl:Class ; rdfs:label "positive regulation of innate immune response" ; rdfs:subClassOf obo:GO_0002833, obo:GO_0031349, obo:GO_0032103, obo:GO_0045088, obo:GO_0050778, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045087 ] ) ] . obo:GO_0045120 obo:IAO_0000115 "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents." ; oboInOwl:hasDbXref "Wikipedia:Pronucleus" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0045120" ; a owl:Class ; rdfs:label "pronucleus" ; rdfs:subClassOf obo:GO_0005634 . obo:GO_0045132 obo:IAO_0000115 "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045132" ; a owl:Class ; rdfs:label "meiotic chromosome segregation" ; rdfs:subClassOf obo:GO_0098813, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098813 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0045137 obo:IAO_0000115 "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045137" ; a owl:Class ; rdfs:label "development of primary sexual characteristics" ; rdfs:subClassOf obo:GO_0003006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007548 ] . obo:GO_0045143 obo:IAO_0000115 "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." ; oboInOwl:hasAlternativeId "GO:0007061" ; oboInOwl:hasExactSynonym "meiosis I, chromosome segregation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045143" ; a owl:Class ; rdfs:label "homologous chromosome segregation" ; rdfs:subClassOf obo:GO_0045132, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098813 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0045161 obo:IAO_0000115 "The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045161" ; a owl:Class ; rdfs:label "neuronal ion channel clustering" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042551 ] . obo:GO_0045165 obo:IAO_0000115 "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045165" ; a owl:Class ; rdfs:comment "Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created." ; rdfs:label "cell fate commitment" ; rdfs:subClassOf obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030154 ] . obo:GO_0045168 obo:IAO_0000115 "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate." ; oboInOwl:hasExactSynonym "cell fate commitment, cell-cell signaling", "cell fate commitment, cell-cell signalling", "cell-cell signaling during in cell fate commitment", "cell-cell signaling resulting in cell fate commitment", "cell-cell signalling during cell fate commitment", "cell-cell signalling resulting in cell fate commitment" ; oboInOwl:hasNarrowSynonym "cell-cell signalling involved in cell fate specification" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045168" ; a owl:Class ; rdfs:label "cell-cell signaling involved in cell fate commitment" ; rdfs:subClassOf obo:GO_0007267, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045165 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045165 ] ) ] . obo:GO_0045184 obo:IAO_0000115 "The directed movement of a protein to a specific location." ; oboInOwl:hasExactSynonym "establishment of protein localisation", "protein positioning", "protein recruitment" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045184" ; a owl:Class ; rdfs:label "establishment of protein localization" ; rdfs:subClassOf obo:GO_0008104, obo:GO_0051234 . obo:GO_0045185 obo:IAO_0000115 "Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away." ; oboInOwl:hasNarrowSynonym "active protein retrieval", "protein retention", "protein sequestering" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "maintenance of protein localization" ; oboInOwl:id "GO:0045185" ; a owl:Class ; rdfs:label "maintenance of protein location" ; rdfs:subClassOf obo:GO_0051235, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008104 ] . obo:GO_0045202 obo:IAO_0000115 "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane." ; oboInOwl:hasDbXref "NIF_Subcellular:sao914572699", "Wikipedia:Chemical_synapse" ; oboInOwl:hasExactSynonym "synaptic junction" ; oboInOwl:hasNarrowSynonym "mixed synapse" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "electrotonic synapse" ; oboInOwl:id "GO:0045202" ; oboInOwl:inSubset go:goslim_agr, go:goslim_drosophila, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir, go:goslim_synapse ; a owl:Class ; rdfs:label "synapse" ; rdfs:subClassOf obo:GO_0030054 . obo:GO_0045495 obo:IAO_0000115 "Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo." ; obo:RO_0002161 obo:NCBITaxon_4751 ; oboInOwl:hasExactSynonym "polar plasm" ; oboInOwl:hasNarrowSynonym "germ plasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0045495" ; a owl:Class ; rdfs:label "pole plasm" ; rdfs:subClassOf obo:GO_0005737 . obo:GO_0045595 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045595" ; a owl:Class ; rdfs:label "regulation of cell differentiation" ; rdfs:subClassOf obo:GO_0050793, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030154 ] ) ] . obo:GO_0045596 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of cell differentiation", "down-regulation of cell differentiation", "downregulation of cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045596" ; a owl:Class ; rdfs:label "negative regulation of cell differentiation" ; rdfs:subClassOf obo:GO_0045595, obo:GO_0048523, obo:GO_0051093, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030154 ] ) ] . obo:GO_0045597 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of cell differentiation", "up-regulation of cell differentiation", "upregulation of cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of cell differentiation", "stimulation of cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045597" ; a owl:Class ; rdfs:label "positive regulation of cell differentiation" ; rdfs:subClassOf obo:GO_0045595, obo:GO_0048522, obo:GO_0051094, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030154 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030154 ] ) ] . obo:GO_0045664 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of neuron differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045664" ; a owl:Class ; rdfs:label "regulation of neuron differentiation" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030182 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030182 ] ) ] . obo:GO_0045665 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation." ; oboInOwl:hasExactSynonym "down regulation of neuron differentiation", "down-regulation of neuron differentiation", "downregulation of neuron differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of neuron differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045665" ; a owl:Class ; rdfs:label "negative regulation of neuron differentiation" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0045664, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030182 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030182 ] ) ] . obo:GO_0045666 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of neuron differentiation." ; oboInOwl:hasExactSynonym "up regulation of neuron differentiation", "up-regulation of neuron differentiation", "upregulation of neuron differentiation" ; oboInOwl:hasNarrowSynonym "activation of neuron differentiation", "stimulation of neuron differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045666" ; a owl:Class ; rdfs:label "positive regulation of neuron differentiation" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0045664, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030182 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030182 ] ) ] . obo:GO_0045700 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045700" ; a owl:Class ; rdfs:label "regulation of spermatid nuclear differentiation" ; rdfs:subClassOf obo:GO_0051239, obo:GO_1903353, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007289 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007289 ] ) ] . obo:GO_0045701 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation." ; oboInOwl:hasExactSynonym "down regulation of spermatid nuclear differentiation", "down-regulation of spermatid nuclear differentiation", "downregulation of spermatid nuclear differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of spermatid nuclear differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045701" ; a owl:Class ; rdfs:label "negative regulation of spermatid nuclear differentiation" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0045596, obo:GO_0045700, obo:GO_0051241, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007289 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007289 ] ) ] . obo:GO_0045702 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation." ; oboInOwl:hasExactSynonym "up regulation of spermatid nuclear differentiation", "up-regulation of spermatid nuclear differentiation", "upregulation of spermatid nuclear differentiation" ; oboInOwl:hasNarrowSynonym "activation of spermatid nuclear differentiation", "stimulation of spermatid nuclear differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045702" ; a owl:Class ; rdfs:label "positive regulation of spermatid nuclear differentiation" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0045597, obo:GO_0045700, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007289 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007289 ] ) ] . obo:GO_0045727 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA." ; oboInOwl:hasAlternativeId "GO:0045946" ; oboInOwl:hasExactSynonym "positive regulation of protein anabolism", "positive regulation of protein biosynthesis", "positive regulation of protein biosynthetic process", "positive regulation of protein formation", "positive regulation of protein synthesis", "up regulation of protein biosynthetic process", "up-regulation of protein biosynthetic process", "upregulation of protein biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of protein biosynthetic process", "stimulation of protein biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045727" ; a owl:Class ; rdfs:label "positive regulation of translation" ; rdfs:subClassOf obo:GO_0006417, obo:GO_0010628, obo:GO_0034250, obo:GO_0051247, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0045732 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:1903364", "GO:2000600" ; oboInOwl:hasExactSynonym "positive regulation of cellular protein breakdown", "positive regulation of cellular protein catabolic process", "positive regulation of cellular protein catabolism", "positive regulation of cellular protein degradation", "positive regulation of protein breakdown", "positive regulation of protein catabolism", "positive regulation of protein degradation", "up regulation of cellular protein breakdown", "up regulation of cellular protein catabolic process", "up regulation of cellular protein catabolism", "up regulation of cellular protein degradation", "up regulation of protein catabolic process", "up-regulation of cellular protein breakdown", "up-regulation of cellular protein catabolic process", "up-regulation of cellular protein catabolism", "up-regulation of cellular protein degradation", "up-regulation of protein catabolic process", "upregulation of cellular protein breakdown", "upregulation of cellular protein catabolic process", "upregulation of cellular protein catabolism", "upregulation of cellular protein degradation", "upregulation of protein catabolic process" ; oboInOwl:hasNarrowSynonym "activation of cellular protein breakdown", "activation of cellular protein catabolic process", "activation of cellular protein catabolism", "activation of cellular protein degradation", "activation of protein catabolic process", "positive regulation of cyclin breakdown", "positive regulation of cyclin catabolic process", "positive regulation of cyclin catabolism", "positive regulation of cyclin degradation", "positive regulation of degradation of cyclin", "stimulation of protein catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045732" ; a owl:Class ; rdfs:label "positive regulation of protein catabolic process" ; rdfs:subClassOf obo:GO_0009896, obo:GO_0042176, obo:GO_0051247, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030163 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030163 ] ) ] . obo:GO_0045740 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of DNA replication." ; oboInOwl:hasExactSynonym "up regulation of DNA replication", "up-regulation of DNA replication", "upregulation of DNA replication" ; oboInOwl:hasNarrowSynonym "activation of DNA replication", "stimulation of DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045740" ; a owl:Class ; rdfs:label "positive regulation of DNA replication" ; rdfs:subClassOf obo:GO_0006275, obo:GO_0051054, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006260 ] ) ] . obo:GO_0045769 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division." ; oboInOwl:hasExactSynonym "down regulation of asymmetric cell division", "down-regulation of asymmetric cell division", "downregulation of asymmetric cell division" ; oboInOwl:hasNarrowSynonym "inhibition of asymmetric cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045769" ; a owl:Class ; rdfs:label "negative regulation of asymmetric cell division" ; rdfs:subClassOf obo:GO_0009786, obo:GO_0051782, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008356 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008356 ] ) ] . obo:GO_0045770 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of asymmetric cell division." ; oboInOwl:hasExactSynonym "up regulation of asymmetric cell division", "up-regulation of asymmetric cell division", "upregulation of asymmetric cell division" ; oboInOwl:hasNarrowSynonym "activation of asymmetric cell division", "stimulation of asymmetric cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045770" ; a owl:Class ; rdfs:label "positive regulation of asymmetric cell division" ; rdfs:subClassOf obo:GO_0009786, obo:GO_0051781, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008356 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008356 ] ) ] . obo:GO_0045773 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of axon extension." ; oboInOwl:hasExactSynonym "up regulation of axon extension", "up-regulation of axon extension", "upregulation of axon extension" ; oboInOwl:hasNarrowSynonym "activation of axon extension", "stimulation of axon extension" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045773" ; a owl:Class ; rdfs:label "positive regulation of axon extension" ; rdfs:subClassOf obo:GO_0030307, obo:GO_0030516, obo:GO_0048639, obo:GO_0050772, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048675 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048675 ] ) ] . obo:GO_0045785 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell adhesion." ; oboInOwl:hasExactSynonym "up regulation of cell adhesion", "up-regulation of cell adhesion", "upregulation of cell adhesion" ; oboInOwl:hasNarrowSynonym "activation of cell adhesion", "stimulation of cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045785" ; a owl:Class ; rdfs:label "positive regulation of cell adhesion" ; rdfs:subClassOf obo:GO_0030155, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007155 ] ) ] . obo:GO_0045786 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle." ; oboInOwl:hasExactSynonym "down regulation of progression through cell cycle", "down-regulation of progression through cell cycle", "downregulation of progression through cell cycle", "negative regulation of cell cycle progression", "negative regulation of progression through cell cycle" ; oboInOwl:hasNarrowSynonym "inhibition of progression through cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045786" ; a owl:Class ; rdfs:label "negative regulation of cell cycle" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0051726, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0045787 obo:IAO_0000115 "Any process that activates or increases the rate or extent of progression through the cell cycle." ; oboInOwl:hasExactSynonym "positive regulation of cell cycle progression", "positive regulation of progression through cell cycle", "up regulation of progression through cell cycle", "up-regulation of progression through cell cycle", "upregulation of progression through cell cycle" ; oboInOwl:hasNarrowSynonym "activation of progression through cell cycle", "stimulation of progression through cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045787" ; a owl:Class ; rdfs:label "positive regulation of cell cycle" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0051726, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0045806 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis." ; oboInOwl:hasExactSynonym "down regulation of endocytosis", "down-regulation of endocytosis", "downregulation of endocytosis" ; oboInOwl:hasNarrowSynonym "inhibition of endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045806" ; a owl:Class ; rdfs:label "negative regulation of endocytosis" ; rdfs:subClassOf obo:GO_0030100, obo:GO_0051051, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006897 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006897 ] ) ] . obo:GO_0045807 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of endocytosis." ; oboInOwl:hasExactSynonym "up regulation of endocytosis", "up-regulation of endocytosis", "upregulation of endocytosis" ; oboInOwl:hasNarrowSynonym "activation of endocytosis", "stimulation of endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045807" ; a owl:Class ; rdfs:label "positive regulation of endocytosis" ; rdfs:subClassOf obo:GO_0030100, obo:GO_0051050, obo:GO_0051130, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006897 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006897 ] ) ] . obo:GO_0045824 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response." ; oboInOwl:hasExactSynonym "down regulation of innate immune response", "down-regulation of innate immune response", "downregulation of innate immune response" ; oboInOwl:hasNarrowSynonym "inhibition of innate immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045824" ; a owl:Class ; rdfs:label "negative regulation of innate immune response" ; rdfs:subClassOf obo:GO_0002832, obo:GO_0031348, obo:GO_0032102, obo:GO_0045088, obo:GO_0050777, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045087 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045087 ] ) ] . obo:GO_0045833 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids." ; oboInOwl:hasExactSynonym "down regulation of lipid metabolic process", "down-regulation of lipid metabolic process", "downregulation of lipid metabolic process", "negative regulation of lipid metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of lipid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045833" ; a owl:Class ; rdfs:label "negative regulation of lipid metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0019216, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006629 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006629 ] ) ] . obo:GO_0045834 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids." ; oboInOwl:hasExactSynonym "positive regulation of lipid metabolism", "up regulation of lipid metabolic process", "up-regulation of lipid metabolic process", "upregulation of lipid metabolic process" ; oboInOwl:hasNarrowSynonym "activation of lipid metabolic process", "stimulation of lipid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045834" ; a owl:Class ; rdfs:label "positive regulation of lipid metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0019216, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006629 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006629 ] ) ] . obo:GO_0045835 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis." ; oboInOwl:hasExactSynonym "down regulation of meiosis", "down-regulation of meiosis", "downregulation of meiosis", "negative regulation of meiosis" ; oboInOwl:hasNarrowSynonym "inhibition of meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045835" ; a owl:Class ; rdfs:label "negative regulation of meiotic nuclear division" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0040020, obo:GO_0051447, obo:GO_0051784, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0140013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0045836 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of meiosis." ; oboInOwl:hasExactSynonym "positive regulation of meiosis", "up regulation of meiosis", "up-regulation of meiosis", "upregulation of meiosis" ; oboInOwl:hasNarrowSynonym "activation of meiosis", "stimulation of meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045836" ; a owl:Class ; rdfs:label "positive regulation of meiotic nuclear division" ; rdfs:subClassOf obo:GO_0040020, obo:GO_0051446, obo:GO_0051785, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0140013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0045839 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother." ; oboInOwl:hasExactSynonym "down regulation of mitosis", "down-regulation of mitosis", "downregulation of mitosis", "negative regulation of mitosis" ; oboInOwl:hasNarrowSynonym "inhibition of mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045839" ; a owl:Class ; rdfs:label "negative regulation of mitotic nuclear division" ; rdfs:subClassOf obo:GO_0007088, obo:GO_0010948, obo:GO_0045930, obo:GO_0051784, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0045840 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitosis." ; oboInOwl:hasExactSynonym "positive regulation of mitosis", "up regulation of mitosis", "up-regulation of mitosis", "upregulation of mitosis" ; oboInOwl:hasNarrowSynonym "activation of mitosis", "mitogenic activity", "stimulation of mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045840" ; a owl:Class ; rdfs:label "positive regulation of mitotic nuclear division" ; rdfs:subClassOf obo:GO_0007088, obo:GO_0051785, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0045841 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ; oboInOwl:hasExactSynonym "down regulation of mitotic metaphase/anaphase transition", "down-regulation of mitotic metaphase/anaphase transition", "downregulation of mitotic metaphase/anaphase transition" ; oboInOwl:hasNarrowSynonym "inhibition of mitotic metaphase/anaphase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045841" ; a owl:Class ; rdfs:label "negative regulation of mitotic metaphase/anaphase transition" ; rdfs:subClassOf obo:GO_0030071, obo:GO_0045839, obo:GO_1901991, obo:GO_1902100, obo:GO_2000816, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007091 ] ) ] . obo:GO_0045842 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin." ; oboInOwl:hasExactSynonym "up regulation of mitotic metaphase/anaphase transition", "up-regulation of mitotic metaphase/anaphase transition", "upregulation of mitotic metaphase/anaphase transition" ; oboInOwl:hasNarrowSynonym "activation of mitotic metaphase/anaphase transition", "stimulation of mitotic metaphase/anaphase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045842" ; a owl:Class ; rdfs:label "positive regulation of mitotic metaphase/anaphase transition" ; rdfs:subClassOf obo:GO_0030071, obo:GO_0045840, obo:GO_1901970, obo:GO_1901992, obo:GO_1902101, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007091 ] ) ] . obo:GO_0045892 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription." ; oboInOwl:hasAlternativeId "GO:0016481", "GO:0032582", "GO:0061021" ; oboInOwl:hasExactSynonym "down regulation of transcription, DNA-dependent", "down-regulation of transcription, DNA-dependent", "downregulation of transcription, DNA-dependent", "negative regulation of cellular transcription, DNA-dependent", "negative regulation of transcription, DNA-dependent", "negative regulation of transcription, DNA-templated" ; oboInOwl:hasNarrowSynonym "inhibition of transcription, DNA-dependent" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of gene-specific transcription", "down-regulation of gene-specific transcription", "downregulation of gene-specific transcription", "inhibition of gene-specific transcription", "negative regulation of gene-specific transcription", "transcription repressor activity" ; oboInOwl:id "GO:0045892" ; a owl:Class ; rdfs:label "negative regulation of DNA-templated transcription" ; rdfs:subClassOf obo:GO_0006355, obo:GO_1902679, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006351 ] ) ] . obo:GO_0045893 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription." ; oboInOwl:hasAlternativeId "GO:0043193", "GO:0045941", "GO:0061020" ; oboInOwl:hasExactSynonym "positive regulation of cellular transcription, DNA-dependent", "positive regulation of transcription, DNA-dependent", "positive regulation of transcription, DNA-templated", "up regulation of transcription, DNA-dependent", "up-regulation of transcription, DNA-dependent", "upregulation of transcription, DNA-dependent" ; oboInOwl:hasNarrowSynonym "activation of transcription, DNA-dependent", "stimulation of gene-specific transcription", "stimulation of transcription, DNA-dependent" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of gene-specific transcription", "positive regulation of gene-specific transcription", "transcription activator activity", "up regulation of gene-specific transcription", "up-regulation of gene-specific transcription", "upregulation of gene-specific transcription" ; oboInOwl:id "GO:0045893" ; a owl:Class ; rdfs:label "positive regulation of DNA-templated transcription" ; rdfs:subClassOf obo:GO_0006355, obo:GO_1902680, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006351 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006351 ] ) ] . obo:GO_0045900 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation." ; oboInOwl:hasExactSynonym "down regulation of translational elongation", "down-regulation of translational elongation", "downregulation of translational elongation" ; oboInOwl:hasNarrowSynonym "inhibition of translational elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045900" ; a owl:Class ; rdfs:label "negative regulation of translational elongation" ; rdfs:subClassOf obo:GO_0006448, obo:GO_0017148, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006414 ] ) ] . obo:GO_0045901 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of translational elongation." ; oboInOwl:hasExactSynonym "up regulation of translational elongation", "up-regulation of translational elongation", "upregulation of translational elongation" ; oboInOwl:hasNarrowSynonym "activation of translational elongation", "stimulation of translational elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045901" ; a owl:Class ; rdfs:label "positive regulation of translational elongation" ; rdfs:subClassOf obo:GO_0006448, obo:GO_0045727, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006414 ] ) ] . obo:GO_0045910 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination." ; oboInOwl:hasExactSynonym "down regulation of DNA recombination", "down-regulation of DNA recombination", "downregulation of DNA recombination" ; oboInOwl:hasNarrowSynonym "inhibition of DNA recombination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045910" ; a owl:Class ; rdfs:label "negative regulation of DNA recombination" ; rdfs:subClassOf obo:GO_0000018, obo:GO_0051053, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006310 ] ) ] . obo:GO_0045911 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of DNA recombination." ; oboInOwl:hasExactSynonym "up regulation of DNA recombination", "up-regulation of DNA recombination", "upregulation of DNA recombination" ; oboInOwl:hasNarrowSynonym "activation of DNA recombination", "stimulation of DNA recombination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045911" ; a owl:Class ; rdfs:label "positive regulation of DNA recombination" ; rdfs:subClassOf obo:GO_0000018, obo:GO_0051054, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006310 ] ) ] . obo:GO_0045914 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." ; oboInOwl:hasExactSynonym "down regulation of catecholamine metabolic process", "down-regulation of catecholamine metabolic process", "downregulation of catecholamine metabolic process", "negative regulation of catecholamine metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of catecholamine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045914" ; a owl:Class ; rdfs:label "negative regulation of catecholamine metabolic process" ; rdfs:subClassOf obo:GO_0031324, obo:GO_0033239, obo:GO_0042069, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006584 ] ) ] . obo:GO_0045915 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine." ; oboInOwl:hasExactSynonym "positive regulation of catecholamine metabolism", "up regulation of catecholamine metabolic process", "up-regulation of catecholamine metabolic process", "upregulation of catecholamine metabolic process" ; oboInOwl:hasNarrowSynonym "activation of catecholamine metabolic process", "stimulation of catecholamine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045915" ; a owl:Class ; rdfs:label "positive regulation of catecholamine metabolic process" ; rdfs:subClassOf obo:GO_0031325, obo:GO_0033240, obo:GO_0042069, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006584 ] ) ] . obo:GO_0045920 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis." ; oboInOwl:hasExactSynonym "down regulation of exocytosis", "down-regulation of exocytosis", "downregulation of exocytosis" ; oboInOwl:hasNarrowSynonym "inhibition of exocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045920" ; a owl:Class ; rdfs:label "negative regulation of exocytosis" ; rdfs:subClassOf obo:GO_0017157, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006887 ] ) ] . obo:GO_0045921 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of exocytosis." ; oboInOwl:hasExactSynonym "up regulation of exocytosis", "up-regulation of exocytosis", "upregulation of exocytosis" ; oboInOwl:hasNarrowSynonym "activation of exocytosis", "stimulation of exocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045921" ; a owl:Class ; rdfs:label "positive regulation of exocytosis" ; rdfs:subClassOf obo:GO_0017157, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006887 ] ) ] . obo:GO_0045926 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism." ; oboInOwl:hasExactSynonym "down regulation of growth", "down-regulation of growth", "downregulation of growth" ; oboInOwl:hasNarrowSynonym "inhibition of growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045926" ; a owl:Class ; rdfs:label "negative regulation of growth" ; rdfs:subClassOf obo:GO_0040008, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040007 ] ) ] . obo:GO_0045927 obo:IAO_0000115 "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism." ; oboInOwl:hasExactSynonym "up regulation of growth", "up-regulation of growth", "upregulation of growth" ; oboInOwl:hasNarrowSynonym "activation of growth", "stimulation of growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045927" ; a owl:Class ; rdfs:label "positive regulation of growth" ; rdfs:subClassOf obo:GO_0040008, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040007 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040007 ] ) ] . obo:GO_0045930 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle." ; oboInOwl:hasExactSynonym "down regulation of progression through mitotic cell cycle", "down-regulation of progression through mitotic cell cycle", "downregulation of progression through mitotic cell cycle", "negative regulation of mitotic cell cycle progression", "negative regulation of progression through mitotic cell cycle" ; oboInOwl:hasNarrowSynonym "inhibition of progression through mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045930" ; a owl:Class ; rdfs:label "negative regulation of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0007346, obo:GO_0045786, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0045931 obo:IAO_0000115 "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle." ; oboInOwl:hasExactSynonym "positive regulation of mitotic cell cycle progression", "positive regulation of progression through mitotic cell cycle", "up regulation of progression through mitotic cell cycle", "up-regulation of progression through mitotic cell cycle", "upregulation of progression through mitotic cell cycle" ; oboInOwl:hasNarrowSynonym "activation of progression through mitotic cell cycle", "stimulation of progression through mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045931" ; a owl:Class ; rdfs:label "positive regulation of mitotic cell cycle" ; rdfs:subClassOf obo:GO_0007346, obo:GO_0045787, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0045932 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction." ; oboInOwl:hasExactSynonym "down regulation of muscle contraction", "down-regulation of muscle contraction", "downregulation of muscle contraction" ; oboInOwl:hasNarrowSynonym "inhibition of muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045932" ; a owl:Class ; rdfs:label "negative regulation of muscle contraction" ; rdfs:subClassOf obo:GO_0006937, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006936 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006936 ] ) ] . obo:GO_0045933 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of muscle contraction." ; oboInOwl:hasExactSynonym "up regulation of muscle contraction", "up-regulation of muscle contraction", "upregulation of muscle contraction" ; oboInOwl:hasNarrowSynonym "activation of muscle contraction", "stimulation of muscle contraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045933" ; a owl:Class ; rdfs:label "positive regulation of muscle contraction" ; rdfs:subClassOf obo:GO_0006937, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006936 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006936 ] ) ] . obo:GO_0045934 obo:IAO_0000115 "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:id "GO:0045934" ; a owl:Class ; rdfs:label "negative regulation of nucleobase-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0019219, obo:GO_0031324, obo:GO_0051172, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006139 ] ) ] . obo:GO_0045935 obo:IAO_0000115 "Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids." ; oboInOwl:hasExactSynonym "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism", "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:hasNarrowSynonym "activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process", "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process" ; oboInOwl:id "GO:0045935" ; a owl:Class ; rdfs:label "positive regulation of nucleobase-containing compound metabolic process" ; rdfs:subClassOf obo:GO_0019219, obo:GO_0031325, obo:GO_0051173, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006139 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006139 ] ) ] . obo:GO_0045936 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ; oboInOwl:hasExactSynonym "down regulation of phosphate metabolic process", "down-regulation of phosphate metabolic process", "downregulation of phosphate metabolic process", "negative regulation of phosphate metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of phosphate metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045936" ; a owl:Class ; rdfs:label "negative regulation of phosphate metabolic process" ; rdfs:subClassOf obo:GO_0010563, obo:GO_0019220, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006796 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006796 ] ) ] . obo:GO_0045937 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates." ; oboInOwl:hasExactSynonym "positive regulation of phosphate metabolism", "up regulation of phosphate metabolic process", "up-regulation of phosphate metabolic process", "upregulation of phosphate metabolic process" ; oboInOwl:hasNarrowSynonym "activation of phosphate metabolic process", "stimulation of phosphate metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045937" ; a owl:Class ; rdfs:label "positive regulation of phosphate metabolic process" ; rdfs:subClassOf obo:GO_0010562, obo:GO_0019220, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006796 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006796 ] ) ] . obo:GO_0045963 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ; oboInOwl:hasExactSynonym "down regulation of dopamine metabolic process", "down-regulation of dopamine metabolic process", "downregulation of dopamine metabolic process", "negative regulation of dopamine metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of dopamine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045963" ; a owl:Class ; rdfs:label "negative regulation of dopamine metabolic process" ; rdfs:subClassOf obo:GO_0042053, obo:GO_0045914, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042417 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042417 ] ) ] . obo:GO_0045964 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine." ; oboInOwl:hasExactSynonym "positive regulation of dopamine metabolism", "up regulation of dopamine metabolic process", "up-regulation of dopamine metabolic process", "upregulation of dopamine metabolic process" ; oboInOwl:hasNarrowSynonym "activation of dopamine metabolic process", "stimulation of dopamine metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045964" ; a owl:Class ; rdfs:label "positive regulation of dopamine metabolic process" ; rdfs:subClassOf obo:GO_0042053, obo:GO_0045915, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042417 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042417 ] ) ] . obo:GO_0045992 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development." ; oboInOwl:hasExactSynonym "down regulation of embryonic development", "down-regulation of embryonic development", "downregulation of embryonic development" ; oboInOwl:hasNarrowSynonym "inhibition of embryonic development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045992" ; a owl:Class ; rdfs:label "negative regulation of embryonic development" ; rdfs:subClassOf obo:GO_0045995, obo:GO_0051093, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009790 ] ) ] . obo:GO_0045995 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of embryonic development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0045995" ; a owl:Class ; rdfs:label "regulation of embryonic development" ; rdfs:subClassOf obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009790 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009790 ] ) ] . obo:GO_0046189 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring." ; oboInOwl:hasExactSynonym "phenol-containing compound anabolism", "phenol-containing compound biosynthesis", "phenol-containing compound formation", "phenol-containing compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046189" ; a owl:Class ; rdfs:label "phenol-containing compound biosynthetic process" ; rdfs:subClassOf obo:GO_0018958, obo:GO_0019438, obo:GO_1901362, obo:GO_1901617 . obo:GO_0046333 obo:IAO_0000115 "The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species." ; oboInOwl:hasExactSynonym "octopamine metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046333" ; a owl:Class ; rdfs:label "octopamine metabolic process" ; rdfs:subClassOf obo:GO_0018958, obo:GO_0042439 . obo:GO_0046483 obo:IAO_0000115 "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." ; oboInOwl:hasExactSynonym "heterocycle metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046483" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "heterocycle metabolic process" ; rdfs:subClassOf obo:GO_0044237 . obo:GO_0046546 obo:IAO_0000115 "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046546" ; a owl:Class ; rdfs:label "development of primary male sexual characteristics" ; rdfs:subClassOf obo:GO_0045137, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0046661 ] . obo:GO_0046661 obo:IAO_0000115 "The establishment of the sex of a male organism by physical differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046661" ; a owl:Class ; rdfs:label "male sex differentiation" ; rdfs:subClassOf obo:GO_0007548, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0046662 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium." ; oboInOwl:hasAlternativeId "GO:0048042" ; oboInOwl:hasExactSynonym "regulation of oviposition" ; oboInOwl:hasNarrowSynonym "regulation of post-mating oviposition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046662" ; a owl:Class ; rdfs:label "regulation of egg-laying behavior" ; rdfs:subClassOf obo:GO_0050795, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0018991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0018991 ] ) ] . obo:GO_0046700 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings)." ; oboInOwl:hasExactSynonym "heterocycle breakdown", "heterocycle catabolism", "heterocycle degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046700" ; a owl:Class ; rdfs:label "heterocycle catabolic process" ; rdfs:subClassOf obo:GO_0044248, obo:GO_0046483 . obo:GO_0046785 obo:IAO_0000115 "The addition of tubulin heterodimers to one or both ends of a microtubule." ; oboInOwl:hasExactSynonym "microtubule assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microtubule formation" ; oboInOwl:id "GO:0046785" ; a owl:Class ; rdfs:label "microtubule polymerization" ; rdfs:subClassOf obo:GO_0031109, obo:GO_0051258, obo:GO_0097435 . obo:GO_0046822 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046822" ; a owl:Class ; rdfs:label "regulation of nucleocytoplasmic transport" ; rdfs:subClassOf obo:GO_0032386, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006913 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006913 ] ) ] . obo:GO_0046823 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus." ; oboInOwl:hasExactSynonym "down regulation of nucleocytoplasmic transport", "down-regulation of nucleocytoplasmic transport", "downregulation of nucleocytoplasmic transport" ; oboInOwl:hasNarrowSynonym "inhibition of nucleocytoplasmic transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046823" ; a owl:Class ; rdfs:label "negative regulation of nucleocytoplasmic transport" ; rdfs:subClassOf obo:GO_0032387, obo:GO_0046822, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006913 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006913 ] ) ] . obo:GO_0046824 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm." ; oboInOwl:hasExactSynonym "up regulation of nucleocytoplasmic transport", "up-regulation of nucleocytoplasmic transport", "upregulation of nucleocytoplasmic transport" ; oboInOwl:hasNarrowSynonym "activation of nucleocytoplasmic transport", "stimulation of nucleocytoplasmic transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046824" ; a owl:Class ; rdfs:label "positive regulation of nucleocytoplasmic transport" ; rdfs:subClassOf obo:GO_0032388, obo:GO_0046822, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006913 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006913 ] ) ] . obo:GO_0046825 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm." ; oboInOwl:hasExactSynonym "regulation of protein export from cell nucleus", "regulation of protein export out of nucleus", "regulation of protein transport from nucleus to cytoplasm", "regulation of protein-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046825" ; a owl:Class ; rdfs:label "regulation of protein export from nucleus" ; rdfs:subClassOf obo:GO_0033157, obo:GO_0046822, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006611 ] ) ] . obo:GO_0046826 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm." ; oboInOwl:hasExactSynonym "down regulation of protein export from nucleus", "down-regulation of protein export from nucleus", "downregulation of protein export from nucleus", "negative regulation of protein export from cell nucleus", "negative regulation of protein export out of nucleus", "negative regulation of protein transport from nucleus to cytoplasm", "negative regulation of protein-nucleus export" ; oboInOwl:hasNarrowSynonym "inhibition of protein export from nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046826" ; a owl:Class ; rdfs:label "negative regulation of protein export from nucleus" ; rdfs:subClassOf obo:GO_0046823, obo:GO_0046825, obo:GO_0051457, obo:GO_0090317, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006611 ] ) ] . obo:GO_0046827 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm." ; oboInOwl:hasExactSynonym "positive regulation of protein export from cell nucleus", "positive regulation of protein export out of nucleus", "positive regulation of protein transport from nucleus to cytoplasm", "positive regulation of protein-nucleus export", "up regulation of protein export from nucleus", "up-regulation of protein export from nucleus", "upregulation of protein export from nucleus" ; oboInOwl:hasNarrowSynonym "activation of protein export from nucleus", "stimulation of protein export from nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046827" ; a owl:Class ; rdfs:label "positive regulation of protein export from nucleus" ; rdfs:subClassOf obo:GO_0046824, obo:GO_0046825, obo:GO_0090316, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006611 ] ) ] . obo:GO_0046831 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm." ; oboInOwl:hasExactSynonym "regulation of RNA export from cell nucleus", "regulation of RNA export out of nucleus", "regulation of RNA transport from nucleus to cytoplasm", "regulation of RNA-nucleus export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046831" ; a owl:Class ; rdfs:label "regulation of RNA export from nucleus" ; rdfs:subClassOf obo:GO_0032239, obo:GO_0046822, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006405 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006405 ] ) ] . obo:GO_0046832 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm." ; oboInOwl:hasExactSynonym "down regulation of RNA export from nucleus", "down-regulation of RNA export from nucleus", "downregulation of RNA export from nucleus", "negative regulation of RNA export from cell nucleus", "negative regulation of RNA export out of nucleus", "negative regulation of RNA transport from nucleus to cytoplasm", "negative regulation of RNA-nucleus export" ; oboInOwl:hasNarrowSynonym "inhibition of RNA export from nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046832" ; a owl:Class ; rdfs:label "negative regulation of RNA export from nucleus" ; rdfs:subClassOf obo:GO_0032240, obo:GO_0046823, obo:GO_0046831, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006405 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006405 ] ) ] . obo:GO_0046833 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm." ; oboInOwl:hasExactSynonym "positive regulation of RNA export from cell nucleus", "positive regulation of RNA export out of nucleus", "positive regulation of RNA transport from nucleus to cytoplasm", "positive regulation of RNA-nucleus export", "up regulation of RNA export from nucleus", "up-regulation of RNA export from nucleus", "upregulation of RNA export from nucleus" ; oboInOwl:hasNarrowSynonym "activation of RNA export from nucleus", "stimulation of RNA export from nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046833" ; a owl:Class ; rdfs:label "positive regulation of RNA export from nucleus" ; rdfs:subClassOf obo:GO_0032241, obo:GO_0046824, obo:GO_0046831, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006405 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006405 ] ) ] . obo:GO_0046889 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ; oboInOwl:hasExactSynonym "positive regulation of lipid anabolism", "positive regulation of lipid biosynthesis", "positive regulation of lipid formation", "positive regulation of lipid synthesis", "positive regulation of lipogenesis", "up regulation of lipid biosynthetic process", "up-regulation of lipid biosynthetic process", "upregulation of lipid biosynthetic process" ; oboInOwl:hasNarrowSynonym "activation of lipid biosynthetic process", "stimulation of lipid biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046889" ; a owl:Class ; rdfs:label "positive regulation of lipid biosynthetic process" ; rdfs:subClassOf obo:GO_0009891, obo:GO_0045834, obo:GO_0046890, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008610 ] ) ] . obo:GO_0046890 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ; oboInOwl:hasExactSynonym "regulation of lipid anabolism", "regulation of lipid biosynthesis", "regulation of lipid formation", "regulation of lipid synthesis", "regulation of lipogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046890" ; a owl:Class ; rdfs:label "regulation of lipid biosynthetic process" ; rdfs:subClassOf obo:GO_0009889, obo:GO_0019216, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008610 ] ) ] . obo:GO_0046903 obo:IAO_0000115 "The controlled release of a substance by a cell or a tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046903" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "secretion" ; rdfs:subClassOf obo:GO_0006810 . obo:GO_0046907 obo:IAO_0000115 "The directed movement of substances within a cell." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-18T14:04:50Z" ; oboInOwl:hasAlternativeId "GO:1902582" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism intracellular transport", "single-organism intracellular transport" ; oboInOwl:id "GO:0046907" ; a owl:Class ; rdfs:label "intracellular transport" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0006810, obo:GO_0051641, obo:GO_0051649, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006810 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0046928 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046928" ; a owl:Class ; rdfs:label "regulation of neurotransmitter secretion" ; rdfs:subClassOf obo:GO_0050804, obo:GO_0051588, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007269 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007269 ] ) ] . obo:GO_0046929 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter." ; oboInOwl:hasExactSynonym "down regulation of neurotransmitter secretion", "down-regulation of neurotransmitter secretion", "downregulation of neurotransmitter secretion" ; oboInOwl:hasNarrowSynonym "conotoxin activity", "inhibition of neurotransmitter secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046929" ; a owl:Class ; rdfs:label "negative regulation of neurotransmitter secretion" ; rdfs:subClassOf obo:GO_0046928, obo:GO_0051589, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007269 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007269 ] ) ] . obo:GO_0046958 obo:IAO_0000115 "A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment." ; oboInOwl:hasExactSynonym "unconditional response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046958" ; a owl:Class ; rdfs:label "nonassociative learning" ; rdfs:subClassOf obo:GO_0007612 . obo:GO_0046959 obo:IAO_0000115 "A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented." ; oboInOwl:hasDbXref "Wikipedia:Habituation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0046959" ; a owl:Class ; rdfs:label "habituation" ; rdfs:subClassOf obo:GO_0046958 . obo:GO_0047484 obo:IAO_0000115 "Any process that modulates the rate or extent of the response to osmotic stress." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0047484" ; a owl:Class ; rdfs:label "regulation of response to osmotic stress" ; rdfs:subClassOf obo:GO_0080134, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006970 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006970 ] ) ] . obo:GO_0047496 obo:IAO_0000115 "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination." ; oboInOwl:hasExactSynonym "microtubule-based vesicle localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0047496" ; a owl:Class ; rdfs:label "vesicle transport along microtubule" ; rdfs:subClassOf obo:GO_0072384, obo:GO_0099518 . obo:GO_0048024 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism." ; oboInOwl:hasAlternativeId "GO:0035055" ; oboInOwl:hasBroadSynonym "regulation of pre-mRNA splicing" ; oboInOwl:hasExactSynonym "regulation of nuclear mRNA splicing, via spliceosome" ; oboInOwl:hasNarrowSynonym "regulation of nuclear mRNA splicing via U2-type spliceosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048024" ; a owl:Class ; rdfs:label "regulation of mRNA splicing, via spliceosome" ; rdfs:subClassOf obo:GO_0043484, obo:GO_0050684, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000398 ] ) ] . obo:GO_0048025 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism." ; oboInOwl:hasAlternativeId "GO:0035056" ; oboInOwl:hasBroadSynonym "negative regulation of pre-mRNA splicing" ; oboInOwl:hasExactSynonym "down regulation of nuclear mRNA splicing, via spliceosome", "down-regulation of nuclear mRNA splicing, via spliceosome", "downregulation of nuclear mRNA splicing, via spliceosome", "negative regulation of nuclear mRNA splicing, via spliceosome" ; oboInOwl:hasNarrowSynonym "down regulation of nuclear mRNA splicing via U2-type spliceosome", "down-regulation of nuclear mRNA splicing via U2-type spliceosome", "downregulation of nuclear mRNA splicing via U2-type spliceosome", "inhibition of nuclear mRNA splicing via U2-type spliceosome", "inhibition of nuclear mRNA splicing, via spliceosome", "negative regulation of nuclear mRNA splicing via U2-type spliceosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048025" ; a owl:Class ; rdfs:label "negative regulation of mRNA splicing, via spliceosome" ; rdfs:subClassOf obo:GO_0033119, obo:GO_0048024, obo:GO_0050686, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000398 ] ) ] . obo:GO_0048026 obo:IAO_0000115 "Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism." ; oboInOwl:hasAlternativeId "GO:0035057" ; oboInOwl:hasBroadSynonym "positive regulation of pre-mRNA splicing" ; oboInOwl:hasExactSynonym "positive regulation of nuclear mRNA splicing, via spliceosome", "up regulation of nuclear mRNA splicing, via spliceosome", "up-regulation of nuclear mRNA splicing, via spliceosome", "upregulation of nuclear mRNA splicing, via spliceosome" ; oboInOwl:hasNarrowSynonym "activation of nuclear mRNA splicing via U2-type spliceosome", "activation of nuclear mRNA splicing, via spliceosome", "positive regulation of nuclear mRNA splicing via U2-type spliceosome", "stimulation of nuclear mRNA splicing via U2-type spliceosome", "stimulation of nuclear mRNA splicing, via spliceosome", "up regulation of nuclear mRNA splicing via U2-type spliceosome", "up-regulation of nuclear mRNA splicing via U2-type spliceosome", "upregulation of nuclear mRNA splicing via U2-type spliceosome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048026" ; a owl:Class ; rdfs:label "positive regulation of mRNA splicing, via spliceosome" ; rdfs:subClassOf obo:GO_0033120, obo:GO_0048024, obo:GO_0050685, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000398 ] ) ] . obo:GO_0048066 obo:IAO_0000115 "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pigmentation during development" ; oboInOwl:id "GO:0048066" ; a owl:Class ; rdfs:label "developmental pigmentation" ; rdfs:subClassOf obo:GO_0043473 . obo:GO_0048070 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ; oboInOwl:hasExactSynonym "regulation of pigmentation during development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048070" ; a owl:Class ; rdfs:label "regulation of developmental pigmentation" ; rdfs:subClassOf obo:GO_0120305, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048066 ] ) ] . obo:GO_0048086 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ; oboInOwl:hasExactSynonym "down regulation of developmental pigmentation", "down-regulation of developmental pigmentation", "downregulation of developmental pigmentation" ; oboInOwl:hasNarrowSynonym "inhibition of pigmentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048086" ; a owl:Class ; rdfs:label "negative regulation of developmental pigmentation" ; rdfs:subClassOf obo:GO_0048070, obo:GO_0048519, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048066 ] ) ] . obo:GO_0048087 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism." ; oboInOwl:hasExactSynonym "up regulation of developmental pigmentation", "up-regulation of developmental pigmentation", "upregulation of developmental pigmentation" ; oboInOwl:hasNarrowSynonym "activation of developmental pigmentation", "stimulation of developmental pigmentation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048087" ; a owl:Class ; rdfs:label "positive regulation of developmental pigmentation" ; rdfs:subClassOf obo:GO_0048070, obo:GO_0048518, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048066 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048066 ] ) ] . obo:GO_0048102 obo:IAO_0000115 "A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells." ; oboInOwl:hasBroadSynonym "autophagic death", "programmed cell death by autophagy" ; oboInOwl:hasExactSynonym "programmed cell death by macroautophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "autosis", "type II programmed cell death" ; oboInOwl:id "GO:0048102" ; a owl:Class ; rdfs:comment "The precise nature of autophagic cell death is still being debated, and the link between autophagy and cell death unclear. As autophagy is often induced under conditions of stress that could also lead to cell death, there has been a propagation of the idea that autophagy can act as a cell death mechanism; but others suggest that autophagy may simply be an attempt of dying cells to adapt to lethal stress rather than a mechanism to execute a cell death program. Further studies are required to resolve this controversy (see e.g. PMID:22082964, PMID:22052193, PMID:25236395). In the meantime, curators should carefully examine the experimental evidence presented in papers concerning autophagic cell death, and annotate accordingly. Recently, an instance of autophagic cell death, termed autosis, was discovered that relies on the plasma membrane Na+/K+-ATPase. Autosis was observed in vivo in the brain of rats subjected to an ischemic insult. It's still unclear if all cases of autophagic cell death require the Na+/K+-ATPase or not." ; rdfs:label "autophagic cell death" ; rdfs:subClassOf obo:GO_0012501, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016236 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0012501 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0016236 ] ) ] . obo:GO_0048232 obo:IAO_0000115 "Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048232" ; a owl:Class ; rdfs:label "male gamete generation" ; rdfs:subClassOf obo:GO_0007276 . obo:GO_0048259 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." ; oboInOwl:hasExactSynonym "regulation of receptor mediated endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048259" ; a owl:Class ; rdfs:label "regulation of receptor-mediated endocytosis" ; rdfs:subClassOf obo:GO_0030100, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006898 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006898 ] ) ] . obo:GO_0048260 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." ; oboInOwl:hasExactSynonym "positive regulation of receptor mediated endocytosis", "up regulation of receptor mediated endocytosis", "up-regulation of receptor mediated endocytosis", "upregulation of receptor mediated endocytosis" ; oboInOwl:hasNarrowSynonym "activation of receptor mediated endocytosis", "stimulation of receptor mediated endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048260" ; a owl:Class ; rdfs:label "positive regulation of receptor-mediated endocytosis" ; rdfs:subClassOf obo:GO_0045807, obo:GO_0048259, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006898 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006898 ] ) ] . obo:GO_0048261 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport." ; oboInOwl:hasExactSynonym "down regulation of receptor mediated endocytosis", "down-regulation of receptor mediated endocytosis", "downregulation of receptor mediated endocytosis", "negative regulation of receptor mediated endocytosis" ; oboInOwl:hasNarrowSynonym "inhibition of receptor mediated endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048261" ; a owl:Class ; rdfs:label "negative regulation of receptor-mediated endocytosis" ; rdfs:subClassOf obo:GO_0045806, obo:GO_0048259, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006898 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006898 ] ) ] . obo:GO_0048284 obo:IAO_0000115 "The creation of a single organelle from two or more organelles." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048284" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "organelle fusion" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0048285 obo:IAO_0000115 "The creation of two or more organelles by division of one organelle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048285" ; oboInOwl:inSubset go:goslim_pir, go:goslim_yeast ; a owl:Class ; rdfs:label "organelle fission" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0048332 obo:IAO_0000115 "The process in which the anatomical structures of the mesoderm are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048332" ; a owl:Class ; rdfs:label "mesoderm morphogenesis" ; rdfs:subClassOf obo:GO_0048729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007498 ] . obo:GO_0048468 obo:IAO_0000115 "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "terminal differentiation" ; oboInOwl:id "GO:0048468" ; oboInOwl:inSubset go:goslim_candida ; a owl:Class ; rdfs:label "cell development" ; rdfs:subClassOf obo:GO_0048856, obo:GO_0048869, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030154 ] . obo:GO_0048469 obo:IAO_0000115 "The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "functional differentiation" ; oboInOwl:id "GO:0048469" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cell maturation" ; rdfs:subClassOf obo:GO_0048869, obo:GO_0071695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ] . obo:GO_0048477 obo:IAO_0000115 "The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster." ; oboInOwl:hasAlternativeId "GO:0009993", "GO:0048157" ; oboInOwl:hasDbXref "Wikipedia:Oogenesis" ; oboInOwl:hasExactSynonym "ovum development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048477" ; a owl:Class ; rdfs:label "oogenesis" ; rdfs:subClassOf obo:GO_0007281, obo:GO_0007292 . obo:GO_0048488 obo:IAO_0000115 "A vesicle-mediated transport process, in which the synaptic vesicle membrane constituents are retrieved from the presynaptic membrane on the axon terminal after neurotransmitter secretion by exocytosis. Synaptic vesicle endocytosis can occur via clathrin-dependent and clathrin-independent mechanisms." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/230"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0008099" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "synaptic vesicle retrieval" ; oboInOwl:id "GO:0048488" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle endocytosis" ; rdfs:subClassOf obo:GO_0140238, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0036465 ] . obo:GO_0048489 obo:IAO_0000115 "The directed movement of synaptic vesicles." ; oboInOwl:hasAlternativeId "GO:0016181" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "synaptic vesicle fission", "synaptic vesicle fusion", "synaptic vesicle trafficking" ; oboInOwl:id "GO:0048489" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle transport" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0009987, obo:GO_0051650, obo:GO_0097479 . obo:GO_0048490 obo:IAO_0000115 "The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse." ; oboInOwl:hasExactSynonym "anterograde axonal transport of synaptic vesicle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048490" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "anterograde synaptic vesicle transport" ; rdfs:subClassOf obo:GO_0008089, obo:GO_0099517 . obo:GO_0048511 obo:IAO_0000115 "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "rhythm" ; oboInOwl:id "GO:0048511" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "rhythmic process" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0048512 obo:IAO_0000115 "The specific behavior of an organism that recurs with a regularity of approximately 24 hours." ; oboInOwl:hasExactSynonym "circadian rhythm behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048512" ; a owl:Class ; rdfs:label "circadian behavior" ; rdfs:subClassOf obo:GO_0007622, obo:GO_0007623 . obo:GO_0048513 obo:IAO_0000115 "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25943"^^xsd:anyURI ; oboInOwl:hasDbXref "Wikipedia:Organogenesis" ; oboInOwl:hasExactSynonym "development of an organ", "organogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048513" ; a owl:Class ; rdfs:label "animal organ development" ; rdfs:subClassOf obo:GO_0048856 . obo:GO_0048515 obo:IAO_0000115 "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ; oboInOwl:hasExactSynonym "spermatid cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048515" ; a owl:Class ; rdfs:label "spermatid differentiation" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0022412, obo:GO_0030154, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007283 ] . obo:GO_0048518 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ; oboInOwl:hasAlternativeId "GO:0043119" ; oboInOwl:hasExactSynonym "positive regulation of physiological process", "up regulation of biological process", "up-regulation of biological process", "upregulation of biological process" ; oboInOwl:hasNarrowSynonym "activation of biological process", "stimulation of biological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048518" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of biological process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008150 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008150 ] ) ] . obo:GO_0048519 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ; oboInOwl:hasAlternativeId "GO:0043118" ; oboInOwl:hasExactSynonym "down regulation of biological process", "down-regulation of biological process", "downregulation of biological process", "negative regulation of physiological process" ; oboInOwl:hasNarrowSynonym "inhibition of biological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048519" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of biological process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008150 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008150 ] ) ] . obo:GO_0048520 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ; oboInOwl:hasExactSynonym "up regulation of behavior", "up-regulation of behavior", "upregulation of behavior" ; oboInOwl:hasNarrowSynonym "activation of behavior", "stimulation of behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048520" ; a owl:Class ; rdfs:label "positive regulation of behavior" ; rdfs:subClassOf obo:GO_0050795, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007610 ] ) ] . obo:GO_0048521 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ; oboInOwl:hasExactSynonym "down regulation of behavior", "down-regulation of behavior", "downregulation of behavior" ; oboInOwl:hasNarrowSynonym "inhibition of behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048521" ; a owl:Class ; rdfs:label "negative regulation of behavior" ; rdfs:subClassOf obo:GO_0050795, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007610 ] ) ] . obo:GO_0048522 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; oboInOwl:hasAlternativeId "GO:0051242" ; oboInOwl:hasExactSynonym "positive regulation of cellular physiological process", "up regulation of cellular process", "up-regulation of cellular process", "upregulation of cellular process" ; oboInOwl:hasNarrowSynonym "activation of cellular process", "stimulation of cellular process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048522" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of cellular process" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009987 ] ) ] . obo:GO_0048523 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; oboInOwl:hasAlternativeId "GO:0051243" ; oboInOwl:hasExactSynonym "down regulation of cellular process", "down-regulation of cellular process", "downregulation of cellular process", "negative regulation of cellular physiological process" ; oboInOwl:hasNarrowSynonym "inhibition of cellular process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048523" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of cellular process" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009987 ] ) ] . obo:GO_0048534 obo:IAO_0000115 "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation." ; oboInOwl:hasExactSynonym "haematopoietic or lymphoid organ development", "haemopoietic or lymphoid organ development", "hemopoietic or lymphoid organ development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048534" ; a owl:Class ; rdfs:label "hematopoietic or lymphoid organ development" ; rdfs:subClassOf obo:GO_0048513, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0002520 ] . obo:GO_0048540 obo:IAO_0000115 "The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048540" ; a owl:Class ; rdfs:label "bursa of Fabricius development" ; rdfs:subClassOf obo:GO_0048534 . obo:GO_0048565 obo:IAO_0000115 "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed." ; oboInOwl:hasBroadSynonym "gut development" ; oboInOwl:hasNarrowSynonym "intestinal development", "intestine development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048565" ; a owl:Class ; rdfs:label "digestive tract development" ; rdfs:subClassOf obo:GO_0035295, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0055123 ] . obo:GO_0048580 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048580" ; a owl:Class ; rdfs:label "regulation of post-embryonic development" ; rdfs:subClassOf obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009791 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009791 ] ) ] . obo:GO_0048581 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ; oboInOwl:hasExactSynonym "down regulation of post-embryonic development", "down-regulation of post-embryonic development", "downregulation of post-embryonic development" ; oboInOwl:hasNarrowSynonym "inhibition of post-embryonic development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048581" ; a owl:Class ; rdfs:label "negative regulation of post-embryonic development" ; rdfs:subClassOf obo:GO_0048580, obo:GO_0051093, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009791 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009791 ] ) ] . obo:GO_0048582 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure." ; oboInOwl:hasExactSynonym "up regulation of post-embryonic development", "up-regulation of post-embryonic development", "upregulation of post-embryonic development" ; oboInOwl:hasNarrowSynonym "activation of post-embryonic development", "stimulation of post-embryonic development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048582" ; a owl:Class ; rdfs:label "positive regulation of post-embryonic development" ; rdfs:subClassOf obo:GO_0048580, obo:GO_0051094, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009791 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009791 ] ) ] . obo:GO_0048583 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048583" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "regulation of response to stimulus" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050896 ] ) ] . obo:GO_0048584 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ; oboInOwl:hasExactSynonym "up regulation of response to stimulus", "up-regulation of response to stimulus", "upregulation of response to stimulus" ; oboInOwl:hasNarrowSynonym "activation of response to stimulus", "stimulation of response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048584" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "positive regulation of response to stimulus" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050896 ] ) ] . obo:GO_0048585 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus." ; oboInOwl:hasExactSynonym "down regulation of response to stimulus", "down-regulation of response to stimulus", "downregulation of response to stimulus" ; oboInOwl:hasNarrowSynonym "inhibition of response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048585" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "negative regulation of response to stimulus" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050896 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050896 ] ) ] . obo:GO_0048588 obo:IAO_0000115 "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another." ; oboInOwl:hasExactSynonym "developmental growth of a unicellular organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048588" ; a owl:Class ; rdfs:label "developmental cell growth" ; rdfs:subClassOf obo:GO_0016049, obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048468 ] . obo:GO_0048589 obo:IAO_0000115 "The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048589" ; a owl:Class ; rdfs:label "developmental growth" ; rdfs:subClassOf obo:GO_0040007, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0040007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032502 ] ) ] . obo:GO_0048598 obo:IAO_0000115 "The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants." ; oboInOwl:hasAlternativeId "GO:0048828" ; oboInOwl:hasExactSynonym "embryonic anatomical structure morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048598" ; a owl:Class ; rdfs:label "embryonic morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009790 ] . obo:GO_0048599 obo:IAO_0000115 "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048599" ; a owl:Class ; rdfs:label "oocyte development" ; rdfs:subClassOf obo:GO_0007281, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009994 ] . obo:GO_0048608 obo:IAO_0000115 "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23445"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048608" ; a owl:Class ; rdfs:label "reproductive structure development" ; rdfs:subClassOf obo:GO_0003006, obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0061458 ] . obo:GO_0048609 obo:IAO_0000115 "The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs." ; oboInOwl:hasBroadSynonym "organismal reproductive process" ; oboInOwl:hasExactSynonym "reproductive process in a multicellular organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048609" ; a owl:Class ; rdfs:label "multicellular organismal reproductive process" ; rdfs:subClassOf obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032504 ] . obo:GO_0048634 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of muscle development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048634" ; a owl:Class ; rdfs:label "regulation of muscle organ development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007517 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007517 ] ) ] . obo:GO_0048635 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development." ; oboInOwl:hasExactSynonym "down regulation of muscle development", "down-regulation of muscle development", "downregulation of muscle development" ; oboInOwl:hasNarrowSynonym "inhibition of muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048635" ; a owl:Class ; rdfs:label "negative regulation of muscle organ development" ; rdfs:subClassOf obo:GO_0048634, obo:GO_0051093, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007517 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007517 ] ) ] . obo:GO_0048636 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of muscle development." ; oboInOwl:hasExactSynonym "up regulation of muscle development", "up-regulation of muscle development", "upregulation of muscle development" ; oboInOwl:hasNarrowSynonym "activation of muscle development", "stimulation of muscle development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048636" ; a owl:Class ; rdfs:label "positive regulation of muscle organ development" ; rdfs:subClassOf obo:GO_0048634, obo:GO_0051094, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007517 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007517 ] ) ] . obo:GO_0048638 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of developmental growth." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048638" ; a owl:Class ; rdfs:label "regulation of developmental growth" ; rdfs:subClassOf obo:GO_0040008, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048589 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048589 ] ) ] . obo:GO_0048639 obo:IAO_0000115 "Any process that activates, maintains or increases the rate of developmental growth." ; oboInOwl:hasExactSynonym "up regulation of developmental growth", "up-regulation of developmental growth", "upregulation of developmental growth" ; oboInOwl:hasNarrowSynonym "activation of developmental growth", "stimulation of developmental growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048639" ; a owl:Class ; rdfs:label "positive regulation of developmental growth" ; rdfs:subClassOf obo:GO_0045927, obo:GO_0048638, obo:GO_0051094, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048589 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048589 ] ) ] . obo:GO_0048640 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth." ; oboInOwl:hasExactSynonym "down regulation of developmental growth", "down-regulation of developmental growth", "downregulation of developmental growth" ; oboInOwl:hasNarrowSynonym "inhibition of developmental growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048640" ; a owl:Class ; rdfs:label "negative regulation of developmental growth" ; rdfs:subClassOf obo:GO_0045926, obo:GO_0048638, obo:GO_0051093, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048589 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048589 ] ) ] . obo:GO_0048646 obo:IAO_0000115 "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ; oboInOwl:hasExactSynonym "formation of an anatomical structure involved in morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048646" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:comment "Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense." ; rdfs:label "anatomical structure formation involved in morphogenesis" ; rdfs:subClassOf obo:GO_0032502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] . obo:GO_0048666 obo:IAO_0000115 "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048666" ; a owl:Class ; rdfs:label "neuron development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030182 ] . obo:GO_0048667 obo:IAO_0000115 "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron." ; oboInOwl:hasExactSynonym "neuron morphogenesis involved in differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048667" ; a owl:Class ; rdfs:label "cell morphogenesis involved in neuron differentiation" ; rdfs:subClassOf obo:GO_0000902, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048666 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000902 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030182 ] ) ] . obo:GO_0048675 obo:IAO_0000115 "Long distance growth of a single axon process involved in cellular development." ; oboInOwl:hasAlternativeId "GO:0048676" ; oboInOwl:hasExactSynonym "axon extension involved in development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048675" ; a owl:Class ; rdfs:label "axon extension" ; rdfs:subClassOf obo:GO_1990138, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007409 ] . obo:GO_0048699 obo:IAO_0000115 "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons." ; oboInOwl:hasExactSynonym "neuron generation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048699" ; a owl:Class ; rdfs:label "generation of neurons" ; rdfs:subClassOf obo:GO_0022008 . obo:GO_0048729 obo:IAO_0000115 "The process in which the anatomical structures of a tissue are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048729" ; a owl:Class ; rdfs:label "tissue morphogenesis" ; rdfs:subClassOf obo:GO_0009653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009888 ] . obo:GO_0048731 obo:IAO_0000115 "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048731" ; oboInOwl:inSubset go:goslim_mouse ; a owl:Class ; rdfs:label "system development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007275 ] . obo:GO_0048786 obo:IAO_0000115 "A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix." ; oboInOwl:hasDbXref "NIF_Subcellular:sao792027222" ; oboInOwl:hasExactSynonym "pre-synaptic active zone", "presynaptic specialization" ; oboInOwl:hasNarrowSynonym "pre-synaptic active zone component" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0048786" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic active zone" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] . obo:GO_0048812 obo:IAO_0000115 "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites." ; oboInOwl:hasNarrowSynonym "neurite biosynthesis", "neurite formation", "neurite growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "neurite morphogenesis" ; oboInOwl:id "GO:0048812" ; a owl:Class ; rdfs:label "neuron projection morphogenesis" ; rdfs:subClassOf obo:GO_0120039, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0031175 ] . obo:GO_0048841 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048841" ; a owl:Class ; rdfs:label "regulation of axon extension involved in axon guidance" ; rdfs:subClassOf obo:GO_0030516, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048846 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048846 ] ) ] . obo:GO_0048842 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance." ; oboInOwl:hasExactSynonym "up regulation of axon extension involved in axon guidance", "up-regulation of axon extension involved in axon guidance", "upregulation of axon extension involved in axon guidance" ; oboInOwl:hasNarrowSynonym "activation of axon extension involved in axon guidance", "stimulation of axon extension involved in axon guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048842" ; a owl:Class ; rdfs:label "positive regulation of axon extension involved in axon guidance" ; rdfs:subClassOf obo:GO_0045773, obo:GO_0048841, obo:GO_0050921, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048846 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048846 ] ) ] . obo:GO_0048843 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance." ; oboInOwl:hasExactSynonym "down regulation of axon extension involved in axon guidance", "down-regulation of axon extension involved in axon guidance", "downregulation of axon extension involved in axon guidance" ; oboInOwl:hasNarrowSynonym "inhibition of axon extension involved in axon guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048843" ; a owl:Class ; rdfs:label "negative regulation of axon extension involved in axon guidance" ; rdfs:subClassOf obo:GO_0030517, obo:GO_0048841, obo:GO_0050922, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048846 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048846 ] ) ] . obo:GO_0048846 obo:IAO_0000115 "The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048846" ; a owl:Class ; rdfs:label "axon extension involved in axon guidance" ; rdfs:subClassOf obo:GO_0048675, obo:GO_1902284, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048675 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ] ) ] . obo:GO_0048856 obo:IAO_0000115 "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome." ; oboInOwl:hasExactSynonym "development of an anatomical structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048856" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic, go:goslim_plant ; a owl:Class ; rdfs:label "anatomical structure development" ; rdfs:subClassOf obo:GO_0032502 . obo:GO_0048858 obo:IAO_0000115 "The process in which the anatomical structures of a cell projection are generated and organized." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048858" ; a owl:Class ; rdfs:label "cell projection morphogenesis" ; rdfs:subClassOf obo:GO_0030030, obo:GO_0032989, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000902 ] . obo:GO_0048869 obo:IAO_0000115 "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048869" ; a owl:Class ; rdfs:label "cellular developmental process" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0032502 . obo:GO_0048870 obo:IAO_0000115 "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI ; oboInOwl:hasExactSynonym "cell locomotion", "movement of a cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell movement" ; oboInOwl:id "GO:0048870" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "cell motility" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0048878 obo:IAO_0000115 "Any biological process involved in the maintenance of an internal steady state of a chemical." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048878" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "chemical homeostasis" ; rdfs:subClassOf obo:GO_0042592 . obo:GO_0048880 obo:IAO_0000115 "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0048880" ; a owl:Class ; rdfs:label "sensory system development" ; rdfs:subClassOf obo:GO_0048731 . obo:GO_0050000 obo:IAO_0000115 "Any process in which a chromosome is transported to, or maintained in, a specific location." ; oboInOwl:hasExactSynonym "chromosome localisation", "establishment and maintenance of chromosome localization", "establishment and maintenance of chromosome position" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050000" ; a owl:Class ; rdfs:label "chromosome localization" ; rdfs:subClassOf obo:GO_0051640 . obo:GO_0050657 obo:IAO_0000115 "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050657" ; a owl:Class ; rdfs:label "nucleic acid transport" ; rdfs:subClassOf obo:GO_0015931 . obo:GO_0050658 obo:IAO_0000115 "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050658" ; a owl:Class ; rdfs:label "RNA transport" ; rdfs:subClassOf obo:GO_0050657, obo:GO_0051236 . obo:GO_0050684 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050684" ; a owl:Class ; rdfs:label "regulation of mRNA processing" ; rdfs:subClassOf obo:GO_1903311, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006397 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006397 ] ) ] . obo:GO_0050685 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mRNA processing." ; oboInOwl:hasExactSynonym "up regulation of mRNA processing", "up-regulation of mRNA processing", "upregulation of mRNA processing" ; oboInOwl:hasNarrowSynonym "activation of mRNA processing", "stimulation of mRNA processing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050685" ; a owl:Class ; rdfs:label "positive regulation of mRNA processing" ; rdfs:subClassOf obo:GO_0050684, obo:GO_1903313, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006397 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006397 ] ) ] . obo:GO_0050686 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing." ; oboInOwl:hasExactSynonym "down regulation of mRNA processing", "down-regulation of mRNA processing", "downregulation of mRNA processing" ; oboInOwl:hasNarrowSynonym "inhibition of mRNA processing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050686" ; a owl:Class ; rdfs:label "negative regulation of mRNA processing" ; rdfs:subClassOf obo:GO_0050684, obo:GO_1903312, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006397 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006397 ] ) ] . obo:GO_0050708 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050708" ; a owl:Class ; rdfs:label "regulation of protein secretion" ; rdfs:subClassOf obo:GO_0051223, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009306 ] ) ] . obo:GO_0050709 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell." ; oboInOwl:hasExactSynonym "down regulation of protein secretion", "down-regulation of protein secretion", "downregulation of protein secretion" ; oboInOwl:hasNarrowSynonym "inhibition of protein secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050709" ; a owl:Class ; rdfs:label "negative regulation of protein secretion" ; rdfs:subClassOf obo:GO_0050708, obo:GO_0051224, obo:GO_1903531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009306 ] ) ] . obo:GO_0050714 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell." ; oboInOwl:hasExactSynonym "up regulation of protein secretion", "up-regulation of protein secretion", "upregulation of protein secretion" ; oboInOwl:hasNarrowSynonym "activation of protein secretion", "stimulation of protein secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050714" ; a owl:Class ; rdfs:label "positive regulation of protein secretion" ; rdfs:subClassOf obo:GO_0050708, obo:GO_0051222, obo:GO_1903532, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009306 ] ) ] . obo:GO_0050764 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material." ; obo:RO_0002161 obo:NCBITaxon_147537 ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050764" ; a owl:Class ; rdfs:label "regulation of phagocytosis" ; rdfs:subClassOf obo:GO_0030100, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0050765 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis." ; oboInOwl:hasExactSynonym "down regulation of phagocytosis", "down-regulation of phagocytosis", "downregulation of phagocytosis" ; oboInOwl:hasNarrowSynonym "inhibition of phagocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050765" ; a owl:Class ; rdfs:label "negative regulation of phagocytosis" ; rdfs:subClassOf obo:GO_0045806, obo:GO_0050764, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0050766 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of phagocytosis." ; oboInOwl:hasExactSynonym "up regulation of phagocytosis", "up-regulation of phagocytosis", "upregulation of phagocytosis" ; oboInOwl:hasNarrowSynonym "activation of phagocytosis", "stimulation of phagocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050766" ; a owl:Class ; rdfs:label "positive regulation of phagocytosis" ; rdfs:subClassOf obo:GO_0045807, obo:GO_0050764, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006909 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006909 ] ) ] . obo:GO_0050767 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050767" ; a owl:Class ; rdfs:label "regulation of neurogenesis" ; rdfs:subClassOf obo:GO_0051960, obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022008 ] ) ] . obo:GO_0050768 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." ; oboInOwl:hasExactSynonym "down regulation of neurogenesis", "down-regulation of neurogenesis", "downregulation of neurogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of neurogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050768" ; a owl:Class ; rdfs:label "negative regulation of neurogenesis" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0050767, obo:GO_0051961, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022008 ] ) ] . obo:GO_0050769 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system." ; oboInOwl:hasExactSynonym "up regulation of neurogenesis", "up-regulation of neurogenesis", "upregulation of neurogenesis" ; oboInOwl:hasNarrowSynonym "activation of neurogenesis", "stimulation of neurogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050769" ; a owl:Class ; rdfs:label "positive regulation of neurogenesis" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0050767, obo:GO_0051962, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022008 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022008 ] ) ] . obo:GO_0050770 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050770" ; a owl:Class ; rdfs:label "regulation of axonogenesis" ; rdfs:subClassOf obo:GO_0010975, obo:GO_0022603, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007409 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007409 ] ) ] . obo:GO_0050771 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis." ; oboInOwl:hasExactSynonym "down regulation of axonogenesis", "down-regulation of axonogenesis", "downregulation of axonogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of axonogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050771" ; a owl:Class ; rdfs:label "negative regulation of axonogenesis" ; rdfs:subClassOf obo:GO_0010977, obo:GO_0050768, obo:GO_0050770, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007409 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007409 ] ) ] . obo:GO_0050772 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of axonogenesis." ; oboInOwl:hasExactSynonym "up regulation of axonogenesis", "up-regulation of axonogenesis", "upregulation of axonogenesis" ; oboInOwl:hasNarrowSynonym "activation of axonogenesis", "stimulation of axonogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050772" ; a owl:Class ; rdfs:label "positive regulation of axonogenesis" ; rdfs:subClassOf obo:GO_0031346, obo:GO_0050769, obo:GO_0050770, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007409 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007409 ] ) ] . obo:GO_0050773 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of dendrite development." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050773" ; a owl:Class ; rdfs:label "regulation of dendrite development" ; rdfs:subClassOf obo:GO_0010975, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016358 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016358 ] ) ] . obo:GO_0050776 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050776" ; a owl:Class ; rdfs:label "regulation of immune response" ; rdfs:subClassOf obo:GO_0002682, obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0050777 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ; oboInOwl:hasExactSynonym "down regulation of immune response", "down-regulation of immune response", "downregulation of immune response" ; oboInOwl:hasNarrowSynonym "inhibition of immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050777" ; a owl:Class ; rdfs:label "negative regulation of immune response" ; rdfs:subClassOf obo:GO_0002683, obo:GO_0048585, obo:GO_0050776, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0050778 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus." ; oboInOwl:hasExactSynonym "up regulation of immune response", "up-regulation of immune response", "upregulation of immune response" ; oboInOwl:hasNarrowSynonym "stimulation of immune response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050778" ; a owl:Class ; rdfs:label "positive regulation of immune response" ; rdfs:subClassOf obo:GO_0002684, obo:GO_0048584, obo:GO_0050776, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006955 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006955 ] ) ] . obo:GO_0050789 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule." ; oboInOwl:hasAlternativeId "GO:0050791" ; oboInOwl:hasExactSynonym "regulation of physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050789" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_candida, go:goslim_pir ; a owl:Class ; rdfs:label "regulation of biological process" ; rdfs:subClassOf obo:BFO_0000015, obo:GO_0065007, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008150 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008150 ] ) ] . obo:GO_0050790 obo:IAO_0000115 "Any process that modulates the activity of an enzyme." ; oboInOwl:hasAlternativeId "GO:0048552" ; oboInOwl:hasExactSynonym "regulation of enzyme activity" ; oboInOwl:hasNarrowSynonym "regulation of metalloenzyme activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050790" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_chembl ; a owl:Class ; rdfs:label "regulation of catalytic activity" ; rdfs:subClassOf obo:GO_0065009, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003824 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003824 ] ) ] . obo:GO_0050793 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050793" ; a owl:Class ; rdfs:label "regulation of developmental process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032502 ] ) ] . obo:GO_0050794 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level." ; oboInOwl:hasAlternativeId "GO:0051244" ; oboInOwl:hasExactSynonym "regulation of cellular physiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050794" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "regulation of cellular process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009987 ] ) ] . obo:GO_0050795 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli." ; oboInOwl:hasExactSynonym "regulation of behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050795" ; a owl:Class ; rdfs:label "regulation of behavior" ; rdfs:subClassOf obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007610 ] ) ] . obo:GO_0050801 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:2000021" ; oboInOwl:hasBroadSynonym "ion homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "electrolyte homeostasis", "negative regulation of crystal formation", "regulation of ion homeostasis" ; oboInOwl:id "GO:0050801" ; a owl:Class ; rdfs:label "monoatomic ion homeostasis" ; rdfs:subClassOf obo:GO_0048878 . obo:GO_0050803 obo:IAO_0000115 "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050803" ; a owl:Class ; rdfs:label "regulation of synapse structure or activity" ; rdfs:subClassOf obo:GO_0065008 . obo:GO_0050804 obo:IAO_0000115 "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission." ; oboInOwl:hasBroadSynonym "modulation of synaptic transmission" ; oboInOwl:hasExactSynonym "regulation of chemical synaptic transmission", "regulation of synaptic transmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050804" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "modulation of chemical synaptic transmission" ; rdfs:subClassOf obo:GO_0099177, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0050805 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." ; oboInOwl:hasExactSynonym "down regulation of synaptic transmission", "down-regulation of synaptic transmission", "downregulation of synaptic transmission" ; oboInOwl:hasNarrowSynonym "inhibition of synaptic transmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050805" ; a owl:Class ; rdfs:label "negative regulation of synaptic transmission" ; rdfs:subClassOf obo:GO_0010648, obo:GO_0023057, obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007268 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0050806 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse." ; oboInOwl:hasExactSynonym "up regulation of synaptic transmission", "up-regulation of synaptic transmission", "upregulation of synaptic transmission" ; oboInOwl:hasNarrowSynonym "activation of synaptic transmission", "stimulation of synaptic transmission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050806" ; a owl:Class ; rdfs:label "positive regulation of synaptic transmission" ; rdfs:subClassOf obo:GO_0010647, obo:GO_0023056, obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007268 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0050807 obo:IAO_0000115 "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ; oboInOwl:hasExactSynonym "regulation of synapse organisation", "regulation of synapse structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of synapse organization and biogenesis" ; oboInOwl:id "GO:0050807" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of synapse organization" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0050803 ], [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050808 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050808 ] ) ] . obo:GO_0050808 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell)." ; oboInOwl:hasExactSynonym "synapse organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "synapse development", "synapse morphogenesis", "synapse organization and biogenesis" ; oboInOwl:id "GO:0050808" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_synapse ; a owl:Class ; rdfs:label "synapse organization" ; rdfs:subClassOf obo:GO_0034330 . obo:GO_0050821 obo:IAO_0000115 "Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation." ; oboInOwl:hasExactSynonym "positive regulation of protein stability", "protein stabilisation" ; oboInOwl:hasNarrowSynonym "lysosomal protein stabilization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein sequestering", "protein stabilization activity" ; oboInOwl:id "GO:0050821" ; oboInOwl:inSubset go:goslim_chembl ; a owl:Class ; rdfs:label "protein stabilization" ; rdfs:subClassOf obo:GO_0031647 . obo:GO_0050839 obo:IAO_0000115 "Binding to a cell adhesion molecule." ; oboInOwl:hasExactSynonym "CAM binding" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "adhesive extracellular matrix constituent", "cell adhesion molecule activity", "cell adhesion receptor activity" ; oboInOwl:id "GO:0050839" ; a owl:Class ; rdfs:label "cell adhesion molecule binding" ; rdfs:subClassOf obo:GO_0005515 . obo:GO_0050848 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response." ; oboInOwl:hasExactSynonym "regulation of calcium-mediated signalling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050848" ; a owl:Class ; rdfs:label "regulation of calcium-mediated signaling" ; rdfs:subClassOf obo:GO_1902531, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019722 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019722 ] ) ] . obo:GO_0050849 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling." ; oboInOwl:hasExactSynonym "down regulation of calcium-mediated signaling", "down-regulation of calcium-mediated signaling", "downregulation of calcium-mediated signaling", "negative regulation of calcium-mediated signalling" ; oboInOwl:hasNarrowSynonym "inhibition of calcium-mediated signaling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050849" ; a owl:Class ; rdfs:label "negative regulation of calcium-mediated signaling" ; rdfs:subClassOf obo:GO_0050848, obo:GO_1902532, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019722 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019722 ] ) ] . obo:GO_0050850 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling." ; oboInOwl:hasExactSynonym "positive regulation of calcium-mediated signalling", "up regulation of calcium-mediated signaling", "up-regulation of calcium-mediated signaling", "upregulation of calcium-mediated signaling" ; oboInOwl:hasNarrowSynonym "activation of calcium-mediated signaling", "stimulation of calcium-mediated signaling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050850" ; a owl:Class ; rdfs:label "positive regulation of calcium-mediated signaling" ; rdfs:subClassOf obo:GO_0050848, obo:GO_1902533, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019722 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019722 ] ) ] . obo:GO_0050877 obo:IAO_0000115 "A organ system process carried out by any of the organs or tissues of neurological system." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13824"^^xsd:anyURI ; oboInOwl:hasExactSynonym "neurological system process", "neurophysiological process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pan-neural process" ; oboInOwl:id "GO:0050877" ; oboInOwl:inSubset go:goslim_agr, go:goslim_chembl, go:goslim_flybase_ribbon, go:goslim_generic, go:goslim_pir ; a owl:Class ; rdfs:label "nervous system process" ; rdfs:subClassOf obo:GO_0003008 . obo:GO_0050890 obo:IAO_0000115 "The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory." ; oboInOwl:hasDbXref "Wikipedia:Cognition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050890" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "cognition" ; rdfs:subClassOf obo:GO_0050877 . obo:GO_0050896 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism." ; oboInOwl:hasAlternativeId "GO:0051869" ; oboInOwl:hasExactSynonym "physiological response to stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050896" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate, go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "response to stimulus" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0050918 obo:IAO_0000115 "The directed movement of a motile cell or organism towards a higher concentration of a chemical." ; oboInOwl:hasExactSynonym "chemoattraction" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050918" ; a owl:Class ; rdfs:label "positive chemotaxis" ; rdfs:subClassOf obo:GO_0006935 . obo:GO_0050919 obo:IAO_0000115 "The directed movement of a motile cell or organism towards a lower concentration of a chemical." ; oboInOwl:hasExactSynonym "chemoaversion", "chemorepulsion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050919" ; a owl:Class ; rdfs:label "negative chemotaxis" ; rdfs:subClassOf obo:GO_0006935 . obo:GO_0050920 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050920" ; a owl:Class ; rdfs:label "regulation of chemotaxis" ; rdfs:subClassOf obo:GO_0032101, obo:GO_0040012, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006935 ] ) ] . obo:GO_0050921 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ; oboInOwl:hasExactSynonym "up regulation of chemotaxis", "up-regulation of chemotaxis", "upregulation of chemotaxis" ; oboInOwl:hasNarrowSynonym "activation of chemotaxis", "stimulation of chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050921" ; a owl:Class ; rdfs:label "positive regulation of chemotaxis" ; rdfs:subClassOf obo:GO_0032103, obo:GO_0040017, obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006935 ] ) ] . obo:GO_0050922 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient." ; oboInOwl:hasExactSynonym "down regulation of chemotaxis", "down-regulation of chemotaxis", "downregulation of chemotaxis" ; oboInOwl:hasNarrowSynonym "inhibition of chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050922" ; a owl:Class ; rdfs:label "negative regulation of chemotaxis" ; rdfs:subClassOf obo:GO_0032102, obo:GO_0040013, obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006935 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006935 ] ) ] . obo:GO_0050923 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050923" ; a owl:Class ; rdfs:label "regulation of negative chemotaxis" ; rdfs:subClassOf obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050919 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050919 ] ) ] . obo:GO_0050924 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasExactSynonym "up regulation of negative chemotaxis", "up-regulation of negative chemotaxis", "upregulation of negative chemotaxis" ; oboInOwl:hasNarrowSynonym "activation of negative chemotaxis", "stimulation of negative chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050924" ; a owl:Class ; rdfs:label "positive regulation of negative chemotaxis" ; rdfs:subClassOf obo:GO_0050921, obo:GO_0050923, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050919 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050919 ] ) ] . obo:GO_0050925 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasExactSynonym "down regulation of negative chemotaxis", "down-regulation of negative chemotaxis", "downregulation of negative chemotaxis" ; oboInOwl:hasNarrowSynonym "inhibition of negative chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050925" ; a owl:Class ; rdfs:label "negative regulation of negative chemotaxis" ; rdfs:subClassOf obo:GO_0050922, obo:GO_0050923, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050919 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050919 ] ) ] . obo:GO_0050926 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050926" ; a owl:Class ; rdfs:label "regulation of positive chemotaxis" ; rdfs:subClassOf obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050918 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0050918 ] ) ] . obo:GO_0050927 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasExactSynonym "up regulation of positive chemotaxis", "up-regulation of positive chemotaxis", "upregulation of positive chemotaxis" ; oboInOwl:hasNarrowSynonym "activation of positive chemotaxis", "stimulation of positive chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050927" ; a owl:Class ; rdfs:label "positive regulation of positive chemotaxis" ; rdfs:subClassOf obo:GO_0050921, obo:GO_0050926, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050918 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0050918 ] ) ] . obo:GO_0050928 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical." ; oboInOwl:hasExactSynonym "down regulation of positive chemotaxis", "down-regulation of positive chemotaxis", "downregulation of positive chemotaxis" ; oboInOwl:hasNarrowSynonym "inhibition of positive chemotaxis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0050928" ; a owl:Class ; rdfs:label "negative regulation of positive chemotaxis" ; rdfs:subClassOf obo:GO_0050922, obo:GO_0050926, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050918 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050918 ] ) ] . obo:GO_0051028 obo:IAO_0000115 "The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051028" ; a owl:Class ; rdfs:label "mRNA transport" ; rdfs:subClassOf obo:GO_0050658 . obo:GO_0051046 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051046" ; a owl:Class ; rdfs:label "regulation of secretion" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046903 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0046903 ] ) ] . obo:GO_0051047 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ; oboInOwl:hasExactSynonym "up regulation of secretion", "up-regulation of secretion", "upregulation of secretion" ; oboInOwl:hasNarrowSynonym "activation of secretion", "stimulation of secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051047" ; a owl:Class ; rdfs:label "positive regulation of secretion" ; rdfs:subClassOf obo:GO_0051046, obo:GO_0051050, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046903 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0046903 ] ) ] . obo:GO_0051048 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue." ; oboInOwl:hasExactSynonym "down regulation of secretion", "down-regulation of secretion", "downregulation of secretion" ; oboInOwl:hasNarrowSynonym "inhibition of secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051048" ; a owl:Class ; rdfs:label "negative regulation of secretion" ; rdfs:subClassOf obo:GO_0051046, obo:GO_0051051, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046903 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0046903 ] ) ] . obo:GO_0051049 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051049" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of transport" ; rdfs:subClassOf obo:GO_0032879, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006810 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006810 ] ) ] . obo:GO_0051050 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of transport", "up-regulation of transport", "upregulation of transport" ; oboInOwl:hasNarrowSynonym "activation of transport", "stimulation of transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051050" ; a owl:Class ; rdfs:label "positive regulation of transport" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006810 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006810 ] ) ] . obo:GO_0051051 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of transport", "down-regulation of transport", "downregulation of transport" ; oboInOwl:hasNarrowSynonym "inhibition of transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051051" ; a owl:Class ; rdfs:label "negative regulation of transport" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006810 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006810 ] ) ] . obo:GO_0051052 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA." ; oboInOwl:hasExactSynonym "regulation of DNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051052" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of DNA metabolic process" ; rdfs:subClassOf obo:GO_0019219, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006259 ] ) ] . obo:GO_0051053 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA." ; oboInOwl:hasExactSynonym "down regulation of DNA metabolic process", "down-regulation of DNA metabolic process", "downregulation of DNA metabolic process", "negative regulation of DNA metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of DNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051053" ; a owl:Class ; rdfs:label "negative regulation of DNA metabolic process" ; rdfs:subClassOf obo:GO_0010605, obo:GO_0045934, obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006259 ] ) ] . obo:GO_0051054 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA." ; oboInOwl:hasExactSynonym "positive regulation of DNA metabolism", "up regulation of DNA metabolic process", "up-regulation of DNA metabolic process", "upregulation of DNA metabolic process" ; oboInOwl:hasNarrowSynonym "activation of DNA metabolic process", "stimulation of DNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051054" ; a owl:Class ; rdfs:label "positive regulation of DNA metabolic process" ; rdfs:subClassOf obo:GO_0010604, obo:GO_0045935, obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006259 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006259 ] ) ] . obo:GO_0051055 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids." ; oboInOwl:hasExactSynonym "down regulation of lipid biosynthetic process", "down-regulation of lipid biosynthetic process", "downregulation of lipid biosynthetic process", "negative regulation of lipid anabolism", "negative regulation of lipid biosynthesis", "negative regulation of lipid formation", "negative regulation of lipid synthesis", "negative regulation of lipogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of lipid biosynthetic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051055" ; a owl:Class ; rdfs:label "negative regulation of lipid biosynthetic process" ; rdfs:subClassOf obo:GO_0009890, obo:GO_0045833, obo:GO_0046890, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008610 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008610 ] ) ] . obo:GO_0051078 obo:IAO_0000115 "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiotic nuclear envelope breakdown", "meiotic nuclear envelope catabolism", "meiotic nuclear envelope degradation", "meiotic nuclear envelope disassembly" ; oboInOwl:id "GO:0051078" ; a owl:Class ; rdfs:label "meiotic nuclear membrane disassembly" ; rdfs:subClassOf obo:GO_0051081, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051081 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051079 obo:IAO_0000115 "The controlled breakdown of the nuclear membranes during the first division of meiosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiosis I nuclear envelope breakdown", "meiosis I nuclear envelope catabolism", "meiosis I nuclear envelope degradation", "meiosis I nuclear envelope disassembly" ; oboInOwl:id "GO:0051079" ; a owl:Class ; rdfs:label "meiosis I nuclear membrane disassembly" ; rdfs:subClassOf obo:GO_0051078, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051081 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0051081 obo:IAO_0000115 "The controlled breakdown of the nuclear membranes, for example during cellular division." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear envelope breakdown", "nuclear envelope catabolism", "nuclear envelope degradation", "nuclear envelope disassembly" ; oboInOwl:id "GO:0051081" ; a owl:Class ; rdfs:label "nuclear membrane disassembly" ; rdfs:subClassOf obo:GO_0030397, obo:GO_0071763 . obo:GO_0051093 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ; oboInOwl:hasExactSynonym "down regulation of developmental process", "down-regulation of developmental process", "downregulation of developmental process" ; oboInOwl:hasNarrowSynonym "inhibition of developmental process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051093" ; a owl:Class ; rdfs:label "negative regulation of developmental process" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032502 ] ) ] . obo:GO_0051094 obo:IAO_0000115 "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult)." ; oboInOwl:hasExactSynonym "up regulation of developmental process", "up-regulation of developmental process", "upregulation of developmental process" ; oboInOwl:hasNarrowSynonym "activation of developmental process", "stimulation of developmental process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051094" ; a owl:Class ; rdfs:label "positive regulation of developmental process" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032502 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032502 ] ) ] . obo:GO_0051098 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051098" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "regulation of binding" ; rdfs:subClassOf obo:GO_0065009, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005488 ] ) ] . obo:GO_0051099 obo:IAO_0000115 "Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ; oboInOwl:hasExactSynonym "up regulation of binding", "up-regulation of binding", "upregulation of binding" ; oboInOwl:hasNarrowSynonym "activation of binding", "stimulation of binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051099" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of binding" ; rdfs:subClassOf obo:GO_0044093, obo:GO_0051098, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005488 ] ) ] . obo:GO_0051100 obo:IAO_0000115 "Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule." ; oboInOwl:hasExactSynonym "down regulation of binding", "down-regulation of binding", "downregulation of binding" ; oboInOwl:hasNarrowSynonym "inhibition of binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051100" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of binding" ; rdfs:subClassOf obo:GO_0044092, obo:GO_0051098, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005488 ] ) ] . obo:GO_0051128 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; oboInOwl:hasExactSynonym "regulation of cellular component organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cell organisation", "regulation of cell organization", "regulation of cellular component organization and biogenesis" ; oboInOwl:id "GO:0051128" ; a owl:Class ; rdfs:label "regulation of cellular component organization" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016043 ] ) ] . obo:GO_0051129 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; oboInOwl:hasExactSynonym "down regulation of cell organization", "down-regulation of cell organization", "downregulation of cell organization" ; oboInOwl:hasNarrowSynonym "inhibition of cell organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell organisation", "negative regulation of cellular component organization and biogenesis" ; oboInOwl:id "GO:0051129" ; a owl:Class ; rdfs:label "negative regulation of cellular component organization" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016043 ] ) ] . obo:GO_0051130 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; oboInOwl:hasExactSynonym "positive regulation of cell organisation", "up regulation of cell organization", "up-regulation of cell organization", "upregulation of cell organization" ; oboInOwl:hasNarrowSynonym "activation of cell organization", "stimulation of cell organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cellular component organization and biogenesis" ; oboInOwl:id "GO:0051130" ; a owl:Class ; rdfs:label "positive regulation of cellular component organization" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016043 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016043 ] ) ] . obo:GO_0051147 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of muscle cell differentiation." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051147" ; a owl:Class ; rdfs:label "regulation of muscle cell differentiation" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042692 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042692 ] ) ] . obo:GO_0051148 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation." ; oboInOwl:hasExactSynonym "down regulation of muscle cell differentiation", "down-regulation of muscle cell differentiation", "downregulation of muscle cell differentiation" ; oboInOwl:hasNarrowSynonym "inhibition of muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051148" ; a owl:Class ; rdfs:label "negative regulation of muscle cell differentiation" ; rdfs:subClassOf obo:GO_0045596, obo:GO_0051147, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042692 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042692 ] ) ] . obo:GO_0051149 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation." ; oboInOwl:hasExactSynonym "up regulation of muscle cell differentiation", "up-regulation of muscle cell differentiation", "upregulation of muscle cell differentiation" ; oboInOwl:hasNarrowSynonym "activation of muscle cell differentiation", "stimulation of muscle cell differentiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051149" ; a owl:Class ; rdfs:label "positive regulation of muscle cell differentiation" ; rdfs:subClassOf obo:GO_0045597, obo:GO_0051147, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042692 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042692 ] ) ] . obo:GO_0051168 obo:IAO_0000115 "The directed movement of substances out of the nucleus." ; oboInOwl:hasExactSynonym "export from nucleus", "nucleus export", "substance nuclear export" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051168" ; a owl:Class ; rdfs:label "nuclear export" ; rdfs:subClassOf obo:GO_0006913 . obo:GO_0051169 obo:IAO_0000115 "The directed movement of substances into, out of, or within the nucleus." ; oboInOwl:hasDbXref "Wikipedia:Nuclear_transport" ; oboInOwl:hasExactSynonym "nucleus transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051169" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "nuclear transport" ; rdfs:subClassOf obo:GO_0046907 . obo:GO_0051170 obo:IAO_0000115 "The directed movement of substances into the nucleus." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-19T15:26:34Z" ; oboInOwl:hasAlternativeId "GO:1902593" ; oboInOwl:hasExactSynonym "nuclear import", "nuclear translocation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051170" ; a owl:Class ; rdfs:label "import into nucleus" ; rdfs:subClassOf obo:GO_0006913 . obo:GO_0051171 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." ; oboInOwl:hasExactSynonym "regulation of nitrogen metabolic process", "regulation of nitrogen metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051171" ; a owl:Class ; rdfs:label "regulation of nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006807 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006807 ] ) ] . obo:GO_0051172 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." ; oboInOwl:hasExactSynonym "down regulation of nitrogen metabolic process", "down-regulation of nitrogen metabolic process", "downregulation of nitrogen metabolic process", "negative regulation of nitrogen metabolic process", "negative regulation of nitrogen metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of nitrogen metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051172" ; a owl:Class ; rdfs:label "negative regulation of nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0051171, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006807 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006807 ] ) ] . obo:GO_0051173 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds." ; oboInOwl:hasExactSynonym "positive regulation of nitrogen metabolic process", "positive regulation of nitrogen metabolism", "up regulation of nitrogen metabolic process", "up-regulation of nitrogen metabolic process", "upregulation of nitrogen metabolic process" ; oboInOwl:hasNarrowSynonym "activation of nitrogen metabolic process", "stimulation of nitrogen metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051173" ; a owl:Class ; rdfs:label "positive regulation of nitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0051171, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006807 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006807 ] ) ] . obo:GO_0051174 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus." ; oboInOwl:hasExactSynonym "regulation of phosphorus metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051174" ; a owl:Class ; rdfs:label "regulation of phosphorus metabolic process" ; rdfs:subClassOf obo:GO_0031323, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006793 ] ) ] . obo:GO_0051179 obo:IAO_0000115 "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-18T13:51:04Z" ; oboInOwl:hasAlternativeId "GO:1902578" ; oboInOwl:hasExactSynonym "establishment and maintenance of localization", "establishment and maintenance of position", "localisation" ; oboInOwl:hasNarrowSynonym "establishment and maintenance of cellular component location", "establishment and maintenance of substance location", "establishment and maintenance of substrate location" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organism localization", "single-organism localization" ; oboInOwl:id "GO:0051179" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "localization" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0051222 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of protein transport", "up-regulation of protein transport", "upregulation of protein transport" ; oboInOwl:hasNarrowSynonym "activation of protein transport", "stimulation of protein transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051222" ; a owl:Class ; rdfs:label "positive regulation of protein transport" ; rdfs:subClassOf obo:GO_0051050, obo:GO_0051223, obo:GO_1904951, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0015031 ] ) ] . obo:GO_0051223 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051223" ; a owl:Class ; rdfs:label "regulation of protein transport" ; rdfs:subClassOf obo:GO_0051049, obo:GO_0070201, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0015031 ] ) ] . obo:GO_0051224 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of protein transport", "down-regulation of protein transport", "downregulation of protein transport" ; oboInOwl:hasNarrowSynonym "inhibition of protein transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051224" ; a owl:Class ; rdfs:label "negative regulation of protein transport" ; rdfs:subClassOf obo:GO_0051051, obo:GO_0051223, obo:GO_1904950, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0015031 ] ) ] . obo:GO_0051225 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24375"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0051226", "GO:0051227" ; oboInOwl:hasExactSynonym "bipolar spindle biosynthesis", "bipolar spindle formation", "spindle biosynthesis", "spindle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051225" ; a owl:Class ; rdfs:label "spindle assembly" ; rdfs:subClassOf obo:GO_0007051, obo:GO_0140694, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007059 ] . obo:GO_0051231 obo:IAO_0000115 "The cell cycle process in which the distance is lengthened between poles of the spindle." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051231" ; a owl:Class ; rdfs:label "spindle elongation" ; rdfs:subClassOf obo:GO_0007017, obo:GO_0022402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007051 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098813 ] . obo:GO_0051232 obo:IAO_0000115 "The lengthening of the distance between poles of the spindle during a meiotic cell cycle." ; oboInOwl:hasExactSynonym "spindle elongation during meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051232" ; a owl:Class ; rdfs:label "meiotic spindle elongation" ; rdfs:subClassOf obo:GO_0051231, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000212 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045132 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051231 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051234 obo:IAO_0000115 "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24200"^^xsd:anyURI ; oboInOwl:hasExactSynonym "establishment of localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051234" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_agr, go:goslim_flybase_ribbon, go:goslim_mouse, go:goslim_pir ; a owl:Class ; rdfs:label "establishment of localization" ; rdfs:subClassOf obo:GO_0051179 . obo:GO_0051235 obo:IAO_0000115 "Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere." ; oboInOwl:hasExactSynonym "maintenance of localization" ; oboInOwl:hasNarrowSynonym "retention", "sequestering", "storage" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051235" ; a owl:Class ; rdfs:label "maintenance of location" ; rdfs:subClassOf obo:GO_0051179 . obo:GO_0051236 obo:IAO_0000115 "The directed movement of RNA to a specific location." ; oboInOwl:hasExactSynonym "RNA positioning", "RNA recruitment", "establishment of RNA localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051236" ; a owl:Class ; rdfs:label "establishment of RNA localization" ; rdfs:subClassOf obo:GO_0051234, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006403 ] . obo:GO_0051239 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051239" ; a owl:Class ; rdfs:label "regulation of multicellular organismal process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032501 ] ) ] . obo:GO_0051240 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ; oboInOwl:hasExactSynonym "up regulation of multicellular organismal process", "up-regulation of multicellular organismal process", "upregulation of multicellular organismal process" ; oboInOwl:hasNarrowSynonym "activation of multicellular organismal process", "stimulation of multicellular organismal process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051240" ; a owl:Class ; rdfs:label "positive regulation of multicellular organismal process" ; rdfs:subClassOf obo:GO_0048518, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032501 ] ) ] . obo:GO_0051241 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs." ; oboInOwl:hasExactSynonym "down regulation of multicellular organismal process", "down-regulation of multicellular organismal process", "downregulation of multicellular organismal process" ; oboInOwl:hasNarrowSynonym "inhibition of multicellular organismal process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051241" ; a owl:Class ; rdfs:label "negative regulation of multicellular organismal process" ; rdfs:subClassOf obo:GO_0048519, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032501 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032501 ] ) ] . obo:GO_0051246 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0032268" ; oboInOwl:hasExactSynonym "regulation of protein metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cellular protein metabolic process", "regulation of cellular protein metabolism" ; oboInOwl:id "GO:0051246" ; a owl:Class ; rdfs:label "regulation of protein metabolic process" ; rdfs:subClassOf obo:GO_0051171, obo:GO_0060255, obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019538 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0019538 ] ) ] . obo:GO_0051247 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0032270" ; oboInOwl:hasExactSynonym "positive regulation of cellular protein metabolic process", "positive regulation of cellular protein metabolism", "positive regulation of protein metabolism", "up regulation of cellular protein metabolic process", "up regulation of protein metabolic process", "up-regulation of cellular protein metabolic process", "up-regulation of protein metabolic process", "upregulation of cellular protein metabolic process", "upregulation of protein metabolic process" ; oboInOwl:hasNarrowSynonym "activation of cellular protein metabolic process", "activation of protein metabolic process", "stimulation of cellular protein metabolic process", "stimulation of protein metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051247" ; a owl:Class ; rdfs:label "positive regulation of protein metabolic process" ; rdfs:subClassOf obo:GO_0010604, obo:GO_0051173, obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019538 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0019538 ] ) ] . obo:GO_0051248 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0032269" ; oboInOwl:hasExactSynonym "down regulation of cellular protein metabolic process", "down regulation of protein metabolic process", "down-regulation of cellular protein metabolic process", "down-regulation of protein metabolic process", "downregulation of cellular protein metabolic process", "downregulation of protein metabolic process", "negative regulation of cellular protein metabolic process", "negative regulation of cellular protein metabolism", "negative regulation of protein metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of cellular protein metabolic process", "inhibition of protein metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051248" ; a owl:Class ; rdfs:label "negative regulation of protein metabolic process" ; rdfs:subClassOf obo:GO_0010605, obo:GO_0051172, obo:GO_0051246, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019538 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0019538 ] ) ] . obo:GO_0051252 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA." ; oboInOwl:hasExactSynonym "regulation of RNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051252" ; a owl:Class ; rdfs:label "regulation of RNA metabolic process" ; rdfs:subClassOf obo:GO_0019219, obo:GO_0060255, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016070 ] ) ] . obo:GO_0051253 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA." ; oboInOwl:hasExactSynonym "down regulation of RNA metabolic process", "down-regulation of RNA metabolic process", "downregulation of RNA metabolic process", "negative regulation of RNA metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of RNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051253" ; a owl:Class ; rdfs:label "negative regulation of RNA metabolic process" ; rdfs:subClassOf obo:GO_0010605, obo:GO_0045934, obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016070 ] ) ] . obo:GO_0051254 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA." ; oboInOwl:hasExactSynonym "positive regulation of RNA metabolism", "up regulation of RNA metabolic process", "up-regulation of RNA metabolic process", "upregulation of RNA metabolic process" ; oboInOwl:hasNarrowSynonym "activation of RNA metabolic process", "stimulation of RNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051254" ; a owl:Class ; rdfs:label "positive regulation of RNA metabolic process" ; rdfs:subClassOf obo:GO_0010604, obo:GO_0045935, obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016070 ] ) ] . obo:GO_0051258 obo:IAO_0000115 "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein." ; oboInOwl:hasExactSynonym "protein polymer biosynthesis", "protein polymer biosynthetic process", "protein polymer formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051258" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "protein polymerization" ; rdfs:subClassOf obo:GO_0065003 . obo:GO_0051259 obo:IAO_0000115 "The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-04-05T09:57:49Z" ; oboInOwl:hasAlternativeId "GO:0035786" ; oboInOwl:hasBroadSynonym "protein oligomer biosynthesis", "protein oligomer biosynthetic process" ; oboInOwl:hasExactSynonym "protein oligomer assembly", "protein oligomer formation", "protein oligomerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein multimerization" ; oboInOwl:id "GO:0051259" ; a owl:Class ; rdfs:label "protein complex oligomerization" ; rdfs:subClassOf obo:GO_0065003 . obo:GO_0051261 obo:IAO_0000115 "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein." ; oboInOwl:hasExactSynonym "protein polymer breakdown", "protein polymer catabolic process", "protein polymer catabolism", "protein polymer degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051261" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "protein depolymerization" ; rdfs:subClassOf obo:GO_0032984 . obo:GO_0051276 obo:IAO_0000115 "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22811"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/4585"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006323", "GO:0007001", "GO:0051277" ; oboInOwl:hasExactSynonym "DNA condensation", "chromosome organisation" ; oboInOwl:hasNarrowSynonym "DNA packaging" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosome organization and biogenesis", "maintenance of genome integrity", "nuclear genome maintenance" ; oboInOwl:id "GO:0051276" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:label "chromosome organization" ; rdfs:subClassOf obo:GO_0006996 . obo:GO_0051293 obo:IAO_0000115 "The directed movement of the spindle to a specific location in the cell." ; oboInOwl:hasExactSynonym "establishment of spindle localisation", "spindle positioning" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051293" ; a owl:Class ; rdfs:label "establishment of spindle localization" ; rdfs:subClassOf obo:GO_0000226, obo:GO_0051649, obo:GO_0051653, obo:GO_0051656 . obo:GO_0051294 obo:IAO_0000115 "Any process that set the alignment of spindle relative to other cellular structures." ; oboInOwl:hasExactSynonym "orienting of spindle", "spindle orientation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051294" ; a owl:Class ; rdfs:label "establishment of spindle orientation" ; rdfs:subClassOf obo:GO_0051293, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030010 ] . obo:GO_0051295 obo:IAO_0000115 "The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs." ; oboInOwl:hasExactSynonym "establishment of meiotic spindle localisation", "meiotic spindle positioning", "spindle positioning involved in meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "spindle positioning during meiosis" ; oboInOwl:id "GO:0051295" ; a owl:Class ; rdfs:label "establishment of meiotic spindle localization" ; rdfs:subClassOf obo:GO_0051293, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051293 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051296 obo:IAO_0000115 "Any process that set the alignment of meiotic spindle relative to other cellular structures." ; oboInOwl:hasExactSynonym "establishment of spindle orientation involved in meiotic cell cycle", "meiotic spindle orientation", "orienting of meiotic spindle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "establishment of spindle orientation during meiosis" ; oboInOwl:id "GO:0051296" ; a owl:Class ; rdfs:label "establishment of meiotic spindle orientation" ; rdfs:subClassOf obo:GO_0051294, obo:GO_0051295 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051294 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051301 obo:IAO_0000115 "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells." ; oboInOwl:hasDbXref "Wikipedia:Cell_division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051301" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_pir ; a owl:Class ; rdfs:comment "Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division." ; rdfs:label "cell division" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0051302 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051302" ; a owl:Class ; rdfs:label "regulation of cell division" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051301 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051301 ] ) ] . obo:GO_0051303 obo:IAO_0000115 "The directed movement of a chromosome to a specific location." ; oboInOwl:hasExactSynonym "chromosome positioning", "establishment of chromosome localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051303" ; a owl:Class ; rdfs:label "establishment of chromosome localization" ; rdfs:subClassOf obo:GO_0050000, obo:GO_0051649, obo:GO_0051656 . obo:GO_0051304 obo:IAO_0000115 "The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II)." ; oboInOwl:hasAlternativeId "GO:0034500" ; oboInOwl:hasNarrowSynonym "rDNA separation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromatid release" ; oboInOwl:id "GO:0051304" ; a owl:Class ; rdfs:label "chromosome separation" ; rdfs:subClassOf obo:GO_0022402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007059 ] . obo:GO_0051306 obo:IAO_0000115 "The process in which sister chromatids are physically detached from each other during mitosis." ; oboInOwl:hasExactSynonym "mitotic sister chromatid resolution", "sister chromatid separation during mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "chromosome separation during mitosis", "mitotic chromosome separation" ; oboInOwl:id "GO:0051306" ; a owl:Class ; rdfs:label "mitotic sister chromatid separation" ; rdfs:subClassOf obo:GO_0051304, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ] . obo:GO_0051307 obo:IAO_0000115 "The process in which chromosomes are physically detached from each other during meiosis." ; oboInOwl:hasExactSynonym "chromosome separation during meiosis", "meiotic chromosome resolution" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051307" ; a owl:Class ; rdfs:label "meiotic chromosome separation" ; rdfs:subClassOf obo:GO_0051304, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045132 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051304 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051308 obo:IAO_0000115 "The process in which paired chromosomes are physically detached from each other during male meiosis." ; oboInOwl:hasExactSynonym "chromosome separation during male meiosis", "male meiosis chromosome resolution" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051308" ; a owl:Class ; rdfs:label "male meiosis chromosome separation" ; rdfs:subClassOf obo:GO_0007060, obo:GO_0051307 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051304 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007140 ] ) ] . obo:GO_0051309 obo:IAO_0000115 "The process in which paired chromosomes are physically detached from each other during female meiosis." ; oboInOwl:hasExactSynonym "chromosome separation during female meiosis", "female meiosis chromosome resolution" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051309" ; a owl:Class ; rdfs:label "female meiosis chromosome separation" ; rdfs:subClassOf obo:GO_0016321, obo:GO_0051307 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051304 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007143 ] ) ] . obo:GO_0051310 obo:IAO_0000115 "A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25547"^^xsd:anyURI ; oboInOwl:hasNarrowSynonym "chromosome congression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051310" ; a owl:Class ; rdfs:label "metaphase chromosome alignment" ; rdfs:subClassOf obo:GO_0051303, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098813 ] . obo:GO_0051311 obo:IAO_0000115 "A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25547"^^xsd:anyURI ; oboInOwl:hasExactSynonym "metaphase plate congression during meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051311" ; a owl:Class ; rdfs:label "meiotic metaphase chromosome alignment" ; rdfs:subClassOf obo:GO_0051310, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045132 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051310 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051318 obo:IAO_0000115 "The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis." ; oboInOwl:hasDbXref "Wikipedia:G1_phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051318" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "G1 phase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051325 ] . obo:GO_0051320 obo:IAO_0000115 "The cell cycle phase, following G1, during which DNA synthesis takes place." ; oboInOwl:hasDbXref "Wikipedia:S_phase" ; oboInOwl:hasExactSynonym "S-phase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051320" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "S phase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051325 ] . obo:GO_0051321 obo:IAO_0000115 "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24599"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0007126" ; oboInOwl:hasDbXref "Wikipedia:Meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiosis" ; oboInOwl:id "GO:0051321" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_yeast ; a owl:Class ; rdfs:comment "Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle." ; rdfs:label "meiotic cell cycle" ; rdfs:subClassOf obo:GO_0007049, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0019953 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0140013 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007049 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0051325 obo:IAO_0000115 "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs." ; oboInOwl:hasBroadSynonym "resting phase" ; oboInOwl:hasDbXref "Wikipedia:Interphase" ; oboInOwl:hasExactSynonym "karyostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051325" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "interphase" ; rdfs:subClassOf obo:GO_0022403 . obo:GO_0051326 obo:IAO_0000115 "The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts." ; oboInOwl:hasDbXref "Wikipedia:Telophase" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051326" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "telophase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000279 ] . obo:GO_0051327 obo:IAO_0000115 "A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle." ; oboInOwl:hasExactSynonym "M phase of meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051327" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiotic M phase" ; rdfs:subClassOf obo:GO_0000279, obo:GO_0098762 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000279 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051328 obo:IAO_0000115 "The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA." ; oboInOwl:hasExactSynonym "interphase of meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051328" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiotic interphase" ; rdfs:subClassOf obo:GO_0051325, obo:GO_0098762 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051325 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051329 obo:IAO_0000115 "The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs." ; oboInOwl:hasExactSynonym "interphase of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051329" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "mitotic interphase" ; rdfs:subClassOf obo:GO_0051325, obo:GO_0098763 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051325 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0051333 obo:IAO_0000115 "The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20636"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiotic nuclear envelope reassembly" ; oboInOwl:id "GO:0051333" ; a owl:Class ; rdfs:label "meiotic nuclear membrane reassembly" ; rdfs:subClassOf obo:GO_0031468, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031468 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051334 obo:IAO_0000115 "The reformation of the nuclear membranes during meiosis I." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20636"^^xsd:anyURI ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiosis I nuclear envelope reassembly" ; oboInOwl:id "GO:0051334" ; a owl:Class ; rdfs:label "meiosis I nuclear membrane reassembly" ; rdfs:subClassOf obo:GO_0051333, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031468 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0051336 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3." ; oboInOwl:hasExactSynonym "hydrolase regulator" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051336" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "regulation of hydrolase activity" ; rdfs:subClassOf obo:GO_0050790, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016787 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016787 ] ) ] . obo:GO_0051338 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2." ; oboInOwl:hasExactSynonym "transferase regulator" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051338" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead." ; rdfs:label "regulation of transferase activity" ; rdfs:subClassOf obo:GO_0050790, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016740 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016740 ] ) ] . obo:GO_0051345 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds." ; oboInOwl:hasExactSynonym "hydrolase activator", "up regulation of hydrolase activity", "up-regulation of hydrolase activity", "upregulation of hydrolase activity" ; oboInOwl:hasNarrowSynonym "activation of hydrolase activity", "stimulation of hydrolase activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051345" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of hydrolase activity" ; rdfs:subClassOf obo:GO_0043085, obo:GO_0051336, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016787 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016787 ] ) ] . obo:GO_0051346 obo:IAO_0000115 "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds." ; oboInOwl:hasExactSynonym "down regulation of hydrolase activity", "down-regulation of hydrolase activity", "downregulation of hydrolase activity", "hydrolase inhibitor" ; oboInOwl:hasNarrowSynonym "inhibition of hydrolase activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051346" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of hydrolase activity" ; rdfs:subClassOf obo:GO_0043086, obo:GO_0051336, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016787 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016787 ] ) ] . obo:GO_0051347 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." ; oboInOwl:hasExactSynonym "transferase activator", "up regulation of transferase activity", "up-regulation of transferase activity", "upregulation of transferase activity" ; oboInOwl:hasNarrowSynonym "activation of transferase activity", "stimulation of transferase activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051347" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead." ; rdfs:label "positive regulation of transferase activity" ; rdfs:subClassOf obo:GO_0043085, obo:GO_0051338, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016740 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016740 ] ) ] . obo:GO_0051348 obo:IAO_0000115 "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor." ; oboInOwl:hasExactSynonym "down regulation of transferase activity", "down-regulation of transferase activity", "downregulation of transferase activity", "transferase inhibitor" ; oboInOwl:hasNarrowSynonym "inhibition of transferase activity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051348" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead." ; rdfs:label "negative regulation of transferase activity" ; rdfs:subClassOf obo:GO_0043086, obo:GO_0051338, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016740 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016740 ] ) ] . obo:GO_0051402 obo:IAO_0000115 "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system." ; oboInOwl:hasExactSynonym "apoptosis of neuronal cells", "apoptosis of neurons", "neuron programmed cell death by apoptosis", "neuronal cell apoptosis", "neuronal cell programmed cell death by apoptosis", "programmed cell death of neuronal cells by apoptosis", "programmed cell death of neurons by apoptosis", "programmed cell death, neuronal cells", "programmed cell death, neurons" ; oboInOwl:hasNarrowSynonym "neuron apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051402" ; a owl:Class ; rdfs:label "neuron apoptotic process" ; rdfs:subClassOf obo:GO_0006915 . obo:GO_0051445 obo:IAO_0000115 "Any process that modulates the rate or extent of progression through the meiotic cell cycle." ; oboInOwl:hasExactSynonym "meiotic cell cycle modulation", "meiotic cell cycle regulation", "modulation of meiotic cell cycle progression", "regulation of meiotic cell cycle progression", "regulation of progression through meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "meiotic cell cycle regulator" ; oboInOwl:id "GO:0051445" ; a owl:Class ; rdfs:label "regulation of meiotic cell cycle" ; rdfs:subClassOf obo:GO_0051726, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051446 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle." ; oboInOwl:hasExactSynonym "positive regulation of meiotic cell cycle progression", "positive regulation of progression through meiotic cell cycle", "up regulation of progression through meiotic cell cycle", "up-regulation of progression through meiotic cell cycle", "upregulation of progression through meiotic cell cycle" ; oboInOwl:hasNarrowSynonym "activation of progression through meiotic cell cycle", "stimulation of progression through meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051446" ; a owl:Class ; rdfs:label "positive regulation of meiotic cell cycle" ; rdfs:subClassOf obo:GO_0045787, obo:GO_0051445, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051447 obo:IAO_0000115 "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle." ; oboInOwl:hasExactSynonym "down regulation of progression through meiotic cell cycle", "down-regulation of progression through meiotic cell cycle", "downregulation of progression through meiotic cell cycle", "negative regulation of meiotic cell cycle progression", "negative regulation of progression through meiotic cell cycle" ; oboInOwl:hasNarrowSynonym "inhibition of progression through meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051447" ; a owl:Class ; rdfs:label "negative regulation of meiotic cell cycle" ; rdfs:subClassOf obo:GO_0045786, obo:GO_0051445, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0051452 obo:IAO_0000115 "Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion." ; oboInOwl:hasExactSynonym "cell pH reduction", "cellular acidification", "reduction of cellular pH", "reduction of pH in cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intracellular acidification" ; oboInOwl:id "GO:0051452" ; a owl:Class ; rdfs:label "intracellular pH reduction" ; rdfs:subClassOf obo:GO_0051453 . obo:GO_0051453 obo:IAO_0000115 "Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion." ; oboInOwl:hasExactSynonym "cell pH regulation", "cellular pH regulation", "pH regulation in cell", "regulation of cell pH" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051453" ; a owl:Class ; rdfs:label "regulation of intracellular pH" ; rdfs:subClassOf obo:GO_0030641, obo:GO_0065008 . obo:GO_0051457 obo:IAO_0000115 "Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus." ; oboInOwl:hasExactSynonym "maintenance of nuclear protein localization", "maintenance of protein location in cell nucleus" ; oboInOwl:hasNarrowSynonym "nuclear protein retention", "nuclear protein sequestering", "nuclear protein sequestration", "protein retention in nucleus", "protein sequestration in nucleus", "protein storage in nucleus", "protein-nuclear retention", "sequestration of protein in nucleus", "storage of protein in nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "maintenance of protein localization in nucleus" ; oboInOwl:id "GO:0051457" ; a owl:Class ; rdfs:label "maintenance of protein location in nucleus" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034504 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0051493 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ; oboInOwl:hasExactSynonym "regulation of cytoskeleton organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0051493" ; a owl:Class ; rdfs:label "regulation of cytoskeleton organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007010 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007010 ] ) ] . obo:GO_0051494 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ; oboInOwl:hasExactSynonym "down regulation of cytoskeleton organization", "down-regulation of cytoskeleton organization", "downregulation of cytoskeleton organization", "negative regulation of cytoskeleton organisation" ; oboInOwl:hasNarrowSynonym "inhibition of cytoskeleton organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0051494" ; a owl:Class ; rdfs:label "negative regulation of cytoskeleton organization" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0051493, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007010 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007010 ] ) ] . obo:GO_0051495 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures." ; oboInOwl:hasExactSynonym "positive regulation of cytoskeleton organisation", "up regulation of cytoskeleton organization", "up-regulation of cytoskeleton organization", "upregulation of cytoskeleton organization" ; oboInOwl:hasNarrowSynonym "activation of cytoskeleton organization", "stimulation of cytoskeleton organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cytoskeleton organization and biogenesis" ; oboInOwl:id "GO:0051495" ; a owl:Class ; rdfs:label "positive regulation of cytoskeleton organization" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0051493, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007010 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007010 ] ) ] . obo:GO_0051588 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051588" ; a owl:Class ; rdfs:label "regulation of neurotransmitter transport" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006836 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006836 ] ) ] . obo:GO_0051589 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "down regulation of neurotransmitter transport", "down-regulation of neurotransmitter transport", "downregulation of neurotransmitter transport" ; oboInOwl:hasNarrowSynonym "inhibition of neurotransmitter transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051589" ; a owl:Class ; rdfs:label "negative regulation of neurotransmitter transport" ; rdfs:subClassOf obo:GO_0051051, obo:GO_0051588, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006836 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006836 ] ) ] . obo:GO_0051590 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:hasExactSynonym "up regulation of neurotransmitter transport", "up-regulation of neurotransmitter transport", "upregulation of neurotransmitter transport" ; oboInOwl:hasNarrowSynonym "activation of neurotransmitter transport", "stimulation of neurotransmitter transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051590" ; a owl:Class ; rdfs:label "positive regulation of neurotransmitter transport" ; rdfs:subClassOf obo:GO_0051050, obo:GO_0051588, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006836 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006836 ] ) ] . obo:GO_0051640 obo:IAO_0000115 "Any process in which an organelle is transported to, and/or maintained in, a specific location." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI ; oboInOwl:hasExactSynonym "establishment and maintenance of organelle localization", "organelle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051640" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "organelle localization" ; rdfs:subClassOf obo:GO_0051179 . obo:GO_0051641 obo:IAO_0000115 "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-12-18T14:04:32Z" ; oboInOwl:hasAlternativeId "GO:1902580" ; oboInOwl:hasExactSynonym "cellular localisation", "establishment and maintenance of cellular localization", "establishment and maintenance of localization in cell or cell membrane", "single organism cellular localization" ; oboInOwl:hasNarrowSynonym "intracellular localization", "localization within cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism cellular localization" ; oboInOwl:id "GO:0051641" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "cellular localization" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0051179 . obo:GO_0051647 obo:IAO_0000115 "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell." ; oboInOwl:hasExactSynonym "cell nucleus localization", "establishment and maintenance of nucleus localization", "localization of nucleus", "nucleus localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051647" ; a owl:Class ; rdfs:label "nucleus localization" ; rdfs:subClassOf obo:GO_0051640 . obo:GO_0051648 obo:IAO_0000115 "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location." ; oboInOwl:hasExactSynonym "cytoplasmic vesicle localization", "establishment and maintenance of vesicle localization", "vesicle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051648" ; a owl:Class ; rdfs:label "vesicle localization" ; rdfs:subClassOf obo:GO_0051640 . obo:GO_0051649 obo:IAO_0000115 "Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation." ; oboInOwl:hasExactSynonym "establishment of localisation in cell" ; oboInOwl:hasNarrowSynonym "establishment of intracellular localization", "establishment of localization within cell", "positioning within cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "establishment of cellular localization" ; oboInOwl:id "GO:0051649" ; a owl:Class ; rdfs:label "establishment of localization in cell" ; rdfs:subClassOf obo:GO_0051234, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051641 ] . obo:GO_0051650 obo:IAO_0000115 "The directed movement of a vesicle to a specific location." ; oboInOwl:hasExactSynonym "establishment of vesicle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051650" ; a owl:Class ; rdfs:label "establishment of vesicle localization" ; rdfs:subClassOf obo:GO_0051648, obo:GO_0051649, obo:GO_0051656 . obo:GO_0051651 obo:IAO_0000115 "Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere." ; oboInOwl:hasNarrowSynonym "cellular retention", "cellular sequestering", "cellular storage", "intracellular retention", "intracellular sequestering", "intracellular storage", "maintenance of intracellular localization", "maintenance of localization within cell", "retention within cell", "sequestering within cell", "storage within cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "maintenance of cellular localization", "maintenance of localization in cell" ; oboInOwl:id "GO:0051651" ; a owl:Class ; rdfs:label "maintenance of location in cell" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0051235, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051641 ] . obo:GO_0051653 obo:IAO_0000115 "Any process in which is the spindle is transported to, and/or maintained in, a specific location." ; oboInOwl:hasExactSynonym "establishment and maintenance of spindle localization", "spindle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051653" ; a owl:Class ; rdfs:label "spindle localization" ; rdfs:subClassOf obo:GO_0022402, obo:GO_0051640 . obo:GO_0051656 obo:IAO_0000115 "The directed movement of an organelle to a specific location." ; oboInOwl:hasExactSynonym "establishment of organelle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051656" ; a owl:Class ; rdfs:label "establishment of organelle localization" ; rdfs:subClassOf obo:GO_0051234, obo:GO_0051640 . obo:GO_0051673 obo:IAO_0000115 "The disruption of the cell membrane of another organism, leading to damage or temporary subversion of the membrane." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24079"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0044662" ; oboInOwl:hasExactSynonym "disruption by organism of host cell membrane", "disruption of membrane integrity in another organism", "membrane disruption in other organism", "perturbation of plasma membrane integrity in another organism" ; oboInOwl:hasNarrowSynonym "cytolysis, by membrane disruption, in other organism", "disruption by virus of host cell membrane", "membrane disruption in another organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051673" ; a owl:Class ; rdfs:label "disruption of plasma membrane integrity in another organism" ; rdfs:subClassOf obo:GO_0140975 . obo:GO_0051703 obo:IAO_0000115 "Any process in which an organism has an effect on an organism of the same species." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20191"^^xsd:anyURI ; oboInOwl:hasExactSynonym "intraspecies interaction between organisms", "intraspecies interaction with other organisms" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051703" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:label "biological process involved in intraspecies interaction between organisms" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0051707 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism." ; oboInOwl:hasAlternativeId "GO:0009613", "GO:0042828" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051707" ; a owl:Class ; rdfs:label "response to other organism" ; rdfs:subClassOf obo:GO_0043207, obo:GO_0044419 . obo:GO_0051716 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051716" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to stimulus" ; rdfs:subClassOf obo:GO_0009987, obo:GO_0050896 . obo:GO_0051726 obo:IAO_0000115 "Any process that modulates the rate or extent of progression through the cell cycle." ; oboInOwl:hasAlternativeId "GO:0000074", "GO:0007050", "GO:0071156", "GO:0071157", "GO:0071158", "GO:0071850" ; oboInOwl:hasExactSynonym "cell cycle modulation", "cell cycle regulation", "control of cell cycle progression", "modulation of cell cycle progression", "regulation of cell cycle progression", "regulation of progression through cell cycle" ; oboInOwl:hasNarrowSynonym "arrest of mitotic cell cycle progression", "cell cycle arrest", "mitotic cell cycle arrest", "negative regulation of cell cycle arrest", "positive regulation of cell cycle arrest", "regulation of cell cycle arrest" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cell cycle regulator", "tumor suppressor" ; oboInOwl:id "GO:0051726" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "regulation of cell cycle" ; rdfs:subClassOf obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007049 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007049 ] ) ] . obo:GO_0051781 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell division." ; oboInOwl:hasExactSynonym "up regulation of cell division", "up-regulation of cell division", "upregulation of cell division" ; oboInOwl:hasNarrowSynonym "activation of cell division", "stimulation of cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051781" ; a owl:Class ; rdfs:label "positive regulation of cell division" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0051302, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051301 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051301 ] ) ] . obo:GO_0051782 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division." ; oboInOwl:hasExactSynonym "down regulation of cell division", "down-regulation of cell division", "downregulation of cell division" ; oboInOwl:hasNarrowSynonym "inhibition of cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051782" ; a owl:Class ; rdfs:label "negative regulation of cell division" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0051302, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051301 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051301 ] ) ] . obo:GO_0051783 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051783" ; a owl:Class ; rdfs:label "regulation of nuclear division" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000280 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000280 ] ) ] . obo:GO_0051784 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ; oboInOwl:hasExactSynonym "down regulation of nuclear division", "down-regulation of nuclear division", "downregulation of nuclear division" ; oboInOwl:hasNarrowSynonym "inhibition of nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051784" ; a owl:Class ; rdfs:label "negative regulation of nuclear division" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0051783, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000280 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000280 ] ) ] . obo:GO_0051785 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information." ; oboInOwl:hasExactSynonym "up regulation of nuclear division", "up-regulation of nuclear division", "upregulation of nuclear division" ; oboInOwl:hasNarrowSynonym "activation of nuclear division", "stimulation of nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051785" ; a owl:Class ; rdfs:label "positive regulation of nuclear division" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0051783, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000280 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000280 ] ) ] . obo:GO_0051932 obo:IAO_0000115 "The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse." ; oboInOwl:hasExactSynonym "GABAergic synaptic transmission", "synaptic transmission, GABA mediated", "synaptic transmission, gamma-aminobutyric acid mediated", "synaptic transmission, gamma-aminobutyric acid-ergic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051932" ; a owl:Class ; rdfs:label "synaptic transmission, GABAergic" ; rdfs:subClassOf obo:GO_0007268 . obo:GO_0051960 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051960" ; a owl:Class ; rdfs:label "regulation of nervous system development" ; rdfs:subClassOf obo:GO_2000026, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007399 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007399 ] ) ] . obo:GO_0051961 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ; oboInOwl:hasExactSynonym "down regulation of nervous system development", "down-regulation of nervous system development", "downregulation of nervous system development" ; oboInOwl:hasNarrowSynonym "inhibition of nervous system development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051961" ; a owl:Class ; rdfs:label "negative regulation of nervous system development" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0051241, obo:GO_0051960, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007399 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007399 ] ) ] . obo:GO_0051962 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue." ; oboInOwl:hasExactSynonym "up regulation of nervous system development", "up-regulation of nervous system development", "upregulation of nervous system development" ; oboInOwl:hasNarrowSynonym "activation of nervous system development", "stimulation of nervous system development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051962" ; a owl:Class ; rdfs:label "positive regulation of nervous system development" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0051240, obo:GO_0051960, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007399 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007399 ] ) ] . obo:GO_0051963 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ; oboInOwl:hasExactSynonym "regulation of synapse biogenesis", "regulation of synaptogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051963" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of synapse assembly" ; rdfs:subClassOf obo:GO_0050807, obo:GO_1901888, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007416 ] ) ] . obo:GO_0051964 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ; oboInOwl:hasExactSynonym "down regulation of synapse assembly", "down-regulation of synapse assembly", "downregulation of synapse assembly", "negative regulation of synapse biogenesis", "negative regulation of synaptogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of synapse assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051964" ; a owl:Class ; rdfs:label "negative regulation of synapse assembly" ; rdfs:subClassOf obo:GO_0051961, obo:GO_0051963, obo:GO_1901889, obo:GO_1905809, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007416 ] ) ] . obo:GO_0051965 obo:IAO_0000115 "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse." ; oboInOwl:hasExactSynonym "positive regulation of synapse biogenesis", "positive regulation of synaptogenesis", "up regulation of synapse assembly", "up-regulation of synapse assembly", "upregulation of synapse assembly" ; oboInOwl:hasNarrowSynonym "activation of synapse assembly", "stimulation of synapse assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051965" ; a owl:Class ; rdfs:label "positive regulation of synapse assembly" ; rdfs:subClassOf obo:GO_0051962, obo:GO_0051963, obo:GO_1901890, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007416 ] ) ] . obo:GO_0051983 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051983" ; a owl:Class ; rdfs:label "regulation of chromosome segregation" ; rdfs:subClassOf obo:GO_0010564, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007059 ] ) ] . obo:GO_0051984 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ; oboInOwl:hasExactSynonym "up regulation of chromosome segregation", "up-regulation of chromosome segregation", "upregulation of chromosome segregation" ; oboInOwl:hasNarrowSynonym "activation of chromosome segregation", "stimulation of chromosome segregation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051984" ; a owl:Class ; rdfs:label "positive regulation of chromosome segregation" ; rdfs:subClassOf obo:GO_0051983, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007059 ] ) ] . obo:GO_0051985 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets." ; oboInOwl:hasExactSynonym "down regulation of chromosome segregation", "down-regulation of chromosome segregation", "downregulation of chromosome segregation" ; oboInOwl:hasNarrowSynonym "inhibition of chromosome segregation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0051985" ; a owl:Class ; rdfs:label "negative regulation of chromosome segregation" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0051983, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007059 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007059 ] ) ] . obo:GO_0052689 obo:IAO_0000115 "Catalysis of the hydrolysis of a carboxylic ester bond." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24654"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0004091", "GO:0004302", "GO:0004759", "GO:0016789" ; oboInOwl:hasDbXref "EC:3.1.1.-", "KEGG_REACTION:R00630", "Reactome:R-HSA-5693691", "Reactome:R-HSA-8937442", "Reactome:R-HSA-9749792", "UM-BBD_reactionID:r1025" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "carboxylate esterase activity", "carboxylic esterase activity", "hydrolase activity acting on ester bonds" ; oboInOwl:id "GO:0052689" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "carboxylic ester hydrolase activity" ; rdfs:subClassOf obo:GO_0016788 . obo:GO_0055001 obo:IAO_0000115 "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate." ; oboInOwl:hasAlternativeId "GO:0048747" ; oboInOwl:hasExactSynonym "muscle fiber development", "muscle fibre development", "myofiber development", "myofibre development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055001" ; a owl:Class ; rdfs:label "muscle cell development" ; rdfs:subClassOf obo:GO_0048468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0042692 ] . obo:GO_0055037 obo:IAO_0000115 "An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane." ; oboInOwl:hasExactSynonym "endosomal recycling compartment" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "ERC", "endosome recycling compartment" ; oboInOwl:id "GO:0055037" ; a owl:Class ; rdfs:label "recycling endosome" ; rdfs:subClassOf obo:GO_0005768 . obo:GO_0055080 obo:IAO_0000115 "Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "cation homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055080" ; a owl:Class ; rdfs:label "monoatomic cation homeostasis" ; rdfs:subClassOf obo:GO_0050801 . obo:GO_0055082 obo:IAO_0000115 "A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24514"^^xsd:anyURI ; oboInOwl:hasExactSynonym "cellular chemical homeostasis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055082" ; a owl:Class ; rdfs:label "intracellular chemical homeostasis" ; rdfs:subClassOf obo:GO_0019725, obo:GO_0048878 . obo:GO_0055115 obo:IAO_0000115 "The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." ; oboInOwl:hasDbXref "Wikipedia:Diapause" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055115" ; a owl:Class ; rdfs:label "entry into diapause" ; rdfs:subClassOf obo:GO_0022611 . obo:GO_0055123 obo:IAO_0000115 "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0055123" ; a owl:Class ; rdfs:label "digestive system development" ; rdfs:subClassOf obo:GO_0048731 . obo:GO_0060090 obo:IAO_0000115 "The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way." ; oboInOwl:hasAlternativeId "GO:0032947" ; oboInOwl:hasExactSynonym "binding, bridging" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:hasRelatedSynonym "protein complex scaffold activity", "protein-containing complex scaffold activity" ; oboInOwl:id "GO:0060090" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:prokaryote_subset ; a owl:Class ; rdfs:label "molecular adaptor activity" ; rdfs:subClassOf obo:GO_0003674, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0005488 ] . obo:GO_0060097 obo:IAO_0000115 "The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060097" ; a owl:Class ; rdfs:label "cytoskeletal rearrangement involved in phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0007010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007010 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006911 ] ) ] . obo:GO_0060099 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060099" ; a owl:Class ; rdfs:label "regulation of phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0050764, obo:GO_1905153, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006911 ] ) ] . obo:GO_0060100 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060100" ; a owl:Class ; rdfs:label "positive regulation of phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0050766, obo:GO_0060099, obo:GO_1905155, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006911 ] ) ] . obo:GO_0060101 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060101" ; a owl:Class ; rdfs:label "negative regulation of phagocytosis, engulfment" ; rdfs:subClassOf obo:GO_0050765, obo:GO_0060099, obo:GO_1905154, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006911 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006911 ] ) ] . obo:GO_0060102 obo:IAO_0000115 "A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "collagen and cuticulin-based exoskeleton extracellular matrix" ; oboInOwl:id "GO:0060102" ; a owl:Class ; rdfs:label "collagen and cuticulin-based cuticle extracellular matrix" ; rdfs:subClassOf obo:GO_0062023 . obo:GO_0060106 obo:IAO_0000115 "The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0060106" ; a owl:Class ; rdfs:label "cortical layer of collagen and cuticulin-based cuticle extracellular matrix" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060102 ] . obo:GO_0060107 obo:IAO_0000115 "The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "annulae", "annular rings", "annule(s)", "annulus" ; oboInOwl:id "GO:0060107" ; a owl:Class ; rdfs:label "annuli extracellular matrix" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060106 ] . obo:GO_0060109 obo:IAO_0000115 "The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "medial layer struts" ; oboInOwl:id "GO:0060109" ; a owl:Class ; rdfs:label "medial layer of collagen and cuticulin-based cuticle extracellular matrix" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0060102 ] . obo:GO_0060142 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060142" ; a owl:Class ; rdfs:label "regulation of syncytium formation by plasma membrane fusion" ; rdfs:subClassOf obo:GO_0050793, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000768 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000768 ] ) ] . obo:GO_0060143 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060143" ; a owl:Class ; rdfs:label "positive regulation of syncytium formation by plasma membrane fusion" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0051130, obo:GO_0060142, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000768 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000768 ] ) ] . obo:GO_0060179 obo:IAO_0000115 "The specific behavior of a male organism that is associated with reproduction." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060179" ; a owl:Class ; rdfs:label "male mating behavior" ; rdfs:subClassOf obo:GO_0007617 . obo:GO_0060236 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle." ; oboInOwl:hasExactSynonym "regulation of mitotic spindle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of mitotic spindle organization and biogenesis" ; oboInOwl:id "GO:0060236" ; a owl:Class ; rdfs:label "regulation of mitotic spindle organization" ; rdfs:subClassOf obo:GO_0090224, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007052 ] ) ] . obo:GO_0060255 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060255" ; a owl:Class ; rdfs:label "regulation of macromolecule metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043170 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043170 ] ) ] . obo:GO_0060259 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food." ; oboInOwl:hasExactSynonym "regulation of feeding behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060259" ; a owl:Class ; rdfs:label "regulation of feeding behavior" ; rdfs:subClassOf obo:GO_0050795, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007631 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007631 ] ) ] . obo:GO_0060278 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060278" ; a owl:Class ; rdfs:label "regulation of ovulation" ; rdfs:subClassOf obo:GO_0051239, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030728 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030728 ] ) ] . obo:GO_0060279 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060279" ; a owl:Class ; rdfs:label "positive regulation of ovulation" ; rdfs:subClassOf obo:GO_0051240, obo:GO_0060278, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030728 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030728 ] ) ] . obo:GO_0060280 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060280" ; a owl:Class ; rdfs:label "negative regulation of ovulation" ; rdfs:subClassOf obo:GO_0051241, obo:GO_0060278, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030728 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030728 ] ) ] . obo:GO_0060281 obo:IAO_0000115 "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060281" ; a owl:Class ; rdfs:label "regulation of oocyte development" ; rdfs:subClassOf obo:GO_1905879, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048599 ] ) ] . obo:GO_0060282 obo:IAO_0000115 "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060282" ; a owl:Class ; rdfs:label "positive regulation of oocyte development" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0060281, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048599 ] ) ] . obo:GO_0060283 obo:IAO_0000115 "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060283" ; a owl:Class ; rdfs:label "negative regulation of oocyte development" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0060281, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048599 ] ) ] . obo:GO_0060284 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060284" ; a owl:Class ; rdfs:label "regulation of cell development" ; rdfs:subClassOf obo:GO_0045595, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048468 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048468 ] ) ] . obo:GO_0060293 obo:IAO_0000115 "Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line." ; oboInOwl:hasDbXref "Wikipedia:Germ_plasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0060293" ; a owl:Class ; rdfs:label "germ plasm" ; rdfs:subClassOf obo:GO_0045495 . obo:GO_0060322 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060322" ; a owl:Class ; rdfs:label "head development" ; rdfs:subClassOf obo:GO_0048856 . obo:GO_0060341 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell." ; oboInOwl:hasExactSynonym "regulation of cellular localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060341" ; a owl:Class ; rdfs:label "regulation of cellular localization" ; rdfs:subClassOf obo:GO_0032879, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051641 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051641 ] ) ] . obo:GO_0060404 obo:IAO_0000115 "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060404" ; a owl:Class ; rdfs:label "axonemal microtubule depolymerization" ; rdfs:subClassOf obo:GO_0010938, obo:GO_0061523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005930 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007019 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005930 ] ) ] . obo:GO_0060408 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060408" ; a owl:Class ; rdfs:label "regulation of acetylcholine metabolic process" ; rdfs:subClassOf obo:GO_0033238, obo:GO_0080090, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008291 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008291 ] ) ] . obo:GO_0060409 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060409" ; a owl:Class ; rdfs:label "positive regulation of acetylcholine metabolic process" ; rdfs:subClassOf obo:GO_0033240, obo:GO_0060408, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008291 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008291 ] ) ] . obo:GO_0060410 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060410" ; a owl:Class ; rdfs:label "negative regulation of acetylcholine metabolic process" ; rdfs:subClassOf obo:GO_0033239, obo:GO_0060408, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008291 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008291 ] ) ] . obo:GO_0060429 obo:IAO_0000115 "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060429" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "epithelium development" ; rdfs:subClassOf obo:GO_0009888 . obo:GO_0060456 obo:IAO_0000115 "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060456" ; a owl:Class ; rdfs:label "positive regulation of digestive system process" ; rdfs:subClassOf obo:GO_0044058, obo:GO_0051240, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022600 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022600 ] ) ] . obo:GO_0060457 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060457" ; a owl:Class ; rdfs:label "negative regulation of digestive system process" ; rdfs:subClassOf obo:GO_0044058, obo:GO_0051241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022600 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022600 ] ) ] . obo:GO_0060465 obo:IAO_0000115 "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "pharyngeal development" ; oboInOwl:id "GO:0060465" ; a owl:Class ; rdfs:label "pharynx development" ; rdfs:subClassOf obo:GO_0048856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048565 ] . obo:GO_0060467 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060467" ; a owl:Class ; rdfs:label "negative regulation of fertilization" ; rdfs:subClassOf obo:GO_0080154, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009566 ] ) ] . obo:GO_0060538 obo:IAO_0000115 "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-10T08:25:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060538" ; a owl:Class ; rdfs:label "skeletal muscle organ development" ; rdfs:subClassOf obo:GO_0007517 . obo:GO_0060560 obo:IAO_0000115 "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-28T08:42:53Z" ; oboInOwl:hasExactSynonym "differential growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060560" ; a owl:Class ; rdfs:label "developmental growth involved in morphogenesis" ; rdfs:subClassOf obo:GO_0048589, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0048589 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ) ] . obo:GO_0060561 obo:IAO_0000115 "Any apoptotic process that contributes to the shaping of an anatomical structure." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-04-28T09:17:27Z" ; oboInOwl:hasNarrowSynonym "apoptosis involved in morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "apoptosis involved in development", "morphogenetic apoptosis" ; oboInOwl:id "GO:0060561" ; a owl:Class ; rdfs:label "apoptotic process involved in morphogenesis" ; rdfs:subClassOf obo:GO_1902742, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0009653 ] ) ] . obo:GO_0060623 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T02:12:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060623" ; a owl:Class ; rdfs:label "regulation of chromosome condensation" ; rdfs:subClassOf obo:GO_0033044, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030261 ] ) ] . obo:GO_0060627 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T02:29:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060627" ; a owl:Class ; rdfs:label "regulation of vesicle-mediated transport" ; rdfs:subClassOf obo:GO_0050794, obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016192 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016192 ] ) ] . obo:GO_0060629 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T02:41:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060629" ; a owl:Class ; rdfs:label "regulation of homologous chromosome segregation" ; rdfs:subClassOf obo:GO_0051983, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045143 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045143 ] ) ] . obo:GO_0060631 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T02:55:19Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060631" ; a owl:Class ; rdfs:label "regulation of meiosis I" ; rdfs:subClassOf obo:GO_0040020, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0060632 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-05-18T03:07:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060632" ; a owl:Class ; rdfs:label "regulation of microtubule-based movement" ; rdfs:subClassOf obo:GO_0032886, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007018 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007018 ] ) ] . obo:GO_0060756 obo:IAO_0000115 "Behavior by which an organism locates food." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-06-22T02:46:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060756" ; a owl:Class ; rdfs:label "foraging behavior" ; rdfs:subClassOf obo:GO_0007610 . obo:GO_0060795 obo:IAO_0000115 "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-04T03:11:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060795" ; a owl:Class ; rdfs:label "cell fate commitment involved in formation of primary germ layer" ; rdfs:subClassOf obo:GO_0045165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001704 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045165 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001704 ] ) ] . obo:GO_0060903 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2009-08-14T01:06:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0060903" ; a owl:Class ; rdfs:label "positive regulation of meiosis I" ; rdfs:subClassOf obo:GO_0045836, obo:GO_0060631, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0061013 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-29T01:48:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of mRNA decay" ; oboInOwl:id "GO:0061013" ; a owl:Class ; rdfs:label "regulation of mRNA catabolic process" ; rdfs:subClassOf obo:GO_0010468, obo:GO_0031329, obo:GO_1903311, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006402 ] ) ] . obo:GO_0061014 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-01-29T01:58:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of mRNA decay" ; oboInOwl:id "GO:0061014" ; a owl:Class ; rdfs:label "positive regulation of mRNA catabolic process" ; rdfs:subClassOf obo:GO_0031331, obo:GO_0061013, obo:GO_1903313, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006402 ] ) ] . obo:GO_0061024 obo:IAO_0000115 "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-02-08T02:43:11Z" ; oboInOwl:hasAlternativeId "GO:0016044", "GO:0044802" ; oboInOwl:hasExactSynonym "cellular membrane organisation", "cellular membrane organization", "membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "membrane organization and biogenesis", "single-organism membrane organization" ; oboInOwl:id "GO:0061024" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "membrane organization" ; rdfs:subClassOf obo:GO_0016043 . obo:GO_0061025 obo:IAO_0000115 "The membrane organization process that joins two lipid bilayers to form a single membrane." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-02-08T02:48:06Z" ; oboInOwl:hasAlternativeId "GO:0006944", "GO:0044801" ; oboInOwl:hasDbXref "Wikipedia:Lipid_bilayer_fusion" ; oboInOwl:hasExactSynonym "cellular membrane fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single-organism membrane fusion" ; oboInOwl:id "GO:0061025" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "membrane fusion" ; rdfs:subClassOf obo:GO_0061024 . obo:GO_0061061 obo:IAO_0000115 "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-09T08:55:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061061" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "muscle structure development" ; rdfs:subClassOf obo:GO_0048856 . obo:GO_0061062 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T12:59:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061062" ; a owl:Class ; rdfs:label "regulation of nematode larval development" ; rdfs:subClassOf obo:GO_0048580, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002119 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0002119 ] ) ] . obo:GO_0061063 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:03:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061063" ; a owl:Class ; rdfs:label "positive regulation of nematode larval development" ; rdfs:subClassOf obo:GO_0048582, obo:GO_0061062, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002119 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0002119 ] ) ] . obo:GO_0061064 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:04:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061064" ; a owl:Class ; rdfs:label "negative regulation of nematode larval development" ; rdfs:subClassOf obo:GO_0048581, obo:GO_0061062, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002119 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0002119 ] ) ] . obo:GO_0061065 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:07:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061065" ; a owl:Class ; rdfs:label "regulation of dauer larval development" ; rdfs:subClassOf obo:GO_0061062, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040024 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0040024 ] ) ] . obo:GO_0061066 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:09:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061066" ; a owl:Class ; rdfs:label "positive regulation of dauer larval development" ; rdfs:subClassOf obo:GO_0061063, obo:GO_0061065, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040024 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0040024 ] ) ] . obo:GO_0061067 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-03-11T01:10:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061067" ; a owl:Class ; rdfs:label "negative regulation of dauer larval development" ; rdfs:subClassOf obo:GO_0061064, obo:GO_0061065, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040024 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0040024 ] ) ] . obo:GO_0061387 obo:IAO_0000115 "Any process that modulates the extent of cell growth." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-07-14T10:15:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061387" ; a owl:Class ; rdfs:label "regulation of extent of cell growth" ; rdfs:subClassOf obo:GO_0001558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0008361 ] . obo:GO_0061458 obo:IAO_0000115 "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-08-22T17:47:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061458" ; a owl:Class ; rdfs:label "reproductive system development" ; rdfs:subClassOf obo:GO_0048731 . obo:GO_0061523 obo:IAO_0000115 "A cellular process that results in the breakdown of a cilium." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-04-18T14:59:59Z" ; oboInOwl:hasExactSynonym "cilium resorption" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061523" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent." ; rdfs:label "cilium disassembly" ; rdfs:subClassOf obo:GO_0044782, obo:GO_1903008 . obo:GO_0061564 obo:IAO_0000115 "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation)." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-07-18T14:43:01Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061564" ; a owl:Class ; rdfs:label "axon development" ; rdfs:subClassOf obo:GO_0031175 . obo:GO_0061640 obo:IAO_0000115 "A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2014-08-22T14:21:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061640" ; a owl:Class ; rdfs:label "cytoskeleton-dependent cytokinesis" ; rdfs:subClassOf obo:GO_0000910 . obo:GO_0061642 obo:IAO_0000115 "The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2014-08-29T08:21:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061642" ; a owl:Class ; rdfs:label "chemoattraction of axon" ; rdfs:subClassOf obo:GO_0050918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050918 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ] ) ] . obo:GO_0061643 obo:IAO_0000115 "The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2014-08-29T08:35:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061643" ; a owl:Class ; rdfs:label "chemorepulsion of axon" ; rdfs:subClassOf obo:GO_0050919, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050919 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007411 ] ) ] . obo:GO_0061673 obo:IAO_0000115 "Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2014-12-08T18:27:20Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0061673" ; a owl:Class ; rdfs:label "mitotic spindle astral microtubule" ; rdfs:subClassOf obo:GO_0000235, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072686 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000235 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072686 ] ) ] . obo:GO_0061919 obo:IAO_0000115 "A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2017-07-13T19:42:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061919" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "process utilizing autophagic mechanism" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0061982 obo:IAO_0000115 "A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-02-14T22:27:20Z" ; oboInOwl:hasExactSynonym "first meiotic cell division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0061982" ; a owl:Class ; rdfs:label "meiosis I cell cycle process" ; rdfs:subClassOf obo:GO_1903046 . obo:GO_0062012 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of a small molecule metabolic process." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-03-19T14:11:54Z" ; oboInOwl:hasExactSynonym "regulation of small molecule metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062012" ; a owl:Class ; rdfs:label "regulation of small molecule metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044281 ] ) ] . obo:GO_0062013 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-03-19T14:25:10Z" ; oboInOwl:hasExactSynonym "positive regulation of small molecule metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062013" ; a owl:Class ; rdfs:label "positive regulation of small molecule metabolic process" ; rdfs:subClassOf obo:GO_0009893, obo:GO_0062012, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044281 ] ) ] . obo:GO_0062014 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-03-19T14:27:23Z" ; oboInOwl:hasExactSynonym "negative regulation of small molecule metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062014" ; a owl:Class ; rdfs:label "negative regulation of small molecule metabolic process" ; rdfs:subClassOf obo:GO_0009892, obo:GO_0062012, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044281 ] ) ] . obo:GO_0062023 obo:IAO_0000115 "An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-04-13T12:47:21Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0062023" ; a owl:Class ; rdfs:label "collagen-containing extracellular matrix" ; rdfs:subClassOf obo:GO_0031012 . obo:GO_0062033 obo:IAO_0000115 "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2018-04-23T14:32:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062033" ; a owl:Class ; rdfs:label "positive regulation of mitotic sister chromatid segregation" ; rdfs:subClassOf obo:GO_0033047, obo:GO_0051984, obo:GO_2001252, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000070 ] ) ] . obo:GO_0062125 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA)." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2019-05-30T16:45:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062125" ; a owl:Class ; rdfs:label "regulation of mitochondrial gene expression" ; rdfs:subClassOf obo:GO_0010468, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140053 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0140053 ] ) ] . obo:GO_0062197 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2019-12-10T14:42:03Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0062197" ; a owl:Class ; rdfs:label "cellular response to chemical stress" ; rdfs:subClassOf obo:GO_0033554, obo:GO_0070887 . obo:GO_0065003 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22580"^^xsd:anyURI ; oboInOwl:hasAlternativeId "GO:0006461", "GO:0034622", "GO:0043623" ; oboInOwl:hasExactSynonym "cellular protein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular macromolecule complex assembly", "cellular protein-containing complex assembly", "chaperone activity", "macromolecular complex assembly", "macromolecule complex assembly", "protein complex assembly", "protein complex formation" ; oboInOwl:id "GO:0065003" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_drosophila, go:goslim_generic, go:goslim_metagenomics, go:goslim_pir, go:goslim_pombe, go:prokaryote_subset ; a owl:Class ; rdfs:label "protein-containing complex assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0043933 . obo:GO_0065004 obo:IAO_0000115 "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex." ; oboInOwl:hasExactSynonym "DNA-protein complex assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0065004" ; a owl:Class ; rdfs:label "protein-DNA complex assembly" ; rdfs:subClassOf obo:GO_0065003, obo:GO_0071824 . obo:GO_0065007 obo:IAO_0000115 "Any process that modulates a measurable attribute of any biological process, quality or function." ; oboInOwl:hasBroadSynonym "regulation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0065007" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:label "biological regulation" ; rdfs:subClassOf obo:GO_0008150 . obo:GO_0065008 obo:IAO_0000115 "Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc." ; oboInOwl:hasExactSynonym "regulation of biological attribute", "regulation of biological characteristic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0065008" ; oboInOwl:inSubset go:goslim_pir ; a owl:Class ; rdfs:label "regulation of biological quality" ; rdfs:subClassOf obo:GO_0065007 . obo:GO_0065009 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding." ; oboInOwl:hasExactSynonym "regulation of a molecular function" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0065009" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir, go:goslim_plant ; a owl:Class ; rdfs:label "regulation of molecular function" ; rdfs:subClassOf obo:BFO_0000015, obo:GO_0065007, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003674 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003674 ] ) ] . obo:GO_0070013 obo:IAO_0000115 "An organelle lumen that is part of an intracellular organelle." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0070013" ; a owl:Class ; rdfs:label "intracellular organelle lumen" ; rdfs:subClassOf obo:GO_0043233, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043229 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031974 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043229 ] ) ] . obo:GO_0070125 obo:IAO_0000115 "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion." ; oboInOwl:hasExactSynonym "mitochondrial translation elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070125" ; a owl:Class ; rdfs:label "mitochondrial translational elongation" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0006414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0032543 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006414 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0070129 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ; oboInOwl:hasExactSynonym "regulation of mitochondrial protein anabolism", "regulation of mitochondrial protein biosynthesis", "regulation of mitochondrial protein formation", "regulation of mitochondrial protein synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070129" ; a owl:Class ; rdfs:label "regulation of mitochondrial translation" ; rdfs:subClassOf obo:GO_0006417, obo:GO_0062125, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032543 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032543 ] ) ] . obo:GO_0070130 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ; oboInOwl:hasExactSynonym "negative regulation of mitochondrial protein anabolism", "negative regulation of mitochondrial protein biosynthesis", "negative regulation of mitochondrial protein formation", "negative regulation of mitochondrial protein synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070130" ; a owl:Class ; rdfs:label "negative regulation of mitochondrial translation" ; rdfs:subClassOf obo:GO_0017148, obo:GO_0070129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032543 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032543 ] ) ] . obo:GO_0070131 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion." ; oboInOwl:hasExactSynonym "positive regulation of mitochondrial protein anabolism", "positive regulation of mitochondrial protein biosynthesis", "positive regulation of mitochondrial protein formation", "positive regulation of mitochondrial protein synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070131" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial translation" ; rdfs:subClassOf obo:GO_0045727, obo:GO_0070129, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032543 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032543 ] ) ] . obo:GO_0070160 obo:IAO_0000115 "A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other." ; oboInOwl:hasDbXref "Wikipedia:Tight_junction" ; oboInOwl:hasExactSynonym "occluding cell junction", "occluding junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0070160" ; a owl:Class ; rdfs:label "tight junction" ; rdfs:subClassOf obo:GO_0005911 . obo:GO_0070161 obo:IAO_0000115 "A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix." ; oboInOwl:hasExactSynonym "anchoring cell junction" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0070161" ; a owl:Class ; rdfs:label "anchoring junction" ; rdfs:subClassOf obo:GO_0030054 . obo:GO_0070192 obo:IAO_0000115 "A process of chromosome organization that is involved in a meiotic cell cycle." ; oboInOwl:hasExactSynonym "chromosome organisation involved in meiosis", "meiotic chromosome organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070192" ; a owl:Class ; rdfs:label "chromosome organization involved in meiotic cell cycle" ; rdfs:subClassOf obo:GO_0051276, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051276 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0070201 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location." ; oboInOwl:hasExactSynonym "regulation of establishment of protein localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070201" ; a owl:Class ; rdfs:label "regulation of establishment of protein localization" ; rdfs:subClassOf obo:GO_0032880, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045184 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045184 ] ) ] . obo:GO_0070265 obo:IAO_0000115 "OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24680"^^xsd:anyURI ; oboInOwl:hasBroadSynonym "necrosis" ; oboInOwl:hasExactSynonym "cellular necrosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070265" ; a owl:Class ; rdfs:comment """The reason for obsoletion is that this term represent an assay and not a GO process. The reason for obsoletion is that this represents a phenotype.""" ; rdfs:label "obsolete necrotic cell death" ; owl:deprecated true . obo:GO_0070382 obo:IAO_0000115 "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis." ; oboInOwl:hasExactSynonym "exocytic constitutive secretory pathway transport vesicle", "exocytotic vesicle" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0070382" ; a owl:Class ; rdfs:label "exocytic vesicle" ; rdfs:subClassOf obo:GO_0030133, obo:GO_0099503 . obo:GO_0070482 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070482" ; a owl:Class ; rdfs:label "response to oxygen levels" ; rdfs:subClassOf obo:GO_0009628 . obo:GO_0070507 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins." ; oboInOwl:hasExactSynonym "regulation of microtubule cytoskeleton organisation", "regulation of microtubule dynamics" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070507" ; a owl:Class ; rdfs:label "regulation of microtubule cytoskeleton organization" ; rdfs:subClassOf obo:GO_0032886, obo:GO_0051493, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000226 ] ) ] . obo:GO_0070585 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within the mitochondrion." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-04-24T02:31:18Z" ; oboInOwl:hasExactSynonym "protein localisation in mitochondrion", "protein localization in mitochondrion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070585" ; a owl:Class ; rdfs:label "protein localization to mitochondrion" ; rdfs:subClassOf obo:GO_0033365 . obo:GO_0070727 obo:IAO_0000115 "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-06-16T04:08:29Z" ; oboInOwl:hasExactSynonym "cellular macromolecule localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070727" ; a owl:Class ; rdfs:label "cellular macromolecule localization" ; rdfs:subClassOf obo:GO_0033036, obo:GO_0051641 . obo:GO_0070887 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-08-27T04:41:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070887" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to chemical stimulus" ; rdfs:subClassOf obo:GO_0042221, obo:GO_0051716 . obo:GO_0070925 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-09-15T03:00:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070925" ; oboInOwl:inSubset go:goslim_yeast ; a owl:Class ; rdfs:label "organelle assembly" ; rdfs:subClassOf obo:GO_0006996, obo:GO_0022607 . obo:GO_0070972 obo:IAO_0000115 "A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-10-02T12:43:34Z" ; oboInOwl:hasExactSynonym "protein localisation in endoplasmic reticulum", "protein localization in ER", "protein localization in endoplasmic reticulum" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0070972" ; a owl:Class ; rdfs:label "protein localization to endoplasmic reticulum" ; rdfs:subClassOf obo:GO_0033365 . obo:GO_0071025 obo:IAO_0000115 "A process that identifies and degrades defective or aberrant RNAs." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2009-07-28T03:10:28Z" ; oboInOwl:hasExactSynonym "RNA quality control", "aberrant RNA catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071025" ; a owl:Class ; rdfs:label "RNA surveillance" ; rdfs:subClassOf obo:GO_0006401 . obo:GO_0071026 obo:IAO_0000115 "The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2009-07-28T03:14:03Z" ; oboInOwl:hasExactSynonym "cytoplasmic RNA quality control", "cytoplasmic aberrant RNA catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071026" ; a owl:Class ; rdfs:label "cytoplasmic RNA surveillance" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0071025, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0071027 obo:IAO_0000115 "A process that identifies and degrades defective or aberrant RNAs within the nucleus." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2009-07-28T03:45:02Z" ; oboInOwl:hasExactSynonym "nuclear RNA quality control", "nuclear aberrant RNA catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071027" ; a owl:Class ; rdfs:label "nuclear RNA surveillance" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0071025, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0071028 obo:IAO_0000115 "A process that identifies and degrades defective or aberrant mRNAs within the nucleus." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22342"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2009-07-28T04:14:29Z" ; oboInOwl:hasAlternativeId "GO:0071033", "GO:0071048", "GO:0071049" ; oboInOwl:hasExactSynonym "nuclear aberrant mRNA catabolic process", "nuclear mRNA quality control" ; oboInOwl:hasNarrowSynonym "nuclear retention of pre-mRNA at the site of transcription", "nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription", "nuclear retention of unspliced pre-mRNA at the site of transcription" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071028" ; a owl:Class ; rdfs:label "nuclear mRNA surveillance" ; rdfs:subClassOf obo:GO_0000956, obo:GO_0071027 . obo:GO_0071166 obo:IAO_0000115 "Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-11-19T04:46:05Z" ; oboInOwl:hasExactSynonym "RNP localization", "cellular ribonucleoprotein complex localization", "establishment and maintenance of ribonucleoprotein complex localization", "ribonucleoprotein complex localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071166" ; a owl:Class ; rdfs:label "ribonucleoprotein complex localization" ; rdfs:subClassOf obo:GO_0051641 . obo:GO_0071173 obo:IAO_0000115 "A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-11-23T12:36:57Z" ; oboInOwl:hasAlternativeId "GO:0072486" ; oboInOwl:hasBroadSynonym "SAC" ; oboInOwl:hasExactSynonym "signal transduction involved in spindle assembly checkpoint", "spindle assembly checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071173" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle assembly checkpoint (mitotic or meiotic)." ; rdfs:label "spindle assembly checkpoint signaling" ; rdfs:subClassOf obo:GO_0031577 . obo:GO_0071174 obo:IAO_0000115 "A signaling process that contributes to a mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20935"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-11-23T12:41:36Z" ; oboInOwl:hasAlternativeId "GO:0072477" ; oboInOwl:hasExactSynonym "mitotic cell cycle spindle checkpoint", "mitotic spindle checkpoint", "signal transduction involved in mitotic cell cycle spindle checkpoint", "signal transduction involved in mitotic spindle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "topo II checkpoint", "topoisomerase II checkpoint" ; oboInOwl:id "GO:0071174" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation checkpoints)." ; rdfs:label "mitotic spindle checkpoint signaling" ; rdfs:subClassOf obo:GO_0007093, obo:GO_0031577 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031577 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0071214 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-03T01:02:11Z" ; oboInOwl:hasNarrowSynonym "cellular response to abiotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071214" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to abiotic stimulus" ; rdfs:subClassOf obo:GO_0009628, obo:GO_0104004 . obo:GO_0071216 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-03T01:09:08Z" ; oboInOwl:hasNarrowSynonym "cellular response to biotic stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071216" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "cellular response to biotic stimulus" ; rdfs:subClassOf obo:GO_0009607, obo:GO_0051716 . obo:GO_0071310 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-10T04:46:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071310" ; a owl:Class ; rdfs:label "cellular response to organic substance" ; rdfs:subClassOf obo:GO_0010033, obo:GO_0070887 . obo:GO_0071470 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T11:45:33Z" ; oboInOwl:hasExactSynonym "cellular osmotic response", "cellular osmotic stress response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071470" ; a owl:Class ; rdfs:label "cellular response to osmotic stress" ; rdfs:subClassOf obo:GO_0006970, obo:GO_0062197, obo:GO_0071214 . obo:GO_0071478 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T01:59:37Z" ; oboInOwl:hasExactSynonym "cellular response to electromagnetic radiation stimulus", "cellular response to radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071478" ; a owl:Class ; rdfs:comment "Note that 'radiation' refers to electromagnetic radiation of any wavelength." ; rdfs:label "cellular response to radiation" ; rdfs:subClassOf obo:GO_0009314, obo:GO_0071214 . obo:GO_0071479 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T02:00:31Z" ; oboInOwl:hasExactSynonym "cellular response to ionising radiation", "cellular response to ionizing radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071479" ; a owl:Class ; rdfs:label "cellular response to ionizing radiation" ; rdfs:subClassOf obo:GO_0010212, obo:GO_0071478 . obo:GO_0071480 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T02:00:50Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "cellular response to gamma ray", "cellular response to gamma-ray photon" ; oboInOwl:id "GO:0071480" ; a owl:Class ; rdfs:label "cellular response to gamma radiation" ; rdfs:subClassOf obo:GO_0010332, obo:GO_0071479 . obo:GO_0071482 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2009-12-18T02:03:49Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071482" ; a owl:Class ; rdfs:label "cellular response to light stimulus" ; rdfs:subClassOf obo:GO_0009416, obo:GO_0071478 . obo:GO_0071684 obo:IAO_0000115 "The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-19T04:23:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071684" ; a owl:Class ; rdfs:label "organism emergence from protective structure" ; rdfs:subClassOf obo:GO_0032501 . obo:GO_0071692 obo:IAO_0000115 "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-02-25T04:00:13Z" ; oboInOwl:hasExactSynonym "protein localisation in extracellular region", "protein localization in extracellular region" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071692" ; a owl:Class ; rdfs:label "protein localization to extracellular region" ; rdfs:subClassOf obo:GO_0008104 . obo:GO_0071695 obo:IAO_0000115 "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-02T11:43:38Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071695" ; a owl:Class ; rdfs:label "anatomical structure maturation" ; rdfs:subClassOf obo:GO_0021700, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048856 ] . obo:GO_0071702 obo:IAO_0000115 "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-08T02:15:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071702" ; a owl:Class ; rdfs:label "organic substance transport" ; rdfs:subClassOf obo:GO_0006810 . obo:GO_0071704 obo:IAO_0000115 "The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-08T03:32:18Z" ; oboInOwl:hasExactSynonym "organic molecular entity metabolic process", "organic molecular entity metabolism", "organic substance metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071704" ; a owl:Class ; rdfs:label "organic substance metabolic process" ; rdfs:subClassOf obo:GO_0008152 . obo:GO_0071705 obo:IAO_0000115 "The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-08T03:56:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071705" ; a owl:Class ; rdfs:label "nitrogen compound transport" ; rdfs:subClassOf obo:GO_0006810 . obo:GO_0071709 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-10T11:19:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071709" ; a owl:Class ; rdfs:label "membrane assembly" ; rdfs:subClassOf obo:GO_0022607, obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044091 ] . obo:GO_0071763 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-03-29T03:59:35Z" ; oboInOwl:hasExactSynonym "nuclear membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "nuclear membrane organization and biogenesis" ; oboInOwl:id "GO:0071763" ; a owl:Class ; rdfs:label "nuclear membrane organization" ; rdfs:subClassOf obo:GO_0061024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006998 ] . obo:GO_0071824 obo:IAO_0000115 "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-08T10:03:26Z" ; oboInOwl:hasExactSynonym "DNA-protein complex subunit organization", "protein-DNA complex subunit organisation", "protein-DNA complex subunit organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071824" ; a owl:Class ; rdfs:label "protein-DNA complex organization" ; rdfs:subClassOf obo:GO_0043933 . obo:GO_0071826 obo:IAO_0000115 "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25143"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-08T10:10:35Z" ; oboInOwl:hasExactSynonym "RNA-protein complex subunit organization", "protein-RNA complex subunit organization", "ribonucleoprotein complex subunit organisation", "ribonucleoprotein complex subunit organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071826" ; a owl:Class ; rdfs:label "protein-RNA complex organization" ; rdfs:subClassOf obo:GO_0043933 . obo:GO_0071840 obo:IAO_0000115 "A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-10T01:39:16Z" ; oboInOwl:hasAlternativeId "GO:0071841" ; oboInOwl:hasExactSynonym "cellular component organisation or biogenesis", "cellular component organisation or biogenesis at cellular level", "cellular component organization or biogenesis at cellular level" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071840" ; oboInOwl:inSubset go:goslim_flybase_ribbon, go:goslim_metagenomics ; a owl:Class ; rdfs:label "cellular component organization or biogenesis" ; rdfs:subClassOf obo:GO_0009987 . obo:GO_0071897 obo:IAO_0000115 "The biosynthetic process resulting in the formation of DNA." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-15T02:14:33Z" ; oboInOwl:hasExactSynonym "DNA anabolism", "DNA biosynthesis", "DNA formation", "DNA synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071897" ; a owl:Class ; rdfs:label "DNA biosynthetic process" ; rdfs:subClassOf obo:GO_0006259, obo:GO_0009059, obo:GO_0034654 . obo:GO_0071944 obo:IAO_0000115 "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-04T01:51:47Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0071944" ; oboInOwl:inSubset go:goslim_flybase_ribbon ; a owl:Class ; rdfs:label "cell periphery" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0071981 obo:IAO_0000115 "The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-21T04:45:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0071981" ; a owl:Class ; rdfs:label "exit from diapause" ; rdfs:subClassOf obo:GO_0022611 . obo:GO_0072347 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-10T01:26:18Z" ; oboInOwl:hasExactSynonym "response to anaesthetic" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072347" ; a owl:Class ; rdfs:label "response to anesthetic" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_0072384 obo:IAO_0000115 "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-12-01T04:59:11Z" ; oboInOwl:hasExactSynonym "microtubule-based organelle localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072384" ; a owl:Class ; rdfs:label "organelle transport along microtubule" ; rdfs:subClassOf obo:GO_0010970, obo:GO_0051656 . obo:GO_0072595 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:09:13Z" ; oboInOwl:hasExactSynonym "maintenance of protein localisation to organelle", "maintenance of protein localization to organelle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072595" ; a owl:Class ; rdfs:label "maintenance of protein localization in organelle" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0032507, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033365 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043226 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043226 ] ) ] . obo:GO_0072656 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:30:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072656" ; a owl:Class ; rdfs:label "maintenance of protein location in mitochondrion" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0070585 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0072662 obo:IAO_0000115 "A process in which a protein is transported to, or maintained at, a location in a peroxisome." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:50:04Z" ; oboInOwl:hasExactSynonym "protein localisation to peroxisome" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072662" ; a owl:Class ; rdfs:label "protein localization to peroxisome" ; rdfs:subClassOf obo:GO_0007031, obo:GO_0033365 . obo:GO_0072664 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:51:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072664" ; a owl:Class ; rdfs:label "maintenance of protein location in peroxisome" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072662 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005777 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005777 ] ) ] . obo:GO_0072665 obo:IAO_0000115 "A process in which a protein is transported to, or maintained at, a location in a vacuole." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:55:35Z" ; oboInOwl:hasExactSynonym "protein localisation to vacuole" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072665" ; a owl:Class ; rdfs:label "protein localization to vacuole" ; rdfs:subClassOf obo:GO_0033365 . obo:GO_0072667 obo:IAO_0000115 "Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-02-14T02:56:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072667" ; a owl:Class ; rdfs:label "maintenance of protein location in vacuole" ; rdfs:subClassOf obo:GO_0072595, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072665 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0045185 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005773 ] ) ] . obo:GO_0072686 obo:IAO_0000115 "A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-07-08T05:08:16Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0072686" ; a owl:Class ; rdfs:label "mitotic spindle" ; rdfs:subClassOf obo:GO_0005819 . obo:GO_0072687 obo:IAO_0000115 "A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-07-08T05:17:08Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0072687" ; a owl:Class ; rdfs:label "meiotic spindle" ; rdfs:subClassOf obo:GO_0005819 . obo:GO_0072710 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-04-11T04:15:42Z" ; oboInOwl:hasExactSynonym "response to HU" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0072710" ; a owl:Class ; rdfs:label "response to hydroxyurea" ; rdfs:subClassOf obo:GO_0010033, obo:GO_1901698 . obo:GO_0080090 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2009-04-22T04:30:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0080090" ; a owl:Class ; rdfs:label "regulation of primary metabolic process" ; rdfs:subClassOf obo:GO_0019222, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044238 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044238 ] ) ] . obo:GO_0080134 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2009-05-06T04:51:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0080134" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "regulation of response to stress" ; rdfs:subClassOf obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006950 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006950 ] ) ] . obo:GO_0080135 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2009-05-06T05:02:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0080135" ; a owl:Class ; rdfs:label "regulation of cellular response to stress" ; rdfs:subClassOf obo:GO_0050794, obo:GO_0080134, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033554 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033554 ] ) ] . obo:GO_0080154 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy)." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2010-09-01T03:44:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0080154" ; a owl:Class ; rdfs:label "regulation of fertilization" ; rdfs:subClassOf obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009566 ] ) ] . obo:GO_0080171 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole." ; oboInOwl:created_by "dhl" ; oboInOwl:creation_date "2011-04-25T04:40:46Z" ; oboInOwl:hasExactSynonym "lytic vacuole organisation" ; oboInOwl:hasNarrowSynonym "lytic vacuolar assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lytic vacuole biogenesis", "lytic vacuole organization and biogenesis" ; oboInOwl:id "GO:0080171" ; a owl:Class ; rdfs:label "lytic vacuole organization" ; rdfs:subClassOf obo:GO_0007033 . obo:GO_0090063 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-08-12T11:33:09Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090063" ; a owl:Class ; rdfs:label "positive regulation of microtubule nucleation" ; rdfs:subClassOf obo:GO_0010968, obo:GO_0031116, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007020 ] ) ] . obo:GO_0090066 obo:IAO_0000115 "Any process that modulates the size of an anatomical structure." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-02T11:00:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090066" ; a owl:Class ; rdfs:label "regulation of anatomical structure size" ; rdfs:subClassOf obo:GO_0065008 . obo:GO_0090068 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-09-09T11:39:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090068" ; a owl:Class ; rdfs:label "positive regulation of cell cycle process" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0045787, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022402 ] ) ] . obo:GO_0090138 obo:IAO_0000115 "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T02:05:00Z" ; oboInOwl:hasExactSynonym "regulation of actin cytoskeleton organisation by cell-cell adhesion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090138" ; a owl:Class ; rdfs:label "regulation of actin cytoskeleton organization by cell-cell adhesion" ; rdfs:subClassOf obo:GO_0032956, obo:GO_0098609 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098609 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030036 ] ) ] . obo:GO_0090139 obo:IAO_0000115 "A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T02:12:19Z" ; oboInOwl:hasExactSynonym "mitochondrial DNA packaging" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090139" ; a owl:Class ; rdfs:label "mitochondrial chromosome packaging" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0051276, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051276 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0090148 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-08T03:06:36Z" ; oboInOwl:hasExactSynonym "membrane scission" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090148" ; a owl:Class ; rdfs:label "membrane fission" ; rdfs:subClassOf obo:GO_0061024 . obo:GO_0090169 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-11T10:17:51Z" ; oboInOwl:hasExactSynonym "regulation of spindle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090169" ; a owl:Class ; rdfs:label "regulation of spindle assembly" ; rdfs:subClassOf obo:GO_0090224, obo:GO_1902115, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051225 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051225 ] ) ] . obo:GO_0090174 obo:IAO_0000115 "The joining of two lipid bilayers to form a single organelle membrane." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2009-12-11T11:44:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090174" ; a owl:Class ; rdfs:label "organelle membrane fusion" ; rdfs:subClassOf obo:GO_0048284, obo:GO_0061025 . obo:GO_0090224 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-13T11:04:53Z" ; oboInOwl:hasExactSynonym "regulation of spindle organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090224" ; a owl:Class ; rdfs:label "regulation of spindle organization" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0070507, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007051 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007051 ] ) ] . obo:GO_0090231 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-20T10:29:43Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090231" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc)." ; rdfs:label "regulation of spindle checkpoint" ; rdfs:subClassOf obo:GO_1901976, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031577 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031577 ] ) ] . obo:GO_0090232 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-20T10:29:43Z" ; oboInOwl:hasNarrowSynonym "spindle checkpoint activation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090232" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:label "positive regulation of spindle checkpoint" ; rdfs:subClassOf obo:GO_0090231, obo:GO_1901978, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031577 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031577 ] ) ] . obo:GO_0090233 obo:IAO_0000115 "Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-20T10:29:43Z" ; oboInOwl:hasNarrowSynonym "spindle checkpoint silencing" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090233" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc)." ; rdfs:label "negative regulation of spindle checkpoint" ; rdfs:subClassOf obo:GO_0090231, obo:GO_1901977, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031577 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031577 ] ) ] . obo:GO_0090235 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-01-20T11:05:55Z" ; oboInOwl:hasExactSynonym "regulation of chromosome congression" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090235" ; a owl:Class ; rdfs:label "regulation of metaphase plate congression" ; rdfs:subClassOf obo:GO_0032879, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051310 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051310 ] ) ] . obo:GO_0090257 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-03T11:48:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090257" ; a owl:Class ; rdfs:label "regulation of muscle system process" ; rdfs:subClassOf obo:GO_0044057, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003012 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0003012 ] ) ] . obo:GO_0090266 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:06:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090266" ; a owl:Class ; rdfs:label "regulation of mitotic cell cycle spindle assembly checkpoint" ; rdfs:subClassOf obo:GO_0007088, obo:GO_0010965, obo:GO_0030071, obo:GO_0033047, obo:GO_1903504, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007094 ] ) ] . obo:GO_0090267 obo:IAO_0000115 "Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-02-05T02:09:44Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090267" ; a owl:Class ; rdfs:label "positive regulation of mitotic cell cycle spindle assembly checkpoint" ; rdfs:subClassOf obo:GO_0090068, obo:GO_0090232, obo:GO_0090266, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007094 ] ) ] . obo:GO_0090296 obo:IAO_0000115 "Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-03-12T03:58:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of mitochondrial DNA synthesis" ; oboInOwl:id "GO:0090296" ; a owl:Class ; rdfs:label "regulation of mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0090329, obo:GO_1901858, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006264 ] ) ] . obo:GO_0090297 obo:IAO_0000115 "Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-03-12T03:58:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of mitochondrial DNA synthesis" ; oboInOwl:id "GO:0090297" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0090296, obo:GO_1901860, obo:GO_2000105, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006264 ] ) ] . obo:GO_0090298 obo:IAO_0000115 "Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-03-12T03:58:25Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of mitochondrial DNA synthesis" ; oboInOwl:id "GO:0090298" ; a owl:Class ; rdfs:label "negative regulation of mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0090296, obo:GO_1901859, obo:GO_2000104, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006264 ] ) ] . obo:GO_0090304 obo:IAO_0000115 "Any cellular metabolic process involving nucleic acids." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/26133"^^xsd:anyURI ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-07T10:18:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090304" ; a owl:Class ; rdfs:label "nucleic acid metabolic process" ; rdfs:subClassOf obo:GO_0006139, obo:GO_0043170 . obo:GO_0090306 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21349"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/24375"^^xsd:anyURI ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-09T11:21:56Z" ; oboInOwl:hasExactSynonym "spindle assembly involved in meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090306" ; a owl:Class ; rdfs:label "meiotic spindle assembly" ; rdfs:subClassOf obo:GO_0000212, obo:GO_0051225, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045132 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140013 ] ) ] . obo:GO_0090307 obo:IAO_0000115 "Mitotic bipolar spindle assembly begins with spindle microtubule nucleation from the separated spindle pole body, includes spindle elongation during prometaphase, and is complete when all kinetochores are stably attached the spindle, and the spindle assembly checkpoint is satisfied." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24375"^^xsd:anyURI ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-09T11:31:28Z" ; oboInOwl:hasExactSynonym "spindle assembly involved in mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090307" ; a owl:Class ; rdfs:label "mitotic spindle assembly" ; rdfs:subClassOf obo:GO_0007052, obo:GO_0051225, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000070 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0051225 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0090316 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-16T03:45:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090316" ; a owl:Class ; rdfs:label "positive regulation of intracellular protein transport" ; rdfs:subClassOf obo:GO_0032388, obo:GO_0033157, obo:GO_0051222, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006886 ] ) ] . obo:GO_0090317 obo:IAO_0000115 "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-04-16T03:45:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090317" ; a owl:Class ; rdfs:label "negative regulation of intracellular protein transport" ; rdfs:subClassOf obo:GO_0032387, obo:GO_0033157, obo:GO_0051224, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006886 ] ) ] . obo:GO_0090325 obo:IAO_0000115 "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-05-14T10:24:29Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090325" ; a owl:Class ; rdfs:label "regulation of locomotion involved in locomotory behavior" ; rdfs:subClassOf obo:GO_0040012, obo:GO_0050795, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0031987 ] ) ] . obo:GO_0090326 obo:IAO_0000115 "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-05-14T10:26:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090326" ; a owl:Class ; rdfs:label "positive regulation of locomotion involved in locomotory behavior" ; rdfs:subClassOf obo:GO_0040017, obo:GO_0048520, obo:GO_0090325, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050789 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0031987 ] ) ] . obo:GO_0090327 obo:IAO_0000115 "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-05-14T10:26:58Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090327" ; a owl:Class ; rdfs:label "negative regulation of locomotion involved in locomotory behavior" ; rdfs:subClassOf obo:GO_0040013, obo:GO_0048521, obo:GO_0090325, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031987 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0031987 ] ) ] . obo:GO_0090329 obo:IAO_0000115 "Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-05-14T10:42:04Z" ; oboInOwl:hasExactSynonym "regulation of DNA-dependent DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090329" ; a owl:Class ; rdfs:label "regulation of DNA-templated DNA replication" ; rdfs:subClassOf obo:GO_0006275, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006261 ] ) ] . obo:GO_0090592 obo:IAO_0000115 "Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2014-06-06T13:54:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090592" ; a owl:Class ; rdfs:label "DNA synthesis involved in DNA replication" ; rdfs:subClassOf obo:GO_0071897, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071897 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006260 ] ) ] . obo:GO_0090615 obo:IAO_0000115 "Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2014-10-24T12:43:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090615" ; a owl:Class ; rdfs:label "mitochondrial mRNA processing" ; rdfs:subClassOf obo:GO_0000963, obo:GO_0006397 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006397 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0090664 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2015-10-21T16:00:30Z" ; oboInOwl:hasExactSynonym "response to crowding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0090664" ; a owl:Class ; rdfs:label "response to high population density" ; rdfs:subClassOf obo:GO_0006950, obo:GO_0032501 . obo:GO_0097014 obo:IAO_0000115 "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-03-23T01:52:31Z" ; oboInOwl:hasExactSynonym "cilium plasm" ; oboInOwl:hasNarrowSynonym "microtubule-based flagellar matrix", "microtubule-based flagellum matrix" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "cilial cytoplasm", "ciliary cytoplasm", "cilium cytoplasm", "microtubule-based flagellar cytoplasm", "microtubule-based flagellum cytoplasm" ; oboInOwl:id "GO:0097014" ; a owl:Class ; rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term \"ciliary plasm\" is not linked to \"cytoplasm\"." ; rdfs:label "ciliary plasm" ; rdfs:subClassOf obo:GO_0032838, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005929 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005929 ] ) ] . obo:GO_0097060 obo:IAO_0000115 "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-06-07T11:22:09Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097060" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic membrane" ; rdfs:subClassOf obo:GO_0098590, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0098590 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0097091 obo:IAO_0000115 "The process that results in grouping synaptic vesicles in presynaptic structures." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/163"^^xsd:anyURI ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-07-04T01:48:24Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097091" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle clustering" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0097479, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099504 ] . obo:GO_0097164 obo:IAO_0000115 "The chemical reactions and pathways involving the ammonium ion." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-09-28T04:21:30Z" ; oboInOwl:hasExactSynonym "ammonium ion metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "ammonium metabolic process" ; oboInOwl:id "GO:0097164" ; a owl:Class ; rdfs:label "ammonium ion metabolic process" ; rdfs:subClassOf obo:GO_0006807 . obo:GO_0097190 obo:IAO_0000115 "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-23T09:30:23Z" ; oboInOwl:hasAlternativeId "GO:0008624" ; oboInOwl:hasExactSynonym "apoptotic signalling pathway", "induction of apoptosis by extracellular signals" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097190" ; a owl:Class ; rdfs:comment "This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways." ; rdfs:label "apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_0007165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006915 ] . obo:GO_0097193 obo:IAO_0000115 "The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP)." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-23T09:40:50Z" ; oboInOwl:hasAlternativeId "GO:0008629" ; oboInOwl:hasExactSynonym "intrinsic apoptotic pathway", "intrinsic apoptotic signalling pathway", "mitochondrial-mediated apoptotic pathway" ; oboInOwl:hasNarrowSynonym "intrinsic apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "induction of apoptosis by intracellular signals" ; oboInOwl:id "GO:0097193" ; a owl:Class ; rdfs:comment "The signals that start intrinsic apoptosis may come from extracellular sources (e.g. oxidative stress, UV exposure), but the reception of the signal and thus the signaling pathway start inside the cell (as a result of DNA damage, redox imbalance, etc.). Examples are ZPR9 (ZNF622) and ASK1 (MAP3K5) (UniProt symbols Q969S3 and Q99683) in PMID:21771788. A diagram of the intrinsic apoptotic pathway including examples of molecular players can be found in Figure 2 in PMID:21760595." ; rdfs:label "intrinsic apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_0035556, obo:GO_0097190 . obo:GO_0097435 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-27T15:46:25Z" ; oboInOwl:hasAlternativeId "GO:0043206" ; oboInOwl:hasNarrowSynonym "extracellular fibril organisation", "extracellular fibril organization", "extracellular fibril organization and biogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "fibril organisation", "fibril organization" ; oboInOwl:id "GO:0097435" ; a owl:Class ; rdfs:label "supramolecular fiber organization" ; rdfs:subClassOf obo:GO_0016043 . obo:GO_0097447 obo:IAO_0000115 "The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-12-17T12:31:49Z" ; oboInOwl:hasDbXref "NIF_Subcellular:sao172297168" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097447" ; a owl:Class ; rdfs:label "dendritic tree" ; rdfs:subClassOf obo:GO_0043005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0036477 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0030425 ] . obo:GO_0097479 obo:IAO_0000115 "Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-05-22T14:29:55Z" ; oboInOwl:hasExactSynonym "establishment and maintenance of synaptic vesicle localization", "establishment and maintenance of synaptic vesicle position", "synaptic vesicle localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097479" ; a owl:Class ; rdfs:label "synaptic vesicle localization" ; rdfs:subClassOf obo:GO_0051648 . obo:GO_0097485 obo:IAO_0000115 "The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/25417"^^xsd:anyURI ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-07-08T13:32:37Z" ; oboInOwl:hasExactSynonym "neuron process guidance", "neuron protrusion guidance", "neuronal cell projection guidance" ; oboInOwl:hasNarrowSynonym "neurite guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0097485" ; a owl:Class ; rdfs:label "neuron projection guidance" ; rdfs:subClassOf obo:GO_0031175, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048812 ] . obo:GO_0097708 obo:IAO_0000115 "Any vesicle that is part of the intracellular region." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-03-29T17:39:45Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0097708" ; a owl:Class ; rdfs:label "intracellular vesicle" ; rdfs:subClassOf obo:GO_0031982, obo:GO_0043231 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0031982 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005622 ] ) ] . obo:GO_0098542 obo:IAO_0000115 "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22173"^^xsd:anyURI ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2013-11-11T12:59:11Z" ; oboInOwl:hasAlternativeId "GO:0009814" ; oboInOwl:hasNarrowSynonym "defence response incompatible interaction", "defence response to pathogen, incompatible interaction", "defense response, incompatible interaction", "resistance response to pathogen" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098542" ; oboInOwl:inSubset go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "defense response to other organism" ; rdfs:subClassOf obo:GO_0006952, obo:GO_0051707 . obo:GO_0098590 obo:IAO_0000115 "A membrane that is a (regional) part of the plasma membrane." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2014-03-06T11:55:32Z" ; oboInOwl:hasExactSynonym "region of plasma membrane" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098590" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass." ; rdfs:label "plasma membrane region" ; rdfs:subClassOf obo:GO_0016020, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016020 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0098609 obo:IAO_0000115 "The attachment of one cell to another cell via adhesion molecules." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2014-04-16T13:40:03Z" ; oboInOwl:hasAlternativeId "GO:0016337" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "single organismal cell-cell adhesion" ; oboInOwl:id "GO:0098609" ; a owl:Class ; rdfs:label "cell-cell adhesion" ; rdfs:subClassOf obo:GO_0007155 . obo:GO_0098631 obo:IAO_0000115 "The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22959"^^xsd:anyURI ; oboInOwl:hasExactSynonym "cell adhesion molecule", "protein binding involved in cell adhesion" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0098631" ; oboInOwl:inSubset go:goslim_generic, go:prokaryote_subset ; a owl:Class ; rdfs:label "cell adhesion mediator activity" ; rdfs:subClassOf obo:GO_0050839, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007155 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005488 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007155 ] ) ] . obo:GO_0098632 obo:IAO_0000115 "The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell." ; oboInOwl:hasExactSynonym "cell-cell adhesion molecule", "protein binding involved in cell-cell adhesion" ; oboInOwl:hasOBONamespace "molecular_function" ; oboInOwl:id "GO:0098632" ; a owl:Class ; rdfs:label "cell-cell adhesion mediator activity" ; rdfs:subClassOf obo:GO_0098631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098609 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005515 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098609 ] ) ] . obo:GO_0098657 obo:IAO_0000115 "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis." ; oboInOwl:hasBroadSynonym "uptake" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098657" ; a owl:Class ; rdfs:label "import into cell" ; rdfs:subClassOf obo:GO_0006810 . obo:GO_0098687 obo:IAO_0000115 "Any subdivision of a chromosome along its length." ; oboInOwl:hasExactSynonym "chromosome region" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098687" ; a owl:Class ; rdfs:comment "Chromosomal regions include parts that are not part of the chromatin. Examples include the kinetochore." ; rdfs:label "chromosomal region" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005694 ] . obo:GO_0098693 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-03-21T16:06:48Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098693" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of synaptic vesicle cycle" ; rdfs:subClassOf obo:GO_0060627, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099504 ] ) ] . obo:GO_0098762 obo:IAO_0000115 "One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098762" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiotic cell cycle phase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022403 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0098763 obo:IAO_0000115 "One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098763" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "mitotic cell cycle phase" ; rdfs:subClassOf obo:GO_0022403, [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0022403 [ a owl:Restriction ; owl:onProperty obo:RO_0002092 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0098764 obo:IAO_0000115 "A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098764" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during)." ; rdfs:label "meiosis I cell cycle phase" ; rdfs:subClassOf obo:GO_0098762 . obo:GO_0098793 obo:IAO_0000115 "The part of a synapse that is part of the presynaptic cell." ; oboInOwl:hasExactSynonym "presynaptic terminal" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098793" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynapse" ; rdfs:subClassOf obo:GO_0110165, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0045202 ] . obo:GO_0098796 obo:IAO_0000115 "Any protein complex that is part of a membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098796" ; oboInOwl:inSubset go:goslim_metagenomics ; a owl:Class ; rdfs:label "membrane protein complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0016020 ] ) ] . obo:GO_0098797 obo:IAO_0000115 "Any protein complex that is part of the plasma membrane." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0098797" ; a owl:Class ; rdfs:label "plasma membrane protein complex" ; rdfs:subClassOf obo:GO_0098796, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005886 ] ) ] . obo:GO_0098798 obo:IAO_0000115 "A protein complex that is part of a mitochondrion." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "mitochondrial protein complex" ; oboInOwl:id "GO:0098798" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC." ; rdfs:label "mitochondrial protein-containing complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0098813 obo:IAO_0000115 "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098813" ; a owl:Class ; rdfs:label "nuclear chromosome segregation" ; rdfs:subClassOf obo:GO_0007059 . obo:GO_0098916 obo:IAO_0000115 "Cell-cell signaling from pre to post-synapse, across the synaptic cleft." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098916" ; a owl:Class ; rdfs:label "anterograde trans-synaptic signaling" ; rdfs:subClassOf obo:GO_0099537 . obo:GO_0098930 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules in axons." ; oboInOwl:hasDbXref "Wikipedia:Axoplasmic_transport" ; oboInOwl:hasExactSynonym "axon cargo transport", "axoplasmic transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0098930" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "axonal transport" ; rdfs:subClassOf obo:GO_0008088, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0030424 ] . obo:GO_0099003 obo:IAO_0000115 "Any vesicle-mediated transport that occurs in a synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099003" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "vesicle-mediated transport in synapse" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0016192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0016192 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0099024 obo:IAO_0000115 "An infolding of the plasma membrane." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099024" ; a owl:Class ; rdfs:label "plasma membrane invagination" ; rdfs:subClassOf obo:GO_0010324 . obo:GO_0099080 obo:IAO_0000115 "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099080" ; a owl:Class ; rdfs:label "supramolecular complex" ; rdfs:subClassOf obo:GO_0110165 . obo:GO_0099081 obo:IAO_0000115 "A polymeric supramolecular structure." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099081" ; a owl:Class ; rdfs:label "supramolecular polymer" ; rdfs:subClassOf obo:GO_0099080 . obo:GO_0099098 obo:IAO_0000115 "The movement of a cellular component as a result of microtubule polymerization." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099098" ; a owl:Class ; rdfs:label "microtubule polymerization based movement" ; rdfs:subClassOf obo:GO_0007018, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0046785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007018 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0046785 ] ) ] . obo:GO_0099111 obo:IAO_0000115 "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099111" ; a owl:Class ; rdfs:label "microtubule-based transport" ; rdfs:subClassOf obo:GO_0006810 . obo:GO_0099143 obo:IAO_0000115 "The actin cytoskeleton that is part of a presynapse." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-06-09T18:36:19Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099143" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic actin cytoskeleton" ; rdfs:subClassOf obo:GO_0015629, obo:GO_0099569 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0015629 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099171 obo:IAO_0000115 "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-09-11T17:09:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099171" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic modulation of chemical synaptic transmission" ; rdfs:subClassOf obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050804 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099177 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of trans-synaptic signaling." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099177" ; a owl:Class ; rdfs:label "regulation of trans-synaptic signaling" ; rdfs:subClassOf obo:GO_0010646, obo:GO_0023051, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099537 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0099537 ] ) ] . obo:GO_0099500 obo:IAO_0000115 "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099500" ; a owl:Class ; rdfs:label "vesicle fusion to plasma membrane" ; rdfs:subClassOf obo:GO_0006906, obo:GO_0140029 . obo:GO_0099503 obo:IAO_0000115 "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099503" ; oboInOwl:inSubset go:goslim_drosophila ; a owl:Class ; rdfs:label "secretory vesicle" ; rdfs:subClassOf obo:GO_0031410 . obo:GO_0099504 obo:IAO_0000115 "A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099504" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle cycle" ; rdfs:subClassOf obo:GO_0051649, obo:GO_0099003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] . obo:GO_0099512 obo:IAO_0000115 "A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure." ; oboInOwl:hasAlternativeId "GO:0043205" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:hasRelatedSynonym "fibril" ; oboInOwl:id "GO:0099512" ; a owl:Class ; rdfs:label "supramolecular fiber" ; rdfs:subClassOf obo:GO_0099081 . obo:GO_0099513 obo:IAO_0000115 "A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099513" ; a owl:Class ; rdfs:label "polymeric cytoskeletal fiber" ; rdfs:subClassOf obo:GO_0099512, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005856 ] . obo:GO_0099514 obo:IAO_0000115 "The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099514" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle cytoskeletal transport" ; rdfs:subClassOf obo:GO_0048489, obo:GO_0099518 . obo:GO_0099517 obo:IAO_0000115 "The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099517" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic vesicle transport along microtubule" ; rdfs:subClassOf obo:GO_0047496, obo:GO_0099514 . obo:GO_0099518 obo:IAO_0000115 "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins." ; oboInOwl:hasExactSynonym "cytoskeletal fiber-based vesicle localization", "vesicle cytoskeletal transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099518" ; a owl:Class ; rdfs:label "vesicle cytoskeletal trafficking" ; rdfs:subClassOf obo:GO_0030705, obo:GO_0051650 . obo:GO_0099522 obo:IAO_0000115 "Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol." ; oboInOwl:hasExactSynonym "region of cytosol" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099522" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "cytosolic region" ; rdfs:subClassOf obo:GO_0005829, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005829 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005829 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005829 ] ) ] . obo:GO_0099523 obo:IAO_0000115 "The region of the cytosol consisting of all cytosol that is part of the presynapse." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099523" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic cytosol" ; rdfs:subClassOf obo:GO_0099522, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005829 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005829 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099531 obo:IAO_0000115 "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099531" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic process involved in chemical synaptic transmission" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0050877, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007268 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0050877 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0007268 ] [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099536 obo:IAO_0000115 "Cell-cell signaling to, from or within a synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099536" ; oboInOwl:inSubset go:goslim_drosophila, go:goslim_synapse ; a owl:Class ; rdfs:label "synaptic signaling" ; rdfs:subClassOf obo:GO_0007267, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0007267 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0099537 obo:IAO_0000115 "Cell-cell signaling in either direction across the synaptic cleft." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099537" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "trans-synaptic signaling" ; rdfs:subClassOf obo:GO_0099536 . obo:GO_0099547 obo:IAO_0000115 "Any process that modulates synaptic transmission by regulating translation occurring at the synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099547" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of translation at synapse, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0050804, obo:GO_0140243 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099550 obo:IAO_0000115 "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099550" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "trans-synaptic signaling, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0050804, obo:GO_0099537 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0099537 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099568 obo:IAO_0000115 "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099568" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "cytoplasmic region" ; rdfs:subClassOf obo:GO_0005737, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005737 ] ) ] . obo:GO_0099569 obo:IAO_0000115 "The portion of the cytoskeleton contained within the presynapse." ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099569" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "presynaptic cytoskeleton" ; rdfs:subClassOf obo:GO_0005856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005856 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0099575 obo:IAO_0000115 "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099575" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of protein catabolic process at presynapse, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0042176, obo:GO_0099171 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042176 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099577 obo:IAO_0000115 "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099577" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of translation at presynapse, modulating synaptic transmission" ; rdfs:subClassOf obo:GO_0099171, obo:GO_0099547, obo:GO_0140244 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0099636 obo:IAO_0000115 "The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains." ; oboInOwl:hasDbXref "Wikipedia:Cytoplasmic_streaming" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099636" ; a owl:Class ; rdfs:label "cytoplasmic streaming" ; rdfs:subClassOf obo:GO_0016482 . obo:GO_0099643 obo:IAO_0000115 "Any signal release from a synapse." ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0099643" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "signal release from synapse" ; rdfs:subClassOf obo:GO_0023061, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0099536 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0023061 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0099738 obo:IAO_0000115 "The complete extent of cell cortex that underlies some some region of the plasma membrane." ; oboInOwl:hasExactSynonym "perimembrane region" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0099738" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "cell cortex region" ; rdfs:subClassOf obo:GO_0005938, obo:GO_0099568, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005938 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005938 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005938 ] ) ] . obo:GO_0101024 obo:IAO_0000115 "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19949"^^xsd:anyURI ; oboInOwl:hasExactSynonym "nuclear membrane organization involved in mitotic nuclear division" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0101024" ; a owl:Class ; rdfs:comment "This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown." ; rdfs:label "mitotic nuclear membrane organization" ; rdfs:subClassOf obo:GO_0071763, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071763 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0140014 ] ) ] . obo:GO_0104004 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus." ; oboInOwl:created_by "dos" ; oboInOwl:creation_date "2017-02-17T16:02:42Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0104004" ; a owl:Class ; rdfs:label "cellular response to environmental stimulus" ; rdfs:subClassOf obo:GO_0051716 . obo:GO_0106030 obo:IAO_0000115 "The collection of neuronal projections into a bundle of rods, known as a fascicle." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2017-06-26T19:43:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0106030" ; a owl:Class ; rdfs:label "neuron projection fasciculation" ; rdfs:subClassOf obo:GO_0031175 . obo:GO_0106049 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the cellular response to osmotic stress." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2017-08-04T14:53:47Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0106049" ; a owl:Class ; rdfs:label "regulation of cellular response to osmotic stress" ; rdfs:subClassOf obo:GO_0047484, obo:GO_0080135, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071470 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071470 ] ) ] . obo:GO_0110028 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic spindle organization." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-07-06T14:14:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110028" ; a owl:Class ; rdfs:label "positive regulation of mitotic spindle organization" ; rdfs:subClassOf obo:GO_0045931, obo:GO_0051495, obo:GO_0060236, obo:GO_0090068, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007052 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007052 ] ) ] . obo:GO_0110029 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2017-07-12T18:47:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110029" ; a owl:Class ; rdfs:label "negative regulation of meiosis I" ; rdfs:subClassOf obo:GO_0045835, obo:GO_0060631, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007127 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007127 ] ) ] . obo:GO_0110165 obo:IAO_0000115 "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24200"^^xsd:anyURI ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2019-08-12T18:01:37Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0110165" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pir ; a owl:Class ; rdfs:label "cellular anatomical entity" ; rdfs:subClassOf obo:GO_0005575 . obo:GO_0110166 obo:IAO_0000115 "Any DNA biosynthetic process that is involved in mitochondrial DNA replication." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17716"^^xsd:anyURI ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2020-03-18T13:30:39Z" ; oboInOwl:hasExactSynonym "DNA biosynthetic process involved in mitochondrial DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0110166" ; a owl:Class ; rdfs:label "DNA synthesis involved in mitochondrial DNA replication" ; rdfs:subClassOf obo:GO_0032042, obo:GO_0090592, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006264 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071897 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006264 ] ) ] . obo:GO_0120025 obo:IAO_0000115 "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13193"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-03-21T17:26:07Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0120025" ; a owl:Class ; rdfs:label "plasma membrane bounded cell projection" ; rdfs:subClassOf obo:GO_0042995, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0098590 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0042995 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0098590 ] ) ] . obo:GO_0120035 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-26T16:02:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120035" ; a owl:Class ; rdfs:label "regulation of plasma membrane bounded cell projection organization" ; rdfs:subClassOf obo:GO_0031344, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0120036 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0120036 ] ) ] . obo:GO_0120036 obo:IAO_0000115 "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-26T16:07:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120036" ; a owl:Class ; rdfs:label "plasma membrane bounded cell projection organization" ; rdfs:subClassOf obo:GO_0030030 . obo:GO_0120039 obo:IAO_0000115 "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-04-28T23:39:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120039" ; a owl:Class ; rdfs:label "plasma membrane bounded cell projection morphogenesis" ; rdfs:subClassOf obo:GO_0048858 . obo:GO_0120111 obo:IAO_0000115 "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2017-11-01T18:58:12Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0120111" ; a owl:Class ; rdfs:label "neuron projection cytoplasm" ; rdfs:subClassOf obo:GO_0032838, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043005 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0043005 ] ) ] . obo:GO_0120305 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/20524"^^xsd:anyURI ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2021-02-09T19:37:35Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0120305" ; a owl:Class ; rdfs:label "regulation of pigmentation" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043473 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043473 ] ) ] . obo:GO_0140013 obo:IAO_0000115 "One of the two nuclear divisions that occur as part of the meiotic cell cycle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19910"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2017-03-23T09:40:00Z" ; oboInOwl:hasExactSynonym "meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140013" ; oboInOwl:inSubset go:goslim_generic ; a owl:Class ; rdfs:label "meiotic nuclear division" ; rdfs:subClassOf obo:GO_0000280, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000280 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_0140014 obo:IAO_0000115 "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19910"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2017-03-23T14:44:23Z" ; oboInOwl:hasExactSynonym "mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140014" ; oboInOwl:inSubset go:goslim_chembl, go:goslim_generic ; a owl:Class ; rdfs:label "mitotic nuclear division" ; rdfs:subClassOf obo:GO_0000280, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000280 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_0140029 obo:IAO_0000115 "The cellular processes that contribute to exocytosis." ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2017-05-15T13:20:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140029" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "exocytic process" ; rdfs:subClassOf obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006887 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0006887 ] ) ] . obo:GO_0140053 obo:IAO_0000115 "The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form." ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2017-06-26T10:57:45Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140053" ; oboInOwl:inSubset go:goslim_generic, go:goslim_pombe ; a owl:Class ; rdfs:label "mitochondrial gene expression" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0010467, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0010467 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_0140236 obo:IAO_0000115 "Translation that occurs at the presynapse." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/216"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2018-07-13T13:00:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140236" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "translation at presynapse" ; rdfs:subClassOf obo:GO_0140241, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006412 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0140237 obo:IAO_0000115 "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/216"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2018-07-13T13:07:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140237" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "translation at presynapse, modulating chemical synaptic transmission" ; rdfs:subClassOf obo:BFO_0000015, obo:GO_0140236, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006412 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007268 ] ) ] . obo:GO_0140238 obo:IAO_0000115 "A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/230"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2018-07-15T07:33:55Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140238" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "presynaptic endocytosis" ; rdfs:subClassOf obo:GO_0006897, obo:GO_0051649, obo:GO_0099003, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006897 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] . obo:GO_0140241 obo:IAO_0000115 "Translation that occurs at the synapse." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/210"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2018-07-15T09:23:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140241" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "translation at synapse" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0006412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006412 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ) ] . obo:GO_0140243 obo:IAO_0000115 "Any process that regulates translation occurring at the synapse." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/210"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2018-07-15T09:38:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140243" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of translation at synapse" ; rdfs:subClassOf obo:GO_0006417, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0045202 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0140244 obo:IAO_0000115 "Any process that regulates translation occurring at the presynapse." ; obo:IAO_0000233 "https://github.com/geneontology/synapse/issues/210"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2018-07-15T09:38:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140244" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua." ; rdfs:label "regulation of translation at presynapse" ; rdfs:subClassOf obo:GO_0140243, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_0140253 obo:IAO_0000115 "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/15939"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2018-08-13T18:38:18Z" ; oboInOwl:hasBroadSynonym "cell fusion" ; oboInOwl:hasExactSynonym "cell cell fusion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140253" ; a owl:Class ; rdfs:label "cell-cell fusion" ; rdfs:subClassOf obo:GO_0009987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:GO_0045026 ] . obo:GO_0140352 obo:IAO_0000115 "The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis." ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2019-05-22T11:20:45Z" ; oboInOwl:hasBroadSynonym "efflux" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140352" ; a owl:Class ; rdfs:label "export from cell" ; rdfs:subClassOf obo:GO_0006810, obo:GO_0009987 . obo:GO_0140499 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of negative regulation of mitotic spindle assembly checkpoint signaling." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19818"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2020-07-22T15:44:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140499" ; a owl:Class ; rdfs:label "negative regulation of mitotic spindle assembly checkpoint signaling" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0045842, obo:GO_0062033, obo:GO_0090233, obo:GO_0090266, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007094 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007094 ] ) ] . obo:GO_0140513 obo:IAO_0000115 "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus." ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2020-09-09T05:12:38Z" ; oboInOwl:hasExactSynonym "nuclear complex" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0140513" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "nuclear protein-containing complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005634 ] ) ] . obo:GO_0140534 obo:IAO_0000115 "A protein complex that is part of an endoplasmic reticulum." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/19952"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2020-10-28T12:14:12Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:0140534" ; a owl:Class ; rdfs:label "endoplasmic reticulum protein-containing complex" ; rdfs:subClassOf obo:GO_0032991, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005783 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0032991 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0005783 ] ) ] . obo:GO_0140694 obo:IAO_0000115 "The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21939"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2021-08-09T15:30:06Z" ; oboInOwl:hasExactSynonym "non-membrane-bounded organelle formation", "non-membrane-enclosed organelle assembly", "non-membrane-enclosed organelle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140694" ; a owl:Class ; rdfs:label "non-membrane-bounded organelle assembly" ; rdfs:subClassOf obo:GO_0070925 . obo:GO_0140975 obo:IAO_0000115 "The disruption of a cellular component of another organism, leading to damage or temporary subversion of that structure. In some cases this can cause malfunctioning of the cells and death of the target organism." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/24072"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/24127"^^xsd:anyURI, "https://github.com/geneontology/go-ontology/issues/25514"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2022-09-23T13:20:49Z" ; oboInOwl:hasBroadSynonym "disruption of cellular component of another organism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0140975" ; a owl:Class ; rdfs:label "disruption of cellular anatomical structure in another organism" ; rdfs:subClassOf obo:GO_0141060 . obo:GO_0141060 obo:IAO_0000115 "The disruption of an anatomical structure of another organism, leading to damage or temporary subversion of that structure." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/25514"^^xsd:anyURI ; oboInOwl:created_by "pg" ; oboInOwl:creation_date "2023-06-07T14:40:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:0141060" ; a owl:Class ; rdfs:label "disruption of anatomical structure in another organism" ; rdfs:subClassOf obo:GO_0044419 . obo:GO_1900006 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of dendrite development." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2012-01-09T10:41:31Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "up regulation of dendrite development" ; oboInOwl:id "GO:1900006" ; a owl:Class ; rdfs:label "positive regulation of dendrite development" ; rdfs:subClassOf obo:GO_0010976, obo:GO_0050773, obo:GO_0051094, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016358 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016358 ] ) ] . obo:GO_1900063 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of peroxisome organization." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-01-26T01:49:05Z" ; oboInOwl:hasExactSynonym "regulation of peroxisome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of peroxisome organization and biogenesis", "regulation of peroxisome-assembly ATPase activity" ; oboInOwl:id "GO:1900063" ; a owl:Class ; rdfs:label "regulation of peroxisome organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007031 ] ) ] . obo:GO_1900064 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of peroxisome organization." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2012-01-26T01:49:09Z" ; oboInOwl:hasExactSynonym "positive regulation of peroxisome organisation", "up regulation of peroxisome organisation", "up-regulation of peroxisome organisation", "upregulation of peroxisome organisation" ; oboInOwl:hasNarrowSynonym "activation of peroxisome organisation", "activation of peroxisome organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of peroxisome organization and biogenesis", "activation of peroxisome-assembly ATPase activity", "positive regulation of peroxisome organization and biogenesis", "positive regulation of peroxisome-assembly ATPase activity", "up regulation of peroxisome organization", "up regulation of peroxisome organization and biogenesis", "up regulation of peroxisome-assembly ATPase activity", "up-regulation of peroxisome organization", "up-regulation of peroxisome organization and biogenesis", "up-regulation of peroxisome-assembly ATPase activity", "upregulation of peroxisome organization", "upregulation of peroxisome organization and biogenesis", "upregulation of peroxisome-assembly ATPase activity" ; oboInOwl:id "GO:1900064" ; a owl:Class ; rdfs:label "positive regulation of peroxisome organization" ; rdfs:subClassOf obo:GO_0010638, obo:GO_1900063, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007031 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007031 ] ) ] . obo:GO_1900073 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-01-26T10:14:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900073" ; a owl:Class ; rdfs:label "regulation of neuromuscular synaptic transmission" ; rdfs:subClassOf obo:GO_0050804, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007274 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007274 ] ) ] . obo:GO_1900074 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-01-26T10:14:18Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of neuromuscular synaptic transmission", "down-regulation of neuromuscular synaptic transmission", "downregulation of neuromuscular synaptic transmission", "inhibition of neuromuscular synaptic transmission" ; oboInOwl:id "GO:1900074" ; a owl:Class ; rdfs:label "negative regulation of neuromuscular synaptic transmission" ; rdfs:subClassOf obo:GO_0050805, obo:GO_1900073, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007274 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007274 ] ) ] . obo:GO_1900075 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-01-26T10:14:22Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of neuromuscular synaptic transmission", "up regulation of neuromuscular synaptic transmission", "up-regulation of neuromuscular synaptic transmission", "upregulation of neuromuscular synaptic transmission" ; oboInOwl:id "GO:1900075" ; a owl:Class ; rdfs:label "positive regulation of neuromuscular synaptic transmission" ; rdfs:subClassOf obo:GO_0050806, obo:GO_1900073, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007274 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007274 ] ) ] . obo:GO_1900087 obo:IAO_0000115 "Any signaling pathway that increases or activates a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle." ; oboInOwl:created_by "rph" ; oboInOwl:creation_date "2012-02-08T12:24:39Z" ; oboInOwl:hasExactSynonym "up regulation of G1/S transition of mitotic cell cycle", "up-regulation of G1/S transition of mitotic cell cycle", "upregulation of G1/S transition of mitotic cell cycle" ; oboInOwl:hasNarrowSynonym "activation of G1/S transition of mitotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900087" ; a owl:Class ; rdfs:label "positive regulation of G1/S transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_1901992, obo:GO_1902808, obo:GO_2000045, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000082 ] ) ] . obo:GO_1900101 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response." ; oboInOwl:created_by "ppm" ; oboInOwl:creation_date "2012-02-15T11:15:27Z" ; oboInOwl:hasExactSynonym "regulation of ER unfolded protein response", "regulation of erUPR" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of SREBP-mediated signalling pathway" ; oboInOwl:id "GO:1900101" ; a owl:Class ; rdfs:label "regulation of endoplasmic reticulum unfolded protein response" ; rdfs:subClassOf obo:GO_0009966, obo:GO_1905897, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030968 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030968 ] ) ] . obo:GO_1900102 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response." ; oboInOwl:created_by "ppm" ; oboInOwl:creation_date "2012-02-15T11:15:31Z" ; oboInOwl:hasExactSynonym "down regulation of ER unfolded protein response", "down regulation of endoplasmic reticulum unfolded protein response", "down regulation of erUPR", "down-regulation of ER unfolded protein response", "down-regulation of endoplasmic reticulum unfolded protein response", "down-regulation of erUPR", "downregulation of ER unfolded protein response", "downregulation of endoplasmic reticulum unfolded protein response", "downregulation of erUPR", "inhibition of ER unfolded protein response", "inhibition of erUPR", "negative regulation of ER unfolded protein response", "negative regulation of erUPR" ; oboInOwl:hasNarrowSynonym "inhibition of endoplasmic reticulum unfolded protein response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of SREBP-mediated signalling pathway", "down-regulation of SREBP-mediated signalling pathway", "downregulation of SREBP-mediated signalling pathway", "inhibition of SREBP-mediated signalling pathway", "negative regulation of SREBP-mediated signalling pathway" ; oboInOwl:id "GO:1900102" ; a owl:Class ; rdfs:label "negative regulation of endoplasmic reticulum unfolded protein response" ; rdfs:subClassOf obo:GO_0009968, obo:GO_1900101, obo:GO_1903573, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030968 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030968 ] ) ] . obo:GO_1900103 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response." ; oboInOwl:created_by "ppm" ; oboInOwl:creation_date "2012-02-15T11:15:35Z" ; oboInOwl:hasExactSynonym "activation of ER unfolded protein response", "activation of erUPR", "positive regulation of ER unfolded protein response", "positive regulation of erUPR", "up regulation of ER unfolded protein response", "up regulation of endoplasmic reticulum unfolded protein response", "up regulation of erUPR", "up-regulation of ER unfolded protein response", "up-regulation of endoplasmic reticulum unfolded protein response", "up-regulation of erUPR", "upregulation of ER unfolded protein response", "upregulation of endoplasmic reticulum unfolded protein response", "upregulation of erUPR" ; oboInOwl:hasNarrowSynonym "activation of endoplasmic reticulum unfolded protein response" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of SREBP-mediated signalling pathway", "positive regulation of SREBP-mediated signalling pathway", "up regulation of SREBP-mediated signalling pathway", "up-regulation of SREBP-mediated signalling pathway", "upregulation of SREBP-mediated signalling pathway" ; oboInOwl:id "GO:1900103" ; a owl:Class ; rdfs:label "positive regulation of endoplasmic reticulum unfolded protein response" ; rdfs:subClassOf obo:GO_0009967, obo:GO_1900101, obo:GO_1905898, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030968 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030968 ] ) ] . obo:GO_1900120 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-02-22T11:40:53Z" ; oboInOwl:hasNarrowSynonym "regulation of receptor ligand" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900120" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "regulation of receptor binding" ; rdfs:subClassOf obo:GO_0043393, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0005102 ] ) ] . obo:GO_1900121 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-02-22T11:40:57Z" ; oboInOwl:hasExactSynonym "down regulation of receptor binding", "down-regulation of receptor binding", "downregulation of receptor binding" ; oboInOwl:hasNarrowSynonym "inhibition of receptor binding", "inhibition of receptor ligand" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of receptor-associated protein activity" ; oboInOwl:id "GO:1900121" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "negative regulation of receptor binding" ; rdfs:subClassOf obo:GO_0032091, obo:GO_1900120, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0005102 ] ) ] . obo:GO_1900122 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-02-22T11:41:00Z" ; oboInOwl:hasExactSynonym "up regulation of receptor binding", "upregulation of receptor binding" ; oboInOwl:hasNarrowSynonym "activation of receptor binding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900122" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "positive regulation of receptor binding" ; rdfs:subClassOf obo:GO_0032092, obo:GO_1900120, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0005102 ] ) ] . obo:GO_1900180 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein localization to nucleus." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-03-12T01:23:44Z" ; oboInOwl:hasExactSynonym "regulation of protein localisation to nucleus", "regulation of protein localization in cell nucleus", "regulation of protein localization in nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900180" ; a owl:Class ; rdfs:label "regulation of protein localization to nucleus" ; rdfs:subClassOf obo:GO_0032880, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034504 ] ) ] . obo:GO_1900181 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-03-12T01:23:48Z" ; oboInOwl:hasExactSynonym "down regulation of protein localisation to nucleus", "down regulation of protein localization in cell nucleus", "down regulation of protein localization in nucleus", "down regulation of protein localization to nucleus", "down-regulation of protein localisation to nucleus", "down-regulation of protein localization in cell nucleus", "down-regulation of protein localization in nucleus", "down-regulation of protein localization to nucleus", "downregulation of protein localisation to nucleus", "downregulation of protein localization in cell nucleus", "downregulation of protein localization in nucleus", "downregulation of protein localization to nucleus", "negative regulation of protein localisation to nucleus", "negative regulation of protein localization in cell nucleus", "negative regulation of protein localization in nucleus" ; oboInOwl:hasNarrowSynonym "inhibition of protein localisation to nucleus", "inhibition of protein localization in cell nucleus", "inhibition of protein localization in nucleus", "inhibition of protein localization to nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900181" ; a owl:Class ; rdfs:label "negative regulation of protein localization to nucleus" ; rdfs:subClassOf obo:GO_1900180, obo:GO_1903828, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034504 ] ) ] . obo:GO_1900182 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-03-12T01:23:52Z" ; oboInOwl:hasExactSynonym "activation of protein localization in nucleus", "positive regulation of protein localisation to nucleus", "positive regulation of protein localization in cell nucleus", "positive regulation of protein localization in nucleus", "up regulation of protein localisation to nucleus", "up regulation of protein localization in cell nucleus", "up regulation of protein localization in nucleus", "up regulation of protein localization to nucleus", "up-regulation of protein localisation to nucleus", "up-regulation of protein localization in cell nucleus", "up-regulation of protein localization in nucleus", "up-regulation of protein localization to nucleus", "upregulation of protein localisation to nucleus", "upregulation of protein localization in cell nucleus", "upregulation of protein localization in nucleus", "upregulation of protein localization to nucleus" ; oboInOwl:hasNarrowSynonym "activation of protein localisation to nucleus", "activation of protein localization in cell nucleus", "activation of protein localization to nucleus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900182" ; a owl:Class ; rdfs:label "positive regulation of protein localization to nucleus" ; rdfs:subClassOf obo:GO_1900180, obo:GO_1903829, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034504 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034504 ] ) ] . obo:GO_1900193 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of oocyte maturation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-03-19T09:41:18Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900193" ; a owl:Class ; rdfs:label "regulation of oocyte maturation" ; rdfs:subClassOf obo:GO_1903429, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001556 ] ) ] . obo:GO_1900194 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-03-19T09:41:27Z" ; oboInOwl:hasExactSynonym "down regulation of oocyte maturation", "down-regulation of oocyte maturation", "downregulation of oocyte maturation" ; oboInOwl:hasNarrowSynonym "inhibition of oocyte maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900194" ; a owl:Class ; rdfs:label "negative regulation of oocyte maturation" ; rdfs:subClassOf obo:GO_1900193, obo:GO_1903430, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001556 ] ) ] . obo:GO_1900195 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of oocyte maturation." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-03-19T09:41:35Z" ; oboInOwl:hasExactSynonym "up regulation of oocyte maturation", "up-regulation of oocyte maturation", "upregulation of oocyte maturation" ; oboInOwl:hasNarrowSynonym "activation of oocyte maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900195" ; a owl:Class ; rdfs:label "positive regulation of oocyte maturation" ; rdfs:subClassOf obo:GO_1900193, obo:GO_1903431, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001556 ] ) ] . obo:GO_1900242 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2012-03-28T01:40:26Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of synaptic vesicle retrieval" ; oboInOwl:id "GO:1900242" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of synaptic vesicle endocytosis" ; rdfs:subClassOf obo:GO_0030100, obo:GO_1903421, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048488 ] ) ] . obo:GO_1900243 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2012-03-28T01:40:36Z" ; oboInOwl:hasExactSynonym "down regulation of synaptic vesicle endocytosis", "down-regulation of synaptic vesicle endocytosis", "downregulation of synaptic vesicle endocytosis" ; oboInOwl:hasNarrowSynonym "inhibition of synaptic vesicle endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of synaptic vesicle retrieval", "down-regulation of synaptic vesicle retrieval", "downregulation of synaptic vesicle retrieval", "inhibition of synaptic vesicle retrieval", "negative regulation of synaptic vesicle retrieval" ; oboInOwl:id "GO:1900243" ; a owl:Class ; rdfs:label "negative regulation of synaptic vesicle endocytosis" ; rdfs:subClassOf obo:GO_0045806, obo:GO_1900242, obo:GO_1903422, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048488 ] ) ] . obo:GO_1900244 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2012-03-28T01:40:44Z" ; oboInOwl:hasExactSynonym "up regulation of synaptic vesicle endocytosis", "up-regulation of synaptic vesicle endocytosis", "upregulation of synaptic vesicle endocytosis" ; oboInOwl:hasNarrowSynonym "activation of synaptic vesicle endocytosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of synaptic vesicle retrieval", "positive regulation of synaptic vesicle retrieval", "up regulation of synaptic vesicle retrieval", "up-regulation of synaptic vesicle retrieval", "upregulation of synaptic vesicle retrieval" ; oboInOwl:id "GO:1900244" ; a owl:Class ; rdfs:label "positive regulation of synaptic vesicle endocytosis" ; rdfs:subClassOf obo:GO_0045807, obo:GO_1900242, obo:GO_1903423, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048488 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048488 ] ) ] . obo:GO_1900407 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cellular response to oxidative stress." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-04-20T03:30:52Z" ; oboInOwl:hasNarrowSynonym "regulation of adaptive response to oxidative stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900407" ; a owl:Class ; rdfs:label "regulation of cellular response to oxidative stress" ; rdfs:subClassOf obo:GO_0080135, obo:GO_1902882, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034599 ] ) ] . obo:GO_1900408 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-04-20T03:31:05Z" ; oboInOwl:hasExactSynonym "down regulation of cellular response to oxidative stress", "down-regulation of cellular response to oxidative stress", "downregulation of cellular response to oxidative stress" ; oboInOwl:hasNarrowSynonym "down regulation of adaptive response to oxidative stress", "down-regulation of adaptive response to oxidative stress", "downregulation of adaptive response to oxidative stress", "inhibition of adaptive response to oxidative stress", "inhibition of cellular response to oxidative stress", "negative regulation of adaptive response to oxidative stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900408" ; a owl:Class ; rdfs:label "negative regulation of cellular response to oxidative stress" ; rdfs:subClassOf obo:GO_0048523, obo:GO_1900407, obo:GO_1902883, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034599 ] ) ] . obo:GO_1900409 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-04-20T03:31:16Z" ; oboInOwl:hasExactSynonym "up regulation of cellular response to oxidative stress", "up-regulation of cellular response to oxidative stress", "upregulation of cellular response to oxidative stress" ; oboInOwl:hasNarrowSynonym "activation of adaptive response to oxidative stress", "activation of cellular response to oxidative stress", "positive regulation of adaptive response to oxidative stress", "up regulation of adaptive response to oxidative stress", "up-regulation of adaptive response to oxidative stress", "upregulation of adaptive response to oxidative stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900409" ; a owl:Class ; rdfs:label "positive regulation of cellular response to oxidative stress" ; rdfs:subClassOf obo:GO_0048522, obo:GO_1900407, obo:GO_1902884, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034599 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034599 ] ) ] . obo:GO_1900619 obo:IAO_0000115 "The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-05-16T12:29:51Z" ; oboInOwl:hasExactSynonym "acetate ester metabolism", "acetyl ester metabolic process", "acetyl ester metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1900619" ; a owl:Class ; rdfs:label "acetate ester metabolic process" ; rdfs:subClassOf obo:GO_0071704 . obo:GO_1901031 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of response to reactive oxygen species." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-06-20T07:47:06Z" ; oboInOwl:hasExactSynonym "regulation of response to AOS", "regulation of response to ROI", "regulation of response to ROS", "regulation of response to active oxygen species", "regulation of response to reactive oxidative species", "regulation of response to reactive oxygen intermediate" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901031" ; a owl:Class ; rdfs:label "regulation of response to reactive oxygen species" ; rdfs:subClassOf obo:GO_1902882, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000302 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000302 ] ) ] . obo:GO_1901032 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-06-20T07:47:28Z" ; oboInOwl:hasExactSynonym "down regulation of response to AOS", "down regulation of response to ROI", "down regulation of response to ROS", "down regulation of response to active oxygen species", "down regulation of response to reactive oxidative species", "down regulation of response to reactive oxygen intermediate", "down regulation of response to reactive oxygen species", "down-regulation of response to AOS", "down-regulation of response to ROI", "down-regulation of response to ROS", "down-regulation of response to active oxygen species", "down-regulation of response to reactive oxidative species", "down-regulation of response to reactive oxygen intermediate", "down-regulation of response to reactive oxygen species", "downregulation of response to AOS", "downregulation of response to ROI", "downregulation of response to ROS", "downregulation of response to active oxygen species", "downregulation of response to reactive oxidative species", "downregulation of response to reactive oxygen intermediate", "downregulation of response to reactive oxygen species", "inhibition of response to AOS", "inhibition of response to ROI", "inhibition of response to ROS", "inhibition of response to active oxygen species", "inhibition of response to reactive oxidative species", "inhibition of response to reactive oxygen intermediate", "negative regulation of response to AOS", "negative regulation of response to ROI", "negative regulation of response to ROS", "negative regulation of response to active oxygen species", "negative regulation of response to reactive oxidative species", "negative regulation of response to reactive oxygen intermediate" ; oboInOwl:hasNarrowSynonym "inhibition of response to reactive oxygen species" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901032" ; a owl:Class ; rdfs:label "negative regulation of response to reactive oxygen species" ; rdfs:subClassOf obo:GO_1901031, obo:GO_1902883, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000302 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000302 ] ) ] . obo:GO_1901033 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-06-20T07:47:35Z" ; oboInOwl:hasExactSynonym "activation of response to AOS", "activation of response to ROI", "activation of response to ROS", "activation of response to active oxygen species", "activation of response to reactive oxidative species", "activation of response to reactive oxygen intermediate", "positive regulation of response to AOS", "positive regulation of response to ROI", "positive regulation of response to ROS", "positive regulation of response to active oxygen species", "positive regulation of response to reactive oxidative species", "positive regulation of response to reactive oxygen intermediate", "up regulation of response to AOS", "up regulation of response to ROI", "up regulation of response to ROS", "up regulation of response to active oxygen species", "up regulation of response to reactive oxidative species", "up regulation of response to reactive oxygen intermediate", "up regulation of response to reactive oxygen species", "up-regulation of response to AOS", "up-regulation of response to ROI", "up-regulation of response to ROS", "up-regulation of response to active oxygen species", "up-regulation of response to reactive oxidative species", "up-regulation of response to reactive oxygen intermediate", "up-regulation of response to reactive oxygen species", "upregulation of response to AOS", "upregulation of response to ROI", "upregulation of response to ROS", "upregulation of response to active oxygen species", "upregulation of response to reactive oxidative species", "upregulation of response to reactive oxygen intermediate", "upregulation of response to reactive oxygen species" ; oboInOwl:hasNarrowSynonym "activation of response to reactive oxygen species" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901033" ; a owl:Class ; rdfs:label "positive regulation of response to reactive oxygen species" ; rdfs:subClassOf obo:GO_1901031, obo:GO_1902884, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000302 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000302 ] ) ] . obo:GO_1901045 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of oviposition." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-06-27T06:19:58Z" ; oboInOwl:hasBroadSynonym "down regulation of egg laying", "down regulation of egg-laying", "down-regulation of egg laying", "down-regulation of egg-laying", "downregulation of egg laying", "downregulation of egg-laying", "inhibition of egg laying", "inhibition of egg-laying", "negative regulation of egg laying", "negative regulation of egg-laying" ; oboInOwl:hasExactSynonym "down regulation of oviposition", "down-regulation of oviposition", "downregulation of oviposition", "negative regulation of oviposition" ; oboInOwl:hasNarrowSynonym "inhibition of oviposition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901045" ; a owl:Class ; rdfs:label "negative regulation of egg-laying behavior" ; rdfs:subClassOf obo:GO_0046662, obo:GO_0048521, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0018991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0018991 ] ) ] . obo:GO_1901046 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of oviposition." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-06-27T06:20:20Z" ; oboInOwl:hasBroadSynonym "activation of egg laying", "activation of egg-laying", "positive regulation of egg laying", "positive regulation of egg-laying", "up regulation of egg laying", "up regulation of egg-laying", "up-regulation of egg laying", "up-regulation of egg-laying", "upregulation of egg laying", "upregulation of egg-laying" ; oboInOwl:hasExactSynonym "positive regulation of oviposition", "up regulation of oviposition", "up-regulation of oviposition", "upregulation of oviposition" ; oboInOwl:hasNarrowSynonym "activation of oviposition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901046" ; a owl:Class ; rdfs:label "positive regulation of egg-laying behavior" ; rdfs:subClassOf obo:GO_0046662, obo:GO_0048520, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0018991 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0018991 ] ) ] . obo:GO_1901074 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-07-02T07:32:21Z" ; oboInOwl:hasExactSynonym "regulation of engulfment of apoptotic cell corpse", "regulation of engulfment of cell corpse" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901074" ; a owl:Class ; rdfs:label "regulation of engulfment of apoptotic cell" ; rdfs:subClassOf obo:GO_0060099, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043652 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043652 ] ) ] . obo:GO_1901075 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-07-02T07:32:43Z" ; oboInOwl:hasExactSynonym "down regulation of engulfment of apoptotic cell", "down regulation of engulfment of apoptotic cell corpse", "down regulation of engulfment of cell corpse", "down-regulation of engulfment of apoptotic cell", "down-regulation of engulfment of apoptotic cell corpse", "down-regulation of engulfment of cell corpse", "downregulation of engulfment of apoptotic cell", "downregulation of engulfment of apoptotic cell corpse", "downregulation of engulfment of cell corpse", "negative regulation of engulfment of apoptotic cell corpse", "negative regulation of engulfment of cell corpse" ; oboInOwl:hasNarrowSynonym "inhibition of engulfment of apoptotic cell", "inhibition of engulfment of apoptotic cell corpse", "inhibition of engulfment of cell corpse" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901075" ; a owl:Class ; rdfs:label "negative regulation of engulfment of apoptotic cell" ; rdfs:subClassOf obo:GO_0060101, obo:GO_1901074, obo:GO_2000426, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043652 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043652 ] ) ] . obo:GO_1901076 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2012-07-02T07:32:51Z" ; oboInOwl:hasExactSynonym "positive regulation of engulfment of apoptotic cell corpse", "positive regulation of engulfment of cell corpse", "up regulation of engulfment of apoptotic cell", "up regulation of engulfment of apoptotic cell corpse", "up regulation of engulfment of cell corpse", "up-regulation of engulfment of apoptotic cell", "up-regulation of engulfment of apoptotic cell corpse", "up-regulation of engulfment of cell corpse", "upregulation of engulfment of apoptotic cell", "upregulation of engulfment of apoptotic cell corpse", "upregulation of engulfment of cell corpse" ; oboInOwl:hasNarrowSynonym "activation of engulfment of apoptotic cell", "activation of engulfment of apoptotic cell corpse", "activation of engulfment of cell corpse" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901076" ; a owl:Class ; rdfs:label "positive regulation of engulfment of apoptotic cell" ; rdfs:subClassOf obo:GO_0060100, obo:GO_1901074, obo:GO_2000427, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043652 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043652 ] ) ] . obo:GO_1901160 obo:IAO_0000115 "The chemical reactions and pathways involving primary amino compound." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-07-18T04:44:39Z" ; oboInOwl:hasExactSynonym "primary amino compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901160" ; a owl:Class ; rdfs:label "primary amino compound metabolic process" ; rdfs:subClassOf obo:GO_1901564 . obo:GO_1901161 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of primary amino compound." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-07-18T04:45:06Z" ; oboInOwl:hasExactSynonym "primary amino compound breakdown", "primary amino compound catabolism", "primary amino compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901161" ; a owl:Class ; rdfs:label "primary amino compound catabolic process" ; rdfs:subClassOf obo:GO_1901160, obo:GO_1901565 . obo:GO_1901162 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of primary amino compound." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-07-18T04:45:14Z" ; oboInOwl:hasExactSynonym "primary amino compound anabolism", "primary amino compound biosynthesis", "primary amino compound formation", "primary amino compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901162" ; a owl:Class ; rdfs:label "primary amino compound biosynthetic process" ; rdfs:subClassOf obo:GO_1901160, obo:GO_1901566 . obo:GO_1901360 obo:IAO_0000115 "The chemical reactions and pathways involving organic cyclic compound." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-09-14T09:03:51Z" ; oboInOwl:hasExactSynonym "organic cyclic compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901360" ; a owl:Class ; rdfs:label "organic cyclic compound metabolic process" ; rdfs:subClassOf obo:GO_0071704 . obo:GO_1901361 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of organic cyclic compound." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-09-14T09:05:04Z" ; oboInOwl:hasExactSynonym "organic cyclic compound breakdown", "organic cyclic compound catabolism", "organic cyclic compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901361" ; a owl:Class ; rdfs:label "organic cyclic compound catabolic process" ; rdfs:subClassOf obo:GO_1901360, obo:GO_1901575 . obo:GO_1901362 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of organic cyclic compound." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2012-09-14T09:05:22Z" ; oboInOwl:hasExactSynonym "organic cyclic compound anabolism", "organic cyclic compound biosynthesis", "organic cyclic compound formation", "organic cyclic compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901362" ; a owl:Class ; rdfs:label "organic cyclic compound biosynthetic process" ; rdfs:subClassOf obo:GO_1901360, obo:GO_1901576 . obo:GO_1901524 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of macromitophagy." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2012-10-22T16:56:45Z" ; oboInOwl:hasExactSynonym "regulation of macromitophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901524" ; a owl:Class ; rdfs:label "regulation of mitophagy" ; rdfs:subClassOf obo:GO_0016241, obo:GO_1903146, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000423 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000423 ] ) ] . obo:GO_1901525 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2012-10-22T16:56:49Z" ; oboInOwl:hasExactSynonym "down regulation of macromitophagy", "down-regulation of macromitophagy", "downregulation of macromitophagy", "negative regulation of macromitophagy" ; oboInOwl:hasNarrowSynonym "inhibition of macromitophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901525" ; a owl:Class ; rdfs:label "negative regulation of mitophagy" ; rdfs:subClassOf obo:GO_0016242, obo:GO_1901524, obo:GO_1903147, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000423 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000423 ] ) ] . obo:GO_1901526 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitophagy." ; oboInOwl:created_by "krc" ; oboInOwl:creation_date "2012-10-22T16:56:57Z" ; oboInOwl:hasExactSynonym "positive regulation of macromitophagy", "up regulation of macromitophagy", "up-regulation of macromitophagy", "upregulation of macromitophagy" ; oboInOwl:hasNarrowSynonym "activation of macromitophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901526" ; a owl:Class ; rdfs:label "positive regulation of mitophagy" ; rdfs:subClassOf obo:GO_0016239, obo:GO_1901524, obo:GO_1903599, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000423 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000423 ] ) ] . obo:GO_1901530 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-10-24T07:12:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901530" ; a owl:Class ; rdfs:label "response to hypochlorite" ; rdfs:subClassOf obo:GO_0000302, obo:GO_0010035, obo:GO_1902074 . obo:GO_1901561 obo:IAO_0000115 "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/21394"^^xsd:anyURI ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-11-02T15:32:33Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901561" ; a owl:Class ; rdfs:comment "This term is out of scope for GO." ; rdfs:label "obsolete response to benomyl" ; owl:deprecated true . obo:GO_1901562 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2012-11-02T15:32:41Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901562" ; a owl:Class ; rdfs:label "response to paraquat" ; rdfs:subClassOf obo:GO_0010033, obo:GO_1902074 . obo:GO_1901564 obo:IAO_0000115 "The chemical reactions and pathways involving organonitrogen compound." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-04T15:17:52Z" ; oboInOwl:hasExactSynonym "organonitrogen compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901564" ; a owl:Class ; rdfs:label "organonitrogen compound metabolic process" ; rdfs:subClassOf obo:GO_0006807, obo:GO_0071704 . obo:GO_1901565 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of organonitrogen compound." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-04T15:17:56Z" ; oboInOwl:hasExactSynonym "organonitrogen compound breakdown", "organonitrogen compound catabolism", "organonitrogen compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901565" ; a owl:Class ; rdfs:label "organonitrogen compound catabolic process" ; rdfs:subClassOf obo:GO_1901564, obo:GO_1901575 . obo:GO_1901566 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of organonitrogen compound." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-04T15:18:00Z" ; oboInOwl:hasExactSynonym "organonitrogen compound anabolism", "organonitrogen compound biosynthesis", "organonitrogen compound formation", "organonitrogen compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901566" ; a owl:Class ; rdfs:label "organonitrogen compound biosynthetic process" ; rdfs:subClassOf obo:GO_1901564, obo:GO_1901576 . obo:GO_1901575 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-05T11:04:36Z" ; oboInOwl:hasExactSynonym "organic molecular entity breakdown", "organic molecular entity catabolic process", "organic molecular entity catabolism", "organic molecular entity degradation", "organic substance breakdown", "organic substance catabolism", "organic substance degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901575" ; a owl:Class ; rdfs:label "organic substance catabolic process" ; rdfs:subClassOf obo:GO_0009056, obo:GO_0071704 . obo:GO_1901576 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-05T11:04:40Z" ; oboInOwl:hasExactSynonym "organic molecular entity anabolism", "organic molecular entity biosynthesis", "organic molecular entity biosynthetic process", "organic molecular entity formation", "organic molecular entity synthesis", "organic substance anabolism", "organic substance biosynthesis", "organic substance formation", "organic substance synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901576" ; a owl:Class ; rdfs:label "organic substance biosynthetic process" ; rdfs:subClassOf obo:GO_0009058, obo:GO_0071704 . obo:GO_1901588 obo:IAO_0000115 "Any microtubule in a dendrite, a neuron projection." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-07T14:37:30Z" ; oboInOwl:hasDbXref "NIF_Subcellular:sao110773650" ; oboInOwl:hasExactSynonym "microtubule of dendrite", "microtubulus of dendrite" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:1901588" ; a owl:Class ; rdfs:label "dendritic microtubule" ; rdfs:subClassOf obo:GO_0005874, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030425 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005874 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030425 ] ) ] . obo:GO_1901608 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2012-11-08T21:49:44Z" ; oboInOwl:hasExactSynonym "regulation of microtubule-based vesicle localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901608" ; a owl:Class ; rdfs:label "regulation of vesicle transport along microtubule" ; rdfs:subClassOf obo:GO_1902513, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0047496 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0047496 ] ) ] . obo:GO_1901609 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2012-11-08T21:49:48Z" ; oboInOwl:hasExactSynonym "down regulation of microtubule-based vesicle localization", "down regulation of vesicle transport along microtubule", "down-regulation of microtubule-based vesicle localization", "down-regulation of vesicle transport along microtubule", "downregulation of microtubule-based vesicle localization", "downregulation of vesicle transport along microtubule", "inhibition of microtubule-based vesicle localization", "negative regulation of microtubule-based vesicle localization" ; oboInOwl:hasNarrowSynonym "inhibition of vesicle transport along microtubule" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901609" ; a owl:Class ; rdfs:label "negative regulation of vesicle transport along microtubule" ; rdfs:subClassOf obo:GO_0032387, obo:GO_1901608, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0047496 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0047496 ] ) ] . obo:GO_1901610 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2012-11-08T21:49:53Z" ; oboInOwl:hasExactSynonym "activation of microtubule-based vesicle localization", "positive regulation of microtubule-based vesicle localization", "up regulation of microtubule-based vesicle localization", "up regulation of vesicle transport along microtubule", "up-regulation of microtubule-based vesicle localization", "up-regulation of vesicle transport along microtubule", "upregulation of microtubule-based vesicle localization", "upregulation of vesicle transport along microtubule" ; oboInOwl:hasNarrowSynonym "activation of vesicle transport along microtubule" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901610" ; a owl:Class ; rdfs:label "positive regulation of vesicle transport along microtubule" ; rdfs:subClassOf obo:GO_0032388, obo:GO_1901608, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0047496 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0047496 ] ) ] . obo:GO_1901615 obo:IAO_0000115 "The chemical reactions and pathways involving organic hydroxy compound." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-13T12:54:27Z" ; oboInOwl:hasExactSynonym "organic hydroxy compound metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901615" ; a owl:Class ; rdfs:label "organic hydroxy compound metabolic process" ; rdfs:subClassOf obo:GO_0071704 . obo:GO_1901616 obo:IAO_0000115 "The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-13T12:54:31Z" ; oboInOwl:hasExactSynonym "organic hydroxy compound breakdown", "organic hydroxy compound catabolism", "organic hydroxy compound degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901616" ; a owl:Class ; rdfs:label "organic hydroxy compound catabolic process" ; rdfs:subClassOf obo:GO_1901575, obo:GO_1901615 . obo:GO_1901617 obo:IAO_0000115 "The chemical reactions and pathways resulting in the formation of organic hydroxy compound." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-11-13T12:54:36Z" ; oboInOwl:hasExactSynonym "organic hydroxy compound anabolism", "organic hydroxy compound biosynthesis", "organic hydroxy compound formation", "organic hydroxy compound synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901617" ; a owl:Class ; rdfs:label "organic hydroxy compound biosynthetic process" ; rdfs:subClassOf obo:GO_1901576, obo:GO_1901615 . obo:GO_1901673 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic spindle assembly." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2012-11-22T09:50:00Z" ; oboInOwl:hasExactSynonym "regulation of spindle assembly involved in mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901673" ; a owl:Class ; rdfs:label "regulation of mitotic spindle assembly" ; rdfs:subClassOf obo:GO_0060236, obo:GO_0090169, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0090307 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0090307 ] ) ] . obo:GO_1901698 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-12-13T15:06:08Z" ; oboInOwl:hasExactSynonym "response to nitrogen molecular entity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901698" ; a owl:Class ; rdfs:label "response to nitrogen compound" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_1901700 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2012-12-13T15:11:37Z" ; oboInOwl:hasExactSynonym "response to oxygen molecular entity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901700" ; a owl:Class ; rdfs:label "response to oxygen-containing compound" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_1901858 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2013-02-01T10:05:04Z" ; oboInOwl:hasExactSynonym "regulation of mitochondrial DNA metabolism", "regulation of mtDNA metabolic process", "regulation of mtDNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901858" ; a owl:Class ; rdfs:label "regulation of mitochondrial DNA metabolic process" ; rdfs:subClassOf obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032042 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032042 ] ) ] . obo:GO_1901859 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2013-02-01T10:05:09Z" ; oboInOwl:hasExactSynonym "down regulation of mitochondrial DNA metabolic process", "down regulation of mitochondrial DNA metabolism", "down regulation of mtDNA metabolic process", "down regulation of mtDNA metabolism", "down-regulation of mitochondrial DNA metabolic process", "down-regulation of mitochondrial DNA metabolism", "down-regulation of mtDNA metabolic process", "down-regulation of mtDNA metabolism", "downregulation of mitochondrial DNA metabolic process", "downregulation of mitochondrial DNA metabolism", "downregulation of mtDNA metabolic process", "downregulation of mtDNA metabolism", "inhibition of mitochondrial DNA metabolism", "inhibition of mtDNA metabolic process", "inhibition of mtDNA metabolism", "negative regulation of mitochondrial DNA metabolism", "negative regulation of mtDNA metabolic process", "negative regulation of mtDNA metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of mitochondrial DNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901859" ; a owl:Class ; rdfs:label "negative regulation of mitochondrial DNA metabolic process" ; rdfs:subClassOf obo:GO_0051053, obo:GO_1901858, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032042 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032042 ] ) ] . obo:GO_1901860 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2013-02-01T10:05:14Z" ; oboInOwl:hasExactSynonym "activation of mitochondrial DNA metabolism", "activation of mtDNA metabolic process", "activation of mtDNA metabolism", "positive regulation of mitochondrial DNA metabolism", "positive regulation of mtDNA metabolic process", "positive regulation of mtDNA metabolism", "up regulation of mitochondrial DNA metabolic process", "up regulation of mitochondrial DNA metabolism", "up regulation of mtDNA metabolic process", "up regulation of mtDNA metabolism", "up-regulation of mitochondrial DNA metabolic process", "up-regulation of mitochondrial DNA metabolism", "up-regulation of mtDNA metabolic process", "up-regulation of mtDNA metabolism", "upregulation of mitochondrial DNA metabolic process", "upregulation of mitochondrial DNA metabolism", "upregulation of mtDNA metabolic process", "upregulation of mtDNA metabolism" ; oboInOwl:hasNarrowSynonym "activation of mitochondrial DNA metabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901860" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial DNA metabolic process" ; rdfs:subClassOf obo:GO_0010822, obo:GO_0051054, obo:GO_1901858, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032042 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032042 ] ) ] . obo:GO_1901879 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein depolymerization." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2013-02-06T13:57:23Z" ; oboInOwl:hasExactSynonym "regulation of protein polymer breakdown", "regulation of protein polymer catabolic process", "regulation of protein polymer catabolism", "regulation of protein polymer degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901879" ; a owl:Class ; rdfs:label "regulation of protein depolymerization" ; rdfs:subClassOf obo:GO_0043244, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051261 ] ) ] . obo:GO_1901880 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2013-02-06T13:57:28Z" ; oboInOwl:hasExactSynonym "down regulation of protein depolymerization", "down regulation of protein polymer breakdown", "down regulation of protein polymer catabolic process", "down regulation of protein polymer catabolism", "down regulation of protein polymer degradation", "down-regulation of protein depolymerization", "down-regulation of protein polymer breakdown", "down-regulation of protein polymer catabolic process", "down-regulation of protein polymer catabolism", "down-regulation of protein polymer degradation", "downregulation of protein depolymerization", "downregulation of protein polymer breakdown", "downregulation of protein polymer catabolic process", "downregulation of protein polymer catabolism", "downregulation of protein polymer degradation", "inhibition of protein polymer breakdown", "inhibition of protein polymer catabolic process", "inhibition of protein polymer catabolism", "inhibition of protein polymer degradation", "negative regulation of protein polymer breakdown", "negative regulation of protein polymer catabolic process", "negative regulation of protein polymer catabolism", "negative regulation of protein polymer degradation" ; oboInOwl:hasNarrowSynonym "inhibition of protein depolymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901880" ; a owl:Class ; rdfs:label "negative regulation of protein depolymerization" ; rdfs:subClassOf obo:GO_0043242, obo:GO_1901879, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051261 ] ) ] . obo:GO_1901881 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein depolymerization." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2013-02-06T13:57:32Z" ; oboInOwl:hasExactSynonym "activation of protein polymer breakdown", "activation of protein polymer catabolic process", "activation of protein polymer catabolism", "activation of protein polymer degradation", "positive regulation of protein polymer breakdown", "positive regulation of protein polymer catabolic process", "positive regulation of protein polymer catabolism", "positive regulation of protein polymer degradation", "up regulation of protein depolymerization", "up regulation of protein polymer breakdown", "up regulation of protein polymer catabolic process", "up regulation of protein polymer catabolism", "up regulation of protein polymer degradation", "up-regulation of protein depolymerization", "up-regulation of protein polymer breakdown", "up-regulation of protein polymer catabolic process", "up-regulation of protein polymer catabolism", "up-regulation of protein polymer degradation", "upregulation of protein depolymerization", "upregulation of protein polymer breakdown", "upregulation of protein polymer catabolic process", "upregulation of protein polymer catabolism", "upregulation of protein polymer degradation" ; oboInOwl:hasNarrowSynonym "activation of protein depolymerization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901881" ; a owl:Class ; rdfs:label "positive regulation of protein depolymerization" ; rdfs:subClassOf obo:GO_0043243, obo:GO_1901879, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051261 ] ) ] . obo:GO_1901888 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell junction assembly." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2013-02-06T19:40:32Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901888" ; a owl:Class ; rdfs:label "regulation of cell junction assembly" ; rdfs:subClassOf obo:GO_0044087, obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034329 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034329 ] ) ] . obo:GO_1901889 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2013-02-06T19:40:41Z" ; oboInOwl:hasExactSynonym "down regulation of cell junction assembly", "down-regulation of cell junction assembly", "downregulation of cell junction assembly" ; oboInOwl:hasNarrowSynonym "inhibition of cell junction assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901889" ; a owl:Class ; rdfs:label "negative regulation of cell junction assembly" ; rdfs:subClassOf obo:GO_0051129, obo:GO_1901888, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034329 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034329 ] ) ] . obo:GO_1901890 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell junction assembly." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2013-02-06T19:40:46Z" ; oboInOwl:hasExactSynonym "up regulation of cell junction assembly", "up-regulation of cell junction assembly", "upregulation of cell junction assembly" ; oboInOwl:hasNarrowSynonym "activation of cell junction assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901890" ; a owl:Class ; rdfs:label "positive regulation of cell junction assembly" ; rdfs:subClassOf obo:GO_0044089, obo:GO_0051130, obo:GO_1901888, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034329 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034329 ] ) ] . obo:GO_1901970 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2013-02-22T19:06:19Z" ; oboInOwl:hasExactSynonym "activation of mitotic sister chromatid resolution", "activation of sister chromatid separation during mitosis", "positive regulation of mitotic sister chromatid resolution", "positive regulation of sister chromatid separation during mitosis", "up regulation of mitotic sister chromatid resolution", "up regulation of mitotic sister chromatid separation", "up regulation of sister chromatid separation during mitosis", "up-regulation of mitotic sister chromatid resolution", "up-regulation of mitotic sister chromatid separation", "up-regulation of sister chromatid separation during mitosis", "upregulation of mitotic sister chromatid resolution", "upregulation of mitotic sister chromatid separation", "upregulation of sister chromatid separation during mitosis" ; oboInOwl:hasNarrowSynonym "activation of mitotic sister chromatid separation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of chromosome separation during mitosis", "activation of mitotic chromosome separation", "positive regulation of chromosome separation during mitosis", "positive regulation of mitotic chromosome separation", "up regulation of chromosome separation during mitosis", "up regulation of mitotic chromosome separation", "up-regulation of chromosome separation during mitosis", "up-regulation of mitotic chromosome separation", "upregulation of chromosome separation during mitosis", "upregulation of mitotic chromosome separation" ; oboInOwl:id "GO:1901970" ; a owl:Class ; rdfs:label "positive regulation of mitotic sister chromatid separation" ; rdfs:subClassOf obo:GO_0010965, obo:GO_1905820, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051306 ] ) ] . obo:GO_1901976 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell cycle checkpoint." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-06T15:10:20Z" ; oboInOwl:hasAlternativeId "GO:2001047" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of G1/S checkpoint", "regulation of G1/S transition checkpoint" ; oboInOwl:id "GO:1901976" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc)." ; rdfs:label "regulation of cell cycle checkpoint" ; rdfs:subClassOf obo:GO_1901987, obo:GO_1902531, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000075 ] ) ] . obo:GO_1901977 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-06T15:10:29Z" ; oboInOwl:hasAlternativeId "GO:2001048" ; oboInOwl:hasExactSynonym "down regulation of cell cycle checkpoint", "down-regulation of cell cycle checkpoint", "downregulation of cell cycle checkpoint" ; oboInOwl:hasNarrowSynonym "inhibition of cell cycle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of G1/S checkpoint", "negative regulation of G1/S transition checkpoint" ; oboInOwl:id "GO:1901977" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of checkpoint (i.e mitotic spindle or DNA damage etc)." ; rdfs:label "negative regulation of cell cycle checkpoint" ; rdfs:subClassOf obo:GO_1901976, obo:GO_1901989, obo:GO_1902532, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000075 ] ) ] . obo:GO_1901978 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-06T15:10:34Z" ; oboInOwl:hasAlternativeId "GO:2001052" ; oboInOwl:hasExactSynonym "up regulation of cell cycle checkpoint", "up-regulation of cell cycle checkpoint", "upregulation of cell cycle checkpoint" ; oboInOwl:hasNarrowSynonym "activation of cell cycle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of G1/S checkpoint", "positive regulation of G1/S transition checkpoint" ; oboInOwl:id "GO:1901978" ; a owl:Class ; rdfs:label "positive regulation of cell cycle checkpoint" ; rdfs:subClassOf obo:GO_1901976, obo:GO_1902533, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000075 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000075 ] ) ] . obo:GO_1901987 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell cycle phase transition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-19T16:11:27Z" ; oboInOwl:hasExactSynonym "cell cycle control", "regulation of cell cycle transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901987" ; a owl:Class ; rdfs:label "regulation of cell cycle phase transition" ; rdfs:subClassOf obo:GO_0010564, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044770 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044770 ] ) ] . obo:GO_1901988 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-19T16:11:32Z" ; oboInOwl:hasExactSynonym "down regulation of cell cycle phase transition", "down regulation of cell cycle transition", "down-regulation of cell cycle phase transition", "down-regulation of cell cycle transition", "downregulation of cell cycle phase transition", "downregulation of cell cycle transition", "inhibition of cell cycle transition", "negative regulation of cell cycle transition" ; oboInOwl:hasNarrowSynonym "inhibition of cell cycle phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901988" ; a owl:Class ; rdfs:label "negative regulation of cell cycle phase transition" ; rdfs:subClassOf obo:GO_0010948, obo:GO_1901987, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044770 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044770 ] ) ] . obo:GO_1901989 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell cycle phase transition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-19T16:11:37Z" ; oboInOwl:hasExactSynonym "activation of cell cycle transition", "positive regulation of cell cycle transition", "up regulation of cell cycle phase transition", "up regulation of cell cycle transition", "up-regulation of cell cycle phase transition", "up-regulation of cell cycle transition", "upregulation of cell cycle phase transition", "upregulation of cell cycle transition" ; oboInOwl:hasNarrowSynonym "activation of cell cycle phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901989" ; a owl:Class ; rdfs:label "positive regulation of cell cycle phase transition" ; rdfs:subClassOf obo:GO_0090068, obo:GO_1901987, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044770 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044770 ] ) ] . obo:GO_1901990 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-19T16:14:38Z" ; oboInOwl:hasExactSynonym "mitotic cell cycle control" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901990" ; a owl:Class ; rdfs:label "regulation of mitotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_0007346, obo:GO_1901987, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044772 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044772 ] ) ] . obo:GO_1901991 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-19T16:14:46Z" ; oboInOwl:hasExactSynonym "down regulation of mitotic cell cycle phase transition", "down-regulation of mitotic cell cycle phase transition", "downregulation of mitotic cell cycle phase transition" ; oboInOwl:hasNarrowSynonym "inhibition of mitotic cell cycle phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901991" ; a owl:Class ; rdfs:label "negative regulation of mitotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_0045930, obo:GO_1901988, obo:GO_1901990, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044772 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044772 ] ) ] . obo:GO_1901992 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-19T16:14:51Z" ; oboInOwl:hasExactSynonym "up regulation of mitotic cell cycle phase transition", "up-regulation of mitotic cell cycle phase transition", "upregulation of mitotic cell cycle phase transition" ; oboInOwl:hasNarrowSynonym "activation of mitotic cell cycle phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901992" ; a owl:Class ; rdfs:label "positive regulation of mitotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_0045931, obo:GO_1901989, obo:GO_1901990, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044772 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044772 ] ) ] . obo:GO_1901993 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-19T16:14:58Z" ; oboInOwl:hasBroadSynonym "regulation of cell cycle transition" ; oboInOwl:hasExactSynonym "meiotic cell cycle control" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901993" ; a owl:Class ; rdfs:label "regulation of meiotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_1901987, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044771 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044771 ] ) ] . obo:GO_1901994 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-19T16:15:03Z" ; oboInOwl:hasBroadSynonym "down regulation of cell cycle transition", "down-regulation of cell cycle transition", "downregulation of cell cycle transition", "inhibition of cell cycle transition", "negative regulation of cell cycle transition" ; oboInOwl:hasExactSynonym "down regulation of meiotic cell cycle phase transition", "down-regulation of meiotic cell cycle phase transition", "downregulation of meiotic cell cycle phase transition" ; oboInOwl:hasNarrowSynonym "inhibition of meiotic cell cycle phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901994" ; a owl:Class ; rdfs:label "negative regulation of meiotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_0051447, obo:GO_1901988, obo:GO_1901993, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044771 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044771 ] ) ] . obo:GO_1901995 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-03-19T16:15:08Z" ; oboInOwl:hasBroadSynonym "activation of cell cycle transition", "positive regulation of cell cycle transition", "up regulation of cell cycle transition", "up-regulation of cell cycle transition", "upregulation of cell cycle transition" ; oboInOwl:hasExactSynonym "up regulation of meiotic cell cycle phase transition", "up-regulation of meiotic cell cycle phase transition", "upregulation of meiotic cell cycle phase transition" ; oboInOwl:hasNarrowSynonym "activation of meiotic cell cycle phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1901995" ; a owl:Class ; rdfs:label "positive regulation of meiotic cell cycle phase transition" ; rdfs:subClassOf obo:GO_0051446, obo:GO_1901989, obo:GO_1901993, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044771 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044771 ] ) ] . obo:GO_1902010 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-03-22T13:43:26Z" ; oboInOwl:hasExactSynonym "down regulation of protein biosynthetic process involved in ER stress response", "down regulation of protein biosynthetic process involved in response to ER stress", "down regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress", "down-regulation of protein biosynthetic process involved in ER stress response", "down-regulation of protein biosynthetic process involved in response to ER stress", "down-regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress", "downregulation of protein biosynthetic process involved in ER stress response", "downregulation of protein biosynthetic process involved in response to ER stress", "downregulation of protein biosynthetic process involved in response to endoplasmic reticulum stress", "negative regulation of protein anabolism involved in ER stress response", "negative regulation of protein anabolism involved in response to ER stress", "negative regulation of protein anabolism involved in response to endoplasmic reticulum stress", "negative regulation of protein biosynthesis involved in ER stress response", "negative regulation of protein biosynthesis involved in response to ER stress", "negative regulation of protein biosynthesis involved in response to endoplasmic reticulum stress", "negative regulation of protein biosynthetic process involved in ER stress response", "negative regulation of protein biosynthetic process involved in response to ER stress", "negative regulation of protein biosynthetic process involved in response to endoplasmic reticulum stress", "negative regulation of protein formation involved in ER stress response", "negative regulation of protein formation involved in response to ER stress", "negative regulation of protein formation involved in response to endoplasmic reticulum stress", "negative regulation of protein synthesis involved in ER stress response", "negative regulation of protein synthesis involved in response to ER stress", "negative regulation of protein synthesis involved in response to endoplasmic reticulum stress", "negative regulation of translation involved in ER stress response", "negative regulation of translation involved in response to ER stress" ; oboInOwl:hasNarrowSynonym "inhibition of protein biosynthetic process involved in ER stress response", "inhibition of protein biosynthetic process involved in response to ER stress", "inhibition of protein biosynthetic process involved in response to endoplasmic reticulum stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "protein biosynthesis inhibitor activity involved in ER stress response", "protein biosynthesis inhibitor activity involved in response to ER stress", "protein biosynthesis inhibitor activity involved in response to endoplasmic reticulum stress", "protein biosynthetic process inhibitor activity involved in ER stress response", "protein biosynthetic process inhibitor activity involved in response to ER stress", "protein biosynthetic process inhibitor activity involved in response to endoplasmic reticulum stress" ; oboInOwl:id "GO:1902010" ; a owl:Class ; rdfs:label "negative regulation of translation in response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0032055, obo:GO_0036490 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034976 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006412 ] ) ] . obo:GO_1902074 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus." ; oboInOwl:created_by "mls" ; oboInOwl:creation_date "2013-04-22T15:41:57Z" ; oboInOwl:hasNarrowSynonym "response to salinity" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902074" ; a owl:Class ; rdfs:label "response to salt" ; rdfs:subClassOf obo:GO_0042221 . obo:GO_1902099 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T12:45:15Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902099" ; a owl:Class ; rdfs:label "regulation of metaphase/anaphase transition of cell cycle" ; rdfs:subClassOf obo:GO_0033045, obo:GO_1901987, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044784 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044784 ] ) ] . obo:GO_1902100 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T12:45:20Z" ; oboInOwl:hasExactSynonym "down regulation of metaphase/anaphase transition of cell cycle", "down-regulation of metaphase/anaphase transition of cell cycle", "downregulation of metaphase/anaphase transition of cell cycle" ; oboInOwl:hasNarrowSynonym "inhibition of metaphase/anaphase transition of cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902100" ; a owl:Class ; rdfs:label "negative regulation of metaphase/anaphase transition of cell cycle" ; rdfs:subClassOf obo:GO_1901988, obo:GO_1902099, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044784 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044784 ] ) ] . obo:GO_1902101 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T12:45:30Z" ; oboInOwl:hasExactSynonym "up regulation of metaphase/anaphase transition of cell cycle", "up-regulation of metaphase/anaphase transition of cell cycle", "upregulation of metaphase/anaphase transition of cell cycle" ; oboInOwl:hasNarrowSynonym "activation of metaphase/anaphase transition of cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902101" ; a owl:Class ; rdfs:label "positive regulation of metaphase/anaphase transition of cell cycle" ; rdfs:subClassOf obo:GO_1901989, obo:GO_1902099, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044784 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044784 ] ) ] . obo:GO_1902102 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T12:45:38Z" ; oboInOwl:hasExactSynonym "regulation of meiotic metaphase/anaphase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902102" ; a owl:Class ; rdfs:label "regulation of metaphase/anaphase transition of meiotic cell cycle" ; rdfs:subClassOf obo:GO_1901993, obo:GO_1902099, obo:GO_1905132, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044785 ] ) ] . obo:GO_1902103 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T12:45:43Z" ; oboInOwl:hasExactSynonym "down regulation of meiotic metaphase/anaphase transition", "down regulation of metaphase/anaphase transition of meiotic cell cycle", "down-regulation of meiotic metaphase/anaphase transition", "down-regulation of metaphase/anaphase transition of meiotic cell cycle", "downregulation of meiotic metaphase/anaphase transition", "downregulation of metaphase/anaphase transition of meiotic cell cycle", "inhibition of meiotic metaphase/anaphase transition", "negative regulation of meiotic metaphase/anaphase transition" ; oboInOwl:hasNarrowSynonym "inhibition of metaphase/anaphase transition of meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902103" ; a owl:Class ; rdfs:label "negative regulation of metaphase/anaphase transition of meiotic cell cycle" ; rdfs:subClassOf obo:GO_1901994, obo:GO_1902100, obo:GO_1902102, obo:GO_1905133, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044785 ] ) ] . obo:GO_1902104 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-05-02T12:45:48Z" ; oboInOwl:hasExactSynonym "activation of meiotic metaphase/anaphase transition", "positive regulation of meiotic metaphase/anaphase transition", "up regulation of meiotic metaphase/anaphase transition", "up regulation of metaphase/anaphase transition of meiotic cell cycle", "up-regulation of meiotic metaphase/anaphase transition", "up-regulation of metaphase/anaphase transition of meiotic cell cycle", "upregulation of meiotic metaphase/anaphase transition", "upregulation of metaphase/anaphase transition of meiotic cell cycle" ; oboInOwl:hasNarrowSynonym "activation of metaphase/anaphase transition of meiotic cell cycle" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902104" ; a owl:Class ; rdfs:label "positive regulation of metaphase/anaphase transition of meiotic cell cycle" ; rdfs:subClassOf obo:GO_1901995, obo:GO_1902101, obo:GO_1902102, obo:GO_1905134, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044785 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044785 ] ) ] . obo:GO_1902115 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of organelle assembly." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-05-14T09:43:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902115" ; a owl:Class ; rdfs:label "regulation of organelle assembly" ; rdfs:subClassOf obo:GO_0033043, obo:GO_0044087, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070925 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070925 ] ) ] . obo:GO_1902116 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-05-14T09:43:31Z" ; oboInOwl:hasExactSynonym "down regulation of organelle assembly", "down-regulation of organelle assembly", "downregulation of organelle assembly" ; oboInOwl:hasNarrowSynonym "inhibition of organelle assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902116" ; a owl:Class ; rdfs:label "negative regulation of organelle assembly" ; rdfs:subClassOf obo:GO_0010639, obo:GO_1902115, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070925 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070925 ] ) ] . obo:GO_1902117 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of organelle assembly." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-05-14T09:43:36Z" ; oboInOwl:hasExactSynonym "up regulation of organelle assembly", "up-regulation of organelle assembly", "upregulation of organelle assembly" ; oboInOwl:hasNarrowSynonym "activation of organelle assembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902117" ; a owl:Class ; rdfs:label "positive regulation of organelle assembly" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0044089, obo:GO_1902115, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070925 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070925 ] ) ] . obo:GO_1902119 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of meiotic spindle elongation." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2013-05-15T15:15:48Z" ; oboInOwl:hasExactSynonym "regulation of spindle elongation during meiosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902119" ; a owl:Class ; rdfs:label "regulation of meiotic spindle elongation" ; rdfs:subClassOf obo:GO_0032887, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051232 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051232 ] ) ] . obo:GO_1902120 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2013-05-15T15:15:53Z" ; oboInOwl:hasExactSynonym "down regulation of meiotic spindle elongation", "down regulation of spindle elongation during meiosis", "down-regulation of meiotic spindle elongation", "down-regulation of spindle elongation during meiosis", "downregulation of meiotic spindle elongation", "downregulation of spindle elongation during meiosis", "inhibition of spindle elongation during meiosis", "negative regulation of spindle elongation during meiosis" ; oboInOwl:hasNarrowSynonym "inhibition of meiotic spindle elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902120" ; a owl:Class ; rdfs:label "negative regulation of meiotic spindle elongation" ; rdfs:subClassOf obo:GO_0045835, obo:GO_1902119, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051232 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051232 ] ) ] . obo:GO_1902229 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2013-06-14T09:39:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of DNA damage response, signal transduction resulting in induction of apoptosis" ; oboInOwl:id "GO:1902229" ; a owl:Class ; rdfs:label "regulation of intrinsic apoptotic signaling pathway in response to DNA damage" ; rdfs:subClassOf obo:GO_0080135, obo:GO_2001242, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008630 ] ) ] . obo:GO_1902230 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2013-06-14T09:39:58Z" ; oboInOwl:hasExactSynonym "down regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "down-regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "downregulation of intrinsic apoptotic signaling pathway in response to DNA damage" ; oboInOwl:hasNarrowSynonym "inhibition of intrinsic apoptotic signaling pathway in response to DNA damage" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of DNA damage response, signal transduction resulting in induction of apoptosis", "down-regulation of DNA damage response, signal transduction resulting in induction of apoptosis", "downregulation of DNA damage response, signal transduction resulting in induction of apoptosis", "inhibition of DNA damage response, signal transduction resulting in induction of apoptosis", "negative regulation of DNA damage response, signal transduction resulting in induction of apoptosis" ; oboInOwl:id "GO:1902230" ; a owl:Class ; rdfs:label "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage" ; rdfs:subClassOf obo:GO_1902229, obo:GO_2001243, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008630 ] ) ] . obo:GO_1902231 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2013-06-14T09:40:03Z" ; oboInOwl:hasExactSynonym "up regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "up-regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "upregulation of intrinsic apoptotic signaling pathway in response to DNA damage" ; oboInOwl:hasNarrowSynonym "activation of intrinsic apoptotic signaling pathway in response to DNA damage" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of DNA damage response, signal transduction resulting in induction of apoptosis", "positive regulation of DNA damage response, signal transduction resulting in induction of apoptosis", "up regulation of DNA damage response, signal transduction resulting in induction of apoptosis", "up-regulation of DNA damage response, signal transduction resulting in induction of apoptosis", "upregulation of DNA damage response, signal transduction resulting in induction of apoptosis" ; oboInOwl:id "GO:1902231" ; a owl:Class ; rdfs:label "positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage" ; rdfs:subClassOf obo:GO_1902229, obo:GO_2001244, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008630 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008630 ] ) ] . obo:GO_1902275 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of chromatin organization." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2013-07-01T13:21:52Z" ; oboInOwl:hasAlternativeId "GO:0001672", "GO:1903308" ; oboInOwl:hasExactSynonym "regulation of chromatin organisation", "regulation of establishment or maintenance of chromatin architecture" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of chromatin assembly or disassembly", "regulation of chromatin assembly/disassembly", "regulation of chromatin modification" ; oboInOwl:id "GO:1902275" ; a owl:Class ; rdfs:label "regulation of chromatin organization" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006325 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006325 ] ) ] . obo:GO_1902284 obo:IAO_0000115 "Any neuron projection extension that is involved in neuron projection guidance." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-07-08T15:55:17Z" ; oboInOwl:hasExactSynonym "neuron process extension involved in neuron process guidance", "neuron process extension involved in neuron projection guidance", "neuron process extension involved in neuron protrusion guidance", "neuron process extension involved in neuronal cell projection guidance", "neuron projection extension involved in neuron process guidance", "neuron projection extension involved in neuron protrusion guidance", "neuron projection extension involved in neuronal cell projection guidance", "neuron protrusion extension involved in neuron process guidance", "neuron protrusion extension involved in neuron projection guidance", "neuron protrusion extension involved in neuron protrusion guidance", "neuron protrusion extension involved in neuronal cell projection guidance", "neuronal cell projection extension involved in neuron process guidance", "neuronal cell projection extension involved in neuron projection guidance", "neuronal cell projection extension involved in neuron protrusion guidance", "neuronal cell projection extension involved in neuronal cell projection guidance" ; oboInOwl:hasNarrowSynonym "neurite extension involved in neurite guidance", "neurite extension involved in neuron process guidance", "neurite extension involved in neuron projection guidance", "neurite extension involved in neuron protrusion guidance", "neurite extension involved in neuronal cell projection guidance", "neuron process extension involved in neurite guidance", "neuron projection extension involved in neurite guidance", "neuron protrusion extension involved in neurite guidance", "neuronal cell projection extension involved in neurite guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902284" ; a owl:Class ; rdfs:label "neuron projection extension involved in neuron projection guidance" ; rdfs:subClassOf obo:GO_1990138, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0097485 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_1990138 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0097485 ] ) ] . obo:GO_1902292 obo:IAO_0000115 "Any DNA replication initiation that is involved in cell cycle DNA replication." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-07-09T16:05:54Z" ; oboInOwl:hasExactSynonym "DNA replication initiation involved in cell cycle DNA replication", "DNA-dependent DNA replication initiation involved in cell cycle DNA replication" ; oboInOwl:hasNarrowSynonym "DNA endoreduplication initiation involved in cell cycle DNA replication", "DNA re-replication initiation involved in cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902292" ; a owl:Class ; rdfs:label "cell cycle DNA replication initiation" ; rdfs:subClassOf obo:GO_0006270, obo:GO_0022402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044786 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006270 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0044786 ] ) ] . obo:GO_1902315 obo:IAO_0000115 "Any DNA replication initiation that is involved in nuclear cell cycle DNA replication." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-07-23T14:00:01Z" ; oboInOwl:hasExactSynonym "DNA replication initiation involved in nuclear cell cycle DNA replication" ; oboInOwl:hasNarrowSynonym "DNA endoreduplication initiation involved in nuclear cell cycle DNA replication", "DNA re-replication initiation involved in nuclear cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902315" ; a owl:Class ; rdfs:label "nuclear cell cycle DNA replication initiation" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_1902292, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006270 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0033260 ] ) ] . obo:GO_1902337 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis." ; oboInOwl:created_by "sart" ; oboInOwl:creation_date "2013-07-29T15:03:16Z" ; oboInOwl:hasNarrowSynonym "regulation of apoptosis involved in morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of apoptosis involved in development", "regulation of morphogenetic apoptosis" ; oboInOwl:id "GO:1902337" ; a owl:Class ; rdfs:label "regulation of apoptotic process involved in morphogenesis" ; rdfs:subClassOf obo:GO_1904748, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060561 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060561 ] ) ] . obo:GO_1902338 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis." ; oboInOwl:created_by "sart" ; oboInOwl:creation_date "2013-07-29T15:03:25Z" ; oboInOwl:hasExactSynonym "down regulation of apoptotic process involved in morphogenesis", "down-regulation of apoptotic process involved in morphogenesis", "downregulation of apoptotic process involved in morphogenesis" ; oboInOwl:hasNarrowSynonym "down regulation of apoptosis involved in morphogenesis", "down-regulation of apoptosis involved in morphogenesis", "downregulation of apoptosis involved in morphogenesis", "inhibition of apoptosis involved in morphogenesis", "inhibition of apoptotic process involved in morphogenesis", "negative regulation of apoptosis involved in morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of apoptosis involved in development", "down regulation of morphogenetic apoptosis", "down-regulation of apoptosis involved in development", "down-regulation of morphogenetic apoptosis", "downregulation of apoptosis involved in development", "downregulation of morphogenetic apoptosis", "inhibition of apoptosis involved in development", "inhibition of morphogenetic apoptosis", "negative regulation of apoptosis involved in development", "negative regulation of morphogenetic apoptosis" ; oboInOwl:id "GO:1902338" ; a owl:Class ; rdfs:label "negative regulation of apoptotic process involved in morphogenesis" ; rdfs:subClassOf obo:GO_1902337, obo:GO_1904746, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060561 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060561 ] ) ] . obo:GO_1902339 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis." ; oboInOwl:created_by "sart" ; oboInOwl:creation_date "2013-07-29T15:03:33Z" ; oboInOwl:hasExactSynonym "up regulation of apoptotic process involved in morphogenesis", "up-regulation of apoptotic process involved in morphogenesis", "upregulation of apoptotic process involved in morphogenesis" ; oboInOwl:hasNarrowSynonym "activation of apoptosis involved in morphogenesis", "activation of apoptotic process involved in morphogenesis", "positive regulation of apoptosis involved in morphogenesis", "up regulation of apoptosis involved in morphogenesis", "up-regulation of apoptosis involved in morphogenesis", "upregulation of apoptosis involved in morphogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of apoptosis involved in development", "activation of morphogenetic apoptosis", "positive regulation of apoptosis involved in development", "positive regulation of morphogenetic apoptosis", "up regulation of apoptosis involved in development", "up regulation of morphogenetic apoptosis", "up-regulation of apoptosis involved in development", "up-regulation of morphogenetic apoptosis", "upregulation of apoptosis involved in development", "upregulation of morphogenetic apoptosis" ; oboInOwl:id "GO:1902339" ; a owl:Class ; rdfs:label "positive regulation of apoptotic process involved in morphogenesis" ; rdfs:subClassOf obo:GO_1902337, obo:GO_1904747, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060561 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060561 ] ) ] . obo:GO_1902340 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation." ; oboInOwl:created_by "dgf" ; oboInOwl:creation_date "2013-07-29T20:54:14Z" ; oboInOwl:hasExactSynonym "down regulation of chromosome condensation", "down regulation of eukaryotic chromosome condensation", "down regulation of nuclear chromosome condensation", "down-regulation of chromosome condensation", "down-regulation of eukaryotic chromosome condensation", "down-regulation of nuclear chromosome condensation", "downregulation of chromosome condensation", "downregulation of eukaryotic chromosome condensation", "downregulation of nuclear chromosome condensation", "negative regulation of eukaryotic chromosome condensation", "negative regulation of nuclear chromosome condensation" ; oboInOwl:hasNarrowSynonym "inhibition of chromosome condensation", "inhibition of eukaryotic chromosome condensation", "inhibition of nuclear chromosome condensation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902340" ; a owl:Class ; rdfs:label "negative regulation of chromosome condensation" ; rdfs:subClassOf obo:GO_0060623, obo:GO_2001251, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030261 ] ) ] . obo:GO_1902369 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2013-08-22T14:59:39Z" ; oboInOwl:hasExactSynonym "down regulation of RNA breakdown", "down regulation of RNA catabolic process", "down regulation of RNA catabolism", "down regulation of RNA degradation", "down-regulation of RNA breakdown", "down-regulation of RNA catabolic process", "down-regulation of RNA catabolism", "down-regulation of RNA degradation", "downregulation of RNA breakdown", "downregulation of RNA catabolic process", "downregulation of RNA catabolism", "downregulation of RNA degradation", "negative regulation of RNA breakdown", "negative regulation of RNA catabolism", "negative regulation of RNA degradation" ; oboInOwl:hasNarrowSynonym "inhibition of RNA breakdown", "inhibition of RNA catabolic process", "inhibition of RNA catabolism", "inhibition of RNA degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902369" ; a owl:Class ; rdfs:label "negative regulation of RNA catabolic process" ; rdfs:subClassOf obo:GO_0031330, obo:GO_0051253, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006401 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006401 ] ) ] . obo:GO_1902373 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2013-08-22T15:16:19Z" ; oboInOwl:hasExactSynonym "down regulation of mRNA breakdown", "down regulation of mRNA catabolic process", "down regulation of mRNA catabolism", "down regulation of mRNA degradation", "down-regulation of mRNA breakdown", "down-regulation of mRNA catabolic process", "down-regulation of mRNA catabolism", "down-regulation of mRNA degradation", "downregulation of mRNA breakdown", "downregulation of mRNA catabolic process", "downregulation of mRNA catabolism", "downregulation of mRNA degradation", "negative regulation of mRNA breakdown", "negative regulation of mRNA catabolism", "negative regulation of mRNA degradation" ; oboInOwl:hasNarrowSynonym "inhibition of mRNA breakdown", "inhibition of mRNA catabolic process", "inhibition of mRNA catabolism", "inhibition of mRNA degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of mRNA decay", "down-regulation of mRNA decay", "downregulation of mRNA decay", "inhibition of mRNA decay", "negative regulation of mRNA decay" ; oboInOwl:id "GO:1902373" ; a owl:Class ; rdfs:label "negative regulation of mRNA catabolic process" ; rdfs:subClassOf obo:GO_0010628, obo:GO_0061013, obo:GO_1902369, obo:GO_1903312, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006402 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006402 ] ) ] . obo:GO_1902412 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic cytokinesis." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-09-12T14:11:49Z" ; oboInOwl:hasExactSynonym "regulation of cytokinesis after mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902412" ; a owl:Class ; rdfs:label "regulation of mitotic cytokinesis" ; rdfs:subClassOf obo:GO_0032465, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000281 ] ) ] . obo:GO_1902413 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2013-09-12T14:11:59Z" ; oboInOwl:hasExactSynonym "down regulation of cytokinesis after mitosis", "down regulation of mitotic cytokinesis", "down-regulation of cytokinesis after mitosis", "down-regulation of mitotic cytokinesis", "downregulation of cytokinesis after mitosis", "downregulation of mitotic cytokinesis", "negative regulation of cytokinesis after mitosis" ; oboInOwl:hasNarrowSynonym "inhibition of cytokinesis after mitosis", "inhibition of mitotic cytokinesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902413" ; a owl:Class ; rdfs:label "negative regulation of mitotic cytokinesis" ; rdfs:subClassOf obo:GO_0032466, obo:GO_1902412, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000281 ] ) ] . obo:GO_1902435 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of male mating behavior." ; oboInOwl:created_by "mm2" ; oboInOwl:creation_date "2013-10-09T15:49:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902435" ; a owl:Class ; rdfs:label "regulation of male mating behavior" ; rdfs:subClassOf obo:GO_0050795, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060179 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060179 ] ) ] . obo:GO_1902436 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior." ; oboInOwl:created_by "mm2" ; oboInOwl:creation_date "2013-10-09T15:50:05Z" ; oboInOwl:hasExactSynonym "down regulation of male mating behavior", "down-regulation of male mating behavior", "downregulation of male mating behavior" ; oboInOwl:hasNarrowSynonym "inhibition of male mating behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902436" ; a owl:Class ; rdfs:label "negative regulation of male mating behavior" ; rdfs:subClassOf obo:GO_0048521, obo:GO_1902435, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060179 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060179 ] ) ] . obo:GO_1902437 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of male mating behavior." ; oboInOwl:created_by "mm2" ; oboInOwl:creation_date "2013-10-09T15:50:14Z" ; oboInOwl:hasExactSynonym "up regulation of male mating behavior", "up-regulation of male mating behavior", "upregulation of male mating behavior" ; oboInOwl:hasNarrowSynonym "activation of male mating behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902437" ; a owl:Class ; rdfs:label "positive regulation of male mating behavior" ; rdfs:subClassOf obo:GO_0048520, obo:GO_1902435, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060179 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060179 ] ) ] . obo:GO_1902513 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of organelle transport along microtubule." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2013-11-15T20:15:17Z" ; oboInOwl:hasExactSynonym "regulation of microtubule-based organelle localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902513" ; a owl:Class ; rdfs:label "regulation of organelle transport along microtubule" ; rdfs:subClassOf obo:GO_0032386, obo:GO_0060632, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072384 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0072384 ] ) ] . obo:GO_1902531 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of intracellular signal transduction." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2013-12-02T11:32:52Z" ; oboInOwl:hasAlternativeId "GO:0010627" ; oboInOwl:hasExactSynonym "regulation of intracellular signaling cascade", "regulation of intracellular signaling chain" ; oboInOwl:hasNarrowSynonym "regulation of intracellular protein kinase cascade", "regulation of intracellular signal transduction pathway", "regulation of signal transmission via intracellular cascade" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of intracellular signaling pathway", "regulation of signal transduction via intracellular signaling cascade" ; oboInOwl:id "GO:1902531" ; a owl:Class ; rdfs:label "regulation of intracellular signal transduction" ; rdfs:subClassOf obo:GO_0009966, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035556 ] ) ] . obo:GO_1902532 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2013-12-02T11:33:01Z" ; oboInOwl:hasAlternativeId "GO:0010741" ; oboInOwl:hasExactSynonym "down regulation of intracellular signal transduction", "down regulation of intracellular signaling chain", "down-regulation of intracellular signal transduction", "down-regulation of intracellular signaling chain", "downregulation of intracellular signal transduction", "downregulation of intracellular signaling chain", "negative regulation of intracellular protein kinase cascade", "negative regulation of intracellular signaling cascade", "negative regulation of intracellular signaling chain" ; oboInOwl:hasNarrowSynonym "down regulation of intracellular signal transduction pathway", "down regulation of intracellular signaling cascade", "down regulation of signal transmission via intracellular cascade", "down-regulation of intracellular signal transduction pathway", "downregulation of intracellular signal transduction pathway", "downregulation of intracellular signaling cascade", "downregulation of signal transmission via intracellular cascade", "inhibition of intracellular signal transduction", "inhibition of intracellular signal transduction pathway", "inhibition of intracellular signaling cascade", "inhibition of intracellular signaling chain", "inhibition of signal transmission via intracellular cascade", "negative regulation of intracellular signal transduction pathway", "negative regulation of signal transmission via intracellular cascade" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of intracellular signaling pathway", "down regulation of signal transduction via intracellular signaling cascade", "down-regulation of intracellular signaling cascade", "down-regulation of intracellular signaling pathway", "down-regulation of signal transduction via intracellular signaling cascade", "down-regulation of signal transmission via intracellular cascade", "downregulation of intracellular signaling pathway", "downregulation of signal transduction via intracellular signaling cascade", "inhibition of intracellular signaling pathway", "inhibition of signal transduction via intracellular signaling cascade", "negative regulation of intracellular signaling pathway", "negative regulation of signal transduction via intracellular signaling cascade" ; oboInOwl:id "GO:1902532" ; a owl:Class ; rdfs:label "negative regulation of intracellular signal transduction" ; rdfs:subClassOf obo:GO_0009968, obo:GO_1902531, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035556 ] ) ] . obo:GO_1902533 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2013-12-02T11:33:10Z" ; oboInOwl:hasAlternativeId "GO:0010740" ; oboInOwl:hasExactSynonym "positive regulation of intracellular signaling chain", "up regulation of intracellular signal transduction", "up regulation of intracellular signaling chain", "up-regulation of intracellular signal transduction", "up-regulation of intracellular signaling chain", "upregulation of intracellular signal transduction", "upregulation of intracellular signaling chain" ; oboInOwl:hasNarrowSynonym "activation of intracellular signal transduction", "activation of intracellular signal transduction pathway", "activation of intracellular signaling cascade", "activation of intracellular signaling chain", "activation of signal transmission via intracellular cascade", "positive regulation of intracellular protein kinase cascade", "positive regulation of intracellular signal transduction pathway", "positive regulation of signal transmission via intracellular cascade", "up regulation of intracellular signal transduction pathway", "up regulation of signal transmission via intracellular cascade", "up-regulation of intracellular signal transduction pathway", "up-regulation of signal transmission via intracellular cascade", "upregulation of intracellular signal transduction pathway", "upregulation of signal transmission via intracellular cascade" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of intracellular signaling pathway", "activation of signal transduction via intracellular signaling cascade", "positive regulation of intracellular signaling cascade", "positive regulation of intracellular signaling pathway", "positive regulation of signal transduction via intracellular signaling cascade", "up regulation of intracellular signaling cascade", "up regulation of intracellular signaling pathway", "up regulation of signal transduction via intracellular signaling cascade", "up-regulation of intracellular signaling cascade", "up-regulation of intracellular signaling pathway", "up-regulation of signal transduction via intracellular signaling cascade", "upregulation of intracellular signaling cascade", "upregulation of intracellular signaling pathway", "upregulation of signal transduction via intracellular signaling cascade" ; oboInOwl:id "GO:1902533" ; a owl:Class ; rdfs:label "positive regulation of intracellular signal transduction" ; rdfs:subClassOf obo:GO_0009967, obo:GO_1902531, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035556 ] ) ] . obo:GO_1902576 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2013-12-17T14:03:02Z" ; oboInOwl:hasExactSynonym "down regulation of DNA replication involved in S phase", "down regulation of DNA replication involved in S-phase", "down regulation of nuclear cell cycle DNA replication", "down-regulation of DNA replication involved in S phase", "down-regulation of DNA replication involved in S-phase", "down-regulation of nuclear cell cycle DNA replication", "downregulation of DNA replication involved in S phase", "downregulation of DNA replication involved in S-phase", "downregulation of nuclear cell cycle DNA replication", "negative regulation of DNA replication involved in S phase", "negative regulation of DNA replication involved in S-phase" ; oboInOwl:hasNarrowSynonym "inhibition of DNA replication involved in S phase", "inhibition of DNA replication involved in S-phase", "inhibition of nuclear cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of DNA replication during S phase", "down-regulation of DNA replication during S phase", "downregulation of DNA replication during S phase", "inhibition of DNA replication during S phase", "negative regulation of DNA replication during S phase" ; oboInOwl:id "GO:1902576" ; a owl:Class ; rdfs:label "negative regulation of nuclear cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0033262, obo:GO_2000104, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0033260 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0033260 ] ) ] . obo:GO_1902584 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of response to water deprivation." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2013-12-19T00:31:58Z" ; oboInOwl:hasExactSynonym "positive regulation of response to dehydration", "positive regulation of response to drought", "positive regulation of response to thirst", "up regulation of response to dehydration", "up regulation of response to drought", "up regulation of response to thirst", "up regulation of response to water deprivation", "up-regulation of response to dehydration", "up-regulation of response to drought", "up-regulation of response to thirst", "up-regulation of response to water deprivation", "upregulation of response to dehydration", "upregulation of response to drought", "upregulation of response to thirst", "upregulation of response to water deprivation" ; oboInOwl:hasNarrowSynonym "activation of response to dehydration", "activation of response to drought", "activation of response to thirst", "activation of response to water deprivation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of drought tolerance", "positive regulation of drought tolerance", "up regulation of drought tolerance", "up-regulation of drought tolerance", "upregulation of drought tolerance" ; oboInOwl:id "GO:1902584" ; a owl:Class ; rdfs:label "positive regulation of response to water deprivation" ; rdfs:subClassOf obo:GO_0048584, obo:GO_2000070, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009414 ] ) ] . obo:GO_1902667 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of axon guidance." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2014-01-31T18:50:10Z" ; oboInOwl:hasExactSynonym "regulation of axon pathfinding" ; oboInOwl:hasNarrowSynonym "regulation of axon growth cone guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of axon chemotaxis" ; oboInOwl:id "GO:1902667" ; a owl:Class ; rdfs:label "regulation of axon guidance" ; rdfs:subClassOf obo:GO_0010975, obo:GO_0050920, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007411 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007411 ] ) ] . obo:GO_1902668 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2014-01-31T18:50:19Z" ; oboInOwl:hasExactSynonym "down regulation of axon guidance", "down regulation of axon pathfinding", "down-regulation of axon guidance", "down-regulation of axon pathfinding", "downregulation of axon guidance", "downregulation of axon pathfinding", "negative regulation of axon pathfinding" ; oboInOwl:hasNarrowSynonym "down regulation of axon growth cone guidance", "down-regulation of axon growth cone guidance", "downregulation of axon growth cone guidance", "inhibition of axon growth cone guidance", "inhibition of axon guidance", "inhibition of axon pathfinding", "negative regulation of axon growth cone guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of axon chemotaxis", "down-regulation of axon chemotaxis", "downregulation of axon chemotaxis", "inhibition of axon chemotaxis", "negative regulation of axon chemotaxis" ; oboInOwl:id "GO:1902668" ; a owl:Class ; rdfs:label "negative regulation of axon guidance" ; rdfs:subClassOf obo:GO_0010977, obo:GO_0050922, obo:GO_1902667, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007411 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007411 ] ) ] . obo:GO_1902669 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of axon guidance." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2014-01-31T18:50:29Z" ; oboInOwl:hasExactSynonym "positive regulation of axon pathfinding", "up regulation of axon guidance", "up regulation of axon pathfinding", "up-regulation of axon guidance", "up-regulation of axon pathfinding", "upregulation of axon guidance", "upregulation of axon pathfinding" ; oboInOwl:hasNarrowSynonym "activation of axon growth cone guidance", "activation of axon guidance", "activation of axon pathfinding", "positive regulation of axon growth cone guidance", "up regulation of axon growth cone guidance", "up-regulation of axon growth cone guidance", "upregulation of axon growth cone guidance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of axon chemotaxis", "positive regulation of axon chemotaxis", "up regulation of axon chemotaxis", "up-regulation of axon chemotaxis", "upregulation of axon chemotaxis" ; oboInOwl:id "GO:1902669" ; a owl:Class ; rdfs:label "positive regulation of axon guidance" ; rdfs:subClassOf obo:GO_0010976, obo:GO_1902667, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007411 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007411 ] ) ] . obo:GO_1902679 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-02-05T16:32:01Z" ; oboInOwl:hasExactSynonym "down regulation of RNA anabolism", "down regulation of RNA biosynthesis", "down regulation of RNA biosynthetic process", "down regulation of RNA formation", "down regulation of RNA synthesis", "down-regulation of RNA anabolism", "down-regulation of RNA biosynthesis", "down-regulation of RNA biosynthetic process", "down-regulation of RNA formation", "down-regulation of RNA synthesis", "downregulation of RNA anabolism", "downregulation of RNA biosynthesis", "downregulation of RNA biosynthetic process", "downregulation of RNA formation", "downregulation of RNA synthesis", "negative regulation of RNA anabolism", "negative regulation of RNA biosynthesis", "negative regulation of RNA formation", "negative regulation of RNA synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of RNA anabolism", "inhibition of RNA biosynthesis", "inhibition of RNA biosynthetic process", "inhibition of RNA formation", "inhibition of RNA synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902679" ; a owl:Class ; rdfs:label "negative regulation of RNA biosynthetic process" ; rdfs:subClassOf obo:GO_0010558, obo:GO_0051253, obo:GO_2001141, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032774 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032774 ] ) ] . obo:GO_1902680 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-02-05T16:32:10Z" ; oboInOwl:hasExactSynonym "positive regulation of RNA anabolism", "positive regulation of RNA biosynthesis", "positive regulation of RNA formation", "positive regulation of RNA synthesis", "up regulation of RNA anabolism", "up regulation of RNA biosynthesis", "up regulation of RNA biosynthetic process", "up regulation of RNA formation", "up regulation of RNA synthesis", "up-regulation of RNA anabolism", "up-regulation of RNA biosynthesis", "up-regulation of RNA biosynthetic process", "up-regulation of RNA formation", "up-regulation of RNA synthesis", "upregulation of RNA anabolism", "upregulation of RNA biosynthesis", "upregulation of RNA biosynthetic process", "upregulation of RNA formation", "upregulation of RNA synthesis" ; oboInOwl:hasNarrowSynonym "activation of RNA anabolism", "activation of RNA biosynthesis", "activation of RNA biosynthetic process", "activation of RNA formation", "activation of RNA synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902680" ; a owl:Class ; rdfs:label "positive regulation of RNA biosynthetic process" ; rdfs:subClassOf obo:GO_0010557, obo:GO_0051254, obo:GO_2001141, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032774 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032774 ] ) ] . obo:GO_1902742 obo:IAO_0000115 "Any apoptotic process that is involved in anatomical structure development." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2014-02-28T13:09:43Z" ; oboInOwl:hasExactSynonym "apoptotic cell death involved in anatomical structure development", "apoptotic cell death involved in development of an anatomical structure", "apoptotic process involved in anatomical structure development", "apoptotic process involved in development of an anatomical structure", "apoptotic programmed cell death involved in anatomical structure development", "apoptotic programmed cell death involved in development of an anatomical structure", "programmed cell death by apoptosis involved in anatomical structure development", "programmed cell death by apoptosis involved in development of an anatomical structure" ; oboInOwl:hasNarrowSynonym "activation of apoptosis involved in anatomical structure development", "activation of apoptosis involved in development of an anatomical structure", "apoptosis involved in anatomical structure development", "apoptosis involved in development of an anatomical structure", "apoptosis signaling involved in anatomical structure development", "apoptosis signaling involved in development of an anatomical structure", "apoptotic program involved in anatomical structure development", "apoptotic program involved in development of an anatomical structure", "type I programmed cell death involved in anatomical structure development", "type I programmed cell death involved in development of an anatomical structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "apoptosis activator activity involved in anatomical structure development", "apoptosis activator activity involved in development of an anatomical structure", "commitment to apoptosis involved in anatomical structure development", "commitment to apoptosis involved in development of an anatomical structure", "induction of apoptosis by p53 involved in anatomical structure development", "induction of apoptosis by p53 involved in development of an anatomical structure", "induction of apoptosis involved in anatomical structure development", "induction of apoptosis involved in development of an anatomical structure", "signaling (initiator) caspase activity involved in anatomical structure development", "signaling (initiator) caspase activity involved in development of an anatomical structure" ; oboInOwl:id "GO:1902742" ; a owl:Class ; rdfs:label "apoptotic process involved in development" ; rdfs:subClassOf obo:GO_0006915, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048856 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006915 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048856 ] ) ] . obo:GO_1902749 obo:IAO_0000115 "Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-05T15:38:15Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902749" ; a owl:Class ; rdfs:label "regulation of cell cycle G2/M phase transition" ; rdfs:subClassOf obo:GO_1901987, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044839 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044839 ] ) ] . obo:GO_1902750 obo:IAO_0000115 "Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-05T15:38:21Z" ; oboInOwl:hasExactSynonym "down regulation of cell cycle G2/M phase transition", "down-regulation of cell cycle G2/M phase transition", "downregulation of cell cycle G2/M phase transition" ; oboInOwl:hasNarrowSynonym "inhibition of cell cycle G2/M phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902750" ; a owl:Class ; rdfs:label "negative regulation of cell cycle G2/M phase transition" ; rdfs:subClassOf obo:GO_1901988, obo:GO_1902749, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044839 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044839 ] ) ] . obo:GO_1902751 obo:IAO_0000115 "Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-05T15:38:27Z" ; oboInOwl:hasExactSynonym "up regulation of cell cycle G2/M phase transition", "up-regulation of cell cycle G2/M phase transition", "upregulation of cell cycle G2/M phase transition" ; oboInOwl:hasNarrowSynonym "activation of cell cycle G2/M phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902751" ; a owl:Class ; rdfs:label "positive regulation of cell cycle G2/M phase transition" ; rdfs:subClassOf obo:GO_1901989, obo:GO_1902749, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044839 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044839 ] ) ] . obo:GO_1902803 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of synaptic vesicle transport." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-03-25T14:56:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of synaptic vesicle fission", "regulation of synaptic vesicle fusion" ; oboInOwl:id "GO:1902803" ; a owl:Class ; rdfs:label "regulation of synaptic vesicle transport" ; rdfs:subClassOf obo:GO_0050794, obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048489 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048489 ] ) ] . obo:GO_1902804 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-03-25T14:56:40Z" ; oboInOwl:hasExactSynonym "down regulation of synaptic vesicle transport", "down-regulation of synaptic vesicle transport", "downregulation of synaptic vesicle transport" ; oboInOwl:hasNarrowSynonym "inhibition of synaptic vesicle transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of synaptic vesicle fission", "down regulation of synaptic vesicle fusion", "down-regulation of synaptic vesicle fission", "down-regulation of synaptic vesicle fusion", "downregulation of synaptic vesicle fission", "downregulation of synaptic vesicle fusion", "inhibition of synaptic vesicle fission", "inhibition of synaptic vesicle fusion", "negative regulation of synaptic vesicle fission", "negative regulation of synaptic vesicle fusion" ; oboInOwl:id "GO:1902804" ; a owl:Class ; rdfs:label "negative regulation of synaptic vesicle transport" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0051051, obo:GO_1902803, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048489 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048489 ] ) ] . obo:GO_1902805 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-03-25T14:56:46Z" ; oboInOwl:hasExactSynonym "up regulation of synaptic vesicle transport", "up-regulation of synaptic vesicle transport", "upregulation of synaptic vesicle transport" ; oboInOwl:hasNarrowSynonym "activation of synaptic vesicle transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of synaptic vesicle fission", "activation of synaptic vesicle fusion", "positive regulation of synaptic vesicle fission", "positive regulation of synaptic vesicle fusion", "up regulation of synaptic vesicle fission", "up regulation of synaptic vesicle fusion", "up-regulation of synaptic vesicle fission", "up-regulation of synaptic vesicle fusion", "upregulation of synaptic vesicle fission", "upregulation of synaptic vesicle fusion" ; oboInOwl:id "GO:1902805" ; a owl:Class ; rdfs:label "positive regulation of synaptic vesicle transport" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0051050, obo:GO_1902803, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048489 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048489 ] ) ] . obo:GO_1902806 obo:IAO_0000115 "Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-26T16:36:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902806" ; a owl:Class ; rdfs:label "regulation of cell cycle G1/S phase transition" ; rdfs:subClassOf obo:GO_1901987, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044843 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044843 ] ) ] . obo:GO_1902807 obo:IAO_0000115 "Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-26T16:36:20Z" ; oboInOwl:hasExactSynonym "down regulation of cell cycle G1/S phase transition", "down-regulation of cell cycle G1/S phase transition", "downregulation of cell cycle G1/S phase transition" ; oboInOwl:hasNarrowSynonym "inhibition of cell cycle G1/S phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902807" ; a owl:Class ; rdfs:label "negative regulation of cell cycle G1/S phase transition" ; rdfs:subClassOf obo:GO_1901988, obo:GO_1902806, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044843 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044843 ] ) ] . obo:GO_1902808 obo:IAO_0000115 "Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-03-26T16:36:32Z" ; oboInOwl:hasExactSynonym "up regulation of cell cycle G1/S phase transition", "up-regulation of cell cycle G1/S phase transition", "upregulation of cell cycle G1/S phase transition" ; oboInOwl:hasNarrowSynonym "activation of cell cycle G1/S phase transition" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902808" ; a owl:Class ; rdfs:label "positive regulation of cell cycle G1/S phase transition" ; rdfs:subClassOf obo:GO_1901989, obo:GO_1902806, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044843 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044843 ] ) ] . obo:GO_1902845 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-04-02T08:43:28Z" ; oboInOwl:hasExactSynonym "down regulation of mitotic spindle elongation", "down regulation of spindle elongation during mitosis", "down-regulation of mitotic spindle elongation", "down-regulation of spindle elongation during mitosis", "downregulation of mitotic spindle elongation", "downregulation of spindle elongation during mitosis", "negative regulation of spindle elongation during mitosis" ; oboInOwl:hasNarrowSynonym "inhibition of mitotic spindle elongation", "inhibition of spindle elongation during mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902845" ; a owl:Class ; rdfs:label "negative regulation of mitotic spindle elongation" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0032888, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000022 ] ) ] . obo:GO_1902846 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-04-02T08:43:34Z" ; oboInOwl:hasExactSynonym "positive regulation of spindle elongation during mitosis", "up regulation of mitotic spindle elongation", "up regulation of spindle elongation during mitosis", "up-regulation of mitotic spindle elongation", "up-regulation of spindle elongation during mitosis", "upregulation of mitotic spindle elongation", "upregulation of spindle elongation during mitosis" ; oboInOwl:hasNarrowSynonym "activation of mitotic spindle elongation", "activation of spindle elongation during mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902846" ; a owl:Class ; rdfs:label "positive regulation of mitotic spindle elongation" ; rdfs:subClassOf obo:GO_0032888, obo:GO_0062033, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000022 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000022 ] ) ] . obo:GO_1902850 obo:IAO_0000115 "Any microtubule cytoskeleton organization that is involved in mitosis." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-04-02T14:19:38Z" ; oboInOwl:hasExactSynonym "microtubule cytoskeleton organisation involved in mitosis", "microtubule dynamics involved in mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "microtubule cytoskeleton organization and biogenesis involved in mitosis" ; oboInOwl:id "GO:1902850" ; a owl:Class ; rdfs:label "microtubule cytoskeleton organization involved in mitosis" ; rdfs:subClassOf obo:GO_0000226, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000226 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_1902882 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of response to oxidative stress." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-04-03T20:29:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902882" ; a owl:Class ; rdfs:label "regulation of response to oxidative stress" ; rdfs:subClassOf obo:GO_0080134, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006979 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006979 ] ) ] . obo:GO_1902883 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-04-03T20:30:20Z" ; oboInOwl:hasExactSynonym "down regulation of response to oxidative stress", "down-regulation of response to oxidative stress", "downregulation of response to oxidative stress" ; oboInOwl:hasNarrowSynonym "inhibition of response to oxidative stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902883" ; a owl:Class ; rdfs:label "negative regulation of response to oxidative stress" ; rdfs:subClassOf obo:GO_0048585, obo:GO_1902882, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006979 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006979 ] ) ] . obo:GO_1902884 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of response to oxidative stress." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-04-03T20:30:47Z" ; oboInOwl:hasExactSynonym "up regulation of response to oxidative stress", "up-regulation of response to oxidative stress", "upregulation of response to oxidative stress" ; oboInOwl:hasNarrowSynonym "activation of response to oxidative stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902884" ; a owl:Class ; rdfs:label "positive regulation of response to oxidative stress" ; rdfs:subClassOf obo:GO_0048584, obo:GO_1902882, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006979 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006979 ] ) ] . obo:GO_1902903 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of supramolecular fiber organization." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2014-04-15T16:46:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of fibril organisation" ; oboInOwl:id "GO:1902903" ; a owl:Class ; rdfs:comment "HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro" ; rdfs:label "regulation of supramolecular fiber organization" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097435 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097435 ] ) ] . obo:GO_1902904 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2014-04-15T16:46:42Z" ; oboInOwl:hasNarrowSynonym "inhibition of fibril organisation", "inhibition of fibril organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of fibril organisation", "down regulation of fibril organization", "down-regulation of fibril organisation", "down-regulation of fibril organization", "downregulation of fibril organisation", "downregulation of fibril organization", "negative regulation of fibril organisation" ; oboInOwl:id "GO:1902904" ; a owl:Class ; rdfs:comment "HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro" ; rdfs:label "negative regulation of supramolecular fiber organization" ; rdfs:subClassOf obo:GO_0051129, obo:GO_1902903, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097435 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097435 ] ) ] . obo:GO_1902905 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2014-04-15T16:46:48Z" ; oboInOwl:hasNarrowSynonym "activation of fibril organisation", "activation of fibril organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of fibril organisation", "up regulation of fibril organisation", "up regulation of fibril organization", "up-regulation of fibril organisation", "up-regulation of fibril organization", "upregulation of fibril organisation", "upregulation of fibril organization" ; oboInOwl:id "GO:1902905" ; a owl:Class ; rdfs:comment "HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro" ; rdfs:label "positive regulation of supramolecular fiber organization" ; rdfs:subClassOf obo:GO_0051130, obo:GO_1902903, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097435 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097435 ] ) ] . obo:GO_1902969 obo:IAO_0000115 "Any nuclear DNA replication that is involved in a mitotic cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-05-06T15:03:03Z" ; oboInOwl:hasExactSynonym "DNA replication involved in S phase involved in mitotic cell cycle", "DNA replication involved in S-phase involved in mitotic cell cycle", "mitotic cell cycle DNA replication", "mitotic nuclear cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA replication during S phase involved in mitotic cell cycle", "nuclear cell cycle DNA replication involved in mitotic cell cycle" ; oboInOwl:id "GO:1902969" ; a owl:Class ; rdfs:label "mitotic DNA replication" ; rdfs:subClassOf obo:GO_0033260, obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0033260 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_1902974 obo:IAO_0000115 "Any DNA replication initiation involved in meiotic cell cycle DNA replication." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-05-06T15:21:06Z" ; oboInOwl:hasAlternativeId "GO:0072691" ; oboInOwl:hasExactSynonym "DNA replication initiation involved in meiotic DNA replication", "DNA replication initiation involved in meiotic cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "initiation of meiotic DNA synthesis", "initiation of premeiotic DNA replication", "initiation of premeiotic DNA synthesis", "premeiotic DNA replication initiation" ; oboInOwl:id "GO:1902974" ; a owl:Class ; rdfs:label "meiotic DNA replication initiation" ; rdfs:subClassOf obo:GO_1902315, obo:GO_1903046 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_1902315 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_1902975 obo:IAO_0000115 "Any DNA replication initiation involved in mitotic cell cycle DNA replication." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-05-06T15:21:11Z" ; oboInOwl:hasExactSynonym "DNA replication initiation involved in mitotic cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1902975" ; a owl:Class ; rdfs:label "mitotic DNA replication initiation" ; rdfs:subClassOf obo:GO_1902315, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_1902969 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_1902315 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_1902969 ] ) ] . obo:GO_1903008 obo:IAO_0000115 "The disaggregation of an organelle into its constituent components." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-05-13T12:36:03Z" ; oboInOwl:hasExactSynonym "organelle degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903008" ; a owl:Class ; rdfs:label "organelle disassembly" ; rdfs:subClassOf obo:GO_0006996, obo:GO_0022411 . obo:GO_1903034 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of response to wounding." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-05-18T01:28:46Z" ; oboInOwl:hasExactSynonym "regulation of physiological response to wounding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903034" ; a owl:Class ; rdfs:label "regulation of response to wounding" ; rdfs:subClassOf obo:GO_0080134, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009611 ] ) ] . obo:GO_1903035 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-05-18T01:28:52Z" ; oboInOwl:hasExactSynonym "down regulation of physiological response to wounding", "down regulation of response to wounding", "down-regulation of physiological response to wounding", "down-regulation of response to wounding", "downregulation of physiological response to wounding", "downregulation of response to wounding", "negative regulation of physiological response to wounding" ; oboInOwl:hasNarrowSynonym "inhibition of physiological response to wounding", "inhibition of response to wounding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903035" ; a owl:Class ; rdfs:label "negative regulation of response to wounding" ; rdfs:subClassOf obo:GO_0048585, obo:GO_1903034, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0009611 ] ) ] . obo:GO_1903036 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of response to wounding." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-05-18T01:28:58Z" ; oboInOwl:hasExactSynonym "positive regulation of physiological response to wounding", "up regulation of physiological response to wounding", "up regulation of response to wounding", "up-regulation of physiological response to wounding", "up-regulation of response to wounding", "upregulation of physiological response to wounding", "upregulation of response to wounding" ; oboInOwl:hasNarrowSynonym "activation of physiological response to wounding", "activation of response to wounding" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903036" ; a owl:Class ; rdfs:label "positive regulation of response to wounding" ; rdfs:subClassOf obo:GO_0048584, obo:GO_1903034, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009611 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009611 ] ) ] . obo:GO_1903046 obo:IAO_0000115 "A process that is part of the meiotic cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-05-22T14:22:28Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903046" ; oboInOwl:inSubset go:gocheck_do_not_annotate, go:goslim_pombe ; a owl:Class ; rdfs:label "meiotic cell cycle process" ; rdfs:subClassOf obo:GO_0022402, obo:GO_0022414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ; owl:disjointWith obo:GO_1903047 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0051321 ] ) ] . obo:GO_1903047 obo:IAO_0000115 "A process that is part of the mitotic cell cycle." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-05-22T14:22:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903047" ; oboInOwl:inSubset go:gocheck_do_not_annotate ; a owl:Class ; rdfs:label "mitotic cell cycle process" ; rdfs:subClassOf obo:GO_0022402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0009987 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0000278 ] ) ] . obo:GO_1903108 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2014-06-09T11:53:14Z" ; oboInOwl:hasExactSynonym "regulation of transcription from mitochondrial promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903108" ; a owl:Class ; rdfs:label "regulation of mitochondrial transcription" ; rdfs:subClassOf obo:GO_0006355, obo:GO_0062125, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006390 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006390 ] ) ] . obo:GO_1903109 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of transcription occuring in the mitochondrion." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2014-06-09T11:53:20Z" ; oboInOwl:hasExactSynonym "positive regulation of transcription from mitochondrial promoter", "up regulation of mitochondrial transcription", "up regulation of transcription from mitochondrial promoter", "up-regulation of mitochondrial transcription", "up-regulation of transcription from mitochondrial promoter", "upregulation of mitochondrial transcription", "upregulation of transcription from mitochondrial promoter" ; oboInOwl:hasNarrowSynonym "activation of mitochondrial transcription", "activation of transcription from mitochondrial promoter" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903109" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial transcription" ; rdfs:subClassOf obo:GO_0045893, obo:GO_1903108, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006390 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006390 ] ) ] . obo:GO_1903146 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-07-09T08:23:51Z" ; oboInOwl:hasBroadSynonym "regulation of mitochondrion degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903146" ; a owl:Class ; rdfs:label "regulation of autophagy of mitochondrion" ; rdfs:subClassOf obo:GO_0010506, obo:GO_0010821, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000422 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000422 ] ) ] . obo:GO_1903147 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-07-09T08:23:58Z" ; oboInOwl:hasBroadSynonym "down regulation of mitochondrial degradation", "down regulation of mitochondrion degradation", "down-regulation of mitochondrion degradation", "down-regulation of mitophagy", "downregulation of mitochondrion degradation" ; oboInOwl:hasNarrowSynonym "inhibition of mitophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "inhibition of mitochondrion degradation" ; oboInOwl:id "GO:1903147" ; a owl:Class ; rdfs:label "negative regulation of autophagy of mitochondrion" ; rdfs:subClassOf obo:GO_0010507, obo:GO_0010823, obo:GO_1903146, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000422 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000422 ] ) ] . obo:GO_1903179 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of dopamine biosynthetic process." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-07-14T12:17:41Z" ; oboInOwl:hasExactSynonym "regulation of dopamine anabolism", "regulation of dopamine biosynthesis", "regulation of dopamine formation", "regulation of dopamine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903179" ; a owl:Class ; rdfs:label "regulation of dopamine biosynthetic process" ; rdfs:subClassOf obo:GO_0031326, obo:GO_0042053, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042416 ] ) ] . obo:GO_1903180 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-07-14T12:17:47Z" ; oboInOwl:hasExactSynonym "down regulation of dopamine anabolism", "down regulation of dopamine biosynthesis", "down regulation of dopamine biosynthetic process", "down regulation of dopamine formation", "down regulation of dopamine synthesis", "down-regulation of dopamine anabolism", "down-regulation of dopamine biosynthesis", "down-regulation of dopamine biosynthetic process", "down-regulation of dopamine formation", "down-regulation of dopamine synthesis", "downregulation of dopamine anabolism", "downregulation of dopamine biosynthesis", "downregulation of dopamine biosynthetic process", "downregulation of dopamine formation", "downregulation of dopamine synthesis", "negative regulation of dopamine anabolism", "negative regulation of dopamine biosynthesis", "negative regulation of dopamine formation", "negative regulation of dopamine synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of dopamine anabolism", "inhibition of dopamine biosynthesis", "inhibition of dopamine biosynthetic process", "inhibition of dopamine formation", "inhibition of dopamine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903180" ; a owl:Class ; rdfs:label "negative regulation of dopamine biosynthetic process" ; rdfs:subClassOf obo:GO_0031327, obo:GO_0045963, obo:GO_1903179, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042416 ] ) ] . obo:GO_1903181 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-07-14T12:17:53Z" ; oboInOwl:hasExactSynonym "positive regulation of dopamine anabolism", "positive regulation of dopamine biosynthesis", "positive regulation of dopamine formation", "positive regulation of dopamine synthesis", "up regulation of dopamine anabolism", "up regulation of dopamine biosynthesis", "up regulation of dopamine biosynthetic process", "up regulation of dopamine formation", "up regulation of dopamine synthesis", "up-regulation of dopamine anabolism", "up-regulation of dopamine biosynthesis", "up-regulation of dopamine biosynthetic process", "up-regulation of dopamine formation", "up-regulation of dopamine synthesis", "upregulation of dopamine anabolism", "upregulation of dopamine biosynthesis", "upregulation of dopamine biosynthetic process", "upregulation of dopamine formation", "upregulation of dopamine synthesis" ; oboInOwl:hasNarrowSynonym "activation of dopamine anabolism", "activation of dopamine biosynthesis", "activation of dopamine biosynthetic process", "activation of dopamine formation", "activation of dopamine synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903181" ; a owl:Class ; rdfs:label "positive regulation of dopamine biosynthetic process" ; rdfs:subClassOf obo:GO_0031328, obo:GO_0045964, obo:GO_1903179, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042416 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042416 ] ) ] . obo:GO_1903186 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of vitellogenesis." ; oboInOwl:created_by "mr" ; oboInOwl:creation_date "2014-07-14T19:28:00Z" ; oboInOwl:hasExactSynonym "regulation of yolk production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903186" ; a owl:Class ; rdfs:label "regulation of vitellogenesis" ; rdfs:subClassOf obo:GO_0051128, obo:GO_0051239, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007296 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007296 ] ) ] . obo:GO_1903187 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis." ; oboInOwl:created_by "mr" ; oboInOwl:creation_date "2014-07-14T19:28:06Z" ; oboInOwl:hasExactSynonym "down regulation of vitellogenesis", "down regulation of yolk production", "down-regulation of vitellogenesis", "down-regulation of yolk production", "downregulation of vitellogenesis", "downregulation of yolk production", "negative regulation of yolk production" ; oboInOwl:hasNarrowSynonym "inhibition of vitellogenesis", "inhibition of yolk production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903187" ; a owl:Class ; rdfs:label "negative regulation of vitellogenesis" ; rdfs:subClassOf obo:GO_0051129, obo:GO_0051241, obo:GO_1903186, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007296 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007296 ] ) ] . obo:GO_1903188 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of vitellogenesis." ; oboInOwl:created_by "mr" ; oboInOwl:creation_date "2014-07-14T19:28:12Z" ; oboInOwl:hasExactSynonym "positive regulation of yolk production", "up regulation of vitellogenesis", "up regulation of yolk production", "up-regulation of vitellogenesis", "up-regulation of yolk production", "upregulation of vitellogenesis", "upregulation of yolk production" ; oboInOwl:hasNarrowSynonym "activation of vitellogenesis", "activation of yolk production" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903188" ; a owl:Class ; rdfs:label "positive regulation of vitellogenesis" ; rdfs:subClassOf obo:GO_0051130, obo:GO_0051240, obo:GO_1903186, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007296 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007296 ] ) ] . obo:GO_1903305 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of regulated secretory pathway." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2014-08-18T10:04:53Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903305" ; a owl:Class ; rdfs:comment "An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype." ; rdfs:label "regulation of regulated secretory pathway" ; rdfs:subClassOf obo:GO_0017157, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045055 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0045055 ] ) ] . obo:GO_1903306 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2014-08-18T10:05:02Z" ; oboInOwl:hasExactSynonym "down regulation of regulated secretory pathway", "down-regulation of regulated secretory pathway", "downregulation of regulated secretory pathway" ; oboInOwl:hasNarrowSynonym "inhibition of regulated secretory pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903306" ; a owl:Class ; rdfs:comment "An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype." ; rdfs:label "negative regulation of regulated secretory pathway" ; rdfs:subClassOf obo:GO_0045920, obo:GO_1903305, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045055 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045055 ] ) ] . obo:GO_1903307 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of regulated secretory pathway." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2014-08-18T10:05:10Z" ; oboInOwl:hasExactSynonym "up regulation of regulated secretory pathway", "up-regulation of regulated secretory pathway", "upregulation of regulated secretory pathway" ; oboInOwl:hasNarrowSynonym "activation of regulated secretory pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903307" ; a owl:Class ; rdfs:comment "An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype." ; rdfs:label "positive regulation of regulated secretory pathway" ; rdfs:subClassOf obo:GO_0045921, obo:GO_1903305, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045055 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045055 ] ) ] . obo:GO_1903311 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mRNA metabolic process." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-08-18T11:52:26Z" ; oboInOwl:hasExactSynonym "regulation of mRNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903311" ; a owl:Class ; rdfs:label "regulation of mRNA metabolic process" ; rdfs:subClassOf obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016071 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016071 ] ) ] . obo:GO_1903312 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-08-18T11:52:34Z" ; oboInOwl:hasExactSynonym "down regulation of mRNA metabolic process", "down regulation of mRNA metabolism", "down-regulation of mRNA metabolic process", "down-regulation of mRNA metabolism", "downregulation of mRNA metabolic process", "downregulation of mRNA metabolism", "negative regulation of mRNA metabolism" ; oboInOwl:hasNarrowSynonym "inhibition of mRNA metabolic process", "inhibition of mRNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903312" ; a owl:Class ; rdfs:label "negative regulation of mRNA metabolic process" ; rdfs:subClassOf obo:GO_0051253, obo:GO_1903311, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016071 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016071 ] ) ] . obo:GO_1903313 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mRNA metabolic process." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-08-18T11:52:42Z" ; oboInOwl:hasExactSynonym "positive regulation of mRNA metabolism", "up regulation of mRNA metabolic process", "up regulation of mRNA metabolism", "up-regulation of mRNA metabolic process", "up-regulation of mRNA metabolism", "upregulation of mRNA metabolic process", "upregulation of mRNA metabolism" ; oboInOwl:hasNarrowSynonym "activation of mRNA metabolic process", "activation of mRNA metabolism" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903313" ; a owl:Class ; rdfs:label "positive regulation of mRNA metabolic process" ; rdfs:subClassOf obo:GO_0051254, obo:GO_1903311, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016071 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016071 ] ) ] . obo:GO_1903353 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of nucleus organization." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2014-08-20T19:36:16Z" ; oboInOwl:hasExactSynonym "regulation of nuclear organisation", "regulation of nuclear organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of nuclear morphology", "regulation of nuclear organization and biogenesis", "regulation of nucleus organization and biogenesis" ; oboInOwl:id "GO:1903353" ; a owl:Class ; rdfs:label "regulation of nucleus organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006997 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0006997 ] ) ] . obo:GO_1903368 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of foraging behavior." ; oboInOwl:created_by "mr" ; oboInOwl:creation_date "2014-08-22T03:03:04Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903368" ; a owl:Class ; rdfs:label "regulation of foraging behavior" ; rdfs:subClassOf obo:GO_0050795, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060756 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0060756 ] ) ] . obo:GO_1903369 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior." ; oboInOwl:created_by "mr" ; oboInOwl:creation_date "2014-08-22T03:03:12Z" ; oboInOwl:hasExactSynonym "down regulation of foraging behavior", "down-regulation of foraging behavior", "downregulation of foraging behavior" ; oboInOwl:hasNarrowSynonym "inhibition of foraging behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903369" ; a owl:Class ; rdfs:label "negative regulation of foraging behavior" ; rdfs:subClassOf obo:GO_0048521, obo:GO_1903368, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060756 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0060756 ] ) ] . obo:GO_1903370 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of foraging behavior." ; oboInOwl:created_by "mr" ; oboInOwl:creation_date "2014-08-22T03:03:20Z" ; oboInOwl:hasExactSynonym "up regulation of foraging behavior", "up-regulation of foraging behavior", "upregulation of foraging behavior" ; oboInOwl:hasNarrowSynonym "activation of foraging behavior" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903370" ; a owl:Class ; rdfs:label "positive regulation of foraging behavior" ; rdfs:subClassOf obo:GO_0048520, obo:GO_1903368, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060756 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0060756 ] ) ] . obo:GO_1903379 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2014-08-26T13:57:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903379" ; a owl:Class ; rdfs:label "regulation of mitotic chromosome condensation" ; rdfs:subClassOf obo:GO_0010564, obo:GO_0060623, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007076 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007076 ] ) ] . obo:GO_1903380 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2014-08-26T13:57:29Z" ; oboInOwl:hasExactSynonym "up regulation of mitotic chromosome condensation", "up-regulation of mitotic chromosome condensation", "upregulation of mitotic chromosome condensation" ; oboInOwl:hasNarrowSynonym "activation of mitotic chromosome condensation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903380" ; a owl:Class ; rdfs:label "positive regulation of mitotic chromosome condensation" ; rdfs:subClassOf obo:GO_0090068, obo:GO_1903379, obo:GO_1905821, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007076 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007076 ] ) ] . obo:GO_1903421 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of synaptic vesicle recycling." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2014-09-09T15:27:50Z" ; oboInOwl:hasNarrowSynonym "regulation of kiss-and-run synaptic vesicle recycling", "regulation of kiss-and-stay synaptic vesicle recycling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903421" ; a owl:Class ; rdfs:comment "An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype" ; rdfs:label "regulation of synaptic vesicle recycling" ; rdfs:subClassOf obo:GO_0051049, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0036465 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0036465 ] ) ] . obo:GO_1903422 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2014-09-09T15:27:59Z" ; oboInOwl:hasExactSynonym "down regulation of synaptic vesicle recycling", "down-regulation of synaptic vesicle recycling", "downregulation of synaptic vesicle recycling" ; oboInOwl:hasNarrowSynonym "down regulation of kiss-and-run synaptic vesicle recycling", "down regulation of kiss-and-stay synaptic vesicle recycling", "down-regulation of kiss-and-run synaptic vesicle recycling", "down-regulation of kiss-and-stay synaptic vesicle recycling", "downregulation of kiss-and-run synaptic vesicle recycling", "downregulation of kiss-and-stay synaptic vesicle recycling", "inhibition of kiss-and-run synaptic vesicle recycling", "inhibition of kiss-and-stay synaptic vesicle recycling", "inhibition of synaptic vesicle recycling", "negative regulation of kiss-and-run synaptic vesicle recycling", "negative regulation of kiss-and-stay synaptic vesicle recycling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903422" ; a owl:Class ; rdfs:comment "An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype" ; rdfs:label "negative regulation of synaptic vesicle recycling" ; rdfs:subClassOf obo:GO_0051051, obo:GO_1903421, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0036465 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0036465 ] ) ] . obo:GO_1903423 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2014-09-09T15:28:07Z" ; oboInOwl:hasExactSynonym "up regulation of synaptic vesicle recycling", "up-regulation of synaptic vesicle recycling", "upregulation of synaptic vesicle recycling" ; oboInOwl:hasNarrowSynonym "activation of kiss-and-run synaptic vesicle recycling", "activation of kiss-and-stay synaptic vesicle recycling", "activation of synaptic vesicle recycling", "positive regulation of kiss-and-run synaptic vesicle recycling", "positive regulation of kiss-and-stay synaptic vesicle recycling", "up regulation of kiss-and-run synaptic vesicle recycling", "up regulation of kiss-and-stay synaptic vesicle recycling", "up-regulation of kiss-and-run synaptic vesicle recycling", "up-regulation of kiss-and-stay synaptic vesicle recycling", "upregulation of kiss-and-run synaptic vesicle recycling", "upregulation of kiss-and-stay synaptic vesicle recycling" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903423" ; a owl:Class ; rdfs:comment "An example of this is mouse LRRK2 (Q5S006) in PMID:21307259 inferred from mutant phenotype" ; rdfs:label "positive regulation of synaptic vesicle recycling" ; rdfs:subClassOf obo:GO_0051050, obo:GO_1903421, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0036465 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0036465 ] ) ] . obo:GO_1903429 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell maturation." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-09-15T13:31:23Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of functional differentiation" ; oboInOwl:id "GO:1903429" ; a owl:Class ; rdfs:label "regulation of cell maturation" ; rdfs:subClassOf obo:GO_0060284, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048469 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048469 ] ) ] . obo:GO_1903430 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-09-15T13:31:32Z" ; oboInOwl:hasExactSynonym "down regulation of cell maturation", "down-regulation of cell maturation", "downregulation of cell maturation" ; oboInOwl:hasNarrowSynonym "inhibition of cell maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of functional differentiation", "down-regulation of functional differentiation", "downregulation of functional differentiation", "inhibition of functional differentiation", "negative regulation of functional differentiation" ; oboInOwl:id "GO:1903430" ; a owl:Class ; rdfs:label "negative regulation of cell maturation" ; rdfs:subClassOf obo:GO_0010721, obo:GO_1903429, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048469 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048469 ] ) ] . obo:GO_1903431 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell maturation." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-09-15T13:31:41Z" ; oboInOwl:hasExactSynonym "up regulation of cell maturation", "up-regulation of cell maturation", "upregulation of cell maturation" ; oboInOwl:hasNarrowSynonym "activation of cell maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of functional differentiation", "positive regulation of functional differentiation", "up regulation of functional differentiation", "up-regulation of functional differentiation", "upregulation of functional differentiation" ; oboInOwl:id "GO:1903431" ; a owl:Class ; rdfs:label "positive regulation of cell maturation" ; rdfs:subClassOf obo:GO_0010720, obo:GO_1903429, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048469 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048469 ] ) ] . obo:GO_1903463 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-09-23T13:38:25Z" ; oboInOwl:hasExactSynonym "regulation of DNA replication involved in S phase involved in mitotic cell cycle", "regulation of DNA replication involved in S-phase involved in mitotic cell cycle", "regulation of mitotic nuclear cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of DNA replication during S phase involved in mitotic cell cycle", "regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" ; oboInOwl:id "GO:1903463" ; a owl:Class ; rdfs:label "regulation of mitotic cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0007346, obo:GO_0033262, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1902969 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1902969 ] ) ] . obo:GO_1903464 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-09-23T13:38:33Z" ; oboInOwl:hasExactSynonym "down regulation of DNA replication involved in S phase involved in mitotic cell cycle", "down regulation of DNA replication involved in S-phase involved in mitotic cell cycle", "down regulation of mitotic cell cycle DNA replication", "down regulation of mitotic nuclear cell cycle DNA replication", "down-regulation of DNA replication involved in S phase involved in mitotic cell cycle", "down-regulation of DNA replication involved in S-phase involved in mitotic cell cycle", "down-regulation of mitotic cell cycle DNA replication", "down-regulation of mitotic nuclear cell cycle DNA replication", "downregulation of DNA replication involved in S phase involved in mitotic cell cycle", "downregulation of DNA replication involved in S-phase involved in mitotic cell cycle", "downregulation of mitotic cell cycle DNA replication", "downregulation of mitotic nuclear cell cycle DNA replication", "negative regulation of DNA replication involved in S phase involved in mitotic cell cycle", "negative regulation of DNA replication involved in S-phase involved in mitotic cell cycle", "negative regulation of mitotic nuclear cell cycle DNA replication" ; oboInOwl:hasNarrowSynonym "inhibition of DNA replication involved in S phase involved in mitotic cell cycle", "inhibition of DNA replication involved in S-phase involved in mitotic cell cycle", "inhibition of mitotic cell cycle DNA replication", "inhibition of mitotic nuclear cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of DNA replication during S phase involved in mitotic cell cycle", "down regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle", "down-regulation of DNA replication during S phase involved in mitotic cell cycle", "down-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle", "downregulation of DNA replication during S phase involved in mitotic cell cycle", "downregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle", "inhibition of DNA replication during S phase involved in mitotic cell cycle", "inhibition of nuclear cell cycle DNA replication involved in mitotic cell cycle", "negative regulation of DNA replication during S phase involved in mitotic cell cycle", "negative regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" ; oboInOwl:id "GO:1903464" ; a owl:Class ; rdfs:label "negative regulation of mitotic cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0045930, obo:GO_1902576, obo:GO_1903463, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1902969 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1902969 ] ) ] . obo:GO_1903465 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-09-23T13:38:41Z" ; oboInOwl:hasExactSynonym "positive regulation of DNA replication involved in S phase involved in mitotic cell cycle", "positive regulation of DNA replication involved in S-phase involved in mitotic cell cycle", "positive regulation of mitotic nuclear cell cycle DNA replication", "up regulation of DNA replication involved in S phase involved in mitotic cell cycle", "up regulation of DNA replication involved in S-phase involved in mitotic cell cycle", "up regulation of mitotic cell cycle DNA replication", "up regulation of mitotic nuclear cell cycle DNA replication", "up-regulation of DNA replication involved in S phase involved in mitotic cell cycle", "up-regulation of DNA replication involved in S-phase involved in mitotic cell cycle", "up-regulation of mitotic cell cycle DNA replication", "up-regulation of mitotic nuclear cell cycle DNA replication", "upregulation of DNA replication involved in S phase involved in mitotic cell cycle", "upregulation of DNA replication involved in S-phase involved in mitotic cell cycle", "upregulation of mitotic cell cycle DNA replication", "upregulation of mitotic nuclear cell cycle DNA replication" ; oboInOwl:hasNarrowSynonym "activation of DNA replication involved in S phase involved in mitotic cell cycle", "activation of DNA replication involved in S-phase involved in mitotic cell cycle", "activation of mitotic cell cycle DNA replication", "activation of mitotic nuclear cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of DNA replication during S phase involved in mitotic cell cycle", "activation of nuclear cell cycle DNA replication involved in mitotic cell cycle", "positive regulation of DNA replication during S phase involved in mitotic cell cycle", "positive regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle", "up regulation of DNA replication during S phase involved in mitotic cell cycle", "up regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle", "up-regulation of DNA replication during S phase involved in mitotic cell cycle", "up-regulation of nuclear cell cycle DNA replication involved in mitotic cell cycle", "upregulation of DNA replication during S phase involved in mitotic cell cycle", "upregulation of nuclear cell cycle DNA replication involved in mitotic cell cycle" ; oboInOwl:id "GO:1903465" ; a owl:Class ; rdfs:label "positive regulation of mitotic cell cycle DNA replication" ; rdfs:subClassOf obo:GO_0010571, obo:GO_0045931, obo:GO_1903463, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1902969 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1902969 ] ) ] . obo:GO_1903466 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-09-23T13:38:49Z" ; oboInOwl:hasExactSynonym "regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903466" ; a owl:Class ; rdfs:label "regulation of mitotic DNA replication initiation" ; rdfs:subClassOf obo:GO_0030174, obo:GO_1903463, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1902975 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1902975 ] ) ] . obo:GO_1903467 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-09-23T13:38:58Z" ; oboInOwl:hasExactSynonym "down regulation of DNA replication initiation involved in mitotic DNA replication", "down regulation of DNA replication initiation involved in mitotic cell cycle DNA replication", "down-regulation of DNA replication initiation involved in mitotic DNA replication", "down-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication", "downregulation of DNA replication initiation involved in mitotic DNA replication", "downregulation of DNA replication initiation involved in mitotic cell cycle DNA replication", "negative regulation of DNA replication initiation involved in mitotic cell cycle DNA replication" ; oboInOwl:hasNarrowSynonym "inhibition of DNA replication initiation involved in mitotic DNA replication", "inhibition of DNA replication initiation involved in mitotic cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903467" ; a owl:Class ; rdfs:label "negative regulation of mitotic DNA replication initiation" ; rdfs:subClassOf obo:GO_0032297, obo:GO_1903464, obo:GO_1903466, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1902975 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1902975 ] ) ] . obo:GO_1903468 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-09-23T13:39:06Z" ; oboInOwl:hasExactSynonym "positive regulation of DNA replication initiation involved in mitotic cell cycle DNA replication", "up regulation of DNA replication initiation involved in mitotic DNA replication", "up regulation of DNA replication initiation involved in mitotic cell cycle DNA replication", "up-regulation of DNA replication initiation involved in mitotic DNA replication", "up-regulation of DNA replication initiation involved in mitotic cell cycle DNA replication", "upregulation of DNA replication initiation involved in mitotic DNA replication", "upregulation of DNA replication initiation involved in mitotic cell cycle DNA replication" ; oboInOwl:hasNarrowSynonym "activation of DNA replication initiation involved in mitotic DNA replication", "activation of DNA replication initiation involved in mitotic cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903468" ; a owl:Class ; rdfs:label "positive regulation of DNA replication initiation" ; rdfs:subClassOf obo:GO_0032298, obo:GO_1903465, obo:GO_1903466, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1902975 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1902975 ] ) ] . obo:GO_1903490 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2014-09-25T09:00:35Z" ; oboInOwl:hasExactSynonym "positive regulation of cytokinesis after mitosis", "up regulation of cytokinesis after mitosis", "up regulation of mitotic cytokinesis", "up-regulation of cytokinesis after mitosis", "up-regulation of mitotic cytokinesis", "upregulation of cytokinesis after mitosis", "upregulation of mitotic cytokinesis" ; oboInOwl:hasNarrowSynonym "activation of cytokinesis after mitosis", "activation of mitotic cytokinesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903490" ; a owl:Class ; rdfs:label "positive regulation of mitotic cytokinesis" ; rdfs:subClassOf obo:GO_0032467, obo:GO_1902412, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000281 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000281 ] ) ] . obo:GO_1903504 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2014-10-01T13:52:57Z" ; oboInOwl:hasExactSynonym "regulation of mitotic cell cycle spindle checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903504" ; oboInOwl:inSubset go:gocheck_do_not_manually_annotate ; a owl:Class ; rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to specify the type of spindle checkpoint (assembly, orientation or Dma1-dependent)." ; rdfs:label "regulation of mitotic spindle checkpoint" ; rdfs:subClassOf obo:GO_0007346, obo:GO_0090231, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071174 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071174 ] ) ] . obo:GO_1903530 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of secretion by cell." ; oboInOwl:created_by "pm" ; oboInOwl:creation_date "2014-10-08T13:24:59Z" ; oboInOwl:hasExactSynonym "regulation of cellular secretion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903530" ; a owl:Class ; rdfs:label "regulation of secretion by cell" ; rdfs:subClassOf obo:GO_0050794, obo:GO_0051046, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032940 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032940 ] ) ] . obo:GO_1903531 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell." ; oboInOwl:created_by "pm" ; oboInOwl:creation_date "2014-10-08T13:25:08Z" ; oboInOwl:hasExactSynonym "down regulation of cellular secretion", "down regulation of secretion by cell", "down-regulation of cellular secretion", "down-regulation of secretion by cell", "downregulation of cellular secretion", "downregulation of secretion by cell", "negative regulation of cellular secretion" ; oboInOwl:hasNarrowSynonym "inhibition of cellular secretion", "inhibition of secretion by cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903531" ; a owl:Class ; rdfs:label "negative regulation of secretion by cell" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0051048, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032940 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0032940 ] ) ] . obo:GO_1903532 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of secretion by cell." ; oboInOwl:created_by "pm" ; oboInOwl:creation_date "2014-10-08T13:25:17Z" ; oboInOwl:hasExactSynonym "positive regulation of cellular secretion", "up regulation of cellular secretion", "up regulation of secretion by cell", "up-regulation of cellular secretion", "up-regulation of secretion by cell", "upregulation of cellular secretion", "upregulation of secretion by cell" ; oboInOwl:hasNarrowSynonym "activation of cellular secretion", "activation of secretion by cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903532" ; a owl:Class ; rdfs:label "positive regulation of secretion by cell" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0051047, obo:GO_1903530, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032940 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0032940 ] ) ] . obo:GO_1903537 obo:IAO_0000115 "Any meiotic cell cycle process that is involved in oocyte maturation." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2014-10-09T10:46:14Z" ; oboInOwl:hasBroadSynonym "meiosis involved in oocyte maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903537" ; a owl:Class ; rdfs:label "meiotic cell cycle process involved in oocyte maturation" ; rdfs:subClassOf obo:GO_0022412, obo:GO_1903046, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001556 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_1903046 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0001556 ] ) ] . obo:GO_1903538 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2014-10-09T10:52:38Z" ; oboInOwl:hasBroadSynonym "regulation of meiosis involved in oocyte maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903538" ; a owl:Class ; rdfs:label "regulation of meiotic cell cycle process involved in oocyte maturation" ; rdfs:subClassOf obo:GO_0010564, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1903537 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1903537 ] ) ] . obo:GO_1903573 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2014-10-27T16:15:30Z" ; oboInOwl:hasExactSynonym "down regulation of ER stress response", "down regulation of cellular response to endoplasmic reticulum stress", "down regulation of response to ER stress", "down regulation of response to endoplasmic reticulum stress", "down-regulation of ER stress response", "down-regulation of cellular response to endoplasmic reticulum stress", "down-regulation of response to ER stress", "down-regulation of response to endoplasmic reticulum stress", "downregulation of ER stress response", "downregulation of cellular response to endoplasmic reticulum stress", "downregulation of response to ER stress", "downregulation of response to endoplasmic reticulum stress", "negative regulation of ER stress response", "negative regulation of cellular response to endoplasmic reticulum stress", "negative regulation of response to ER stress" ; oboInOwl:hasNarrowSynonym "inhibition of ER stress response", "inhibition of cellular response to endoplasmic reticulum stress", "inhibition of response to ER stress", "inhibition of response to endoplasmic reticulum stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903573" ; a owl:Class ; rdfs:label "negative regulation of response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0048523, obo:GO_0048585, obo:GO_1905897, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034976 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0034976 ] ) ] . obo:GO_1903599 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitochondrion degradation by autophagy." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2014-11-10T14:25:53Z" ; oboInOwl:hasBroadSynonym "positive regulation of mitochondrial degradation", "up regulation of mitochondrion degradation", "up-regulation of mitochondrion degradation", "upregulation of mitochondrion degradation" ; oboInOwl:hasExactSynonym "up regulation of mitophagy", "up-regulation of mitophagy", "upregulation of mitophagy" ; oboInOwl:hasNarrowSynonym "activation of mitophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of mitochondrion degradation" ; oboInOwl:id "GO:1903599" ; a owl:Class ; rdfs:comment "An example of this AMBRA1 - human (Q9C0C7) in PMID:21753002 inferred from direct assay" ; rdfs:label "positive regulation of autophagy of mitochondrion" ; rdfs:subClassOf obo:GO_0010508, obo:GO_0010822, obo:GO_1903146, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000422 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000422 ] ) ] . obo:GO_1903649 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cytoplasmic transport." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-11-24T13:38:17Z" ; oboInOwl:hasNarrowSynonym "regulation of cytoplasmic streaming" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903649" ; a owl:Class ; rdfs:label "regulation of cytoplasmic transport" ; rdfs:subClassOf obo:GO_0032386, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016482 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016482 ] ) ] . obo:GO_1903650 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-11-24T13:38:26Z" ; oboInOwl:hasExactSynonym "down regulation of cytoplasmic transport", "down-regulation of cytoplasmic transport", "downregulation of cytoplasmic transport" ; oboInOwl:hasNarrowSynonym "down regulation of cytoplasmic streaming", "down-regulation of cytoplasmic streaming", "downregulation of cytoplasmic streaming", "inhibition of cytoplasmic streaming", "inhibition of cytoplasmic transport", "negative regulation of cytoplasmic streaming" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903650" ; a owl:Class ; rdfs:label "negative regulation of cytoplasmic transport" ; rdfs:subClassOf obo:GO_0032387, obo:GO_1903649, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016482 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016482 ] ) ] . obo:GO_1903651 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cytoplasmic transport." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2014-11-24T13:38:34Z" ; oboInOwl:hasExactSynonym "up regulation of cytoplasmic transport", "up-regulation of cytoplasmic transport", "upregulation of cytoplasmic transport" ; oboInOwl:hasNarrowSynonym "activation of cytoplasmic streaming", "activation of cytoplasmic transport", "positive regulation of cytoplasmic streaming", "up regulation of cytoplasmic streaming", "up-regulation of cytoplasmic streaming", "upregulation of cytoplasmic streaming" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903651" ; a owl:Class ; rdfs:label "positive regulation of cytoplasmic transport" ; rdfs:subClassOf obo:GO_0032388, obo:GO_1903649, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016482 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016482 ] ) ] . obo:GO_1903729 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of plasma membrane organization." ; oboInOwl:created_by "al" ; oboInOwl:creation_date "2014-12-10T18:59:44Z" ; oboInOwl:hasExactSynonym "regulation of plasma membrane organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of plasma membrane organization and biogenesis" ; oboInOwl:id "GO:1903729" ; a owl:Class ; rdfs:label "regulation of plasma membrane organization" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007009 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007009 ] ) ] . obo:GO_1903742 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-12-12T16:28:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903742" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of anterograde synaptic vesicle transport" ; rdfs:subClassOf obo:GO_1901608, obo:GO_1902803, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048490 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048490 ] ) ] . obo:GO_1903743 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-12-12T16:28:37Z" ; oboInOwl:hasExactSynonym "down regulation of anterograde synaptic vesicle transport", "down-regulation of anterograde synaptic vesicle transport", "downregulation of anterograde synaptic vesicle transport" ; oboInOwl:hasNarrowSynonym "inhibition of anterograde synaptic vesicle transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903743" ; a owl:Class ; rdfs:label "negative regulation of anterograde synaptic vesicle transport" ; rdfs:subClassOf obo:GO_1901609, obo:GO_1902804, obo:GO_1903742, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048490 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048490 ] ) ] . obo:GO_1903744 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-12-12T16:28:46Z" ; oboInOwl:hasExactSynonym "up regulation of anterograde synaptic vesicle transport", "up-regulation of anterograde synaptic vesicle transport", "upregulation of anterograde synaptic vesicle transport" ; oboInOwl:hasNarrowSynonym "activation of anterograde synaptic vesicle transport" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903744" ; a owl:Class ; rdfs:label "positive regulation of anterograde synaptic vesicle transport" ; rdfs:subClassOf obo:GO_1901610, obo:GO_1902805, obo:GO_1903742, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048490 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048490 ] ) ] . obo:GO_1903745 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of nematode pharyngeal pumping." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-12-12T17:10:59Z" ; oboInOwl:hasExactSynonym "down regulation of pharyngeal pumping", "down-regulation of pharyngeal pumping", "downregulation of pharyngeal pumping" ; oboInOwl:hasNarrowSynonym "inhibition of pharyngeal pumping" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of pumping behavior", "down-regulation of pumping behavior", "downregulation of pumping behavior", "inhibition of pumping behavior", "negative regulation of pumping behavior" ; oboInOwl:id "GO:1903745" ; a owl:Class ; rdfs:label "negative regulation of nematode pharyngeal pumping" ; rdfs:subClassOf obo:GO_0043051, obo:GO_1903999, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043050 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043050 ] ) ] . obo:GO_1903746 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of nematode pharyngeal pumping." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2014-12-12T17:11:09Z" ; oboInOwl:hasExactSynonym "up regulation of pharyngeal pumping", "up-regulation of pharyngeal pumping", "upregulation of pharyngeal pumping" ; oboInOwl:hasNarrowSynonym "activation of pharyngeal pumping" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of pumping behavior", "positive regulation of pumping behavior", "up regulation of pumping behavior", "up-regulation of pumping behavior", "upregulation of pumping behavior" ; oboInOwl:id "GO:1903746" ; a owl:Class ; rdfs:label "positive regulation of nematode pharyngeal pumping" ; rdfs:subClassOf obo:GO_0043051, obo:GO_1904000, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043050 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043050 ] ) ] . obo:GO_1903828 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2015-01-20T14:32:24Z" ; oboInOwl:hasExactSynonym "down regulation of cellular protein localisation", "down regulation of cellular protein localization", "down-regulation of cellular protein localisation", "down-regulation of cellular protein localization", "downregulation of cellular protein localisation", "downregulation of cellular protein localization", "negative regulation of cellular protein localisation", "negative regulation of cellular protein localization" ; oboInOwl:hasNarrowSynonym "inhibition of cellular protein localisation", "inhibition of cellular protein localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903828" ; a owl:Class ; rdfs:label "negative regulation of protein localization" ; rdfs:subClassOf obo:GO_0032880, obo:GO_0048523, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008104 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008104 ] ) ] . obo:GO_1903829 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a protein localization." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2015-01-20T14:32:33Z" ; oboInOwl:hasExactSynonym "positive regulation of cellular protein localisation", "positive regulation of cellular protein localization", "up regulation of cellular protein localisation", "up regulation of cellular protein localization", "up-regulation of cellular protein localisation", "up-regulation of cellular protein localization", "upregulation of cellular protein localisation", "upregulation of cellular protein localization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903829" ; a owl:Class ; rdfs:label "positive regulation of protein localization" ; rdfs:subClassOf obo:GO_0032880, obo:GO_0048522, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008104 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008104 ] ) ] . obo:GO_1903998 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of eating behavior." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2015-03-05T20:40:22Z" ; oboInOwl:hasExactSynonym "regulation of eating behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903998" ; a owl:Class ; rdfs:label "regulation of eating behavior" ; rdfs:subClassOf obo:GO_0060259, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042755 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042755 ] ) ] . obo:GO_1903999 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2015-03-05T20:40:28Z" ; oboInOwl:hasExactSynonym "down regulation of eating behavior", "down regulation of eating behaviour", "down-regulation of eating behavior", "down-regulation of eating behaviour", "downregulation of eating behavior", "downregulation of eating behaviour", "negative regulation of eating behaviour" ; oboInOwl:hasNarrowSynonym "inhibition of eating behavior", "inhibition of eating behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1903999" ; a owl:Class ; rdfs:label "negative regulation of eating behavior" ; rdfs:subClassOf obo:GO_1903998, obo:GO_2000252, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042755 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042755 ] ) ] . obo:GO_1904000 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of eating behavior." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2015-03-05T20:40:35Z" ; oboInOwl:hasExactSynonym "positive regulation of eating behaviour", "up regulation of eating behavior", "up regulation of eating behaviour", "up-regulation of eating behavior", "up-regulation of eating behaviour", "upregulation of eating behavior", "upregulation of eating behaviour" ; oboInOwl:hasNarrowSynonym "activation of eating behavior", "activation of eating behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904000" ; a owl:Class ; rdfs:label "positive regulation of eating behavior" ; rdfs:subClassOf obo:GO_1903998, obo:GO_2000253, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042755 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042755 ] ) ] . obo:GO_1904092 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of autophagic cell death." ; oboInOwl:created_by "bhm" ; oboInOwl:creation_date "2015-03-26T16:41:32Z" ; oboInOwl:hasBroadSynonym "regulation of autophagic death", "regulation of programmed cell death by autophagy" ; oboInOwl:hasExactSynonym "regulation of programmed cell death by macroautophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of type II programmed cell death" ; oboInOwl:id "GO:1904092" ; a owl:Class ; rdfs:label "regulation of autophagic cell death" ; rdfs:subClassOf obo:GO_0043067, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048102 ] ) ] . obo:GO_1904093 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death." ; oboInOwl:created_by "bhm" ; oboInOwl:creation_date "2015-03-26T16:41:39Z" ; oboInOwl:hasExactSynonym "down regulation of autophagic cell death", "down regulation of programmed cell death by macroautophagy", "down-regulation of autophagic cell death", "down-regulation of programmed cell death by macroautophagy", "downregulation of autophagic cell death", "downregulation of programmed cell death by macroautophagy", "negative regulation of programmed cell death by macroautophagy" ; oboInOwl:hasNarrowSynonym "inhibition of autophagic cell death", "inhibition of programmed cell death by macroautophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of type II programmed cell death", "down-regulation of type II programmed cell death", "downregulation of type II programmed cell death", "inhibition of type II programmed cell death", "negative regulation of type II programmed cell death" ; oboInOwl:id "GO:1904093" ; a owl:Class ; rdfs:label "negative regulation of autophagic cell death" ; rdfs:subClassOf obo:GO_0043069, obo:GO_1904092, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048102 ] ) ] . obo:GO_1904094 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of autophagic cell death." ; oboInOwl:created_by "bhm" ; oboInOwl:creation_date "2015-03-26T16:41:45Z" ; oboInOwl:hasExactSynonym "positive regulation of programmed cell death by macroautophagy", "up regulation of autophagic cell death", "up regulation of programmed cell death by macroautophagy", "up-regulation of autophagic cell death", "up-regulation of programmed cell death by macroautophagy", "upregulation of autophagic cell death", "upregulation of programmed cell death by macroautophagy" ; oboInOwl:hasNarrowSynonym "activation of autophagic cell death", "activation of programmed cell death by macroautophagy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of type II programmed cell death", "positive regulation of type II programmed cell death", "up regulation of type II programmed cell death", "up-regulation of type II programmed cell death", "upregulation of type II programmed cell death" ; oboInOwl:id "GO:1904094" ; a owl:Class ; rdfs:label "positive regulation of autophagic cell death" ; rdfs:subClassOf obo:GO_0043068, obo:GO_1904092, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048102 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048102 ] ) ] . obo:GO_1904115 obo:IAO_0000115 "Any cytoplasm that is part of a axon." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2015-04-06T18:13:14Z" ; oboInOwl:hasExactSynonym "axoplasm" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:1904115" ; a owl:Class ; rdfs:label "axon cytoplasm" ; rdfs:subClassOf obo:GO_0120111, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030424 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030424 ] ) ] . obo:GO_1904145 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2015-04-14T15:59:22Z" ; oboInOwl:hasExactSynonym "down regulation of meiotic cell cycle process involved in oocyte maturation", "down-regulation of meiotic cell cycle process involved in oocyte maturation", "downregulation of meiotic cell cycle process involved in oocyte maturation" ; oboInOwl:hasNarrowSynonym "inhibition of meiotic cell cycle process involved in oocyte maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904145" ; a owl:Class ; rdfs:label "negative regulation of meiotic cell cycle process involved in oocyte maturation" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0051447, obo:GO_1900194, obo:GO_1903538, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1903537 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1903537 ] ) ] . obo:GO_1904146 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2015-04-14T15:59:28Z" ; oboInOwl:hasExactSynonym "up regulation of meiotic cell cycle process involved in oocyte maturation", "up-regulation of meiotic cell cycle process involved in oocyte maturation", "upregulation of meiotic cell cycle process involved in oocyte maturation" ; oboInOwl:hasNarrowSynonym "activation of meiotic cell cycle process involved in oocyte maturation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904146" ; a owl:Class ; rdfs:label "positive regulation of meiotic cell cycle process involved in oocyte maturation" ; rdfs:subClassOf obo:GO_0051446, obo:GO_0090068, obo:GO_1903538, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1903537 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1903537 ] ) ] . obo:GO_1904289 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2015-06-09T13:03:11Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904289" ; a owl:Class ; rdfs:label "regulation of mitotic DNA damage checkpoint" ; rdfs:subClassOf obo:GO_0007346, obo:GO_2000001, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0044773 ] ) ] . obo:GO_1904290 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2015-06-09T13:03:17Z" ; oboInOwl:hasExactSynonym "down regulation of mitotic DNA damage checkpoint", "down-regulation of mitotic DNA damage checkpoint", "downregulation of mitotic DNA damage checkpoint" ; oboInOwl:hasNarrowSynonym "inhibition of mitotic DNA damage checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904290" ; a owl:Class ; rdfs:label "negative regulation of mitotic DNA damage checkpoint" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0045931, obo:GO_1904289, obo:GO_2000002, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0044773 ] ) ] . obo:GO_1904291 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2015-06-09T13:03:23Z" ; oboInOwl:hasExactSynonym "up regulation of mitotic DNA damage checkpoint", "up-regulation of mitotic DNA damage checkpoint", "upregulation of mitotic DNA damage checkpoint" ; oboInOwl:hasNarrowSynonym "activation of mitotic DNA damage checkpoint" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904291" ; a owl:Class ; rdfs:label "positive regulation of mitotic DNA damage checkpoint" ; rdfs:subClassOf obo:GO_0090068, obo:GO_1904289, obo:GO_2000003, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044773 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0044773 ] ) ] . obo:GO_1904350 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2015-06-12T09:10:36Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of vacuolar protein breakdown", "regulation of vacuolar protein catabolic process", "regulation of vacuolar protein catabolism", "regulation of vacuolar protein degradation" ; oboInOwl:id "GO:1904350" ; a owl:Class ; rdfs:label "regulation of protein catabolic process in the vacuole" ; rdfs:subClassOf obo:GO_0042176, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007039 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007039 ] ) ] . obo:GO_1904351 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2015-06-12T09:10:42Z" ; oboInOwl:hasExactSynonym "down regulation of protein catabolic process in the vacuole", "down-regulation of protein catabolic process in the vacuole", "downregulation of protein catabolic process in the vacuole" ; oboInOwl:hasNarrowSynonym "inhibition of protein catabolic process in the vacuole" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of vacuolar protein breakdown", "down regulation of vacuolar protein catabolic process", "down regulation of vacuolar protein catabolism", "down regulation of vacuolar protein degradation", "down-regulation of vacuolar protein breakdown", "down-regulation of vacuolar protein catabolic process", "down-regulation of vacuolar protein catabolism", "down-regulation of vacuolar protein degradation", "downregulation of vacuolar protein breakdown", "downregulation of vacuolar protein catabolic process", "downregulation of vacuolar protein catabolism", "downregulation of vacuolar protein degradation", "inhibition of vacuolar protein breakdown", "inhibition of vacuolar protein catabolic process", "inhibition of vacuolar protein catabolism", "inhibition of vacuolar protein degradation", "negative regulation of vacuolar protein breakdown", "negative regulation of vacuolar protein catabolic process", "negative regulation of vacuolar protein catabolism", "negative regulation of vacuolar protein degradation" ; oboInOwl:id "GO:1904351" ; a owl:Class ; rdfs:label "negative regulation of protein catabolic process in the vacuole" ; rdfs:subClassOf obo:GO_0042177, obo:GO_1904350, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007039 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007039 ] ) ] . obo:GO_1904352 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2015-06-12T09:10:49Z" ; oboInOwl:hasExactSynonym "up regulation of protein catabolic process in the vacuole", "up-regulation of protein catabolic process in the vacuole", "upregulation of protein catabolic process in the vacuole" ; oboInOwl:hasNarrowSynonym "activation of protein catabolic process in the vacuole" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of vacuolar protein breakdown", "activation of vacuolar protein catabolic process", "activation of vacuolar protein catabolism", "activation of vacuolar protein degradation", "positive regulation of vacuolar protein breakdown", "positive regulation of vacuolar protein catabolic process", "positive regulation of vacuolar protein catabolism", "positive regulation of vacuolar protein degradation", "up regulation of vacuolar protein breakdown", "up regulation of vacuolar protein catabolic process", "up regulation of vacuolar protein catabolism", "up regulation of vacuolar protein degradation", "up-regulation of vacuolar protein breakdown", "up-regulation of vacuolar protein catabolic process", "up-regulation of vacuolar protein catabolism", "up-regulation of vacuolar protein degradation", "upregulation of vacuolar protein breakdown", "upregulation of vacuolar protein catabolic process", "upregulation of vacuolar protein catabolism", "upregulation of vacuolar protein degradation" ; oboInOwl:id "GO:1904352" ; a owl:Class ; rdfs:label "positive regulation of protein catabolic process in the vacuole" ; rdfs:subClassOf obo:GO_0045732, obo:GO_1904350, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007039 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007039 ] ) ] . obo:GO_1904356 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening." ; oboInOwl:created_by "nc" ; oboInOwl:creation_date "2015-06-12T16:53:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904356" ; a owl:Class ; rdfs:label "regulation of telomere maintenance via telomere lengthening" ; rdfs:subClassOf obo:GO_0032204, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010833 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010833 ] ) ] . obo:GO_1904357 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening." ; oboInOwl:created_by "nc" ; oboInOwl:creation_date "2015-06-12T16:53:22Z" ; oboInOwl:hasExactSynonym "down regulation of telomere maintenance via telomere lengthening", "down-regulation of telomere maintenance via telomere lengthening", "downregulation of telomere maintenance via telomere lengthening" ; oboInOwl:hasNarrowSynonym "inhibition of telomere maintenance via telomere lengthening" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904357" ; a owl:Class ; rdfs:label "negative regulation of telomere maintenance via telomere lengthening" ; rdfs:subClassOf obo:GO_0032205, obo:GO_1904356, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010833 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010833 ] ) ] . obo:GO_1904358 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening." ; oboInOwl:created_by "nc" ; oboInOwl:creation_date "2015-06-12T16:53:28Z" ; oboInOwl:hasExactSynonym "up regulation of telomere maintenance via telomere lengthening", "up-regulation of telomere maintenance via telomere lengthening", "upregulation of telomere maintenance via telomere lengthening" ; oboInOwl:hasNarrowSynonym "activation of telomere maintenance via telomere lengthening" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904358" ; a owl:Class ; rdfs:label "positive regulation of telomere maintenance via telomere lengthening" ; rdfs:subClassOf obo:GO_0032206, obo:GO_1904356, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010833 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010833 ] ) ] . obo:GO_1904409 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of secretory granule organization." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2015-06-25T19:40:42Z" ; oboInOwl:hasExactSynonym "regulation of secretory granule organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of secretory granule organization and biogenesis" ; oboInOwl:id "GO:1904409" ; a owl:Class ; rdfs:label "regulation of secretory granule organization" ; rdfs:subClassOf obo:GO_0033043, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033363 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0033363 ] ) ] . obo:GO_1904410 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2015-06-25T19:40:49Z" ; oboInOwl:hasExactSynonym "down regulation of secretory granule organisation", "down regulation of secretory granule organization", "down-regulation of secretory granule organisation", "down-regulation of secretory granule organization", "downregulation of secretory granule organisation", "downregulation of secretory granule organization", "negative regulation of secretory granule organisation" ; oboInOwl:hasNarrowSynonym "inhibition of secretory granule organisation", "inhibition of secretory granule organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of secretory granule organization and biogenesis", "down-regulation of secretory granule organization and biogenesis", "downregulation of secretory granule organization and biogenesis", "inhibition of secretory granule organization and biogenesis", "negative regulation of secretory granule organization and biogenesis" ; oboInOwl:id "GO:1904410" ; a owl:Class ; rdfs:label "negative regulation of secretory granule organization" ; rdfs:subClassOf obo:GO_0010639, obo:GO_1904409, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0033363 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0033363 ] ) ] . obo:GO_1904411 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of secretory granule organization." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2015-06-25T19:40:55Z" ; oboInOwl:hasExactSynonym "positive regulation of secretory granule organisation", "up regulation of secretory granule organisation", "up regulation of secretory granule organization", "up-regulation of secretory granule organisation", "up-regulation of secretory granule organization", "upregulation of secretory granule organisation", "upregulation of secretory granule organization" ; oboInOwl:hasNarrowSynonym "activation of secretory granule organisation", "activation of secretory granule organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of secretory granule organization and biogenesis", "positive regulation of secretory granule organization and biogenesis", "up regulation of secretory granule organization and biogenesis", "up-regulation of secretory granule organization and biogenesis", "upregulation of secretory granule organization and biogenesis" ; oboInOwl:id "GO:1904411" ; a owl:Class ; rdfs:label "positive regulation of secretory granule organization" ; rdfs:subClassOf obo:GO_0010638, obo:GO_1904409, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0033363 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0033363 ] ) ] . obo:GO_1904512 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2015-07-28T12:59:17Z" ; oboInOwl:hasExactSynonym "regulation of premeiotic DNA replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of initiation of meiotic DNA synthesis", "regulation of initiation of premeiotic DNA synthesis", "regulation of meiotic DNA replication initiation" ; oboInOwl:id "GO:1904512" ; a owl:Class ; rdfs:label "regulation of initiation of premeiotic DNA replication" ; rdfs:subClassOf obo:GO_0030174, obo:GO_0033262, obo:GO_0051445, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1902974 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1902974 ] ) ] . obo:GO_1904513 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2015-07-28T12:59:23Z" ; oboInOwl:hasExactSynonym "down regulation of initiation of premeiotic DNA replication", "down regulation of premeiotic DNA replication initiation", "down-regulation of initiation of premeiotic DNA replication", "down-regulation of premeiotic DNA replication initiation", "downregulation of initiation of premeiotic DNA replication", "downregulation of premeiotic DNA replication initiation", "negative regulation of premeiotic DNA replication initiation" ; oboInOwl:hasNarrowSynonym "inhibition of initiation of premeiotic DNA replication", "inhibition of premeiotic DNA replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of initiation of meiotic DNA synthesis", "down regulation of initiation of premeiotic DNA synthesis", "down regulation of meiotic DNA replication initiation", "down-regulation of initiation of meiotic DNA synthesis", "down-regulation of initiation of premeiotic DNA synthesis", "down-regulation of meiotic DNA replication initiation", "downregulation of initiation of meiotic DNA synthesis", "downregulation of initiation of premeiotic DNA synthesis", "downregulation of meiotic DNA replication initiation", "inhibition of initiation of meiotic DNA synthesis", "inhibition of initiation of premeiotic DNA synthesis", "inhibition of meiotic DNA replication initiation", "negative regulation of initiation of meiotic DNA synthesis", "negative regulation of initiation of premeiotic DNA synthesis", "negative regulation of meiotic DNA replication initiation" ; oboInOwl:id "GO:1904513" ; a owl:Class ; rdfs:label "negative regulation of initiation of premeiotic DNA replication" ; rdfs:subClassOf obo:GO_0032297, obo:GO_0051447, obo:GO_1902576, obo:GO_1904512, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1902974 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1902974 ] ) ] . obo:GO_1904514 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2015-07-28T12:59:29Z" ; oboInOwl:hasExactSynonym "positive regulation of premeiotic DNA replication initiation", "up regulation of initiation of premeiotic DNA replication", "up regulation of premeiotic DNA replication initiation", "up-regulation of initiation of premeiotic DNA replication", "up-regulation of premeiotic DNA replication initiation", "upregulation of initiation of premeiotic DNA replication", "upregulation of premeiotic DNA replication initiation" ; oboInOwl:hasNarrowSynonym "activation of initiation of premeiotic DNA replication", "activation of premeiotic DNA replication initiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of initiation of meiotic DNA synthesis", "activation of initiation of premeiotic DNA synthesis", "activation of meiotic DNA replication initiation", "positive regulation of initiation of meiotic DNA synthesis", "positive regulation of initiation of premeiotic DNA synthesis", "positive regulation of meiotic DNA replication initiation", "up regulation of initiation of meiotic DNA synthesis", "up regulation of initiation of premeiotic DNA synthesis", "up regulation of meiotic DNA replication initiation", "up-regulation of initiation of meiotic DNA synthesis", "up-regulation of initiation of premeiotic DNA synthesis", "up-regulation of meiotic DNA replication initiation", "upregulation of initiation of meiotic DNA synthesis", "upregulation of initiation of premeiotic DNA synthesis", "upregulation of meiotic DNA replication initiation" ; oboInOwl:id "GO:1904514" ; a owl:Class ; rdfs:label "positive regulation of initiation of premeiotic DNA replication" ; rdfs:subClassOf obo:GO_0010571, obo:GO_0032298, obo:GO_1904512, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1902974 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1902974 ] ) ] . obo:GO_1904576 obo:IAO_0000115 "OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/17227"^^xsd:anyURI ; oboInOwl:consider "GO:0034976" ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2015-08-19T18:01:52Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904576" ; a owl:Class ; rdfs:comment "This term was obsoleted because it represents an experimental condition to cause endoplasmic reticulum stress." ; rdfs:label "obsolete response to tunicamycin" ; owl:deprecated true . obo:GO_1904746 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development." ; oboInOwl:created_by "es" ; oboInOwl:creation_date "2015-10-19T14:12:27Z" ; oboInOwl:hasExactSynonym "down regulation of apoptotic cell death involved in anatomical structure development", "down regulation of apoptotic cell death involved in development of an anatomical structure", "down regulation of apoptotic process involved in anatomical structure development", "down regulation of apoptotic process involved in development", "down regulation of apoptotic process involved in development of an anatomical structure", "down regulation of apoptotic programmed cell death involved in anatomical structure development", "down regulation of apoptotic programmed cell death involved in development of an anatomical structure", "down regulation of programmed cell death by apoptosis involved in anatomical structure development", "down regulation of programmed cell death by apoptosis involved in development of an anatomical structure", "down-regulation of apoptotic cell death involved in anatomical structure development", "down-regulation of apoptotic cell death involved in development of an anatomical structure", "down-regulation of apoptotic process involved in anatomical structure development", "down-regulation of apoptotic process involved in development", "down-regulation of apoptotic process involved in development of an anatomical structure", "down-regulation of apoptotic programmed cell death involved in anatomical structure development", "down-regulation of apoptotic programmed cell death involved in development of an anatomical structure", "down-regulation of programmed cell death by apoptosis involved in anatomical structure development", "down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure", "downregulation of apoptotic cell death involved in anatomical structure development", "downregulation of apoptotic cell death involved in development of an anatomical structure", "downregulation of apoptotic process involved in anatomical structure development", "downregulation of apoptotic process involved in development", "downregulation of apoptotic process involved in development of an anatomical structure", "downregulation of apoptotic programmed cell death involved in anatomical structure development", "downregulation of apoptotic programmed cell death involved in development of an anatomical structure", "downregulation of programmed cell death by apoptosis involved in anatomical structure development", "downregulation of programmed cell death by apoptosis involved in development of an anatomical structure", "negative regulation of apoptotic cell death involved in anatomical structure development", "negative regulation of apoptotic cell death involved in development of an anatomical structure", "negative regulation of apoptotic process involved in anatomical structure development", "negative regulation of apoptotic process involved in development of an anatomical structure", "negative regulation of apoptotic programmed cell death involved in anatomical structure development", "negative regulation of apoptotic programmed cell death involved in development of an anatomical structure", "negative regulation of programmed cell death by apoptosis involved in anatomical structure development", "negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure" ; oboInOwl:hasNarrowSynonym "down regulation of activation of apoptosis involved in anatomical structure development", "down regulation of activation of apoptosis involved in development of an anatomical structure", "down regulation of apoptosis involved in anatomical structure development", "down regulation of apoptosis involved in development of an anatomical structure", "down regulation of apoptosis signaling involved in anatomical structure development", "down regulation of apoptosis signaling involved in development of an anatomical structure", "down regulation of apoptotic program involved in anatomical structure development", "down regulation of apoptotic program involved in development of an anatomical structure", "down regulation of type I programmed cell death involved in anatomical structure development", "down regulation of type I programmed cell death involved in development of an anatomical structure", "down-regulation of activation of apoptosis involved in anatomical structure development", "down-regulation of activation of apoptosis involved in development of an anatomical structure", "down-regulation of apoptosis involved in anatomical structure development", "down-regulation of apoptosis involved in development of an anatomical structure", "down-regulation of apoptosis signaling involved in anatomical structure development", "down-regulation of apoptosis signaling involved in development of an anatomical structure", "down-regulation of apoptotic program involved in anatomical structure development", "down-regulation of apoptotic program involved in development of an anatomical structure", "down-regulation of type I programmed cell death involved in anatomical structure development", "down-regulation of type I programmed cell death involved in development of an anatomical structure", "downregulation of activation of apoptosis involved in anatomical structure development", "downregulation of activation of apoptosis involved in development of an anatomical structure", "downregulation of apoptosis involved in anatomical structure development", "downregulation of apoptosis involved in development of an anatomical structure", "downregulation of apoptosis signaling involved in anatomical structure development", "downregulation of apoptosis signaling involved in development of an anatomical structure", "downregulation of apoptotic program involved in anatomical structure development", "downregulation of apoptotic program involved in development of an anatomical structure", "downregulation of type I programmed cell death involved in anatomical structure development", "downregulation of type I programmed cell death involved in development of an anatomical structure", "inhibition of activation of apoptosis involved in anatomical structure development", "inhibition of activation of apoptosis involved in development of an anatomical structure", "inhibition of apoptosis involved in anatomical structure development", "inhibition of apoptosis involved in development of an anatomical structure", "inhibition of apoptosis signaling involved in anatomical structure development", "inhibition of apoptosis signaling involved in development of an anatomical structure", "inhibition of apoptotic cell death involved in anatomical structure development", "inhibition of apoptotic cell death involved in development of an anatomical structure", "inhibition of apoptotic process involved in anatomical structure development", "inhibition of apoptotic process involved in development", "inhibition of apoptotic process involved in development of an anatomical structure", "inhibition of apoptotic program involved in anatomical structure development", "inhibition of apoptotic program involved in development of an anatomical structure", "inhibition of apoptotic programmed cell death involved in anatomical structure development", "inhibition of apoptotic programmed cell death involved in development of an anatomical structure", "inhibition of programmed cell death by apoptosis involved in anatomical structure development", "inhibition of programmed cell death by apoptosis involved in development of an anatomical structure", "inhibition of type I programmed cell death involved in anatomical structure development", "inhibition of type I programmed cell death involved in development of an anatomical structure", "negative regulation of activation of apoptosis involved in anatomical structure development", "negative regulation of activation of apoptosis involved in development of an anatomical structure", "negative regulation of apoptosis involved in anatomical structure development", "negative regulation of apoptosis involved in development of an anatomical structure", "negative regulation of apoptosis signaling involved in anatomical structure development", "negative regulation of apoptosis signaling involved in development of an anatomical structure", "negative regulation of apoptotic program involved in anatomical structure development", "negative regulation of apoptotic program involved in development of an anatomical structure", "negative regulation of type I programmed cell death involved in anatomical structure development", "negative regulation of type I programmed cell death involved in development of an anatomical structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of apoptosis activator activity involved in anatomical structure development", "down regulation of apoptosis activator activity involved in development of an anatomical structure", "down regulation of commitment to apoptosis involved in anatomical structure development", "down regulation of commitment to apoptosis involved in development of an anatomical structure", "down regulation of induction of apoptosis by p53 involved in anatomical structure development", "down regulation of induction of apoptosis by p53 involved in development of an anatomical structure", "down regulation of induction of apoptosis involved in anatomical structure development", "down regulation of induction of apoptosis involved in development of an anatomical structure", "down regulation of signaling (initiator) caspase activity involved in anatomical structure development", "down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure", "down-regulation of apoptosis activator activity involved in anatomical structure development", "down-regulation of apoptosis activator activity involved in development of an anatomical structure", "down-regulation of commitment to apoptosis involved in anatomical structure development", "down-regulation of commitment to apoptosis involved in development of an anatomical structure", "down-regulation of induction of apoptosis by p53 involved in anatomical structure development", "down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure", "down-regulation of induction of apoptosis involved in anatomical structure development", "down-regulation of induction of apoptosis involved in development of an anatomical structure", "down-regulation of signaling (initiator) caspase activity involved in anatomical structure development", "down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure", "downregulation of apoptosis activator activity involved in anatomical structure development", "downregulation of apoptosis activator activity involved in development of an anatomical structure", "downregulation of commitment to apoptosis involved in anatomical structure development", "downregulation of commitment to apoptosis involved in development of an anatomical structure", "downregulation of induction of apoptosis by p53 involved in anatomical structure development", "downregulation of induction of apoptosis by p53 involved in development of an anatomical structure", "downregulation of induction of apoptosis involved in anatomical structure development", "downregulation of induction of apoptosis involved in development of an anatomical structure", "downregulation of signaling (initiator) caspase activity involved in anatomical structure development", "downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure", "inhibition of apoptosis activator activity involved in anatomical structure development", "inhibition of apoptosis activator activity involved in development of an anatomical structure", "inhibition of commitment to apoptosis involved in anatomical structure development", "inhibition of commitment to apoptosis involved in development of an anatomical structure", "inhibition of induction of apoptosis by p53 involved in anatomical structure development", "inhibition of induction of apoptosis by p53 involved in development of an anatomical structure", "inhibition of induction of apoptosis involved in anatomical structure development", "inhibition of induction of apoptosis involved in development of an anatomical structure", "inhibition of signaling (initiator) caspase activity involved in anatomical structure development", "inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure", "negative regulation of apoptosis activator activity involved in anatomical structure development", "negative regulation of apoptosis activator activity involved in development of an anatomical structure", "negative regulation of commitment to apoptosis involved in anatomical structure development", "negative regulation of commitment to apoptosis involved in development of an anatomical structure", "negative regulation of induction of apoptosis by p53 involved in anatomical structure development", "negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure", "negative regulation of induction of apoptosis involved in anatomical structure development", "negative regulation of induction of apoptosis involved in development of an anatomical structure", "negative regulation of signaling (initiator) caspase activity involved in anatomical structure development", "negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" ; oboInOwl:id "GO:1904746" ; a owl:Class ; rdfs:comment "U4PR86 in PMID:22801495 inferred from mutant phenotype" ; rdfs:label "negative regulation of apoptotic process involved in development" ; rdfs:subClassOf obo:GO_0043066, obo:GO_0051093, obo:GO_1904748, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1902742 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1902742 ] ) ] . obo:GO_1904747 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development." ; oboInOwl:created_by "es" ; oboInOwl:creation_date "2015-10-19T14:12:34Z" ; oboInOwl:hasExactSynonym "positive regulation of apoptotic cell death involved in anatomical structure development", "positive regulation of apoptotic cell death involved in development of an anatomical structure", "positive regulation of apoptotic process involved in anatomical structure development", "positive regulation of apoptotic process involved in development of an anatomical structure", "positive regulation of apoptotic programmed cell death involved in anatomical structure development", "positive regulation of apoptotic programmed cell death involved in development of an anatomical structure", "positive regulation of programmed cell death by apoptosis involved in anatomical structure development", "positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure", "up regulation of apoptotic cell death involved in anatomical structure development", "up regulation of apoptotic cell death involved in development of an anatomical structure", "up regulation of apoptotic process involved in anatomical structure development", "up regulation of apoptotic process involved in development", "up regulation of apoptotic process involved in development of an anatomical structure", "up regulation of apoptotic programmed cell death involved in anatomical structure development", "up regulation of apoptotic programmed cell death involved in development of an anatomical structure", "up regulation of programmed cell death by apoptosis involved in anatomical structure development", "up regulation of programmed cell death by apoptosis involved in development of an anatomical structure", "up-regulation of apoptotic cell death involved in anatomical structure development", "up-regulation of apoptotic cell death involved in development of an anatomical structure", "up-regulation of apoptotic process involved in anatomical structure development", "up-regulation of apoptotic process involved in development", "up-regulation of apoptotic process involved in development of an anatomical structure", "up-regulation of apoptotic programmed cell death involved in anatomical structure development", "up-regulation of apoptotic programmed cell death involved in development of an anatomical structure", "up-regulation of programmed cell death by apoptosis involved in anatomical structure development", "up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure", "upregulation of apoptotic cell death involved in anatomical structure development", "upregulation of apoptotic cell death involved in development of an anatomical structure", "upregulation of apoptotic process involved in anatomical structure development", "upregulation of apoptotic process involved in development", "upregulation of apoptotic process involved in development of an anatomical structure", "upregulation of apoptotic programmed cell death involved in anatomical structure development", "upregulation of apoptotic programmed cell death involved in development of an anatomical structure", "upregulation of programmed cell death by apoptosis involved in anatomical structure development", "upregulation of programmed cell death by apoptosis involved in development of an anatomical structure" ; oboInOwl:hasNarrowSynonym "activation of activation of apoptosis involved in anatomical structure development", "activation of activation of apoptosis involved in development of an anatomical structure", "activation of apoptosis involved in anatomical structure development", "activation of apoptosis involved in development of an anatomical structure", "activation of apoptosis signaling involved in anatomical structure development", "activation of apoptosis signaling involved in development of an anatomical structure", "activation of apoptotic cell death involved in anatomical structure development", "activation of apoptotic cell death involved in development of an anatomical structure", "activation of apoptotic process involved in anatomical structure development", "activation of apoptotic process involved in development", "activation of apoptotic process involved in development of an anatomical structure", "activation of apoptotic program involved in anatomical structure development", "activation of apoptotic program involved in development of an anatomical structure", "activation of apoptotic programmed cell death involved in anatomical structure development", "activation of apoptotic programmed cell death involved in development of an anatomical structure", "activation of programmed cell death by apoptosis involved in anatomical structure development", "activation of programmed cell death by apoptosis involved in development of an anatomical structure", "activation of type I programmed cell death involved in anatomical structure development", "activation of type I programmed cell death involved in development of an anatomical structure", "positive regulation of activation of apoptosis involved in anatomical structure development", "positive regulation of activation of apoptosis involved in development of an anatomical structure", "positive regulation of apoptosis involved in anatomical structure development", "positive regulation of apoptosis involved in development of an anatomical structure", "positive regulation of apoptosis signaling involved in anatomical structure development", "positive regulation of apoptosis signaling involved in development of an anatomical structure", "positive regulation of apoptotic program involved in anatomical structure development", "positive regulation of apoptotic program involved in development of an anatomical structure", "positive regulation of type I programmed cell death involved in anatomical structure development", "positive regulation of type I programmed cell death involved in development of an anatomical structure", "up regulation of activation of apoptosis involved in anatomical structure development", "up regulation of activation of apoptosis involved in development of an anatomical structure", "up regulation of apoptosis involved in anatomical structure development", "up regulation of apoptosis involved in development of an anatomical structure", "up regulation of apoptosis signaling involved in anatomical structure development", "up regulation of apoptosis signaling involved in development of an anatomical structure", "up regulation of apoptotic program involved in anatomical structure development", "up regulation of apoptotic program involved in development of an anatomical structure", "up regulation of type I programmed cell death involved in anatomical structure development", "up regulation of type I programmed cell death involved in development of an anatomical structure", "up-regulation of activation of apoptosis involved in anatomical structure development", "up-regulation of activation of apoptosis involved in development of an anatomical structure", "up-regulation of apoptosis involved in anatomical structure development", "up-regulation of apoptosis involved in development of an anatomical structure", "up-regulation of apoptosis signaling involved in anatomical structure development", "up-regulation of apoptosis signaling involved in development of an anatomical structure", "up-regulation of apoptotic program involved in anatomical structure development", "up-regulation of apoptotic program involved in development of an anatomical structure", "up-regulation of type I programmed cell death involved in anatomical structure development", "up-regulation of type I programmed cell death involved in development of an anatomical structure", "upregulation of activation of apoptosis involved in anatomical structure development", "upregulation of activation of apoptosis involved in development of an anatomical structure", "upregulation of apoptosis involved in anatomical structure development", "upregulation of apoptosis involved in development of an anatomical structure", "upregulation of apoptosis signaling involved in anatomical structure development", "upregulation of apoptosis signaling involved in development of an anatomical structure", "upregulation of apoptotic program involved in anatomical structure development", "upregulation of apoptotic program involved in development of an anatomical structure", "upregulation of type I programmed cell death involved in anatomical structure development", "upregulation of type I programmed cell death involved in development of an anatomical structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of apoptosis activator activity involved in anatomical structure development", "activation of apoptosis activator activity involved in development of an anatomical structure", "activation of commitment to apoptosis involved in anatomical structure development", "activation of commitment to apoptosis involved in development of an anatomical structure", "activation of induction of apoptosis by p53 involved in anatomical structure development", "activation of induction of apoptosis by p53 involved in development of an anatomical structure", "activation of induction of apoptosis involved in anatomical structure development", "activation of induction of apoptosis involved in development of an anatomical structure", "activation of signaling (initiator) caspase activity involved in anatomical structure development", "activation of signaling (initiator) caspase activity involved in development of an anatomical structure", "positive regulation of apoptosis activator activity involved in anatomical structure development", "positive regulation of apoptosis activator activity involved in development of an anatomical structure", "positive regulation of commitment to apoptosis involved in anatomical structure development", "positive regulation of commitment to apoptosis involved in development of an anatomical structure", "positive regulation of induction of apoptosis by p53 involved in anatomical structure development", "positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure", "positive regulation of induction of apoptosis involved in anatomical structure development", "positive regulation of induction of apoptosis involved in development of an anatomical structure", "positive regulation of signaling (initiator) caspase activity involved in anatomical structure development", "positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure", "up regulation of apoptosis activator activity involved in anatomical structure development", "up regulation of apoptosis activator activity involved in development of an anatomical structure", "up regulation of commitment to apoptosis involved in anatomical structure development", "up regulation of commitment to apoptosis involved in development of an anatomical structure", "up regulation of induction of apoptosis by p53 involved in anatomical structure development", "up regulation of induction of apoptosis by p53 involved in development of an anatomical structure", "up regulation of induction of apoptosis involved in anatomical structure development", "up regulation of induction of apoptosis involved in development of an anatomical structure", "up regulation of signaling (initiator) caspase activity involved in anatomical structure development", "up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure", "up-regulation of apoptosis activator activity involved in anatomical structure development", "up-regulation of apoptosis activator activity involved in development of an anatomical structure", "up-regulation of commitment to apoptosis involved in anatomical structure development", "up-regulation of commitment to apoptosis involved in development of an anatomical structure", "up-regulation of induction of apoptosis by p53 involved in anatomical structure development", "up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure", "up-regulation of induction of apoptosis involved in anatomical structure development", "up-regulation of induction of apoptosis involved in development of an anatomical structure", "up-regulation of signaling (initiator) caspase activity involved in anatomical structure development", "up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure", "upregulation of apoptosis activator activity involved in anatomical structure development", "upregulation of apoptosis activator activity involved in development of an anatomical structure", "upregulation of commitment to apoptosis involved in anatomical structure development", "upregulation of commitment to apoptosis involved in development of an anatomical structure", "upregulation of induction of apoptosis by p53 involved in anatomical structure development", "upregulation of induction of apoptosis by p53 involved in development of an anatomical structure", "upregulation of induction of apoptosis involved in anatomical structure development", "upregulation of induction of apoptosis involved in development of an anatomical structure", "upregulation of signaling (initiator) caspase activity involved in anatomical structure development", "upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure" ; oboInOwl:id "GO:1904747" ; a owl:Class ; rdfs:comment "U4PR86 in PMID:22801495 inferred from mutant phenotype" ; rdfs:label "positive regulation of apoptotic process involved in development" ; rdfs:subClassOf obo:GO_0043065, obo:GO_0051094, obo:GO_1904748, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1902742 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1902742 ] ) ] . obo:GO_1904748 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of apoptotic process involved in development." ; oboInOwl:created_by "es" ; oboInOwl:creation_date "2015-10-19T15:02:28Z" ; oboInOwl:hasExactSynonym "regulation of apoptotic cell death involved in anatomical structure development", "regulation of apoptotic cell death involved in development of an anatomical structure", "regulation of apoptotic process involved in anatomical structure development", "regulation of apoptotic process involved in development of an anatomical structure", "regulation of apoptotic programmed cell death involved in anatomical structure development", "regulation of apoptotic programmed cell death involved in development of an anatomical structure", "regulation of programmed cell death by apoptosis involved in anatomical structure development", "regulation of programmed cell death by apoptosis involved in development of an anatomical structure" ; oboInOwl:hasNarrowSynonym "regulation of activation of apoptosis involved in anatomical structure development", "regulation of activation of apoptosis involved in development of an anatomical structure", "regulation of apoptosis involved in anatomical structure development", "regulation of apoptosis involved in development of an anatomical structure", "regulation of apoptosis signaling involved in anatomical structure development", "regulation of apoptosis signaling involved in development of an anatomical structure", "regulation of apoptotic program involved in anatomical structure development", "regulation of apoptotic program involved in development of an anatomical structure", "regulation of type I programmed cell death involved in anatomical structure development", "regulation of type I programmed cell death involved in development of an anatomical structure" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of apoptosis activator activity involved in anatomical structure development", "regulation of apoptosis activator activity involved in development of an anatomical structure", "regulation of commitment to apoptosis involved in anatomical structure development", "regulation of commitment to apoptosis involved in development of an anatomical structure", "regulation of induction of apoptosis by p53 involved in anatomical structure development", "regulation of induction of apoptosis by p53 involved in development of an anatomical structure", "regulation of induction of apoptosis involved in anatomical structure development", "regulation of induction of apoptosis involved in development of an anatomical structure", "regulation of signaling (initiator) caspase activity involved in anatomical structure development", "regulation of signaling (initiator) caspase activity involved in development of an anatomical structure" ; oboInOwl:id "GO:1904748" ; a owl:Class ; rdfs:comment "Q10943 in PMID:22801495, inferred from mutant phenotype" ; rdfs:label "regulation of apoptotic process involved in development" ; rdfs:subClassOf obo:GO_0042981, obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1902742 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1902742 ] ) ] . obo:GO_1904803 obo:IAO_0000115 "Any regulation of translation that is involved in cellular response to UV." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2015-11-10T12:12:41Z" ; oboInOwl:hasExactSynonym "regulation of protein anabolism involved in cellular response to UV", "regulation of protein biosynthesis involved in cellular response to UV", "regulation of protein formation involved in cellular response to UV", "regulation of protein synthesis involved in cellular response to UV", "regulation of translation involved in cellular response to UV light stimulus", "regulation of translation involved in cellular response to UV radiation stimulus", "regulation of translation involved in cellular response to ultraviolet light stimulus", "regulation of translation involved in cellular response to ultraviolet radiation stimulus" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904803" ; a owl:Class ; rdfs:label "regulation of translation involved in cellular response to UV" ; rdfs:subClassOf obo:GO_0006417, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034644 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006417 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0034644 ] ) ] . obo:GO_1904860 obo:IAO_0000115 "Any DNA biosynthetic process that is involved in mitotic DNA replication." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2015-12-16T12:02:37Z" ; oboInOwl:hasExactSynonym "DNA anabolism involved in DNA replication involved in S phase involved in mitotic cell cycle", "DNA anabolism involved in DNA replication involved in S-phase involved in mitotic cell cycle", "DNA anabolism involved in mitotic DNA replication", "DNA anabolism involved in mitotic cell cycle DNA replication", "DNA anabolism involved in mitotic nuclear cell cycle DNA replication", "DNA biosynthesis involved in DNA replication involved in S phase involved in mitotic cell cycle", "DNA biosynthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle", "DNA biosynthesis involved in mitotic DNA replication", "DNA biosynthesis involved in mitotic cell cycle DNA replication", "DNA biosynthesis involved in mitotic nuclear cell cycle DNA replication", "DNA biosynthetic process involved in DNA replication involved in S phase involved in mitotic cell cycle", "DNA biosynthetic process involved in DNA replication involved in S-phase involved in mitotic cell cycle", "DNA biosynthetic process involved in mitotic DNA replication", "DNA biosynthetic process involved in mitotic cell cycle DNA replication", "DNA biosynthetic process involved in mitotic nuclear cell cycle DNA replication", "DNA formation involved in DNA replication involved in S phase involved in mitotic cell cycle", "DNA formation involved in DNA replication involved in S-phase involved in mitotic cell cycle", "DNA formation involved in mitotic DNA replication", "DNA formation involved in mitotic cell cycle DNA replication", "DNA formation involved in mitotic nuclear cell cycle DNA replication", "DNA synthesis involved in DNA replication involved in S phase involved in mitotic cell cycle", "DNA synthesis involved in DNA replication involved in S-phase involved in mitotic cell cycle", "DNA synthesis involved in mitotic cell cycle DNA replication", "DNA synthesis involved in mitotic nuclear cell cycle DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "DNA anabolism involved in DNA replication during S phase involved in mitotic cell cycle", "DNA anabolism involved in nuclear cell cycle DNA replication involved in mitotic cell cycle", "DNA biosynthesis involved in DNA replication during S phase involved in mitotic cell cycle", "DNA biosynthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle", "DNA biosynthetic process involved in DNA replication during S phase involved in mitotic cell cycle", "DNA biosynthetic process involved in nuclear cell cycle DNA replication involved in mitotic cell cycle", "DNA formation involved in DNA replication during S phase involved in mitotic cell cycle", "DNA formation involved in nuclear cell cycle DNA replication involved in mitotic cell cycle", "DNA synthesis involved in DNA replication during S phase involved in mitotic cell cycle", "DNA synthesis involved in nuclear cell cycle DNA replication involved in mitotic cell cycle" ; oboInOwl:id "GO:1904860" ; a owl:Class ; rdfs:label "DNA synthesis involved in mitotic DNA replication" ; rdfs:subClassOf obo:BFO_0000003, obo:GO_0090592, obo:GO_1903047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_1902969 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071897 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_1902969 ] ) ] . obo:GO_1904950 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization." ; oboInOwl:created_by "mec" ; oboInOwl:creation_date "2016-02-05T09:59:24Z" ; oboInOwl:hasExactSynonym "down regulation of establishment of protein localisation", "down regulation of establishment of protein localization", "down regulation of protein positioning", "down regulation of protein recruitment", "down-regulation of establishment of protein localisation", "down-regulation of establishment of protein localization", "down-regulation of protein positioning", "down-regulation of protein recruitment", "downregulation of establishment of protein localisation", "downregulation of establishment of protein localization", "downregulation of protein positioning", "downregulation of protein recruitment", "negative regulation of establishment of protein localisation", "negative regulation of protein positioning", "negative regulation of protein recruitment" ; oboInOwl:hasNarrowSynonym "inhibition of establishment of protein localisation", "inhibition of establishment of protein localization", "inhibition of protein positioning", "inhibition of protein recruitment" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904950" ; a owl:Class ; rdfs:label "negative regulation of establishment of protein localization" ; rdfs:subClassOf obo:GO_0070201, obo:GO_1903828, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045184 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0045184 ] ) ] . obo:GO_1904951 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of establishment of protein localization." ; oboInOwl:created_by "mec" ; oboInOwl:creation_date "2016-02-05T09:59:32Z" ; oboInOwl:hasExactSynonym "positive regulation of establishment of protein localisation", "positive regulation of protein positioning", "positive regulation of protein recruitment", "up regulation of establishment of protein localisation", "up regulation of establishment of protein localization", "up regulation of protein positioning", "up regulation of protein recruitment", "up-regulation of establishment of protein localisation", "up-regulation of establishment of protein localization", "up-regulation of protein positioning", "up-regulation of protein recruitment", "upregulation of establishment of protein localisation", "upregulation of establishment of protein localization", "upregulation of protein positioning", "upregulation of protein recruitment" ; oboInOwl:hasNarrowSynonym "activation of establishment of protein localisation", "activation of establishment of protein localization", "activation of protein positioning", "activation of protein recruitment" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1904951" ; a owl:Class ; rdfs:label "positive regulation of establishment of protein localization" ; rdfs:subClassOf obo:GO_0070201, obo:GO_1903829, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045184 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0045184 ] ) ] . obo:GO_1905082 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitochondrial translational elongation." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2016-03-25T17:37:03Z" ; oboInOwl:hasExactSynonym "regulation of mitochondrial translation elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905082" ; a owl:Class ; rdfs:label "regulation of mitochondrial translational elongation" ; rdfs:subClassOf obo:GO_0006448, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070125 ] ) ] . obo:GO_1905083 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2016-03-25T17:37:13Z" ; oboInOwl:hasExactSynonym "down regulation of mitochondrial translation elongation", "down regulation of mitochondrial translational elongation", "down-regulation of mitochondrial translation elongation", "down-regulation of mitochondrial translational elongation", "downregulation of mitochondrial translation elongation", "downregulation of mitochondrial translational elongation", "negative regulation of mitochondrial translation elongation" ; oboInOwl:hasNarrowSynonym "inhibition of mitochondrial translation elongation", "inhibition of mitochondrial translational elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905083" ; a owl:Class ; rdfs:label "negative regulation of mitochondrial translational elongation" ; rdfs:subClassOf obo:GO_0045900, obo:GO_0070130, obo:GO_1905082, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070125 ] ) ] . obo:GO_1905084 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation." ; oboInOwl:created_by "hjd" ; oboInOwl:creation_date "2016-03-25T17:37:22Z" ; oboInOwl:hasExactSynonym "positive regulation of mitochondrial translation elongation", "up regulation of mitochondrial translation elongation", "up regulation of mitochondrial translational elongation", "up-regulation of mitochondrial translation elongation", "up-regulation of mitochondrial translational elongation", "upregulation of mitochondrial translation elongation", "upregulation of mitochondrial translational elongation" ; oboInOwl:hasNarrowSynonym "activation of mitochondrial translation elongation", "activation of mitochondrial translational elongation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905084" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial translational elongation" ; rdfs:subClassOf obo:GO_0045901, obo:GO_1905082, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070125 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070125 ] ) ] . obo:GO_1905132 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of meiotic chromosome separation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2016-04-12T17:46:29Z" ; oboInOwl:hasExactSynonym "regulation of chromosome separation during meiosis", "regulation of meiotic chromosome resolution" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905132" ; a owl:Class ; rdfs:label "regulation of meiotic chromosome separation" ; rdfs:subClassOf obo:GO_1905818, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051307 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051307 ] ) ] . obo:GO_1905133 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2016-04-12T17:46:37Z" ; oboInOwl:hasExactSynonym "down regulation of chromosome separation during meiosis", "down regulation of meiotic chromosome resolution", "down regulation of meiotic chromosome separation", "down-regulation of chromosome separation during meiosis", "down-regulation of meiotic chromosome resolution", "down-regulation of meiotic chromosome separation", "downregulation of chromosome separation during meiosis", "downregulation of meiotic chromosome resolution", "downregulation of meiotic chromosome separation", "negative regulation of chromosome separation during meiosis", "negative regulation of meiotic chromosome resolution" ; oboInOwl:hasNarrowSynonym "inhibition of chromosome separation during meiosis", "inhibition of meiotic chromosome resolution", "inhibition of meiotic chromosome separation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905133" ; a owl:Class ; rdfs:label "negative regulation of meiotic chromosome separation" ; rdfs:subClassOf obo:GO_1905132, obo:GO_1905819, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051307 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051307 ] ) ] . obo:GO_1905134 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2016-04-12T17:46:45Z" ; oboInOwl:hasExactSynonym "positive regulation of chromosome separation during meiosis", "positive regulation of meiotic chromosome resolution", "up regulation of chromosome separation during meiosis", "up regulation of meiotic chromosome resolution", "up regulation of meiotic chromosome separation", "up-regulation of chromosome separation during meiosis", "up-regulation of meiotic chromosome resolution", "up-regulation of meiotic chromosome separation", "upregulation of chromosome separation during meiosis", "upregulation of meiotic chromosome resolution", "upregulation of meiotic chromosome separation" ; oboInOwl:hasNarrowSynonym "activation of chromosome separation during meiosis", "activation of meiotic chromosome resolution", "activation of meiotic chromosome separation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905134" ; a owl:Class ; rdfs:label "positive regulation of meiotic chromosome separation" ; rdfs:subClassOf obo:GO_1905132, obo:GO_1905820, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051307 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051307 ] ) ] . obo:GO_1905146 obo:IAO_0000115 "Any cellular protein catabolic process that takes place in a lysosome." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2016-04-14T12:50:34Z" ; oboInOwl:hasExactSynonym "cellular protein breakdown in lysosome", "cellular protein catabolic process in lysosome", "cellular protein catabolism in lysosome", "cellular protein degradation in lysosome", "lysosomal protein catabolism", "lysosomal protein degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "lysosomal proteolysis", "proteolysis within lysosome" ; oboInOwl:id "GO:1905146" ; a owl:Class ; rdfs:comment "Also consider annotating to the term 'autophagy ; GO:0006914' or one of its descendants." ; rdfs:label "lysosomal protein catabolic process" ; rdfs:subClassOf obo:GO_0007039, [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0030163 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005764 ] ) ] . obo:GO_1905153 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of membrane invagination." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2016-04-18T15:43:54Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905153" ; a owl:Class ; rdfs:label "regulation of membrane invagination" ; rdfs:subClassOf obo:GO_0051128, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010324 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010324 ] ) ] . obo:GO_1905154 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2016-04-18T15:44:04Z" ; oboInOwl:hasExactSynonym "down regulation of membrane invagination", "down-regulation of membrane invagination", "downregulation of membrane invagination" ; oboInOwl:hasNarrowSynonym "inhibition of membrane invagination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905154" ; a owl:Class ; rdfs:label "negative regulation of membrane invagination" ; rdfs:subClassOf obo:GO_0051129, obo:GO_1905153, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010324 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010324 ] ) ] . obo:GO_1905155 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of membrane invagination." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2016-04-18T15:44:12Z" ; oboInOwl:hasExactSynonym "up regulation of membrane invagination", "up-regulation of membrane invagination", "upregulation of membrane invagination" ; oboInOwl:hasNarrowSynonym "activation of membrane invagination" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905155" ; a owl:Class ; rdfs:label "positive regulation of membrane invagination" ; rdfs:subClassOf obo:GO_0051130, obo:GO_1905153, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010324 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010324 ] ) ] . obo:GO_1905165 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2016-04-26T12:10:01Z" ; oboInOwl:hasExactSynonym "regulation of cellular protein breakdown in lysosome", "regulation of cellular protein catabolic process in lysosome", "regulation of cellular protein catabolism in lysosome", "regulation of cellular protein degradation in lysosome", "regulation of lysosomal protein catabolism", "regulation of lysosomal protein degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of lysosomal proteolysis", "regulation of proteolysis within lysosome" ; oboInOwl:id "GO:1905165" ; a owl:Class ; rdfs:label "regulation of lysosomal protein catabolic process" ; rdfs:subClassOf obo:GO_1904350, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1905146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_1905146 ] ) ] . obo:GO_1905166 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2016-04-26T12:10:10Z" ; oboInOwl:hasExactSynonym "down regulation of cellular protein breakdown in lysosome", "down regulation of cellular protein catabolic process in lysosome", "down regulation of cellular protein catabolism in lysosome", "down regulation of cellular protein degradation in lysosome", "down regulation of lysosomal protein catabolic process", "down regulation of lysosomal protein catabolism", "down regulation of lysosomal protein degradation", "down-regulation of cellular protein breakdown in lysosome", "down-regulation of cellular protein catabolic process in lysosome", "down-regulation of cellular protein catabolism in lysosome", "down-regulation of cellular protein degradation in lysosome", "down-regulation of lysosomal protein catabolic process", "down-regulation of lysosomal protein catabolism", "down-regulation of lysosomal protein degradation", "downregulation of cellular protein breakdown in lysosome", "downregulation of cellular protein catabolic process in lysosome", "downregulation of cellular protein catabolism in lysosome", "downregulation of cellular protein degradation in lysosome", "downregulation of lysosomal protein catabolic process", "downregulation of lysosomal protein catabolism", "downregulation of lysosomal protein degradation", "negative regulation of cellular protein breakdown in lysosome", "negative regulation of cellular protein catabolic process in lysosome", "negative regulation of cellular protein catabolism in lysosome", "negative regulation of cellular protein degradation in lysosome", "negative regulation of lysosomal protein catabolism", "negative regulation of lysosomal protein degradation" ; oboInOwl:hasNarrowSynonym "inhibition of cellular protein breakdown in lysosome", "inhibition of cellular protein catabolic process in lysosome", "inhibition of cellular protein catabolism in lysosome", "inhibition of cellular protein degradation in lysosome", "inhibition of lysosomal protein catabolic process", "inhibition of lysosomal protein catabolism", "inhibition of lysosomal protein degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of lysosomal proteolysis", "down regulation of proteolysis within lysosome", "down-regulation of lysosomal proteolysis", "down-regulation of proteolysis within lysosome", "downregulation of lysosomal proteolysis", "downregulation of proteolysis within lysosome", "inhibition of lysosomal proteolysis", "inhibition of proteolysis within lysosome", "negative regulation of lysosomal proteolysis", "negative regulation of proteolysis within lysosome" ; oboInOwl:id "GO:1905166" ; a owl:Class ; rdfs:label "negative regulation of lysosomal protein catabolic process" ; rdfs:subClassOf obo:GO_1904351, obo:GO_1905165, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1905146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_1905146 ] ) ] . obo:GO_1905167 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2016-04-26T12:10:19Z" ; oboInOwl:hasExactSynonym "positive regulation of cellular protein breakdown in lysosome", "positive regulation of cellular protein catabolic process in lysosome", "positive regulation of cellular protein catabolism in lysosome", "positive regulation of cellular protein degradation in lysosome", "positive regulation of lysosomal protein catabolism", "positive regulation of lysosomal protein degradation", "up regulation of cellular protein breakdown in lysosome", "up regulation of cellular protein catabolic process in lysosome", "up regulation of cellular protein catabolism in lysosome", "up regulation of cellular protein degradation in lysosome", "up regulation of lysosomal protein catabolic process", "up regulation of lysosomal protein catabolism", "up regulation of lysosomal protein degradation", "up-regulation of cellular protein breakdown in lysosome", "up-regulation of cellular protein catabolic process in lysosome", "up-regulation of cellular protein catabolism in lysosome", "up-regulation of cellular protein degradation in lysosome", "up-regulation of lysosomal protein catabolic process", "up-regulation of lysosomal protein catabolism", "up-regulation of lysosomal protein degradation", "upregulation of cellular protein breakdown in lysosome", "upregulation of cellular protein catabolic process in lysosome", "upregulation of cellular protein catabolism in lysosome", "upregulation of cellular protein degradation in lysosome", "upregulation of lysosomal protein catabolic process", "upregulation of lysosomal protein catabolism", "upregulation of lysosomal protein degradation" ; oboInOwl:hasNarrowSynonym "activation of cellular protein breakdown in lysosome", "activation of cellular protein catabolic process in lysosome", "activation of cellular protein catabolism in lysosome", "activation of cellular protein degradation in lysosome", "activation of lysosomal protein catabolic process", "activation of lysosomal protein catabolism", "activation of lysosomal protein degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of lysosomal proteolysis", "activation of proteolysis within lysosome", "positive regulation of lysosomal proteolysis", "positive regulation of proteolysis within lysosome", "up regulation of lysosomal proteolysis", "up regulation of proteolysis within lysosome", "up-regulation of lysosomal proteolysis", "up-regulation of proteolysis within lysosome", "upregulation of lysosomal proteolysis", "upregulation of proteolysis within lysosome" ; oboInOwl:id "GO:1905167" ; a owl:Class ; rdfs:label "positive regulation of lysosomal protein catabolic process" ; rdfs:subClassOf obo:GO_1904352, obo:GO_1905165, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1905146 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_1905146 ] ) ] . obo:GO_1905213 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2016-06-03T08:41:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905213" ; a owl:Class ; rdfs:label "negative regulation of mitotic chromosome condensation" ; rdfs:subClassOf obo:GO_0010948, obo:GO_1902340, obo:GO_1903379, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007076 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007076 ] ) ] . obo:GO_1905268 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22766"^^xsd:anyURI ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-06-15T20:14:47Z" ; oboInOwl:hasAlternativeId "GO:0045798", "GO:1903309" ; oboInOwl:hasExactSynonym "down regulation of chromatin organisation", "down regulation of chromatin organization", "down regulation of establishment or maintenance of chromatin architecture", "down-regulation of chromatin organisation", "down-regulation of chromatin organization", "down-regulation of establishment or maintenance of chromatin architecture", "downregulation of chromatin organisation", "downregulation of chromatin organization", "downregulation of establishment or maintenance of chromatin architecture", "negative regulation of chromatin assembly/disassembly", "negative regulation of chromatin organisation", "negative regulation of establishment or maintenance of chromatin architecture" ; oboInOwl:hasNarrowSynonym "inhibition of chromatin assembly or disassembly", "inhibition of chromatin organisation", "inhibition of chromatin organization", "inhibition of establishment or maintenance of chromatin architecture" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of chromatin assembly or disassembly", "down-regulation of chromatin assembly or disassembly", "downregulation of chromatin assembly or disassembly", "negative regulation of chromatin assembly or disassembly", "negative regulation of chromatin modification" ; oboInOwl:id "GO:1905268" ; a owl:Class ; rdfs:label "negative regulation of chromatin organization" ; rdfs:subClassOf obo:GO_0051129, obo:GO_1902275, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006325 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006325 ] ) ] . obo:GO_1905269 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of chromatin organization." ; obo:IAO_0000233 "https://github.com/geneontology/go-ontology/issues/22766"^^xsd:anyURI ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-06-15T20:14:56Z" ; oboInOwl:hasAlternativeId "GO:0045799", "GO:1903310" ; oboInOwl:hasExactSynonym "positive regulation of chromatin organisation", "positive regulation of establishment or maintenance of chromatin architecture", "up regulation of chromatin organisation", "up regulation of chromatin organization", "up regulation of establishment or maintenance of chromatin architecture", "up-regulation of chromatin organisation", "up-regulation of chromatin organization", "up-regulation of establishment or maintenance of chromatin architecture", "upregulation of chromatin assembly or disassembly", "upregulation of chromatin organisation", "upregulation of chromatin organization", "upregulation of establishment or maintenance of chromatin architecture" ; oboInOwl:hasNarrowSynonym "activation of chromatin assembly or disassembly", "activation of chromatin organisation", "activation of chromatin organization", "activation of establishment or maintenance of chromatin architecture", "stimulation of chromatin assembly or disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of chromatin assembly or disassembly", "positive regulation of chromatin assembly/disassembly", "positive regulation of chromatin modification", "up regulation of chromatin assembly or disassembly", "up-regulation of chromatin assembly or disassembly" ; oboInOwl:id "GO:1905269" ; a owl:Class ; rdfs:label "positive regulation of chromatin organization" ; rdfs:subClassOf obo:GO_1902275, obo:GO_2001252, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006325 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006325 ] ) ] . obo:GO_1905427 obo:IAO_0000115 "Any intracellular signal transduction that is involved in positive regulation of cell growth." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2016-09-07T18:15:01Z" ; oboInOwl:hasExactSynonym "intracellular signal transduction involved in up regulation of cell growth", "intracellular signal transduction involved in up-regulation of cell growth", "intracellular signal transduction involved in upregulation of cell growth", "intracellular signaling chain involved in positive regulation of cell growth", "intracellular signaling chain involved in up regulation of cell growth", "intracellular signaling chain involved in up-regulation of cell growth", "intracellular signaling chain involved in upregulation of cell growth" ; oboInOwl:hasNarrowSynonym "intracellular protein kinase cascade involved in activation of cell growth", "intracellular protein kinase cascade involved in positive regulation of cell growth", "intracellular protein kinase cascade involved in stimulation of cell growth", "intracellular protein kinase cascade involved in up regulation of cell growth", "intracellular protein kinase cascade involved in up-regulation of cell growth", "intracellular protein kinase cascade involved in upregulation of cell growth", "intracellular signal transduction involved in activation of cell growth", "intracellular signal transduction involved in stimulation of cell growth", "intracellular signal transduction pathway involved in activation of cell growth", "intracellular signal transduction pathway involved in positive regulation of cell growth", "intracellular signal transduction pathway involved in stimulation of cell growth", "intracellular signal transduction pathway involved in up regulation of cell growth", "intracellular signal transduction pathway involved in up-regulation of cell growth", "intracellular signal transduction pathway involved in upregulation of cell growth", "intracellular signaling chain involved in activation of cell growth", "intracellular signaling chain involved in stimulation of cell growth", "protein kinase cascade involved in activation of cell growth", "protein kinase cascade involved in positive regulation of cell growth", "protein kinase cascade involved in stimulation of cell growth", "protein kinase cascade involved in up regulation of cell growth", "protein kinase cascade involved in up-regulation of cell growth", "protein kinase cascade involved in upregulation of cell growth", "signal transmission via intracellular cascade involved in activation of cell growth", "signal transmission via intracellular cascade involved in positive regulation of cell growth", "signal transmission via intracellular cascade involved in stimulation of cell growth", "signal transmission via intracellular cascade involved in up regulation of cell growth", "signal transmission via intracellular cascade involved in up-regulation of cell growth", "signal transmission via intracellular cascade involved in upregulation of cell growth" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "intracellular signaling cascade involved in activation of cell growth", "intracellular signaling cascade involved in positive regulation of cell growth", "intracellular signaling cascade involved in stimulation of cell growth", "intracellular signaling cascade involved in up regulation of cell growth", "intracellular signaling cascade involved in up-regulation of cell growth", "intracellular signaling cascade involved in upregulation of cell growth", "intracellular signaling pathway involved in activation of cell growth", "intracellular signaling pathway involved in positive regulation of cell growth", "intracellular signaling pathway involved in stimulation of cell growth", "intracellular signaling pathway involved in up regulation of cell growth", "intracellular signaling pathway involved in up-regulation of cell growth", "intracellular signaling pathway involved in upregulation of cell growth", "signal transduction via intracellular signaling cascade involved in activation of cell growth", "signal transduction via intracellular signaling cascade involved in positive regulation of cell growth", "signal transduction via intracellular signaling cascade involved in stimulation of cell growth", "signal transduction via intracellular signaling cascade involved in up regulation of cell growth", "signal transduction via intracellular signaling cascade involved in up-regulation of cell growth", "signal transduction via intracellular signaling cascade involved in upregulation of cell growth" ; oboInOwl:id "GO:1905427" ; a owl:Class ; rdfs:label "intracellular signal transduction involved in positive regulation of cell growth" ; rdfs:subClassOf obo:GO_0035556, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030307 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0035556 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0030307 ] ) ] . obo:GO_1905516 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of fertilization." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2016-09-30T14:32:32Z" ; oboInOwl:hasExactSynonym "positive regulation of syngamy", "up regulation of fertilization", "up regulation of syngamy", "up-regulation of fertilization", "up-regulation of syngamy", "upregulation of fertilization", "upregulation of syngamy" ; oboInOwl:hasNarrowSynonym "activation of fertilization", "activation of syngamy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905516" ; a owl:Class ; rdfs:label "positive regulation of fertilization" ; rdfs:subClassOf obo:GO_0080154, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009566 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0009566 ] ) ] . obo:GO_1905550 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum." ; oboInOwl:created_by "rz" ; oboInOwl:creation_date "2016-10-12T11:37:01Z" ; oboInOwl:hasExactSynonym "regulation of protein localisation in endoplasmic reticulum", "regulation of protein localization in ER", "regulation of protein localization in endoplasmic reticulum" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905550" ; a owl:Class ; rdfs:label "regulation of protein localization to endoplasmic reticulum" ; rdfs:subClassOf obo:GO_0032880, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070972 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0070972 ] ) ] . obo:GO_1905551 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum." ; oboInOwl:created_by "rz" ; oboInOwl:creation_date "2016-10-12T11:37:08Z" ; oboInOwl:hasExactSynonym "down regulation of protein localisation in endoplasmic reticulum", "down regulation of protein localization in ER", "down regulation of protein localization in endoplasmic reticulum", "down regulation of protein localization to endoplasmic reticulum", "down-regulation of protein localisation in endoplasmic reticulum", "down-regulation of protein localization in ER", "down-regulation of protein localization in endoplasmic reticulum", "down-regulation of protein localization to endoplasmic reticulum", "downregulation of protein localisation in endoplasmic reticulum", "downregulation of protein localization in ER", "downregulation of protein localization in endoplasmic reticulum", "downregulation of protein localization to endoplasmic reticulum", "negative regulation of protein localisation in endoplasmic reticulum", "negative regulation of protein localization in ER", "negative regulation of protein localization in endoplasmic reticulum" ; oboInOwl:hasNarrowSynonym "inhibition of protein localisation in endoplasmic reticulum", "inhibition of protein localization in ER", "inhibition of protein localization in endoplasmic reticulum", "inhibition of protein localization to endoplasmic reticulum" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905551" ; a owl:Class ; rdfs:label "negative regulation of protein localization to endoplasmic reticulum" ; rdfs:subClassOf obo:GO_1903828, obo:GO_1905550, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070972 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0070972 ] ) ] . obo:GO_1905552 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum." ; oboInOwl:created_by "rz" ; oboInOwl:creation_date "2016-10-12T11:37:16Z" ; oboInOwl:hasExactSynonym "positive regulation of protein localisation in endoplasmic reticulum", "positive regulation of protein localization in ER", "positive regulation of protein localization in endoplasmic reticulum", "up regulation of protein localisation in endoplasmic reticulum", "up regulation of protein localization in ER", "up regulation of protein localization in endoplasmic reticulum", "up regulation of protein localization to endoplasmic reticulum", "up-regulation of protein localisation in endoplasmic reticulum", "up-regulation of protein localization in ER", "up-regulation of protein localization in endoplasmic reticulum", "up-regulation of protein localization to endoplasmic reticulum", "upregulation of protein localisation in endoplasmic reticulum", "upregulation of protein localization in ER", "upregulation of protein localization in endoplasmic reticulum", "upregulation of protein localization to endoplasmic reticulum" ; oboInOwl:hasNarrowSynonym "activation of protein localisation in endoplasmic reticulum", "activation of protein localization in ER", "activation of protein localization in endoplasmic reticulum", "activation of protein localization to endoplasmic reticulum" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905552" ; a owl:Class ; rdfs:label "positive regulation of protein localization to endoplasmic reticulum" ; rdfs:subClassOf obo:GO_1903829, obo:GO_1905550, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070972 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0070972 ] ) ] . obo:GO_1905557 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2016-10-14T13:14:57Z" ; oboInOwl:hasExactSynonym "regulation of mitotic nuclear envelope breakdown", "regulation of mitotic nuclear envelope catabolism", "regulation of mitotic nuclear envelope degradation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905557" ; a owl:Class ; rdfs:label "regulation of mitotic nuclear envelope disassembly" ; rdfs:subClassOf obo:GO_0010549, obo:GO_0010564, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007077 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007077 ] ) ] . obo:GO_1905558 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2016-10-14T13:15:08Z" ; oboInOwl:hasExactSynonym "down regulation of mitotic nuclear envelope breakdown", "down regulation of mitotic nuclear envelope catabolism", "down regulation of mitotic nuclear envelope degradation", "down regulation of mitotic nuclear envelope disassembly", "down-regulation of mitotic nuclear envelope breakdown", "down-regulation of mitotic nuclear envelope catabolism", "down-regulation of mitotic nuclear envelope degradation", "down-regulation of mitotic nuclear envelope disassembly", "downregulation of mitotic nuclear envelope breakdown", "downregulation of mitotic nuclear envelope catabolism", "downregulation of mitotic nuclear envelope degradation", "downregulation of mitotic nuclear envelope disassembly", "negative regulation of mitotic nuclear envelope breakdown", "negative regulation of mitotic nuclear envelope catabolism", "negative regulation of mitotic nuclear envelope degradation" ; oboInOwl:hasNarrowSynonym "inhibition of mitotic nuclear envelope breakdown", "inhibition of mitotic nuclear envelope catabolism", "inhibition of mitotic nuclear envelope degradation", "inhibition of mitotic nuclear envelope disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905558" ; a owl:Class ; rdfs:label "negative regulation of mitotic nuclear envelope disassembly" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0051129, obo:GO_1905557, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007077 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007077 ] ) ] . obo:GO_1905559 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2016-10-14T13:15:17Z" ; oboInOwl:hasExactSynonym "positive regulation of mitotic nuclear envelope breakdown", "positive regulation of mitotic nuclear envelope catabolism", "positive regulation of mitotic nuclear envelope degradation", "up regulation of mitotic nuclear envelope breakdown", "up regulation of mitotic nuclear envelope catabolism", "up regulation of mitotic nuclear envelope degradation", "up regulation of mitotic nuclear envelope disassembly", "up-regulation of mitotic nuclear envelope breakdown", "up-regulation of mitotic nuclear envelope catabolism", "up-regulation of mitotic nuclear envelope degradation", "up-regulation of mitotic nuclear envelope disassembly", "upregulation of mitotic nuclear envelope breakdown", "upregulation of mitotic nuclear envelope catabolism", "upregulation of mitotic nuclear envelope degradation", "upregulation of mitotic nuclear envelope disassembly" ; oboInOwl:hasNarrowSynonym "activation of mitotic nuclear envelope breakdown", "activation of mitotic nuclear envelope catabolism", "activation of mitotic nuclear envelope degradation", "activation of mitotic nuclear envelope disassembly" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905559" ; a owl:Class ; rdfs:label "positive regulation of mitotic nuclear envelope disassembly" ; rdfs:subClassOf obo:GO_0051130, obo:GO_0090068, obo:GO_1905557, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007077 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007077 ] ) ] . obo:GO_1905627 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2016-10-31T14:26:20Z" ; oboInOwl:hasExactSynonym "regulation of serotonin anabolism", "regulation of serotonin biosynthesis", "regulation of serotonin formation", "regulation of serotonin synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905627" ; a owl:Class ; rdfs:label "regulation of serotonin biosynthetic process" ; rdfs:subClassOf obo:GO_0031326, obo:GO_0051171, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042427 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0042427 ] ) ] . obo:GO_1905628 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2016-10-31T14:26:28Z" ; oboInOwl:hasExactSynonym "down regulation of serotonin anabolism", "down regulation of serotonin biosynthesis", "down regulation of serotonin biosynthetic process", "down regulation of serotonin formation", "down regulation of serotonin synthesis", "down-regulation of serotonin anabolism", "down-regulation of serotonin biosynthesis", "down-regulation of serotonin biosynthetic process", "down-regulation of serotonin formation", "down-regulation of serotonin synthesis", "downregulation of serotonin anabolism", "downregulation of serotonin biosynthesis", "downregulation of serotonin biosynthetic process", "downregulation of serotonin formation", "downregulation of serotonin synthesis", "negative regulation of serotonin anabolism", "negative regulation of serotonin biosynthesis", "negative regulation of serotonin formation", "negative regulation of serotonin synthesis" ; oboInOwl:hasNarrowSynonym "inhibition of serotonin anabolism", "inhibition of serotonin biosynthesis", "inhibition of serotonin biosynthetic process", "inhibition of serotonin formation", "inhibition of serotonin synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905628" ; a owl:Class ; rdfs:label "negative regulation of serotonin biosynthetic process" ; rdfs:subClassOf obo:GO_0031327, obo:GO_0051172, obo:GO_1905627, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042427 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0042427 ] ) ] . obo:GO_1905629 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process." ; oboInOwl:created_by "pad" ; oboInOwl:creation_date "2016-10-31T14:26:36Z" ; oboInOwl:hasExactSynonym "positive regulation of serotonin anabolism", "positive regulation of serotonin biosynthesis", "positive regulation of serotonin formation", "positive regulation of serotonin synthesis", "up regulation of serotonin anabolism", "up regulation of serotonin biosynthesis", "up regulation of serotonin biosynthetic process", "up regulation of serotonin formation", "up regulation of serotonin synthesis", "up-regulation of serotonin anabolism", "up-regulation of serotonin biosynthesis", "up-regulation of serotonin biosynthetic process", "up-regulation of serotonin formation", "up-regulation of serotonin synthesis", "upregulation of serotonin anabolism", "upregulation of serotonin biosynthesis", "upregulation of serotonin biosynthetic process", "upregulation of serotonin formation", "upregulation of serotonin synthesis" ; oboInOwl:hasNarrowSynonym "activation of serotonin anabolism", "activation of serotonin biosynthesis", "activation of serotonin biosynthetic process", "activation of serotonin formation", "activation of serotonin synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905629" ; a owl:Class ; rdfs:label "positive regulation of serotonin biosynthetic process" ; rdfs:subClassOf obo:GO_0031328, obo:GO_0051173, obo:GO_1905627, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042427 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0042427 ] ) ] . obo:GO_1905637 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2016-11-03T20:23:57Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905637" ; a owl:Class ; rdfs:label "regulation of mitochondrial mRNA catabolic process" ; rdfs:subClassOf obo:GO_0000960, obo:GO_0061013, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000958 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000958 ] ) ] . obo:GO_1905638 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2016-11-03T20:24:05Z" ; oboInOwl:hasExactSynonym "down regulation of mitochondrial mRNA catabolic process", "down-regulation of mitochondrial mRNA catabolic process", "downregulation of mitochondrial mRNA catabolic process" ; oboInOwl:hasNarrowSynonym "inhibition of mitochondrial mRNA catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905638" ; a owl:Class ; rdfs:label "negative regulation of mitochondrial mRNA catabolic process" ; rdfs:subClassOf obo:GO_0000961, obo:GO_1902373, obo:GO_1905637, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000958 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000958 ] ) ] . obo:GO_1905639 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2016-11-03T20:24:13Z" ; oboInOwl:hasExactSynonym "up regulation of mitochondrial mRNA catabolic process", "up-regulation of mitochondrial mRNA catabolic process", "upregulation of mitochondrial mRNA catabolic process" ; oboInOwl:hasNarrowSynonym "activation of mitochondrial mRNA catabolic process" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905639" ; a owl:Class ; rdfs:label "positive regulation of mitochondrial mRNA catabolic process" ; rdfs:subClassOf obo:GO_0000962, obo:GO_0061014, obo:GO_1905637, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000958 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000958 ] ) ] . obo:GO_1905671 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of lysosome organization." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2016-11-11T22:01:04Z" ; oboInOwl:hasExactSynonym "regulation of lysosome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of lysosome organization and biogenesis" ; oboInOwl:id "GO:1905671" ; a owl:Class ; rdfs:label "regulation of lysosome organization" ; rdfs:subClassOf obo:GO_0044088, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007040 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007040 ] ) ] . obo:GO_1905672 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2016-11-11T22:01:12Z" ; oboInOwl:hasExactSynonym "down regulation of lysosome organisation", "down regulation of lysosome organization", "down-regulation of lysosome organisation", "down-regulation of lysosome organization", "downregulation of lysosome organisation", "downregulation of lysosome organization", "negative regulation of lysosome organisation" ; oboInOwl:hasNarrowSynonym "inhibition of lysosome organisation", "inhibition of lysosome organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of lysosome organization and biogenesis", "down-regulation of lysosome organization and biogenesis", "downregulation of lysosome organization and biogenesis", "inhibition of lysosome organization and biogenesis", "negative regulation of lysosome organization and biogenesis" ; oboInOwl:id "GO:1905672" ; a owl:Class ; rdfs:label "negative regulation of lysosome organization" ; rdfs:subClassOf obo:GO_0010639, obo:GO_1905671, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007040 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007040 ] ) ] . obo:GO_1905673 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of lysosome organization." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2016-11-11T22:01:20Z" ; oboInOwl:hasExactSynonym "positive regulation of lysosome organisation", "up regulation of lysosome organisation", "up regulation of lysosome organization", "up-regulation of lysosome organisation", "up-regulation of lysosome organization", "upregulation of lysosome organisation", "upregulation of lysosome organization" ; oboInOwl:hasNarrowSynonym "activation of lysosome organisation", "activation of lysosome organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of lysosome organization and biogenesis", "positive regulation of lysosome organization and biogenesis", "up regulation of lysosome organization and biogenesis", "up-regulation of lysosome organization and biogenesis", "upregulation of lysosome organization and biogenesis" ; oboInOwl:id "GO:1905673" ; a owl:Class ; rdfs:label "positive regulation of lysosome organization" ; rdfs:subClassOf obo:GO_0044090, obo:GO_1905671, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007040 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007040 ] ) ] . obo:GO_1905809 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2017-01-11T22:03:41Z" ; oboInOwl:hasExactSynonym "down regulation of synapse development", "down regulation of synapse organisation", "down regulation of synapse organization", "down-regulation of synapse development", "down-regulation of synapse organisation", "down-regulation of synapse organization", "downregulation of synapse development", "downregulation of synapse organisation", "downregulation of synapse organization", "negative regulation of synapse development", "negative regulation of synapse organisation" ; oboInOwl:hasNarrowSynonym "inhibition of synapse development", "inhibition of synapse organisation", "inhibition of synapse organization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of synapse morphogenesis", "down regulation of synapse organization and biogenesis", "down-regulation of synapse morphogenesis", "down-regulation of synapse organization and biogenesis", "downregulation of synapse morphogenesis", "downregulation of synapse organization and biogenesis", "inhibition of synapse morphogenesis", "inhibition of synapse organization and biogenesis", "negative regulation of synapse morphogenesis", "negative regulation of synapse organization and biogenesis" ; oboInOwl:id "GO:1905809" ; a owl:Class ; rdfs:label "negative regulation of synapse organization" ; rdfs:subClassOf obo:GO_0050807, obo:GO_0051129, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050808 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0050808 ] ) ] . obo:GO_1905818 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of chromosome separation." ; oboInOwl:created_by "bhm" ; oboInOwl:creation_date "2017-01-13T13:55:18Z" ; oboInOwl:hasNarrowSynonym "regulation of rDNA separation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of chromatid release" ; oboInOwl:id "GO:1905818" ; a owl:Class ; rdfs:label "regulation of chromosome separation" ; rdfs:subClassOf obo:GO_0051983, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051304 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0051304 ] ) ] . obo:GO_1905819 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation." ; oboInOwl:created_by "bhm" ; oboInOwl:creation_date "2017-01-13T13:55:27Z" ; oboInOwl:hasExactSynonym "down regulation of chromosome separation", "down-regulation of chromosome separation", "downregulation of chromosome separation" ; oboInOwl:hasNarrowSynonym "down regulation of rDNA separation", "down-regulation of rDNA separation", "downregulation of rDNA separation", "inhibition of chromosome separation", "inhibition of rDNA separation", "negative regulation of rDNA separation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of chromatid release", "down-regulation of chromatid release", "downregulation of chromatid release", "inhibition of chromatid release", "negative regulation of chromatid release" ; oboInOwl:id "GO:1905819" ; a owl:Class ; rdfs:label "negative regulation of chromosome separation" ; rdfs:subClassOf obo:GO_0051985, obo:GO_1905818, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051304 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051304 ] ) ] . obo:GO_1905820 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of chromosome separation." ; oboInOwl:created_by "bhm" ; oboInOwl:creation_date "2017-01-13T13:55:36Z" ; oboInOwl:hasExactSynonym "up regulation of chromosome separation", "up-regulation of chromosome separation", "upregulation of chromosome separation" ; oboInOwl:hasNarrowSynonym "activation of chromosome separation", "activation of rDNA separation", "positive regulation of rDNA separation", "up regulation of rDNA separation", "up-regulation of rDNA separation", "upregulation of rDNA separation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of chromatid release", "positive regulation of chromatid release", "up regulation of chromatid release", "up-regulation of chromatid release", "upregulation of chromatid release" ; oboInOwl:id "GO:1905820" ; a owl:Class ; rdfs:label "positive regulation of chromosome separation" ; rdfs:subClassOf obo:GO_0090068, obo:GO_1905818, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051304 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051304 ] ) ] . obo:GO_1905821 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of chromosome condensation." ; oboInOwl:created_by "bhm" ; oboInOwl:creation_date "2017-01-13T14:13:44Z" ; oboInOwl:hasExactSynonym "positive regulation of eukaryotic chromosome condensation", "positive regulation of nuclear chromosome condensation", "up regulation of chromosome condensation", "up regulation of eukaryotic chromosome condensation", "up regulation of nuclear chromosome condensation", "up-regulation of chromosome condensation", "up-regulation of eukaryotic chromosome condensation", "up-regulation of nuclear chromosome condensation", "upregulation of chromosome condensation", "upregulation of eukaryotic chromosome condensation", "upregulation of nuclear chromosome condensation" ; oboInOwl:hasNarrowSynonym "activation of chromosome condensation", "activation of eukaryotic chromosome condensation", "activation of nuclear chromosome condensation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905821" ; a owl:Class ; rdfs:label "positive regulation of chromosome condensation" ; rdfs:subClassOf obo:GO_0060623, obo:GO_2001252, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030261 ] ) ] . obo:GO_1905831 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-01-17T10:26:37Z" ; oboInOwl:hasExactSynonym "down regulation of bipolar spindle biosynthesis", "down regulation of bipolar spindle formation", "down regulation of spindle assembly", "down regulation of spindle biosynthesis", "down regulation of spindle formation", "down-regulation of bipolar spindle biosynthesis", "down-regulation of bipolar spindle formation", "down-regulation of spindle assembly", "down-regulation of spindle biosynthesis", "down-regulation of spindle formation", "downregulation of bipolar spindle biosynthesis", "downregulation of bipolar spindle formation", "downregulation of spindle assembly", "downregulation of spindle biosynthesis", "downregulation of spindle formation", "negative regulation of bipolar spindle biosynthesis", "negative regulation of bipolar spindle formation", "negative regulation of spindle biosynthesis", "negative regulation of spindle formation" ; oboInOwl:hasNarrowSynonym "inhibition of bipolar spindle biosynthesis", "inhibition of bipolar spindle formation", "inhibition of spindle assembly", "inhibition of spindle biosynthesis", "inhibition of spindle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905831" ; a owl:Class ; rdfs:label "negative regulation of spindle assembly" ; rdfs:subClassOf obo:GO_0010948, obo:GO_0051494, obo:GO_0090169, obo:GO_1902116, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051225 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051225 ] ) ] . obo:GO_1905832 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of spindle assembly." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-01-17T10:26:46Z" ; oboInOwl:hasExactSynonym "positive regulation of bipolar spindle biosynthesis", "positive regulation of bipolar spindle formation", "positive regulation of spindle biosynthesis", "positive regulation of spindle formation", "up regulation of bipolar spindle biosynthesis", "up regulation of bipolar spindle formation", "up regulation of spindle assembly", "up regulation of spindle biosynthesis", "up regulation of spindle formation", "up-regulation of bipolar spindle biosynthesis", "up-regulation of bipolar spindle formation", "up-regulation of spindle assembly", "up-regulation of spindle biosynthesis", "up-regulation of spindle formation", "upregulation of bipolar spindle biosynthesis", "upregulation of bipolar spindle formation", "upregulation of spindle assembly", "upregulation of spindle biosynthesis", "upregulation of spindle formation" ; oboInOwl:hasNarrowSynonym "activation of bipolar spindle biosynthesis", "activation of bipolar spindle formation", "activation of spindle assembly", "activation of spindle biosynthesis", "activation of spindle formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905832" ; a owl:Class ; rdfs:label "positive regulation of spindle assembly" ; rdfs:subClassOf obo:GO_0051495, obo:GO_0090068, obo:GO_0090169, obo:GO_1902117, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051225 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051225 ] ) ] . obo:GO_1905833 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-01-17T12:00:56Z" ; oboInOwl:hasExactSynonym "down regulation of microtubule nucleation", "down-regulation of microtubule nucleation", "downregulation of microtubule nucleation" ; oboInOwl:hasNarrowSynonym "inhibition of microtubule nucleation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905833" ; a owl:Class ; rdfs:label "negative regulation of microtubule nucleation" ; rdfs:subClassOf obo:GO_0010968, obo:GO_0031115, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007020 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007020 ] ) ] . obo:GO_1905843 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cellular response to gamma radiation." ; oboInOwl:created_by "rz" ; oboInOwl:creation_date "2017-01-19T10:24:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cellular response to gamma ray", "regulation of cellular response to gamma-ray photon" ; oboInOwl:id "GO:1905843" ; a owl:Class ; rdfs:label "regulation of cellular response to gamma radiation" ; rdfs:subClassOf obo:GO_0050794, obo:GO_2001228, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071480 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071480 ] ) ] . obo:GO_1905844 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to gamma radiation." ; oboInOwl:created_by "rz" ; oboInOwl:creation_date "2017-01-19T10:24:48Z" ; oboInOwl:hasExactSynonym "down regulation of cellular response to gamma radiation", "down-regulation of cellular response to gamma radiation", "downregulation of cellular response to gamma radiation" ; oboInOwl:hasNarrowSynonym "inhibition of cellular response to gamma radiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "down regulation of cellular response to gamma ray", "down regulation of cellular response to gamma-ray photon", "down-regulation of cellular response to gamma ray", "down-regulation of cellular response to gamma-ray photon", "downregulation of cellular response to gamma ray", "downregulation of cellular response to gamma-ray photon", "inhibition of cellular response to gamma ray", "inhibition of cellular response to gamma-ray photon", "negative regulation of cellular response to gamma ray", "negative regulation of cellular response to gamma-ray photon" ; oboInOwl:id "GO:1905844" ; a owl:Class ; rdfs:label "negative regulation of cellular response to gamma radiation" ; rdfs:subClassOf obo:GO_0048523, obo:GO_1905843, obo:GO_2001229, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071480 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071480 ] ) ] . obo:GO_1905845 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation." ; oboInOwl:created_by "rz" ; oboInOwl:creation_date "2017-01-19T10:24:57Z" ; oboInOwl:hasExactSynonym "up regulation of cellular response to gamma radiation", "up-regulation of cellular response to gamma radiation", "upregulation of cellular response to gamma radiation" ; oboInOwl:hasNarrowSynonym "activation of cellular response to gamma radiation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "activation of cellular response to gamma ray", "activation of cellular response to gamma-ray photon", "positive regulation of cellular response to gamma ray", "positive regulation of cellular response to gamma-ray photon", "up regulation of cellular response to gamma ray", "up regulation of cellular response to gamma-ray photon", "up-regulation of cellular response to gamma ray", "up-regulation of cellular response to gamma-ray photon", "upregulation of cellular response to gamma ray", "upregulation of cellular response to gamma-ray photon" ; oboInOwl:id "GO:1905845" ; a owl:Class ; rdfs:label "positive regulation of cellular response to gamma radiation" ; rdfs:subClassOf obo:GO_0048522, obo:GO_1905843, obo:GO_2001230, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071480 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071480 ] ) ] . obo:GO_1905851 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of backward locomotion." ; oboInOwl:created_by "rz" ; oboInOwl:creation_date "2017-01-23T11:04:16Z" ; oboInOwl:hasExactSynonym "down regulation of backward locomotion", "down-regulation of backward locomotion", "downregulation of backward locomotion" ; oboInOwl:hasNarrowSynonym "inhibition of backward locomotion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905851" ; a owl:Class ; rdfs:label "negative regulation of backward locomotion" ; rdfs:subClassOf obo:GO_0040013, obo:GO_0043058, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043057 ] ) ] . obo:GO_1905852 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of backward locomotion." ; oboInOwl:created_by "rz" ; oboInOwl:creation_date "2017-01-23T11:04:25Z" ; oboInOwl:hasExactSynonym "up regulation of backward locomotion", "up-regulation of backward locomotion", "upregulation of backward locomotion" ; oboInOwl:hasNarrowSynonym "activation of backward locomotion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905852" ; a owl:Class ; rdfs:label "positive regulation of backward locomotion" ; rdfs:subClassOf obo:GO_0040017, obo:GO_0043058, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043057 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043057 ] ) ] . obo:GO_1905879 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of oogenesis." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-01-31T09:31:05Z" ; oboInOwl:hasExactSynonym "regulation of ovum development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905879" ; a owl:Class ; rdfs:label "regulation of oogenesis" ; rdfs:subClassOf obo:GO_0051239, obo:GO_0060284, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048477 ] ) ] . obo:GO_1905880 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-01-31T09:31:15Z" ; oboInOwl:hasExactSynonym "down regulation of oogenesis", "down regulation of ovum development", "down-regulation of oogenesis", "down-regulation of ovum development", "downregulation of oogenesis", "downregulation of ovum development", "negative regulation of ovum development" ; oboInOwl:hasNarrowSynonym "inhibition of oogenesis", "inhibition of ovum development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905880" ; a owl:Class ; rdfs:label "negative regulation of oogenesis" ; rdfs:subClassOf obo:GO_0010721, obo:GO_0051241, obo:GO_1905879, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048477 ] ) ] . obo:GO_1905881 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of oogenesis." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-01-31T09:31:23Z" ; oboInOwl:hasExactSynonym "positive regulation of ovum development", "up regulation of oogenesis", "up regulation of ovum development", "up-regulation of oogenesis", "up-regulation of ovum development", "upregulation of oogenesis", "upregulation of ovum development" ; oboInOwl:hasNarrowSynonym "activation of oogenesis", "activation of ovum development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905881" ; a owl:Class ; rdfs:label "positive regulation of oogenesis" ; rdfs:subClassOf obo:GO_0010720, obo:GO_0051240, obo:GO_1905879, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048477 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048477 ] ) ] . obo:GO_1905897 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of response to endoplasmic reticulum stress." ; oboInOwl:created_by "bc" ; oboInOwl:creation_date "2017-02-01T11:42:55Z" ; oboInOwl:hasExactSynonym "regulation of ER stress response", "regulation of cellular response to endoplasmic reticulum stress", "regulation of response to ER stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905897" ; a owl:Class ; rdfs:label "regulation of response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0080135, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034976 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0034976 ] ) ] . obo:GO_1905898 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress." ; oboInOwl:created_by "bc" ; oboInOwl:creation_date "2017-02-01T11:43:03Z" ; oboInOwl:hasExactSynonym "positive regulation of ER stress response", "positive regulation of cellular response to endoplasmic reticulum stress", "positive regulation of response to ER stress", "up regulation of ER stress response", "up regulation of cellular response to endoplasmic reticulum stress", "up regulation of response to ER stress", "up regulation of response to endoplasmic reticulum stress", "up-regulation of ER stress response", "up-regulation of cellular response to endoplasmic reticulum stress", "up-regulation of response to ER stress", "up-regulation of response to endoplasmic reticulum stress", "upregulation of ER stress response", "upregulation of cellular response to endoplasmic reticulum stress", "upregulation of response to ER stress", "upregulation of response to endoplasmic reticulum stress" ; oboInOwl:hasNarrowSynonym "activation of ER stress response", "activation of cellular response to endoplasmic reticulum stress", "activation of response to ER stress", "activation of response to endoplasmic reticulum stress" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905898" ; a owl:Class ; rdfs:label "positive regulation of response to endoplasmic reticulum stress" ; rdfs:subClassOf obo:GO_0048522, obo:GO_0048584, obo:GO_1905897, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034976 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0034976 ] ) ] . obo:GO_1905902 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mesoderm formation." ; oboInOwl:created_by "rph" ; oboInOwl:creation_date "2017-02-03T12:28:20Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905902" ; a owl:Class ; rdfs:label "regulation of mesoderm formation" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001707 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001707 ] ) ] . obo:GO_1905903 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation." ; oboInOwl:created_by "rph" ; oboInOwl:creation_date "2017-02-03T12:28:29Z" ; oboInOwl:hasExactSynonym "down regulation of mesoderm formation", "down-regulation of mesoderm formation", "downregulation of mesoderm formation" ; oboInOwl:hasNarrowSynonym "inhibition of mesoderm formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905903" ; a owl:Class ; rdfs:label "negative regulation of mesoderm formation" ; rdfs:subClassOf obo:GO_1905902, obo:GO_2000381, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001707 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001707 ] ) ] . obo:GO_1905904 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mesoderm formation." ; oboInOwl:created_by "rph" ; oboInOwl:creation_date "2017-02-03T12:28:38Z" ; oboInOwl:hasExactSynonym "up regulation of mesoderm formation", "up-regulation of mesoderm formation", "upregulation of mesoderm formation" ; oboInOwl:hasNarrowSynonym "activation of mesoderm formation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905904" ; a owl:Class ; rdfs:label "positive regulation of mesoderm formation" ; rdfs:subClassOf obo:GO_1905902, obo:GO_2000382, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001707 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001707 ] ) ] . obo:GO_1905909 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of dauer entry." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-02-06T15:34:01Z" ; oboInOwl:hasExactSynonym "regulation of nematode entry into dormancy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905909" ; a owl:Class ; rdfs:label "regulation of dauer entry" ; rdfs:subClassOf obo:GO_0061065, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043053 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043053 ] ) ] . obo:GO_1905910 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of dauer entry." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-02-06T15:34:11Z" ; oboInOwl:hasExactSynonym "down regulation of dauer entry", "down regulation of nematode entry into dormancy", "down-regulation of dauer entry", "down-regulation of nematode entry into dormancy", "downregulation of dauer entry", "downregulation of nematode entry into dormancy", "negative regulation of nematode entry into dormancy" ; oboInOwl:hasNarrowSynonym "inhibition of dauer entry", "inhibition of nematode entry into dormancy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905910" ; a owl:Class ; rdfs:label "negative regulation of dauer entry" ; rdfs:subClassOf obo:GO_0061067, obo:GO_1905909, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043053 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043053 ] ) ] . obo:GO_1905911 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of dauer entry." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-02-06T15:34:20Z" ; oboInOwl:hasExactSynonym "positive regulation of nematode entry into dormancy", "up regulation of dauer entry", "up regulation of nematode entry into dormancy", "up-regulation of dauer entry", "up-regulation of nematode entry into dormancy", "upregulation of dauer entry", "upregulation of nematode entry into dormancy" ; oboInOwl:hasNarrowSynonym "activation of dauer entry", "activation of nematode entry into dormancy" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905911" ; a owl:Class ; rdfs:label "positive regulation of dauer entry" ; rdfs:subClassOf obo:GO_0051094, obo:GO_1905909, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043053 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043053 ] ) ] . obo:GO_1905939 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of gonad development." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-02-09T17:01:50Z" ; oboInOwl:hasExactSynonym "regulation of gonadogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905939" ; a owl:Class ; rdfs:label "regulation of gonad development" ; rdfs:subClassOf obo:GO_0050793, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008406 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008406 ] ) ] . obo:GO_1905940 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-02-09T17:01:59Z" ; oboInOwl:hasExactSynonym "down regulation of gonad development", "down regulation of gonadogenesis", "down-regulation of gonad development", "down-regulation of gonadogenesis", "downregulation of gonad development", "downregulation of gonadogenesis", "negative regulation of gonadogenesis" ; oboInOwl:hasNarrowSynonym "inhibition of gonad development", "inhibition of gonadogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905940" ; a owl:Class ; rdfs:label "negative regulation of gonad development" ; rdfs:subClassOf obo:GO_0051093, obo:GO_0051241, obo:GO_1905939, obo:GO_2000242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008406 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008406 ] ) ] . obo:GO_1905941 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of gonad development." ; oboInOwl:created_by "hbye" ; oboInOwl:creation_date "2017-02-09T17:02:08Z" ; oboInOwl:hasExactSynonym "positive regulation of gonadogenesis", "up regulation of gonad development", "up regulation of gonadogenesis", "up-regulation of gonad development", "up-regulation of gonadogenesis", "upregulation of gonad development", "upregulation of gonadogenesis" ; oboInOwl:hasNarrowSynonym "activation of gonad development", "activation of gonadogenesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905941" ; a owl:Class ; rdfs:label "positive regulation of gonad development" ; rdfs:subClassOf obo:GO_0051094, obo:GO_0051240, obo:GO_1905939, obo:GO_2000243, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008406 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008406 ] ) ] . obo:GO_1905951 obo:IAO_0000115 "Any DNA recombination that takes place in mitochondrion." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2017-02-19T10:48:17Z" ; oboInOwl:hasExactSynonym "DNA recombination in mitochondria" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1905951" ; a owl:Class ; rdfs:label "mitochondrion DNA recombination" ; rdfs:subClassOf obo:GO_0006310, obo:GO_0032042 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0006310 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_1990138 obo:IAO_0000115 "Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2013-07-08T08:40:45Z" ; oboInOwl:hasExactSynonym "neuron process extension", "neuron protrusion extension", "neuronal cell projection extension" ; oboInOwl:hasNarrowSynonym "neurite extension" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1990138" ; a owl:Class ; rdfs:label "neuron projection extension" ; rdfs:subClassOf obo:GO_0048588, obo:GO_0060560, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0048812 ] . obo:GO_1990574 obo:IAO_0000115 "Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell." ; oboInOwl:created_by "vw" ; oboInOwl:creation_date "2014-12-04T09:55:09Z" ; oboInOwl:hasOBONamespace "cellular_component" ; oboInOwl:id "GO:1990574" ; a owl:Class ; rdfs:label "meiotic spindle astral microtubule" ; rdfs:subClassOf obo:GO_0000235, [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072687 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0000235 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:GO_0072687 ] ) ] . obo:GO_1990840 obo:IAO_0000115 "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties." ; oboInOwl:created_by "sl" ; oboInOwl:creation_date "2015-08-27T20:02:21Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:1990840" ; a owl:Class ; rdfs:comment "This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity." ; rdfs:label "response to lectin" ; rdfs:subClassOf obo:GO_0009607 . obo:GO_2000001 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of a DNA damage checkpoint." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-07-15T03:25:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of DNA damage response, signal transduction resulting in cell cycle arrest" ; oboInOwl:id "GO:2000001" ; a owl:Class ; rdfs:label "regulation of DNA damage checkpoint" ; rdfs:subClassOf obo:GO_0080135, obo:GO_1901976, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000077 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000077 ] ) ] . obo:GO_2000002 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-07-15T03:25:06Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of DNA damage response, signal transduction resulting in cell cycle arrest" ; oboInOwl:id "GO:2000002" ; a owl:Class ; rdfs:label "negative regulation of DNA damage checkpoint" ; rdfs:subClassOf obo:GO_1901977, obo:GO_2000001, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000077 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000077 ] ) ] . obo:GO_2000003 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-07-15T03:25:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of DNA damage response, signal transduction resulting in cell cycle arrest" ; oboInOwl:id "GO:2000003" ; a owl:Class ; rdfs:label "positive regulation of DNA damage checkpoint" ; rdfs:subClassOf obo:GO_1901978, obo:GO_2000001, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000077 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000077 ] ) ] . obo:GO_2000018 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of male gonad development." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-07-15T03:29:05Z" ; oboInOwl:hasExactSynonym "regulation of testicular development", "regulation of testis development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000018" ; a owl:Class ; rdfs:label "regulation of male gonad development" ; rdfs:subClassOf obo:GO_1905939, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0008584 ] ) ] . obo:GO_2000019 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-07-15T03:29:10Z" ; oboInOwl:hasExactSynonym "negative regulation of testicular development", "negative regulation of testis development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000019" ; a owl:Class ; rdfs:label "negative regulation of male gonad development" ; rdfs:subClassOf obo:GO_1905940, obo:GO_2000018, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0008584 ] ) ] . obo:GO_2000020 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of male gonad development." ; oboInOwl:created_by "jl" ; oboInOwl:creation_date "2010-07-15T03:29:13Z" ; oboInOwl:hasExactSynonym "positive regulation of testicular development", "positive regulation of testis development" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000020" ; a owl:Class ; rdfs:label "positive regulation of male gonad development" ; rdfs:subClassOf obo:GO_1905941, obo:GO_2000018, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008584 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0008584 ] ) ] . obo:GO_2000026 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of multicellular organismal development." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-08-05T11:25:59Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000026" ; a owl:Class ; rdfs:label "regulation of multicellular organismal development" ; rdfs:subClassOf obo:GO_0050793, obo:GO_0051239, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007275 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007275 ] ) ] . obo:GO_2000045 obo:IAO_0000115 "Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-08-19T09:10:56Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000045" ; a owl:Class ; rdfs:comment "Note that this process is usually achieved by the regulation of the G1 cyclin-dependent protein kinase, consider annotating to the child term 'regulation of cyclin-dependent protein kinase activity involved in G1/S ; GO:0031657'." ; rdfs:label "regulation of G1/S transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_1901990, obo:GO_1902806, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000082 ] ) ] . obo:GO_2000070 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of response to water deprivation." ; oboInOwl:created_by "tb" ; oboInOwl:creation_date "2010-08-23T11:32:32Z" ; oboInOwl:hasExactSynonym "regulation of response to dehydration", "regulation of response to drought", "regulation of response to thirst" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of drought tolerance" ; oboInOwl:id "GO:2000070" ; a owl:Class ; rdfs:label "regulation of response to water deprivation" ; rdfs:subClassOf obo:GO_0080134, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0009414 ] ) ] . obo:GO_2000104 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-15T01:37:05Z" ; oboInOwl:hasExactSynonym "negative regulation of DNA-dependent DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000104" ; a owl:Class ; rdfs:label "negative regulation of DNA-templated DNA replication" ; rdfs:subClassOf obo:GO_0008156, obo:GO_0090329, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0006261 ] ) ] . obo:GO_2000105 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-15T01:37:10Z" ; oboInOwl:hasExactSynonym "positive regulation of DNA-dependent DNA replication" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000105" ; a owl:Class ; rdfs:label "positive regulation of DNA-templated DNA replication" ; rdfs:subClassOf obo:GO_0045740, obo:GO_0090329, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006261 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0006261 ] ) ] . obo:GO_2000114 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of establishment of cell polarity." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2010-09-16T01:22:36Z" ; oboInOwl:hasExactSynonym "regulation of cell polarization" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of bud site selection/establishment of cell polarity" ; oboInOwl:id "GO:2000114" ; a owl:Class ; rdfs:label "regulation of establishment of cell polarity" ; rdfs:subClassOf obo:GO_0032878, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030010 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030010 ] ) ] . obo:GO_2000134 obo:IAO_0000115 "Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-09-29T09:38:51Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000134" ; a owl:Class ; rdfs:label "negative regulation of G1/S transition of mitotic cell cycle" ; rdfs:subClassOf obo:GO_1901991, obo:GO_1902807, obo:GO_2000045, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000082 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000082 ] ) ] . obo:GO_2000145 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of cell motility." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-01T09:41:21Z" ; oboInOwl:hasExactSynonym "regulation of cell locomotion", "regulation of movement of a cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of cell movement" ; oboInOwl:id "GO:2000145" ; a owl:Class ; rdfs:label "regulation of cell motility" ; rdfs:subClassOf obo:GO_0040012, obo:GO_0050794, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048870 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0048870 ] ) ] . obo:GO_2000146 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-01T09:41:26Z" ; oboInOwl:hasExactSynonym "negative regulation of cell locomotion", "negative regulation of movement of a cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of cell movement" ; oboInOwl:id "GO:2000146" ; a owl:Class ; rdfs:label "negative regulation of cell motility" ; rdfs:subClassOf obo:GO_0040013, obo:GO_0048523, obo:GO_2000145, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048870 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0048870 ] ) ] . obo:GO_2000147 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of cell motility." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-01T09:41:30Z" ; oboInOwl:hasExactSynonym "positive regulation of cell locomotion", "positive regulation of movement of a cell" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of cell movement" ; oboInOwl:id "GO:2000147" ; a owl:Class ; rdfs:label "positive regulation of cell motility" ; rdfs:subClassOf obo:GO_0040017, obo:GO_0048522, obo:GO_2000145, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048870 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0048870 ] ) ] . obo:GO_2000171 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development." ; oboInOwl:created_by "rl" ; oboInOwl:creation_date "2010-10-07T10:53:15Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000171" ; a owl:Class ; rdfs:label "negative regulation of dendrite development" ; rdfs:subClassOf obo:GO_0010977, obo:GO_0050773, obo:GO_0051093, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016358 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016358 ] ) ] . obo:GO_2000197 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-26T10:35:48Z" ; oboInOwl:hasExactSynonym "regulation of RNP localization", "regulation of cellular ribonucleoprotein complex localization", "regulation of establishment and maintenance of ribonucleoprotein complex localization", "regulation of ribonucleoprotein complex localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000197" ; a owl:Class ; rdfs:label "regulation of ribonucleoprotein complex localization" ; rdfs:subClassOf obo:GO_0060341, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071166 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071166 ] ) ] . obo:GO_2000198 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-26T10:35:52Z" ; oboInOwl:hasExactSynonym "negative regulation of RNP localization", "negative regulation of cellular ribonucleoprotein complex localization", "negative regulation of establishment and maintenance of ribonucleoprotein complex localization", "negative regulation of ribonucleoprotein complex localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000198" ; a owl:Class ; rdfs:label "negative regulation of ribonucleoprotein complex localization" ; rdfs:subClassOf obo:GO_0048523, obo:GO_2000197, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071166 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071166 ] ) ] . obo:GO_2000199 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-10-26T10:35:55Z" ; oboInOwl:hasExactSynonym "positive regulation of RNP localization", "positive regulation of cellular ribonucleoprotein complex localization", "positive regulation of establishment and maintenance of ribonucleoprotein complex localization", "positive regulation of ribonucleoprotein complex localisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000199" ; a owl:Class ; rdfs:label "positive regulation of ribonucleoprotein complex localization" ; rdfs:subClassOf obo:GO_0048522, obo:GO_2000197, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071166 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071166 ] ) ] . obo:GO_2000241 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of reproductive process." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-10T02:44:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000241" ; a owl:Class ; rdfs:label "regulation of reproductive process" ; rdfs:subClassOf obo:GO_0050789, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0022414 ] ) ] . obo:GO_2000242 obo:IAO_0000115 "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-10T02:44:05Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000242" ; a owl:Class ; rdfs:label "negative regulation of reproductive process" ; rdfs:subClassOf obo:GO_0048519, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0022414 ] ) ] . obo:GO_2000243 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of reproductive process." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2010-11-10T02:44:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000243" ; a owl:Class ; rdfs:label "positive regulation of reproductive process" ; rdfs:subClassOf obo:GO_0048518, obo:GO_2000241, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022414 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0022414 ] ) ] . obo:GO_2000252 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2010-11-18T11:24:14Z" ; oboInOwl:hasExactSynonym "negative regulation of behavioral response to food", "negative regulation of behavioural response to food", "negative regulation of feeding behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of drinking", "negative regulation of eating" ; oboInOwl:id "GO:2000252" ; a owl:Class ; rdfs:label "negative regulation of feeding behavior" ; rdfs:subClassOf obo:GO_0048521, obo:GO_0060259, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007631 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007631 ] ) ] . obo:GO_2000253 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of feeding behavior." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2010-11-18T11:24:18Z" ; oboInOwl:hasExactSynonym "positive regulation of behavioral response to food", "positive regulation of behavioural response to food", "positive regulation of feeding behaviour" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of drinking", "positive regulation of eating" ; oboInOwl:id "GO:2000253" ; a owl:Class ; rdfs:label "positive regulation of feeding behavior" ; rdfs:subClassOf obo:GO_0048520, obo:GO_0060259, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007631 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007631 ] ) ] . obo:GO_2000278 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of DNA biosynthetic process." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2010-12-08T04:48:15Z" ; oboInOwl:hasExactSynonym "regulation of DNA anabolism", "regulation of DNA biosynthesis", "regulation of DNA formation", "regulation of DNA synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000278" ; a owl:Class ; rdfs:label "regulation of DNA biosynthetic process" ; rdfs:subClassOf obo:GO_0010556, obo:GO_0051052, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071897 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0071897 ] ) ] . obo:GO_2000279 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2010-12-08T04:48:20Z" ; oboInOwl:hasExactSynonym "negative regulation of DNA anabolism", "negative regulation of DNA biosynthesis", "negative regulation of DNA formation", "negative regulation of DNA synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000279" ; a owl:Class ; rdfs:label "negative regulation of DNA biosynthetic process" ; rdfs:subClassOf obo:GO_0010558, obo:GO_0051053, obo:GO_2000278, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071897 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0071897 ] ) ] . obo:GO_2000292 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of defecation." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-12-21T09:23:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000292" ; a owl:Class ; rdfs:label "regulation of defecation" ; rdfs:subClassOf obo:GO_0044058, obo:GO_0044062, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030421 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0030421 ] ) ] . obo:GO_2000293 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of defecation." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-12-21T09:23:13Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000293" ; a owl:Class ; rdfs:label "negative regulation of defecation" ; rdfs:subClassOf obo:GO_0051048, obo:GO_0060457, obo:GO_2000292, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030421 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0030421 ] ) ] . obo:GO_2000294 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of defecation." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2010-12-21T09:23:16Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000294" ; a owl:Class ; rdfs:label "positive regulation of defecation" ; rdfs:subClassOf obo:GO_0051047, obo:GO_0060456, obo:GO_2000292, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030421 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0030421 ] ) ] . obo:GO_2000300 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-01-03T08:20:40Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000300" ; oboInOwl:inSubset go:goslim_synapse ; a owl:Class ; rdfs:label "regulation of synaptic vesicle exocytosis" ; rdfs:subClassOf obo:GO_0046928, obo:GO_1903305, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016079 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0016079 ] ) ] . obo:GO_2000301 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-01-03T08:21:00Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000301" ; a owl:Class ; rdfs:label "negative regulation of synaptic vesicle exocytosis" ; rdfs:subClassOf obo:GO_1903306, obo:GO_2000300, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016079 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0016079 ] ) ] . obo:GO_2000302 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-01-03T08:21:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000302" ; a owl:Class ; rdfs:label "positive regulation of synaptic vesicle exocytosis" ; rdfs:subClassOf obo:GO_0001956, obo:GO_1903307, obo:GO_2000300, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016079 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0016079 ] ) ] . obo:GO_2000380 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of mesoderm development." ; oboInOwl:created_by "vk" ; oboInOwl:creation_date "2011-02-15T03:09:46Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000380" ; a owl:Class ; rdfs:label "regulation of mesoderm development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007498 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007498 ] ) ] . obo:GO_2000381 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development." ; oboInOwl:created_by "vk" ; oboInOwl:creation_date "2011-02-15T03:10:02Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000381" ; a owl:Class ; rdfs:label "negative regulation of mesoderm development" ; rdfs:subClassOf obo:GO_0051093, obo:GO_2000380, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007498 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007498 ] ) ] . obo:GO_2000382 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of mesoderm development." ; oboInOwl:created_by "vk" ; oboInOwl:creation_date "2011-02-15T03:10:12Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000382" ; a owl:Class ; rdfs:label "positive regulation of mesoderm development" ; rdfs:subClassOf obo:GO_0051094, obo:GO_2000380, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007498 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007498 ] ) ] . obo:GO_2000383 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of ectoderm development." ; oboInOwl:created_by "vk" ; oboInOwl:creation_date "2011-02-15T03:17:10Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000383" ; a owl:Class ; rdfs:label "regulation of ectoderm development" ; rdfs:subClassOf obo:GO_0050793, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0007398 ] ) ] . obo:GO_2000384 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development." ; oboInOwl:created_by "vk" ; oboInOwl:creation_date "2011-02-15T03:17:27Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000384" ; a owl:Class ; rdfs:label "negative regulation of ectoderm development" ; rdfs:subClassOf obo:GO_0051093, obo:GO_2000383, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007398 ] ) ] . obo:GO_2000385 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of ectoderm development." ; oboInOwl:created_by "vk" ; oboInOwl:creation_date "2011-02-15T03:17:39Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000385" ; a owl:Class ; rdfs:label "positive regulation of ectoderm development" ; rdfs:subClassOf obo:GO_0051094, obo:GO_2000383, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007398 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007398 ] ) ] . obo:GO_2000425 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of apoptotic cell clearance." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-02-25T11:50:11Z" ; oboInOwl:hasExactSynonym "regulation of apoptotic cell removal", "regulation of efferocytosis", "regulation of programmed cell clearance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000425" ; a owl:Class ; rdfs:label "regulation of apoptotic cell clearance" ; rdfs:subClassOf obo:GO_0050764, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043277 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0043277 ] ) ] . obo:GO_2000426 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-02-25T11:50:39Z" ; oboInOwl:hasExactSynonym "negative regulation of apoptotic cell removal", "negative regulation of efferocytosis", "negative regulation of programmed cell clearance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000426" ; a owl:Class ; rdfs:label "negative regulation of apoptotic cell clearance" ; rdfs:subClassOf obo:GO_0050765, obo:GO_2000425, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043277 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0043277 ] ) ] . obo:GO_2000427 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-02-25T11:50:59Z" ; oboInOwl:hasExactSynonym "positive regulation of apoptotic cell removal", "positive regulation of efferocytosis", "positive regulation of programmed cell clearance" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000427" ; a owl:Class ; rdfs:label "positive regulation of apoptotic cell clearance" ; rdfs:subClassOf obo:GO_0050766, obo:GO_2000425, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043277 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0043277 ] ) ] . obo:GO_2000542 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2011-04-01T04:10:08Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000542" ; a owl:Class ; rdfs:label "negative regulation of gastrulation" ; rdfs:subClassOf obo:GO_0010470, obo:GO_0045992, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0007369 ] ) ] . obo:GO_2000543 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of gastrulation." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2011-04-01T04:10:15Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000543" ; a owl:Class ; rdfs:label "positive regulation of gastrulation" ; rdfs:subClassOf obo:GO_0010470, obo:GO_0040019, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007369 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0007369 ] ) ] . obo:GO_2000573 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2011-04-04T10:01:20Z" ; oboInOwl:hasExactSynonym "positive regulation of DNA anabolism", "positive regulation of DNA biosynthesis", "positive regulation of DNA formation", "positive regulation of DNA synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000573" ; a owl:Class ; rdfs:label "positive regulation of DNA biosynthetic process" ; rdfs:subClassOf obo:GO_0010557, obo:GO_0051054, obo:GO_2000278, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071897 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0071897 ] ) ] . obo:GO_2000622 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-04-18T03:32:42Z" ; oboInOwl:hasExactSynonym "regulation of mRNA breakdown, nonsense-mediated decay", "regulation of mRNA catabolic process, nonsense-mediated", "regulation of mRNA catabolism, nonsense-mediated", "regulation of mRNA degradation, nonsense-mediated decay", "regulation of nonsense-mediated mRNA decay", "regulation of nuclear mRNA catabolic process, nonsense-mediated decay" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000622" ; a owl:Class ; rdfs:label "regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ; rdfs:subClassOf obo:GO_0061013, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000184 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0000184 ] ) ] . obo:GO_2000623 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-04-18T03:32:46Z" ; oboInOwl:hasExactSynonym "negative regulation of mRNA breakdown, nonsense-mediated decay", "negative regulation of mRNA catabolic process, nonsense-mediated", "negative regulation of mRNA catabolism, nonsense-mediated", "negative regulation of mRNA degradation, nonsense-mediated decay", "negative regulation of nonsense-mediated mRNA decay", "negative regulation of nuclear mRNA catabolic process, nonsense-mediated decay" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000623" ; a owl:Class ; rdfs:label "negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ; rdfs:subClassOf obo:GO_1902373, obo:GO_2000622, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000184 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0000184 ] ) ] . obo:GO_2000624 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-04-18T03:32:49Z" ; oboInOwl:hasExactSynonym "positive regulation of mRNA breakdown, nonsense-mediated decay", "positive regulation of mRNA catabolic process, nonsense-mediated", "positive regulation of mRNA catabolism, nonsense-mediated", "positive regulation of mRNA degradation, nonsense-mediated decay", "positive regulation of nonsense-mediated mRNA decay", "positive regulation of nuclear mRNA catabolic process, nonsense-mediated decay" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000624" ; a owl:Class ; rdfs:label "positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" ; rdfs:subClassOf obo:GO_0061014, obo:GO_2000622, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000184 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0000184 ] ) ] . obo:GO_2000746 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of defecation rhythm." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-15T03:23:07Z" ; oboInOwl:hasExactSynonym "regulation of DMP", "regulation of defecation cycle", "regulation of defecation motor program" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of defecation behavior" ; oboInOwl:id "GO:2000746" ; a owl:Class ; rdfs:label "regulation of defecation rhythm" ; rdfs:subClassOf obo:GO_2000292, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035882 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0035882 ] ) ] . obo:GO_2000747 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-15T03:23:10Z" ; oboInOwl:hasExactSynonym "negative regulation of DMP", "negative regulation of defecation cycle", "negative regulation of defecation motor program" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of defecation behavior" ; oboInOwl:id "GO:2000747" ; a owl:Class ; rdfs:label "negative regulation of defecation rhythm" ; rdfs:subClassOf obo:GO_2000293, obo:GO_2000746, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035882 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0035882 ] ) ] . obo:GO_2000748 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of defecation rhythm." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-06-15T03:23:13Z" ; oboInOwl:hasExactSynonym "positive regulation of DMP", "positive regulation of defecation cycle", "positive regulation of defecation motor program" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of defecation behavior" ; oboInOwl:id "GO:2000748" ; a owl:Class ; rdfs:label "positive regulation of defecation rhythm" ; rdfs:subClassOf obo:GO_2000294, obo:GO_2000746, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035882 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0035882 ] ) ] . obo:GO_2000807 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of synaptic vesicle clustering." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-07-06T09:50:30Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000807" ; a owl:Class ; rdfs:label "regulation of synaptic vesicle clustering" ; rdfs:subClassOf obo:GO_0032879, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097091 ] ) ] . obo:GO_2000808 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-07-06T09:50:34Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000808" ; a owl:Class ; rdfs:label "negative regulation of synaptic vesicle clustering" ; rdfs:subClassOf obo:GO_0051051, obo:GO_2000807, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097091 ] ) ] . obo:GO_2000809 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-07-06T09:50:37Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000809" ; a owl:Class ; rdfs:label "positive regulation of synaptic vesicle clustering" ; rdfs:subClassOf obo:GO_0051050, obo:GO_2000807, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097091 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097091 ] ) ] . obo:GO_2000816 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation." ; oboInOwl:created_by "mah" ; oboInOwl:creation_date "2011-07-11T04:45:06Z" ; oboInOwl:hasExactSynonym "negative regulation of mitotic sister chromatid resolution", "negative regulation of sister chromatid separation during mitosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of chromosome separation during mitosis", "negative regulation of mitotic chromosome separation" ; oboInOwl:id "GO:2000816" ; a owl:Class ; rdfs:label "negative regulation of mitotic sister chromatid separation" ; rdfs:subClassOf obo:GO_0010965, obo:GO_0033048, obo:GO_1905819, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051306 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051306 ] ) ] . obo:GO_2000827 obo:IAO_0000115 "The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion." ; oboInOwl:created_by "bf" ; oboInOwl:creation_date "2011-07-20T01:33:23Z" ; oboInOwl:hasExactSynonym "RNA quality control in mitochondria", "RNA quality control in mitochondrion", "RNA surveillance in mitochondria", "aberrant RNA catabolic process in mitochondria", "aberrant RNA catabolic process in mitochondrion" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2000827" ; a owl:Class ; rdfs:label "mitochondrial RNA surveillance" ; rdfs:subClassOf obo:GO_0000957, obo:GO_0071026 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0071025 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005739 ] ) ] . obo:GO_2001141 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of RNA biosynthetic process." ; oboInOwl:created_by "dph" ; oboInOwl:creation_date "2011-10-17T11:36:25Z" ; oboInOwl:hasExactSynonym "regulation of RNA anabolism", "regulation of RNA biosynthesis", "regulation of RNA formation", "regulation of RNA synthesis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2001141" ; a owl:Class ; rdfs:label "regulation of RNA biosynthetic process" ; rdfs:subClassOf obo:GO_0010556, obo:GO_0051252, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032774 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0032774 ] ) ] . obo:GO_2001222 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of neuron migration." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2011-11-17T10:01:38Z" ; oboInOwl:hasExactSynonym "regulation of neuron chemotaxis", "regulation of neuronal migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of neuron guidance" ; oboInOwl:id "GO:2001222" ; a owl:Class ; rdfs:label "regulation of neuron migration" ; rdfs:subClassOf obo:GO_0030334, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0001764 ] ) ] . obo:GO_2001223 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2011-11-17T10:01:45Z" ; oboInOwl:hasExactSynonym "negative regulation of neuron chemotaxis", "negative regulation of neuronal migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of neuron guidance" ; oboInOwl:id "GO:2001223" ; a owl:Class ; rdfs:label "negative regulation of neuron migration" ; rdfs:subClassOf obo:GO_0030336, obo:GO_2001222, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0001764 ] ) ] . obo:GO_2001224 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of neuron migration." ; oboInOwl:created_by "kmv" ; oboInOwl:creation_date "2011-11-17T10:01:49Z" ; oboInOwl:hasExactSynonym "positive regulation of neuron chemotaxis", "positive regulation of neuronal migration" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of neuron guidance" ; oboInOwl:id "GO:2001224" ; a owl:Class ; rdfs:label "positive regulation of neuron migration" ; rdfs:subClassOf obo:GO_0030335, obo:GO_2001222, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001764 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0001764 ] ) ] . obo:GO_2001228 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of response to gamma radiation." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2011-11-20T04:51:07Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "regulation of response to gamma ray", "regulation of response to gamma-ray photon" ; oboInOwl:id "GO:2001228" ; a owl:Class ; rdfs:label "regulation of response to gamma radiation" ; rdfs:subClassOf obo:GO_0048583, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010332 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0010332 ] ) ] . obo:GO_2001229 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2011-11-20T04:51:14Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of response to gamma ray", "negative regulation of response to gamma-ray photon" ; oboInOwl:id "GO:2001229" ; a owl:Class ; rdfs:label "negative regulation of response to gamma radiation" ; rdfs:subClassOf obo:GO_0048585, obo:GO_2001228, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010332 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0010332 ] ) ] . obo:GO_2001230 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of response to gamma radiation." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2011-11-20T04:51:17Z" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of response to gamma ray", "positive regulation of response to gamma-ray photon" ; oboInOwl:id "GO:2001230" ; a owl:Class ; rdfs:label "positive regulation of response to gamma radiation" ; rdfs:subClassOf obo:GO_0048584, obo:GO_2001228, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010332 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0010332 ] ) ] . obo:GO_2001233 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-24T01:20:49Z" ; oboInOwl:hasExactSynonym "regulation of apoptotic signalling pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2001233" ; a owl:Class ; rdfs:label "regulation of apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_0009966, obo:GO_0042981, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097190 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097190 ] ) ] . obo:GO_2001234 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-24T01:20:54Z" ; oboInOwl:hasExactSynonym "negative regulation of apoptotic signalling pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2001234" ; a owl:Class ; rdfs:label "negative regulation of apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_0009968, obo:GO_0043066, obo:GO_2001233, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097190 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097190 ] ) ] . obo:GO_2001235 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-24T01:20:58Z" ; oboInOwl:hasExactSynonym "positive regulation of apoptotic signalling pathway" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2001235" ; a owl:Class ; rdfs:label "positive regulation of apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_0009967, obo:GO_0043065, obo:GO_2001233, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097190 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097190 ] ) ] . obo:GO_2001242 obo:IAO_0000115 "Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-24T01:35:56Z" ; oboInOwl:hasExactSynonym "regulation of intrinsic apoptotic pathway", "regulation of intrinsic apoptotic signalling pathway", "regulation of mitochondrial-mediated apoptotic pathway" ; oboInOwl:hasNarrowSynonym "regulation of intrinsic apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2001242" ; a owl:Class ; rdfs:label "regulation of intrinsic apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_1902531, obo:GO_2001233, [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097193 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002211 ; owl:someValuesFrom obo:GO_0097193 ] ) ] . obo:GO_2001243 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-24T01:36:03Z" ; oboInOwl:hasExactSynonym "negative regulation of intrinsic apoptotic pathway", "negative regulation of intrinsic apoptotic signalling pathway", "negative regulation of mitochondrial-mediated apoptotic pathway" ; oboInOwl:hasNarrowSynonym "negative regulation of intrinsic apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2001243" ; a owl:Class ; rdfs:label "negative regulation of intrinsic apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_1902532, obo:GO_2001234, obo:GO_2001242, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097193 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0097193 ] ) ] . obo:GO_2001244 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway." ; oboInOwl:created_by "pr" ; oboInOwl:creation_date "2011-11-24T01:36:07Z" ; oboInOwl:hasExactSynonym "positive regulation of intrinsic apoptotic pathway", "positive regulation of intrinsic apoptotic signalling pathway", "positive regulation of mitochondrial-mediated apoptotic pathway" ; oboInOwl:hasNarrowSynonym "positive regulation of intrinsic apoptosis" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:id "GO:2001244" ; a owl:Class ; rdfs:label "positive regulation of intrinsic apoptotic signaling pathway" ; rdfs:subClassOf obo:GO_1902533, obo:GO_2001235, obo:GO_2001242, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097193 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0097193 ] ) ] . obo:GO_2001251 obo:IAO_0000115 "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2011-12-02T02:01:20Z" ; oboInOwl:hasExactSynonym "negative regulation of chromosome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "negative regulation of chromosome organization and biogenesis", "negative regulation of maintenance of genome integrity", "negative regulation of nuclear genome maintenance" ; oboInOwl:id "GO:2001251" ; a owl:Class ; rdfs:label "negative regulation of chromosome organization" ; rdfs:subClassOf obo:GO_0010639, obo:GO_0033044, [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051276 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002212 ; owl:someValuesFrom obo:GO_0051276 ] ) ] . obo:GO_2001252 obo:IAO_0000115 "Any process that activates or increases the frequency, rate or extent of chromosome organization." ; oboInOwl:created_by "yaf" ; oboInOwl:creation_date "2011-12-02T02:01:26Z" ; oboInOwl:hasExactSynonym "positive regulation of chromosome organisation" ; oboInOwl:hasOBONamespace "biological_process" ; oboInOwl:hasRelatedSynonym "positive regulation of chromosome organization and biogenesis", "positive regulation of maintenance of genome integrity", "positive regulation of nuclear genome maintenance" ; oboInOwl:id "GO:2001252" ; a owl:Class ; rdfs:label "positive regulation of chromosome organization" ; rdfs:subClassOf obo:GO_0010638, obo:GO_0033044, [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051276 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:GO_0065007 [ a owl:Restriction ; owl:onProperty obo:RO_0002213 ; owl:someValuesFrom obo:GO_0051276 ] ) ] . obo:IAO_0000002 obo:IAO_0000111 "example to be eventually removed"@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "example to be eventually removed"@en . obo:IAO_0000027 obo:IAO_0000111 "data item"@en ; obo:IAO_0000112 "Data items include counts of things, analyte concentrations, and statistical summaries."@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements."@en ; obo:IAO_0000116 "2/2/2009 Alan and Bjoern discussing FACS run output data. This is a data item because it is about the cell population. Each element records an event and is typically further composed a set of measurment data items that record the fluorescent intensity stimulated by one of the lasers."@en, "2009-03-16: data item deliberatly ambiguous: we merged data set and datum to be one entity, not knowing how to define singular versus plural. So data item is more general than datum."@en, "2009-03-16: removed datum as alternative term as datum specifically refers to singular form, and is thus not an exact synonym."@en, "2014-03-31: See discussion at http://odontomachus.wordpress.com/2014/03/30/aboutness-objects-propositions/", """JAR: datum -- well, this will be very tricky to define, but maybe some information-like stuff that might be put into a computer and that is meant, by someone, to denote and/or to be interpreted by some process... I would include lists, tables, sentences... I think I might defer to Barry, or to Brian Cantwell Smith JAR: A data item is an approximately justified approximately true approximate belief"""@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Chris Stoeckert"@en, "PERSON: Jonathan Rees"@en ; obo:IAO_0000118 "data"@en ; a owl:Class ; rdfs:label "data item"@en ; rdfs:subClassOf obo:IAO_0000030 . obo:IAO_0000030 obo:IAO_0000111 "information content entity"@en ; obo:IAO_0000112 "Examples of information content entites include journal articles, data, graphical layouts, and graphs."@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "A generically dependent continuant that is about some thing."@en ; obo:IAO_0000116 "2014-03-10: The use of \"thing\" is intended to be general enough to include universals and configurations (see https://groups.google.com/d/msg/information-ontology/GBxvYZCk1oc/-L6B5fSBBTQJ)."@en, """information_content_entity 'is_encoded_in' some digital_entity in obi before split (040907). information_content_entity 'is_encoded_in' some physical_document in obi before split (040907). Previous. An information content entity is a non-realizable information entity that 'is encoded in' some digital or physical entity."""@en ; obo:IAO_0000117 "PERSON: Chris Stoeckert"@en ; obo:IAO_0000119 "OBI_0000142"@en ; a owl:Class ; rdfs:label "information content entity"@en ; rdfs:subClassOf obo:BFO_0000031, [ a owl:Restriction ; owl:onProperty obo:IAO_0000136 ; owl:someValuesFrom obo:BFO_0000001 ] . obo:IAO_0000078 obo:IAO_0000111 "curation status specification"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ; obo:IAO_0000116 "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)"@en ; obo:IAO_0000117 "PERSON:Bill Bug"@en ; obo:IAO_0000119 "GROUP:OBI:"@en, "OBI_0000266"@en ; a owl:Class ; rdfs:label "curation status specification"@en ; rdfs:subClassOf obo:IAO_0000102 ; owl:equivalentClass [ a owl:Class ; owl:oneOf (obo:IAO_0000002 obo:IAO_0000120 obo:IAO_0000121 obo:IAO_0000122 obo:IAO_0000123 obo:IAO_0000124 obo:IAO_0000125 obo:IAO_0000423 obo:IAO_0000428 ) ] . obo:IAO_0000102 obo:IAO_0000111 "data about an ontology part"@en ; obo:IAO_0000115 "Data about an ontology part is a data item about a part of an ontology, for example a term"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; a owl:Class ; rdfs:label "data about an ontology part"@en ; rdfs:subClassOf obo:IAO_0000027 . obo:IAO_0000103 obo:IAO_0000111 "failed exploratory term"@en ; obo:IAO_0000115 "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "failed exploratory term"@en . obo:IAO_0000111 a owl:AnnotationProperty . obo:IAO_0000112 a owl:AnnotationProperty . obo:IAO_0000114 a owl:AnnotationProperty . obo:IAO_0000115 obo:IAO_0000111 "definition"@en ; obo:IAO_0000114 obo:IAO_0000122 ; obo:IAO_0000115 "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en ; obo:IAO_0000116 """2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with. """@en ; obo:IAO_0000117 "PERSON:Daniel Schober"@en ; obo:IAO_0000119 "GROUP:OBI:"@en ; a owl:AnnotationProperty ; rdfs:isDefinedBy ; rdfs:label "definition", "definition"@en . obo:IAO_0000116 a owl:AnnotationProperty . obo:IAO_0000117 a owl:AnnotationProperty . obo:IAO_0000118 a owl:AnnotationProperty . obo:IAO_0000119 a owl:AnnotationProperty . obo:IAO_0000120 obo:IAO_0000111 "metadata complete"@en ; obo:IAO_0000115 "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "metadata complete"@en . obo:IAO_0000121 obo:IAO_0000111 "organizational term"@en ; obo:IAO_0000115 "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "organizational term"@en . obo:IAO_0000122 obo:IAO_0000111 "ready for release"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "ready for release"@en . obo:IAO_0000123 obo:IAO_0000111 "metadata incomplete"@en ; obo:IAO_0000115 "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "metadata incomplete"@en . obo:IAO_0000124 obo:IAO_0000111 "uncurated"@en ; obo:IAO_0000115 "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "uncurated"@en . obo:IAO_0000125 obo:IAO_0000111 "pending final vetting"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "pending final vetting"@en . obo:IAO_0000136 obo:IAO_0000112 "This document is about information artifacts and their representations"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "A (currently) primitive relation that relates an information artifact to an entity."@en ; obo:IAO_0000116 """7/6/2009 Alan Ruttenberg. Following discussion with Jonathan Rees, and introduction of \"mentions\" relation. Weaken the is_about relationship to be primitive. We will try to build it back up by elaborating the various subproperties that are more precisely defined. Some currently missing phenomena that should be considered \"about\" are predications - \"The only person who knows the answer is sitting beside me\" , Allegory, Satire, and other literary forms that can be topical without explicitly mentioning the topic."""@en ; obo:IAO_0000117 "person:Alan Ruttenberg"@en ; obo:IAO_0000119 "Smith, Ceusters, Ruttenberg, 2000 years of philosophy"@en ; a owl:ObjectProperty ; rdfs:domain obo:IAO_0000030 ; rdfs:label "is about"@en . obo:IAO_0000225 obo:IAO_0000111 "obsolescence reason specification"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en ; obo:IAO_0000116 "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology."@en ; obo:IAO_0000117 "PERSON: Alan Ruttenberg"@en, "PERSON: Melanie Courtot"@en ; a owl:Class ; rdfs:label "obsolescence reason specification"@en ; rdfs:subClassOf obo:IAO_0000102 ; owl:equivalentClass [ a owl:Class ; owl:oneOf (obo:IAO_0000103 obo:IAO_0000226 obo:IAO_0000227 obo:IAO_0000228 obo:IAO_0000229 obo:OMO_0001000 ) ] . obo:IAO_0000226 obo:IAO_0000111 "placeholder removed"@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "placeholder removed"@en . obo:IAO_0000227 obo:IAO_0000111 "terms merged"@en ; obo:IAO_0000116 "An editor note should explain what were the merged terms and the reason for the merge."@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "terms merged"@en . obo:IAO_0000228 obo:IAO_0000111 "term imported"@en ; obo:IAO_0000116 "This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use."@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "term imported"@en . obo:IAO_0000229 obo:IAO_0000111 "term split"@en ; obo:IAO_0000116 "This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created."@en ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "term split"@en . obo:IAO_0000231 obo:IAO_0000111 "has obsolescence reason"@en ; obo:IAO_0000115 "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en ; obo:IAO_0000117 "PERSON:Alan Ruttenberg"@en, "PERSON:Melanie Courtot"@en ; a owl:AnnotationProperty ; rdfs:label "has obsolescence reason"@en . obo:IAO_0000232 a owl:AnnotationProperty . obo:IAO_0000233 a owl:AnnotationProperty . obo:IAO_0000234 a owl:AnnotationProperty . obo:IAO_0000409 obo:IAO_0000111 "denotator type"@en ; obo:IAO_0000112 "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities."@en ; obo:IAO_0000115 "A denotator type indicates how a term should be interpreted from an ontological perspective."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; obo:IAO_0000119 "Barry Smith, Werner Ceusters"@en ; a owl:Class ; rdfs:label "denotator type"@en ; rdfs:subClassOf obo:IAO_0000102 ; owl:equivalentClass [ a owl:Class ; owl:oneOf (obo:IAO_0000410 obo:IAO_0000420 obo:IAO_0000421 ) ] . obo:IAO_0000410 obo:IAO_0000111 "universal"@en ; obo:IAO_0000116 "Hard to give a definition for. Intuitively a \"natural kind\" rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; obo:IAO_0000119 "A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf"@en ; a obo:IAO_0000409, owl:NamedIndividual ; rdfs:label "universal"@en . obo:IAO_0000412 a owl:AnnotationProperty . obo:IAO_0000420 obo:IAO_0000111 "defined class"@en ; obo:IAO_0000115 "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en ; obo:IAO_0000116 "\"definitions\", in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; a obo:IAO_0000409, owl:NamedIndividual ; rdfs:label "defined class"@en . obo:IAO_0000421 obo:IAO_0000111 "named class expression"@en ; obo:IAO_0000115 "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en ; obo:IAO_0000116 "named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions"@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; a obo:IAO_0000409, owl:NamedIndividual ; rdfs:label "named class expression"@en . obo:IAO_0000423 obo:IAO_0000111 "to be replaced with external ontology term"@en ; obo:IAO_0000115 "Terms with this status should eventually replaced with a term from another ontology."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; obo:IAO_0000119 "group:OBI"@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "to be replaced with external ontology term"@en . obo:IAO_0000424 a owl:AnnotationProperty . obo:IAO_0000428 obo:IAO_0000111 "requires discussion"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en ; obo:IAO_0000117 "Alan Ruttenberg"@en ; obo:IAO_0000119 "group:OBI"@en ; a obo:IAO_0000078, owl:NamedIndividual ; rdfs:label "requires discussion"@en . obo:IAO_0000589 a owl:AnnotationProperty . obo:IAO_0000600 a owl:AnnotationProperty . obo:IAO_0000601 a owl:AnnotationProperty . obo:IAO_0000602 a owl:AnnotationProperty . obo:IAO_0000700 obo:IAO_0000111 "has ontology root term"@en ; obo:IAO_0000115 "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en ; obo:IAO_0000117 "Nicolas Matentzoglu"@en ; oboInOwl:hasDbXref "IAO:0000700" ; oboInOwl:hasOBONamespace "external" ; oboInOwl:id "has_ontology_root_term" ; oboInOwl:is_class_level true ; oboInOwl:is_metadata_tag true ; oboInOwl:shorthand "has_ontology_root_term" ; a owl:AnnotationProperty ; rdfs:label "has ontology root term", "has ontology root term"@en, "preferred_root" . obo:IAO_0010000 a owl:AnnotationProperty . obo:IAO_0100001 obo:IAO_0000111 "term replaced by"@en ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en ; obo:IAO_0000117 "Person:Alan Ruttenberg"@en ; obo:IAO_0000119 "Person:Alan Ruttenberg"@en ; a owl:AnnotationProperty ; rdfs:comment "Add as annotation triples in the granting ontology"@en ; rdfs:label "term replaced by", "term replaced by"@en . obo:NCBITaxon_131567 a owl:Class . obo:NCBITaxon_33208 a owl:Class . obo:NCBITaxon_6237 a owl:Class . obo:OMO_0001000 obo:IAO_0000115 "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en ; obo:IAO_0000116 "This obsolesence reason should be used conservatively. Typical valid examples are: un-necessary grouping classes in disease ontologies, a phenotype term added on the assumption it was a disease."@en ; obo:IAO_0000117 ; obo:IAO_0000233 "https://github.com/information-artifact-ontology/ontology-metadata/issues/77" ; obo:IAO_0000234 "https://orcid.org/0000-0001-5208-3432" ; a obo:IAO_0000225, owl:NamedIndividual ; rdfs:label "out of scope" . obo:PATO_0000001 obo:IAO_0000115 "A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities" ; oboInOwl:hasAlternativeId "PATO:0000072" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000001" ; a owl:Class ; rdfs:label "quality" ; rdfs:subClassOf obo:BFO_0000020 . obo:PATO_0000004 obo:IAO_0000115 "A quality of inhering in a bearer by virtue of the bearer's disposition to move freely." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000004" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim, pato:scalar_slim ; a owl:Class ; rdfs:comment "Should be defined using translocation." ; rdfs:label "mobility" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0000008 obo:IAO_0000115 "A physical quality inhering in a bearer by virtue of the bearer's scalar absolute value of the rate of change of the bearer's position." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "velocity" ; oboInOwl:id "PATO:0000008" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "speed" ; rdfs:subClassOf obo:PATO_0001906 . obo:PATO_0000014 obo:IAO_0000115 "A composite chromatic quality composed of hue, saturation and intensity parts." ; oboInOwl:hasAlternativeId "PATO:0000020" ; oboInOwl:hasExactSynonym "colour", "relative color" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000014" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "color" ; rdfs:subClassOf obo:PATO_0000051, obo:PATO_0001300 . obo:PATO_0000016 obo:IAO_0000115 "A scalar optical property that is the intensity, value or amount of perceived light." ; oboInOwl:hasExactSynonym "color intensity", "color lightness", "color value" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000016" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:comment "Color brightness refers to the intensity, lightness or value of the light present. Think of this as a dimmer switch." ; rdfs:label "color brightness" ; rdfs:subClassOf obo:PATO_0001300 . obo:PATO_0000017 obo:IAO_0000115 "A scalar chromatic property that is the degree of purity of perceived light." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000017" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:comment "Color saturation refers to the amount of white light or gray paint mixed in with the hue (single wavelength) and is a measure of color purity." ; rdfs:label "color saturation" ; rdfs:subClassOf obo:PATO_0001301 . obo:PATO_0000018 obo:IAO_0000115 "A luminous flux quality inhering in a bearer by virtue of the bearer's emitting longer wavelength light following the absorption of shorter wavelength radiation; fluorescence is common with aromatic compounds with several rings joined together." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000018" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "fluorescence" ; rdfs:subClassOf obo:PATO_0001296 . obo:PATO_0000025 obo:IAO_0000115 "A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts." ; oboInOwl:hasAlternativeId "PATO:0002015" ; oboInOwl:hasExactSynonym "composed of", "compositionality", "content", "structure, composition" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000025" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:comment "For example calcium composition (which may inhere in bone), haemoglobin composition (which may inhere in blood)." ; rdfs:label "composition" ; rdfs:subClassOf obo:PATO_0000141 . obo:PATO_0000033 obo:IAO_0000115 "A quality inhering in a substance by virtue of the amount of the bearer's there is mixed with another substance." ; oboInOwl:hasExactSynonym "concentration" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000033" ; oboInOwl:inSubset pato:attribute_slim, pato:relational_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "concentration of" ; rdfs:subClassOf obo:PATO_0002182 . obo:PATO_0000040 obo:IAO_0000115 "A quality that is the extent of space between two entities." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000040" ; oboInOwl:inSubset pato:attribute_slim, pato:relational_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "distance" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0000044 obo:IAO_0000115 "A physical quality which inheres in a bearer by virtue of the number of the bearer's repetitive actions in a particular time." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000044" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "frequency" ; rdfs:subClassOf obo:PATO_0050000 . obo:PATO_0000047 obo:IAO_0000115 "An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000047" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "biological sex" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0000050 obo:IAO_0000115 "A time quality inhering in a bearer by virtue of the bearer's expected maximum age." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000050" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "life span" ; rdfs:subClassOf obo:PATO_0000165 . obo:PATO_0000051 obo:IAO_0000111 "morphology" ; obo:IAO_0000115 "A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure." ; obo:IAO_0000412 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000051" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "morphology" ; rdfs:subClassOf obo:PATO_0001241 . obo:PATO_0000052 obo:IAO_0000115 "A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc)." ; oboInOwl:hasAlternativeId "PATO:0001647" ; oboInOwl:hasExactSynonym "relational shape quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000052" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:comment "Shapes are invariant on size transformations. Shapes can be subdivided into 2D and 3D shapes, We can also make a distinction between shapes of complete self-connected objects, and shapes of parts of objects." ; rdfs:label "shape" ; rdfs:subClassOf obo:PATO_0000051 . obo:PATO_0000057 obo:IAO_0000115 "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence." ; oboInOwl:hasAlternativeId "PATO:0000156", "PATO:0000158" ; oboInOwl:hasBroadSynonym "temporal" ; oboInOwl:hasExactSynonym "incidence" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000057" ; oboInOwl:inSubset pato:attribute_slim, pato:hpo_slim ; a owl:Class ; rdfs:label "occurrence" ; rdfs:subClassOf obo:PATO_0002323 . obo:PATO_0000060 obo:IAO_0000115 "A spatial quality inhering in a bearer by virtue of the bearer's exhibiting repetition of placement of its parts." ; oboInOwl:hasAlternativeId "PATO:0000132", "PATO:0001565" ; oboInOwl:hasExactSynonym "distribution" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "pattern" ; oboInOwl:id "PATO:0000060" ; oboInOwl:inSubset pato:attribute_slim, pato:hpo_slim ; a owl:Class ; rdfs:label "spatial pattern" ; rdfs:subClassOf obo:PATO_0000051 . obo:PATO_0000068 oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000068" ; a owl:Class ; rdfs:comment "TODO: define this or obsolete it and move children somewhere else." ; rdfs:label "qualitative" ; rdfs:subClassOf obo:PATO_0000001 . obo:PATO_0000069 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000069" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "deviation (from_normal)" ; rdfs:subClassOf obo:PATO_0000068 . obo:PATO_0000070 obo:IAO_0000115 "The number of entities of this type that are part of the whole organism." ; oboInOwl:hasAlternativeId "PATO:0000053", "PATO:0000071", "PATO:0001169", "PATO:0001226" ; oboInOwl:hasExactSynonym "presence or absence in organism", "quantitative" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "count in organism", "number", "presence" ; oboInOwl:id "PATO:0000070" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:comment "This term was originally named \"presence\". It has been renamed to reduce ambiguity. Consider annotating with the reciprocal relation,PATO:0001555, has_number_of. For example, rather than E=fin ray Q=count in organism C=10, say E=organism Q=has number of E2= fin ray C=10." ; rdfs:label "amount" ; rdfs:subClassOf obo:PATO_0000068, [ a owl:Restriction ; owl:onProperty obo:RO_0015012 ; owl:someValuesFrom obo:PATO_0001555 ] . obo:PATO_0000077 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the whether the bearer's disposition to react to a stimulus or an agent." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "reactivity", "response", "responsivity" ; oboInOwl:id "PATO:0000077" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim, pato:relational_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "response to" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0000078 obo:IAO_0000115 "A quality of a single process inhering in a bearer by virtue of the bearer's movement or variation characterized by the regular recurrence or alternation of different quantities or conditions." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000078" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "rhythm quality" ; rdfs:subClassOf obo:PATO_0002323 . obo:PATO_0000080 obo:IAO_0000115 "A physical quality of a process inhering in a bearer by virtue of the size of the bearer's maximum displacement from the 'normal' position, when periodic motion is taking place." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000080" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "amplitude" ; rdfs:subClassOf obo:PATO_0002062 . obo:PATO_0000082 obo:IAO_0000115 "A rhythm quality inhering in a bearer by virtue of the repetitiveness of bearer's rhythm." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000082" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "persistence" ; rdfs:subClassOf obo:PATO_0000078 . obo:PATO_0000085 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's disposition to detect or perceive external stimulation." ; oboInOwl:hasExactSynonym "sensitivity" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000085" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim, pato:relational_slim ; a owl:Class ; rdfs:label "sensitivity toward" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0000117 obo:IAO_0000115 "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000117" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "size" ; rdfs:subClassOf obo:PATO_0000051 . obo:PATO_0000119 obo:IAO_0000115 "A 1-D extent quality inhering in a bearer by virtue of the bearer's vertical dimension of extension." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000119" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "height" ; rdfs:subClassOf obo:PATO_0001708 . obo:PATO_0000122 obo:IAO_0000115 "A 1-D extent quality which is equal to the distance between two points." ; pato:seeAlso "https://github.com/pato-ontology/pato/issues/337" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000122" ; oboInOwl:inSubset pato:attribute_slim, pato:mpath_slim, pato:scalar_slim ; a owl:Class ; rdfs:comment "Length often refers to the longer or longest dimension of an object, however, this is not always true. See https://github.com/pato-ontology/pato/issues/337 for full discussion." ; rdfs:label "length" ; rdfs:subClassOf obo:PATO_0001708 . obo:PATO_0000133 obo:IAO_0000115 "A spatial quality inhering in a bearer by virtue of the bearer's placement which is defined by the angle between the bearer and an axis, or the angle between the bearer and another object." ; oboInOwl:hasAlternativeId "PATO:0000137" ; oboInOwl:hasExactSynonym "angular placement" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "amount of rotation", "angle", "angular magnitude", "plane angle" ; oboInOwl:id "PATO:0000133" ; oboInOwl:inSubset pato:attribute_slim, pato:relational_slim ; a owl:Class ; rdfs:label "orientation" ; rdfs:subClassOf obo:PATO_0000140 . obo:PATO_0000136 obo:IAO_0000115 "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000136" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "closure" ; rdfs:subClassOf obo:PATO_0000051 . obo:PATO_0000140 obo:IAO_0000115 "A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity." ; oboInOwl:hasAlternativeId "PATO:0001032", "PATO:0001631" ; oboInOwl:hasExactSynonym "location", "placement", "relational spatial quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000140" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "position" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0000141 obo:IAO_0000115 "A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form." ; oboInOwl:hasAlternativeId "PATO:0001452" ; oboInOwl:hasBroadSynonym "conformation" ; oboInOwl:hasExactSynonym "relational structural quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000141" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "structure" ; rdfs:subClassOf obo:PATO_0000051 . obo:PATO_0000150 obo:IAO_0000115 "A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000150" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "texture" ; rdfs:subClassOf obo:PATO_0000051 . obo:PATO_0000161 obo:IAO_0000115 "A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000161" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "rate" ; rdfs:subClassOf obo:PATO_0002062 . obo:PATO_0000165 obo:IAO_0000115 "A quality in which events occur in sequence." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000165" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "time" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0000169 obo:IAO_0000115 "An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000169" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim ; a owl:Class ; rdfs:label "viability" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0000186 obo:IAO_0000115 "An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation." ; oboInOwl:hasAlternativeId "PATO:0001722" ; oboInOwl:hasExactSynonym "behavioural quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000186" ; a owl:Class ; rdfs:label "behavioral quality" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0000188 obo:IAO_0000115 "A behavioral quality inhering in a bearer by virtue of the bearer's having or lacking skillful and effective interaction of movement." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000188" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "coordination" ; rdfs:subClassOf obo:PATO_0000186 . obo:PATO_0000274 obo:IAO_0000115 "A reproductive quality inhering in a bearer by virtue of the bearer's initiating, sustaining, or supporting reproduction." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000274" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim ; a owl:Class ; rdfs:label "fertility" ; rdfs:subClassOf obo:PATO_0001434 . obo:PATO_0000276 obo:IAO_0000115 "A reproductive quality inhering in the young of an animal by virtue of their number." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "litter size" ; oboInOwl:id "PATO:0000276" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "brood size" ; rdfs:subClassOf obo:PATO_0001496 . obo:PATO_0000279 obo:IAO_0000115 "A fertility quality of inhering in a male by virtue of the bearer's disposition to initiate, sustain, or support reproduction." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000279" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim ; a owl:Class ; rdfs:label "male fertility" ; rdfs:subClassOf obo:PATO_0000274 . obo:PATO_0000297 obo:IAO_0000115 "A quality of a process which ends earlier than the natural end time or reference process." ; oboInOwl:hasAlternativeId "PATO:0001508" ; oboInOwl:hasExactSynonym "abolished" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "incomplete" ; oboInOwl:id "PATO:0000297" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:comment "TODO: the definition is incorrect. See absent." ; rdfs:label "arrested" ; rdfs:subClassOf obo:PATO_0002052, obo:PATO_0002324 . obo:PATO_0000300 obo:IAO_0000115 "A mobility quality inhering in a bearer by virtue of the bearer's being incapable to move freely." ; obo:RO_0002604 obo:PATO_0000299 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "fixed" ; oboInOwl:id "PATO:0000300" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "immobile" ; rdfs:subClassOf obo:PATO_0000004 . obo:PATO_0000303 obo:IAO_0000115 "A speed which is relatively high." ; obo:RO_0002604 obo:PATO_0000304 ; oboInOwl:hasExactSynonym "high speed" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "fast speed" ; oboInOwl:id "PATO:0000303" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased speed" ; rdfs:subClassOf obo:PATO_0000008, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000008 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000304 obo:IAO_0000115 "A speed which is relatively low." ; obo:RO_0002604 obo:PATO_0000303 ; oboInOwl:hasExactSynonym "slow", "slow speed" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000304" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased speed" ; rdfs:subClassOf obo:PATO_0000008, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000008 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000327 obo:IAO_0000115 "A color brightness which is relatively low." ; obo:RO_0002604 obo:PATO_0000665 ; oboInOwl:hasExactSynonym "dark" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000327" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "low brightness" ; rdfs:subClassOf obo:PATO_0000016 . obo:PATO_0000328 obo:IAO_0000115 "A color saturation which is of low purity." ; obo:RO_0002604 obo:PATO_0001229 ; oboInOwl:hasExactSynonym "pale" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "dull" ; oboInOwl:id "PATO:0000328" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "low saturation" ; rdfs:subClassOf obo:PATO_0000017 . obo:PATO_0000330 obo:IAO_0000115 "A spatial pattern inhering in a bearer by virtue of the bearer's magnitude of or the relationships between its repeated parts lack consistency." ; obo:RO_0002604 obo:PATO_0000440 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000330" ; oboInOwl:inSubset pato:cell_quality, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "irregular spatial pattern" ; rdfs:subClassOf obo:PATO_0000060 . obo:PATO_0000374 obo:IAO_0000115 "A distance which is greater relative to the normal or average." ; obo:RO_0002604 obo:PATO_0000375 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "long distance" ; oboInOwl:id "PATO:0000374" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased distance" ; rdfs:subClassOf obo:PATO_0000040, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000040 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000375 obo:IAO_0000115 "A distance which is lesser relative to the normal or average." ; obo:RO_0002604 obo:PATO_0000374 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "short distance" ; oboInOwl:id "PATO:0000375" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased distance" ; rdfs:subClassOf obo:PATO_0000040, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000040 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000380 obo:IAO_0000115 "A frequency which is relatively high." ; obo:RO_0002604 obo:PATO_0000381 ; oboInOwl:hasExactSynonym "high frequency" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "frequent" ; oboInOwl:id "PATO:0000380" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased frequency" ; rdfs:subClassOf obo:PATO_0000044, obo:PATO_0055003 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000044 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000381 obo:IAO_0000115 "A frequency which is relatively low." ; obo:RO_0002604 obo:PATO_0000380 ; oboInOwl:hasExactSynonym "low frequency" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "infrequent" ; oboInOwl:id "PATO:0000381" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased frequency" ; rdfs:subClassOf obo:PATO_0000044, obo:PATO_0055004 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000044 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000384 obo:IAO_0000115 "A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000384" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "male" ; rdfs:subClassOf obo:PATO_0001894 . obo:PATO_0000402 obo:IAO_0000115 "A branchiness quality inhering in a bearer by virtue of the bearer's having branches." ; obo:RO_0002604 obo:PATO_0000414 ; oboInOwl:hasExactSynonym "ramified", "ramiform" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000402" ; oboInOwl:inSubset pato:cell_quality, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "branched" ; rdfs:subClassOf obo:PATO_0002009 . obo:PATO_0000404 obo:IAO_0000115 "A shape quality inhering in a bearer by virtue of the bearer's being curled or wound (especially in concentric rings or spirals)." ; obo:RO_0002604 obo:PATO_0000415 ; oboInOwl:hasAlternativeId "PATO:0001363" ; oboInOwl:hasExactSynonym "spiral" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "helical", "helicoid", "helicoidal", "helix-shaped" ; oboInOwl:id "PATO:0000404" ; oboInOwl:inSubset pato:cell_quality, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "coiled" ; rdfs:subClassOf obo:PATO_0001794 . obo:PATO_0000411 obo:IAO_0000115 "A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "round", "rounded" ; oboInOwl:id "PATO:0000411" ; oboInOwl:inSubset pato:cell_quality, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "circular" ; rdfs:subClassOf obo:PATO_0000947 . obo:PATO_0000440 obo:IAO_0000115 "A pattern quality inhering in a bearer by virtue of the bearer's having a repeatable or predictable placement." ; obo:RO_0002604 obo:PATO_0000330 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000440" ; oboInOwl:inSubset pato:mpath_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "regular spatial pattern" ; rdfs:subClassOf obo:PATO_0000060 . obo:PATO_0000460 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's deviation from normal or average." ; obo:RO_0002604 obo:PATO_0000461 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "aberrant", "atypia", "atypical", "defective" ; oboInOwl:id "PATO:0000460" ; oboInOwl:inSubset pato:abnormal_slim, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "abnormal" ; rdfs:subClassOf obo:PATO_0000069 . obo:PATO_0000461 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average." ; obo:RO_0002604 obo:PATO_0000460 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "average" ; oboInOwl:id "PATO:0000461" ; oboInOwl:inSubset pato:abnormal_slim, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "normal" ; rdfs:subClassOf obo:PATO_0000068 . obo:PATO_0000462 obo:IAO_0000115 "A quality denoting the lack of an entity." ; obo:RO_0002604 obo:PATO_0000467 ; oboInOwl:hasAlternativeId "PATO:0001996" ; oboInOwl:hasExactSynonym "absence", "absent from organism" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000462" ; oboInOwl:inSubset pato:absent_slim, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:comment """We recommend using the new absent terms (physical absence, absent anatomical entity, or absent process) instead of this class. This is a legacy term and will ultimately be obsoleted. See https://github.com/pato-ontology/pato/issues/331.""" ; rdfs:label "absent" ; rdfs:subClassOf obo:PATO_0000070, [ a owl:Restriction ; owl:onProperty obo:RO_0015012 ; owl:someValuesFrom obo:PATO_0001558 ], [ a owl:Restriction ; owl:onProperty obo:RO_0015012 ; owl:someValuesFrom obo:PATO_0002000 ] ; owl:disjointWith obo:PATO_0000467 . obo:PATO_0000467 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's existence." ; obo:RO_0002604 obo:PATO_0000462 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "present in organism" ; oboInOwl:id "PATO:0000467" ; oboInOwl:inSubset pato:absent_slim, pato:value_slim ; a owl:Class ; rdfs:label "present" ; rdfs:subClassOf obo:PATO_0000070 . obo:PATO_0000470 obo:IAO_0000115 "An amount which is relatively high." ; obo:RO_0002604 obo:PATO_0001997 ; oboInOwl:hasAlternativeId "PATO:0000420", "PATO:0000650" ; oboInOwl:hasExactSynonym "increased number", "present in greater numbers in organism", "supernumerary" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "accessory", "increased" ; oboInOwl:id "PATO:0000470" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased amount" ; rdfs:subClassOf obo:PATO_0000467, obo:PATO_0002300 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000487 obo:IAO_0000115 "A response quality inhering in a bearer by virtue of the bearer's disposition to react to a stimulus or an agent." ; obo:RO_0002604 obo:PATO_0000488 ; oboInOwl:hasExactSynonym "responsive" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000487" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "responsive to" ; rdfs:subClassOf obo:PATO_0000077 ; owl:disjointWith obo:PATO_0000488 . obo:PATO_0000488 obo:IAO_0000115 "A response quality inhering in a bearer by virtue of the bearer's lack of reaction to a stimulus or an agent." ; obo:RO_0002604 obo:PATO_0000487 ; oboInOwl:hasExactSynonym "unresponsive" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000488" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "unresponsive to" ; rdfs:subClassOf obo:PATO_0000077 . obo:PATO_0000498 obo:IAO_0000115 "A duration quality of a process which is relatively high." ; obo:RO_0002604 obo:PATO_0000499 ; oboInOwl:hasAlternativeId "PATO:0000715" ; oboInOwl:hasExactSynonym "high time", "increased period", "increased time" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "chronic", "prolonged period", "slow time" ; oboInOwl:id "PATO:0000498" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased duration" ; rdfs:subClassOf obo:PATO_0001309, obo:PATO_0002304 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001309 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000499 obo:IAO_0000115 "A duration quality of a process which is relatively low." ; obo:RO_0002604 obo:PATO_0000498 ; oboInOwl:hasAlternativeId "PATO:0000716" ; oboInOwl:hasExactSynonym "decreased period", "decreased time", "low period", "shortened period" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "fast time" ; oboInOwl:id "PATO:0000499" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased duration" ; rdfs:subClassOf obo:PATO_0001309, obo:PATO_0002302 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001309 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000502 obo:IAO_0000115 "A quality of a process which starts later than the natural start time or the reference process." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "late" ; oboInOwl:id "PATO:0000502" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "delayed" ; rdfs:subClassOf obo:PATO_0002325 . obo:PATO_0000513 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's lacking sensitivity toward an external stimulus." ; obo:RO_0002604 obo:PATO_0000516 ; oboInOwl:hasExactSynonym "insensitive" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "resistant" ; oboInOwl:id "PATO:0000513" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "insensitive toward" ; rdfs:subClassOf obo:PATO_0000085 . obo:PATO_0000516 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's having sensitivity toward an external stimulus." ; obo:RO_0002604 obo:PATO_0000513 ; oboInOwl:hasExactSynonym "sensitive" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000516" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "sensitive toward" ; rdfs:subClassOf obo:PATO_0000085 . obo:PATO_0000569 obo:IAO_0000115 "A height which is relatively low." ; obo:RO_0002604 obo:PATO_0000570 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "short" ; oboInOwl:id "PATO:0000569" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased height" ; rdfs:subClassOf obo:PATO_0000119, obo:PATO_0000587 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000119 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000570 obo:IAO_0000115 "A height which is relatively high." ; obo:RO_0002604 obo:PATO_0000569 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "tall" ; oboInOwl:id "PATO:0000570" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased height" ; rdfs:subClassOf obo:PATO_0000119, obo:PATO_0000586 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000119 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000573 obo:IAO_0000115 "A length quality which is relatively large." ; obo:RO_0002604 obo:PATO_0000574 ; oboInOwl:hasExactSynonym "long" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000573" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased length" ; rdfs:subClassOf obo:PATO_0000122, obo:PATO_0000586 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000122 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000574 obo:IAO_0000115 "A length quality which is relatively small." ; obo:RO_0002604 obo:PATO_0000573 ; oboInOwl:hasExactSynonym "short" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "shortened", "stubby" ; oboInOwl:id "PATO:0000574" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased length" ; rdfs:subClassOf obo:PATO_0000122, obo:PATO_0000587 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000122 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000584 obo:IAO_0000115 "An increased size quality inhering in a bearer by virtue of the bearer's exhibiting enlargement of a cell or constituent group of cells (for example, organ)." ; obo:RO_0002604 obo:PATO_0000585 ; oboInOwl:hasNarrowSynonym "hypertrophy" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000584" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "hypertrophic" ; rdfs:subClassOf obo:PATO_0000595 . obo:PATO_0000585 obo:IAO_0000115 "A decreased size quality inhering in a bearer by virtue of the bearer's exhibiting reduced size of a cell or constituent group of cells (for example, organ)." ; obo:RO_0002604 obo:PATO_0000584 ; oboInOwl:hasAlternativeId "PATO:0000412" ; oboInOwl:hasExactSynonym "shrunken" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000585" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "hypotrophic" ; rdfs:subClassOf obo:PATO_0000596 . obo:PATO_0000586 obo:IAO_0000115 "A size quality which is relatively high." ; obo:RO_0002604 obo:PATO_0000587 ; oboInOwl:hasAlternativeId "PATO:0001202" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "big", "enlarged", "expanded", "great", "large" ; oboInOwl:id "PATO:0000586" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased size" ; rdfs:subClassOf obo:PATO_0000117, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000117 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000587 obo:IAO_0000115 "A size quality which is relatively low." ; obo:RO_0002604 obo:PATO_0000586 ; oboInOwl:hasNarrowSynonym "hypoplasia", "underdeveloped" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "reduced", "small", "tiny" ; oboInOwl:id "PATO:0000587" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased size" ; rdfs:subClassOf obo:PATO_0000117, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000117 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000591 obo:IAO_0000115 "A thickness which is relatively high." ; obo:RO_0002604 obo:PATO_0000592 ; oboInOwl:hasExactSynonym "high thickness", "stout", "thickened" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "thick" ; oboInOwl:id "PATO:0000591" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased thickness" ; rdfs:subClassOf obo:PATO_0000586, obo:PATO_0000915 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000915 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000592 obo:IAO_0000115 "A thickness which is relatively low." ; obo:RO_0002604 obo:PATO_0000591 ; oboInOwl:hasExactSynonym "low thickness" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "slender", "thin" ; oboInOwl:id "PATO:0000592" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased thickness" ; rdfs:subClassOf obo:PATO_0000587, obo:PATO_0000915 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000915 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000595 obo:IAO_0000115 "A volume which is relatively high." ; obo:RO_0002604 obo:PATO_0000596 ; oboInOwl:hasExactSynonym "high volume" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "large volume" ; oboInOwl:id "PATO:0000595" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased volume" ; rdfs:subClassOf obo:PATO_0000586, obo:PATO_0000918 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000918 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000596 obo:IAO_0000115 "A volume which is relatively low." ; obo:RO_0002604 obo:PATO_0000595 ; oboInOwl:hasExactSynonym "low volume" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "small volume" ; oboInOwl:id "PATO:0000596" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased volume" ; rdfs:subClassOf obo:PATO_0000587, obo:PATO_0000918 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000918 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000608 obo:IAO_0000115 "A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view." ; obo:RO_0002604 obo:PATO_0000610 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "blocked" ; oboInOwl:id "PATO:0000608" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "closed" ; rdfs:subClassOf obo:PATO_0000136 . obo:PATO_0000614 obo:IAO_0000115 "A pattern where all the repeated elements are oriented in the same direction." ; obo:RO_0002604 obo:PATO_0000613 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000614" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "oriented" ; rdfs:subClassOf obo:PATO_0000440 . obo:PATO_0000616 obo:IAO_0000115 "A symmetry quality inhering in a bearer by virtue of the bearer's lacking symmetry." ; oboInOwl:hasExactSynonym "asymmetric", "asymmetry" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000616" ; oboInOwl:inSubset pato:cell_quality, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "asymmetrical" ; rdfs:subClassOf obo:PATO_0000965 . obo:PATO_0000617 obo:IAO_0000115 "A shape quality inhering in a bearer by virtue of the bearer's having one or more angle(s) in its length." ; oboInOwl:hasExactSynonym "angled", "flexed" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000617" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "bent" ; rdfs:subClassOf obo:PATO_0000052 . obo:PATO_0000625 obo:IAO_0000115 "An oriented quality inhering in a bearer by virtue of the bearer's being reversed in position, order, or condition." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "backward", "reversed" ; oboInOwl:id "PATO:0000625" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "inverted" ; rdfs:subClassOf obo:PATO_0000614 . obo:PATO_0000628 obo:IAO_0000115 "A positional quality inhering in a bearer by virtue the bearer's being changed in abnormal position." ; oboInOwl:hasAlternativeId "PATO:0000621" ; oboInOwl:hasExactSynonym "ectopic", "mislocalized" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000628" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "mislocalised" ; rdfs:subClassOf obo:PATO_0002181 . obo:PATO_0000639 obo:IAO_0000115 "A structural quality inhering in a bearer whose structure deteriorates or is lost over time due to an active pathological process." ; obo:RO_0002604 obo:PATO_0002038 ; oboInOwl:hasNarrowSynonym "degeneration" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000639" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "degenerate" ; rdfs:subClassOf obo:PATO_0002037, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:PATO_0000585 ] . obo:PATO_0000642 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of the bearer's being merged with another entity." ; obo:RO_0002604 obo:PATO_0000651 ; oboInOwl:hasExactSynonym "fused", "fused to" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "coalesced", "joined with", "merged with" ; oboInOwl:id "PATO:0000642" ; oboInOwl:inSubset pato:mpath_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "fused with" ; rdfs:subClassOf obo:PATO_0000141 . obo:PATO_0000648 obo:IAO_0000115 "A morphological quality inhering in a bearer by virtue of the bearer's being blocked or filled with obstacles or an obstacle." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000648" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "obstructed" ; rdfs:subClassOf obo:PATO_0000608 . obo:PATO_0000688 obo:IAO_0000115 "A quality of a single process inhering in a bearer by virtue of the bearer's not occurring or existing at the same time or having the same period or phase." ; obo:RO_0002604 obo:PATO_0000695 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000688" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "asynchronous" ; rdfs:subClassOf obo:PATO_0000057 . obo:PATO_0000689 obo:IAO_0000115 "A quality of a single process inhering in a bearer by virtue of the bearer's being uninterrupted in time, sequence, substance, or extent." ; obo:RO_0002604 obo:PATO_0000690 ; oboInOwl:hasAlternativeId "PATO:0000429" ; oboInOwl:hasExactSynonym "uninterrupted" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000689" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "continuous" ; rdfs:subClassOf obo:PATO_0000057 . obo:PATO_0000694 obo:IAO_0000115 "A quality of a process which starts earlier than the natural start time or the reference process." ; oboInOwl:hasAlternativeId "PATO:0000691", "PATO:0002086" ; oboInOwl:hasExactSynonym "advanced" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "early", "precocious" ; oboInOwl:id "PATO:0000694" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "premature" ; rdfs:subClassOf obo:PATO_0002325 . obo:PATO_0000718 obo:IAO_0000115 "A viability quality inhering in a population by virtue of the bearer's long term survival inability." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000718" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "lethal (sensu genetics)" ; rdfs:subClassOf obo:PATO_0000169 . obo:PATO_0000760 obo:IAO_0000115 "A behavioral quality of a process inhering in a bearer by virtue of the bearer's exhibiting increased activity." ; obo:RO_0002604 obo:PATO_0000761 ; oboInOwl:hasExactSynonym "hyperactive" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000760" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased behavioural activity" ; rdfs:subClassOf obo:PATO_0001707, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001707 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000761 obo:IAO_0000115 "A behavioral quality of a process inhering in a bearer by virtue of the bearer's exhibiting reduced activity." ; obo:RO_0002604 obo:PATO_0000760 ; oboInOwl:hasExactSynonym "hypoactive" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000761" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased behavioural activity" ; rdfs:subClassOf obo:PATO_0001707, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001707 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000763 obo:IAO_0000115 "A behavioral quality inhering in a bearer by virtue of the bearer's being affected by loss of the ability to move a body part." ; oboInOwl:hasNarrowSynonym "palsy" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000763" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "paralysed" ; rdfs:subClassOf obo:PATO_0002076 . obo:PATO_0000770 obo:IAO_0000115 "A coordination quality of inhering in a bearer by virtue of the bearer's lacking skillful and effective interaction of movement." ; obo:RO_0002604 obo:PATO_0000769 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000770" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "uncoordinated" ; rdfs:subClassOf obo:PATO_0000188 . obo:PATO_0000911 obo:IAO_0000115 "A rate which is relatively low." ; obo:RO_0002604 obo:PATO_0000912 ; oboInOwl:hasExactSynonym "slow rate" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000911" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased rate" ; rdfs:subClassOf obo:PATO_0000161, obo:PATO_0002302 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000161 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000912 obo:IAO_0000115 "A rate which is relatively high." ; obo:RO_0002604 obo:PATO_0000911 ; oboInOwl:hasExactSynonym "fast rate", "high rate" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000912" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased rate" ; rdfs:subClassOf obo:PATO_0000161, obo:PATO_0002304 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000161 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0000915 obo:IAO_0000115 "A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width." ; pato:seeAlso "https://github.com/pato-ontology/pato/issues/337" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000915" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:comment "Thickness often refers to the smallest 1-D extent compared to the other two orthogonal dimensions, however, this is not always true. See https://github.com/pato-ontology/pato/issues/337 for full discussion." ; rdfs:label "thickness" ; rdfs:subClassOf obo:PATO_0001708 . obo:PATO_0000918 obo:IAO_0000115 "A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000918" ; oboInOwl:inSubset pato:attribute_slim, pato:mpath_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "volume" ; rdfs:subClassOf obo:PATO_0001710 . obo:PATO_0000937 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of the bearer's lacking organisation." ; obo:RO_0002604 obo:PATO_0000938 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000937" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "disorganized" ; rdfs:subClassOf obo:PATO_0002264 . obo:PATO_0000947 obo:IAO_0000115 "A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section." ; oboInOwl:hasExactSynonym "ellipse-shaped", "ellipsoid", "elliptical" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "oval", "ovoid" ; oboInOwl:id "PATO:0000947" ; oboInOwl:inSubset pato:cell_quality, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "elliptic" ; rdfs:subClassOf obo:PATO_0002318 . obo:PATO_0000955 obo:IAO_0000115 "A fertility quality inhering in a bearer by virtue of the bearer's being capable of initiating, sustaining, or supporting reproduction." ; obo:RO_0002604 obo:PATO_0000956 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000955" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "fertile" ; rdfs:subClassOf obo:PATO_0000274 ; owl:disjointWith obo:PATO_0000956 . obo:PATO_0000956 obo:IAO_0000115 "A fertility quality inhering in a bearer by virtue of the bearer's being incapable of initiating, sustaining, or supporting reproduction." ; obo:RO_0002604 obo:PATO_0000955 ; oboInOwl:hasAlternativeId "WBPhenotype:0000311" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000956" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "sterile" ; rdfs:subClassOf obo:PATO_0000274 . obo:PATO_0000957 obo:IAO_0000115 "An optical quality which obtains by virtue of the ability of the bearer to absorb visible light." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000957" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "opacity" ; rdfs:subClassOf obo:PATO_0001300 . obo:PATO_0000964 obo:IAO_0000115 "A optical quality inhering in a bearer by virtue of the bearer's lacking opacity." ; obo:RO_0002604 obo:PATO_0000963 ; oboInOwl:hasExactSynonym "clear", "hyaline" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000964" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "transparent" ; rdfs:subClassOf obo:PATO_0000957 . obo:PATO_0000965 obo:IAO_0000115 "A pattern quality of inhering in a bearer by virtue of the correspondence in size, shape, and relative position of the bearer's parts on opposite sides of a dividing line or median plane or about a center or axis." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0000965" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "symmetry" ; rdfs:subClassOf obo:PATO_0000060 . obo:PATO_0001005 obo:IAO_0000115 "A time quality inhering in a bearer by virtue of the time it elapses for the bearer to respond to a stimulus." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001005" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:comment "This class is a candidate for obsoletion. The definition is not clear, and the placement under \"delayed\" is not consistent with the definition." ; rdfs:label "latency" ; rdfs:subClassOf obo:PATO_0000502 . obo:PATO_0001018 obo:IAO_0000115 "A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities." ; oboInOwl:hasAlternativeId "PATO:0002079" ; oboInOwl:hasDbXref "Wikipedia:Physical_property" ; oboInOwl:hasExactSynonym "relational physical quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001018" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "physical quality" ; rdfs:subClassOf obo:PATO_0001241 . obo:PATO_0001029 obo:IAO_0000115 "A physical quality inhering in a bearer by virtue of ratio of the bearer's output to the bearer's input." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001029" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "efficiency" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0001046 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's disposition to resist to a stimulus." ; obo:RO_0002604 obo:PATO_0001043 ; oboInOwl:hasExactSynonym "resistance" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001046" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim, pato:relational_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "resistance to" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0001159 obo:IAO_0000115 "A concentration quality inhering in a bearer by virtue of the bearer's exhibiting concentration." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001159" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "concentrated" ; rdfs:subClassOf obo:PATO_0000033 . obo:PATO_0001162 obo:IAO_0000115 "A concentration which is higher relative to the normal or average." ; obo:RO_0002604 obo:PATO_0001163 ; oboInOwl:hasExactSynonym "high concentration" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001162" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased concentration" ; rdfs:subClassOf obo:PATO_0001159, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001159 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001163 obo:IAO_0000115 "A concentration which is lower relative to the normal or average." ; obo:RO_0002604 obo:PATO_0001162 ; oboInOwl:hasExactSynonym "low concentration" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001163" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased concentration" ; rdfs:subClassOf obo:PATO_0001159, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001159 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001178 obo:IAO_0000115 "A resistance quality inhering in a bearer by virtue of the bearer's resistance to a stimulus." ; oboInOwl:hasExactSynonym "resistant" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001178" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "resistant to" ; rdfs:subClassOf obo:PATO_0001046 . obo:PATO_0001192 obo:IAO_0000115 "A response quality inhering in a bearer by virtue of the bearer's excessive reaction to a stimulus or an agent." ; obo:RO_0002604 obo:PATO_0001194 ; oboInOwl:hasExactSynonym "hyperresponsive", "increased responsivity" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001192" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "hyperresponsive to" ; rdfs:subClassOf obo:PATO_0000487, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000487 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001194 obo:IAO_0000115 "A response quality inhering in a bearer by virtue of the bearer's limited reaction to a stimulus or an agent." ; obo:RO_0002604 obo:PATO_0001192 ; oboInOwl:hasExactSynonym "decreased responsivity", "hyporesponsive" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001194" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "hyporesponsive to" ; rdfs:subClassOf obo:PATO_0000487, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000487 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001227 obo:IAO_0000115 "A variability quality inhering in a bearer by virtue of whether the bearer exhibits variation or change." ; obo:RO_0002604 obo:PATO_0000438 ; oboInOwl:hasExactSynonym "variable" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001227" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "variant" ; rdfs:subClassOf obo:PATO_0001303 . obo:PATO_0001236 obo:IAO_0000115 "A quality which inheres in an process." ; oboInOwl:hasAlternativeId "PATO:0001239", "PATO:0001240" ; oboInOwl:hasExactSynonym "quality of a process", "quality of occurrent", "quality of process", "relational quality of occurrent" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001236" ; a owl:Class ; rdfs:comment "See comments of relational quality of a physical entity." ; rdfs:label "process quality" ; rdfs:subClassOf obo:PATO_0000001 ; owl:disjointWith obo:PATO_0001241 . obo:PATO_0001241 obo:IAO_0000111 "physical object quality" ; obo:IAO_0000115 "A quality which inheres in a continuant." ; obo:IAO_0000412 ; oboInOwl:hasAlternativeId "PATO:0001237", "PATO:0001238" ; oboInOwl:hasDbXref "snap:Quality" ; oboInOwl:hasExactSynonym "monadic quality of a continuant", "multiply inhering quality of a physical entity", "quality of a continuant", "quality of a single physical entity", "quality of an object", "quality of continuant" ; oboInOwl:hasNarrowSynonym "monadic quality of an object", "monadic quality of continuant" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001241" ; a owl:Class ; rdfs:comment "Relational qualities are qualities that hold between multiple entities. Normal (monadic) qualities such as the shape of a eyeball exist purely as a quality of that eyeball. A relational quality such as sensitivity to light is a quality of that eyeball (and connecting nervous system) as it relates to incoming light waves/particles." ; rdfs:label "physical object quality" ; rdfs:subClassOf obo:BFO_0000019, obo:PATO_0000001 . obo:PATO_0001242 obo:IAO_0000115 "A physical quality which is equal to the distance between repeating units of a wave pattern." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001242" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "wavelength" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0001290 obo:IAO_0000115 "A fluorescence quality inhering in a bearer by virtue of emitting light during exposure to radiation from an external source." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001290" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "fluorescent" ; rdfs:subClassOf obo:PATO_0000018 . obo:PATO_0001296 obo:IAO_0000115 "A scalar optical quality which obtains by the magnitude of the light emitted by the bearer." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001296" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "luminous flux" ; rdfs:subClassOf obo:PATO_0001300 . obo:PATO_0001300 obo:IAO_0000115 "An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001300" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "optical quality" ; rdfs:subClassOf obo:PATO_0070060 . obo:PATO_0001301 obo:IAO_0000115 "An optical quality that is the mixture, purity or pattern of wavelengths of light perceived by the observer." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001301" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "chromatic property" ; rdfs:subClassOf obo:PATO_0001300 . obo:PATO_0001303 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's disposition to varying or changing." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "variability of a physical quality" ; oboInOwl:id "PATO:0001303" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "variability" ; rdfs:subClassOf obo:PATO_0000001 . obo:PATO_0001309 obo:IAO_0000115 "A process quality inhering in a bearer by virtue of the bearer's magnitude of the temporal extent between the starting and ending point." ; oboInOwl:hasAlternativeId "PATO:0000081" ; oboInOwl:hasExactSynonym "period" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "time" ; oboInOwl:id "PATO:0001309" ; oboInOwl:inSubset pato:attribute_slim, pato:hpo_slim ; a owl:Class ; rdfs:label "duration" ; rdfs:subClassOf obo:PATO_0002062 . obo:PATO_0001340 obo:IAO_0000115 "A biological sex quality inhering in an organism or a population with both male and female sexual organs in one individual." ; oboInOwl:hasExactSynonym "hermaphroditic", "intersex" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001340" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "hermaphrodite" ; rdfs:subClassOf obo:PATO_0001894 . obo:PATO_0001362 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of the bearer's disposition to being easily damaged or destroyed." ; obo:RO_0002604 obo:PATO_0001716 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001362" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "fragile" ; rdfs:subClassOf obo:PATO_0001662 . obo:PATO_0001375 a owl:Class . obo:PATO_0001396 obo:IAO_0000115 "A monadic quality of continuant that exists at the cellular level of organisation." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001396" ; a owl:Class ; rdfs:label "cellular quality" ; rdfs:subClassOf obo:PATO_0070044 . obo:PATO_0001404 obo:IAO_0000115 "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001404" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "nucleate quality" ; rdfs:subClassOf obo:PATO_0001396 . obo:PATO_0001405 obo:IAO_0000115 "A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001405" ; oboInOwl:inSubset pato:cell_quality, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "anucleate" ; rdfs:subClassOf obo:PATO_0001404 . obo:PATO_0001408 obo:IAO_0000115 "A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001408" ; oboInOwl:inSubset pato:cell_quality, pato:value_slim ; a owl:Class ; rdfs:label "ciliatedness" ; rdfs:subClassOf obo:PATO_0001396 . obo:PATO_0001422 obo:IAO_0000115 "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001422" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "dead" ; rdfs:subClassOf obo:PATO_0000169 . obo:PATO_0001433 obo:IAO_0000115 "A quality of a single process which describes the growth of an organism, structure, or group of organisms." ; oboInOwl:hasAlternativeId "PATO:0001489" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "growth quality of a process", "growth timing quality" ; oboInOwl:id "PATO:0001433" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "growth quality of occurrent" ; rdfs:subClassOf obo:PATO_0001236 . obo:PATO_0001434 obo:IAO_0000115 "An organismal quality inhering in a bearer by virtue of the bearer's ability to produce new life or offspring." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001434" ; a owl:Class ; rdfs:label "reproductive quality" ; rdfs:subClassOf obo:PATO_0001995 . obo:PATO_0001435 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of the bearer's having connection or association with another entity." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001435" ; oboInOwl:inSubset pato:attribute_slim, pato:relational_slim ; a owl:Class ; rdfs:label "attachment quality" ; rdfs:subClassOf obo:PATO_0000141 . obo:PATO_0001442 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of whether the bearer includes all its components." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001442" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "wholeness" ; rdfs:subClassOf obo:PATO_0000141 . obo:PATO_0001444 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of the bearer's components no longer being in a single contiguous unit." ; oboInOwl:hasAlternativeId "PATO:0001443", "PATO:0001820" ; oboInOwl:hasExactSynonym "fragmented" ; oboInOwl:hasNarrowSynonym "fractured" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "cracked", "hemorrhaged", "split", "torn" ; oboInOwl:id "PATO:0001444" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "broken" ; rdfs:subClassOf obo:PATO_0001442 . obo:PATO_0001453 obo:IAO_0000115 "An attachment quality inhering in a bearer by virtue of the bearer's lacking connection or association with another entity." ; oboInOwl:hasExactSynonym "detached" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001453" ; oboInOwl:inSubset pato:mpath_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "detached from" ; rdfs:subClassOf obo:PATO_0001435 . obo:PATO_0001457 obo:IAO_0000115 "A quality of a process inhering in bearer by virtue of the bearer's disposition to respond to stimulation." ; oboInOwl:hasExactSynonym "sensitivity of occurrent" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001457" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim, pato:relational_slim ; a owl:Class ; rdfs:label "sensitivity of a process" ; rdfs:subClassOf obo:PATO_0002062 . obo:PATO_0001472 obo:IAO_0000115 "A depth which is relatively low." ; obo:RO_0002604 obo:PATO_0001596 ; oboInOwl:hasAlternativeId "PATO:0001692" ; oboInOwl:hasExactSynonym "low depth", "shallow" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001472" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased depth" ; rdfs:subClassOf obo:PATO_0000587, obo:PATO_0001595 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001595 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001475 obo:IAO_0000115 "A position which is relatively high." ; obo:RO_0002604 obo:PATO_0001476 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "high position" ; oboInOwl:id "PATO:0001475" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased position" ; rdfs:subClassOf obo:PATO_0000140, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001476 obo:IAO_0000115 "A positional which is relatively low." ; obo:RO_0002604 obo:PATO_0001475 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "low position" ; oboInOwl:id "PATO:0001476" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased position" ; rdfs:subClassOf obo:PATO_0000140, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001477 obo:IAO_0000115 "A positional quality inhering in a bearer by virtue of the bearer's being drawn in or pulled back from any given point." ; oboInOwl:hasBroadSynonym "moved" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "retruded" ; oboInOwl:id "PATO:0001477" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "retracted" ; rdfs:subClassOf obo:PATO_0000140 . obo:PATO_0001490 obo:IAO_0000115 "A growth quality of a process inhering in an organism, structure, or group of organisms by virtue of the bearer's reduced or increased growth." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001490" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "heterochronic growth" ; rdfs:subClassOf obo:PATO_0001433 . obo:PATO_0001492 obo:IAO_0000115 "The rate or speed of the change in size of an individual entity or change in number of a population." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001492" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "growth rate" ; rdfs:subClassOf obo:PATO_0000161 . obo:PATO_0001495 obo:IAO_0000115 "A concave quality inhering in a bearer by virtue of the bearer's shape being a V-shaped cut." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "indented" ; oboInOwl:id "PATO:0001495" ; oboInOwl:inSubset pato:cell_quality, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "notched" ; rdfs:subClassOf obo:PATO_0001857 . obo:PATO_0001496 obo:IAO_0000115 "A reproductive quality inhering in the young of an animal by virtue of the bearer's being cared for at one time." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001496" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "brood quality" ; rdfs:subClassOf obo:PATO_0001434 . obo:PATO_0001509 obo:IAO_0000115 "A quality of a single physical entity that arises by virtue of whether the bearer exhibits the ability to perform a regular function(s)." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001509" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "functionality" ; rdfs:subClassOf obo:PATO_0001241 . obo:PATO_0001510 obo:IAO_0000115 "A functionality quality held by the bearer when the latter is able to perform a regular function(s)." ; obo:RO_0002604 obo:PATO_0001511 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001510" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "functional" ; rdfs:subClassOf obo:PATO_0001509 . obo:PATO_0001511 obo:IAO_0000115 "A disfunctional quality held by the bearer when the latter is unable to perform a regular function(s)." ; obo:RO_0002604 obo:PATO_0001510 ; oboInOwl:hasAlternativeId "PATO:0001640" ; oboInOwl:hasExactSynonym "disfunctional", "functional failure" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "defective", "failure" ; oboInOwl:id "PATO:0001511" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "non-functional" ; rdfs:subClassOf obo:PATO_0001509 . obo:PATO_0001549 obo:IAO_0000115 "A sensitivity toward an external stimulus which is higher than normal/average." ; obo:RO_0002604 obo:PATO_0001550 ; oboInOwl:hasExactSynonym "high sensitivity toward", "increased sensitivity" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001549" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased sensitivity toward" ; rdfs:subClassOf obo:PATO_0000516, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000516 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001550 obo:IAO_0000115 "A sensitivity toward an external stimulus which is lower than normal/average." ; obo:RO_0002604 obo:PATO_0001549 ; oboInOwl:hasExactSynonym "decreased sensitivity", "low sensitivity toward" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001550" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased sensitivity toward" ; rdfs:subClassOf obo:PATO_0000516, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000516 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001551 obo:IAO_0000115 "A sensitivity of a process which is higher than normal or average." ; obo:RO_0002604 obo:PATO_0001552 ; oboInOwl:hasExactSynonym "high sensitivity of occurrent", "increased sensitivity of occurrent" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001551" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased sensitivity of a process" ; rdfs:subClassOf obo:PATO_0001457, obo:PATO_0002304 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001457 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001552 obo:IAO_0000115 "A sensitivity of a process which is lower than normal or average." ; obo:RO_0002604 obo:PATO_0001551 ; oboInOwl:hasExactSynonym "decreased sensitivity of occurrent", "low sensitivity of occurrent" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001552" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased sensitivity of a process" ; rdfs:subClassOf obo:PATO_0001457, obo:PATO_0002302 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001457 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001555 obo:IAO_0000115 "The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts." ; oboInOwl:hasDbXref "OBO_REL:has_part" ; oboInOwl:hasExactSynonym "extra or missing physical or functional parts", "has or lacks parts of type", "mereological quality", "number of" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "cardinality", "number" ; oboInOwl:id "PATO:0001555" ; oboInOwl:inSubset pato:attribute_slim, pato:relational_slim ; a owl:Class ; rdfs:label "has number of" ; rdfs:subClassOf obo:PATO_0001241, [ a owl:Restriction ; owl:onProperty obo:RO_0015012 ; owl:someValuesFrom obo:PATO_0000070 ] . obo:PATO_0001558 obo:IAO_0000115 "A quality of a process inhering in a bearer by virtue of the bearer's lacking a processual part as specified by the additional entity." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001558" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "lacking processual parts" ; rdfs:subClassOf obo:PATO_0001564, [ a owl:Restriction ; owl:onProperty obo:RO_0015012 ; owl:someValuesFrom obo:PATO_0000462 ] . obo:PATO_0001559 obo:IAO_0000115 "A functionality quality which is held by the bearer when the latter is able to perform additional or different function(s)." ; oboInOwl:hasExactSynonym "having supernumerary functions" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001559" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "having extra function" ; rdfs:subClassOf obo:PATO_0001509, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001509 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001564 obo:IAO_0000115 "A quality of a process inhering in a bearer by virtue of the bearer's processual parts." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001564" ; oboInOwl:inSubset pato:relational_slim ; a owl:Class ; rdfs:label "extra or missing processual parts" ; rdfs:subClassOf obo:PATO_0001236 . obo:PATO_0001570 obo:IAO_0000115 "A quality of a process inhering in a bearer by virtue of the bearer's having fewer processual parts." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001570" ; oboInOwl:inSubset pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "having decreased processual parts" ; rdfs:subClassOf obo:PATO_0001564 . obo:PATO_0001583 obo:IAO_0000115 "A variability which is relatively low." ; obo:RO_0002604 obo:PATO_0001584 ; oboInOwl:hasExactSynonym "low variability" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001583" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased variability" ; rdfs:subClassOf obo:PATO_0001227, obo:PATO_0002301 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001227 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001584 obo:IAO_0000115 "A variability which is relatively high." ; obo:RO_0002604 obo:PATO_0001583 ; oboInOwl:hasExactSynonym "high variability" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001584" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased variability" ; rdfs:subClassOf obo:PATO_0001227, obo:PATO_0002300 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001227 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001595 obo:IAO_0000115 "A 1-D extent quality inhering in a bearer by virtue of the bearer's downward or backward or inward dimension." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001595" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "depth" ; rdfs:subClassOf obo:PATO_0001708 . obo:PATO_0001596 obo:IAO_0000115 "A depth quality which is relatively high." ; obo:RO_0002604 obo:PATO_0001472 ; oboInOwl:hasAlternativeId "PATO:0001666" ; oboInOwl:hasExactSynonym "deep" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001596" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased depth" ; rdfs:subClassOf obo:PATO_0000586, obo:PATO_0001595 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001595 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001597 obo:IAO_0000115 "An oriented quality inhering in a bearer by virtue of the bearer's being turned outward in placement." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001597" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "everted" ; rdfs:subClassOf obo:PATO_0000614 . obo:PATO_0001598 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's extending out above or beyond a surface or boundary." ; oboInOwl:hasAlternativeId "PATO:0001644" ; oboInOwl:hasExactSynonym "protruding", "relational protruding quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001598" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "protruding" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0001599 obo:IAO_0000115 "An oriented quality inhering in a bearer by virtue of the bearer's being relocated around an axis." ; oboInOwl:hasExactSynonym "rotation" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001599" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "rotated" ; rdfs:subClassOf obo:PATO_0000614 . obo:PATO_0001603 obo:IAO_0000115 "A life span which is relatively high." ; obo:RO_0002604 obo:PATO_0001604 ; oboInOwl:hasExactSynonym "high life span" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001603" ; a owl:Class ; rdfs:label "increased life span" ; rdfs:subClassOf obo:PATO_0000050, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000050 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001604 obo:IAO_0000115 "A life span which is relatively low." ; obo:RO_0002604 obo:PATO_0001603 ; oboInOwl:hasExactSynonym "low life span" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001604" ; a owl:Class ; rdfs:label "decreased life span" ; rdfs:subClassOf obo:PATO_0000050, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000050 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001624 obo:IAO_0000115 "A functionality quality held by the bearer when the latter exhibits decreased ability to perform a regular function(s)." ; obo:RO_0002604 obo:PATO_0001625 ; oboInOwl:hasAlternativeId "PATO:0001556", "PATO:0001568", "PATO:0001641", "PATO:0001642" ; oboInOwl:hasBroadSynonym "dysfunction", "dysfunctional" ; oboInOwl:hasExactSynonym "having decreased function", "lacks function of type", "low functionality", "partial functionality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "impaired" ; oboInOwl:id "PATO:0001624" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased functionality" ; rdfs:subClassOf obo:PATO_0001510, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001510 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001625 obo:IAO_0000115 "A functional quality held by the bearer when the latter exhibits increased ability to perform a regular function(s)." ; obo:RO_0002604 obo:PATO_0001624 ; oboInOwl:hasExactSynonym "high functionality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001625" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased functionality" ; rdfs:subClassOf obo:PATO_0001510, obo:PATO_0001559 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001510 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001632 obo:IAO_0000115 "A spatial quality inhering in a bearer by virtue of the bearer's being located toward the front of an organism relative to another entity." ; oboInOwl:hasExactSynonym "preceding" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001632" ; oboInOwl:inSubset pato:mpath_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "anterior to" ; rdfs:subClassOf obo:PATO_0000140 . obo:PATO_0001633 obo:IAO_0000115 "A spatial quality inhering in a bearer by virtue of the bearer's being located toward the rear of an organism relative to another entity." ; oboInOwl:hasExactSynonym "posterior (human torso)", "superior (human head)" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001633" ; oboInOwl:inSubset pato:mpath_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "posterior to" ; rdfs:subClassOf obo:PATO_0000140 . obo:PATO_0001650 obo:IAO_0000115 "A resistance to a stimulus which is relatively high." ; obo:RO_0002604 obo:PATO_0001651 ; oboInOwl:hasExactSynonym "high resistance to", "increased resistance" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001650" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased resistance to" ; rdfs:subClassOf obo:PATO_0001178, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001178 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001651 obo:IAO_0000115 "A resistance to a stimulus which is relatively low." ; obo:RO_0002604 obo:PATO_0001650 ; oboInOwl:hasExactSynonym "decreased resistance", "low resistance to" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001651" ; oboInOwl:inSubset pato:disposition_slim, pato:relational_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased resistance to" ; rdfs:subClassOf obo:PATO_0001178, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001178 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001652 obo:IAO_0000115 "A spatial quality inhering in a bearer by virtue of the bearer's spatial positioning with respect to an additional entity." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001652" ; oboInOwl:inSubset pato:attribute_slim, pato:relational_slim ; a owl:Class ; rdfs:label "alignment" ; rdfs:subClassOf obo:PATO_0000140, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:PATO_0000133 ] . obo:PATO_0001662 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of the bearer's disposition to being damaged or destroyed." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001662" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "fragility" ; rdfs:subClassOf obo:PATO_0000141 . obo:PATO_0001677 obo:IAO_0000115 "An efficiency quality inhering in a bearer by virtue of the bearer's lacking efficiency." ; obo:RO_0002604 obo:PATO_0001678 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001677" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "inefficient" ; rdfs:subClassOf obo:PATO_0001029 . obo:PATO_0001707 obo:IAO_0000115 "A behavioral quality of a process inhering in a bearer by virtue of the bearer's exhibiting marked activity." ; obo:RO_0002604 obo:PATO_0001706 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001707" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "behavioural active" ; rdfs:subClassOf obo:PATO_0002265 . obo:PATO_0001708 obo:IAO_0000115 "A size quality inhering in an bearer by virtue of the bearer's extension in one dimension." ; oboInOwl:hasExactSynonym "1-D size" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001708" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "1-D extent" ; rdfs:subClassOf obo:PATO_0000117 . obo:PATO_0001710 obo:IAO_0000115 "A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions." ; oboInOwl:hasExactSynonym "3D size" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001710" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "3-D extent" ; rdfs:subClassOf obo:PATO_0000117 . obo:PATO_0001752 obo:IAO_0000115 "A heterochronic growth quality inhering in an organism, structure, or group of organisms by virtue of the bearer's increased growth." ; obo:RO_0002604 obo:PATO_0001749 ; oboInOwl:hasExactSynonym "hyperplastic growth" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001752" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "peramorphic growth" ; rdfs:subClassOf obo:PATO_0001490 . obo:PATO_0001754 obo:IAO_0000115 "A peramorphic growth quality which is due to an earlier onset." ; oboInOwl:hasExactSynonym "precocious growth" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001754" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "predisplaced growth" ; rdfs:subClassOf obo:PATO_0001752 . obo:PATO_0001767 oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001767" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "semi-fertile" ; rdfs:subClassOf obo:PATO_0000274 . obo:PATO_0001769 obo:IAO_0000115 "A positional quality inhering in a bearer by virtue of the bearer's location of features or characteristics along an axis." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "cellular polarity" ; oboInOwl:id "PATO:0001769" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "positional polarity" ; rdfs:subClassOf obo:PATO_0000140 . obo:PATO_0001780 obo:IAO_0000115 "A size quality inhering in a bearer by virtue of the bearer's being abnormally developed, usually due to malnutrition." ; oboInOwl:hasExactSynonym "dystrophied" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "dystrophy" ; oboInOwl:id "PATO:0001780" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "dystrophic" ; rdfs:subClassOf obo:PATO_0000587 . obo:PATO_0001794 obo:IAO_0000115 "A shape quality inhering in a bearer by virtue of the bearer's being wound in a continuous series of loops." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001794" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "coiling" ; rdfs:subClassOf obo:PATO_0000052 . obo:PATO_0001795 obo:IAO_0000115 "A coiling which is relatively high." ; obo:RO_0002604 obo:PATO_0001796 ; oboInOwl:hasExactSynonym "high coiling" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001795" ; oboInOwl:inSubset pato:cell_quality, pato:value_slim ; a owl:Class ; rdfs:label "increased coiling" ; rdfs:subClassOf obo:PATO_0000404, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000404 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001796 obo:IAO_0000115 "A coiling which is relatively low." ; obo:RO_0002604 obo:PATO_0001795 ; oboInOwl:hasExactSynonym "low coiling" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001796" ; oboInOwl:inSubset pato:cell_quality, pato:value_slim ; a owl:Class ; rdfs:label "decreased coiling" ; rdfs:subClassOf obo:PATO_0000404, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000404 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001798 obo:IAO_0000115 "A shape quality inhering in a bearer by virtue of the bearer's having multiple angles in its length." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "tightly curled", "twisted" ; oboInOwl:id "PATO:0001798" ; oboInOwl:inSubset pato:cell_quality, pato:value_slim ; a owl:Class ; rdfs:label "kinked" ; rdfs:subClassOf obo:PATO_0000617 . obo:PATO_0001810 obo:IAO_0000115 "A grooved texture quality inhering in a bearer by virtue of the bearer's being marked by one or more creases in a normally smooth surface." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001810" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "wrinkled" ; rdfs:subClassOf obo:PATO_0002255 . obo:PATO_0001818 obo:IAO_0000115 "A quality of a single process inhering in a bearer by virtue of the bearer's increasing over time." ; obo:RO_0002604 obo:PATO_0002026 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001818" ; oboInOwl:inSubset pato:hpo_slim, pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "progressive" ; rdfs:subClassOf obo:PATO_0000057 . obo:PATO_0001819 obo:IAO_0000115 "A morphological quality inhering in a bearer by virtue of the bearer's absence or closure of a normal body orifice or tubular passage." ; oboInOwl:hasExactSynonym "atresia" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001819" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "atretic" ; rdfs:subClassOf obo:PATO_0000608 . obo:PATO_0001834 obo:IAO_0000115 "A fertility which is relatively low." ; obo:RO_0002604 obo:PATO_0001835 ; oboInOwl:hasExactSynonym "low fertility" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001834" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased fertility" ; rdfs:subClassOf obo:PATO_0000955, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000955 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001835 obo:IAO_0000115 "A fertility which is relatively high." ; obo:RO_0002604 obo:PATO_0001834 ; oboInOwl:hasExactSynonym "high fertility" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001835" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased fertility" ; rdfs:subClassOf obo:PATO_0000955, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000955 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001836 obo:IAO_0000115 "A structural quality inhering in a bearer with some kind of aperture or opening that is blocked or clogged." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001836" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "congested" ; rdfs:subClassOf obo:PATO_0000141 . obo:PATO_0001851 obo:IAO_0000115 "A structure quality inhering in a bearer by virtue of the bearer's exhibiting transient abnormal enlargement, not due to cell proliferation." ; oboInOwl:hasNarrowSynonym "swelling" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001851" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "swollen" ; rdfs:subClassOf obo:PATO_0000141, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:PATO_0000586 ], [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:PATO_0001598 ] . obo:PATO_0001852 obo:IAO_0000115 "A positional quality inhering in a bearer by virtue of the bearer's being out of its usual or proper place, or position." ; oboInOwl:hasAlternativeId "PATO:0001479", "PATO:0002158", "PATO:0002159" ; oboInOwl:hasExactSynonym "dislocation", "luxated", "luxation", "relational dislocated quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001852" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "dislocated" ; rdfs:subClassOf obo:PATO_0002181 . obo:PATO_0001857 obo:IAO_0000115 "A shape quality in a bearer by virtue of the bearer's curving inward." ; obo:RO_0002604 obo:PATO_0001355 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001857" ; oboInOwl:inSubset pato:cell_quality, pato:value_slim ; a owl:Class ; rdfs:label "concave" ; rdfs:subClassOf obo:PATO_0002005 . obo:PATO_0001873 obo:IAO_0000115 "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section." ; oboInOwl:hasAlternativeId "PATO:0001203" ; oboInOwl:hasExactSynonym "rod-like", "rod-shaped" ; oboInOwl:hasNarrowSynonym "tubulate" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001873" ; oboInOwl:inSubset pato:cell_quality, pato:value_slim ; a owl:Class ; rdfs:label "cylindrical" ; rdfs:subClassOf obo:PATO_0002007, [ a owl:Restriction ; owl:onProperty obo:RO_0015011 ; owl:someValuesFrom obo:PATO_0000411 ] . obo:PATO_0001894 obo:IAO_0000115 "An organismal quality inhering in a bearer by virtue of the bearer's physical expression of sexual characteristics." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001894" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "phenotypic sex" ; rdfs:subClassOf obo:PATO_0000047 . obo:PATO_0001906 obo:IAO_0000115 "A physical quality inhering in a bearer by virtue of the bearer's participation in movement." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001906" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "movement quality" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0001908 a owl:Class . obo:PATO_0001912 obo:IAO_0000115 "A quality of a single process inhering in a bearer by virtue of the state of bearer's mechanical, physical, and biochemical processes." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001912" ; a owl:Class ; rdfs:label "physiological state" ; rdfs:subClassOf obo:PATO_0001236 . obo:PATO_0001926 obo:IAO_0000115 "A fluorescence which is higher than normal." ; obo:RO_0002604 obo:PATO_0001927 ; oboInOwl:hasExactSynonym "high fluorescence" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001926" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "increased fluorescence" ; rdfs:subClassOf obo:PATO_0001290, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001290 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001927 obo:IAO_0000115 "A fluorescence which is lower than normal." ; obo:RO_0002604 obo:PATO_0001926 ; oboInOwl:hasExactSynonym "low fluorescence" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001927" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased fluorescence" ; rdfs:subClassOf obo:PATO_0001290, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001290 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001928 obo:IAO_0000115 "A texture quality inhering in a bearer by virtue of a local accumulation of fluid underneath the surface of the bearer." ; oboInOwl:hasNarrowSynonym "blistering" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001928" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "blistered" ; rdfs:subClassOf obo:PATO_0000150 . obo:PATO_0001929 obo:IAO_0000115 "A variability quality inhering in a bearer by virtue of whether the bearer exhibits shape variation or change." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001929" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "variability of shape" ; rdfs:subClassOf obo:PATO_0001303, [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:PATO_0000052 ] . obo:PATO_0001930 obo:IAO_0000115 "A quality inhering in a bearer by virtue the bearer's having or exhibiting variation its shape." ; obo:RO_0002604 obo:PATO_0001931 ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001930" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "variant shape" ; rdfs:subClassOf obo:PATO_0001929 . obo:PATO_0001995 obo:IAO_0000115 "A quality that inheres in an entire organism or part of an organism." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001995" ; a owl:Class ; rdfs:label "organismal quality" ; rdfs:subClassOf obo:PATO_0001241 . obo:PATO_0001997 obo:IAO_0000115 "An amount which is relatively low." ; obo:RO_0002604 obo:PATO_0000470 ; oboInOwl:hasAlternativeId "PATO:0000419", "PATO:0000468" ; oboInOwl:hasExactSynonym "decreased number", "present in fewer numbers in organism" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "decreased", "reduced", "subnumerary" ; oboInOwl:id "PATO:0001997" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "decreased amount" ; rdfs:subClassOf obo:PATO_0000467, obo:PATO_0002301 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0001999 obo:IAO_0000115 "The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type." ; oboInOwl:hasExactSynonym "loss of" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0001999" ; oboInOwl:inSubset pato:relational_slim ; a owl:Class ; rdfs:label "lacks parts or has fewer parts of type" ; rdfs:subClassOf obo:PATO_0002083 . obo:PATO_0002000 obo:IAO_0000115 "A quality of physical entities inhering in a bearer by virtue of the bearer's lacking a physical part as specified by the additional entity." ; oboInOwl:hasAlternativeId "PATO:0001557" ; oboInOwl:hasDbXref "OBO_REL:lacks_part" ; oboInOwl:hasExactSynonym "lacks all physical parts of type" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002000" ; oboInOwl:inSubset pato:relational_slim ; a owl:Class ; rdfs:comment "Example: [E=organism Q=lacks_all_parts_of_type E2=Wing] - applies to an organism. A relational quality in which the bearer entity has no parts of the specified type. The bearer of this quality has_part = 0 of the indicated entity type, where a comparable organism usually has at least 1 part of the same type. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e lacks all parts of type X at time t, then there exists no instances x of X at t such that x part_of e that has no wings, where wings are normally present in that organism type. In OWL this is equivalent to a restriction on the OBO_REL:has_part relation with cardinality=0, i.e has_part 0 E2." ; rdfs:label "lacks all parts of type" ; rdfs:subClassOf obo:PATO_0001999, [ a owl:Restriction ; owl:onProperty obo:RO_0015012 ; owl:someValuesFrom obo:PATO_0000462 ] . obo:PATO_0002001 obo:IAO_0000115 "The bearer of this quality has_part < n AND has_part > 0 of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly." ; obo:RO_0002604 obo:PATO_0002002 ; oboInOwl:hasAlternativeId "PATO:0001569" ; oboInOwl:hasExactSynonym "decreased number of", "has decreased number of", "has fewer physical parts of type" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002001" ; oboInOwl:inSubset pato:relational_slim ; a owl:Class ; rdfs:comment "Example: [E=hand Q=has_fewer_parts_of_type E2=digit] - applies to an organism that has no less fingers than is normal for organisms of that type." ; rdfs:label "has fewer parts of type" ; rdfs:subClassOf obo:PATO_0001999, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001999 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002002 obo:IAO_0000115 "The bearer of this quality has_part > n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part." ; obo:RO_0002604 obo:PATO_0002001 ; oboInOwl:hasAlternativeId "PATO:0001560" ; oboInOwl:hasExactSynonym "has extra parts of", "has increased number of", "having extra physical parts", "having supernumerary physical parts", "increased number of" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002002" ; oboInOwl:inSubset pato:relational_slim ; a owl:Class ; rdfs:comment "In polydactyly, the bearer of the quality is the hand, and the entity type being counted is 'finger'. In EQ syntax, E=hand, Q= E2=finger." ; rdfs:label "has extra parts of type" ; rdfs:subClassOf obo:PATO_0002083, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0002083 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002005 obo:IAO_0000115 "Surface shape that refers to the inward or outward curvature of the surface." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002005" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "concavity" ; rdfs:subClassOf obo:PATO_0000052 . obo:PATO_0002006 obo:IAO_0000115 "A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "2-D projection", "cross-sectional" ; oboInOwl:id "PATO:0002006" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "2-D shape" ; rdfs:subClassOf obo:PATO_0000052 . obo:PATO_0002007 obo:IAO_0000115 "A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave." ; obo:RO_0002604 obo:PATO_0002008 ; oboInOwl:hasDbXref "Image:http://upload.wikimedia.org/wikipedia/commons/0/06/Convex_polygon_illustration1.png" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002007" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:comment "Use this term or an is_a child of this term when the entire shape of the object is known." ; rdfs:label "convex 3-D shape" ; rdfs:subClassOf obo:PATO_0002266, [ a owl:Restriction ; owl:onProperty obo:RO_0015011 ; owl:someValuesFrom obo:PATO_0002006 ] . obo:PATO_0002009 obo:IAO_0000115 "A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002009" ; oboInOwl:inSubset pato:attribute_slim, pato:cell_quality ; a owl:Class ; rdfs:label "branchiness" ; rdfs:subClassOf obo:PATO_0000052 . obo:PATO_0002014 obo:IAO_0000115 "A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002014" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "structure, cavities" ; rdfs:subClassOf obo:PATO_0000141 . obo:PATO_0002016 oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002016" ; a owl:Class ; rdfs:label "magnitude" ; rdfs:subClassOf obo:PATO_0000068 . obo:PATO_0002017 obo:RO_0002604 obo:PATO_0002018 ; oboInOwl:hasExactSynonym "high magnitude" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002017" ; a owl:Class ; rdfs:label "increased magnitude" ; rdfs:subClassOf obo:PATO_0002016 . obo:PATO_0002037 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of the bearer exhibiting deterioration of its structure." ; terms:contributor ; oboInOwl:creation_date "2009-02-03T11:13:19Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002037" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "degeneration" ; rdfs:subClassOf obo:PATO_0000141 . obo:PATO_0002051 obo:IAO_0000115 "An occurrence which is relatively high." ; obo:RO_0002604 obo:PATO_0002052 ; terms:contributor ; oboInOwl:creation_date "2009-03-26T11:10:11Z" ; oboInOwl:hasExactSynonym "increased incidence" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002051" ; a owl:Class ; rdfs:label "increased occurrence" ; rdfs:subClassOf obo:PATO_0000057, obo:PATO_0002304 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000057 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002052 obo:IAO_0000115 "An occurrence which is relatively low." ; obo:RO_0002604 obo:PATO_0002051 ; terms:contributor ; oboInOwl:creation_date "2009-03-26T11:12:35Z" ; oboInOwl:hasExactSynonym "decreased incidence" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002052" ; a owl:Class ; rdfs:label "decreased occurrence" ; rdfs:subClassOf obo:PATO_0000057, obo:PATO_0002302 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000057 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002055 obo:IAO_0000115 "A fragility which is relatively high." ; obo:RO_0002604 obo:PATO_0002056 ; terms:contributor ; oboInOwl:creation_date "2009-03-26T04:01:37Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002055" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "increased fragility" ; rdfs:subClassOf obo:PATO_0001362, obo:PATO_0002305 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001362 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002056 obo:IAO_0000115 "A fragility which is relatively low." ; obo:RO_0002604 obo:PATO_0002055 ; terms:contributor ; oboInOwl:creation_date "2009-03-26T04:02:14Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002056" ; oboInOwl:inSubset pato:disposition_slim, pato:value_slim ; a owl:Class ; rdfs:label "decreased fragility" ; rdfs:subClassOf obo:PATO_0001362, obo:PATO_0002303 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001362 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002062 terms:contributor ; oboInOwl:creation_date "2009-06-05T09:16:46Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002062" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "physical quality of a process" ; rdfs:subClassOf obo:PATO_0001236 . obo:PATO_0002076 obo:IAO_0000115 "A behavioral quality inhering in a bearer by virtue of the bearer's movement." ; terms:contributor ; oboInOwl:creation_date "2009-09-18T02:04:48Z" ; oboInOwl:hasExactSynonym "movement behavioural quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002076" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "movement behavioral quality" ; rdfs:subClassOf obo:PATO_0000186 . obo:PATO_0002083 obo:IAO_0000115 "Having extra or fewer parts." ; terms:contributor ; oboInOwl:creation_date "2009-09-21T10:41:58Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002083" ; oboInOwl:inSubset pato:attribute_slim, pato:relational_slim ; a owl:Class ; rdfs:label "altered number of" ; rdfs:subClassOf obo:PATO_0000051, obo:PATO_0001555 . obo:PATO_0002112 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of the bearer's having a hole or holes, especially a row or array of small holes." ; obo:RO_0002604 obo:PATO_0001821 ; terms:contributor ; oboInOwl:creation_date "2009-10-05T03:37:05Z" ; oboInOwl:hasAlternativeId "PATO:0000649" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "permeable", "pierced" ; oboInOwl:id "PATO:0002112" ; oboInOwl:inSubset pato:mpath_slim, pato:value_slim ; a owl:Class ; rdfs:label "perforate" ; rdfs:subClassOf obo:PATO_0002014 . obo:PATO_0002181 obo:IAO_0000115 "A positional quality inhering in a bearer by virtue the bearer's being changed in position." ; terms:contributor ; oboInOwl:creation_date "2010-03-01T02:56:33Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002181" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "displaced" ; rdfs:subClassOf obo:PATO_0000140 . obo:PATO_0002182 obo:IAO_0000115 "A quality which inheres in a molecular entity, a single molecule, atom, ion, radical etc." ; terms:contributor ; oboInOwl:creation_date "2010-03-10T03:18:15Z" ; oboInOwl:hasAlternativeId "PATO:0002061" ; oboInOwl:hasExactSynonym "relational molecular quality" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002182" ; a owl:Class ; rdfs:label "molecular quality" ; rdfs:subClassOf obo:PATO_0001241 . obo:PATO_0002198 obo:IAO_0000115 "A quality inhering in a bearer by virtue of its constitution." ; terms:contributor ; oboInOwl:creation_date "2010-03-15T04:35:27Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002198" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "quality of a substance" ; rdfs:subClassOf obo:PATO_0001018 . obo:PATO_0002247 obo:IAO_0000115 "A quality inhering in a bearer by virtue of the bearer's having or lacking of substances produced by living organisms that have a color resulting from selective color absorption." ; terms:contributor ; oboInOwl:creation_date "2010-08-09T04:14:00Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002247" ; oboInOwl:inSubset pato:attribute_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "degree of pigmentation" ; rdfs:subClassOf obo:PATO_0000141, [ a owl:Restriction ; owl:onProperty obo:RO_0002610 ; owl:someValuesFrom obo:PATO_0000014 ] . obo:PATO_0002255 obo:IAO_0000115 "Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels." ; terms:contributor ; oboInOwl:creation_date "2010-09-01T10:27:48Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "channeled", "creased" ; oboInOwl:id "PATO:0002255" ; oboInOwl:inSubset pato:value_slim ; a owl:Class ; rdfs:label "grooved" ; rdfs:subClassOf obo:PATO_0000150 . obo:PATO_0002264 obo:IAO_0000115 "A structural quality inhering in a bearer by virtue of the bearer's being arranged in a systematic fashion." ; terms:contributor ; oboInOwl:creation_date "2010-09-16T10:22:52Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002264" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "organization quality" ; rdfs:subClassOf obo:PATO_0000141 . obo:PATO_0002265 obo:IAO_0000115 "A behavioral quality of a process inhering in a bearer by virtue of the bearer's disposition to exhibit marked activity." ; terms:contributor ; oboInOwl:creation_date "2010-09-21T06:56:58Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002265" ; oboInOwl:inSubset pato:attribute_slim, pato:disposition_slim, pato:scalar_slim ; a owl:Class ; rdfs:label "behavioural activity" ; rdfs:subClassOf obo:PATO_0000186 . obo:PATO_0002266 obo:IAO_0000115 "A shape that inheres in a 3 dimensional entity." ; terms:contributor ; oboInOwl:creation_date "2010-10-05T12:31:16Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002266" ; a owl:Class ; rdfs:label "3-D shape" ; rdfs:subClassOf obo:PATO_0000052 . obo:PATO_0002300 obo:IAO_0000115 "A quality that has a value that is increased compared to normal or average." ; obo:RO_0002604 obo:PATO_0002301 ; terms:contributor ; oboInOwl:creation_date "2011-06-16T06:39:43Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002300" ; a owl:Class ; rdfs:label "increased quality" ; rdfs:subClassOf obo:PATO_0000069, [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002301 obo:IAO_0000115 "A quality that has a value that is decreased compared to normal or average." ; obo:RO_0002604 obo:PATO_0002300 ; terms:contributor ; oboInOwl:creation_date "2011-06-16T06:40:15Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002301" ; a owl:Class ; rdfs:label "decreased quality" ; rdfs:subClassOf obo:PATO_0000069, [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002302 obo:IAO_0000115 "A quality of a process that has a value that is decreased compared to normal or average." ; obo:RO_0002604 obo:PATO_0002304 ; terms:contributor ; oboInOwl:creation_date "2011-06-16T06:50:59Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002302" ; a owl:Class ; rdfs:label "decreased process quality" ; rdfs:subClassOf obo:PATO_0001236, obo:PATO_0002301 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002303 obo:IAO_0000115 "A quality of an object that has a value that is decreased compared to normal or average." ; obo:RO_0002604 obo:PATO_0002305 ; terms:contributor ; oboInOwl:creation_date "2011-06-16T06:51:54Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002303" ; a owl:Class ; rdfs:label "decreased object quality" ; rdfs:subClassOf obo:PATO_0001241, obo:PATO_0002301 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001241 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002304 obo:IAO_0000115 "A quality of a process that has a value that is increased compared to normal or average." ; obo:RO_0002604 obo:PATO_0002302 ; terms:contributor ; oboInOwl:creation_date "2011-06-16T06:53:08Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002304" ; a owl:Class ; rdfs:label "increased process quality" ; rdfs:subClassOf obo:PATO_0001236, obo:PATO_0002300 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002305 obo:IAO_0000115 "A quality of an object that has a value that is increased compared to normal or average." ; obo:RO_0002604 obo:PATO_0002303 ; terms:contributor ; oboInOwl:creation_date "2011-06-16T06:54:01Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002305" ; a owl:Class ; rdfs:label "increased object quality" ; rdfs:subClassOf obo:PATO_0001241, obo:PATO_0002300 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0001241 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0002318 obo:IAO_0000115 "A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt" ; terms:contributor ; oboInOwl:creation_date "2011-10-12T12:45:16Z" ; oboInOwl:hasExactSynonym "Lamé curve" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002318" ; a owl:Class ; rdfs:label "superelliptic" ; rdfs:subClassOf obo:PATO_0002006 . obo:PATO_0002323 obo:IAO_0000115 "A temporal distribution pattern of process occurrences within a regulation/reference process." ; terms:contributor ; oboInOwl:creation_date "2011-11-22T01:12:28Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0002323" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "temporal distribution quality" ; rdfs:subClassOf obo:PATO_0002062 . obo:PATO_0002324 obo:IAO_0000115 "The temporal relation between the end of the process with respect to a reference process." ; terms:contributor ; oboInOwl:creation_date "2011-11-23T11:46:00Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "completeness", "extent" ; oboInOwl:id "PATO:0002324" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "offset quality" ; rdfs:subClassOf obo:PATO_0002323 . obo:PATO_0002325 obo:IAO_0000115 "The temporal relation between the start of the process with respect to a reference process." ; terms:contributor ; oboInOwl:creation_date "2011-11-23T11:47:34Z" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:hasRelatedSynonym "initiation" ; oboInOwl:id "PATO:0002325" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "onset quality" ; rdfs:subClassOf obo:PATO_0002323 . obo:PATO_0050000 obo:IAO_0000115 "The number of repeated events per unit time, occurring in a repeating series. (e.g. the number of heart beats occurring over 1 minute)" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0050000" ; a owl:Class ; rdfs:label "rate of occurence" ; rdfs:subClassOf obo:PATO_0000161 . obo:PATO_0055003 obo:IAO_0000115 "A rate of occurrence that is relatively high." ; dc:date "2020-08-19T09:23:19Z"^^xsd:dateTime ; terms:contributor ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0055003" ; a owl:Class ; rdfs:label "increased rate of occurrence" ; rdfs:subClassOf obo:PATO_0000912, obo:PATO_0050000 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0050000 [ a owl:Restriction ; owl:onProperty obo:RO_0015007 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0055004 obo:IAO_0000115 "A rate of occurrence that is relatively low." ; dc:date "2020-08-19T09:24:35Z"^^xsd:dateTime ; terms:contributor ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0055004" ; a owl:Class ; rdfs:label "decreased rate of occurrence" ; rdfs:subClassOf obo:PATO_0000911, obo:PATO_0050000 ; owl:equivalentClass [ a owl:Class ; owl:intersectionOf (obo:PATO_0050000 [ a owl:Restriction ; owl:onProperty obo:RO_0015008 ; owl:someValuesFrom obo:PATO_0000461 ] ) ] . obo:PATO_0070044 obo:IAO_0000115 "A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components." ; oboInOwl:created_by "http://orcid.org/0000-0001-7258-9596" ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0070044" ; a owl:Class ; rdfs:label "anatomical structure quality" ; rdfs:subClassOf obo:PATO_0001241 . obo:PATO_0070060 obo:IAO_0000115 "A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength." ; oboInOwl:hasOBONamespace "quality" ; oboInOwl:id "PATO:0070060" ; oboInOwl:inSubset pato:attribute_slim ; a owl:Class ; rdfs:label "quality of interaction of a substance with electromagnetic radiation" ; rdfs:subClassOf obo:PATO_0002198 . obo:RO_0000052 obo:IAO_0000111 "inheres in"@en ; obo:IAO_0000112 "this fragility is a characteristic of this vase"@en, "this red color is a characteristic of this apple"@en ; obo:IAO_0000115 "a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence."@en ; obo:IAO_0000118 "inheres_in"@en ; obo:RO_0001900 obo:RO_0001901 ; a owl:FunctionalProperty, owl:ObjectProperty ; rdfs:comment "Note that this relation was previously called \"inheres in\", but was changed to be called \"characteristic of\" because BFO2 uses \"inheres in\" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing." ; rdfs:label "characteristic of"@en ; rdfs:subPropertyOf obo:RO_0002314 ; owl:inverseOf obo:RO_0000053 . obo:RO_0000053 obo:IAO_0000111 "bearer of"@en ; obo:IAO_0000112 "this apple is bearer of this red color"@en, "this vase is bearer of this fragility"@en ; obo:IAO_0000115 "Inverse of characteristic_of"@en ; obo:IAO_0000116 "A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist."@en ; obo:IAO_0000118 "bearer_of"@en, "is bearer of"@en ; obo:RO_0001900 obo:RO_0001901 ; a owl:InverseFunctionalProperty, owl:ObjectProperty ; rdfs:label "has characteristic"@en ; rdfs:range obo:BFO_0000020 . obo:RO_0000056 obo:IAO_0000111 "participates in"@en ; obo:IAO_0000112 "this blood clot participates in this blood coagulation"@en, "this input material (or this output material) participates in this process"@en, "this investigator participates in this investigation"@en ; obo:IAO_0000115 "a relation between a continuant and a process, in which the continuant is somehow involved in the process"@en ; obo:IAO_0000118 "participates_in"@en ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000002 ; rdfs:label "participates in"@en ; rdfs:range obo:BFO_0000003 ; owl:inverseOf obo:RO_0000057 . obo:RO_0000057 obo:IAO_0000111 "has participant"@en ; obo:IAO_0000112 "this blood coagulation has participant this blood clot"@en, "this investigation has participant this investigator"@en, "this process has participant this input material (or this output material)"@en ; obo:IAO_0000115 "a relation between a process and a continuant, in which the continuant is somehow involved in the process"@en ; obo:IAO_0000116 "Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time."@en ; obo:IAO_0000118 "has_participant"@en ; terms:source "http://www.obofoundry.org/ro/#OBO_REL:has_participant" ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "has participant"@en ; rdfs:range obo:BFO_0000002 ; owl:propertyChainAxiom (obo:BFO_0000051 obo:RO_0000057 ) . obo:RO_0000079 obo:IAO_0000112 "this catalysis function is a function of this enzyme"@en ; obo:IAO_0000115 "a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists."@en ; obo:IAO_0000118 "function_of"@en, "is function of"@en ; a owl:ObjectProperty ; rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ; rdfs:domain obo:BFO_0000034 ; rdfs:label "function of"@en ; rdfs:subPropertyOf obo:RO_0000052 ; owl:inverseOf obo:RO_0000085 . obo:RO_0000080 obo:IAO_0000112 "this red color is a quality of this apple"@en ; obo:IAO_0000115 "a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A quality inheres in its bearer at all times for which the quality exists."@en ; obo:IAO_0000118 "is quality of"@en, "quality_of"@en ; a owl:ObjectProperty ; rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ; rdfs:label "quality of"@en ; rdfs:subPropertyOf obo:RO_0000052 ; owl:inverseOf obo:RO_0000086 . obo:RO_0000081 obo:IAO_0000112 "this investigator role is a role of this person"@en ; obo:IAO_0000115 "a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists."@en ; obo:IAO_0000118 "is role of"@en, "role_of"@en ; a owl:ObjectProperty ; rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ; rdfs:label "role of"@en ; rdfs:subPropertyOf obo:RO_0000052 ; owl:inverseOf obo:RO_0000087 . obo:RO_0000085 obo:IAO_0000112 "this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)"@en ; obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists."@en ; obo:IAO_0000118 "has_function"@en ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000004 ; rdfs:label "has function"@en ; rdfs:range obo:BFO_0000034 ; rdfs:subPropertyOf obo:RO_0000053 . obo:RO_0000086 obo:IAO_0000112 "this apple has quality this red color"@en ; obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist."@en ; obo:IAO_0000118 "has_quality"@en ; a owl:ObjectProperty ; rdfs:label "has quality"@en ; rdfs:range obo:BFO_0000019 ; rdfs:subPropertyOf obo:RO_0000053 . obo:RO_0000087 obo:IAO_0000112 "this person has role this investigator role (more colloquially: this person has this role of investigator)"@en ; obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence"@en ; obo:IAO_0000116 "A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists."@en ; obo:IAO_0000118 "has_role"@en ; oboInOwl:hasDbXref "RO:0000087" ; oboInOwl:hasOBONamespace "chebi_ontology" ; oboInOwl:id "has_role" ; oboInOwl:is_cyclic false ; oboInOwl:is_transitive false ; oboInOwl:shorthand "has_role" ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000004 ; rdfs:label "has role", "has role"@en ; rdfs:range obo:BFO_0000023 ; rdfs:subPropertyOf obo:RO_0000053 . obo:RO_0000091 obo:IAO_0000115 "a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence"@en ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000004 ; rdfs:label "has disposition"@en ; rdfs:range obo:BFO_0000016 ; rdfs:subPropertyOf obo:RO_0000053 ; owl:inverseOf obo:RO_0000092 . obo:RO_0000092 obo:IAO_0000115 "inverse of has disposition" ; oboInOwl:inSubset obo:RO_0002259 ; a owl:ObjectProperty ; rdfs:comment "This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020." ; rdfs:label "disposition of"@en ; rdfs:subPropertyOf obo:RO_0000052 . obo:RO_0001900 a owl:AnnotationProperty . obo:RO_0002013 obo:IAO_0000115 "A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B." ; oboInOwl:created_by ; oboInOwl:creation_date "2017-05-24T09:30:46Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:label "has regulatory component activity" ; rdfs:subPropertyOf obo:RO_0002017, obo:RO_0002334 . obo:RO_0002014 obo:IAO_0000115 "A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B." ; oboInOwl:created_by ; oboInOwl:creation_date "2017-05-24T09:31:01Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:comment "By convention GO molecular functions are classified by their effector function. Internal regulatory functions are treated as components. For example, NMDA glutmate receptor activity is a cation channel activity with positive regulatory component 'glutamate binding' and negative regulatory components including 'zinc binding' and 'magnesium binding'." ; rdfs:label "has negative regulatory component activity" ; rdfs:subPropertyOf obo:RO_0002013, obo:RO_0002335 . obo:RO_0002015 obo:IAO_0000115 "A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B." ; oboInOwl:created_by ; oboInOwl:creation_date "2017-05-24T09:31:17Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:comment "By convention GO molecular functions are classified by their effector function and internal regulatory functions are treated as components. So, for example calmodulin has a protein binding activity that has positive regulatory component activity calcium binding activity. Receptor tyrosine kinase activity is a tyrosine kinase activity that has positive regulatory component 'ligand binding'." ; rdfs:label "has positive regulatory component activity" ; rdfs:subPropertyOf obo:RO_0002013, obo:RO_0002336 . obo:RO_0002017 oboInOwl:created_by ; oboInOwl:creation_date "2017-05-24T09:44:33Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:comment "A 'has component activity' B if A is A and B are molecular functions (GO_0003674) and A has_component B." ; rdfs:label "has component activity" ; rdfs:subPropertyOf obo:RO_0002018 . obo:RO_0002018 obo:IAO_0000115 "w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ; oboInOwl:created_by ; oboInOwl:creation_date "2017-05-24T09:49:21Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000015 ; rdfs:label "has component process" ; rdfs:range obo:BFO_0000015 ; rdfs:subPropertyOf obo:RO_0002180 . obo:RO_0002022 oboInOwl:created_by ; oboInOwl:creation_date "2017-09-17T13:52:24Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:comment "Process(P2) is directly regulated by process(P1) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding regulates the kinase activity (P2) of protein B then P1 directly regulates P2." ; rdfs:label "directly regulated by" ; rdfs:subPropertyOf obo:RO_0002334 ; owl:inverseOf obo:RO_0002578 . obo:RO_0002023 obo:IAO_0000115 "Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1." ; oboInOwl:created_by ; oboInOwl:creation_date "2017-09-17T13:52:38Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:label "directly negatively regulated by" ; rdfs:subPropertyOf obo:RO_0002022 ; owl:inverseOf obo:RO_0002630 . obo:RO_0002024 obo:IAO_0000115 "Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1." ; oboInOwl:created_by ; oboInOwl:creation_date "2017-09-17T13:52:47Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:label "directly positively regulated by" ; rdfs:subPropertyOf obo:RO_0002022 ; owl:inverseOf obo:RO_0002629 . obo:RO_0002025 obo:IAO_0000115 "A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity." ; oboInOwl:created_by ; oboInOwl:creation_date "2017-09-22T14:14:36Z"^^xsd:dateTime ; a owl:FunctionalProperty, owl:ObjectProperty ; rdfs:comment "This relation is designed for constructing compound molecular functions, typically in combination with one or more regulatory component activity relations." ; rdfs:label "has effector activity" ; rdfs:subPropertyOf obo:RO_0002017 . obo:RO_0002086 obo:IAO_0000117 "David Osumi-Sutherland" ; oboInOwl:inSubset subsets:ro-eco ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:comment "X ends_after Y iff: end(Y) before_or_simultaneous_with end(X)"@en ; rdfs:label "ends after"@en ; rdfs:subPropertyOf obo:RO_0002222 . obo:RO_0002087 obo:IAO_0000117 "David Osumi-Sutherland" ; obo:IAO_0000118 "starts_at_end_of" ; oboInOwl:hasDbXref "RO:0002087" ; oboInOwl:hasOBONamespace "worm_development" ; oboInOwl:id "starts_at_end_of" ; oboInOwl:shorthand "starts_at_end_of" ; a owl:ObjectProperty ; rdfs:comment "X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y)"@en ; rdfs:label "immediately preceded by"@en, "starts_at_end_of" ; rdfs:subPropertyOf obo:BFO_0000062 ; owl:inverseOf obo:RO_0002090 . obo:RO_0002090 obo:IAO_0000117 , "David Osumi-Sutherland" ; obo:IAO_0000118 "ends_at_start_of", "meets" ; obo:RO_0002575 obo:BFO_0000063 ; oboInOwl:inSubset subsets:ro-eco ; a owl:ObjectProperty ; rdfs:comment "X immediately_precedes_Y iff: end(X) simultaneous_with start(Y)"@en ; rdfs:label "immediately precedes"@en ; rdfs:subPropertyOf obo:BFO_0000063 . obo:RO_0002092 oboInOwl:hasDbXref "RO:0002092" ; oboInOwl:hasOBONamespace "external" ; oboInOwl:id "happens_during" ; oboInOwl:shorthand "happens_during" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "happens during" ; rdfs:subPropertyOf obo:RO_0002093 . obo:RO_0002093 oboInOwl:hasDbXref "RO:0002093" ; oboInOwl:hasOBONamespace "external" ; oboInOwl:id "ends_during" ; oboInOwl:shorthand "ends_during" ; a owl:ObjectProperty ; rdfs:label "ends during" . obo:RO_0002131 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "x overlaps y if and only if there exists some z such that x has part z and z part of y" ; obo:IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)" ; obo:RO_0001900 obo:RO_0001901 ; oboInOwl:inSubset subsets:ro-eco, obo:valid_for_go_annotation_extension, obo:valid_for_gocam ; a owl:ObjectProperty, owl:SymmetricProperty ; rdfs:label "overlaps"@en ; rdfs:subPropertyOf obo:RO_0002323 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:BFO_0000050 ), (obo:BFO_0000051 obo:BFO_0000050 ), (obo:BFO_0000051 obo:RO_0002131 ), (obo:RO_0002131 obo:BFO_0000050 ) . obo:RO_0002160 a owl:ObjectProperty . obo:RO_0002161 a owl:AnnotationProperty . obo:RO_0002162 a owl:ObjectProperty . obo:RO_0002175 a owl:AnnotationProperty . obo:RO_0002180 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type." ; obo:IAO_0000116 "The definition of 'has component' is still under discussion. The challenge is in providing a definition that does not imply transitivity." ; obo:IAO_0000232 "For use in recording has_part with a cardinality constraint, because OWL does not permit cardinality constraints to be used in combination with transitive object properties. In situations where you would want to say something like 'has part exactly 5 digit, you would instead use has_component exactly 5 digit."@en ; obo:RO_0001900 obo:RO_0001901 ; oboInOwl:inSubset subsets:ro-eco ; a owl:ObjectProperty ; rdfs:label "has component"@en ; rdfs:seeAlso ; rdfs:subPropertyOf obo:BFO_0000051 . obo:RO_0002202 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y" ; obo:IAO_0000117 , , , ; oboInOwl:hasDbXref "RO:0002202" ; oboInOwl:hasOBONamespace "worm_anatomy" ; oboInOwl:id "develops_from" ; oboInOwl:shorthand "develops_from" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:comment "This is the transitive form of the develops from relation" ; rdfs:domain obo:BFO_0000004 ; rdfs:label "develops from"@en, "develops_from" ; rdfs:range obo:BFO_0000004 ; rdfs:subPropertyOf obo:RO_0002258 ; owl:inverseOf obo:RO_0002203 . obo:RO_0002203 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "inverse of develops from" ; obo:IAO_0000117 , , ; oboInOwl:inSubset obo:RO_0002259 ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "develops into"@en ; rdfs:subPropertyOf obo:RO_0002286, obo:RO_0002387, obo:RO_0002388 . obo:RO_0002211 obo:IAO_0000115 "p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q." ; obo:IAO_0000117 , , ; obo:IAO_0000119 , "GO" ; obo:IAO_0000232 "Regulation precludes parthood; the regulatory process may not be within the regulated process." ; obo:IAO_0000589 "regulates (processual)" ; obo:IAO_0000600 false ; oboInOwl:hasDbXref "RO:0002211" ; oboInOwl:hasOBONamespace "external" ; oboInOwl:id "regulates" ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; oboInOwl:shorthand "regulates" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:domain obo:BFO_0000015 ; rdfs:label "regulates", "regulates"@en ; rdfs:range obo:BFO_0000015 ; rdfs:subPropertyOf obo:RO_0002411 ; owl:inverseOf obo:RO_0002334 ; owl:propertyChainAxiom (obo:RO_0002211 obo:RO_0002025 ), (obo:RO_0002578 obo:RO_0002578 ) . obo:RO_0002212 obo:IAO_0000115 "p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q." ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000589 "negatively regulates (process to process)" ; obo:RO_0004050 obo:RO_0002211 ; oboInOwl:hasDbXref "RO:0002212" ; oboInOwl:hasOBONamespace "external" ; oboInOwl:id "negatively_regulates" ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; oboInOwl:shorthand "negatively_regulates" ; a owl:ObjectProperty ; rdfs:label "negatively regulates", "negatively regulates"@en ; rdfs:subPropertyOf obo:RO_0002211, obo:RO_0002305 ; owl:inverseOf obo:RO_0002335 . obo:RO_0002213 obo:IAO_0000115 "p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q." ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000589 "positively regulates (process to process)" ; obo:RO_0004049 obo:RO_0002211 ; oboInOwl:hasDbXref "RO:0002213" ; oboInOwl:hasOBONamespace "external" ; oboInOwl:id "positively_regulates" ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; oboInOwl:shorthand "positively_regulates" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "positively regulates", "positively regulates"@en ; rdfs:subPropertyOf obo:RO_0002211, obo:RO_0002304 ; owl:inverseOf obo:RO_0002336 ; owl:propertyChainAxiom (obo:RO_0002212 obo:RO_0002212 ) . obo:RO_0002215 obo:IAO_0000112 "mechanosensory neuron capable of detection of mechanical stimulus involved in sensory perception (GO:0050974)", "osteoclast SubClassOf 'capable of' some 'bone resorption'" ; obo:IAO_0000115 "A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. " ; obo:IAO_0000117 ; obo:IAO_0000118 "has function realized in" ; obo:IAO_0000119 , ; obo:IAO_0000232 "For compatibility with BFO, this relation has a shortcut definition in which the expression \"capable of some P\" expands to \"bearer_of (some realized_by only P)\"." ; oboInOwl:inSubset subsets:ro-eco ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000004 ; rdfs:label "capable of"@en ; rdfs:range obo:BFO_0000015 ; rdfs:subPropertyOf obo:RO_0002216 . obo:RO_0002216 obo:IAO_0000115 "c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p." ; obo:IAO_0000117 ; obo:IAO_0000118 "has function in" ; a owl:ObjectProperty ; rdfs:label "capable of part of"@en ; rdfs:seeAlso ; rdfs:subPropertyOf obo:RO_0002328, obo:RO_0002500 ; owl:propertyChainAxiom (obo:RO_0002215 obo:BFO_0000050 ) . obo:RO_0002222 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000232 "Do not use this relation directly. It is ended as a grouping for relations between occurrents involving the relative timing of their starts and ends." ; terms:source "https://docs.google.com/document/d/1kBv1ep_9g3sTR-SD3jqzFqhuwo9TPNF-l-9fUDbO6rM/edit?pli=1"^^xsd:anyURI ; oboInOwl:inSubset subsets:ro-eco ; a owl:ObjectProperty ; rdfs:comment "A relation that holds between two occurrents. This is a grouping relation that collects together all the Allen relations." ; rdfs:domain obo:BFO_0000003 ; rdfs:label "temporally related to"@en ; rdfs:range obo:BFO_0000003 . obo:RO_0002233 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p." ; obo:IAO_0000117 ; obo:IAO_0000118 "consumes" ; oboInOwl:inSubset subsets:ro-eco, obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000015 ; rdfs:label "has input"@en ; rdfs:seeAlso "https://wiki.geneontology.org/Has_input"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0000057 ; owl:inverseOf obo:RO_0002352 . obo:RO_0002254 obo:IAO_0000112 "Mammalian thymus has developmental contribution from some pharyngeal pouch 3; Mammalian thymus has developmental contribution from some pharyngeal pouch 4 [Kardong]" ; obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "x has developmental contribution from y iff x has some part z such that z develops from y"@en ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:domain obo:UBERON_0001062 ; rdfs:label "has developmental contribution from"@en ; rdfs:range obo:UBERON_0001062 ; rdfs:subPropertyOf obo:RO_0002258 ; owl:inverseOf obo:RO_0002255 ; owl:propertyChainAxiom (obo:BFO_0000051 obo:RO_0002202 ) . obo:RO_0002255 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "inverse of has developmental contribution from" ; obo:IAO_0000117 ; oboInOwl:inSubset obo:RO_0002259 ; a owl:ObjectProperty ; rdfs:label "developmentally contributes to"@en ; rdfs:subPropertyOf obo:RO_0002286, obo:RO_0002385 ; owl:propertyChainAxiom (obo:RO_0002203 obo:BFO_0000050 ) . obo:RO_0002258 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p" ; obo:IAO_0000116 false ; obo:IAO_0000117 ; obo:IAO_0000232 "In general you should not use this relation to make assertions - use one of the more specific relations below this one" ; a owl:ObjectProperty ; rdfs:comment "This relation groups together various other developmental relations. It is fairly generic, encompassing induction, developmental contribution and direct and transitive develops from" ; rdfs:domain obo:BFO_0000002 ; rdfs:label "developmentally preceded by"@en ; rdfs:range obo:BFO_0000002 ; rdfs:subPropertyOf obo:RO_0002324 ; owl:inverseOf obo:RO_0002286 . obo:RO_0002259 a owl:AnnotationProperty ; rdfs:subPropertyOf oboInOwl:SubsetProperty . obo:RO_0002263 obo:IAO_0000112 "A faulty traffic light (material entity) whose malfunctioning (a process) is causally upstream of a traffic collision (a process): the traffic light acts upstream of the collision." ; obo:IAO_0000115 "c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes." ; oboInOwl:inSubset obo:valid_for_go_gp2term ; a owl:ObjectProperty ; rdfs:label "acts upstream of" ; rdfs:seeAlso ; rdfs:subPropertyOf obo:RO_0002264 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002411 ) . obo:RO_0002264 obo:IAO_0000112 "A gene product that has some activity, where that activity may be a part of a pathway or upstream of the pathway." ; obo:IAO_0000115 "c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process." ; oboInOwl:hasRelatedSynonym "affects" ; oboInOwl:inSubset obo:valid_for_go_gp2term ; a owl:ObjectProperty ; rdfs:label "acts upstream of or within" ; rdfs:seeAlso "https://wiki.geneontology.org/Acts_upstream_of_or_within"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002500 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002418 ) . obo:RO_0002286 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "Inverse of developmentally preceded by" ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "developmentally succeeded by"@en ; rdfs:subPropertyOf obo:RO_0002384 . obo:RO_0002295 obo:IAO_0000114 obo:IAO_0000125 ; obo:IAO_0000115 "p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss)." ; obo:IAO_0000116 "This property and its subproperties are being used primarily for the definition of GO developmental processes. The property hierarchy mirrors the core GO hierarchy. In future we may be able to make do with a more minimal set of properties, but due to the way GO is currently structured we require highly specific relations to avoid incorrect entailments. To avoid this, the corresponding genus terms in GO should be declared mutually disjoint." ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:domain obo:GO_0008150 ; rdfs:label "results in developmental progression of"@en ; rdfs:range obo:UBERON_0001062 ; rdfs:seeAlso ; rdfs:subPropertyOf obo:RO_0002324 . obo:RO_0002304 obo:IAO_0000115 "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q." ; obo:RO_0004049 obo:RO_0002411 ; terms:creator ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_gocam ; a owl:ObjectProperty ; rdfs:comment "holds between x and y if and only if x is causally upstream of y and the progression of x increases the frequency, rate or extent of y" ; rdfs:label "causally upstream of, positive effect" ; rdfs:seeAlso ; rdfs:subPropertyOf obo:RO_0002411, obo:RO_0004047 . obo:RO_0002305 obo:IAO_0000115 "p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q." ; obo:RO_0004050 obo:RO_0002411 ; terms:creator ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_gocam ; a owl:ObjectProperty ; rdfs:label "causally upstream of, negative effect" ; rdfs:seeAlso ; rdfs:subPropertyOf obo:RO_0002411, obo:RO_0004046 . obo:RO_0002314 obo:IAO_0000115 "q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w." ; obo:IAO_0000116 "Because part_of is transitive, inheres in is a sub-relation of characteristic of part of" ; obo:IAO_0000117 ; obo:IAO_0000118 "inheres in part of" ; obo:IAO_0000119 ; obo:RO_0001900 obo:RO_0001901 ; a owl:ObjectProperty ; rdfs:label "characteristic of part of"@en ; rdfs:seeAlso ; rdfs:subPropertyOf obo:RO_0002502 ; owl:propertyChainAxiom (obo:RO_0000052 obo:BFO_0000050 ), (obo:RO_0000052 obo:BFO_0000050 ), (obo:RO_0002314 obo:BFO_0000050 ) . obo:RO_0002323 obo:IAO_0000115 "A mereological relationship or a topological relationship" ; obo:IAO_0000117 ; obo:IAO_0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving parthood or connectivity relationships" ; obo:RO_0001900 obo:RO_0001901 ; a owl:ObjectProperty ; rdfs:label "mereotopologically related to"@en . obo:RO_0002324 obo:IAO_0000115 "A relationship that holds between entities participating in some developmental process (GO:0032502)" ; obo:IAO_0000117 ; obo:IAO_0000232 "Do not use this relation directly. It is ended as a grouping for a diverse set of relations, all involving organismal development" ; a owl:ObjectProperty ; rdfs:label "developmentally related to"@en . obo:RO_0002327 obo:IAO_0000112 "a particular instances of akt-2 enables some instance of protein kinase activity" ; obo:IAO_0000115 "c enables p iff c is capable of p and c acts to execute p." ; obo:IAO_0000117 ; obo:IAO_0000118 "catalyzes", "executes", "has", "is catalyzing", "is executing" ; obo:IAO_0000232 "This relation differs from the parent relation 'capable of' in that the parent is weaker and only expresses a capability that may not be actually realized, whereas this relation is always realized." ; oboInOwl:inSubset obo:valid_for_go_gp2term ; a owl:ObjectProperty ; rdfs:label "enables"@en ; rdfs:seeAlso "https://wiki.geneontology.org/Enables"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002215 ; owl:inverseOf obo:RO_0002333 ; owl:propertyChainAxiom (obo:RO_0002327 obo:BFO_0000051 ), (obo:RO_0002327 obo:RO_0002017 ) . obo:RO_0002328 obo:IAO_0000115 "A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities." ; obo:IAO_0000117 ; obo:IAO_0000232 "This is a grouping relation that collects relations used for the purpose of connecting structure and function" ; a owl:ObjectProperty ; rdfs:label "functionally related to"@en . obo:RO_0002329 obo:IAO_0000115 "this relation holds between c and p when c is part of some c', and c' is capable of p." ; obo:IAO_0000117 ; obo:IAO_0000118 false ; a owl:ObjectProperty ; rdfs:label "part of structure that is capable of"@en ; rdfs:subPropertyOf obo:RO_0002328 ; owl:propertyChainAxiom (obo:BFO_0000050 obo:RO_0002215 ) . obo:RO_0002331 obo:IAO_0000115 "c involved_in p if and only if c enables some process p', and p' is part of p" ; obo:IAO_0000117 ; obo:IAO_0000118 "actively involved in", "enables part of" ; a owl:ObjectProperty ; rdfs:label "involved in"@en ; rdfs:seeAlso "https://wiki.geneontology.org/Involved_in"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0000056, obo:RO_0002431 ; owl:propertyChainAxiom (obo:RO_0002327 obo:BFO_0000050 ), (obo:RO_0002331 obo:BFO_0000050 ) . obo:RO_0002333 obo:IAO_0000115 "inverse of enables" ; obo:IAO_0000117 ; oboInOwl:inSubset obo:valid_for_gocam ; a owl:ObjectProperty ; rdfs:label "enabled by"@en ; rdfs:seeAlso "https://wiki.geneontology.org/Enabled_by"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0000057, obo:RO_0002328 . obo:RO_0002334 obo:IAO_0000115 "inverse of regulates" ; obo:IAO_0000117 ; obo:IAO_0000589 "regulated by (processual)" ; oboInOwl:inSubset obo:RO_0002259 ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:domain obo:BFO_0000015 ; rdfs:label "regulated by"@en ; rdfs:range obo:BFO_0000015 ; rdfs:subPropertyOf obo:RO_0002427 . obo:RO_0002335 obo:IAO_0000115 "inverse of negatively regulates" ; obo:IAO_0000117 ; oboInOwl:inSubset obo:RO_0002259 ; a owl:ObjectProperty ; rdfs:label "negatively regulated by"@en ; rdfs:subPropertyOf obo:RO_0002334 . obo:RO_0002336 obo:IAO_0000115 "inverse of positively regulates" ; obo:IAO_0000117 ; oboInOwl:inSubset obo:RO_0002259 ; a owl:ObjectProperty ; rdfs:label "positively regulated by"@en ; rdfs:subPropertyOf obo:RO_0002334 . obo:RO_0002352 obo:IAO_0000115 "inverse of has input" ; obo:IAO_0000117 ; oboInOwl:inSubset obo:RO_0002259, subsets:ro-eco ; a owl:ObjectProperty ; rdfs:label "input of"@en ; rdfs:subPropertyOf obo:RO_0000056, obo:RO_0002328 . obo:RO_0002384 obo:IAO_0000114 obo:IAO_0000428 ; obo:IAO_0000115 "x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction)."@en ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:domain obo:UBERON_0001062 ; rdfs:label "has developmental potential involving"@en ; rdfs:range obo:UBERON_0001062 ; rdfs:subPropertyOf obo:RO_0002324 . obo:RO_0002385 obo:IAO_0000114 obo:IAO_0000428 ; obo:IAO_0000115 "x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y"@en ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "has potential to developmentally contribute to"@en ; rdfs:subPropertyOf obo:RO_0002384 . obo:RO_0002387 obo:IAO_0000114 obo:IAO_0000428 ; obo:IAO_0000115 "x has the potential to develop into y iff x develops into y or if x is capable of developing into y"@en ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "has potential to develop into"@en ; rdfs:subPropertyOf obo:RO_0002384 . obo:RO_0002388 obo:IAO_0000114 obo:IAO_0000428 ; obo:IAO_0000115 "x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y"@en ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "has potential to directly develop into"@en ; rdfs:subPropertyOf obo:RO_0002387 . obo:RO_0002404 obo:IAO_0000114 obo:IAO_0000428 ; obo:IAO_0000115 "inverse of upstream of" ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "causally downstream of"@en ; rdfs:subPropertyOf obo:BFO_0000062, obo:RO_0002427 ; owl:inverseOf obo:RO_0002411 . obo:RO_0002405 obo:IAO_0000114 obo:IAO_0000428 ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "immediately causally downstream of"@en ; rdfs:subPropertyOf obo:RO_0002087, obo:RO_0002404 ; owl:inverseOf obo:RO_0002412 . obo:RO_0002407 obo:IAO_0000115 "p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q." ; obo:IAO_0000117 ; obo:IAO_0000118 "indirectly activates" ; obo:RO_0002579 obo:RO_0002213 ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "indirectly positively regulates"@en ; rdfs:seeAlso "https://wiki.geneontology.org/Indirectly_positively_regulates"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002213, obo:RO_0012012 ; owl:propertyChainAxiom (obo:RO_0002407 obo:RO_0002629 ), (obo:RO_0002409 obo:RO_0002409 ), (obo:RO_0002629 obo:RO_0002407 ), (obo:RO_0002629 obo:RO_0002629 ) . obo:RO_0002409 obo:IAO_0000115 "p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q." ; obo:IAO_0000117 ; obo:IAO_0000118 "indirectly inhibits" ; obo:RO_0002579 obo:RO_0002212 ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "indirectly negatively regulates"@en ; rdfs:seeAlso "https://wiki.geneontology.org/Indirectly_negatively_regulates"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002212, obo:RO_0012012 ; owl:propertyChainAxiom (obo:RO_0002409 obo:RO_0002630 ), (obo:RO_0002630 obo:RO_0002409 ), (obo:RO_0002630 obo:RO_0002630 ) . obo:RO_0002410 obo:IAO_0000115 "relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause." ; obo:IAO_0000116 """This branch of the ontology deals with causal relations between entities. It is divided into two branches: causal relations between occurrents/processes, and causal relations between material entities. We take an 'activity flow-centric approach', with the former as primary, and define causal relations between material entities in terms of causal relations between occurrents. To define causal relations in an activity-flow type network, we make use of 3 primitives: * Temporal: how do the intervals of the two occurrents relate? * Is the causal relation regulatory? * Is the influence positive or negative? The first of these can be formalized in terms of the Allen Interval Algebra. Informally, the 3 bins we care about are 'direct', 'indirect' or overlapping. Note that all causal relations should be classified under a RO temporal relation (see the branch under 'temporally related to'). Note that all causal relations are temporal, but not all temporal relations are causal. Two occurrents can be related in time without being causally connected. We take causal influence to be primitive, elucidated as being such that has the upstream changed, some qualities of the donwstream would necessarily be modified. For the second, we consider a relationship to be regulatory if the system in which the activities occur is capable of altering the relationship to achieve some objective. This could include changing the rate of production of a molecule. For the third, we consider the effect of the upstream process on the output(s) of the downstream process. If the level of output is increased, or the rate of production of the output is increased, then the direction is increased. Direction can be positive, negative or neutral or capable of either direction. Two positives in succession yield a positive, two negatives in succession yield a positive, otherwise the default assumption is that the net effect is canceled and the influence is neutral. Each of these 3 primitives can be composed to yield a cross-product of different relation types.""" ; obo:IAO_0000117 ; obo:IAO_0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." ; a owl:ObjectProperty ; rdfs:label "causally related to"@en . obo:RO_0002411 obo:IAO_0000115 "p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q." ; obo:IAO_0000117 ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_gocam ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "causally upstream of"@en ; rdfs:subPropertyOf obo:BFO_0000063, obo:RO_0002418 . obo:RO_0002412 obo:IAO_0000115 "p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q." ; obo:IAO_0000117 ; obo:RO_0002575 obo:RO_0002411 ; a owl:ObjectProperty ; rdfs:label "immediately causally upstream of"@en ; rdfs:subPropertyOf obo:RO_0002090, obo:RO_0002411 . obo:RO_0002418 obo:IAO_0000115 "p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q." ; obo:IAO_0000116 "We would like to make this disjoint with 'preceded by', but this is prohibited in OWL2" ; obo:IAO_0000117 ; obo:IAO_0000118 "influences (processual)" ; oboInOwl:hasRelatedSynonym "affects" ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "causally upstream of or within" ; rdfs:subPropertyOf obo:RO_0002501 ; owl:inverseOf obo:RO_0002427 . obo:RO_0002427 obo:IAO_0000115 "inverse of causally upstream of or within" ; obo:IAO_0000117 ; obo:IAO_0000119 ; oboInOwl:inSubset obo:RO_0002259 ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "causally downstream of or within" ; rdfs:subPropertyOf obo:RO_0002501 . obo:RO_0002428 obo:IAO_0000115 "c involved in regulation of p if c is involved in some p' and p' regulates some p" ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "involved in regulation of" ; rdfs:subPropertyOf obo:RO_0002263, obo:RO_0002431 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002211 ), (obo:RO_0002331 obo:RO_0002211 ) . obo:RO_0002429 obo:IAO_0000115 "c involved in regulation of p if c is involved in some p' and p' positively regulates some p" ; obo:IAO_0000117 ; obo:RO_0004049 obo:RO_0002428 ; a owl:ObjectProperty ; rdfs:label "involved in positive regulation of" ; rdfs:subPropertyOf obo:RO_0002428 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002213 ), (obo:RO_0002331 obo:RO_0002213 ) . obo:RO_0002430 obo:IAO_0000115 "c involved in regulation of p if c is involved in some p' and p' negatively regulates some p" ; obo:IAO_0000117 ; obo:RO_0004050 obo:RO_0002428 ; a owl:ObjectProperty ; rdfs:label "involved in negative regulation of" ; rdfs:subPropertyOf obo:RO_0002428 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002212 ), (obo:RO_0002331 obo:RO_0002212 ) . obo:RO_0002431 obo:IAO_0000115 "c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p" ; obo:IAO_0000116 "OWL does not allow defining object properties via a Union" ; obo:IAO_0000117 ; obo:IAO_0000118 "involved in or reguates" ; a owl:ObjectProperty ; rdfs:label "involved in or involved in regulation of" ; rdfs:subPropertyOf obo:RO_0002264, obo:RO_0002328, obo:RO_0002500 . obo:RO_0002432 obo:IAO_0000112 "A protein that enables activity in a cytosol." ; obo:IAO_0000115 "c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure." ; obo:IAO_0000117 ; obo:IAO_0000118 "executes activity in" ; oboInOwl:hasExactSynonym "enables activity in" ; a owl:ObjectProperty ; rdfs:comment "" ; rdfs:label "is active in" ; rdfs:seeAlso "https://wiki.geneontology.org/Is_active_in"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002131, obo:RO_0002328 ; owl:propertyChainAxiom (obo:RO_0002327 obo:BFO_0000066 ) . obo:RO_0002434 obo:IAO_0000115 "A relationship that holds between two entities in which the processes executed by the two entities are causally connected." ; obo:IAO_0000116 "Considering relabeling as 'pairwise interacts with'"^^xsd:anyURI, "This relation and all sub-relations can be applied to either (1) pairs of entities that are interacting at any moment of time (2) populations or species of entity whose members have the disposition to interact (3) classes whose members have the disposition to interact." ; obo:IAO_0000117 ; obo:IAO_0000232 "Note that this relationship type, and sub-relationship types may be redundant with process terms from other ontologies. For example, the symbiotic relationship hierarchy parallels GO. The relations are provided as a convenient shortcut. Consider using the more expressive processual form to capture your data. In the future, these relations will be linked to their cognate processes through rules." ; oboInOwl:hasExactSynonym "in pairwise interaction with" ; oboInOwl:inSubset subsets:ro-eco ; a owl:ObjectProperty, owl:SymmetricProperty ; rdfs:domain obo:BFO_0000040 ; rdfs:label "interacts with" ; rdfs:range obo:BFO_0000040 ; rdfs:seeAlso "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/"^^xsd:anyURI ; skos:closeMatch "http://purl.obolibrary.org/obo/MI_0914"^^xsd:anyURI . obo:RO_0002436 obo:IAO_0000115 "An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other." ; obo:IAO_0000117 ; obo:IAO_0000118 "binds", "molecularly binds with" ; a owl:ObjectProperty, owl:SymmetricProperty ; rdfs:label "molecularly interacts with" ; rdfs:seeAlso obo:ECO_0000353 ; rdfs:subPropertyOf obo:RO_0002434 ; skos:closeMatch "http://purl.obolibrary.org/obo/MI_0915"^^xsd:anyURI . obo:RO_0002447 obo:IAO_0000116 "Axiomatization to GO to be added later" ; obo:IAO_0000117 ; obo:IAO_0000118 "An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y." ; a owl:ObjectProperty ; rdfs:label "phosphorylates" ; rdfs:subPropertyOf obo:RO_0002436 . obo:RO_0002448 obo:IAO_0000115 """The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.""" ; obo:IAO_0000117 , ; oboInOwl:hasExactSynonym "molecularly controls" ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000040 ; rdfs:label "directly regulates activity of" ; rdfs:range obo:BFO_0000040 ; rdfs:subPropertyOf obo:RO_0002436, obo:RO_0011002 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002211 obo:RO_0002333 ) . obo:RO_0002449 obo:IAO_0000115 """The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.""" ; obo:IAO_0000117 , ; obo:IAO_0000118 "directly inhibits" ; oboInOwl:hasExactSynonym "molecularly decreases activity of" ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000040 ; rdfs:label "directly negatively regulates activity of" ; rdfs:range obo:BFO_0000040 ; rdfs:subPropertyOf obo:RO_0002448 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002630 obo:RO_0002333 ) . obo:RO_0002450 obo:IAO_0000115 """The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.""" ; obo:IAO_0000117 , ; obo:IAO_0000118 "directly activates" ; oboInOwl:hasExactSynonym "molecularly increases activity of" ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000040 ; rdfs:label "directly positively regulates activity of" ; rdfs:range obo:BFO_0000040 ; rdfs:subPropertyOf obo:RO_0002448 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002629 obo:RO_0002333 ) . obo:RO_0002464 obo:IAO_0000117 ; obo:IAO_0000232 "This property or its subproperties is not to be used directly. These properties exist as helper properties that are used to support OWL reasoning." ; a owl:ObjectProperty ; rdfs:label "helper property (not for use in curation)" . obo:RO_0002479 obo:IAO_0000115 "p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c." ; obo:IAO_0000117 ; oboInOwl:inSubset subsets:ro-eco ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "has part that occurs in" ; rdfs:range obo:BFO_0000004 ; owl:propertyChainAxiom (obo:BFO_0000051 obo:BFO_0000066 ) . obo:RO_0002481 obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "is kinase activity" ; rdfs:subPropertyOf obo:RO_0002564 . obo:RO_0002500 obo:IAO_0000115 "A relationship between a material entity and a process where the material entity has some causal role that influences the process" ; obo:IAO_0000119 ; a owl:ObjectProperty ; rdfs:label "causal agent in process" ; rdfs:subPropertyOf obo:RO_0002595 ; owl:inverseOf obo:RO_0002608 . obo:RO_0002501 obo:IAO_0000115 "p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q." ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000003 ; rdfs:label "causal relation between processes" ; rdfs:range obo:BFO_0000003 ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0002502 obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "depends on" ; rdfs:seeAlso obo:BFO_0000169 . obo:RO_0002503 obo:IAO_0000115 "q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2" ; obo:IAO_0000116 "This relation is provided in order to support the use of relational qualities such as 'concentration of'; for example, the concentration of C in V is a quality that inheres in V, but pertains to C." ; obo:IAO_0000117 ; obo:IAO_0000119 ; a owl:ObjectProperty ; rdfs:label "towards" ; rdfs:subPropertyOf obo:RO_0002502 . obo:RO_0002506 obo:IAO_0000116 "The intent is that the process branch of the causal property hierarchy is primary (causal relations hold between occurrents/processes), and that the material branch is defined in terms of the process branch" ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000232 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000002 ; rdfs:label "causal relation between entities" ; rdfs:range obo:BFO_0000002 ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0002559 obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000589 "causally influenced by (entity-centric)" ; a owl:ObjectProperty ; rdfs:label "causally influenced by" ; rdfs:subPropertyOf obo:RO_0002506 ; owl:inverseOf obo:RO_0002566 . obo:RO_0002563 obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "interaction relation helper property" ; rdfs:seeAlso , "http://purl.obolibrary.org/obo/ro/docs/interaction-relations/"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002464 . obo:RO_0002564 obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "molecular interaction relation helper property" ; rdfs:subPropertyOf obo:RO_0002563 . obo:RO_0002566 obo:IAO_0000115 "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size)." ; obo:IAO_0000117 , ; obo:IAO_0000119 ; obo:IAO_0000589 "causally influences (entity-centric)" ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000002 ; rdfs:label "causally influences" ; rdfs:range obo:BFO_0000002 ; rdfs:subPropertyOf obo:RO_0002506 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002411 obo:RO_0002233 ), (obo:RO_0002327 obo:RO_0002411 obo:RO_0002333 ) . obo:RO_0002573 obo:IAO_0000115 "A relation that holds between an attribute or a qualifier and another attribute." ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000232 "This relation is intended to be used in combination with PATO, to be able to refine PATO quality classes using modifiers such as 'abnormal' and 'normal'. It has yet to be formally aligned into an ontological framework; it's not clear what the ontological status of the \"modifiers\" are." ; oboInOwl:inSubset subsets:ro-eco ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000020 ; rdfs:label "has modifier" ; rdfs:range obo:BFO_0000020 . obo:RO_0002575 a owl:AnnotationProperty . obo:RO_0002578 obo:IAO_0000115 "p directly regulates q iff p is immediately causally upstream of q and p regulates q." ; obo:IAO_0000117 ; obo:IAO_0000119 ; obo:IAO_0000589 "directly regulates (processual)" ; obo:RO_0002575 obo:RO_0002211 ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; a owl:ObjectProperty ; rdfs:label "directly regulates" ; rdfs:subPropertyOf obo:RO_0002211, obo:RO_0002412 . obo:RO_0002579 a owl:AnnotationProperty . obo:RO_0002581 obo:IAO_0000115 "If R <- P o Q is a defining property chain axiom, then it also holds that R -> P o Q. Note that this cannot be expressed directly in OWL" ; a owl:AnnotationProperty ; rdfs:label "is a defining property chain axiom" . obo:RO_0002582 obo:IAO_0000115 "If R <- P o Q is a defining property chain axiom, then (1) R -> P o Q holds and (2) Q is either reflexive or locally reflexive. A corollary of this is that P SubPropertyOf R." ; a owl:AnnotationProperty ; rdfs:label "is a defining property chain axiom where second argument is reflexive" . obo:RO_0002584 obo:IAO_0000112 "gland SubClassOf 'has part structure that is capable of' some 'secretion by cell'" ; obo:IAO_0000115 "s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p" ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:label "has part structure that is capable of" ; rdfs:subPropertyOf obo:RO_0002328, obo:RO_0002595 ; owl:propertyChainAxiom (obo:BFO_0000051 obo:RO_0002215 ) . obo:RO_0002595 obo:IAO_0000115 "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity." ; obo:IAO_0000116 "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving cause and effect." ; obo:IAO_0000117 ; obo:IAO_0000119 ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000040 ; rdfs:label "causal relation between material entity and a process" ; rdfs:range obo:BFO_0000015 ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0002596 obo:IAO_0000112 "pyrethroid -> growth" ; obo:IAO_0000115 "Holds between c and p if and only if c is capable of some activity a, and a regulates p." ; obo:IAO_0000119 ; a owl:ObjectProperty ; rdfs:label "capable of regulating" ; rdfs:subPropertyOf obo:RO_0002500 ; owl:propertyChainAxiom (obo:RO_0002215 obo:RO_0002211 ) . obo:RO_0002597 obo:IAO_0000115 "Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p." ; obo:IAO_0000119 ; a owl:ObjectProperty ; rdfs:label "capable of negatively regulating" ; rdfs:subPropertyOf obo:RO_0002596 ; owl:propertyChainAxiom (obo:RO_0002215 obo:RO_0002212 ) . obo:RO_0002598 obo:IAO_0000112 "renin -> arteriolar smooth muscle contraction" ; obo:IAO_0000115 "Holds between c and p if and only if c is capable of some activity a, and a positively regulates p." ; obo:IAO_0000119 ; a owl:ObjectProperty ; rdfs:label "capable of positively regulating" ; rdfs:subPropertyOf obo:RO_0002596 ; owl:propertyChainAxiom (obo:RO_0002215 obo:RO_0002213 ) . obo:RO_0002604 a owl:AnnotationProperty . obo:RO_0002608 obo:IAO_0000115 "Inverse of 'causal agent in process'" ; obo:IAO_0000119 ; a owl:ObjectProperty ; rdfs:label "process has causal agent" ; rdfs:subPropertyOf obo:RO_0002410 . obo:RO_0002610 a owl:ObjectProperty . obo:RO_0002629 obo:IAO_0000115 "p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q." ; obo:IAO_0000119 ; obo:IAO_0000589 "directly positively regulates (process to process)" ; obo:RO_0004049 obo:RO_0002578 ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; a owl:ObjectProperty ; rdfs:label "directly positively regulates" ; rdfs:seeAlso "https://wiki.geneontology.org/Directly_positively_regulates"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002213, obo:RO_0002578 . obo:RO_0002630 obo:IAO_0000115 "p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q." ; obo:IAO_0000119 ; obo:IAO_0000589 "directly negatively regulates (process to process)" ; obo:RO_0004050 obo:RO_0002578 ; oboInOwl:inSubset obo:valid_for_go_annotation_extension, obo:valid_for_go_ontology, obo:valid_for_gocam ; a owl:ObjectProperty ; rdfs:label "directly negatively regulates" ; rdfs:seeAlso "https://wiki.geneontology.org/Directly_negatively_regulates"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002212, obo:RO_0002578 . obo:RO_0004031 obo:IAO_0000115 "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P." ; oboInOwl:created_by ; oboInOwl:creation_date "2018-01-25T23:20:13Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:label "enables subfunction" ; rdfs:subPropertyOf obo:RO_0002328 ; owl:propertyChainAxiom (obo:RO_0002327 obo:BFO_0000051 ) . obo:RO_0004032 obo:RO_0004049 obo:RO_0002264 ; oboInOwl:created_by ; oboInOwl:creation_date "2018-01-26T23:49:30Z"^^xsd:dateTime ; oboInOwl:inSubset obo:valid_for_go_gp2term ; a owl:ObjectProperty ; rdfs:label "acts upstream of or within, positive effect" ; rdfs:seeAlso "https://wiki.geneontology.org/Acts_upstream_of_or_within,_positive_effect"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002264 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0004047 ) . obo:RO_0004033 obo:RO_0004050 obo:RO_0002264 ; oboInOwl:created_by ; oboInOwl:creation_date "2018-01-26T23:49:51Z"^^xsd:dateTime ; oboInOwl:inSubset obo:valid_for_go_gp2term ; a owl:ObjectProperty ; rdfs:label "acts upstream of or within, negative effect" ; rdfs:seeAlso "https://wiki.geneontology.org/Acts_upstream_of_or_within,_negative_effect"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002264 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0004046 ) . obo:RO_0004034 obo:IAO_0000115 "c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive" ; obo:RO_0004049 obo:RO_0002263 ; oboInOwl:created_by ; oboInOwl:creation_date "2018-01-26T23:53:14Z"^^xsd:dateTime ; oboInOwl:inSubset obo:valid_for_go_gp2term ; a owl:ObjectProperty ; rdfs:label "acts upstream of, positive effect" ; rdfs:seeAlso "https://wiki.geneontology.org/Acts_upstream_of,_positive_effect"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002263, obo:RO_0004032 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002304 ) . obo:RO_0004035 obo:IAO_0000115 "c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative" ; obo:RO_0004050 obo:RO_0002263 ; oboInOwl:created_by ; oboInOwl:creation_date "2018-01-26T23:53:22Z"^^xsd:dateTime ; oboInOwl:inSubset obo:valid_for_go_gp2term ; a owl:ObjectProperty ; rdfs:label "acts upstream of, negative effect" ; rdfs:seeAlso "https://wiki.geneontology.org/Acts_upstream_of,_negative_effect"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002263, obo:RO_0004033 ; owl:propertyChainAxiom (obo:RO_0002327 obo:RO_0002305 ) . obo:RO_0004046 obo:RO_0004050 obo:RO_0002418 ; oboInOwl:created_by ; oboInOwl:creation_date "2018-03-13T23:55:05Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:label "causally upstream of or within, negative effect" ; rdfs:seeAlso "https://wiki.geneontology.org/Causally_upstream_of_or_within,_negative_effect"^^xsd:anyURI ; rdfs:subPropertyOf obo:RO_0002418 . obo:RO_0004047 obo:RO_0004049 obo:RO_0002418 ; oboInOwl:created_by ; oboInOwl:creation_date "2018-03-13T23:55:19Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:label "causally upstream of or within, positive effect" ; rdfs:seeAlso ; rdfs:subPropertyOf obo:RO_0002418 . obo:RO_0004049 a owl:AnnotationProperty . obo:RO_0004050 a owl:AnnotationProperty . obo:RO_0011002 obo:IAO_0000115 "The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B." ; obo:IAO_0000117 ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000040 ; rdfs:label "regulates activity of" ; rdfs:range obo:BFO_0000040 ; rdfs:subPropertyOf obo:RO_0002566 . obo:RO_0012011 obo:IAO_0000115 "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q." ; oboInOwl:created_by ; oboInOwl:creation_date "2022-09-26T06:07:17Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:label "indirectly causally upstream of"@en ; rdfs:subPropertyOf obo:RO_0002411 . obo:RO_0012012 obo:IAO_0000115 "p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q." ; oboInOwl:created_by ; oboInOwl:creation_date "2022-09-26T06:08:01Z"^^xsd:dateTime ; a owl:ObjectProperty ; rdfs:label "indirectly regulates"@en ; rdfs:subPropertyOf obo:RO_0002211, obo:RO_0012011 . obo:RO_0015007 a owl:ObjectProperty . obo:RO_0015008 a owl:ObjectProperty . obo:RO_0015011 a owl:ObjectProperty . obo:RO_0015012 a owl:ObjectProperty . obo:RO_0017001 obo:IAO_0000112 "A diagnostic testing device utilizes a specimen." ; obo:IAO_0000115 "X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y." ; obo:IAO_0000117 , ; obo:IAO_0000232 "A diagnostic testing device utilizes a specimen means that the diagnostic testing device is capable of an assay, and this assay a specimen as its input.", "See github ticket https://github.com/oborel/obo-relations/issues/497" ; oboInOwl:creation_date "2021-11-08T12:00:00Z"^^xsd:dateTime ; oboInOwl:hasBroadSynonym "utilizes" ; a owl:ObjectProperty ; rdfs:label "device utilizes material"@en ; owl:propertyChainAxiom (obo:RO_0002215 obo:RO_0002233 ) . obo:RO_0019000 obo:IAO_0000115 "A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C." ; terms:contributor ; a owl:ObjectProperty ; rdfs:domain obo:BFO_0000015 ; rdfs:label "regulates characteristic" ; rdfs:range obo:PATO_0000001 ; rdfs:subPropertyOf obo:RO_0002410 ; owl:propertyChainAxiom (obo:RO_0002211 obo:RO_0019000 ) . obo:RO_0019001 obo:IAO_0000115 "A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C." ; terms:contributor ; a owl:ObjectProperty ; rdfs:label "positively regulates characteristic" ; rdfs:subPropertyOf obo:RO_0019000 ; owl:propertyChainAxiom (obo:RO_0002213 obo:RO_0019001 ) . obo:RO_0019002 obo:IAO_0000115 "A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C." ; terms:contributor ; a owl:ObjectProperty ; rdfs:label "negatively regulates characteristic" ; rdfs:subPropertyOf obo:RO_0019000 ; owl:propertyChainAxiom (obo:RO_0002212 obo:RO_0019001 ), (obo:RO_0002213 obo:RO_0019002 ) . obo:RO_0040042 a owl:AnnotationProperty . obo:UBERON_0000061 obo:IAO_0000115 "Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome." ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "AAO:0010825", "AEO:0000003", "BILA:0000003", "CARO:0000003", "EHDAA2:0003003", "EMAPA:0", "FBbt:00007001", "FMA:305751", "FMA:67135", "GAID:781", "HAO:0000003", "MA:0003000", "MESH:D000825", "SCTID:362889002", "TAO:0000037", "TGMA:0001823", "VHOG:0001759", "XAO:0003000", "ZFA:0000037", "http://dbpedia.org/ontology/AnatomicalStructure" ; oboInOwl:hasExactSynonym "biological structure", "connected biological structure" ; oboInOwl:id "UBERON:0000061" ; oboInOwl:inSubset core:common_anatomy, core:upper_level ; a owl:Class ; rdfs:label "anatomical structure" ; rdfs:subClassOf obo:UBERON_0000465 . obo:UBERON_0000062 a owl:Class . obo:UBERON_0000115 a owl:Class . obo:UBERON_0000465 obo:IAO_0000115 "Anatomical entity that has mass." ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "AAO:0010264", "AEO:0000006", "BILA:0000006", "CARO:0000006", "EHDAA2:0003006", "FBbt:00007016", "FMA:67165", "HAO:0000006", "TAO:0001836", "TGMA:0001826", "VHOG:0001721" ; oboInOwl:id "UBERON:0000465" ; oboInOwl:inSubset core:common_anatomy, core:upper_level ; a owl:Class ; rdfs:label "material anatomical entity" ; rdfs:subClassOf obo:BFO_0000040, obo:UBERON_0001062 . obo:UBERON_0000483 a owl:Class . obo:UBERON_0000922 a owl:Class . obo:UBERON_0001004 a owl:Class . obo:UBERON_0001016 a owl:Class . obo:UBERON_0001062 obo:IAO_0000115 "Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species." ; obo:RO_0002175 obo:NCBITaxon_33090, obo:NCBITaxon_4751 ; oboInOwl:hasDbXref "AAO:0010841", "AEO:0000000", "BILA:0000000", "BIRNLEX:6", "CARO:0000000", "EHDAA2:0002229", "FBbt:10000000", "FMA:62955", "HAO:0000000", "MA:0000001", "NCIT:C12219", "TAO:0100000", "TGMA:0001822", "UMLS:C1515976", "WBbt:0000100", "XAO:0000000", "ZFA:0100000" ; oboInOwl:id "UBERON:0001062" ; oboInOwl:inSubset core:common_anatomy, core:upper_level ; a owl:Class ; rdfs:label "anatomical entity" ; rdfs:subClassOf obo:BFO_0000004 . obo:UBERON_0002048 a owl:Class . obo:UBERON_0002606 a owl:Class . obo:UBERON_0004802 a owl:Class . obo:WBPhenotype_0000000 obo:IAO_0000115 "Variations in the frequencies of translocations, inversions, deletions, or gene amplifications and variations in chromosome fusion events and or chromosomal loss compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000000" ; a owl:Class ; rdfs:label "chromosome instability" ; rdfs:subClassOf obo:WBPhenotype_0000585 . obo:WBPhenotype_0000001 obo:IAO_0000115 "Animals exhibit variations in body posture compared to control animals. For example, in C. elegans characteristic sinusoidal body posture is altered." ; oboInOwl:hasNarrowSynonym "body posture abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000001" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "body posture variant" ; rdfs:subClassOf obo:WBPhenotype_0000525 . obo:WBPhenotype_0000002 obo:IAO_0000115 "The animal moves or rests with uncharacteristic loss of smooth sinusoidal motion or body posture. Movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000002" ; a owl:Class ; rdfs:label "kinker" ; rdfs:subClassOf obo:WBPhenotype_0004017 . obo:WBPhenotype_0000003 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0001309 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000003" ; a owl:Class ; rdfs:label "obsolete flattened locomotion path" ; owl:deprecated true . obo:WBPhenotype_0000004 obo:IAO_0000115 "Eggs are laid under conditions where egg laying is normally inhibited." ; oboInOwl:hasBroadSynonym "Egl c" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000004" ; a owl:Class ; rdfs:comment "Liquid M9." ; rdfs:label "constitutive egg laying" ; rdfs:subClassOf obo:WBPhenotype_0000005 . obo:WBPhenotype_0000005 obo:IAO_0000115 "Eggs are laid at an earlier stage of development, eggs are laid in the presence of inhibitors of egg laying, or the inactive phase of the egg-laying cycle is significantly shorter when compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000005" ; a owl:Class ; rdfs:label "hyperactive egg laying" ; rdfs:subClassOf obo:WBPhenotype_0000640, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000006 obo:IAO_0000115 "Eggs are not laid, laid at a slower rate or eggs are laid at a later stage of development compared to control." ; oboInOwl:hasBroadSynonym "Egl d" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000006" ; a owl:Class ; rdfs:label "egg laying defective" ; rdfs:subClassOf obo:WBPhenotype_0000640, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001558 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001558 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] . obo:WBPhenotype_0000007 obo:IAO_0000115 "A worm carcass is formed with retained eggs that hatch inside." ; oboInOwl:hasBroadSynonym "Bag" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000007" ; a owl:Class ; rdfs:label "bag of worms" ; rdfs:subClassOf obo:WBPhenotype_0000862 . obo:WBPhenotype_0000008 obo:IAO_0000115 "Animals respond to anesthetic at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasExactSynonym "anaesthetic hypersensitive" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000008" ; a owl:Class ; rdfs:label "anesthetic hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0000627, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38867 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38867 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000009 obo:IAO_0000115 "Animals fail to respond to the concentration of anesthetic that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasExactSynonym "anaesthetic resistant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000009" ; a owl:Class ; rdfs:label "anesthetic resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0000627, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38867 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38867 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000010 obo:IAO_0000115 "Animals respond to a specific drug at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000010" ; a owl:Class ; rdfs:label "drug hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_23888 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_23888 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000011 obo:IAO_0000115 "Animals fail to respond to the concentration of a drug that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Animals are not affected by exposure to the drug." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000011" ; a owl:Class ; rdfs:label "drug resistant" ; rdfs:subClassOf obo:WBPhenotype_0000631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_23888 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_23888 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000012 obo:IAO_0000115 "Formation of dauer larvae under conditions that do not favor dauer formation." ; oboInOwl:hasBroadSynonym "Daf c" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000012" ; a owl:Class ; rdfs:label "dauer constitutive" ; rdfs:subClassOf obo:WBPhenotype_0000637 . obo:WBPhenotype_0000013 obo:IAO_0000115 "Failure to form dauer larvae under dauer-inducing conditions." ; oboInOwl:hasBroadSynonym "Daf d" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000013" ; a owl:Class ; rdfs:label "dauer defective" ; rdfs:subClassOf obo:WBPhenotype_0000637, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001558 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043053 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001558 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043053 ] ) ] ] . obo:WBPhenotype_0000014 obo:IAO_0000115 "Variations in the structure, organization or path of axon tracts that grow circumferentially around the animal in a single, directed trajectory to bridge the ventral and dorsal cords, compared to control animals." ; oboInOwl:hasNarrowSynonym "cord commissures abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000014" ; a owl:Class ; rdfs:label "cord commissures variant" ; rdfs:subClassOf obo:WBPhenotype_0001226 . obo:WBPhenotype_0000015 obo:IAO_0000115 "Variations in the movement towards typically attractive chemicals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000015" ; a owl:Class ; rdfs:label "positive chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0000635, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001558 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001558 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] ) ] ] . obo:WBPhenotype_0000016 obo:IAO_0000115 "Animals respond to aldicarb at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasBroadSynonym "Hic" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000016" ; a owl:Class ; rdfs:label "aldicarb hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000500, obo:WBPhenotype_0000680, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_2555 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_2555 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000017 obo:IAO_0000115 "Animals fail to respond to the concentration of aldicarb that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasBroadSynonym "Ald R", "Ric" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000017" ; a owl:Class ; rdfs:label "aldicarb resistant" ; rdfs:subClassOf obo:WBPhenotype_0000680, obo:WBPhenotype_0001289, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_2555 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_2555 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000018 obo:IAO_0000115 "The contraction and relaxation movements of the pharynx occur at a greater frequency compared to that observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000018" ; a owl:Class ; rdfs:label "pharyngeal pumping increased" ; rdfs:subClassOf obo:WBPhenotype_0001006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000019 obo:IAO_0000115 "Pharyngeal pumping motion occurs at a slower rate than control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000019" ; a owl:Class ; rdfs:label "pharyngeal pumping reduced" ; rdfs:subClassOf obo:WBPhenotype_0001006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000020 obo:IAO_0000115 "Pharyngeal pumping motion occurs at intervals that vary from control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000020" ; a owl:Class ; rdfs:label "pharyngeal pumping irregular" ; rdfs:subClassOf obo:WBPhenotype_0001006 . obo:WBPhenotype_0000021 obo:IAO_0000115 "Squat animals are dumpy as homozygotes, but roll as heterozygotes." ; oboInOwl:hasBroadSynonym "Sqt" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000021" ; a owl:Class ; rdfs:label "squat" ; rdfs:subClassOf obo:WBPhenotype_0000231 . obo:WBPhenotype_0000022 obo:IAO_0000115 "Animals are longer than control animals at the same developmental stage." ; oboInOwl:hasBroadSynonym "Lon" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000022" ; a owl:Class ; rdfs:label "long" ; rdfs:subClassOf obo:WBPhenotype_0000319, obo:WBPhenotype_0001726, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000573 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000573 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000023 obo:IAO_0000115 "Animals respond to serotonin at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000023" ; a owl:Class ; rdfs:label "serotonin hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000024 obo:IAO_0000115 "Animals fail to respond to the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000024" ; a owl:Class ; rdfs:label "serotonin resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000025 obo:IAO_0000115 "Fluid-filled blisters appear on the cuticle." ; oboInOwl:hasBroadSynonym "Bli" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000025" ; a owl:Class ; rdfs:label "blistered" ; rdfs:subClassOf obo:WBPhenotype_0000948, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001928 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001928 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000026 obo:IAO_0000115 "Animals are unable to take up or store lipids. In C. elegans, this defect results in pale, skinny and arrested larva." ; oboInOwl:hasBroadSynonym "Lpd" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "fat depleted" ; oboInOwl:id "WBPhenotype:0000026" ; a owl:Class ; rdfs:label "lipid depleted" ; rdfs:subClassOf obo:WBPhenotype_0001183 . obo:WBPhenotype_0000027 obo:IAO_0000115 "Variations in the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances compared to control." ; oboInOwl:hasNarrowSynonym "organism metabolism processing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000027" ; a owl:Class ; rdfs:label "organism metabolism processing variant" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0000028 obo:IAO_0000115 "Variations in the processes involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules compared to control." ; oboInOwl:hasNarrowSynonym "RNA processing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000028" ; a owl:Class ; rdfs:label "RNA processing variant" ; rdfs:subClassOf obo:WBPhenotype_0000113, obo:WBPhenotype_0001827, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006396 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006396 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000029 obo:IAO_0000115 "Animals are defective for RNAi introduced by environmental means such as in the cases of RNAi triggered by soaking or feeding." ; oboInOwl:hasNarrowSynonym "systemic RNAi abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Environmental RNAi defective" ; oboInOwl:id "WBPhenotype:0000029" ; a owl:Class ; rdfs:label "systemic RNAi variant" ; rdfs:subClassOf obo:WBPhenotype_0000743 . obo:WBPhenotype_0000030 obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) compared to control animals." ; oboInOwl:hasNarrowSynonym "growth abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000030" ; a owl:Class ; rdfs:label "growth variant" ; rdfs:subClassOf obo:WBPhenotype_0000577, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040007 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040007 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000031 obo:IAO_0000115 "Any variation that causes a reduction in growth rate compared to control." ; oboInOwl:hasBroadSynonym "Gro" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000031" ; a owl:Class ; rdfs:label "slow growth" ; rdfs:subClassOf obo:WBPhenotype_0000043, obo:WBPhenotype_0000438, obo:WBPhenotype_0000676, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040007 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040007 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000032 obo:IAO_0000115 "Animals exhibit some combination of abnormal features relating to size, movement, body integrity, pigmentation, viability, fertility etc." ; oboInOwl:hasBroadSynonym "Sck" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000032" ; a owl:Class ; rdfs:label "sick" ; rdfs:subClassOf obo:WBPhenotype_0000030 . obo:WBPhenotype_0000033 obo:IAO_0000115 "The timing of specific developmental events in some tissues is altered relative to the timing of events in other tissues." ; oboInOwl:hasAlternativeId "WBPhenotype:0000437" ; oboInOwl:hasExactSynonym "heterochronic defect" ; oboInOwl:hasNarrowSynonym "developmental timing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000033" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:comment "Possible XP GO:0040034." ; rdfs:label "developmental timing variant" ; rdfs:subClassOf obo:WBPhenotype_0000531, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040034 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040034 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000034 obo:IAO_0000115 "Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals." ; oboInOwl:hasNarrowSynonym "embryonic polarity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000034" ; a owl:Class ; rdfs:label "embryonic polarity variant" ; rdfs:subClassOf obo:WBPhenotype_0000749, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001769 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBls_0000003 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001769 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBls_0000003 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000035 obo:IAO_0000115 "Any variation in the overall structure or appearance of the animal as it progresses from hatching to adult compared to control animals." ; oboInOwl:hasNarrowSynonym "larval body morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "larval morphology abnormal" ; oboInOwl:id "WBPhenotype:0000035" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "larval body morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0000934, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] . obo:WBPhenotype_0000036 obo:IAO_0000115 "Any variation in the overall structure or appearance of the animal after it has completed progression through the larval stages compared to control animals." ; oboInOwl:hasNarrowSynonym "adult body morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000036" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "adult body morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0000934 . obo:WBPhenotype_0000037 obo:IAO_0000115 "Any variation in the overall structure or appearance of fertilized oocytes that are laid compared to those laid by control animals." ; oboInOwl:hasNarrowSynonym "egg morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000037" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "egg morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000934 . obo:WBPhenotype_0000038 obo:IAO_0000115 "The animal is ruptured at the vulva and displays an extrusion of internal organs at the site of rupture." ; oboInOwl:hasBroadSynonym "Rup" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "burst vulva", "gonad eversion", "gonad exploded through vulva", "rupture through vulva" ; oboInOwl:id "WBPhenotype:0000038" ; a owl:Class ; rdfs:label "exploded through vulva" ; rdfs:subClassOf obo:WBPhenotype_0000619 . obo:WBPhenotype_0000039 obo:IAO_0000115 "Adult life span is either longer or shorter than typical of control animals." ; oboInOwl:hasBroadSynonym "Age" ; oboInOwl:hasExactSynonym "life span abnormal", "life span variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "longevity abnormal" ; oboInOwl:id "WBPhenotype:0000039" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "life span phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000576, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000050 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000050 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000040 obo:IAO_0000115 "Embryos fail to divide and arrest as one-cell embryos." ; oboInOwl:hasBroadSynonym "Emb", "Ocs" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "catastrophic one cell arrest" ; oboInOwl:id "WBPhenotype:0000040" ; a owl:Class ; rdfs:label "one cell arrest early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100 . obo:WBPhenotype_0000041 obo:IAO_0000115 "Any variation in the process involved in the maintenance of an internal equilibrium of water within an organism, compared to control." ; oboInOwl:hasNarrowSynonym "osmotic integrity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "osmoregulation variant" ; oboInOwl:id "WBPhenotype:0000041" ; a owl:Class ; rdfs:label "osmotic integrity variant" ; rdfs:subClassOf obo:WBPhenotype_0000577, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030104 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030104 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000042 obo:IAO_0000115 "The progression through stages between fertilization to hatching are temporally retarded." ; oboInOwl:hasBroadSynonym "Sle" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000042" ; a owl:Class ; rdfs:label "slow embryonic development" ; rdfs:subClassOf obo:WBPhenotype_0000674, obo:WBPhenotype_0000749, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000043 obo:IAO_0000115 "Variations in the progression time of an animal from pronuclei meeting to adulthood compared to control animals." ; oboInOwl:hasNarrowSynonym "general pace of development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000043" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "general pace of development variant" ; rdfs:subClassOf obo:WBPhenotype_0000033, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000161 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032502 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000161 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032502 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000044 obo:IAO_0000115 "Egg is smaller or larger compared to eggs of control animals." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000044" ; a owl:Class ; rdfs:label "egg size defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002407 . obo:WBPhenotype_0000045 obo:IAO_0000115 "The developmental progression of an animal after the embryonic stage, over time, from its formation to its mature structure is delayed compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000045" ; a owl:Class ; rdfs:label "developmental delay postembryonic" ; rdfs:subClassOf obo:WBPhenotype_0000049, obo:WBPhenotype_0000848 . obo:WBPhenotype_0000046 obo:IAO_0000115 "More than five minutes between AB and P1 divisions." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pace of P lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000046" ; a owl:Class ; rdfs:label "pace of P lineage defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000746, obo:WBPhenotype_0000824 . obo:WBPhenotype_0000047 obo:IAO_0000115 "Variations in the process by which the germ layers become positioned in an embryo compared to control animals. Gastrulation involves the proper ingression of small groups of cells at various times into the blastocoel space." ; oboInOwl:hasNarrowSynonym "gastrulation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000047" ; a owl:Class ; rdfs:label "gastrulation variant" ; rdfs:subClassOf obo:WBPhenotype_0000749, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007369 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007369 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000048 obo:IAO_0000115 "Variations in the ability of an animal to emerge from the protective egg shell compared to control animals." ; oboInOwl:hasNarrowSynonym "hatching abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000048" ; a owl:Class ; rdfs:label "hatching variant" ; rdfs:subClassOf obo:WBPhenotype_0000749, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035188 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035188 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000049 obo:IAO_0000115 "Any variation in the progression of an animal over time, from hatching to adulthood, compared to control." ; oboInOwl:hasNarrowSynonym "postembryonic development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000049" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "postembryonic development variant" ; rdfs:subClassOf obo:WBPhenotype_0000531, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009791 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009791 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000050 obo:IAO_0000115 "Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "egg lethal", "embryonic death", "inviable zygote" ; oboInOwl:id "WBPhenotype:0000050" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "embryonic lethal" ; rdfs:subClassOf obo:WBPhenotype_0000062, obo:WBPhenotype_0000749, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000003 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000003 ] ) ] ] . obo:WBPhenotype_0000051 obo:IAO_0000115 "The developmental program does not continue past embryogenesis; stage of arrest is not consistent from animal to animal." ; oboInOwl:hasBroadSynonym "Emb", "Etv" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000051" ; a owl:Class ; rdfs:label "embryonic terminal arrest variable emb" ; rdfs:subClassOf obo:WBPhenotype_0000063, obo:WBPhenotype_0000749 . obo:WBPhenotype_0000052 obo:IAO_0000115 "Lethality caused by the perturbation of maternal gene products that are contributed to oogenesis and are required during embryogenesis." ; oboInOwl:hasBroadSynonym "Emb", "Mel" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000052" ; a owl:Class ; rdfs:label "maternal effect lethal emb" ; rdfs:subClassOf obo:WBPhenotype_0000050 . obo:WBPhenotype_0000053 obo:IAO_0000115 "Movement and elongation ceases at the two-fold stage. The myofilament lattice in body wall muscle cells is variant. However, development in embryos continues. Embryos hatch as inviable larvae." ; oboInOwl:hasBroadSynonym "Pat" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "active elongation arrest", "two fold arrest" ; oboInOwl:id "WBPhenotype:0000053" ; a owl:Class ; rdfs:label "paralyzed arrested elongation two fold" ; rdfs:subClassOf obo:WBPhenotype_0000050, obo:WBPhenotype_0000494 . obo:WBPhenotype_0000054 obo:IAO_0000115 "The animal dies at any time between hatching and onset to adulthood." ; oboInOwl:hasBroadSynonym "Let", "Lvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "larval death" ; oboInOwl:id "WBPhenotype:0000054" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "larval lethal" ; rdfs:subClassOf obo:WBPhenotype_0000062, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] . obo:WBPhenotype_0000055 obo:IAO_0000115 "Larvae arrest during early larval development. In C. elegans, this occurs during the L1 or L2 stages of larval development." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000055" ; a owl:Class ; rdfs:label "early larval arrest" ; rdfs:subClassOf obo:WBPhenotype_0000059, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000024 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000024 ] ) ] ] . obo:WBPhenotype_0000056 obo:IAO_0000115 "Larvae arrest during late larval development. In C. elegans, larval arrest occurs during the L3 or L4 stages of larval development." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000056" ; a owl:Class ; rdfs:label "late larval arrest" ; rdfs:subClassOf obo:WBPhenotype_0000059 . obo:WBPhenotype_0000057 obo:IAO_0000115 "Animals die during early larval development. In C.elegans, this occurs during the L1- L2 larval stages of the life cycle." ; oboInOwl:hasBroadSynonym "Let", "Lvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000057" ; a owl:Class ; rdfs:label "early larval lethal" ; rdfs:subClassOf obo:WBPhenotype_0000054, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000024 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000024 ] ) ] ] . obo:WBPhenotype_0000058 obo:IAO_0000115 "Animals die during late larval development. In C. elegans, this occurs during the L3- L4 larval stages of the life cycle." ; oboInOwl:hasBroadSynonym "Let", "Lvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000058" ; a owl:Class ; rdfs:label "late larval lethal" ; rdfs:subClassOf obo:WBPhenotype_0000054 . obo:WBPhenotype_0000059 obo:IAO_0000115 "The developmental program of the animals halts at any larval stage and thus fails to reach adulthood. In C.elegans, this occurs anytime during L1-L4 stage." ; oboInOwl:hasBroadSynonym "Lva" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000059" ; a owl:Class ; rdfs:label "larval arrest" ; rdfs:subClassOf obo:WBPhenotype_0000750, obo:WBPhenotype_0001016, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] ) ] ] . obo:WBPhenotype_0000060 obo:IAO_0000115 "Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background." ; oboInOwl:hasBroadSynonym "Adl", "Let" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000060" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "adult lethal" ; rdfs:subClassOf obo:WBPhenotype_0000062, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000041 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000041 ] ) ] ] . obo:WBPhenotype_0000061 obo:IAO_0000115 "The duration of viability in the adult phase of the life-cycle surpasses that of control animals." ; oboInOwl:hasBroadSynonym "Age" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "life span increased", "longevity increased" ; oboInOwl:id "WBPhenotype:0000061" ; a owl:Class ; rdfs:label "extended life span" ; rdfs:subClassOf obo:WBPhenotype_0000039, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001603 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001603 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] . obo:WBPhenotype_0000062 obo:IAO_0000115 "Animals die prematurely at any stage of the life cycle." ; oboInOwl:hasBroadSynonym "Let" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000062" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "lethal" ; rdfs:subClassOf obo:WBPhenotype_0000531, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] . obo:WBPhenotype_0000063 obo:IAO_0000115 "Variations that cause developmental progression to cease at different stages of the lifecycle." ; oboInOwl:hasBroadSynonym "Var" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000063" ; a owl:Class ; rdfs:label "terminal arrest variable" ; rdfs:subClassOf obo:WBPhenotype_0000062 . obo:WBPhenotype_0000064 obo:IAO_0000115 "Animals die prematurely at any stage of the life cycle in a sex dependent manner." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Let" ; oboInOwl:id "WBPhenotype:0000064" ; a owl:Class ; rdfs:label "sexually dimorphic lethality" ; rdfs:subClassOf obo:WBPhenotype_0000062 . obo:WBPhenotype_0000065 obo:IAO_0000115 "XO-bearing individuals die preferentially over other animals in the population. In C.elegans, X0 animals die preferentially over XX animals." ; oboInOwl:hasBroadSynonym "Let" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "male specific lethality" ; oboInOwl:id "WBPhenotype:0000065" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "X0 lethal" ; rdfs:subClassOf obo:WBPhenotype_0000064 . obo:WBPhenotype_0000066 obo:IAO_0000115 "XX-bearing individuals die preferentially over other animals in the population. In C.elegans, XX animals die preferentially over X0 animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "hermaphrodite specific lethality" ; oboInOwl:id "WBPhenotype:0000066" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "XX lethal" ; rdfs:subClassOf obo:WBPhenotype_0000064 . obo:WBPhenotype_0000067 obo:IAO_0000115 "Animals exhibit variations in response to stress stimuli compared to control animals." ; oboInOwl:hasNarrowSynonym "organism stress response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000067" ; a owl:Class ; rdfs:label "organism stress response variant" ; rdfs:subClassOf obo:WBPhenotype_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006950 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006950 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000068 obo:IAO_0000115 "Any variation in the state or activity of a cell (in terms of secretion, enzyme production, gene expression, etc.) in response to high levels of reactive oxygen species, compared to control." ; oboInOwl:hasNarrowSynonym "oxidative stress response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000068" ; a owl:Class ; rdfs:label "cellular oxidative stress response variant" ; rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0000523, obo:WBPhenotype_0001620, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034599 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034599 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000069 obo:IAO_0000115 "Any variation in the progression of the progeny of an animal at any time from its fertilization to adulthood compared to control." ; oboInOwl:hasNarrowSynonym "progeny abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000069" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "progeny variant" ; rdfs:subClassOf obo:WBPhenotype_0000531 . obo:WBPhenotype_0000070 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the somatic reproductive components of the posterior segment of the male from that observed in control males. In C. elegans, this region of the male includes the terminal canals of the reproductive tract, the digestive tract, and spicule channels along with the male specific sensilla (ray, post-cloacal, hook and spicule) and extends to the tip of the acellular fan." ; oboInOwl:hasBroadSynonym "Mab" ; oboInOwl:hasNarrowSynonym "male tail morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000070" ; a owl:Class ; rdfs:label "male tail morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000073, obo:WBPhenotype_0001024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000071 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any portion of their anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring) compared to control." ; oboInOwl:hasNarrowSynonym "head morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000071" ; a owl:Class ; rdfs:label "head morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000532, obo:WBPhenotype_0000582, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000072 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any portion of their anatomy between the head and the tail compared to control animals." ; oboInOwl:hasNarrowSynonym "body morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000072" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "body morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000532, obo:WBPhenotype_0000582, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005740 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005740 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000073 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any portion of the most posterior region of the body compared to control. The anterior bound of the tail is not well defined though it might range from the position of the post-deirids to the opening of the anus (Wormatlas)." ; oboInOwl:hasNarrowSynonym "tail morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000073" ; a owl:Class ; rdfs:label "tail morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000532, obo:WBPhenotype_0000582, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000074 obo:IAO_0000115 "Any variation in the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control." ; oboInOwl:hasNarrowSynonym "genetic pathway abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000074" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "genetic pathway variant" ; rdfs:subClassOf obo:WBPhenotype_0000576 . obo:WBPhenotype_0000075 obo:IAO_0000115 "Any variation in the attachment of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) to the outer body of an animal compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "cuticle attachment abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000075" ; a owl:Class ; rdfs:label "cuticle attachment variant" ; rdfs:subClassOf obo:WBPhenotype_0000201, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000076 obo:IAO_0000115 "Variations in the adhesion of the layer of cells that cover the external surface of an organism which serves to protect the animal from external environment compared to control." ; oboInOwl:hasNarrowSynonym "epithelial attachment abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "hypodermal attachment abnormal" ; oboInOwl:id "WBPhenotype:0000076" ; a owl:Class ; rdfs:label "epithelial attachment variant" ; rdfs:subClassOf obo:WBPhenotype_0000608 . obo:WBPhenotype_0000077 obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement." ; oboInOwl:hasNarrowSynonym "cuticle shedding abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000077" ; a owl:Class ; rdfs:label "cuticle shedding defect" ; rdfs:subClassOf obo:WBPhenotype_0000638 . obo:WBPhenotype_0000078 obo:IAO_0000115 "The hypodermal cells, which lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, are misplaced such that they are stacked along the dorsal-ventral axis rather than forming a continuous row of adjacent cells ." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000078" ; a owl:Class ; rdfs:label "seam cells stacked" ; rdfs:subClassOf obo:WBPhenotype_0000703 . obo:WBPhenotype_0000079 obo:IAO_0000115 "The small linear ridges running along the lateral lines of the cuticle of adults are branched as opposed to having an unbiforcated arrangement, lengthwise along the body (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000079" ; a owl:Class ; rdfs:label "branched adult alae" ; rdfs:subClassOf obo:WBPhenotype_0001412, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000402 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007832 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000402 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007832 ] ) ] ] . obo:WBPhenotype_0000080 obo:IAO_0000115 "Animals lack the anterior portion of the pharynx." ; oboInOwl:hasBroadSynonym "Aph" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000080" ; a owl:Class ; rdfs:label "no anterior pharynx" ; rdfs:subClassOf obo:WBPhenotype_0000115, obo:WBPhenotype_0001646, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003733 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003733 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000081 obo:IAO_0000115 "The developmental program of the animals does not continue past the first larval stage (L1)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000081" ; a owl:Class ; rdfs:label "L1 arrest" ; rdfs:subClassOf obo:WBPhenotype_0000055, obo:WBPhenotype_0000751, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000024 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000024 ] ) ] ] . obo:WBPhenotype_0000082 obo:IAO_0000115 "The developmental program of the animals does not continue past the second larval stage (L2)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000082" ; a owl:Class ; rdfs:label "L2 arrest" ; rdfs:subClassOf obo:WBPhenotype_0000055, obo:WBPhenotype_0000752, obo:WBPhenotype_0001019, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] ) ] ] . obo:WBPhenotype_0000083 obo:IAO_0000115 "The developmental program of the animals does not continue past the third larval stage (L3)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000083" ; a owl:Class ; rdfs:label "L3 arrest" ; rdfs:subClassOf obo:WBPhenotype_0000056, obo:WBPhenotype_0000753, obo:WBPhenotype_0001019, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000035 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000035 ] ) ] ] . obo:WBPhenotype_0000084 obo:IAO_0000115 "The developmental program of the animals does not continue past the fourth larval stage (L4)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000084" ; a owl:Class ; rdfs:label "L4 arrest" ; rdfs:subClassOf obo:WBPhenotype_0000056, obo:WBPhenotype_0000754, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000038 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000038 ] ) ] ] . obo:WBPhenotype_0000085 obo:IAO_0000115 "The intestinal lumen is expanded and can often be shown to be filled with bacteria. This swelling is distinct from distension of the entire intestine (intestinal edema)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000085" ; a owl:Class ; rdfs:label "swollen intestinal lumen" ; rdfs:subClassOf obo:WBPhenotype_0000710, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001851 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001851 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] ) ] ] . obo:WBPhenotype_0000086 obo:IAO_0000115 "Intestine is shrunken and may appear constricted." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000086" ; a owl:Class ; rdfs:label "shrunken intestine" ; rdfs:subClassOf obo:WBPhenotype_0000710, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000585 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000585 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] ) ] ] . obo:WBPhenotype_0000087 obo:IAO_0000115 "Any variation in the progression of a body wall muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "body wall cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "body wall muscle cell development abnormal" ; oboInOwl:id "WBPhenotype:0000087" ; a owl:Class ; rdfs:label "body wall cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000815, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006804 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006804 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000088 obo:IAO_0000115 "The arrangement of the principal muscle cell type whose contractile activity generates body motion in the nematode differs from that observed in control animals. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "body wall muscle displaced" ; oboInOwl:id "WBPhenotype:0000088" ; a owl:Class ; rdfs:label "body muscle displaced" ; rdfs:subClassOf obo:WBPhenotype_0000861 . obo:WBPhenotype_0000089 obo:IAO_0000115 "Animals fail to respond to the concentration of alpha amanitin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000089" ; a owl:Class ; rdfs:label "alpha amanitin resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_37415 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_37415 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000090 obo:IAO_0000115 "Animals are deficient in the adhesion of the cuticle to the epidermal surface of the animal." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "hypodermis detached from cuticle" ; oboInOwl:id "WBPhenotype:0000090" ; a owl:Class ; rdfs:label "epidermis cuticle detached" ; rdfs:subClassOf obo:WBPhenotype_0000075, obo:WBPhenotype_0000076, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005733 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005733 ] ) ] ] . obo:WBPhenotype_0000091 obo:IAO_0000115 "The cell(s) whose principal function is to provide contractile forces, is separated from the adjacent epidermis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "hypodermis detached from muscle" ; oboInOwl:id "WBPhenotype:0000091" ; a owl:Class ; rdfs:label "epidermis muscle detached" ; rdfs:subClassOf obo:WBPhenotype_0000076, obo:WBPhenotype_0000475, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005733 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005733 ] ) ] ] . obo:WBPhenotype_0000092 obo:IAO_0000115 "Any variation in the processes that govern the expansion of intestinal cell populations compared to control." ; oboInOwl:hasNarrowSynonym "intestinal cell proliferation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000092" ; a owl:Class ; rdfs:label "intestinal cell proliferation variant" ; rdfs:subClassOf obo:WBPhenotype_0000171, obo:WBPhenotype_0000536, obo:WBPhenotype_0000705, obo:WBPhenotype_0001093, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005792 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008283 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005792 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000093 obo:IAO_0000115 "The descendants of a particular precursor cell exhibit variations in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasBroadSynonym "Lin" ; oboInOwl:hasNarrowSynonym "lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000093" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000529 . obo:WBPhenotype_0000094 obo:IAO_0000115 "Any variation in the progression of the caudal opening of the rectum in the tail over time compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "anus development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000094" ; a owl:Class ; rdfs:label "anus development variant" ; rdfs:subClassOf obo:WBPhenotype_0000617, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005364 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005364 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000095 obo:IAO_0000115 "The descendants of the M precursor cell exhibit variations in developmental programs compared to their counterparts in control animals. In C. elegans the M lineage is a postembryonic mesodermal lineage." ; oboInOwl:hasNarrowSynonym "M lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000095" ; a owl:Class ; rdfs:label "M lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000825, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008439 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008439 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000096 obo:IAO_0000115 "Variations in the progression of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) over time compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "cloacal development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000096" ; a owl:Class ; rdfs:label "cloacal development variant" ; rdfs:subClassOf obo:WBPhenotype_0000617, obo:WBPhenotype_0000930, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005774 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005774 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000097 obo:IAO_0000115 "The descendants of the AB blastomere exhibit variations in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "AB lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000097" ; a owl:Class ; rdfs:label "AB lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000824, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008611 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008611 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000098 obo:IAO_0000115 "Any variation in the progression of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine over time compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas)." ; oboInOwl:hasNarrowSynonym "pharyngeal intestinal valve development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000098" ; a owl:Class ; rdfs:label "pharyngeal intestinal valve development variant" ; rdfs:subClassOf obo:WBPhenotype_0000617, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005767 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005767 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000099 obo:IAO_0000115 "The descendants of any of the P precursor cells exhibit variations in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "P lineages abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000099" ; a owl:Class ; rdfs:label "P lineages variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000825, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008590 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008590 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000100 obo:IAO_0000115 "Cells exhibit variations in their response to ultraviolet radiation compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "cell UV response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000100" ; a owl:Class ; rdfs:label "cell UV response variant" ; rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0000143, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034644 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034644 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000101 obo:IAO_0000115 "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, UV irradiation, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000101" ; a owl:Class ; rdfs:label "UV induced apoptosis increased" ; rdfs:subClassOf obo:WBPhenotype_0000100, obo:WBPhenotype_0000183 . obo:WBPhenotype_0000102 obo:IAO_0000115 "Animals display variations in the organization, accumulation or distribution of transmitter-containing membrane-bound organelles (synaptic vesicles) compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "presynaptic vesicle cluster abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "synaptic vesicle cluster abnormal" ; oboInOwl:id "WBPhenotype:0000102" ; a owl:Class ; rdfs:label "presynaptic vesicle cluster variant" ; rdfs:subClassOf obo:WBPhenotype_0000846, obo:WBPhenotype_0001321, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0097091 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0097091 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000103 obo:IAO_0000115 "Any variation in the progression of the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes over time compared to control. In C. elegans these contents might include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ; oboInOwl:hasNarrowSynonym "gut granule development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000103" ; a owl:Class ; rdfs:label "gut granule development variant" ; rdfs:subClassOf obo:WBPhenotype_0000705, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:GO_0044840 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:GO_0044840 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000104 obo:IAO_0000115 "Contents or structures of a cell are no longer restricted/localized to their typical positions within the cell." ; oboInOwl:hasNarrowSynonym "cell polarity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000104" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell polarity variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007163 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007163 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000105 obo:IAO_0000115 "Variations in the progression of a developing oocyte, from diakinesis to metaphase (meiosis I), in response to a signal compared to control animals. Meiotic maturation is accompanied by nuclear envelope breakdown (germinal vesicle breakdown), cytoskeletal rearrangement and meiotic spindle assembly." ; oboInOwl:hasBroadSynonym "Oma" ; oboInOwl:hasNarrowSynonym "oocyte meiotic maturation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000105" ; a owl:Class ; rdfs:label "oocyte meiotic maturation variant" ; rdfs:subClassOf obo:WBPhenotype_0000313, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1903537 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1903537 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000106 obo:IAO_0000115 "Variations in the processes that negatively regulate the meiotic progression of oocytes (exit from diakinesis) in the absence of a signal compared to control animals." ; oboInOwl:hasNarrowSynonym "inhibition of oocyte maturation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000106" ; a owl:Class ; rdfs:label "inhibition of oocyte maturation variant" ; rdfs:subClassOf obo:WBPhenotype_0000105, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1904145 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1904145 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000107 obo:IAO_0000115 "Any variation that alters the control mechanisms that inhibit oocyte maturation and release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control." ; oboInOwl:hasNarrowSynonym "inhibition of ovulation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000107" ; a owl:Class ; rdfs:label "inhibition of ovulation variant" ; rdfs:subClassOf obo:WBPhenotype_0000666, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060280 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060280 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000108 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0000583 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000108" ; a owl:Class ; rdfs:label "obsolete severe dumpy" ; owl:deprecated true . obo:WBPhenotype_0000109 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0000583 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000109" ; a owl:Class ; rdfs:label "obsolete moderate dumpy" ; owl:deprecated true . obo:WBPhenotype_0000110 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0000583 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000110" ; a owl:Class ; rdfs:label "obsolete slightly dumpy" ; owl:deprecated true . obo:WBPhenotype_0000111 obo:IAO_0000115 "Any variation in the cellular or subcellular distribution of a gene product compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "pattern of gene expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000111" ; a owl:Class ; rdfs:label "pattern of gene expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000717 . obo:WBPhenotype_0000112 obo:IAO_0000115 "Variations in the biogenesis and stability of protein molecules compared to control." ; oboInOwl:hasNarrowSynonym "protein expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000112" ; a owl:Class ; rdfs:label "protein expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000717 . obo:WBPhenotype_0000113 obo:IAO_0000115 "Variations in the biogenesis and stability of any class of RNA molecules (rRNAs, miRNAs, tRNAs etc) compared to control." ; oboInOwl:hasNarrowSynonym "RNA expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000113" ; a owl:Class ; rdfs:label "RNA expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000717 . obo:WBPhenotype_0000114 obo:IAO_0000115 "Variations in the biogenesis and stability of messenger RNA molecules compared to control." ; oboInOwl:hasNarrowSynonym "mRNA expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000114" ; a owl:Class ; rdfs:label "mRNA expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000113 . obo:WBPhenotype_0000115 obo:IAO_0000115 "Any variation in the progression of the anterior portion of the pharynx over time compared to control. In C. elegans the anterior region includes the corpus (procorpus and metacorpus - first bulb)." ; oboInOwl:hasNarrowSynonym "anterior pharynx abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000115" ; a owl:Class ; rdfs:label "anterior pharynx variant" ; rdfs:subClassOf obo:WBPhenotype_0000707 . obo:WBPhenotype_0000116 obo:IAO_0000115 "Animals die in between the early and late larval stages. In C. elegans, this occurs during the L2- L3 larval stages of the life cycle." ; oboInOwl:hasBroadSynonym "Let", "Lvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000116" ; a owl:Class ; rdfs:label "mid larval lethal" ; rdfs:subClassOf obo:WBPhenotype_0000054 . obo:WBPhenotype_0000117 obo:IAO_0000115 "Animals die at the L1 stage of the life cycle." ; oboInOwl:hasBroadSynonym "Let", "Lvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000117" ; a owl:Class ; rdfs:label "L1 lethal" ; rdfs:subClassOf obo:WBPhenotype_0000057, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000024 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000024 ] ) ] ] . obo:WBPhenotype_0000118 obo:IAO_0000115 "L2 lethal: Animals die at the L2 stage of the life cycle." ; oboInOwl:hasBroadSynonym "Let", "Lvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000118" ; a owl:Class ; rdfs:label "L2 lethal" ; rdfs:subClassOf obo:WBPhenotype_0000057, obo:WBPhenotype_0000116, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] ) ] ] . obo:WBPhenotype_0000119 obo:IAO_0000115 "Any change that results in higher than normal levels of protein expression compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000119" ; a owl:Class ; rdfs:label "protein expression increased" ; rdfs:subClassOf obo:WBPhenotype_0001400 . obo:WBPhenotype_0000120 obo:IAO_0000115 "Any change that results in lower than normal levels of protein expression compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000120" ; a owl:Class ; rdfs:label "protein expression reduced" ; rdfs:subClassOf obo:WBPhenotype_0001400 . obo:WBPhenotype_0000121 obo:IAO_0000115 "Variations in the chemical reactions and pathways resulting in the formation of a protein, compared to control." ; oboInOwl:hasNarrowSynonym "translation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "protein synthesis abnormal" ; oboInOwl:id "WBPhenotype:0000121" ; a owl:Class ; rdfs:label "translation variant" ; rdfs:subClassOf obo:WBPhenotype_0000112, obo:WBPhenotype_0001644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006412 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006412 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000122 obo:IAO_0000115 "Any variation in the posttranslational modification of a protein (which may include cleavage of peptide bonds) leading to the attainment of the full functional capacity of the protein compared to control." ; oboInOwl:hasNarrowSynonym "post translational processing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "protein processing variant" ; oboInOwl:id "WBPhenotype:0000122" ; a owl:Class ; rdfs:label "post translational processing variant" ; rdfs:subClassOf obo:WBPhenotype_0000027 . obo:WBPhenotype_0000123 obo:IAO_0000115 "Variations that cause a decrease in the expression level of a biological catalyst, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000123" ; a owl:Class ; rdfs:label "enzyme expression level reduced" ; rdfs:subClassOf obo:WBPhenotype_0000120 . obo:WBPhenotype_0000124 obo:IAO_0000115 "Any variation that results in a decrease in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000124" ; a owl:Class ; rdfs:label "enzyme activity reduced" ; rdfs:subClassOf obo:WBPhenotype_0000727, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0003824 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0003824 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000125 obo:IAO_0000115 "Any variation that results in an increase in the catalytic activity of an enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000125" ; a owl:Class ; rdfs:label "enzyme activity increased" ; rdfs:subClassOf obo:WBPhenotype_0000727, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0003824 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0003824 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000126 obo:IAO_0000115 "Variations in the time from pronuclei meeting to furrow initiation during the first cell division compared to control animals." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "general pace of development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000126" ; a owl:Class ; rdfs:label "general pace of development defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000043 . obo:WBPhenotype_0000127 obo:IAO_0000115 "Characteristic exit from the dauer stage is altered compared to control animals." ; oboInOwl:hasNarrowSynonym "dauer recovery abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000127" ; a owl:Class ; rdfs:label "dauer recovery variant" ; rdfs:subClassOf obo:WBPhenotype_0000308, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043054 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043054 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000128 obo:IAO_0000115 "Animals are more likely to form dauers at temperatures that do not induce dauer entry in control animals." ; oboInOwl:hasBroadSynonym "Hid" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000128" ; a owl:Class ; rdfs:label "temperature induced dauer formation increased" ; rdfs:subClassOf obo:WBPhenotype_0000639 . obo:WBPhenotype_0000129 obo:IAO_0000115 "Animals do not enter dauer at a temperature that induces dauer formation in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000129" ; a owl:Class ; rdfs:label "temperature induced dauer formation defective" ; rdfs:subClassOf obo:WBPhenotype_0000013, obo:WBPhenotype_0000639 . obo:WBPhenotype_0000130 obo:IAO_0000115 "Animals enter the dauer stage when exposed to lower concentrations or shorter exposure times of chemicals that induce dauer formation compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000130" ; a owl:Class ; rdfs:label "pheromone induced dauer formation enhanced" ; rdfs:subClassOf obo:WBPhenotype_0000132 . obo:WBPhenotype_0000131 obo:IAO_0000115 "Animals do not enter dauer when exposed to chemicals that induce dauer formation in control animals." ; oboInOwl:hasBroadSynonym "Phd" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000131" ; a owl:Class ; rdfs:label "pheromone induced dauer formation defective" ; rdfs:subClassOf obo:WBPhenotype_0000013, obo:WBPhenotype_0000132 . obo:WBPhenotype_0000132 obo:IAO_0000115 "Animals exhibit variations in the entry into the dauer stage when exposed to concentrations of chemicals that induce dauer formation in control animals." ; oboInOwl:hasNarrowSynonym "pheromone induced dauer formation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000132" ; a owl:Class ; rdfs:label "pheromone induced dauer formation variant" ; rdfs:subClassOf obo:WBPhenotype_0001539 . obo:WBPhenotype_0000133 obo:IAO_0000115 "The levels of an enzyme involved in the manufacture of lipids are decreased compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000133" ; a owl:Class ; rdfs:label "expression lipogenic enzyme reduced" ; rdfs:subClassOf obo:WBPhenotype_0000123 . obo:WBPhenotype_0000134 obo:IAO_0000115 "Animals exhibit a decrease in the intensity of expression of a gene product compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000134" ; a owl:Class ; rdfs:label "gene expression level reduced" ; rdfs:subClassOf obo:WBPhenotype_0002575 . obo:WBPhenotype_0000135 obo:IAO_0000115 "Animals exhibit an increase in the intensity of expression of a gene product compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000135" ; a owl:Class ; rdfs:label "gene expression level high" ; rdfs:subClassOf obo:WBPhenotype_0002575 . obo:WBPhenotype_0000136 obo:IAO_0000115 "Animals exhibit elevated levels of messenger RNA compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000136" ; a owl:Class ; rdfs:label "mRNA levels increased" ; rdfs:subClassOf obo:WBPhenotype_0000114, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_33699 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_33699 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000137 obo:IAO_0000115 "Animals exhibit decreased levels of messenger RNA compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000137" ; a owl:Class ; rdfs:label "mRNA levels reduced" ; rdfs:subClassOf obo:WBPhenotype_0000114, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_33699 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_33699 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000138 obo:IAO_0000115 "The constituent parts or ratio of elements that make up lipids are altered when compared to that of control animals." ; oboInOwl:hasNarrowSynonym "lipid composition abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "fat composition abnormal", "fatty acid composition abnormal" ; oboInOwl:id "WBPhenotype:0000138" ; a owl:Class ; rdfs:label "lipid composition variant" ; rdfs:subClassOf obo:WBPhenotype_0000725 . obo:WBPhenotype_0000139 obo:IAO_0000115 "Animals exhibit variations in survival when exposed to stress stimuli that induce lethality in control animals." ; oboInOwl:hasNarrowSynonym "stress induced lethality abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000139" ; a owl:Class ; rdfs:label "stress induced lethality variant" ; rdfs:subClassOf obo:WBPhenotype_0000067 . obo:WBPhenotype_0000140 obo:IAO_0000115 "Animals exhibit variations in cessation of development when exposed to stress stimuli that induce developmental arrest in control animals." ; oboInOwl:hasNarrowSynonym "stress induced arrest abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000140" ; a owl:Class ; rdfs:label "stress induced arrest variant" ; rdfs:subClassOf obo:WBPhenotype_0000067 . obo:WBPhenotype_0000141 obo:IAO_0000115 "Animal populations exhibit a further decrease in survival when exposed to stress stimuli compared to the lethality rate observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000141" ; a owl:Class ; rdfs:label "stress induced lethality increased" ; rdfs:subClassOf obo:WBPhenotype_0000139 . obo:WBPhenotype_0000142 obo:IAO_0000115 "Variations in the activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress, compared to control. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation)." ; oboInOwl:hasNarrowSynonym "cell stress response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000142" ; a owl:Class ; rdfs:label "cell stress response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, obo:WBPhenotype_0000585, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0033554 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000143 obo:IAO_0000115 "Animals exhibit variations in their response to ultraviolet radiation compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "organism UV response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000143" ; a owl:Class ; rdfs:label "organism UV response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, obo:WBPhenotype_0001897, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009411 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009411 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000144 obo:IAO_0000115 "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000144" ; a owl:Class ; rdfs:label "pathogen induced cell death increased" ; rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0001269 . obo:WBPhenotype_0000145 obo:IAO_0000115 "Animals exhibit variations in the time of onset or duration of the fertile period, or production of new individuals that contain some portion of their genetic material inherited from that organism compared to control." ; oboInOwl:hasExactSynonym "fertility variant" ; oboInOwl:hasNarrowSynonym "fertility abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000145" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "fertility phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000613, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000274 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000274 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000146 obo:IAO_0000115 "Animals do not respond to changes in temperature or thermal stress in the same manner as control animals. In C.elegans this is often measured by changes in the expression of stress proteins or changes in life span." ; oboInOwl:hasNarrowSynonym "organism temperature response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000146" ; a owl:Class ; rdfs:label "organism temperature response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009266 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009266 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000147 obo:IAO_0000115 "Any variation in the state or activity of an organism as a result of deprivation of nourishment, compared to control." ; oboInOwl:hasNarrowSynonym "organism starvation response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000147" ; a owl:Class ; rdfs:label "organism starvation response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042594 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042594 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000148 obo:IAO_0000115 "Animals exhibit variations in the entry into the dauer stage when exposed to nutrient poor conditions that induce dauer formation in control animals." ; oboInOwl:hasNarrowSynonym "starvation induced dauer formation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000148" ; a owl:Class ; rdfs:label "starvation induced dauer formation variant" ; rdfs:subClassOf obo:WBPhenotype_0000147, obo:WBPhenotype_0001539 . obo:WBPhenotype_0000149 obo:IAO_0000115 "Animals are more likely to form dauers under nutrient conditions that do not induce dauer entry in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000149" ; a owl:Class ; rdfs:label "starvation induced dauer formation increased" ; rdfs:subClassOf obo:WBPhenotype_0000148 . obo:WBPhenotype_0000150 obo:IAO_0000115 "Animals do not enter dauer under nutrient-poor conditions that induce dauer formation in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000150" ; a owl:Class ; rdfs:label "starvation induced dauer formation defective" ; rdfs:subClassOf obo:WBPhenotype_0000013, obo:WBPhenotype_0000148 . obo:WBPhenotype_0000151 obo:IAO_0000115 "Embryos generate an excess number of anterior derived pharyngeal cells. In C. elegans, embryos generate an excess number of AB blastomere-derived pharyngeal cells. This hyperinduction of anterior pharyngeal tissue is associated with defects in fate specification of the ABp blastomere." ; oboInOwl:hasBroadSynonym "Apx" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000151" ; a owl:Class ; rdfs:label "anterior pharynx extra cells" ; rdfs:subClassOf obo:WBPhenotype_0000115, obo:WBPhenotype_0002175 . obo:WBPhenotype_0000152 obo:IAO_0000115 "One-cell embryos do not form the shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000152" ; a owl:Class ; rdfs:label "no cleavage furrow first division early emb" ; rdfs:subClassOf obo:WBPhenotype_0001129 . obo:WBPhenotype_0000153 obo:IAO_0000115 "Initiation, strength, extent or cessation of body wall muscle activity that results in the shortening of the muscle, is aberrant compared to control animals." ; oboInOwl:hasExactSynonym "body wall contraction variant" ; oboInOwl:hasNarrowSynonym "body wall contraction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000153" ; a owl:Class ; rdfs:label "body wall muscle contraction abnormal" ; rdfs:subClassOf obo:WBPhenotype_0000596, obo:WBPhenotype_0000611, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0006936 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005813 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0006936 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005813 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000154 obo:IAO_0000115 "The characteristic number of offspring produced is lower compared to that of control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000154" ; a owl:Class ; rdfs:label "reduced brood size" ; rdfs:subClassOf obo:WBPhenotype_0000673 . obo:WBPhenotype_0000155 obo:IAO_0000115 "Contents or structures of the cell are oriented on the opposite side of the cell compared to control animals; In C. elegans, this can result in the fate pattern of descendants being flipped." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000155" ; a owl:Class ; rdfs:label "cell polarity reversed" ; rdfs:subClassOf obo:WBPhenotype_0000104 . obo:WBPhenotype_0000156 obo:IAO_0000115 "Any variation in the time interval between successive contractions of the body wall muscles during the defecation motor program compared to cantrol." ; oboInOwl:hasNarrowSynonym "body wall contraction interval abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "body wall muscle contraction interval abnormal" ; oboInOwl:id "WBPhenotype:0000156" ; a owl:Class ; rdfs:label "body wall muscle contraction interval during defecation abnormal" ; rdfs:subClassOf obo:WBPhenotype_0000210 . obo:WBPhenotype_0000157 obo:IAO_0000115 "Animals exhibit variations in the sustained posterior body muscle contractions that precede the remaining contractions of the defecation cycle compared to control animals." ; oboInOwl:hasBroadSynonym "pBoc" ; oboInOwl:hasNarrowSynonym "posterior body wall contraction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "posterior body contraction abnormal", "posterior body wall contraction defective" ; oboInOwl:id "WBPhenotype:0000157" ; a owl:Class ; rdfs:label "posterior body wall contraction defecation cycle variant" ; rdfs:subClassOf obo:WBPhenotype_0000210 . obo:WBPhenotype_0000158 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000209 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000158" ; a owl:Class ; rdfs:label "obsolete posterior body wall shortened interval" ; owl:deprecated true . obo:WBPhenotype_0000159 obo:IAO_0000115 "OBSOLETE: Animals exhibit variations in the entry/exit into a state of arrested tissue development during the dauer larval stage in response to harsh environmental conditions, compared to control. In C. elegans, the dauer larva enters a state of arrest in which no developmental changes occur, until the animal finds more suitable growing conditions, or until it spontaneously shifts back into a normal developmental schedule. (WormAtlas)." ; obo:IAO_0100001 obo:WBPhenotype_0000308 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000159" ; a owl:Class ; rdfs:label "obsolete dauer arrest variant" ; owl:deprecated true . obo:WBPhenotype_0000160 obo:IAO_0000115 "Embryos do not form a defined shallow groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000160" ; a owl:Class ; rdfs:label "cleavage furrow not discrete early emb" ; rdfs:subClassOf obo:WBPhenotype_0001129 . obo:WBPhenotype_0000161 obo:IAO_0000115 "Any variation in the rotation of centrosomes and associated pronuclei in one-cell embryo, occurring as a transition between pronuclear migration and pronuclear fusion compared to control." ; oboInOwl:hasNarrowSynonym "nuclear rotation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000161" ; a owl:Class ; rdfs:label "nuclear rotation variant" ; rdfs:subClassOf obo:WBPhenotype_0000749, obo:WBPhenotype_0001028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001599 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001599 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000162 obo:IAO_0000115 "Larva show deficiencies in chroma resulting in increased translucency." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "translucent" ; oboInOwl:id "WBPhenotype:0000162" ; a owl:Class ; rdfs:label "pale larva" ; rdfs:subClassOf obo:WBPhenotype_0000890, obo:WBPhenotype_0001261, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000328 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000328 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] . obo:WBPhenotype_0000163 obo:IAO_0000115 "Larva appear unusually transparent when compared to control." ; oboInOwl:hasBroadSynonym "Clr" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "transparent" ; oboInOwl:id "WBPhenotype:0000163" ; a owl:Class ; rdfs:label "clear larva" ; rdfs:subClassOf obo:WBPhenotype_0000890, obo:WBPhenotype_0001010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000964 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000964 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] . obo:WBPhenotype_0000164 obo:IAO_0000115 "Animals exhibit a reduced girth compared to a control animal of the same developmental stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "decreased girth", "slim" ; oboInOwl:id "WBPhenotype:0000164" ; a owl:Class ; rdfs:label "thin" ; rdfs:subClassOf obo:WBPhenotype_0001727, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000592 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000592 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] . obo:WBPhenotype_0000165 obo:IAO_0000115 "Variations in the ability of two or more individual cells to form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes. Cell fusion is dependent on the merging of lipid bilayer membranes as well as cytoplasmic mixing." ; oboInOwl:hasNarrowSynonym "cell fusion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000165" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell fusion variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000768 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000768 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000166 obo:IAO_0000115 "Variations in the ability of seam cells to fuse to form a continuous syncytium along the body wall late larval development, (separate from the hyp 7 syncytium), compared to control (WormAtlas). Hypodermal seam cells lie along the lateral body wall to form longitudinal stripes of epithelial cells underlying the alae, and are required for alae formation." ; oboInOwl:hasNarrowSynonym "seam cell fusion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000166" ; a owl:Class ; rdfs:label "seam cell fusion variant" ; rdfs:subClassOf obo:WBPhenotype_0000165 . obo:WBPhenotype_0000167 obo:IAO_0000115 "Seam cells fuse to form a continuous syncytium along the body wall at an earlier stage of development compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000167" ; a owl:Class ; rdfs:label "precocious seam cell fusion" ; rdfs:subClassOf obo:WBPhenotype_0000166, obo:WBPhenotype_0001433 . obo:WBPhenotype_0000168 obo:IAO_0000115 "Variations in the regulated release of proteins needed for alae formation by epidermal seam cells compared to control. Alae are small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (WormAtlas)." ; oboInOwl:hasNarrowSynonym "alae secretion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "alae formation variant" ; oboInOwl:id "WBPhenotype:0000168" ; a owl:Class ; rdfs:label "alae secretion variant" ; rdfs:subClassOf obo:WBPhenotype_0000258, obo:WBPhenotype_0000608, obo:WBPhenotype_0001210, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007832 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0046903 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007832 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000169 obo:IAO_0000115 "Cells leave the M phase (mitosis and cytokinesis) at an earlier time than sister or other control cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000169" ; a owl:Class ; rdfs:label "early exit cell cycle" ; rdfs:subClassOf obo:WBPhenotype_0001995 . obo:WBPhenotype_0000170 obo:IAO_0000115 "Formation of alae occurs earlier in development compared to control animals; In C. elegans, adult lateral alae are typically generated during the late L4 stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000170" ; a owl:Class ; rdfs:label "precocious alae" ; rdfs:subClassOf obo:WBPhenotype_0000168, obo:WBPhenotype_0000439 . obo:WBPhenotype_0000171 obo:IAO_0000115 "Any aberrancy in the processes that govern expansion of cell populations compared to control animals." ; oboInOwl:hasNarrowSynonym "cell proliferation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000171" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell proliferation variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000172 obo:IAO_0000115 "The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are increased." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000172" ; a owl:Class ; rdfs:label "cell proliferation increased" ; rdfs:subClassOf obo:WBPhenotype_0000171, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000173 obo:IAO_0000115 "The processes governing the expansion of cell populations are altered compared to control animals, such that cell populations are decreased." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000173" ; a owl:Class ; rdfs:label "cell proliferation reduced" ; rdfs:subClassOf obo:WBPhenotype_0000171, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002052 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002052 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000174 obo:IAO_0000115 "Any variation in the progression of the layer of connective tissue over the surface of tissues that serves to separate it from neighboring tissues, from its formation to its mature structure compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "basal lamina development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000174" ; a owl:Class ; rdfs:label "basal lamina development variant" ; rdfs:subClassOf obo:WBPhenotype_0000619, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005756 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005756 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000175 obo:IAO_0000115 "Excessive and often uncoordinated body wall muscle contraction leading to shortening of the body." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000175" ; a owl:Class ; rdfs:label "hypercontracted" ; rdfs:subClassOf obo:WBPhenotype_0000001 . obo:WBPhenotype_0000176 obo:IAO_0000115 "Any variation in the specific actions or reactions of an animal after completion of feeding, typically after a fast, compared to that observed in control animals. In C. elegans worms become behaviorally quiescent and cease feeding and moving when sated." ; oboInOwl:hasNarrowSynonym "satiety behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000176" ; a owl:Class ; rdfs:label "satiety behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000659 . obo:WBPhenotype_0000177 obo:IAO_0000115 "Any variation that results in a decrease of acetylcholine esterase levels, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000177" ; a owl:Class ; rdfs:label "acetylcholinesterase reduced" ; rdfs:subClassOf obo:WBPhenotype_0000124 . obo:WBPhenotype_0000178 obo:IAO_0000115 "Cells are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000178" ; a owl:Class ; rdfs:label "cell degeneration" ; rdfs:subClassOf obo:WBPhenotype_0000533, obo:WBPhenotype_0000729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000639 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000639 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000179 obo:IAO_0000115 "Cells specialized for receiving, conducting and transmitting impulses in the nervous system are observed to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000179" ; a owl:Class ; rdfs:label "neuron degeneration" ; rdfs:subClassOf obo:WBPhenotype_0000178, obo:WBPhenotype_0000905, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000639 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000639 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000180 obo:IAO_0000115 "Animals display variations in the structure, organization of components, or spatial pattern of the projection that conducts signal away from the cell body, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "axon morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000180" ; a owl:Class ; rdfs:label "axon morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001398, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030424 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030424 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000181 obo:IAO_0000115 "Animals display variations in the directed path taken by the axon compared to the path the nerve fiber follows in the nervous system in control animals." ; oboInOwl:hasNarrowSynonym "axon trajectory abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000181" ; a owl:Class ; rdfs:label "axon trajectory variant" ; rdfs:subClassOf obo:WBPhenotype_0000180, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000133 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030424 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000133 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030424 ] ) ] ] . obo:WBPhenotype_0000182 obo:IAO_0000115 "Any perturbation that causes a decrease in the frequency of cell death by apoptosis compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000182" ; a owl:Class ; rdfs:label "apoptosis reduced" ; rdfs:subClassOf obo:WBPhenotype_0000730, obo:WBPhenotype_0002620, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002052 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002052 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000183 obo:IAO_0000115 "Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000183" ; a owl:Class ; rdfs:label "apoptosis increased" ; rdfs:subClassOf obo:WBPhenotype_0000730, obo:WBPhenotype_0002619, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000184 obo:IAO_0000115 "Cells do not undergo the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000184" ; a owl:Class ; rdfs:label "apoptosis fails to occur" ; rdfs:subClassOf obo:WBPhenotype_0000182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000185 obo:IAO_0000115 "Animals exhibit a decreased pace of the programmed cell death pathway, compared to that observed for control cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000185" ; a owl:Class ; rdfs:label "apoptosis protracted" ; rdfs:subClassOf obo:WBPhenotype_0000730 . obo:WBPhenotype_0000186 obo:IAO_0000115 "Any aberrancy in the processes that influence the generation and maturation of oocytes compared to control animals." ; oboInOwl:hasAlternativeId "WBPhenotype:0000896" ; oboInOwl:hasExactSynonym "oocyte germ cell differentiation abnormal" ; oboInOwl:hasNarrowSynonym "oogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "oocyte development abnormal" ; oboInOwl:id "WBPhenotype:0000186" ; a owl:Class ; rdfs:label "oogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000812, obo:WBPhenotype_0000894, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048599 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048599 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000187 obo:IAO_0000115 "The overall structure or appearance of fertilized oocytes that are laid has every part of their surface equidistant from the center." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000187" ; a owl:Class ; rdfs:label "egg round" ; rdfs:subClassOf obo:WBPhenotype_0000373 . obo:WBPhenotype_0000188 obo:IAO_0000115 "Any variation in the 'arm-like' form, structure or composition of the specialized tissue of the reproductive tract that produces gametes compared to control. In C. elegans the reproductive tract in the hermaphrodite has two equivalent gonad 'arms', while the male has a one-armed gonad." ; oboInOwl:hasNarrowSynonym "gonad arm morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000188" ; a owl:Class ; rdfs:label "gonad arm morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000977 . obo:WBPhenotype_0000189 obo:IAO_0000115 "Hypodermal cells fail to be organized in the same manner as observed in control animals. In C. elegans, hypodermal cells typically organize into distinct dorsal, lateral and ventral rows and cover the entire body." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000189" ; a owl:Class ; rdfs:label "hypodermis disorganized" ; rdfs:subClassOf obo:WBPhenotype_0000703, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000937 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005733 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000937 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005733 ] ) ] ] . obo:WBPhenotype_0000190 obo:IAO_0000115 "Animals fail to exit from the facultative diapause of the dauer larval stage of nematode development." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000190" ; a owl:Class ; rdfs:label "no dauer recovery" ; rdfs:subClassOf obo:WBPhenotype_0000127, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043054 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043054 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000191 obo:IAO_0000115 "Animals exhibit variations in their response to a situation when there is too high a density of nematodes to be supported by the available amount of food and space compared to that observed in control animals (Wormatlas)." ; oboInOwl:hasNarrowSynonym "organism crowding response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000191" ; a owl:Class ; rdfs:label "organism crowding response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0090664 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0090664 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000192 obo:IAO_0000115 "Any variation that results in the misregulation of enzymatic activity such that catalysis occurs at a constant rate regardless of physiological demand or the concentration of a substrate." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000192" ; a owl:Class ; rdfs:label "constitutive enzyme activity" ; rdfs:subClassOf obo:WBPhenotype_0000125 . obo:WBPhenotype_0000193 obo:IAO_0000115 "Any variation within an enzyme that causes it to act antagonistically towards the wild-type enzymatic product. These mutations usually result in an altered molecular function (often inactive) and are characterized by a dominant or semi-dominant phenotype." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000193" ; a owl:Class ; rdfs:label "dominant negative enzyme" ; rdfs:subClassOf obo:WBPhenotype_0000727 . obo:WBPhenotype_0000194 obo:IAO_0000115 "Variations in the placement of the polar body formed in the first division of meiosis of a primary oocyte, compared to control. A polar body is the by-product of meiosis (destined to degenerate) in female or hermaphrodite animals." ; oboInOwl:hasNarrowSynonym "first polar body position abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000194" ; a owl:Class ; rdfs:label "first polar body position variant" ; rdfs:subClassOf obo:WBPhenotype_0000775 . obo:WBPhenotype_0000195 obo:IAO_0000115 "Variations in the migration pattern of distal tip cells compared to control animals. In C. elegans, DTCs located on the anterior and posterior ends of the gonad primordium typically migrate in a symmetrical U-shaped pattern." ; oboInOwl:hasNarrowSynonym "distal tip cell migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "DTC migration abnormal" ; oboInOwl:id "WBPhenotype:0000195" ; a owl:Class ; rdfs:label "distal tip cell migration variant" ; rdfs:subClassOf obo:WBPhenotype_0000594 . obo:WBPhenotype_0000196 obo:IAO_0000115 "The morphological appearance of distal tip cells is varied compared to control animals." ; oboInOwl:hasNarrowSynonym "distal tip cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000196" ; a owl:Class ; rdfs:label "distal tip cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006865 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006865 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000197 obo:IAO_0000115 "Variations in a cell's ability to influence the fate of another cell (often of different developmental potential or ancestry via short range signaling)." ; oboInOwl:hasNarrowSynonym "cell induction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000197" ; a owl:Class ; rdfs:label "cell induction variant" ; rdfs:subClassOf obo:WBPhenotype_0000216, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031129 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031129 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000198 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0001272 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000198" ; a owl:Class ; rdfs:label "obsolete vulval cell induction abnormal" ; owl:deprecated true . obo:WBPhenotype_0000199 obo:IAO_0000115 "Any variation in the progression of the finger-like sensory sensilla that project from the tail and embed in the male fan from its formation to the mature structure when compared to control animals." ; oboInOwl:hasNarrowSynonym "male tail sensory ray development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000199" ; a owl:Class ; rdfs:label "male tail sensory ray development variant" ; rdfs:subClassOf obo:WBPhenotype_0000930, obo:WBPhenotype_0001008, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006941 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006941 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000200 obo:IAO_0000115 "Variations in the progression of structures/tissues surrounding a cell over time from its initial formation to its mature form compared to control." ; oboInOwl:hasNarrowSynonym "pericellular component development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000200" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "pericellular component development variant" ; rdfs:subClassOf obo:WBPhenotype_0000518, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:GO_0031012 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:GO_0031012 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000201 obo:IAO_0000115 "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time compared to control animals (Wormatlas)." ; oboInOwl:hasNarrowSynonym "cuticle development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000201" ; a owl:Class ; rdfs:label "cuticle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000200, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042335 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042335 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000202 obo:IAO_0000115 "Any variation in the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "alae abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000202" ; a owl:Class ; rdfs:label "alae variant" ; rdfs:subClassOf obo:WBPhenotype_0000201 . obo:WBPhenotype_0000203 obo:IAO_0000115 "Animals exhibit variations in the characteristic desensitization to a volatile organic chemo-attractive signal in a time-concentration dependent and reversible manner compared to control animals." ; oboInOwl:hasNarrowSynonym "odorant adaptation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000203" ; a owl:Class ; rdfs:label "odorant adaptation variant" ; rdfs:subClassOf obo:WBPhenotype_0001048 . obo:WBPhenotype_0000204 obo:IAO_0000115 "Variations in the anterior body muscle contraction (aBoc) step of the defecation cycle compared to control animals. Under normal conditions, anterior body wall muscles contract and pressurize the intestinal contents during the aBoc step." ; oboInOwl:hasBroadSynonym "aBoc" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "anterior body contraction abnormal", "anterior body contraction defective" ; oboInOwl:id "WBPhenotype:0000204" ; a owl:Class ; rdfs:label "anterior body contraction defecation cycle variant" ; rdfs:subClassOf obo:WBPhenotype_0001476 . obo:WBPhenotype_0000205 obo:IAO_0000115 "Any variation in the expulsion of gut contents compared to control. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion." ; oboInOwl:hasNarrowSynonym "expulsion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Exp" ; oboInOwl:id "WBPhenotype:0000205" ; a owl:Class ; rdfs:label "expulsion variant" ; rdfs:subClassOf obo:WBPhenotype_0000210 . obo:WBPhenotype_0000206 obo:IAO_0000115 "A non-sex chromosome fails to segregate away from its homologous chromosome, resulting in gametes with no or extra copies of the non-sex homolog." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000206" ; a owl:Class ; rdfs:label "autosomal nondisjunction meiosis" ; rdfs:subClassOf obo:WBPhenotype_0001174 . obo:WBPhenotype_0000207 obo:IAO_0000115 "Any variation in the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control ." ; oboInOwl:hasNarrowSynonym "defecation cycle abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Dec" ; oboInOwl:id "WBPhenotype:0000207" ; a owl:Class ; rdfs:label "defecation cycle variant" ; rdfs:subClassOf obo:WBPhenotype_0000650, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035882 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035882 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000208 obo:IAO_0000115 "The mean time between the onset of the defecation motor program is greater than that observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Dec-l", "reduced rate of defecation" ; oboInOwl:id "WBPhenotype:0000208" ; a owl:Class ; rdfs:label "long defecation cycle" ; rdfs:subClassOf obo:WBPhenotype_0000207 . obo:WBPhenotype_0000209 obo:IAO_0000115 "The mean time between the onset of the defecation motor program is shorter than that observed for control animals." ; oboInOwl:hasExactSynonym "posterior body wall shortened interval" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Dec-s", "fast Dec", "increased rate of defecation" ; oboInOwl:id "WBPhenotype:0000209" ; a owl:Class ; rdfs:label "short defecation cycle" ; rdfs:subClassOf obo:WBPhenotype_0000207, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030421 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030421 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000210 obo:IAO_0000115 "Any variation in the stereotyped muscle contractions that result in defecation compared to control . In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp)." ; oboInOwl:hasNarrowSynonym "defecation contraction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000210" ; a owl:Class ; rdfs:label "defecation contraction variant" ; rdfs:subClassOf obo:WBPhenotype_0000650 . obo:WBPhenotype_0000211 obo:IAO_0000115 "The rhythmic contractions of the muscles coordinating the elimination of gut contents are no longer synchronized compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "defecation contraction mistimed" ; oboInOwl:id "WBPhenotype:0000211" ; a owl:Class ; rdfs:label "defecation contraction asynchronous" ; rdfs:subClassOf obo:WBPhenotype_0000210 . obo:WBPhenotype_0000212 obo:IAO_0000115 "Animals contain body regions that are more narrow or drawn together than adjacent body regions." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000212" ; a owl:Class ; rdfs:label "body constriction" ; rdfs:subClassOf obo:WBPhenotype_0000072 . obo:WBPhenotype_0000213 obo:IAO_0000115 "Variations in the progression of a zygote from formation (gamete fusion) to just prior to the first cell division compared to control." ; oboInOwl:hasNarrowSynonym "zygotic development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000213" ; a owl:Class ; rdfs:label "zygotic development variant" ; rdfs:subClassOf obo:WBPhenotype_0000749, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0004422 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0004422 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000214 obo:IAO_0000115 "Animals respond to alpha amanitin at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000214" ; a owl:Class ; rdfs:label "alpha amanitin hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_37415 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_37415 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000215 obo:IAO_0000115 "Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline." ; oboInOwl:hasExactSynonym "no germline" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000215" ; a owl:Class ; rdfs:label "no germ line" ; rdfs:subClassOf obo:WBPhenotype_0000812, obo:WBPhenotype_0002556, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005784 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005784 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000216 obo:IAO_0000115 "Any variation in the processes that govern acquisition of particular cell fates compared to control animals." ; oboInOwl:hasNarrowSynonym "cell fate specification abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000216" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell fate specification variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0001708 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0001708 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000217 obo:IAO_0000115 "The time in which a muscle contraction event that controls feeding is increased compared to control. Contractions of the pharynx are necessary for bacterial uptake from the surrounding environment." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000217" ; a owl:Class ; rdfs:label "prolonged pharyngeal contraction" ; rdfs:subClassOf obo:WBPhenotype_0000980 . obo:WBPhenotype_0000218 obo:IAO_0000115 "An excess number of vulval precursor cells receive an inductive signal leading to an increased number of VPCs adopting vulval fates compared to control animals." ; oboInOwl:hasBroadSynonym "Hin" ; oboInOwl:hasNarrowSynonym "overinduced" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000218" ; a owl:Class ; rdfs:label "vulval cell induction increased" ; rdfs:subClassOf obo:WBPhenotype_0001272 . obo:WBPhenotype_0000219 obo:IAO_0000115 "Vulval precursor cells receive a decrease in inductive signal leading to fewer VPCs adopting vulval fates compared to control animals." ; oboInOwl:hasNarrowSynonym "underinduced" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000219" ; a owl:Class ; rdfs:label "vulval cell induction reduced" ; rdfs:subClassOf obo:WBPhenotype_0001272 . obo:WBPhenotype_0000220 obo:IAO_0000115 "Any aberrancy in the processes that govern acquisition of vulval cell fates compared to control animals." ; oboInOwl:hasNarrowSynonym "vulva cell fate specification abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000220" ; a owl:Class ; rdfs:label "vulva cell fate specification variant" ; rdfs:subClassOf obo:WBPhenotype_0000216, obo:WBPhenotype_0000699 . obo:WBPhenotype_0000221 obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving neurotransmitters compared to control animals. Neurotransmitters are any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell." ; oboInOwl:hasNarrowSynonym "neurotransmitter metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000221" ; a owl:Class ; rdfs:label "neurotransmitter metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042133 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042133 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000222 obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter, compared to control." ; oboInOwl:hasNarrowSynonym "serotonin metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000222" ; a owl:Class ; rdfs:label "serotonin metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000221, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042428 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042428 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000223 obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving acetylcholine, compared to control. Acetylcholine is the acetic acid ester of the organic base choline." ; oboInOwl:hasNarrowSynonym "acetylcholine metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000223" ; a owl:Class ; rdfs:label "acetylcholine metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000221, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008291 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008291 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000224 obo:IAO_0000115 "Animals do not contain or are unable to maintain a perceivable level of serotonin capable of initiating or maintaining serotonin-dependent cell activity." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000224" ; a owl:Class ; rdfs:label "serotonin deficient" ; rdfs:subClassOf obo:WBPhenotype_0000222 . obo:WBPhenotype_0000225 obo:IAO_0000115 "Animals are unable to carry out the chemical reactions and pathways resulting in the formation of serotonin." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000225" ; a owl:Class ; rdfs:label "serotonin synthesis defective" ; rdfs:subClassOf obo:WBPhenotype_0000222, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042427 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042427 ] ) ] ] . obo:WBPhenotype_0000226 obo:IAO_0000115 "Animals are unable to carry out any chemical reaction or pathway resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000226" ; a owl:Class ; rdfs:label "serotonin catabolism defective" ; rdfs:subClassOf obo:WBPhenotype_0000222, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042429 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042429 ] ) ] ] . obo:WBPhenotype_0000227 obo:IAO_0000115 "The inability of a male to properly turn during mating behavior. In C. elegans, males typically turn via a sharp ventral arch of the tail, as he approaches either the hermaphrodite head or tail." ; oboInOwl:hasNarrowSynonym "male turning abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000227" ; a owl:Class ; rdfs:label "male turning defective" ; rdfs:subClassOf obo:WBPhenotype_0004006 . obo:WBPhenotype_0000228 obo:IAO_0000115 "Animals accumulate a greater number of genetic lesions than control animals in the absence of an externally controlled mutagen. In C. elegans, this is often measured by observing the number of reversion events of a known mutant gene function over a couple generations." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000228" ; a owl:Class ; rdfs:label "spontaneous mutation rate increased" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0000229 obo:IAO_0000115 "Animals are shorter and thinner than control animals at the same developmental stage." ; oboInOwl:hasExactSynonym "body size reduced" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Sma" ; oboInOwl:id "WBPhenotype:0000229" ; a owl:Class ; rdfs:label "small" ; rdfs:subClassOf obo:WBPhenotype_0001726, obo:WBPhenotype_0001727, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000230 obo:IAO_0000115 "The girth of the region posterior to the vulva is reduced compared to that anterior to the vulva (the Wit phenotype). In C. elegans this phenotype is associated with anteriorward misplacement of the CAN neurons." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Wit" ; oboInOwl:id "WBPhenotype:0000230" ; a owl:Class ; rdfs:label "tail withered" ; rdfs:subClassOf obo:WBPhenotype_0000073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000585 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000585 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] ) ] ] . obo:WBPhenotype_0000231 obo:IAO_0000115 "Animals exhibit variations in the physical dimensions of its body compared to control animals of the same developmental stage." ; oboInOwl:hasNarrowSynonym "body size abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000231" ; a owl:Class ; rdfs:comment "PATO:0000117." ; rdfs:label "body size variant" ; rdfs:subClassOf obo:WBPhenotype_0000072 . obo:WBPhenotype_0000232 obo:IAO_0000115 "Variation in the migration pattern of CAN neurons. In C. elegans, CAN neurons move posteriorly from their birthplace in the head to positions near the middle of the embryo." ; oboInOwl:hasNarrowSynonym "CAN cell migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000232" ; a owl:Class ; rdfs:label "CAN cell migration variant" ; rdfs:subClassOf obo:WBPhenotype_0001520 . obo:WBPhenotype_0000233 obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline, compared to control." ; oboInOwl:hasNarrowSynonym "dopamine metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000233" ; a owl:Class ; rdfs:label "dopamine metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000221, obo:WBPhenotype_0001518, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042417 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042417 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000234 obo:IAO_0000115 "Animals do not contain or are unable to maintain a the level of dopamine capable of initiating or maintaining dopamine-dependent cell activity compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "dopamine levels decreased" ; oboInOwl:id "WBPhenotype:0000234" ; a owl:Class ; rdfs:label "dopamine deficient" ; rdfs:subClassOf obo:WBPhenotype_0000233 . obo:WBPhenotype_0000235 obo:IAO_0000115 "Animals are unable to carry out the chemical reactions and pathways resulting in the formation of dopamine." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000235" ; a owl:Class ; rdfs:label "dopamine synthesis defective" ; rdfs:subClassOf obo:WBPhenotype_0000233, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042416 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042416 ] ) ] ] . obo:WBPhenotype_0000236 obo:IAO_0000115 "Animals are unable to carry outany chemical reaction or pathway resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000236" ; a owl:Class ; rdfs:label "dopamine catabolism defective" ; rdfs:subClassOf obo:WBPhenotype_0000233, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042420 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042420 ] ) ] ] . obo:WBPhenotype_0000237 obo:IAO_0000115 "Animals extend intensity of roaming and or dwelling activity compared to control animals. In C. elegans, hyperactivity may include an increase in nose-lifts per minute." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000237" ; a owl:Class ; rdfs:label "foraging hyperactive" ; rdfs:subClassOf obo:WBPhenotype_0000662, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060756 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060756 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000238 obo:IAO_0000115 "Animals decrease intensity or rate of roaming and or dwelling activity compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000238" ; a owl:Class ; rdfs:label "foraging reduced" ; rdfs:subClassOf obo:WBPhenotype_0000662, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060756 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060756 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000239 obo:IAO_0000115 "The descendants of a vulval precursor cell exhibit altered developmental programs compared to their counterparts in control animals. In C. elegans, the VPCs are P3.p-P8.p." ; oboInOwl:hasNarrowSynonym "vulval cell lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "VPC lineage abnormal" ; oboInOwl:id "WBPhenotype:0000239" ; a owl:Class ; rdfs:label "vulval cell lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000099 . obo:WBPhenotype_0000240 obo:IAO_0000115 "The processes governing the expansion of blast cell populations vary, such that cell populations are decreased compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000240" ; a owl:Class ; rdfs:label "blast cell proliferation reduced" ; rdfs:subClassOf obo:WBPhenotype_0000173 . obo:WBPhenotype_0000241 obo:IAO_0000115 "Animals exhibit an increase in the quantity of cells that have undergone programmed cell death but have not been engulfed." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000241" ; a owl:Class ; rdfs:label "accumulated cell corpses" ; rdfs:subClassOf obo:WBPhenotype_0000590 . obo:WBPhenotype_0000242 obo:IAO_0000115 "The epidermal cells of the embryo fail to elongate. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000242" ; a owl:Class ; rdfs:label "body elongation defective" ; rdfs:subClassOf obo:WBPhenotype_0001478 . obo:WBPhenotype_0000243 obo:IAO_0000115 "Removal of cell corpses through a dedicated engulfment pathway is defective." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "corpse engulfment defective", "persistent cell corpses" ; oboInOwl:id "WBPhenotype:0000243" ; a owl:Class ; rdfs:label "engulfment failure by killer cell" ; rdfs:subClassOf obo:WBPhenotype_0000885 . obo:WBPhenotype_0000244 obo:IAO_0000115 "Cells fail to complete the form of programmed cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), classically little or no ultrastructural modifications of cytoplasmic organelles, plasma membrane blebbing (but maintenance of its integrity until the final stages of the process) and engulfment by resident phagocytes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "apoptosis block" ; oboInOwl:id "WBPhenotype:0000244" ; a owl:Class ; rdfs:label "apoptotic arrest" ; rdfs:subClassOf obo:WBPhenotype_0000182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000245 obo:IAO_0000115 "Variations in the movement of sex myoblasts compared to control animals. In C. elegans, the larval SM migrate anteriorly to the precise center of the developing hermaphrodite gonad." ; oboInOwl:hasNarrowSynonym "SM migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000245" ; a owl:Class ; rdfs:label "SM migration variant" ; rdfs:subClassOf obo:WBPhenotype_0001230 . obo:WBPhenotype_0000246 obo:IAO_0000115 "Animals exhibit variation in the time of onset of the defecation motor program significantly greater than that observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000246" ; a owl:Class ; rdfs:label "defecation cycle variable length" ; rdfs:subClassOf obo:WBPhenotype_0000207 . obo:WBPhenotype_0000247 obo:IAO_0000115 "Failure to execute the characteristic response to sodium as defined by control animals. In C. elegans, sodium is typically an attractant." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Na chemotaxis defective", "sodium acetate chemotaxis defective" ; oboInOwl:id "WBPhenotype:0000247" ; a owl:Class ; rdfs:label "sodium chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001440, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_26708 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_26708 ] ) ] ] . obo:WBPhenotype_0000248 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000652 ; oboInOwl:hasNarrowSynonym "sensory neuroanatomy abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000248" ; a owl:Class ; rdfs:label "obsolete sensory neuroanatomy variant" ; owl:deprecated true . obo:WBPhenotype_0000249 obo:IAO_0000115 "Failure to execute the characteristic avoidance response to solutions of high osmotic strength as defined by control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000249" ; a owl:Class ; rdfs:label "osmotic avoidance defective" ; rdfs:subClassOf obo:WBPhenotype_0000663 . obo:WBPhenotype_0000250 obo:IAO_0000115 "Animals exhibit variations in any chemical reaction or pathway involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol, compared to control." ; oboInOwl:hasNarrowSynonym "octopamine metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000250" ; a owl:Class ; rdfs:label "octopamine metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000221, obo:WBPhenotype_0001518, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0046333 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0046333 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000251 obo:IAO_0000115 "Animals do not contain or are unable to maintain a perceivable level of octopamine capable of initiating or maintaining dopamine-dependent cell activity." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000251" ; a owl:Class ; rdfs:label "octopamine deficient" ; rdfs:subClassOf obo:WBPhenotype_0000250 . obo:WBPhenotype_0000252 obo:IAO_0000115 "Animals fail to respond to the concentration of caffeine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000252" ; a owl:Class ; rdfs:label "caffeine resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27732 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27732 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000253 obo:IAO_0000115 "Animals exhibit a lack of consistency, regularity, or uniformity while traveling from one location to another." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "movement irregular" ; oboInOwl:id "WBPhenotype:0000253" ; a owl:Class ; rdfs:label "movement erratic" ; rdfs:subClassOf obo:WBPhenotype_0001701, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000330 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007626 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000330 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007626 ] ) ] ] . obo:WBPhenotype_0000254 obo:IAO_0000115 "Failure to execute the characteristic response to chloride. In C. elegans, chloride is typically an attractant." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Cl chemotaxis defective" ; oboInOwl:id "WBPhenotype:0000254" ; a owl:Class ; rdfs:label "chloride chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001439, obo:WBPhenotype_0001458, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_17996 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_17996 ] ) ] ] . obo:WBPhenotype_0000255 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid and phasmid sensilla from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." ; oboInOwl:hasNarrowSynonym "amphid phasmid morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000255" ; a owl:Class ; rdfs:comment "WBbt:0005394, WBbt:0006753." ; rdfs:label "amphid phasmid neuron morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001527 . obo:WBPhenotype_0000256 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the amphid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." ; oboInOwl:hasNarrowSynonym "amphid morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000256" ; a owl:Class ; rdfs:comment "WBbt:0005394." ; rdfs:label "amphid neuron morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000255, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005391 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005391 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000257 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the neuronal cells of the phasmid sensillum, from that observed in control animals. In C. elegans, these neurons are commonly assayed by dye-filling experiments using FITC, DiI or DiO." ; oboInOwl:hasNarrowSynonym "phasmid morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000257" ; a owl:Class ; rdfs:comment "WBbt:0006753." ; rdfs:label "phasmid neuron morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000255, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005425 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005425 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000258 obo:IAO_0000115 "Variations in the regulated release of substances by a cell compared to control." ; oboInOwl:hasAlternativeId "WBPhenotype:0000723" ; oboInOwl:hasExactSynonym "cellular secretion abnormal" ; oboInOwl:hasNarrowSynonym "cell secretion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000258" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell secretion variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032940 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032940 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000259 obo:IAO_0000115 "Variations in the regulated release of substances by nonneuronal cells that enclose or ensheath the tips of the sensory dendrites compared to control." ; oboInOwl:hasNarrowSynonym "sheath cell secretion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000259" ; a owl:Class ; rdfs:label "sheath cell secretion variant" ; rdfs:subClassOf obo:WBPhenotype_0000258 . obo:WBPhenotype_0000260 obo:IAO_0000115 "The regulated release of materials by sheath cells is disrupted." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000260" ; a owl:Class ; rdfs:label "sheath cell secretion failure" ; rdfs:subClassOf obo:WBPhenotype_0000259 . obo:WBPhenotype_0000261 obo:IAO_0000115 "Amphid sheath cells lack the ability to secrete vesicles and their contents within the amphid pocket." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000261" ; a owl:Class ; rdfs:label "amphid sheath secretion failure" ; rdfs:subClassOf obo:WBPhenotype_0000260 . obo:WBPhenotype_0000262 obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the microtubule-based fibrillar bundle (axoneme) that makes up the core of the middle part of the cilium (in a pattern of nine doublet microtubules attached to the membrane and a variable number of smaller singlet microtubules occupying the center). In C. elegans, the axoneme microtubules are arranged in a pattern of nine doublets attached to the membrane with seven smaller singlet microtubules occupying the center." ; oboInOwl:hasNarrowSynonym "axoneme morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000262" ; a owl:Class ; rdfs:label "axoneme morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000615, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005930 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005930 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000263 obo:IAO_0000115 "The microbule-based fibrillar bundle in the core of the cilium is reduced in length compared to axonemes of similar cells in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000263" ; a owl:Class ; rdfs:label "axoneme short" ; rdfs:subClassOf obo:WBPhenotype_0000262, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000574 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005930 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000574 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005930 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000264 obo:IAO_0000115 "Failure to execute the characteristic response to cAMP as defined by control animals. In C. elegans, cAMP is typically an attractant." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000264" ; a owl:Class ; rdfs:label "cAMP chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001463, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_17489 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_17489 ] ) ] ] . obo:WBPhenotype_0000265 obo:IAO_0000115 "Movement towards typically attractive volatile organic chemicals is altered as defined by control animals. In C. elegans, these odorants are typically sensed by the AWA and AWC neurons." ; oboInOwl:hasNarrowSynonym "odorant positive chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000265" ; a owl:Class ; rdfs:label "odorant positive chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000635, obo:WBPhenotype_0001048 . obo:WBPhenotype_0000266 obo:IAO_0000115 "Variations that disrupt stereotypical cleavage patterns (such as cleavage rate, division axes or asymmetric division) compared to control." ; oboInOwl:hasNarrowSynonym "cell cleavage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000266" ; a owl:Class ; rdfs:label "cell cleavage variant" ; rdfs:subClassOf obo:WBPhenotype_0000746 . obo:WBPhenotype_0000267 obo:IAO_0000115 "Any variation that causes a delay in the stereotypical cleavage event compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000267" ; a owl:Class ; rdfs:label "cell cleavage delayed" ; rdfs:subClassOf obo:WBPhenotype_0000266, obo:WBPhenotype_0000438 . obo:WBPhenotype_0000268 obo:IAO_0000115 "Any variation that causes a delay in the stereotypical cleavage pattern of the P cell compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000268" ; a owl:Class ; rdfs:label "P cell cleavage delayed" ; rdfs:subClassOf obo:WBPhenotype_0000267 . obo:WBPhenotype_0000269 obo:IAO_0000115 "OBSOLETE. Animals display a phenotype that has not yet been assigned to a current classification." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000269" ; a owl:Class ; rdfs:label "obsolete unclassified" ; owl:deprecated true . obo:WBPhenotype_0000270 obo:IAO_0000115 "Seemingly unrelated variations that concurrently occur during early embryonic development compared to control animals. In C. elegans, this can include multiple pronuclei, aberrant cytoplasmic texture, decrease in overall pace of development and osmotic sensitivity." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000270" ; a owl:Class ; rdfs:label "pleiotropic defects severe early emb" ; rdfs:subClassOf obo:WBPhenotype_0001007 . obo:WBPhenotype_0000271 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0000318, obo:WBPhenotype_0001995 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000271" ; a owl:Class ; rdfs:label "obsolete cell cycle slow" ; owl:deprecated true . obo:WBPhenotype_0000272 obo:IAO_0000115 "The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate does not conform to the pattern observed in control animals (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000272" ; a owl:Class ; rdfs:label "egg laying irregular" ; rdfs:subClassOf obo:WBPhenotype_0000640, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000044 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000044 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000273 obo:IAO_0000115 "The number of body thrashes within an aqueous environment in a given period of time are reduced compared with control worms." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000273" ; a owl:Class ; rdfs:label "thrashing reduced" ; rdfs:subClassOf obo:WBPhenotype_0001700 . obo:WBPhenotype_0000274 obo:IAO_0000115 "Animals lay eggs that are inviable." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000274" ; a owl:Class ; rdfs:label "dead eggs laid" ; rdfs:subClassOf obo:WBPhenotype_0000640, obo:WBPhenotype_0000806 . obo:WBPhenotype_0000275 obo:IAO_0000115 "Organisms respond to UV at a lower dose or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000275" ; a owl:Class ; rdfs:label "organism UV hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000143 . obo:WBPhenotype_0000276 obo:IAO_0000115 "Animals exhibit variations in their response to X-ray radiation compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "organism X ray response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000276" ; a owl:Class ; rdfs:label "organism X ray response variant" ; rdfs:subClassOf obo:WBPhenotype_0000686, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010165 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010165 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000277 obo:IAO_0000115 "The timing of a biological cycle that recurs with regularity is delayed compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000277" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "rhythm slow" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048511 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048511 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000278 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency or translucency of a particular body region." ; oboInOwl:hasExactSynonym "body region pigmentation abnormal", "body region pigmentation variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000278" ; a owl:Class ; rdfs:label "body region pigmentation phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000521, obo:WBPhenotype_0000532, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005738 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005738 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000279 obo:IAO_0000115 "Males exhibit defects in the insertion of the male copulatory spicules into the mating partner. In C. elegan spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000279" ; a owl:Class ; rdfs:label "spicule insertion defective" ; rdfs:subClassOf obo:WBPhenotype_0001414, obo:WBPhenotype_0004006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034609 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034609 ] ) ] ] . obo:WBPhenotype_0000280 obo:IAO_0000115 "The small linear ridges running along the lateral lines of the cuticle, lengthwise along the body, contain gaps as opposed to a continuous arrangement (Wormatlas)." ; oboInOwl:hasExactSynonym "gapped alae" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000280" ; a owl:Class ; rdfs:label "breaks in alae" ; rdfs:subClassOf obo:WBPhenotype_0001412 . obo:WBPhenotype_0000281 obo:IAO_0000115 "Variations in the progression of the muscles of the adult male reproductive system over time form their initial formation to their mature structure compared to control." ; oboInOwl:hasNarrowSynonym "male sex muscle development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000281" ; a owl:Class ; rdfs:label "male sex muscle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000669 . obo:WBPhenotype_0000282 obo:IAO_0000115 "Variations in the progression of the muscles of the adult hermaphrodite reproductive system over time form their initial formation to their mature structure compared to control." ; oboInOwl:hasNarrowSynonym "hermaphrodite sex muscle development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000282" ; a owl:Class ; rdfs:label "hermaphrodite sex muscle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000669 . obo:WBPhenotype_0000283 obo:IAO_0000115 "Animals exhibit defects in the continuity of lumen between the vulva and uterus compared to control animals." ; oboInOwl:hasNarrowSynonym "AC block" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000283" ; a owl:Class ; rdfs:label "vulva uterus connection defective" ; rdfs:subClassOf obo:WBPhenotype_0000624 . obo:WBPhenotype_0000284 obo:IAO_0000115 "Any defect in the process whereby a male inseminates his partner by introducing sperm into the genital tract." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000284" ; a owl:Class ; rdfs:label "sperm transfer defective" ; rdfs:subClassOf obo:WBPhenotype_0001414, obo:WBPhenotype_0004006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007320 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007320 ] ) ] ] . obo:WBPhenotype_0000285 obo:IAO_0000115 "The extreme ends of any of the finger-like sensory sensilla that project from the tail and embed in the male fan appear bloated or distended." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000285" ; a owl:Class ; rdfs:label "ray tips swollen" ; rdfs:subClassOf obo:WBPhenotype_0000505, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001851 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001851 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] ) ] ] . obo:WBPhenotype_0000286 obo:IAO_0000115 "Embryos fail to be organized in the same manner as observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000286" ; a owl:Class ; rdfs:label "embryo disorganized" ; rdfs:subClassOf obo:WBPhenotype_0000749, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000937 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000003 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000937 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000003 ] ) ] ] . obo:WBPhenotype_0000287 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000510 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000287" ; a owl:Class ; rdfs:label "obsolete vulval invagination L4 abnormal" ; owl:deprecated true . obo:WBPhenotype_0000288 obo:IAO_0000115 "Variations in the progression of the lineages that gives rise to all germ cells, lying in the region adjacent to the proximal gonad (on the side furthest from the founder cells of the somatic gonad), over time compared to control animals." ; oboInOwl:hasNarrowSynonym "distal germline abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "distal germ line abnormal" ; oboInOwl:id "WBPhenotype:0000288" ; a owl:Class ; rdfs:label "distal germline variant" ; rdfs:subClassOf obo:WBPhenotype_0000812 . obo:WBPhenotype_0000289 obo:IAO_0000115 "Any variation in the form, structure or composition of the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "uterus morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000289" ; a owl:Class ; rdfs:label "uterus morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001335, obo:WBPhenotype_0002556, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006760 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006760 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000290 obo:IAO_0000115 "Animals lack fully specialized male gametes that are competent for fertilization." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "no sperm" ; oboInOwl:id "WBPhenotype:0000290" ; a owl:Class ; rdfs:label "sperm absent" ; rdfs:subClassOf obo:WBPhenotype_0000395, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006798 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006798 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000291 obo:IAO_0000115 "Hermaphrodites lack fully specialized female gametes that are competent for fertilization." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "oocytes absent" ; oboInOwl:id "WBPhenotype:0000291" ; a owl:Class ; rdfs:label "no oocytes" ; rdfs:subClassOf obo:WBPhenotype_0000395, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006797 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006797 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000292 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a organ system." ; oboInOwl:hasExactSynonym "organ system pigmentation abnormal", "organ system pigmentation variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000292" ; a owl:Class ; rdfs:label "organ system pigmentation phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000521, obo:WBPhenotype_0000534, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005746 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005746 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000293 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the alimentary system." ; oboInOwl:hasNarrowSynonym "alimentary system pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000293" ; a owl:Class ; rdfs:label "alimentary system pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0000292, obo:WBPhenotype_0000598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000294 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that decrease the transparency/translucency of the intestine." ; oboInOwl:hasBroadSynonym "Din" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000294" ; a owl:Class ; rdfs:label "intestine dark" ; rdfs:subClassOf obo:WBPhenotype_0000293 . obo:WBPhenotype_0000295 obo:IAO_0000115 "Animals are able to survive for longer periods at temperatures above standard culture temperatures than control animals." ; oboInOwl:hasNarrowSynonym "intrinsic thermotolerance increased" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000295" ; a owl:Class ; rdfs:label "thermotolerance increased" ; rdfs:subClassOf obo:WBPhenotype_0000146 . obo:WBPhenotype_0000296 obo:IAO_0000115 "The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) are deformed. In C. elegans males there are two copulatory spicules." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000296" ; a owl:Class ; rdfs:label "spicules crumpled" ; rdfs:subClassOf obo:WBPhenotype_0000443, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001810 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005312 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001810 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005312 ] ) ] ] . obo:WBPhenotype_0000297 obo:IAO_0000115 "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are joined to one another." ; oboInOwl:hasAlternativeId "WBPhenotype:0001241" ; oboInOwl:hasExactSynonym "ray fusion" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000297" ; a owl:Class ; rdfs:label "rays fused" ; rdfs:subClassOf obo:WBPhenotype_0000165, obo:WBPhenotype_0000199, obo:WBPhenotype_0000505, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000642 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0006941 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000642 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0006941 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] ) ] ] . obo:WBPhenotype_0000298 obo:IAO_0000115 "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are shifted from their customary place." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000298" ; a owl:Class ; rdfs:label "rays displaced" ; rdfs:subClassOf obo:WBPhenotype_0000505, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001852 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001852 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] ) ] ] . obo:WBPhenotype_0000299 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals." ; oboInOwl:hasNarrowSynonym "sensillum morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "chemosensory cell morphology abnormal" ; oboInOwl:id "WBPhenotype:0000299" ; a owl:Class ; rdfs:label "sensillum morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000604, obo:WBPhenotype_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000300 obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the amphid sensillum cell that ensheathes the dendrite tips of channel neurons and wing cell dedritic processes, from that observed in control animals. Sheath cells in C.elegans have highly invaginated and vesiculated surfaces, which provide a specialized environment for the dendritic structures." ; oboInOwl:hasNarrowSynonym "amphid sheath cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000300" ; a owl:Class ; rdfs:label "amphid sheath cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000972, obo:WBPhenotype_0001527, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006754 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006754 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000301 obo:IAO_0000115 "A migrating distal tip cell (DTC) fails to follow the stereotypical path. In C. elegans this path is U-shaped and results in the formation of reflexed gonadal arm." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000301" ; a owl:Class ; rdfs:label "distal tip cell reflex failure" ; rdfs:subClassOf obo:WBPhenotype_0000195 . obo:WBPhenotype_0000302 obo:IAO_0000115 "Failure to execute the characteristic response to benzaldehyde as defined by control animals. In C.elegans benzaldehyde is typically attractive." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000302" ; a owl:Class ; rdfs:label "benzaldehyde chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001060, obo:WBPhenotype_0001468, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_22698 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_22698 ] ) ] ] . obo:WBPhenotype_0000303 obo:IAO_0000115 "Failure to execute the characteristic response to diacetyl as defined by control animals. In C.elegans diacetyl is typically attractive." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000303" ; a owl:Class ; rdfs:label "diacetyl chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001470, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_16583 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_16583 ] ) ] ] . obo:WBPhenotype_0000304 obo:IAO_0000115 "Failure to execute the characteristic response to isoamyl alcohol as defined by control animals. In C.elegans isoamyl alcohol is typically attractive." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000304" ; a owl:Class ; rdfs:label "isoamyl alcohol chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001472, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_15837 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_15837 ] ) ] ] . obo:WBPhenotype_0000305 obo:IAO_0000115 "Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that influences behavior in control animals." ; oboInOwl:hasNarrowSynonym "pheromone sensation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000305" ; a owl:Class ; rdfs:label "pheromone sensation variant" ; rdfs:subClassOf obo:WBPhenotype_0000738 . obo:WBPhenotype_0000306 obo:IAO_0000115 "Any variation in the characteristic expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to control animals." ; oboInOwl:hasNarrowSynonym "transgene expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000306" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "transgene expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000717 . obo:WBPhenotype_0000307 obo:IAO_0000115 "Animals fail to detect a pheromone stimulus that induces dauer formation in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000307" ; a owl:Class ; rdfs:label "dauer pheromone sensation defective" ; rdfs:subClassOf obo:WBPhenotype_0001479 . obo:WBPhenotype_0000308 obo:IAO_0000115 "Any variation in the processes that govern development of the dauer larva, a developmentally arrested, larval stage that is specialized for survival under harsh, or otherwise unfavorable, environmental conditions. In C. elegans this is an alternative third larval stage." ; oboInOwl:hasAlternativeId "WBPhenotype:0000159" ; oboInOwl:hasExactSynonym "dauer development abnormal", "dauer development variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "dauer arrest abnormal", "dauer arrest variant", "diapause variant" ; oboInOwl:id "WBPhenotype:0000308" ; a owl:Class ; rdfs:label "dauer development phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000750, obo:WBPhenotype_0002527, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040024 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040024 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000309 obo:IAO_0000115 "Any variation that decreases the ability of dauer larva to tolerate the exposure to sodium dodecyl sulfate (a detergent) compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000309" ; a owl:Class ; rdfs:label "SDS sensitive dauer" ; rdfs:subClassOf obo:WBPhenotype_0001546, obo:WBPhenotype_0001918 . obo:WBPhenotype_0000310 obo:IAO_0000115 "Neurons lack the finger-like dendritic projections, which are observed extending from similar cells in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000310" ; a owl:Class ; rdfs:label "cilia absent" ; rdfs:subClassOf obo:WBPhenotype_0000615, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000311 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000688 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000311" ; a owl:Class ; rdfs:label "obsolete semi sterile" ; owl:deprecated true . obo:WBPhenotype_0000312 obo:IAO_0000115 "Animals are incapable of synthesizing pheromones that induce dauer formation in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000312" ; a owl:Class ; rdfs:label "dauer pheromone production defective" ; rdfs:subClassOf obo:WBPhenotype_0000191, obo:WBPhenotype_0001547 . obo:WBPhenotype_0000313 obo:IAO_0000115 "Developing oocytes show defects in their initial entry or progression through the meiotic pathway (such as failure to exit diakinesis)." ; oboInOwl:hasNarrowSynonym "meiotic progression during oogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000313" ; a owl:Class ; rdfs:label "meiotic progression during oogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000186 . obo:WBPhenotype_0000314 obo:IAO_0000115 "Animals are slight or meager in body size compared to control animals at the same developmental stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000314" ; a owl:Class ; rdfs:label "scrawny" ; rdfs:subClassOf obo:WBPhenotype_0000231 . obo:WBPhenotype_0000315 obo:IAO_0000115 "Any variation with respect to perception or response to mechanical stimuli compared to control animals." ; oboInOwl:hasAlternativeId "WBPhenotype:0000513" ; oboInOwl:hasBroadSynonym "Mec" ; oboInOwl:hasExactSynonym "touch response abnormal" ; oboInOwl:hasNarrowSynonym "mechanosensation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000315" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "mechanosensation variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, obo:WBPhenotype_0000738 . obo:WBPhenotype_0000316 obo:IAO_0000115 "Failure to execute a characteristic response when struck or stroked in the posterior region. In C. elegans, animals move forward movement when struck or stroked in the posterior region, usually with a hair or similar fiber. The posterior region lies between the vulva and the tail." ; oboInOwl:hasBroadSynonym "touch resistant posterior body" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "touch insensitive tail" ; oboInOwl:id "WBPhenotype:0000316" ; a owl:Class ; rdfs:label "touch resistant tail" ; rdfs:subClassOf obo:WBPhenotype_0000456 . obo:WBPhenotype_0000317 obo:IAO_0000115 "Animals are deficient in the foraging response in which an animal quickly pulls its head away from a stimulus to the nose (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000317" ; a owl:Class ; rdfs:label "head withdrawal defective" ; rdfs:subClassOf obo:WBPhenotype_0000315 . obo:WBPhenotype_0000318 obo:IAO_0000115 "Cells of the animals proceed through their replicative phase at a pace slower than observed for control cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000318" ; a owl:Class ; rdfs:label "cell cycle delayed" ; rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0001995, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007049 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007049 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000319 obo:IAO_0000115 "Animals have increased girth and increased length compared to control animals at the same developmental stage." ; oboInOwl:hasExactSynonym "body size enlarged" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000319" ; a owl:Class ; rdfs:label "large" ; rdfs:subClassOf obo:WBPhenotype_0000231, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000320 obo:IAO_0000115 "Animals show a decrease in survivorship after thawing compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000320" ; a owl:Class ; rdfs:label "reduced viability after freezing" ; rdfs:subClassOf obo:WBPhenotype_0000141 . obo:WBPhenotype_0000321 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control." ; oboInOwl:hasNarrowSynonym "nose morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000321" ; a owl:Class ; rdfs:label "nose morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008426 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008426 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000322 obo:IAO_0000115 "The extreme anterior part of the body appears blunted in shape." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000322" ; a owl:Class ; rdfs:label "nose rounded" ; rdfs:subClassOf obo:WBPhenotype_0000321 . obo:WBPhenotype_0000323 obo:IAO_0000115 "The most anterior portion of the animal appears bloated or distended." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000323" ; a owl:Class ; rdfs:label "head swollen" ; rdfs:subClassOf obo:WBPhenotype_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001851 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001851 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] ) ] ] . obo:WBPhenotype_0000324 obo:IAO_0000115 "Animals exhibit a decreased body length compared to control animals of the same developmental stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000324" ; a owl:Class ; rdfs:label "short" ; rdfs:subClassOf obo:WBPhenotype_0000229, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000574 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000574 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000325 obo:IAO_0000115 "Animals respond to arecoline at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000325" ; a owl:Class ; rdfs:label "arecoline hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001579, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_2814 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_2814 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000326 obo:IAO_0000115 "Animals fail to respond to the concentration of arecoline that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000326" ; a owl:Class ; rdfs:label "arecoline resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001578, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_2814 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_2814 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000327 obo:IAO_0000115 "Any defect in the muscle contractions of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000327" ; a owl:Class ; rdfs:label "corpus contraction defect" ; rdfs:subClassOf obo:WBPhenotype_0000747 . obo:WBPhenotype_0000328 obo:IAO_0000115 "Variations in the rhythmic contractions of the posterior pharynx (terminal bulb), such as timing, strength etc. In C. elegans contraction of the terminal bulb inverts the grinder, allowing bacteria in front of the grinder to be broken up and transported to the intestine." ; oboInOwl:hasNarrowSynonym "terminal bulb contraction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000328" ; a owl:Class ; rdfs:label "terminal bulb contraction variant" ; rdfs:subClassOf obo:WBPhenotype_0000980 . obo:WBPhenotype_0000329 obo:IAO_0000115 "The rhythmic contractions of pharyngeal compartments are no longer synchronized compared to control. In C. elegans the corpus and terminal bulb normally contract simultaneously." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000329" ; a owl:Class ; rdfs:label "pumping asynchronous" ; rdfs:subClassOf obo:WBPhenotype_0001006 . obo:WBPhenotype_0000330 obo:IAO_0000115 "Defects in rhythmic pharyngeal relaxations compared to control animals. In C. elegans pharyngeal relaxation follows a contraction event and facilitates bacterial trapping within the pharynx while expelling liquid." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000330" ; a owl:Class ; rdfs:label "pharyngeal relaxation defective" ; rdfs:subClassOf obo:WBPhenotype_0001004 . obo:WBPhenotype_0000331 obo:IAO_0000115 "Animals fail to respond to the concentration of sodium potassium ATPase antagonists that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasNarrowSynonym "ouabain resistant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000331" ; a owl:Class ; rdfs:label "inhibitors of na k atpase resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011 . obo:WBPhenotype_0000332 obo:IAO_0000115 "Animals respond to inhibitors of sodium potassium ATPase at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000332" ; a owl:Class ; rdfs:label "inhibitors of sodium potassium ATPase hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_63510 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_63510 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000333 obo:IAO_0000115 "The time interval of the stereotyped sequence of muscle contractions by individual pharyngeal muscles that act to draw food into the pharynx is shorter compared to that observed in control (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000333" ; a owl:Class ; rdfs:label "pharyngeal pumps brief" ; rdfs:subClassOf obo:WBPhenotype_0001006 . obo:WBPhenotype_0000334 obo:IAO_0000115 "Failure of muscle contractions in the corpus and isthmus to trap and transport bacteria posteriorly in the pharynx." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000334" ; a owl:Class ; rdfs:label "isthmus corpus slippery" ; rdfs:subClassOf obo:WBPhenotype_0000335 . obo:WBPhenotype_0000335 obo:IAO_0000115 "Failure of pharyngeal contractions to trap and transport bacteria posteriorly. In C. elegans this defect results in a distention of the pharyngeal lumen." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000335" ; a owl:Class ; rdfs:label "pharynx slippery" ; rdfs:subClassOf obo:WBPhenotype_0000634 . obo:WBPhenotype_0000336 obo:IAO_0000115 "Variations in the rhythmic relaxations of the posterior pharynx (terminal bulb). In C. elegans the relaxation of the terminal bulb returns the grinder to its relaxed forward position." ; oboInOwl:hasNarrowSynonym "terminal bulb relaxation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000336" ; a owl:Class ; rdfs:label "terminal bulb relaxation variant" ; rdfs:subClassOf obo:WBPhenotype_0000330 . obo:WBPhenotype_0000337 obo:IAO_0000115 "Failure of the grinder to come to a full relaxed position between pumps compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000337" ; a owl:Class ; rdfs:label "grinder relaxation defective" ; rdfs:subClassOf obo:WBPhenotype_0001480 . obo:WBPhenotype_0000338 obo:IAO_0000115 "Swelling in the post anal region compared to control. In C. elegans this swelling can be associated with infection from the nematode-specific bacterial pathogen, Microbacterium nematophilum." ; oboInOwl:hasBroadSynonym "Dar" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "deformed anal region" ; oboInOwl:id "WBPhenotype:0000338" ; a owl:Class ; rdfs:label "tail swelling" ; rdfs:subClassOf obo:WBPhenotype_0000073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001851 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001851 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] ) ] ] . obo:WBPhenotype_0000339 obo:IAO_0000115 "Worms sporatically appear turgid or swollen as a result of an excess number of eggs being retained in the uterus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000339" ; a owl:Class ; rdfs:label "transient bloating" ; rdfs:subClassOf obo:WBPhenotype_0000862 . obo:WBPhenotype_0000340 obo:IAO_0000115 "Animals fail to respond to the concentration of imipramine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000340" ; a owl:Class ; rdfs:label "imipramine resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, obo:WBPhenotype_0001598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_47499 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_47499 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000341 obo:IAO_0000115 "Animals respond to imipramine at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000341" ; a owl:Class ; rdfs:label "imipramine hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_47499 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_47499 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000342 obo:IAO_0000115 "Any variation in the form, structure or composition of the adult male tail including the lateral fan and rays compared to control." ; oboInOwl:hasNarrowSynonym "bursa morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000342" ; a owl:Class ; rdfs:label "bursa morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000070 . obo:WBPhenotype_0000343 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000908 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000343" ; a owl:Class ; rdfs:label "obsolete cloaca morphology abnormal" ; owl:deprecated true . obo:WBPhenotype_0000344 obo:IAO_0000115 "Any of the contents that comprise the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus extend into the external environment through the cloacal opening." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000344" ; a owl:Class ; rdfs:label "cloacal structures protrude" ; rdfs:subClassOf obo:WBPhenotype_0000908, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001598 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005774 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001598 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005774 ] ) ] ] . obo:WBPhenotype_0000345 obo:IAO_0000115 "Any variation that alters the physical partitioning and separation of a vulval precursor cell into daughter cells compared to control." ; oboInOwl:hasNarrowSynonym "VPC cell division abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000345" ; a owl:Class ; rdfs:label "VPC cell division variant" ; rdfs:subClassOf obo:WBPhenotype_0000746 . obo:WBPhenotype_0000346 obo:IAO_0000115 "Adult animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals." ; oboInOwl:hasNarrowSynonym "adult pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000346" ; a owl:Class ; rdfs:label "adult pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0001009 . obo:WBPhenotype_0000347 obo:IAO_0000115 "Any variation in the progression of the cuticle-lined sinus opening on the posterior ventral surface of the animal over time from its formation to its mature structure compared to control (Wormatlas). The function of the rectum is to excrete waste products from the alimentary system." ; oboInOwl:hasNarrowSynonym "rectal development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000347" ; a owl:Class ; rdfs:label "rectal development variant" ; rdfs:subClassOf obo:WBPhenotype_0000617, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005773 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005773 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000348 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0001735 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000348" ; a owl:Class ; rdfs:label "obsolete muscle activation defective" ; owl:deprecated true . obo:WBPhenotype_0000349 obo:IAO_0000115 "A semi-paralysed body phenotype in which muscle tone is lost and the animal fails to actively control its body shape (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "floppy", "limp" ; oboInOwl:id "WBPhenotype:0000349" ; a owl:Class ; rdfs:label "flaccid" ; rdfs:subClassOf obo:WBPhenotype_0000001 . obo:WBPhenotype_0000350 obo:IAO_0000115 "Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the hermaphrodite tail compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000350" ; a owl:Class ; rdfs:label "hermaphrodite tail spike variant" ; rdfs:subClassOf obo:WBPhenotype_0000968, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001340 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006979 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001340 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006979 ] ) ] ] . obo:WBPhenotype_0000351 obo:IAO_0000115 "Animals fail to emerge from an egg shell." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000351" ; a owl:Class ; rdfs:label "failure to hatch" ; rdfs:subClassOf obo:WBPhenotype_0000048, obo:WBPhenotype_0000050, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035188 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035188 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000352 obo:IAO_0000115 "Backward movement is not coordinated as in control. This often causes jerky or spastic backward locomotion." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000352" ; a owl:Class ; rdfs:label "backing uncoordinated" ; rdfs:subClassOf obo:WBPhenotype_0001005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000770 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043057 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000770 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043057 ] ) ] ] . obo:WBPhenotype_0000353 obo:IAO_0000115 "Animals spend more time backing compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000353" ; a owl:Class ; rdfs:label "backing increased" ; rdfs:subClassOf obo:WBPhenotype_0001005 . obo:WBPhenotype_0000354 obo:IAO_0000115 "Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues." ; oboInOwl:hasNarrowSynonym "cell differentiation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000354" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell differentiation variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030154 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030154 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000355 obo:IAO_0000115 "Specialization of HSN precursor cells to mature HSN neurons occurs at an earlier stage of development compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000355" ; a owl:Class ; rdfs:label "HSN differentiation precocious" ; rdfs:subClassOf obo:WBPhenotype_0000354, obo:WBPhenotype_0000439, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030154 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0006830 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030154 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0006830 ] ) ] ] . obo:WBPhenotype_0000356 obo:IAO_0000115 "The progression of immature germ cells to functional sperm is retarded compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000356" ; a owl:Class ; rdfs:label "spermatogenesis delayed" ; rdfs:subClassOf obo:WBPhenotype_0000670, obo:WBPhenotype_0000848, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000357 obo:IAO_0000115 "Animals lay inactivated oocytes. In C elegans this may be due to perturbations that eliminate spermatogenesis or result in the production of defective sperm." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000357" ; a owl:Class ; rdfs:label "unfertilized oocytes laid" ; rdfs:subClassOf obo:WBPhenotype_0000640 . obo:WBPhenotype_0000358 obo:IAO_0000115 "Animals execute supernumerary cell divisions post-hatching." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "supernumerary cell divisions" ; oboInOwl:id "WBPhenotype:0000358" ; a owl:Class ; rdfs:label "extra cell division postembryonic" ; rdfs:subClassOf obo:WBPhenotype_0000825 . obo:WBPhenotype_0000359 obo:IAO_0000115 "Animals exhibit variations in the response to the addition of tunicamycin compared to that observed in control animals. Tunicamycin induces the unfolded protein response." ; oboInOwl:hasNarrowSynonym "tunicamycin response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000359" ; a owl:Class ; rdfs:label "tunicamycin response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1904576 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1904576 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000360 obo:IAO_0000115 "The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell is impaired." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000360" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "cytoplasmic streaming defective" ; rdfs:subClassOf obo:WBPhenotype_0002612 . obo:WBPhenotype_0000361 obo:IAO_0000115 "Cessation of development at an intermediate stage in embryogenesis, immediately following the completion of gastrulation. In C. elegans this occurs around 350-390 minutes after first cleavage, cell number is at approximately 560 cells. At this time cell proliferation ceases and the embryo begins morphogenesis and elongation. The shape of the entire embryo within the eggshell resembles a lima bean (Wormatlas)." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "arrest during epiboly" ; oboInOwl:id "WBPhenotype:0000361" ; a owl:Class ; rdfs:label "lima bean arrest" ; rdfs:subClassOf obo:WBPhenotype_0000867 . obo:WBPhenotype_0000362 obo:IAO_0000115 "Any variation in the progression of the fluid-filled compartment inside the developing embryo at the onset of gastrulation over time from its formation to its mature structure compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "blastocoel abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000362" ; a owl:Class ; rdfs:label "blastocoel variant" ; rdfs:subClassOf obo:WBPhenotype_0000047 . obo:WBPhenotype_0000363 obo:IAO_0000115 "Any variation that delays the physical partitioning and separation of a cell into daughter cells compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000363" ; a owl:Class ; rdfs:label "cell division slow" ; rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0000746, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000364 obo:IAO_0000115 "The birefringent inclusions typically found in the intestinal cytoplasm accumulate extracellularly in the intestinal lumen." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000364" ; a owl:Class ; rdfs:label "gut granule birefringence misplaced" ; rdfs:subClassOf obo:WBPhenotype_0002240 . obo:WBPhenotype_0000365 obo:IAO_0000115 "Variations in the ability of an embryo to maintain osmotic balance. In C.elegans this can result in an embryo filling the egg shell and lysing." ; oboInOwl:hasBroadSynonym "Emb", "Eos" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000365" ; a owl:Class ; rdfs:label "embryo osmotic integrity defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001178 . obo:WBPhenotype_0000366 obo:IAO_0000115 "Cessation of development that normally occurs in C. elegans 520-620min after the first cleavage at 20C, the stage between the 2-fold and fully elongated embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "active elongation arrest" ; oboInOwl:id "WBPhenotype:0000366" ; a owl:Class ; rdfs:label "three fold arrest" ; rdfs:subClassOf obo:WBPhenotype_0000779 . obo:WBPhenotype_0000367 obo:IAO_0000115 "Cessation of development during the middle stage in embryogenesis of the worm in which the embryo is slightly folded within the eggshell (Wormatlas)." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "end of epiboly arrest" ; oboInOwl:id "WBPhenotype:0000367" ; a owl:Class ; rdfs:label "comma arrest emb" ; rdfs:subClassOf obo:WBPhenotype_0000864 . obo:WBPhenotype_0000368 obo:IAO_0000115 "Cessation of development that normally occurs in C. elegans 420-460 min after the first embryonic cleavage at 20C, the stage between the comma and 2-fold embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "arrest beginning elongation" ; oboInOwl:id "WBPhenotype:0000368" ; a owl:Class ; rdfs:label "one point five fold arrest emb" ; rdfs:subClassOf obo:WBPhenotype_0000864 . obo:WBPhenotype_0000369 obo:IAO_0000115 "Cessation of development during the final two stages in embryogenesis, 'early pretzel' stage and 'late pretzel' stage, just prior to hatching. The animal now is folded into four lengths within the eggshell and resembles a pretzel. By early pretzel stage, the head begins to move independently from the body (Wormatlas)." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "end of elongation arrest" ; oboInOwl:id "WBPhenotype:0000369" ; a owl:Class ; rdfs:label "pretzel arrest" ; rdfs:subClassOf obo:WBPhenotype_0000779 . obo:WBPhenotype_0000370 obo:IAO_0000115 "The fertilized oocytes have a greater than standard length measured end to end compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000370" ; a owl:Class ; rdfs:label "egg long" ; rdfs:subClassOf obo:WBPhenotype_0000373 . obo:WBPhenotype_0000371 obo:IAO_0000115 "The physical partitioning and separation of a cell into daughter cells is interupted." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000371" ; a owl:Class ; rdfs:label "cell division incomplete" ; rdfs:subClassOf obo:WBPhenotype_0000746, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] ) ] ] . obo:WBPhenotype_0000372 obo:IAO_0000115 "Animals lack the two small cells produced, each during one of the two meiotic cell divisions (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000372" ; a owl:Class ; rdfs:label "no polar body formation" ; rdfs:subClassOf obo:WBPhenotype_0000775, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008429 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008429 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000373 obo:IAO_0000115 "The overall structure or appearance of fertilized oocytes that are laid exhibit nonconsistent and significant deviation from that of control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000373" ; a owl:Class ; rdfs:label "egg shape variable" ; rdfs:subClassOf obo:WBPhenotype_0000037 . obo:WBPhenotype_0000374 obo:IAO_0000115 "The time interval in which early embryonic cell divisions occur is increased compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000374" ; a owl:Class ; rdfs:label "early divisions prolonged" ; rdfs:subClassOf obo:WBPhenotype_0000749 . obo:WBPhenotype_0000375 obo:IAO_0000115 "The time interval in which late embryonic cell divisions occur is increased compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000375" ; a owl:Class ; rdfs:label "later divisions prolonged" ; rdfs:subClassOf obo:WBPhenotype_0000749 . obo:WBPhenotype_0000376 obo:IAO_0000115 "Animals lack the inner space of the uterus through which the fertilized egg passes on its way out of the nematode via the vulva (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000376" ; a owl:Class ; rdfs:label "no uterine cavity" ; rdfs:subClassOf obo:WBPhenotype_0000289 . obo:WBPhenotype_0000377 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the internal space of the excretory canal compared to control animals." ; oboInOwl:hasNarrowSynonym "canal lumen morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000377" ; a owl:Class ; rdfs:label "canal lumen morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000704 . obo:WBPhenotype_0000378 obo:IAO_0000115 "Pharyngeal muscle contractions show less displacement than that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000378" ; a owl:Class ; rdfs:label "pharyngeal pumping shallow" ; rdfs:subClassOf obo:WBPhenotype_0000634, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001472 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001472 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] ) ] ] . obo:WBPhenotype_0000379 obo:IAO_0000115 "The most anterior portion of the animal contains a V-shaped indentation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000379" ; a owl:Class ; rdfs:label "head notched" ; rdfs:subClassOf obo:WBPhenotype_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001495 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001495 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] ) ] ] . obo:WBPhenotype_0000380 obo:IAO_0000115 "The final step of the defecation motor program does not occur at each cycle, but is activated occasionally. During this step in C. elegans specialized enteric muscles contract to expel the contents of the gut through the anus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000380" ; a owl:Class ; rdfs:label "expulsion infrequent" ; rdfs:subClassOf obo:WBPhenotype_0000996 . obo:WBPhenotype_0000381 obo:IAO_0000115 "Animals fail to respond to the concentration of serotonin reuptake inhibitors that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000381" ; a owl:Class ; rdfs:label "serotonin reuptake inhibitor resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_50949 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_50949 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000382 obo:IAO_0000115 "Animals respond to serotonin reuptake inhibitors at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000382" ; a owl:Class ; rdfs:label "serotonin reuptake inhibitor hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_50949 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_50949 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000383 obo:IAO_0000115 "The de novo synthesis of any lipid species is reduced compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lipid synthesis decreased" ; oboInOwl:id "WBPhenotype:0000383" ; a owl:Class ; rdfs:label "lipid synthesis defective" ; rdfs:subClassOf obo:WBPhenotype_0000725, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008610 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008610 ] ) ] ] . obo:WBPhenotype_0000384 obo:IAO_0000115 "Variations in the cue-directed extension of an axon towards a specific target site compared to control. (Axon guidance often depends on a combination of attractive and repulsive cues)." ; oboInOwl:hasNarrowSynonym "axon guidance abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "axon pathfinding abnormal" ; oboInOwl:id "WBPhenotype:0000384" ; a owl:Class ; rdfs:label "axon guidance variant" ; rdfs:subClassOf obo:WBPhenotype_0000944, obo:WBPhenotype_0001224, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007411 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007411 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000385 obo:IAO_0000115 "Animals produce an increased sperm population compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000385" ; a owl:Class ; rdfs:label "sperm excess" ; rdfs:subClassOf obo:WBPhenotype_0000670, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006798 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006798 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000386 obo:IAO_0000115 "Programmed cell death of germ cells caused by exposure to DNA-damaging chemical agents does not occur to the same extent as it does in control animals." ; oboInOwl:hasNarrowSynonym "genotoxic induced apoptosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "DNA damage induced apoptosis abnormal" ; oboInOwl:id "WBPhenotype:0000386" ; a owl:Class ; rdfs:label "genotoxic chemical induced apoptosis variant" ; rdfs:subClassOf obo:WBPhenotype_0002152 . obo:WBPhenotype_0000387 obo:IAO_0000115 "The mature male gametes lack self-propelled movement." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000387" ; a owl:Class ; rdfs:label "sperm nonmotile" ; rdfs:subClassOf obo:WBPhenotype_0000987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000300 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006798 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000300 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006798 ] ) ] ] . obo:WBPhenotype_0000388 obo:IAO_0000115 "Any variation in the form, structure or composition of the mature male gamete, which merges with an oocyte to create a fertilized embryo copared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "sperm morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000388" ; a owl:Class ; rdfs:label "sperm morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000900, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006798 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006798 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000389 obo:IAO_0000115 "Any perturbation that renders hermaphrodite derived sperm incompetent at fertilizing an oocyte." ; oboInOwl:hasBroadSynonym "Fer", "Spe" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000389" ; a owl:Class ; rdfs:label "hermaphrodite sperm fertilization defective" ; rdfs:subClassOf obo:WBPhenotype_0000694, obo:WBPhenotype_0002440 . obo:WBPhenotype_0000390 obo:IAO_0000115 "Spermatids fail to mature into active sperm. In C. elegans round sessile spermatids mature into spermatozoa (polarized cells with a motile pseudopod), upon copulation or treatment with proteases." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "spermiogenesis defective" ; oboInOwl:id "WBPhenotype:0000390" ; a owl:Class ; rdfs:label "spermatid activation defective" ; rdfs:subClassOf obo:WBPhenotype_0000670 . obo:WBPhenotype_0000391 obo:IAO_0000115 "Animals lack one or more of the stereotyped muscle contractions that result in defecation compared to control. In C. elegans these contractions include posterior body contraction (pBoc), anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000391" ; a owl:Class ; rdfs:label "defecation missing motor steps" ; rdfs:subClassOf obo:WBPhenotype_0000650 . obo:WBPhenotype_0000392 obo:IAO_0000115 "Animals exhibit an increase in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000392" ; a owl:Class ; rdfs:label "intestinal fluorescence increased" ; rdfs:subClassOf obo:WBPhenotype_0000293, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001926 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001926 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] ) ] ] . obo:WBPhenotype_0000393 obo:IAO_0000115 "Characteristic movement of cells from one site to another is abolished compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000393" ; a owl:Class ; rdfs:label "cell migration failure" ; rdfs:subClassOf obo:WBPhenotype_0000594, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016477 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016477 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000394 obo:IAO_0000115 "Any variation in the movement of a protein through a gel matrix when an electric field is applied compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000394" ; a owl:Class ; rdfs:label "electrophoretic variant protein" ; rdfs:subClassOf obo:WBPhenotype_0000112 . obo:WBPhenotype_0000395 obo:IAO_0000115 "Animals are agametic (lack mature germ cells)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000395" ; a owl:Class ; rdfs:label "no differentiated gametes" ; rdfs:subClassOf obo:WBPhenotype_0000894, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CL_0000300 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CL_0000300 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000396 obo:IAO_0000115 "Gonadal arms do not bend or curve. In C. elegans gonad arms normally reflex to form a stereotypical U-shaped pattern." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000396" ; a owl:Class ; rdfs:label "non reflexed gonad arms" ; rdfs:subClassOf obo:WBPhenotype_0000399 . obo:WBPhenotype_0000397 obo:IAO_0000115 "Animals do not respond to prodding with a fine platinum wire or similar tool compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "harsh body touch insensitive" ; oboInOwl:id "WBPhenotype:0000397" ; a owl:Class ; rdfs:label "harsh body touch resistant" ; rdfs:subClassOf obo:WBPhenotype_0000456 . obo:WBPhenotype_0000398 obo:IAO_0000115 "Animals do not respond to stroking to the head or tail with a hair or similar fiber, but does respond to stronger mechanical stimuli such as prodding with a fine platinum wire or similar tool compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "light body touch insensitive" ; oboInOwl:id "WBPhenotype:0000398" ; a owl:Class ; rdfs:label "light body touch resistant" ; rdfs:subClassOf obo:WBPhenotype_0000456 . obo:WBPhenotype_0000399 obo:IAO_0000115 "Any variation in the progression of the components of the gonad that are separate from the germline proper over time from its formation to its mature structure compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "somatic gonad development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000399" ; a owl:Class ; rdfs:label "somatic gonad development variant" ; rdfs:subClassOf obo:WBPhenotype_0000691, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005785 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005785 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000400 obo:IAO_0000115 "The developmental progression of the set of precursor cells that later give rise to the somatic tissues of the gonadal tract is impaired (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000400" ; a owl:Class ; rdfs:label "somatic gonad primordium development defective" ; rdfs:subClassOf obo:WBPhenotype_0000399 . obo:WBPhenotype_0000401 obo:IAO_0000115 "Animals lack the portion of the somatic gonad which encloses the fertilized eggs after their passage through the spermatheca (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000401" ; a owl:Class ; rdfs:label "no uterus" ; rdfs:subClassOf obo:WBPhenotype_0000624, obo:WBPhenotype_0002556, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006760 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006760 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000402 obo:IAO_0000115 "Lawn avoidance refers to behavior in which animals initially enter the bacterial lawn but later exit and remain near the edge of the bacteria. Lawn avoidance is often a response to bacterial food, that is pathogenic or low quality to the animal." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000402" ; a owl:Class ; rdfs:label "avoids bacterial lawn" ; rdfs:subClassOf obo:WBPhenotype_0000659, obo:WBPhenotype_0002545 . obo:WBPhenotype_0000403 obo:IAO_0000115 "Any defect in the movement of sperm out of the seminal vesicle and into the vas deferens following tonic insertion of spicules into the mating partner compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000403" ; a owl:Class ; rdfs:label "sperm transfer initiation defective" ; rdfs:subClassOf obo:WBPhenotype_0000284 . obo:WBPhenotype_0000404 obo:IAO_0000115 "The emergence of larvae from their protective egg shells is retarded compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000404" ; a owl:Class ; rdfs:label "delayed hatching" ; rdfs:subClassOf obo:WBPhenotype_0000048, obo:WBPhenotype_0000438, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035188 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035188 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000405 obo:IAO_0000115 "The size of haploid female germ cells (oocytes) are significantly larger compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "oocytes large" ; oboInOwl:id "WBPhenotype:0000405" ; a owl:Class ; rdfs:label "giant oocytes" ; rdfs:subClassOf obo:WBPhenotype_0001260, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006797 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006797 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000406 obo:IAO_0000115 "Animals have protrusions or bumps on their exterior which are not characteristic of control animals." ; oboInOwl:hasBroadSynonym "Lpy" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000406" ; a owl:Class ; rdfs:label "lumpy" ; rdfs:subClassOf obo:WBPhenotype_0000535 . obo:WBPhenotype_0000407 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0001509 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000407" ; a owl:Class ; rdfs:label "obsolete ray loss" ; owl:deprecated true . obo:WBPhenotype_0000408 obo:IAO_0000115 "The process through which a dauer larva reverts to normal developmental programs is blocked." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000408" ; a owl:Class ; rdfs:label "dauer recovery inhibited" ; rdfs:subClassOf obo:WBPhenotype_0000127 . obo:WBPhenotype_0000409 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any of its parts at different stages of the lifecycle, compared to control animals." ; oboInOwl:hasBroadSynonym "Vab" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000409" ; a owl:Class ; rdfs:label "organism morphology variable" ; rdfs:subClassOf obo:WBPhenotype_0000535, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:PATO_0001227 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:PATO_0001227 ] ) ] ] . obo:WBPhenotype_0000410 obo:IAO_0000115 "Animals lack the stereotyped sequence of muscle contractions that result in defecation over a fixed time period compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000410" ; a owl:Class ; rdfs:label "no defecation cycle" ; rdfs:subClassOf obo:WBPhenotype_0000207, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035882 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035882 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000411 obo:IAO_0000115 "Animals die as rigid, rod-like larva. In C. elegans this defect is often caused by the misspecification of the excretory duct cell." ; oboInOwl:hasBroadSynonym "Lvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Let" ; oboInOwl:id "WBPhenotype:0000411" ; a owl:Class ; rdfs:label "rod like larval lethal" ; rdfs:subClassOf obo:WBPhenotype_0000035, obo:WBPhenotype_0000054, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:PATO_0001873 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom obo:PATO_0001873 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] . obo:WBPhenotype_0000412 obo:IAO_0000115 "Failure to execute the characteristic response to 1-octanol as defined by control animals. In C.elegans 1-octanol is typically a repellant." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000412" ; a owl:Class ; rdfs:label "octanol chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001448, obo:WBPhenotype_0001452, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050919 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_37868 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050919 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_37868 ] ) ] ] . obo:WBPhenotype_0000413 obo:IAO_0000115 "Pharyngeal muscle is immobilized resulting in lack of pumping or lack of response to external stimulation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000413" ; a owl:Class ; rdfs:label "pharyngeal muscle paralyzed" ; rdfs:subClassOf obo:WBPhenotype_0000980 . obo:WBPhenotype_0000414 obo:IAO_0000115 "The cell takes on a different identity from which it was initially committed." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000414" ; a owl:Class ; rdfs:label "cell fate transformation" ; rdfs:subClassOf obo:WBPhenotype_0000216 . obo:WBPhenotype_0000415 obo:IAO_0000115 "Animals exhibit variations in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control." ; oboInOwl:hasNarrowSynonym "necrotic cell death abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000415" ; a owl:Class ; rdfs:label "necrotic cell death variant" ; rdfs:subClassOf obo:WBPhenotype_0000729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0070265 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0070265 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000416 obo:IAO_0000115 "Variations in the generation of the nutrient protein produced by intestinal cells and secreted by them into the pseudocoelom, from which it can be shared with other tissues in the body compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "yolk synthesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "vitellogenin synthesis abnormal" ; oboInOwl:id "WBPhenotype:0000416" ; a owl:Class ; rdfs:label "yolk synthesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001093, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007296 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007296 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000417 obo:IAO_0000115 "The process of physical partitioning and separation of a cell into daughter cells is abolished." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000417" ; a owl:Class ; rdfs:label "cell division failure" ; rdfs:subClassOf obo:WBPhenotype_0000746, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000418 obo:IAO_0000115 "The physical partitioning and separation of an intestinal cell into daughter cells is abolished." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000418" ; a owl:Class ; rdfs:label "intestinal cell division failure" ; rdfs:subClassOf obo:WBPhenotype_0000417 . obo:WBPhenotype_0000419 obo:IAO_0000115 "Animals die at the L3 stage of the life cycle." ; oboInOwl:hasBroadSynonym "Let", "Lvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000419" ; a owl:Class ; rdfs:label "L3 lethal" ; rdfs:subClassOf obo:WBPhenotype_0000058, obo:WBPhenotype_0000116, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000035 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000035 ] ) ] ] . obo:WBPhenotype_0000420 obo:IAO_0000115 "Animals respond to levamisole at a lower concentration or a shorter exposure compared to control animals. Levamisole is a cholinergic agonist." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "tetramisole hypersensitive" ; oboInOwl:id "WBPhenotype:0000420" ; a owl:Class ; rdfs:label "levamisole hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000845, obo:WBPhenotype_0001579, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6432 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6432 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000421 obo:IAO_0000115 "Animals fail to respond to the concentration of levamisole that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans resistance to levamisole is often assayed via body contraction response, ventral tail curling response etc." ; oboInOwl:hasBroadSynonym "Lev R" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "tetramisole resistant" ; oboInOwl:id "WBPhenotype:0000421" ; a owl:Class ; rdfs:label "levamisole resistant" ; rdfs:subClassOf obo:WBPhenotype_0000845, obo:WBPhenotype_0001502, obo:WBPhenotype_0001578, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6432 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6432 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000422 obo:IAO_0000115 "Animals exhibit spasmodic muscle twitching superimposed on normal sinusoidal motion." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000422" ; a owl:Class ; rdfs:label "twitcher" ; rdfs:subClassOf obo:WBPhenotype_0001701 . obo:WBPhenotype_0000423 obo:IAO_0000115 "Any variation in the contractions of the muscles in the most anterior body region of the animal compared to control." ; oboInOwl:hasNarrowSynonym "head muscle contraction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000423" ; a owl:Class ; rdfs:label "head muscle contraction variant" ; rdfs:subClassOf obo:WBPhenotype_0000611 . obo:WBPhenotype_0000424 obo:IAO_0000115 "Any variation in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." ; oboInOwl:hasNarrowSynonym "antibody staining abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000424" ; a owl:Class ; rdfs:label "antibody staining variant" ; rdfs:subClassOf obo:WBPhenotype_0000112 . obo:WBPhenotype_0000425 obo:IAO_0000115 "Any variation that results in a decrease in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000425" ; a owl:Class ; rdfs:label "antibody staining reduced" ; rdfs:subClassOf obo:WBPhenotype_0000424 . obo:WBPhenotype_0000426 obo:IAO_0000115 "Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000426" ; a owl:Class ; rdfs:label "antibody staining increased" ; rdfs:subClassOf obo:WBPhenotype_0000424 . obo:WBPhenotype_0000427 obo:IAO_0000115 "Animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000427" ; a owl:Class ; rdfs:label "no cuticle" ; rdfs:subClassOf obo:WBPhenotype_0000201, obo:WBPhenotype_0002558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000428 obo:IAO_0000115 "Adult animals lack the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000428" ; a owl:Class ; rdfs:label "no adult cuticle" ; rdfs:subClassOf obo:WBPhenotype_0000427, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] . obo:WBPhenotype_0000429 obo:IAO_0000115 "Any variation in the progression of the specialized structures of the animal which allow the successful transfer of sperm from one organism to another, compared to control." ; oboInOwl:hasNarrowSynonym "copulatory structure development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000429" ; a owl:Class ; rdfs:label "copulatory structure development variant" ; rdfs:subClassOf obo:WBPhenotype_0000624 . obo:WBPhenotype_0000430 obo:IAO_0000115 "Any variation in the progression of the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm over time from its formation to its mature structure compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "male copulatory structure development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000430" ; a owl:Class ; rdfs:label "male copulatory structure development variant" ; rdfs:subClassOf obo:WBPhenotype_0000429 . obo:WBPhenotype_0000431 obo:IAO_0000115 "Any variation in the progression of the specialized structures of a hermaphrodite which allow the successful transfer of sperm from a male, compared to control." ; oboInOwl:hasNarrowSynonym "hermaphrodite copulatory structure development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000431" ; a owl:Class ; rdfs:label "hermaphrodite copulatory structure development variant" ; rdfs:subClassOf obo:WBPhenotype_0000429 . obo:WBPhenotype_0000432 obo:IAO_0000115 "Animals lack the specialized structures of the male tail which allow the animal to sense the presence of the hermaphrodite, search her body for the vulval opening, grasp onto the vulva, and to transfer sperm (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000432" ; a owl:Class ; rdfs:label "male copulatory structure absent" ; rdfs:subClassOf obo:WBPhenotype_0000430 . obo:WBPhenotype_0000433 obo:IAO_0000115 "Variations in the processes involving the production of new DNA strands compared to control." ; oboInOwl:hasNarrowSynonym "DNA synthesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000433" ; a owl:Class ; rdfs:label "DNA synthesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006260 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006260 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000434 obo:IAO_0000115 "The developmental process by which a progressive change in the state of some part of an organism specifically contributing to its ability to form offspring is impaired." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000434" ; a owl:Class ; rdfs:label "sexual maturation defective" ; rdfs:subClassOf obo:WBPhenotype_0000624 . obo:WBPhenotype_0000435 obo:IAO_0000115 "OBSOLETE. Any change in the subcellular localization of a protein." ; obo:IAO_0100001 obo:WBPhenotype_0000436 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000435" ; a owl:Class ; rdfs:label "obsolete protein localization abnormal" ; owl:deprecated true . obo:WBPhenotype_0000436 obo:IAO_0000115 "Any variation in the placement of a protein within in a cell or cellular compartment compared to control." ; oboInOwl:hasAlternativeId "WBPhenotype:0000435" ; oboInOwl:hasExactSynonym "protein localization abnormal" ; oboInOwl:hasNarrowSynonym "protein subcellular localization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000436" ; a owl:Class ; rdfs:label "protein subcellular localization variant" ; rdfs:subClassOf obo:WBPhenotype_0001408, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034613 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034613 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000437 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000033 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000437" ; a owl:Class ; rdfs:label "obsolete heterochronic defect" ; owl:deprecated true . obo:WBPhenotype_0000438 obo:IAO_0000115 "Variations that result in the deceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000438" ; a owl:Class ; rdfs:label "retarded heterochronic variations" ; rdfs:subClassOf obo:WBPhenotype_0000033 . obo:WBPhenotype_0000439 obo:IAO_0000115 "Variations that result in the acceleration of the rate, frequency or extent of the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000439" ; a owl:Class ; rdfs:label "precocious heterochronic variations" ; rdfs:subClassOf obo:WBPhenotype_0000033 . obo:WBPhenotype_0000440 obo:IAO_0000115 "The structure made by the processes of the excretory canal cell is increased in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "long excretory canals" ; oboInOwl:id "WBPhenotype:0000440" ; a owl:Class ; rdfs:label "excretory canals long" ; rdfs:subClassOf obo:WBPhenotype_0000704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000573 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005775 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000573 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005775 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000441 obo:IAO_0000115 "Tails change shape and undergo retraction thereby forming a 'peloderan' or 'rounded' adult tail." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000441" ; a owl:Class ; rdfs:label "tail rounded" ; rdfs:subClassOf obo:WBPhenotype_0000073, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000411 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000411 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000442 obo:IAO_0000115 "The developmental progression of a larva over time, from its formation to its mature structure is delayed compared to control. The larva is the early, immature form of an animal between hatching and adulthood." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000442" ; a owl:Class ; rdfs:label "larval development retarded" ; rdfs:subClassOf obo:WBPhenotype_0000750, obo:WBPhenotype_0000848, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000443 obo:IAO_0000115 "Any variation in the appearance of the elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control." ; oboInOwl:hasNarrowSynonym "spicule morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000443" ; a owl:Class ; rdfs:label "spicule morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005312 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005312 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000444 obo:IAO_0000115 "The length of the adult male tail, including the lateral fan and rays, is extended compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000444" ; a owl:Class ; rdfs:label "bursa elongated" ; rdfs:subClassOf obo:WBPhenotype_0000342 . obo:WBPhenotype_0000445 obo:IAO_0000115 "Males generate yolk, the nutrient protein, normally produced and secreted by hermaphrodite or female intestinal cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "vitellogenin synthesis in males" ; oboInOwl:id "WBPhenotype:0000445" ; a owl:Class ; rdfs:label "yolk synthesis in males" ; rdfs:subClassOf obo:WBPhenotype_0000416 . obo:WBPhenotype_0000446 obo:IAO_0000115 "Animals execute extra larval molts compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000446" ; a owl:Class ; rdfs:label "supernumerary molt" ; rdfs:subClassOf obo:WBPhenotype_0002041 . obo:WBPhenotype_0000447 obo:IAO_0000115 "Variations in the progression of an animal over time from the end of larval stage to a mature adult compared to control animals." ; oboInOwl:hasNarrowSynonym "adult development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000447" ; a owl:Class ; rdfs:label "adult development variant" ; rdfs:subClassOf obo:WBPhenotype_0000049 . obo:WBPhenotype_0000448 obo:IAO_0000115 "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) over time in adults compared to control animals (Wormatlas)." ; oboInOwl:hasNarrowSynonym "adult cuticle development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000448" ; a owl:Class ; rdfs:label "adult cuticle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000447 . obo:WBPhenotype_0000449 obo:IAO_0000115 "A duplication of the developmental program that forms the adult-type rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000449" ; a owl:Class ; rdfs:label "second adult cuticle" ; rdfs:subClassOf obo:WBPhenotype_0000448 . obo:WBPhenotype_0000450 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000506 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000450" ; a owl:Class ; rdfs:label "obsolete swollen male tail" ; owl:deprecated true . obo:WBPhenotype_0000451 obo:IAO_0000115 "Any irregular swelling in discrete regions of the head." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000451" ; a owl:Class ; rdfs:label "head protrusion" ; rdfs:subClassOf obo:WBPhenotype_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001598 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001598 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] ) ] ] . obo:WBPhenotype_0000452 obo:IAO_0000115 "Any irregular swelling in discrete regions of the tail, usually caused by a local defect in the normal smooth tapering of the hypodermis and/or cuticle (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000452" ; a owl:Class ; rdfs:label "tail protrusions" ; rdfs:subClassOf obo:WBPhenotype_0000073 . obo:WBPhenotype_0000453 obo:IAO_0000115 "Any irregular swelling in discrete regions of the body region between the head and the tail." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000453" ; a owl:Class ; rdfs:label "body protrusions" ; rdfs:subClassOf obo:WBPhenotype_0000072 . obo:WBPhenotype_0000454 obo:IAO_0000115 "The anterior end (which typically includes the anterior sensilla, pharynx and all muscles that are innervated by the nerve ring)of the body appears distorted, usually due to uncharacteristic winding." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000454" ; a owl:Class ; rdfs:label "head twisted" ; rdfs:subClassOf obo:WBPhenotype_0000071 . obo:WBPhenotype_0000455 obo:IAO_0000115 "Animals exhibit abrupt transitions while traveling from one location to another." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000455" ; a owl:Class ; rdfs:label "jerky movement" ; rdfs:subClassOf obo:WBPhenotype_0001701 . obo:WBPhenotype_0000456 obo:IAO_0000115 "Variations in characteristic response with respect to perception or transmission of a touch stimulus compared to responses in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "touch insensitive" ; oboInOwl:id "WBPhenotype:0000456" ; a owl:Class ; rdfs:label "touch resistant" ; rdfs:subClassOf obo:WBPhenotype_0000315 . obo:WBPhenotype_0000457 obo:IAO_0000115 "Animals show enhanced suceptibility to deprivation of nourishment, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000457" ; a owl:Class ; rdfs:label "organism starvation hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000147 . obo:WBPhenotype_0000458 obo:IAO_0000115 "Animals show enhanced tolerance to deprivation of nourishment, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000458" ; a owl:Class ; rdfs:label "starvation resistant" ; rdfs:subClassOf obo:WBPhenotype_0000147 . obo:WBPhenotype_0000459 obo:IAO_0000115 "Animals exhibit variations in their response to any chemical substance that is used for killing pests, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "pesticide response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000459" ; a owl:Class ; rdfs:label "pesticide response variant" ; rdfs:subClassOf obo:WBPhenotype_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_25944 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_25944 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000460 obo:IAO_0000115 "Animals exhibit variations in their response to paraquat compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "paraquat response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "methyl viologen response abnormal" ; oboInOwl:id "WBPhenotype:0000460" ; a owl:Class ; rdfs:label "paraquat response variant" ; rdfs:subClassOf obo:WBPhenotype_0000459, obo:WBPhenotype_0000523, obo:WBPhenotype_0001620, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1901562 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1901562 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000461 obo:IAO_0000115 "Animals fail to respond to the concentration of paraquat that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000461" ; a owl:Class ; rdfs:label "paraquat resistant" ; rdfs:subClassOf obo:WBPhenotype_0000460, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_34905 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_34905 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000462 obo:IAO_0000115 "Animals respond to paraquat at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasBroadSynonym "reactive oxygen species hypersensitive" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000462" ; a owl:Class ; rdfs:label "paraquat hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000460, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_34905 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_34905 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000463 obo:IAO_0000115 "Animals exhibit variations in processes that are responsible for chemical changes compared to control animals. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation." ; oboInOwl:hasNarrowSynonym "metabolic pathway abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000463" ; a owl:Class ; rdfs:label "metabolic pathway variant" ; rdfs:subClassOf obo:WBPhenotype_0000027 . obo:WBPhenotype_0000464 obo:IAO_0000115 "Animals exhibit variations in their response to oxygen compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "oxygen response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000464" ; a owl:Class ; rdfs:label "oxygen response variant" ; rdfs:subClassOf obo:WBPhenotype_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_25805 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_25805 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000465 obo:IAO_0000115 "Animals fail to respond to the high concentrations of oxygen that elicit a response in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000465" ; a owl:Class ; rdfs:label "high oxygen resistant" ; rdfs:subClassOf obo:WBPhenotype_0000464 . obo:WBPhenotype_0000466 obo:IAO_0000115 "Animals respond to hyperoxic (high oxygen tension) conditions after a shorter exposure time compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000466" ; a owl:Class ; rdfs:label "high oxygen hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000464 . obo:WBPhenotype_0000467 obo:IAO_0000115 "Animals exhibit an increase in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000467" ; a owl:Class ; rdfs:label "age associated fluorescence increased" ; rdfs:subClassOf obo:WBPhenotype_0001009 . obo:WBPhenotype_0000468 obo:IAO_0000115 "Animals exhibit a decrease in the intensity of fluorescence signals in intestinal cells with advancing age, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000468" ; a owl:Class ; rdfs:label "age associated fluorescence reduced" ; rdfs:subClassOf obo:WBPhenotype_0001009 . obo:WBPhenotype_0000469 obo:IAO_0000115 "The daughters of the Q neuroblasts exhibit variation in their characteristic movements compared to control animals." ; oboInOwl:hasNarrowSynonym "Q neuroblast lineage migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000469" ; a owl:Class ; rdfs:label "Q neuroblast lineage migration variant" ; rdfs:subClassOf obo:WBPhenotype_0001140 . obo:WBPhenotype_0000470 obo:IAO_0000115 "Any variation in the normal anterior movement of the HSN motor neurons from their birthplace in the tail to positions near the middle of the embryo compared to control animals." ; oboInOwl:hasNarrowSynonym "HSN migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000470" ; a owl:Class ; rdfs:label "HSN migration variant" ; rdfs:subClassOf obo:WBPhenotype_0001229 . obo:WBPhenotype_0000471 obo:IAO_0000115 "Any variation in the normal posterior movement of the ALM mechanosensory neurons from their birthplace (anterior to the V1 hypodermal cell) to positions in between the V2 and V3 cells in the embryo compared to control animals." ; oboInOwl:hasNarrowSynonym "ALM migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000471" ; a owl:Class ; rdfs:label "ALM migration variant" ; rdfs:subClassOf obo:WBPhenotype_0001520 . obo:WBPhenotype_0000472 obo:IAO_0000115 "Animals lack the early blast cells that give rise to the gut tissue (Wormatlas)." ; oboInOwl:hasExactSynonym "gutless" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000472" ; a owl:Class ; rdfs:label "endoderm absent" ; rdfs:subClassOf obo:WBPhenotype_0000749 . obo:WBPhenotype_0000473 obo:IAO_0000115 "Animals become increasingly sluggish/immobilized as they age." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000473" ; a owl:Class ; rdfs:label "progressive paralysis" ; rdfs:subClassOf obo:WBPhenotype_0000644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000763 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:PATO_0001818 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000763 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:PATO_0001818 ] ) ] ] . obo:WBPhenotype_0000474 obo:IAO_0000115 "Any variation in the connection of the cell(s) whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control." ; oboInOwl:hasBroadSynonym "Mua" ; oboInOwl:hasNarrowSynonym "muscle attachment abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000474" ; a owl:Class ; rdfs:label "muscle attachment variant" ; rdfs:subClassOf obo:WBPhenotype_0000622, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016203 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016203 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000475 obo:IAO_0000115 "Animals fail to establish or maintain the connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000475" ; a owl:Class ; rdfs:label "muscle detached" ; rdfs:subClassOf obo:WBPhenotype_0000474, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0003675 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0003675 ] ) ] ] . obo:WBPhenotype_0000476 obo:IAO_0000115 "The connection between cell(s) whose principal function is to provide contractile forces and its neighboring cells or tissues diminishes over time." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000476" ; a owl:Class ; rdfs:label "progressive muscle detachment" ; rdfs:subClassOf obo:WBPhenotype_0000475, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:PATO_0001818 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:PATO_0001818 ] ) ] ] . obo:WBPhenotype_0000477 obo:IAO_0000115 "Any variation in the change in direction of a wave of light after passage through the nucleolus compared to control. The nucleolus is a small dense body in the nucleus." ; oboInOwl:hasNarrowSynonym "nucleolus refraction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000477" ; a owl:Class ; rdfs:label "nucleolus refraction variant" ; rdfs:subClassOf obo:WBPhenotype_0000722 . obo:WBPhenotype_0000478 obo:IAO_0000115 "Variations in the ability of an animal to remain within a defined temperature. In C. elegans, animals tend to track and stay within a temperature that is most closely related to their cultivation temperature." ; oboInOwl:hasNarrowSynonym "isothermal tracking behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "thermotaxis abnormal" ; oboInOwl:id "WBPhenotype:0000478" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "isothermal tracking behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0002513 . obo:WBPhenotype_0000479 obo:IAO_0000115 "Eggs show deficiencies in chroma resulting in increased translucency." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000479" ; a owl:Class ; rdfs:label "egg pale" ; rdfs:subClassOf obo:WBPhenotype_0000970, obo:WBPhenotype_0001261 . obo:WBPhenotype_0000480 obo:IAO_0000115 "Failure to execute the characteristic response to pyrazine as defined by control animals. In C. elegans pyrazine is typically an attractant." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000480" ; a owl:Class ; rdfs:label "pyrazine chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001474, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_30953 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_30953 ] ) ] ] . obo:WBPhenotype_0000481 obo:IAO_0000115 "Any variation in the directed movement of an animal in response to chemical repellants as defined by control animals." ; oboInOwl:hasNarrowSynonym "negative chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "chemical avoidance abnormal", "chemoaversion abnormal" ; oboInOwl:id "WBPhenotype:0000481" ; a owl:Class ; rdfs:label "negative chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001434, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050919 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050919 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000482 obo:IAO_0000115 "Failure to execute the characteristic response to garlic as defined by control animals. In C. elegans, garlic is typically a repellent." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000482" ; a owl:Class ; rdfs:label "garlic chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001449, obo:WBPhenotype_0001451 . obo:WBPhenotype_0000483 obo:IAO_0000115 "Animals lack the different inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000483" ; a owl:Class ; rdfs:label "no gut granules" ; rdfs:subClassOf obo:WBPhenotype_0000103 . obo:WBPhenotype_0000484 obo:IAO_0000115 "The organism's size during the embryonic developmental stage is decreased compared to that observed in control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000484" ; a owl:Class ; rdfs:label "embryo small" ; rdfs:subClassOf obo:WBPhenotype_0001136, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000003 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000003 ] ) ] ] . obo:WBPhenotype_0000485 obo:IAO_0000115 "The survival of animals in the alternative larval stage which they enter when placed under conditions of environmental stress is reduced." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "reduced dauer survival" ; oboInOwl:id "WBPhenotype:0000485" ; a owl:Class ; rdfs:label "dauer death increased" ; rdfs:subClassOf obo:WBPhenotype_0002527 . obo:WBPhenotype_0000486 obo:IAO_0000115 "Animals respond to colchicine at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000486" ; a owl:Class ; rdfs:label "colchicine hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_23359 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_23359 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000487 obo:IAO_0000115 "Animals fail to respond to the concentration of colchicine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000487" ; a owl:Class ; rdfs:label "colchicine resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_23359 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_23359 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000488 obo:IAO_0000115 "Animals respond to chloroquine at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000488" ; a owl:Class ; rdfs:label "chloroquine hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_3638 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_3638 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000489 obo:IAO_0000115 "Animals fail to respond to the concentration of chloroquine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000489" ; a owl:Class ; rdfs:label "chloroquine resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_3638 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_3638 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000490 obo:IAO_0000115 "The components of the feeding organ fail to be arranged in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000490" ; a owl:Class ; rdfs:label "pharynx disorganized" ; rdfs:subClassOf obo:WBPhenotype_0000707, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000937 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000937 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] . obo:WBPhenotype_0000491 obo:IAO_0000115 "Any observed morphological defects of the isthmus." ; oboInOwl:hasNarrowSynonym "isthmus morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "isthmus malformed" ; oboInOwl:id "WBPhenotype:0000491" ; a owl:Class ; rdfs:label "isthmus morphology defective" ; rdfs:subClassOf obo:WBPhenotype_0000709, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003734 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003734 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000492 obo:IAO_0000115 "Any variation in the form, structure or composition of the extended anterior region of the pharynx lying just anterior to the isthmus and terminal bulb compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "corpus morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "corpus malformed" ; oboInOwl:id "WBPhenotype:0000492" ; a owl:Class ; rdfs:label "corpus morphology defective" ; rdfs:subClassOf obo:WBPhenotype_0000709, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003733 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003733 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000493 obo:IAO_0000115 "Any variation in the form, structure or composition of the first pharyngeal bulb compared to control." ; oboInOwl:hasNarrowSynonym "metacorpus morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "metacarpas malformed" ; oboInOwl:id "WBPhenotype:0000493" ; a owl:Class ; rdfs:label "metacorpus morphology defective" ; rdfs:subClassOf obo:WBPhenotype_0000709, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003711 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003711 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000494 obo:IAO_0000115 "Cessation of development that normally occurs in C. elegans 460-520 min after the first cleavage at 20C, the stage between the 1.5-fold and 3-fold embryo." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000494" ; a owl:Class ; rdfs:label "two fold arrest" ; rdfs:subClassOf obo:WBPhenotype_0000779 . obo:WBPhenotype_0000495 obo:IAO_0000115 "Animals have finger-like sensory sensilla (rays) that are present in places they are normally not found, when compared to the location in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000495" ; a owl:Class ; rdfs:label "ray ectopic" ; rdfs:subClassOf obo:WBPhenotype_0000199, obo:WBPhenotype_0002498, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000628 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000628 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000496 obo:IAO_0000115 "Males lack the specialized sensory papillae that lie along the posterior half of the body." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000496" ; a owl:Class ; rdfs:label "male postdeirid sensilla absent" ; rdfs:subClassOf obo:WBPhenotype_0001008 . obo:WBPhenotype_0000497 obo:IAO_0000115 "Animals exhibit variations in their response to gamma ray radiation compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "organism gamma ray response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000497" ; a owl:Class ; rdfs:label "organism gamma ray response variant" ; rdfs:subClassOf obo:WBPhenotype_0000686, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010332 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010332 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000498 obo:IAO_0000115 "Animals exhibit variations in their response to methyl methanesulfonate compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "methyl methanesulfonate response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "MMS response abnormal" ; oboInOwl:id "WBPhenotype:0000498" ; a owl:Class ; rdfs:label "methyl methanesulfonate response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_25255 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_25255 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000499 obo:IAO_0000115 "Animals exhibit variations in their response to ethyl methanesulfonate (EMS) compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "ethyl methanesulfonate response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "EMS response abnormal" ; oboInOwl:id "WBPhenotype:0000499" ; a owl:Class ; rdfs:label "ethyl methanesulfonate response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_23994 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_23994 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000500 obo:IAO_0000115 "Animals respond to an acetylcholinesterase inhibitor at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000500" ; a owl:Class ; rdfs:label "acetylcholinesterase inhibitor hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001290, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38462 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38462 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000501 obo:IAO_0000115 "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the left-handed direction. In liquid media, wave propogation is helical rather than planar." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Rol" ; oboInOwl:id "WBPhenotype:0000501" ; a owl:Class ; rdfs:label "left handed roller" ; rdfs:subClassOf obo:WBPhenotype_0000645 . obo:WBPhenotype_0000502 obo:IAO_0000115 "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern in the right-handed direction. In liquid media, wave propogation is helical rather than planar." ; oboInOwl:hasBroadSynonym "Rol" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000502" ; a owl:Class ; rdfs:label "right handed roller" ; rdfs:subClassOf obo:WBPhenotype_0000645 . obo:WBPhenotype_0000503 obo:IAO_0000115 "Any variation in the multiple rounds of DNA replication that take place without chromosome condensation, segregation or cytokinesis compared to control. In C. elegans this process is normally seen in intestinal nuclei during each larval lethargus which results in adult intestinal nuclei with 32 copies (32C) of each chromosome(Wormatlas)." ; oboInOwl:hasNarrowSynonym "endoreduplication abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000503" ; a owl:Class ; rdfs:label "endoreduplication variant" ; rdfs:subClassOf obo:WBPhenotype_0000433, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042023 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042023 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000504 obo:IAO_0000115 "Any variation in the process by which a cell nucleus is divided into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei, compared to control." ; oboInOwl:hasNarrowSynonym "nuclear division abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "karyokinesis abnormal" ; oboInOwl:id "WBPhenotype:0000504" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "nuclear division variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000280 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000280 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000505 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of any of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control animals. In C. elegans, nine bilateral rays project from the tail in a radial pattern with a smooth and slightly tapered appearance. Although one neuronal member of each ray sensillum is exposed to the outside, male rays rarely take up dye." ; oboInOwl:hasBroadSynonym "Ram" ; oboInOwl:hasNarrowSynonym "male ray morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000505" ; a owl:Class ; rdfs:label "male ray morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000299, obo:WBPhenotype_0001358, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000506 obo:IAO_0000115 "The adult male tail, including the lateral fan and rays, appears bloated or distended." ; oboInOwl:hasExactSynonym "swollen male tail" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000506" ; a owl:Class ; rdfs:label "bursa swollen" ; rdfs:subClassOf obo:WBPhenotype_0000342 . obo:WBPhenotype_0000507 obo:IAO_0000115 "Animals exhibit variations in the amount of acetylcholine compared to control animals at a defined stage. Acetylcholine is the acetic acid ester of the organic base choline." ; oboInOwl:hasNarrowSynonym "acetylcholine levels abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000507" ; a owl:Class ; rdfs:label "acetylcholine levels variant" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_15355 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_15355 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000508 obo:IAO_0000115 "Animals exhibit a decrease in the regulated breakdown of mRNA transcripts in which an amino-acid codon has changed to a premature stop codon and the 3 prime end is not protected by a poly(A) tail." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000508" ; a owl:Class ; rdfs:label "nonsense mRNA accumulation" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000184 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000184 ] ) ] ] . obo:WBPhenotype_0000509 obo:IAO_0000115 "Variation in the morphological appearance or composition of the pseudopod, a cellular projection that facilitates motility of the spermatozoa." ; oboInOwl:hasNarrowSynonym "sperm pseudopod abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000509" ; a owl:Class ; rdfs:label "sperm pseudopod variant" ; rdfs:subClassOf obo:WBPhenotype_0000388 . obo:WBPhenotype_0000510 obo:IAO_0000115 "The characteristic Christmas-tree shaped invagination formed by the terminal vulval cells at the mid-late L4 stage is altered." ; oboInOwl:hasAlternativeId "WBPhenotype:0000287" ; oboInOwl:hasNarrowSynonym "vulval invagination L4 abnormal", "vulval invagination abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "vulval invagination L4 variant" ; oboInOwl:id "WBPhenotype:0000510" ; a owl:Class ; rdfs:label "vulval invagination variant L4" ; rdfs:subClassOf obo:WBPhenotype_0000695, obo:WBPhenotype_0000699 . obo:WBPhenotype_0000511 obo:IAO_0000115 "Variations in the directed movement of the nucleus to a specific location within a cell compared to control." ; oboInOwl:hasNarrowSynonym "nuclear positioning abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "nuclear migration variant" ; oboInOwl:id "WBPhenotype:0000511" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "nuclear positioning variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0001344, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007097 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007097 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000512 obo:IAO_0000115 "Variations in spacing or location were observed between adjacent ventral cord nuclei or between ventral cord nuclei and another nucleus used as a reference point. In C. elegans, these nuclei are distributed equally and predictably, such that they can be unambiguously distinguished by their position." ; oboInOwl:hasNarrowSynonym "VNC nuclear positioning abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "VNC nuclear migration variant" ; oboInOwl:id "WBPhenotype:0000512" ; a owl:Class ; rdfs:label "VNC nuclear positioning variant" ; rdfs:subClassOf obo:WBPhenotype_0000511 . obo:WBPhenotype_0000513 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000315 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000513" ; a owl:Class ; rdfs:label "obsolete touch response abnormal" ; owl:deprecated true . obo:WBPhenotype_0000514 obo:IAO_0000115 "When prodded on the head, worm contracts and then relaxes along its entire body without moving backwards, compared to a control worm which contracts its anterior end and backs away in response to prodding." ; oboInOwl:hasBroadSynonym "Rbr" ; oboInOwl:hasExactSynonym "rubberband" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000514" ; a owl:Class ; rdfs:label "rubber band" ; rdfs:subClassOf obo:WBPhenotype_0000315 . obo:WBPhenotype_0000515 obo:IAO_0000115 "Variations in any process whose specific outcome is the development and/or maintenance of the ventral nerve cord." ; oboInOwl:hasNarrowSynonym "ventral nerve cord development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000515" ; a owl:Class ; rdfs:label "ventral nerve cord development variant" ; rdfs:subClassOf obo:WBPhenotype_0000945, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005829 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005829 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000516 obo:IAO_0000115 "The longitudinal nerve cord of the midbody region, connecting the nerve ring and tail ganglia, is not arranged in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000516" ; a owl:Class ; rdfs:label "ventral cord disorganized" ; rdfs:subClassOf obo:WBPhenotype_0000976, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000937 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005829 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000937 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005829 ] ) ] ] . obo:WBPhenotype_0000517 obo:IAO_0000115 "Variations in the specific actions or reactions in response to external or internal stimuli compared to that observed in control animals." ; oboInOwl:hasExactSynonym "behavior abnormal", "behavior variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000517" ; a owl:Class ; rdfs:label "behavior phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000519, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007610 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007610 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000518 obo:IAO_0000115 "Variations in the progression of an integrated living unit (a cell, tissue, organ or organism) over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasExactSynonym "development abnormal", "development variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000518" ; a owl:Class ; rdfs:label "development phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000519, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032502 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032502 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000519 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the cell, tissue, organ system or organism to carry out its normal functions and activities or be able to perceive and respond to stimuli compared to control animals." ; oboInOwl:hasExactSynonym "physiology abnormal", "physiology variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000519" ; a owl:Class ; rdfs:label "physiology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000886, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008150 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008150 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000520 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any of its parts compared to control animals." ; oboInOwl:hasExactSynonym "morphology abnormal", "morphology variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000520" ; a owl:Class ; rdfs:label "morphology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0002551, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000521 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency." ; oboInOwl:hasExactSynonym "pigmentation abnormal", "pigmentation variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000521" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "pigmentation phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000520, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000522 obo:IAO_0000115 "Variations in the specific actions or reactions of a certain defined body area of an animal in response to external or internal stimuli compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "organism region behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000522" ; a owl:Class ; rdfs:label "organism region behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000525 . obo:WBPhenotype_0000523 obo:IAO_0000115 "Animals exhibit variations in their response to a specific chemical compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "chemical response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000523" ; a owl:Class ; rdfs:label "chemical response variant" ; rdfs:subClassOf obo:WBPhenotype_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042221 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042221 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000524 obo:IAO_0000115 "Animals exhibit variations in their response to bleach compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "bleach response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000524" ; a owl:Class ; rdfs:label "bleach response variant" ; rdfs:subClassOf obo:WBPhenotype_0001379, obo:WBPhenotype_0001620, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1901530 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1901530 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000525 obo:IAO_0000115 "Variations in the specific actions or reactions of an organism in response to external or internal stimuli compared to that observed in control organisms." ; oboInOwl:hasNarrowSynonym "organism behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000525" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organism behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000517 . obo:WBPhenotype_0000526 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a cell." ; oboInOwl:hasExactSynonym "cell pigmentation abnormal", "cell pigmentation variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000526" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell pigmentation phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000521, obo:WBPhenotype_0000533, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000527 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism." ; oboInOwl:hasExactSynonym "organism pigmentation abnormal", "organism pigmentation variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Abnormal Coloration" ; oboInOwl:id "WBPhenotype:0000527" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organism pigmentation phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000521 . obo:WBPhenotype_0000528 obo:IAO_0000115 "Variations in the progression of the overall structure or appearance of a discrete region of an animal's anatomy over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "body region development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000528" ; a owl:Class ; rdfs:label "body region development variant" ; rdfs:subClassOf obo:WBPhenotype_0000531, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005738 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005738 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000529 obo:IAO_0000115 "Any variation in the progression of a cell from when it is first formed to when it becomes a mature structure when compared to control animals." ; oboInOwl:hasNarrowSynonym "cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000529" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000518, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048468 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048468 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000530 obo:IAO_0000115 "Any variation in the progression of an organismal system from its formation to the mature structure when compared to control animals." ; oboInOwl:hasNarrowSynonym "organ system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000530" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organ system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000518, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005746 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005746 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000531 obo:IAO_0000115 "Any variation in the progression of a worm at any time from its fertilization to adulthood compared to control." ; oboInOwl:hasNarrowSynonym "organism development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000531" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organism development variant" ; rdfs:subClassOf obo:WBPhenotype_0000518, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000532 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a discrete region of their anatomy compared to control animals." ; oboInOwl:hasNarrowSynonym "body region morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000532" ; a owl:Class ; rdfs:label "body region morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000535, obo:WBPhenotype_0002557, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005738 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005738 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000533 obo:IAO_0000115 "Any variation in the form or composition of the basic structural and functional unit of all organisms compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; oboInOwl:hasNarrowSynonym "cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000533" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000520, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004017 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000534 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that comprise a specific organ system." ; oboInOwl:hasNarrowSynonym "organ system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000534" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organ system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000520, obo:WBPhenotype_0002554, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005746 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005746 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000535 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any part of their anatomy compared to control animals." ; oboInOwl:hasBroadSynonym "Bmd" ; oboInOwl:hasNarrowSynonym "organism morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "body morphology defects" ; oboInOwl:id "WBPhenotype:0000535" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organism morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000520 . obo:WBPhenotype_0000536 obo:IAO_0000115 "Animals exhibit variations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for the cell to carry out its normal functions or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasExactSynonym "cell physiology abnormal", "cell physiology variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000536" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell physiology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000519, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0004017 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0004017 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000537 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000584 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000537" ; a owl:Class ; rdfs:label "obsolete synaptic input abnormal" ; owl:deprecated true . obo:WBPhenotype_0000538 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000584 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000538" ; a owl:Class ; rdfs:label "obsolete synaptic output abnormal" ; owl:deprecated true . obo:WBPhenotype_0000539 obo:IAO_0000115 "Variations in the progression of the anatomical structures that consist of processes of ventral cord motor neurons that send commissures to the dorsal side, as well as processes of certain head and tail neurons, over time from initial formation to mature structure compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "dorsal nerve cord development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000539" ; a owl:Class ; rdfs:label "dorsal nerve cord development variant" ; rdfs:subClassOf obo:WBPhenotype_0000945, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006750 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006750 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000540 obo:IAO_0000115 "Variations in the progression of the process extension from the muscle belly by which the muscle cells reach to the nerve cords to obtain innervation over time from initial formation to mature structure compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "muscle arm development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "muscle arm extension variant" ; oboInOwl:id "WBPhenotype:0000540" ; a owl:Class ; rdfs:label "muscle arm development variant" ; rdfs:subClassOf obo:WBPhenotype_0000087, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:GO_0036194 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:GO_0036194 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000541 obo:IAO_0000115 "Axon tracts fail to complete the connection between nerve cords. In C. elegans, these tracts grow circumferentially around the animal, completing the connection between the ventral and dorsal nerve cords." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000541" ; a owl:Class ; rdfs:label "cord commissures fail to reach target" ; rdfs:subClassOf obo:WBPhenotype_0000014 . obo:WBPhenotype_0000542 obo:IAO_0000115 "Animals exhibit an increased girth compared to a control animal of the same developmental stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "increased girth", "thick" ; oboInOwl:id "WBPhenotype:0000542" ; a owl:Class ; rdfs:label "fat" ; rdfs:subClassOf obo:WBPhenotype_0001727 . obo:WBPhenotype_0000543 obo:IAO_0000115 "Forward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves forward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000543" ; a owl:Class ; rdfs:label "forward kinker" ; rdfs:subClassOf obo:WBPhenotype_0000002 . obo:WBPhenotype_0000544 obo:IAO_0000115 "Backward movement is often characterized by severe bending motions, more sharply angled and/or much deeper than stereotypical sinusoidal body bends of the control. Animal moves backward with uncharacteristic loss of smooth sinusoidal motion or body posture (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000544" ; a owl:Class ; rdfs:label "backward kinker" ; rdfs:subClassOf obo:WBPhenotype_0000002 . obo:WBPhenotype_0000545 obo:IAO_0000115 "Eggs are retained in the uterus at a later stage when compared with control animals." ; oboInOwl:hasBroadSynonym "Ret" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "late eggs laid" ; oboInOwl:id "WBPhenotype:0000545" ; a owl:Class ; rdfs:label "egg retention" ; rdfs:subClassOf obo:WBPhenotype_0000006 . obo:WBPhenotype_0000546 obo:IAO_0000115 "Eggs are laid at an earlier stage of development when compared with control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000546" ; a owl:Class ; rdfs:label "early eggs laid" ; rdfs:subClassOf obo:WBPhenotype_0000005, obo:WBPhenotype_0000439, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] . obo:WBPhenotype_0000547 obo:IAO_0000115 "Animals exhibit morphological characteristics that are the outcome of nutrient deprivation. In C. elegans, starved worms have fewer refractile granules in intestinal cells, making them appear pale. Strongly starved mutants are small and thin, and tend to retain fewer eggs than control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Eat" ; oboInOwl:id "WBPhenotype:0000547" ; a owl:Class ; rdfs:label "starved" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0000548 obo:IAO_0000115 "Progressive degeneration of muscle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000548" ; a owl:Class ; rdfs:label "muscle dystrophy" ; rdfs:subClassOf obo:WBPhenotype_0000611, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001780 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003675 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001780 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003675 ] ) ] ] . obo:WBPhenotype_0000549 obo:IAO_0000115 "Progressive degeneration of the head muscle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000549" ; a owl:Class ; rdfs:label "head muscle dystrophy" ; rdfs:subClassOf obo:WBPhenotype_0000548, obo:WBPhenotype_0001002, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001780 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006761 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001780 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006761 ] ) ] ] . obo:WBPhenotype_0000550 obo:IAO_0000115 "Progressive degeneration of muscle along the body wall." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "body wall muscle dystrophy" ; oboInOwl:id "WBPhenotype:0000550" ; a owl:Class ; rdfs:label "body muscle dystrophy" ; rdfs:subClassOf obo:WBPhenotype_0000548, obo:WBPhenotype_0000596 . obo:WBPhenotype_0000551 obo:IAO_0000115 "Animals exhibit variations in the rate of sharp head to tail turns compared to control animals." ; oboInOwl:hasNarrowSynonym "omega turns abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000551" ; a owl:Class ; rdfs:label "omega turns variant" ; rdfs:subClassOf obo:WBPhenotype_0002311 . obo:WBPhenotype_0000552 obo:IAO_0000115 "Animals exhibit variations in the amount of GABA compared to control animals at a defined stage." ; oboInOwl:hasNarrowSynonym "GABA levels abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000552" ; a owl:Class ; rdfs:label "GABA levels variant" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_16865 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_16865 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000553 obo:IAO_0000115 "Animals exhibit a weak and abnormal birefringency pattern in muscle fibers when examined using polarized optics." ; oboInOwl:hasAlternativeId "WBPhenotype:0000714" ; oboInOwl:hasExactSynonym "Dim", "disorganized muscle" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "muscle birefringence abnormal" ; oboInOwl:id "WBPhenotype:0000553" ; a owl:Class ; rdfs:comment "Disorganized muscle fibers display a weak and abnormal birefringency pattern when examined using polarized optics." ; rdfs:label "muscle birefringence variant" ; rdfs:subClassOf obo:WBPhenotype_0000926 . obo:WBPhenotype_0000554 obo:IAO_0000115 "Any variation in the ability to adjust to a decline in ambient solute concentrations, thereby causing the body to swell and explode." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000554" ; a owl:Class ; rdfs:label "hypoosmotic shock hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000041 . obo:WBPhenotype_0000555 obo:IAO_0000115 "Animals show variations in their decreased responsiveness after prolonged or repeated exposure to a drug compared to that in control." ; oboInOwl:hasNarrowSynonym "drug adaptation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000555" ; a owl:Class ; rdfs:label "drug adaptation variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0000556 obo:IAO_0000115 "Animals show variations in their decreased responsiveness after prolonged or repeated exposure to dopamine compared to that in control." ; oboInOwl:hasNarrowSynonym "dopamine adaptation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000556" ; a owl:Class ; rdfs:label "dopamine adaptation variant" ; rdfs:subClassOf obo:WBPhenotype_0000555 . obo:WBPhenotype_0000557 obo:IAO_0000115 "Animals do not exhibit decreased responsiveness after prolonged or repeated exposure to dopamine." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000557" ; a owl:Class ; rdfs:label "dopamine adaptation defective" ; rdfs:subClassOf obo:WBPhenotype_0000556 . obo:WBPhenotype_0000558 obo:IAO_0000115 "Animals exhibit variations in their response to specific calcium channel modulators compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "calcium channel modulator response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000558" ; a owl:Class ; rdfs:label "calcium channel modulator response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0001833, obo:WBPhenotype_0002170 . obo:WBPhenotype_0000559 obo:IAO_0000115 "Animals respond to a calcium channel modulator at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000559" ; a owl:Class ; rdfs:label "calcium channel modulator hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0000558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38808 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38808 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000560 obo:IAO_0000115 "Animals fail to respond to the concentration of calcium channel modulators that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000560" ; a owl:Class ; rdfs:label "calcium channel modulator resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0000558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38808 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38808 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000561 obo:IAO_0000115 "The heads of animals fail to respond to the concentration of levamisole that elicits a response in control animals. In C. elegans, heads contract at >10uM for intact animals and >1uM for cut animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "head tetramisole resistant" ; oboInOwl:id "WBPhenotype:0000561" ; a owl:Class ; rdfs:label "head levamisole resistant" ; rdfs:subClassOf obo:WBPhenotype_0000421 . obo:WBPhenotype_0000562 obo:IAO_0000115 "The bodies of animals fail to respond to the concentration of levamisole that elicits a response in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "body tetramisole resistant" ; oboInOwl:id "WBPhenotype:0000562" ; a owl:Class ; rdfs:label "body levamisole resistant" ; rdfs:subClassOf obo:WBPhenotype_0000421 . obo:WBPhenotype_0000563 obo:IAO_0000115 "The whole body undergoes longitudinal shortening in response to head touch or tail touch (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000563" ; a owl:Class ; rdfs:label "shrinker" ; rdfs:subClassOf obo:WBPhenotype_0001701 . obo:WBPhenotype_0000564 obo:IAO_0000115 "Muscle contractions that make up the defecation motor program are repeated before the onset of the next cycle unlike in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000564" ; a owl:Class ; rdfs:label "echo defecation cycle" ; rdfs:subClassOf obo:WBPhenotype_0000207 . obo:WBPhenotype_0000565 obo:IAO_0000115 "The body of an animal assumes a coil-like shape when it attempts to move." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "curler" ; oboInOwl:id "WBPhenotype:0000565" ; a owl:Class ; rdfs:label "coiler" ; rdfs:subClassOf obo:WBPhenotype_0002297, obo:WBPhenotype_0004017 . obo:WBPhenotype_0000566 obo:IAO_0000115 "A coiling body that bends ventrally." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ventral curler" ; oboInOwl:id "WBPhenotype:0000566" ; a owl:Class ; rdfs:label "ventral coiler" ; rdfs:subClassOf obo:WBPhenotype_0000565 . obo:WBPhenotype_0000567 obo:IAO_0000115 "A coiling body that bends dorsally." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "dorsal curler" ; oboInOwl:id "WBPhenotype:0000567" ; a owl:Class ; rdfs:label "dorsal coiler" ; rdfs:subClassOf obo:WBPhenotype_0000565 . obo:WBPhenotype_0000568 obo:IAO_0000115 "Animals display variations in the structure or organization of the components of the axon, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "axon ultrastructure abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000568" ; a owl:Class ; rdfs:label "axon ultrastructure variant" ; rdfs:subClassOf obo:WBPhenotype_0000180 . obo:WBPhenotype_0000569 obo:IAO_0000115 "Animals display markedly swollen areas along their axons, which are larger than synaptic varicosities in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000569" ; a owl:Class ; rdfs:label "axon varicosities" ; rdfs:subClassOf obo:WBPhenotype_0000568 . obo:WBPhenotype_0000570 obo:IAO_0000115 "Axons of animals contain flattened membrane-bound compartments. In C. elegans, these cisternae-like structures are typically absent." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000570" ; a owl:Class ; rdfs:label "axon cisternae" ; rdfs:subClassOf obo:WBPhenotype_0000568 . obo:WBPhenotype_0000571 obo:IAO_0000115 "Axons of animals exhibit variations in the gross structure or organization of its spherical, membrane-bound, fluid-filled organelles, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "abnormal axon vesicle" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000571" ; a owl:Class ; rdfs:label "axon vesicle variant" ; rdfs:subClassOf obo:WBPhenotype_0000568 . obo:WBPhenotype_0000572 obo:IAO_0000115 "Any variation in the processes that govern the extension of neuronal projections." ; oboInOwl:hasNarrowSynonym "neuronal outgrowth abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000572" ; a owl:Class ; rdfs:label "neuronal outgrowth variant" ; rdfs:subClassOf obo:WBPhenotype_0000816 . obo:WBPhenotype_0000573 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0000633, obo:WBPhenotype_0001398 ; oboInOwl:hasNarrowSynonym "neuronal branching abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000573" ; a owl:Class ; rdfs:label "obsolete neuronal branching variant" ; owl:deprecated true . obo:WBPhenotype_0000574 obo:IAO_0000115 "The structure made by the processes of the excretory canal cell is reduced in size compared to control. In C. elegans this is an H-shaped structure which extends almost the full length of the body on both sides of the animal, generally in contact with the lateral hypodermis and the pseudocoelom (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000574" ; a owl:Class ; rdfs:label "excretory canal short" ; rdfs:subClassOf obo:WBPhenotype_0000704, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000574 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005775 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000574 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005775 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000575 obo:IAO_0000115 "Animals exhibit variations in a physical or chemical process required for organs or tissues to carry out their normal functions or for their ability to perceive and respond to stimuli compared to control." ; oboInOwl:hasExactSynonym "organ system physiology abnormal", "organ system physiology variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000575" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organ system physiology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000519, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005746 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005746 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000576 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the organism to carry out its normal function or be able to perceive and respond to stimuli." ; oboInOwl:hasExactSynonym "organism physiology abnormal", "organism physiology variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000576" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organism physiology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000519, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000577 obo:IAO_0000115 "Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the organism compared to control." ; oboInOwl:hasNarrowSynonym "organism homeostasis metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000577" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organism homeostasis metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000576 . obo:WBPhenotype_0000578 obo:IAO_0000115 "Variations in the progression of a discrete axis of an animal's anatomy over time, compared to control animals." ; oboInOwl:hasNarrowSynonym "body axis development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000578" ; a owl:Class ; rdfs:label "body axis development variant" ; rdfs:subClassOf obo:WBPhenotype_0000528, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005768 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005768 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000579 obo:IAO_0000115 "Variations in the progression of the overall structure or appearance of any anterior/posterior section of an animal's anatomy over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "organism segment development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000579" ; a owl:Class ; rdfs:label "organism segment development variant" ; rdfs:subClassOf obo:WBPhenotype_0000531 . obo:WBPhenotype_0000580 obo:IAO_0000115 "Variations in the specific actions or reactions of a certain body region of an animal in response to external or internal stimuli compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "organism segment behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000580" ; a owl:Class ; rdfs:label "organism segment behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000522 . obo:WBPhenotype_0000581 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a discrete axis (dorsal/ventral/anterior/posterior/transverse) of their anatomy, compared to control animals." ; oboInOwl:hasNarrowSynonym "body axis morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000581" ; a owl:Class ; rdfs:label "body axis morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000532, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005768 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005768 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000582 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any anterior/posterior section of their anatomy compared to control animals." ; oboInOwl:hasNarrowSynonym "organism segment morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000582" ; a owl:Class ; rdfs:label "organism segment morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000535 . obo:WBPhenotype_0000583 obo:IAO_0000115 "Worms are shorter and stouter than control animals at the same developmental stage." ; oboInOwl:hasBroadSynonym "Dpy" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000583" ; a owl:Class ; rdfs:label "dumpy" ; rdfs:subClassOf obo:WBPhenotype_0001726, obo:WBPhenotype_0001727 . obo:WBPhenotype_0000584 obo:IAO_0000115 "Any variation in the process of communication across a synapse between a neuron and a target cell (neuron, muscle, or secretory cell) compared to control animals." ; oboInOwl:hasAlternativeId "WBPhenotype:0000537", "WBPhenotype:0000538" ; oboInOwl:hasExactSynonym "synaptic input variant", "synaptic output variant" ; oboInOwl:hasNarrowSynonym "synaptic input abnormal", "synaptic output abnormal", "synaptic transmission abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000584" ; a owl:Class ; rdfs:label "synaptic transmission variant" ; rdfs:subClassOf obo:WBPhenotype_0002020, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007268 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007268 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000585 obo:IAO_0000115 "Variations in the chemical reactions and pathways involved in the maintenance of a steady-state at the level of the cell compared to control." ; oboInOwl:hasNarrowSynonym "cell homeostasis metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000585" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell homeostasis metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000536 . obo:WBPhenotype_0000586 obo:IAO_0000115 "Animals respond to bleach at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000586" ; a owl:Class ; rdfs:label "bleach hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000524, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_29222 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_29222 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000587 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0002072 ; oboInOwl:hasNarrowSynonym "lectin staining abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000587" ; a owl:Class ; rdfs:label "obsolete lectin staining variant" ; owl:deprecated true . obo:WBPhenotype_0000588 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:hasNarrowSynonym "no male abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000588" ; a owl:Class ; rdfs:comment "This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype." ; rdfs:label "obsolete no male variantity scored" ; owl:deprecated true . obo:WBPhenotype_0000589 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:hasNarrowSynonym "no hermaphrodite abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000589" ; a owl:Class ; rdfs:comment "This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype." ; rdfs:label "obsolete no hermaphrodite variantity scored" ; owl:deprecated true . obo:WBPhenotype_0000590 obo:IAO_0000115 "Animals exhibit differences in the number of cell corpses compared to controls at the same developmental life stage." ; oboInOwl:hasNarrowSynonym "cell corpse number abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000590" ; a owl:Class ; rdfs:label "cell corpse number variant" ; rdfs:subClassOf obo:WBPhenotype_0000730 . obo:WBPhenotype_0000591 obo:IAO_0000115 "Animals exhibit variations in their response to a specific metal compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "metal response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000591" ; a owl:Class ; rdfs:label "metal response variant" ; rdfs:subClassOf obo:WBPhenotype_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_33521 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_33521 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000592 obo:IAO_0000115 "Animals exhibit variations in their response to copper compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "copper response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000592" ; a owl:Class ; rdfs:label "copper response variant" ; rdfs:subClassOf obo:WBPhenotype_0000591, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_30052 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_30052 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000593 obo:IAO_0000115 "Animals respond to copper at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000593" ; a owl:Class ; rdfs:label "copper hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000592, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28694 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28694 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000594 obo:IAO_0000115 "Any variation in the orderly movement of a cell from one site to another." ; oboInOwl:hasBroadSynonym "Mig" ; oboInOwl:hasNarrowSynonym "cell migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "migration of cells abnormal" ; oboInOwl:id "WBPhenotype:0000594" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell migration variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016477 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016477 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000595 obo:IAO_0000115 "Variations in the specific actions or reactions of the head in response to external or internal stimuli compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "head behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000595" ; a owl:Class ; rdfs:label "head behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000580 . obo:WBPhenotype_0000596 obo:IAO_0000115 "Activity characteristic of the body is altered compared to control." ; oboInOwl:hasNarrowSynonym "body behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000596" ; a owl:Class ; rdfs:label "body behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000580 . obo:WBPhenotype_0000597 obo:IAO_0000115 "Variations in the specific actions or reactions of the tail in response to external or internal stimuli compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "tail behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000597" ; a owl:Class ; rdfs:label "tail behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000580 . obo:WBPhenotype_0000598 obo:IAO_0000115 "Variations in the form, structure or composition of the series of related tissues lying within the body cavity and devoted to feeding and digestion compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "alimentary system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000598" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "alimentary system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000534, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000599 obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the coelomic system, compared to control. The coelom is the fluid compartment that is in contact with internal organ." ; oboInOwl:hasNarrowSynonym "coelomic system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000599" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "coelomic system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000534, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005749 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005749 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000600 obo:IAO_0000115 "Variations in the form, composition or structure of the epithelial system that serves to protect the organism from the external environment compared to control." ; oboInOwl:hasNarrowSynonym "epithelial system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000600" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "epithelial system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000534, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005730 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005730 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000601 obo:IAO_0000115 "Variations in the form, structure or composition of related tissues that allow the animal to secrete saline fluid and maintain a proper salt balance compared to control. In C. elegans, four cell types (1 pore cell, 1 duct cell, 1 canal cell and a fused pair of gland cells) make up the excretory system (Wormatlas)." ; oboInOwl:hasAlternativeId "WBPhenotype:0000602" ; oboInOwl:hasExactSynonym "excretory system morphology variant" ; oboInOwl:hasNarrowSynonym "excretory secretory system morphology abnormal", "excretory system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000601" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "excretory secretory system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000534, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005736 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005736 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000602 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000601 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000602" ; a owl:Class ; rdfs:label "obsolete excretory system morphology abnormal" ; owl:deprecated true . obo:WBPhenotype_0000603 obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the muscle system, compared to control. The muscle system consists of tissues made up of various elongated cells that are specialized to contract and produce movement and mechanical work." ; oboInOwl:hasNarrowSynonym "muscle system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000603" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "muscle system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000534, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005737 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005737 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000604 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals." ; oboInOwl:hasNarrowSynonym "nervous system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "neuroanatomical defective" ; oboInOwl:id "WBPhenotype:0000604" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:comment "WB:WBbt:0005735." ; rdfs:label "nervous system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000534, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005735 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005735 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000605 obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." ; oboInOwl:hasNarrowSynonym "reproductive system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000605" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "reproductive system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000534, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005747 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005747 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000606 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the alimentary system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "alimentary system physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000606" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "alimentary system physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000575, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005748 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005748 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000607 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the coelomic system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "coelomic system physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000607" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "coelomic system physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000575, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005749 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005749 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000608 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the epithelial system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "epithelial system physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000608" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "epithelial system physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000575, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005730 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005730 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000609 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the excretory/secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "excretory secretory system physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000609" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "excretory secretory system physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000575, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006850 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006850 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000610 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the secretory system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "excretory system physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000610" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "excretory system physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000609, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005736 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005736 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000611 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "muscle system physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000611" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "muscle system physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000575, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005737 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005737 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000612 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the nervous system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "nervous system physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000612" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "nervous system physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000575, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005735 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005735 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000613 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the reproductive system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "reproductive system physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000613" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "reproductive system physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000575, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005747 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005747 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000614 obo:IAO_0000115 "Any variation in the progression of the GLR accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "GLR development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000614" ; a owl:Class ; rdfs:label "GLR development variant" ; rdfs:subClassOf obo:WBPhenotype_0000942, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005176 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005176 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000615 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the microtubule-based dendritic projections extending from the cell body, compared to that observed in control animals. In C. elegans, cilia are classified as channel cilia or wing cilia depending on their placement within the sensillum. Channel cilia of control animals are cylindrical, extend into the sensillum pore and are exposed to the outside. Wing cilia of control animals vary in shape, are embedded in the sensillum sheath cell and are not typically refractory to dyes indicating exposure to the outside." ; oboInOwl:hasNarrowSynonym "cilia morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "defective dye filling of cilia" ; oboInOwl:id "WBPhenotype:0000615" ; a owl:Class ; rdfs:label "cilia morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001526, obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000616 obo:IAO_0000115 "Animals display variations in the appearance of the subcellular junctional structure composed of a presynaptic terminal directly opposite the post-synaptic target and separated by a synaptic cleft." ; oboInOwl:hasNarrowSynonym "synapse morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000616" ; a owl:Class ; rdfs:label "synapse morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000604, obo:WBPhenotype_0001657, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045202 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045202 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000617 obo:IAO_0000115 "Any variation in the progression of the alimentary system over time, from its formation to its mature state compared to control. The alimentary system includes all the body structures involved in preparing food for absorption into the body and excretion of waste products." ; oboInOwl:hasNarrowSynonym "alimentary system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000617" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "alimentary system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005748 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005748 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000618 obo:IAO_0000115 "Any variation in the progression of the coelomic system over time, from its formation to its mature state compared to control." ; oboInOwl:hasNarrowSynonym "coelomic system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000618" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "coelomic system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005749 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005749 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000619 obo:IAO_0000115 "Any variation in the progression of the epithelial system over time, from its formation to its mature state compared to control." ; oboInOwl:hasNarrowSynonym "epithelial system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000619" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "epithelial system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005730 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005730 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000620 obo:IAO_0000115 "Any variation in the progression of the excretory secretory system over time, from its formation to its mature state compared to control. The excretory secretory system consists of the excretory system and its associated glands." ; oboInOwl:hasNarrowSynonym "excretory secretory system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000620" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "excretory secretory system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006850 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006850 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000621 obo:IAO_0000115 "Variations in the progression of the excretory system over time, from its formation to the mature structure. The excretory system is required for the elimination of metabolic waste. In C. elegans, the excretory system is comprised of the excretory cell, excretory duct cell and excretory socket cell." ; oboInOwl:hasNarrowSynonym "excretory system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000621" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "excretory system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000620, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005736 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005736 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000622 obo:IAO_0000115 "Any variation in the progression of the muscle system over time, from its formation to its mature state compared to control." ; oboInOwl:hasNarrowSynonym "muscle system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000622" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "muscle system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005737 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005737 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000623 obo:IAO_0000115 "Any variation in the progression of nervous tissue over time, from its formation to its mature state compared to control." ; oboInOwl:hasNarrowSynonym "nervous system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000623" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "nervous system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007399 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007399 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000624 obo:IAO_0000115 "Any variation in the progression of the reproductive system over time, from its formation to its mature state compared to control." ; oboInOwl:hasNarrowSynonym "reproductive system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "reproductive defect" ; oboInOwl:id "WBPhenotype:0000624" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "reproductive system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000530, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005747 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005747 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000625 obo:IAO_0000115 "Any variation in the biosynthesis of a synapse compared to control." ; oboInOwl:hasExactSynonym "synapse development variant" ; oboInOwl:hasNarrowSynonym "synaptogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000625" ; a owl:Class ; rdfs:label "synaptogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007416 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007416 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000626 obo:IAO_0000115 "Any variation in the decrease in a behavioral response to a repeated stimulus compared to control." ; oboInOwl:hasNarrowSynonym "habituation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "non associative learning variant" ; oboInOwl:id "WBPhenotype:0000626" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "habituation variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, obo:WBPhenotype_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0046959 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0046959 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000627 obo:IAO_0000115 "Animals exhibit variations in their response to a specific anesthetic compared to that observed in control animals." ; oboInOwl:hasExactSynonym "anaesthetic response variant" ; oboInOwl:hasNarrowSynonym "anesthetic response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000627" ; a owl:Class ; rdfs:label "anesthetic response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0072347 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0072347 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000628 obo:IAO_0000115 "Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000628" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "spindle assembly defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001102, obo:WBPhenotype_0002415 . obo:WBPhenotype_0000629 obo:IAO_0000115 "Any variation that causes an increase in the frequency of neurite (axon or dendrite) outgrowth. As a result, an excess number of neuronal projections are generated." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000629" ; a owl:Class ; rdfs:label "excess neurite outgrowth" ; rdfs:subClassOf obo:WBPhenotype_0000572 . obo:WBPhenotype_0000630 obo:IAO_0000115 "Failure to execute the characteristic response to the bitter tastant quinine, as defined by control animals. In C. elegans, quinine is typically repellent." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000630" ; a owl:Class ; rdfs:label "quinine chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001449, obo:WBPhenotype_0001454, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050919 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_15854 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050919 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_15854 ] ) ] ] . obo:WBPhenotype_0000631 obo:IAO_0000115 "Any variation in the characteristic response(s) to drug(s) as defined by control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "drug response abnormal" ; oboInOwl:id "WBPhenotype:0000631" ; a owl:Class ; rdfs:label "drug response variant" ; rdfs:subClassOf obo:WBPhenotype_0000523 . obo:WBPhenotype_0000632 obo:IAO_0000115 "The ability of axons to converge and form a bundle of nerve fibres (fascicle) is compromised." ; oboInOwl:hasNarrowSynonym "axon fasciculation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000632" ; a owl:Class ; rdfs:label "axon fasciculation variant" ; rdfs:subClassOf obo:WBPhenotype_0000880, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007413 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007413 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000633 obo:IAO_0000115 "Animals display variations in the number or pattern of axonal tracts stemming from the neuron cell body, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "axon branching abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000633" ; a owl:Class ; rdfs:label "axon branching variant" ; rdfs:subClassOf obo:WBPhenotype_0000180, obo:WBPhenotype_0001224 . obo:WBPhenotype_0000634 obo:IAO_0000115 "Any variation in the contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes compared to control." ; oboInOwl:hasNarrowSynonym "pharyngeal pumping abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000634" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "pharyngeal pumping variant" ; rdfs:subClassOf obo:WBPhenotype_0002056, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000635 obo:IAO_0000115 "Any variation in the directed movement of an animal in response to chemical attractants as defined by control animals." ; oboInOwl:hasNarrowSynonym "positive chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000635" ; a owl:Class ; rdfs:label "positive chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001434, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000636 obo:IAO_0000115 "Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals." ; oboInOwl:hasNarrowSynonym "neuron degeneration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000636" ; a owl:Class ; rdfs:label "neuron degeneration variant" ; rdfs:subClassOf obo:WBPhenotype_0000612 . obo:WBPhenotype_0000637 obo:IAO_0000115 "Characteristic entry into the dauer stage is altered compared to control animals." ; oboInOwl:hasBroadSynonym "Daf" ; oboInOwl:hasNarrowSynonym "dauer formation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000637" ; a owl:Class ; rdfs:label "dauer formation variant" ; rdfs:subClassOf obo:WBPhenotype_0000308 . obo:WBPhenotype_0000638 obo:IAO_0000115 "Animals exhibit defects in the process of periodic shedding, of part or all of its cuticle, during cuticle replacement that punctuates each larval stage." ; oboInOwl:hasBroadSynonym "Mlt", "Mult" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000638" ; a owl:Class ; rdfs:label "molt defect" ; rdfs:subClassOf obo:WBPhenotype_0002041 . obo:WBPhenotype_0000639 obo:IAO_0000115 "Animals exhibit variations in the entry into the dauer stage when exposed to temperatures that induce dauer formation in control animals. In C. elegans, many Daf-c animals enter dauer at 25C, whereas Hid animals enter dauer at 27C." ; oboInOwl:hasNarrowSynonym "temperature induced dauer formation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Hid" ; oboInOwl:id "WBPhenotype:0000639" ; a owl:Class ; rdfs:label "temperature induced dauer formation variant" ; rdfs:subClassOf obo:WBPhenotype_0000146, obo:WBPhenotype_0001539 . obo:WBPhenotype_0000640 obo:IAO_0000115 "Animals exhibit variations in the stage of eggs laid, egg laying cycle, number of eggs or egg laying in response to stimuli compared to control." ; oboInOwl:hasBroadSynonym "Egl" ; oboInOwl:hasNarrowSynonym "egg laying abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "oviposition abnormal" ; oboInOwl:id "WBPhenotype:0000640" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:comment "Visual inspection." ; rdfs:label "egg laying variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000641 obo:IAO_0000115 "Any variation in the degree of movement compared to control animals." ; oboInOwl:hasNarrowSynonym "activity level abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000641" ; a owl:Class ; rdfs:label "activity level variant" ; rdfs:subClassOf obo:WBPhenotype_0000643 . obo:WBPhenotype_0000642 obo:IAO_0000115 "Worms move forward or backward with an increased rate of body bends per minute compared to control animals." ; oboInOwl:hasBroadSynonym "Hya" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000642" ; a owl:Class ; rdfs:label "hyperactive" ; rdfs:subClassOf obo:WBPhenotype_0000641, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040011 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040011 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000643 obo:IAO_0000115 "Animals exhibit deviations in self-propelled movement on a solid medium compared to control animals." ; oboInOwl:hasBroadSynonym "Unc" ; oboInOwl:hasNarrowSynonym "locomotion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "movement defect", "uncoordinated" ; oboInOwl:id "WBPhenotype:0000643" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "locomotion variant" ; rdfs:subClassOf obo:WBPhenotype_0001206 . obo:WBPhenotype_0000644 obo:IAO_0000115 "Animals do not move and are not responsive to external mechanical stimulation." ; oboInOwl:hasBroadSynonym "Prl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Prz" ; oboInOwl:id "WBPhenotype:0000644" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "paralyzed" ; rdfs:subClassOf obo:WBPhenotype_0001213, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000763 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000763 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] . obo:WBPhenotype_0000645 obo:IAO_0000115 "The body of the animal rotates around its long axis as the animal moves, causing the animal to move in a circular pattern. In liquid media, wave propogation is helical rather than planar." ; oboInOwl:hasBroadSynonym "Rol" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000645" ; a owl:Class ; rdfs:label "roller" ; rdfs:subClassOf obo:WBPhenotype_0004017 . obo:WBPhenotype_0000646 obo:IAO_0000115 "Animals move more slowly compared with control animals." ; oboInOwl:hasBroadSynonym "Slu" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lethargic", "slow" ; oboInOwl:id "WBPhenotype:0000646" ; a owl:Class ; rdfs:label "sluggish" ; rdfs:subClassOf obo:WBPhenotype_0001213, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040011 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040011 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000647 obo:IAO_0000115 "Animals exhibit variations in any processes that lead to the successful transfer of sperm from one organism to another." ; oboInOwl:hasNarrowSynonym "copulation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000647" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "copulation variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007620 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007620 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000648 obo:IAO_0000115 "Any variation in the specific actions or reactions of the male that are associated with reproduction compared to control." ; oboInOwl:hasBroadSynonym "Cod" ; oboInOwl:hasNarrowSynonym "male mating abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000648" ; a owl:Class ; rdfs:label "male mating variant" ; rdfs:subClassOf obo:WBPhenotype_0000647, obo:WBPhenotype_0000888, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060179 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060179 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000649 obo:IAO_0000115 "Any variation in the male's ability to locate his partner's vulva when backing along the ventral side of the partner during mating compared to control. In C. elegans the male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate." ; oboInOwl:hasNarrowSynonym "vulva location abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Lov" ; oboInOwl:id "WBPhenotype:0000649" ; a owl:Class ; rdfs:label "vulva location variant" ; rdfs:subClassOf obo:WBPhenotype_0004006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034608 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034608 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000650 obo:IAO_0000115 "Animals exhibit variations in the processes involved in eliminating gut contents compared to control animals. In C. elegans the sequence of events during defecation includes posterior body contraction (pBoc), relaxation, anterior body contraction (aBoc), expulsion of gut contents by enteric muscle contraction (Emc) and opening of anus (Exp), and intercycle period (Wormatlas)." ; oboInOwl:hasNarrowSynonym "defecation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000650" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "defecation variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030421 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030421 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000651 obo:IAO_0000115 "Animals exhibit delayed or infrequent passage and/or expulsion of fecal matter." ; oboInOwl:hasBroadSynonym "Con" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000651" ; a owl:Class ; rdfs:label "constipated" ; rdfs:subClassOf obo:WBPhenotype_0000650, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030421 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030421 ] ) ] ] . obo:WBPhenotype_0000652 obo:IAO_0000115 "Variations in the progression of a set of interacting or interdependent entities forming the sensory system over time from an initial condition to a later condition compared to control animals. The sensory system is involved in the perception of a stimuli, its conversion into a signal and the recognition and characterization of the resulting signal." ; oboInOwl:hasAlternativeId "WBPhenotype:0000248" ; oboInOwl:hasNarrowSynonym "sensory system abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000652" ; a owl:Class ; rdfs:label "sensory system variant" ; rdfs:subClassOf obo:WBPhenotype_0000612 . obo:WBPhenotype_0000653 obo:IAO_0000115 "Variations in the progression of a set of interacting or interdependent entities forming the mechanosensory system over time from an initial condition to a later condition compared to control animals. The mechanosensory system is involved in the perception of a mechanical stimuli, its conversion into a signal and the recognition and characterization of the resulting signal." ; oboInOwl:hasNarrowSynonym "mechanosensory system abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000653" ; a owl:Class ; rdfs:label "mechanosensory system variant" ; rdfs:subClassOf obo:WBPhenotype_0000652 . obo:WBPhenotype_0000654 obo:IAO_0000115 "Animals exhibit variations in the fusion of intracellular neurotransmitter-filled membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell compared to control." ; oboInOwl:hasNarrowSynonym "synaptic vesicle exocytosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000654" ; a owl:Class ; rdfs:label "synaptic vesicle exocytosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000728, obo:WBPhenotype_0001684, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016079 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016079 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000655 obo:IAO_0000115 "Animals exhibit variations in the process of GABA neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control." ; oboInOwl:hasNarrowSynonym "GABA synaptic transmission abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000655" ; a owl:Class ; rdfs:label "GABA synaptic transmission variant" ; rdfs:subClassOf obo:WBPhenotype_0000584, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051932 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051932 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000656 obo:IAO_0000115 "Animals exhibit variations in the process of acetylcholine neurotransmitter-based communication from a neuron to a target cell across a synapse compared to control." ; oboInOwl:hasNarrowSynonym "acetylcholine synaptic transmission abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000656" ; a owl:Class ; rdfs:label "acetylcholine synaptic transmission variant" ; rdfs:subClassOf obo:WBPhenotype_0000584, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007271 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007271 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000657 obo:IAO_0000115 "Any variation in the process of information transfer between two neurons; usually in reference to chemical synapses, but can also be used to refer to electrical synapses compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "neuronal synaptic transmission abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000657" ; a owl:Class ; rdfs:label "neuronal synaptic transmission variant" ; rdfs:subClassOf obo:WBPhenotype_0000584 . obo:WBPhenotype_0000658 obo:IAO_0000115 "Any variation in the process of communication across a synapse between a neuron and a target muscle cell compared to control animals." ; oboInOwl:hasNarrowSynonym "neuromuscular synaptic transmission abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000658" ; a owl:Class ; rdfs:label "neuromuscular synaptic transmission variant" ; rdfs:subClassOf obo:WBPhenotype_0000584, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007274 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007274 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000659 obo:IAO_0000115 "Behavior associated with the intake of food is altered compared to control." ; oboInOwl:hasNarrowSynonym "feeding behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000659" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "feeding behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007631 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007631 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000660 obo:IAO_0000115 "Worms are found in clumps and/or crowded at the border of the bacterial lawn more frequently than control animals. This behavior is not due to mobility defects." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "bordering increased", "social behavior enhanced" ; oboInOwl:id "WBPhenotype:0000660" ; a owl:Class ; rdfs:label "social feeding increased" ; rdfs:subClassOf obo:WBPhenotype_0000659, obo:WBPhenotype_0001291 . obo:WBPhenotype_0000661 obo:IAO_0000115 "Animals disperse across a bacterial lawn and feed alone. When food is limiting, they can aggregate into swarms or clumps, but disperse once again when food is absent." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "solitary behavior enhanced", "solitary forager on food" ; oboInOwl:id "WBPhenotype:0000661" ; a owl:Class ; rdfs:label "solitary feeding increased" ; rdfs:subClassOf obo:WBPhenotype_0000659, obo:WBPhenotype_0001291 . obo:WBPhenotype_0000662 obo:IAO_0000115 "Variations in the behavior by which an organism locates food compared to control animals. In C. elegans roaming or dwelling activity on food are two examples of parameters used to assess this behavior. Roaming is defined as moving in a high-speed forward direction with brief backward movement, often traversing wide regions. Dwelling is defined as low-speed/high turning movement restricted to a confined region." ; oboInOwl:hasBroadSynonym "Fab" ; oboInOwl:hasNarrowSynonym "foraging behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000662" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "foraging behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060756 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060756 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000663 obo:IAO_0000115 "Animals exhibit variations in the avoidance response to solutions of a particular osmotic strength compared to control. In C. elegans, animals typically avoid solutions of high osmotic strength." ; oboInOwl:hasNarrowSynonym "osmotic avoidance abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Osm" ; oboInOwl:id "WBPhenotype:0000663" ; a owl:Class ; rdfs:label "osmotic avoidance variant" ; rdfs:subClassOf obo:WBPhenotype_0000481 . obo:WBPhenotype_0000664 obo:IAO_0000115 "The maximum ventral and dorsal flex of the animal is greater than that observed for control animals." ; oboInOwl:hasAlternativeId "WBPhenotype:0004021" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "loopy" ; oboInOwl:id "WBPhenotype:0000664" ; a owl:Class ; rdfs:label "exaggerated body bends" ; rdfs:subClassOf obo:WBPhenotype_0001703 . obo:WBPhenotype_0000665 obo:IAO_0000115 "Any variation that disrupts the connectivity between the somatic gonad and the adjoining tissues compared to control. In C. elegans this connnection is between the somatic gonad and the vulva in hermaphrodites and between the somatic gonad and proctodeum in males." ; oboInOwl:hasNarrowSynonym "connection of gonad abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Cog" ; oboInOwl:id "WBPhenotype:0000665" ; a owl:Class ; rdfs:label "connection of gonad variant" ; rdfs:subClassOf obo:WBPhenotype_0000605 . obo:WBPhenotype_0000666 obo:IAO_0000115 "Any variation that disrupts the release of a mature oocyte into the spermatheca (for subsequent fertilization), compared to control." ; oboInOwl:hasNarrowSynonym "ovulation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000666" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "ovulation variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030728 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030728 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000667 obo:IAO_0000115 "The specialized tissue of the reproductive tract that produces gamete is shifted from its customary place as defined by control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ectopic gonad" ; oboInOwl:id "WBPhenotype:0000667" ; a owl:Class ; rdfs:label "gonad displaced" ; rdfs:subClassOf obo:WBPhenotype_0000977 . obo:WBPhenotype_0000668 obo:IAO_0000115 "Any variation that results in the presence of mature oocytes with distended polyploid nuclei. In C. elegans, such oocytes mature and exit diakinesis, but are often not properly ovulated or fertilized." ; oboInOwl:hasBroadSynonym "Emo" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "arrest in meiosis I" ; oboInOwl:id "WBPhenotype:0000668" ; a owl:Class ; rdfs:label "endomitotic oocytes" ; rdfs:subClassOf obo:WBPhenotype_0001260 . obo:WBPhenotype_0000669 obo:IAO_0000115 "Variations in the progression of the muscles of the adult reproductive system over time form their initial formation to their mature structure compared to control." ; oboInOwl:hasNarrowSynonym "sex muscle development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000669" ; a owl:Class ; rdfs:label "sex muscle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000624, obo:WBPhenotype_0000860 . obo:WBPhenotype_0000670 obo:IAO_0000115 "Any variation in the processes that influence the generation and maturation of spermatozoa (motile sperm) compared to control." ; oboInOwl:hasBroadSynonym "Spe" ; oboInOwl:hasExactSynonym "spermatocyte germ cell differentiation abnormal" ; oboInOwl:hasNarrowSynonym "spermatogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000670" ; a owl:Class ; rdfs:label "spermatogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000894, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007283 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000671 obo:IAO_0000115 "Animals fail to respond to the concentration of copper that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to copper to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000671" ; a owl:Class ; rdfs:label "resistant to copper" ; rdfs:subClassOf obo:WBPhenotype_0000592, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28694 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28694 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000672 obo:IAO_0000115 "Animals display variations in the distribution of transmitter-filled vesicles in relation to the electron-dense membrane specialization of the neuron,compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "presynaptic vesicle cluster localization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "synaptic vesicle cluster localization abnormal" ; oboInOwl:id "WBPhenotype:0000672" ; a owl:Class ; rdfs:label "presynaptic vesicle cluster localization variant" ; rdfs:subClassOf obo:WBPhenotype_0000102 . obo:WBPhenotype_0000673 obo:IAO_0000115 "The number of offspring produced is altered compared to that of control animals." ; oboInOwl:hasNarrowSynonym "brood size abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000673" ; a owl:Class ; rdfs:label "brood size variant" ; rdfs:subClassOf obo:WBPhenotype_0000806, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000276 [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000276 [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000674 obo:IAO_0000115 "The developmental progression of an animal, from its formation to its mature structure occurs over a longer time period compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "retarded development" ; oboInOwl:id "WBPhenotype:0000674" ; a owl:Class ; rdfs:label "slow development" ; rdfs:subClassOf obo:WBPhenotype_0000043, obo:WBPhenotype_0000438, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032502 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032502 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000675 obo:IAO_0000115 "Animals die after fusion of gametes without dividing." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Emb" ; oboInOwl:id "WBPhenotype:0000675" ; a owl:Class ; rdfs:label "zygotic lethal" ; rdfs:subClassOf obo:WBPhenotype_0000213, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CL_0000365 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CL_0000365 ] ) ] ] . obo:WBPhenotype_0000676 obo:IAO_0000115 "The increase in size or mass of an organism over time during the lifespan of the organism or over any developmental stage(s) is not similar to that observed for control animals." ; oboInOwl:hasNarrowSynonym "growth rate abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000676" ; a owl:Class ; rdfs:label "growth rate variant" ; rdfs:subClassOf obo:WBPhenotype_0000030, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001492 [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001492 [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000677 obo:IAO_0000115 "Animals fail to receive, process or recognize a sensory chemical stimulus in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000677" ; a owl:Class ; rdfs:label "chemosensation defective" ; rdfs:subClassOf obo:WBPhenotype_0001050 . obo:WBPhenotype_0000678 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000678" ; a owl:Class ; rdfs:comment "This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype." ; rdfs:label "obsolete no copper sensitivity" ; owl:deprecated true . obo:WBPhenotype_0000679 obo:IAO_0000115 "Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals." ; oboInOwl:hasNarrowSynonym "transgene subcellular localization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000679" ; a owl:Class ; rdfs:label "transgene subcellular localization variant" ; rdfs:subClassOf obo:WBPhenotype_0000961 . obo:WBPhenotype_0000680 obo:IAO_0000115 "Animals exhibit variations in their response to aldicarb compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "aldicarb response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000680" ; a owl:Class ; rdfs:label "aldicarb response variant" ; rdfs:subClassOf obo:WBPhenotype_0001290, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_2555 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_2555 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000681 obo:IAO_0000115 "Animals exhibit variations in their response to DMPP compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "DMPP response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000681" ; a owl:Class ; rdfs:label "DMPP response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0000682 obo:IAO_0000115 "Hermaphrodites are transformed into fertile females; In C. elegans, XO fog animals are somatically male but produce oocytes instead of, or in addition to, sperm." ; oboInOwl:hasBroadSynonym "Fog" ; oboInOwl:hasExactSynonym "feminization of germ line" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000682" ; a owl:Class ; rdfs:label "feminization of germline" ; rdfs:subClassOf obo:WBPhenotype_0000687, obo:WBPhenotype_0000812, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000467 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040022 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000467 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040022 ] ) ] ] . obo:WBPhenotype_0000683 obo:IAO_0000115 "The germ line is sexually transformed from hermaphrodite to male. In C. elegans, XX mog animals are somatically hermaphrodite, but germ cells that normally would become oocytes are transformed into sperm." ; oboInOwl:hasBroadSynonym "Mog" ; oboInOwl:hasExactSynonym "masculinization of germ line" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000683" ; a owl:Class ; rdfs:label "masculinization of germline" ; rdfs:subClassOf obo:WBPhenotype_0000812, obo:WBPhenotype_0001572 . obo:WBPhenotype_0000684 obo:IAO_0000115 "Germ cell populations are reduced compared to control animals." ; oboInOwl:hasBroadSynonym "Fgc" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "germline underproliferation" ; oboInOwl:id "WBPhenotype:0000684" ; a owl:Class ; rdfs:label "fewer germ cells" ; rdfs:subClassOf obo:WBPhenotype_0000823, obo:WBPhenotype_0002174, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006796 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006796 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000685 obo:IAO_0000115 "Any variation that causes a reduction in growth rate during larval stages compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000685" ; a owl:Class ; rdfs:label "larval growth slow" ; rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0000676, obo:WBPhenotype_0001016 . obo:WBPhenotype_0000686 obo:IAO_0000115 "Animals exhibit variations in their response ionizing radiation compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "organism ionizing radiation response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000686" ; a owl:Class ; rdfs:label "organism ionizing radiation response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010212 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010212 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000687 obo:IAO_0000115 "Both hermaphrodites and males develop into fertile females." ; oboInOwl:hasBroadSynonym "Fem" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000687" ; a owl:Class ; rdfs:label "feminization of XX and XO animals" ; rdfs:subClassOf obo:WBPhenotype_0000049, obo:WBPhenotype_0000624, obo:WBPhenotype_0000822 . obo:WBPhenotype_0000688 obo:IAO_0000115 "Animals generate defective gametes, are otherwise unable to reproduce or they generate progeny that are unable to reproduce." ; oboInOwl:hasBroadSynonym "Ste" ; oboInOwl:hasExactSynonym "semi sterile" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000688" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "sterile" ; rdfs:subClassOf obo:WBPhenotype_0001384 . obo:WBPhenotype_0000689 obo:IAO_0000115 "Animals produce no or very few embryos as a result of experimental treatment. This is in contrast to sterility due to genetic perturbations (maternal effect sterility)." ; oboInOwl:hasBroadSynonym "Ste" ; oboInOwl:hasExactSynonym "Reduced fecundity of injected worm" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "sterile F0 fertility problems" ; oboInOwl:id "WBPhenotype:0000689" ; a owl:Class ; rdfs:label "maternal sterile" ; rdfs:subClassOf obo:WBPhenotype_0000694 . obo:WBPhenotype_0000690 obo:IAO_0000115 "Variations in the gross movement of the whole structure of the gonad along the body wall, behind the gonadal leader cell and away from the developing vulva compared to control (Wormatlas)." ; oboInOwl:hasBroadSynonym "Gom" ; oboInOwl:hasNarrowSynonym "gonad migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000690" ; a owl:Class ; rdfs:label "gonad migration variant" ; rdfs:subClassOf obo:WBPhenotype_0000624 . obo:WBPhenotype_0000691 obo:IAO_0000115 "Variations in the progression of the organ that produces gametes over time, from its formation to the mature structure compared to control." ; oboInOwl:hasNarrowSynonym "gonad development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Gon", "gonadogenesis abnormal" ; oboInOwl:id "WBPhenotype:0000691" ; a owl:Class ; rdfs:label "gonad development variant" ; rdfs:subClassOf obo:WBPhenotype_0000624, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008406 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008406 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000692 obo:IAO_0000115 "X0 animals fail to generate viable cross-progeny." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000692" ; a owl:Class ; rdfs:label "male sterile" ; rdfs:subClassOf obo:WBPhenotype_0000688, obo:WBPhenotype_0000863, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000956 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000956 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] . obo:WBPhenotype_0000693 obo:IAO_0000115 "Any perturbation that renders male derived sperm ineffective at fertilizing an oocyte." ; oboInOwl:hasBroadSynonym "Fer" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000693" ; a owl:Class ; rdfs:label "male sperm fertilization defect" ; rdfs:subClassOf obo:WBPhenotype_0000692 . obo:WBPhenotype_0000694 obo:IAO_0000115 "Hermaphrodites fail to generate viable self-progeny and/or cross-progeny." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000694" ; a owl:Class ; rdfs:label "hermaphrodite sterile" ; rdfs:subClassOf obo:WBPhenotype_0000688, obo:WBPhenotype_0001259, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000956 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007849 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000956 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007849 ] ) ] ] . obo:WBPhenotype_0000695 obo:IAO_0000115 "Animals exhibit variations in the gross structure or organization of the reproductive organ required for depositing eggs and for influencing male mating behavior compared to control." ; oboInOwl:hasNarrowSynonym "vulva morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000695" ; a owl:Class ; rdfs:label "vulva morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001335, obo:WBPhenotype_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000696 obo:IAO_0000115 "The eversion process, in which the vulval invagination is turned inside out during the final molt, is disrupted. In C.elegans, such variations in vulval eversion are primarily due to developmental defects in the somatic gonad (and sometimes vulva)." ; oboInOwl:hasBroadSynonym "Evl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000696" ; a owl:Class ; rdfs:label "everted vulva" ; rdfs:subClassOf obo:WBPhenotype_0000695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001597 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001597 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] ) ] ] . obo:WBPhenotype_0000697 obo:IAO_0000115 "Animals undergo incomplete vulval morphogenesis, resulting in the formation of a single protrusion at the site of the vulva." ; oboInOwl:hasBroadSynonym "Pvl", "Pvu" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000697" ; a owl:Class ; rdfs:label "protruding vulva" ; rdfs:subClassOf obo:WBPhenotype_0000695, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001598 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001598 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] ) ] ] . obo:WBPhenotype_0000698 obo:IAO_0000115 "No vulval tissue is produced. In C. elegans, this is usually a result of all six vulval precursor cells adopting a tertiary fate." ; oboInOwl:hasBroadSynonym "Vul" ; oboInOwl:hasExactSynonym "underinduced" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000698" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "vulvaless" ; rdfs:subClassOf obo:WBPhenotype_0000219, obo:WBPhenotype_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000699 obo:IAO_0000115 "Variations in the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure compared to control. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult." ; oboInOwl:hasNarrowSynonym "vulva development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000699" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "vulva development variant" ; rdfs:subClassOf obo:WBPhenotype_0000624, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040025 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040025 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000700 obo:IAO_0000115 "Multiple vulva-like protrusions are present along the ventral side of the animal. In C. elegans, this is usually a result of all six vulval precursor cells adopting primary or secondary vulval fates." ; oboInOwl:hasBroadSynonym "Muv" ; oboInOwl:hasExactSynonym "overinduced" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000700" ; a owl:Class ; rdfs:label "multivulva" ; rdfs:subClassOf obo:WBPhenotype_0000218, obo:WBPhenotype_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006748 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000701 obo:IAO_0000115 "Any variation in the progression of the epithelia over time, from its formation to its mature state compared to control. This process involves autonomously generated changes in epidermal cell shape and position, and interactions with internal tissues, including the developing nervous system and body wall muscles to affect epidermal enclosure, cell intercalation, and epidermal elongation." ; oboInOwl:hasNarrowSynonym "epithelial development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "epidermal morphogenesis variant" ; oboInOwl:id "WBPhenotype:0000701" ; a owl:Class ; rdfs:label "epithelial development variant" ; rdfs:subClassOf obo:WBPhenotype_0000619 . obo:WBPhenotype_0000702 obo:IAO_0000115 "Any perturbation that renders epithelial cells incompetent at undergoing membrane fusion during development." ; oboInOwl:hasDbXref "PMID:15341747" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000702" ; a owl:Class ; rdfs:label "epithelial cell fusion failure" ; rdfs:subClassOf obo:WBPhenotype_0000165, obo:WBPhenotype_0000701 . obo:WBPhenotype_0000703 obo:IAO_0000115 "Variations in the form, composition or structure of the layer of cells that cover the external surface of an organism and form the inner lining between the tissues and organs of that organism and the external environment compared to control. In C. elegans epithelial cells include epithelium of the alimentary tract, intestinal cells, hypodermis, interfacial cells and somatic gonad cells (Wormatlas)." ; oboInOwl:hasNarrowSynonym "epithelial morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "hypodermal morphology abnormal" ; oboInOwl:id "WBPhenotype:0000703" ; a owl:Class ; rdfs:label "epithelial morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000600 . obo:WBPhenotype_0000704 obo:IAO_0000115 "Variations in the form or composition of structures made by the processes of the excretory canal cell compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "excretory canal morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000704" ; a owl:Class ; rdfs:label "excretory canal morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000916, obo:WBPhenotype_0002558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005775 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005775 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000705 obo:IAO_0000115 "Any variation in the progression of an intestinal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "intestinal cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000705" ; a owl:Class ; rdfs:label "intestinal cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000708, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005792 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005792 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000706 obo:IAO_0000115 "Animals lack birefringent containing compartments in embryonic intestinal cells; however, these compartments appear in adult stages." ; oboInOwl:hasBroadSynonym "Glo" ; oboInOwl:hasDbXref "PMID:15843430" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "gut granule loss" ; oboInOwl:id "WBPhenotype:0000706" ; a owl:Class ; rdfs:label "gut granule biogenesis reduced" ; rdfs:subClassOf obo:WBPhenotype_0000103, obo:WBPhenotype_0001430 . obo:WBPhenotype_0000707 obo:IAO_0000115 "Variations in the progression of the pharynx (feeding organ) over time, from its formation to the mature structure compared to control. In C. elegans the pharynx is divided into the anterior and posterior regions. The anterior region includes the corpus (procorpus and metacorpus - first bulb) and the posterior region includes the isthmus and terminal bulb (second bulb)." ; oboInOwl:hasNarrowSynonym "pharyngeal development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000707" ; a owl:Class ; rdfs:label "pharyngeal development variant" ; rdfs:subClassOf obo:WBPhenotype_0000617, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060465 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060465 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000708 obo:IAO_0000115 "Variations in the progression of the intestine over time from its initial formation to its mature structure compared to control." ; oboInOwl:hasNarrowSynonym "intestinal development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "endoderm development abnormal", "gut development abnormal" ; oboInOwl:id "WBPhenotype:0000708" ; a owl:Class ; rdfs:label "intestinal development variant" ; rdfs:subClassOf obo:WBPhenotype_0000617, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048565 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048565 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000709 obo:IAO_0000115 "Variations in the form or composition of the mouthparts at the anterior end of the digestive tract which contain a series of radial muscles, related neurons and epithelial cells, and several gland cells which may aid in digestion compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "pharyngeal morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000709" ; a owl:Class ; rdfs:label "pharyngeal morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000598, obo:WBPhenotype_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000710 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion (Wormatlas)." ; oboInOwl:hasNarrowSynonym "intestinal morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000710" ; a owl:Class ; rdfs:label "intestinal morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000598, obo:WBPhenotype_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000711 obo:IAO_0000115 "Animals exhibit increased sensitivity to the effects of ion producing radiation compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000711" ; a owl:Class ; rdfs:label "organism hypersensitive ionizing radiation" ; rdfs:subClassOf obo:WBPhenotype_0000686 . obo:WBPhenotype_0000712 obo:IAO_0000115 "Germ cells exhibit variations in their response to ionizing radiation compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "germ cell ionizing radiation response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000712" ; a owl:Class ; rdfs:label "germ cell ionizing radiation response variant" ; rdfs:subClassOf obo:WBPhenotype_0000987, obo:WBPhenotype_0001324, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0071479 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006796 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0071479 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006796 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000713 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000981 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000713" ; a owl:Class ; rdfs:label "obsolete spermatocyte division abnormal" ; owl:deprecated true . obo:WBPhenotype_0000714 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000553 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000714" ; a owl:Class ; rdfs:label "obsolete disorganized muscle" ; owl:deprecated true . obo:WBPhenotype_0000715 obo:IAO_0000115 "Animals exhibit a greater number of embryonic muscle cells compared to control." ; oboInOwl:hasBroadSynonym "Mex" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000715" ; a owl:Class ; rdfs:label "muscle excess" ; rdfs:subClassOf obo:WBPhenotype_0000622, obo:WBPhenotype_0002175, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000716 obo:IAO_0000115 "Any variation in the connection of a cell whose principal function is to provide contractile forces with its neighboring cells or tissues compared to control." ; oboInOwl:hasNarrowSynonym "muscle cell attachment abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000716" ; a owl:Class ; rdfs:label "muscle cell attachment variant" ; rdfs:subClassOf obo:WBPhenotype_0000990 . obo:WBPhenotype_0000717 obo:IAO_0000115 "Variations in the processes that convert a gene's sequence into a mature gene product or products (proteins or RNA), compared to control." ; oboInOwl:hasNarrowSynonym "gene expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000717" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "gene expression variant" ; rdfs:subClassOf obo:WBPhenotype_0001696, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010467 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010467 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000718 obo:IAO_0000115 "Variations in the process of normalizing the expression level of X-linked genes between XX and XO animals compared to control." ; oboInOwl:hasNarrowSynonym "dosage compensation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000718" ; a owl:Class ; rdfs:comment "Possible XP GO:0007549." ; rdfs:label "dosage compensation variant" ; rdfs:subClassOf obo:WBPhenotype_0000717, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007549 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007549 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000719 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0000306, obo:WBPhenotype_0000717 ; oboInOwl:hasNarrowSynonym "reporter gene expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000719" ; a owl:Class ; rdfs:label "obsolete reporter gene expression variant" ; owl:deprecated true . obo:WBPhenotype_0000720 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0000111, obo:WBPhenotype_0000961 ; oboInOwl:hasNarrowSynonym "pattern of reporter gene expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000720" ; a owl:Class ; rdfs:label "obsolete pattern of reporter gene expression variant" ; owl:deprecated true . obo:WBPhenotype_0000721 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0000962 ; oboInOwl:hasExactSynonym "level of reporter gene expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000721" ; a owl:Class ; rdfs:label "obsolete level of reporter gene expression variant" ; owl:deprecated true . obo:WBPhenotype_0000722 obo:IAO_0000115 "Animals exhibit variations in the appearance of nucleoli compared to control animals." ; oboInOwl:hasNarrowSynonym "nucleolus abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000722" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "nucleolus variant" ; rdfs:subClassOf obo:WBPhenotype_0001028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005730 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005730 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000723 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000258 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000723" ; a owl:Class ; rdfs:label "obsolete cellular secretion abnormal" ; owl:deprecated true . obo:WBPhenotype_0000724 obo:IAO_0000115 "Variations in the regulated release of proteins from a cell or group of cells compared to control." ; oboInOwl:hasNarrowSynonym "protein secretion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000724" ; a owl:Class ; rdfs:label "protein secretion variant" ; rdfs:subClassOf obo:WBPhenotype_0000258, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009306 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009306 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000725 obo:IAO_0000115 "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of lipid within the organism or cell compared to control." ; oboInOwl:hasNarrowSynonym "lipid metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000725" ; a owl:Class ; rdfs:label "lipid metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006629 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006629 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000726 obo:IAO_0000115 "Any variation of the specific binding of a molecule to its partner, which typically results in a change in cell activity, compared to control." ; oboInOwl:hasNarrowSynonym "ligand binding abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000726" ; a owl:Class ; rdfs:label "ligand binding variant" ; rdfs:subClassOf obo:WBPhenotype_0000727 . obo:WBPhenotype_0000727 obo:IAO_0000115 "Any variation in the function of naturally occurring macromolecular substances known as enzymes compared to control. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ; oboInOwl:hasNarrowSynonym "enzyme activity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000727" ; a owl:Class ; rdfs:label "enzyme activity variant" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0003824 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0003824 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000728 obo:IAO_0000115 "Variations in the process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, compared to control." ; oboInOwl:hasNarrowSynonym "exocytosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000728" ; a owl:Class ; rdfs:label "exocytosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000258, obo:WBPhenotype_0001752, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006887 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006887 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000729 obo:IAO_0000115 "Animals exhibit variations in any of the processes that lead to the termination of vital functions of a cell." ; oboInOwl:hasBroadSynonym "Ced" ; oboInOwl:hasNarrowSynonym "cell death abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000729" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell death variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008219 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008219 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000730 obo:IAO_0000115 "Animals exhibit variations in any processes that influence the programmed cell death pathway. Induction of the apoptotic pathway triggers the activity of proteolytic caspases, which in turn lead to the destruction of the cell." ; oboInOwl:hasBroadSynonym "Ced" ; oboInOwl:hasNarrowSynonym "apoptosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000730" ; a owl:Class ; rdfs:label "apoptosis variant" ; rdfs:subClassOf obo:WBPhenotype_0001172, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000731 obo:IAO_0000115 "Germ cells exhibit increased sensitivity to the effects of ion producing radiation compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000731" ; a owl:Class ; rdfs:label "germ cell hypersensitive ionizing radiation" ; rdfs:subClassOf obo:WBPhenotype_0000712 . obo:WBPhenotype_0000732 obo:IAO_0000115 "Variations in any process that involves the maintenance, biosynthesis or accumulation of DNA in the organism compared to control." ; oboInOwl:hasNarrowSynonym "DNA metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000732" ; a owl:Class ; rdfs:label "DNA metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000463, obo:WBPhenotype_0000585, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006259 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006259 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000733 obo:IAO_0000115 "Any variation in the catalysis of a biochemical reaction compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component)." ; oboInOwl:hasNarrowSynonym "catalysis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000733" ; a owl:Class ; rdfs:label "catalysis variant" ; rdfs:subClassOf obo:WBPhenotype_0000727 . obo:WBPhenotype_0000734 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the hypodermal system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "hypodermal cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000734" ; a owl:Class ; rdfs:label "hypodermal cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000986, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007846 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007846 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000735 obo:IAO_0000115 "Any variation in the regulated re-replication of DNA in the hypodermal cells during a single cell cycle, compared to control." ; oboInOwl:hasNarrowSynonym "endoreduplication of hypodermal nuclei abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000735" ; a owl:Class ; rdfs:label "endoreduplication of hypodermal nuclei variant" ; rdfs:subClassOf obo:WBPhenotype_0000734 . obo:WBPhenotype_0000736 obo:IAO_0000115 "Animals exhibit variations in the process by which their cells digest parts of their own cytoplasm, compared to control." ; oboInOwl:hasExactSynonym "autophagy abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000736" ; a owl:Class ; rdfs:label "autophagy variant" ; rdfs:subClassOf obo:WBPhenotype_0000585, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006914 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006914 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000737 obo:IAO_0000115 "Germ cells fail to respond to the dosage of ion producing radiation that elicits a response in control animals. Alternatively, germ cells require a higher dosage or a longer exposure to ion producing radiation to elicit the same response as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000737" ; a owl:Class ; rdfs:label "germ cell resistant ionizing radiation" ; rdfs:subClassOf obo:WBPhenotype_0000712 . obo:WBPhenotype_0000738 obo:IAO_0000115 "The response to a change in the environment is altered compared to control." ; oboInOwl:hasNarrowSynonym "organism environmental stimulus response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000738" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "organism environmental stimulus response variant" ; rdfs:subClassOf obo:WBPhenotype_0000577, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009605 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009605 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000739 obo:IAO_0000115 "Variations in the activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism, compared to control." ; oboInOwl:hasNarrowSynonym "DNA damage response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000739" ; a owl:Class ; rdfs:label "DNA damage response variant" ; rdfs:subClassOf obo:WBPhenotype_0000142 . obo:WBPhenotype_0000740 obo:IAO_0000115 "Cells of the animals exhibit variations in the initiation, progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals." ; oboInOwl:hasNarrowSynonym "cell cycle abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000740" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell cycle variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007049 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007049 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000741 obo:IAO_0000115 "Mitotic cells exhibit variations in the execution of cell-cycle arrest in response to DNA damage." ; oboInOwl:hasNarrowSynonym "DNA damage checkpoint abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000741" ; a owl:Class ; rdfs:label "DNA damage checkpoint variant" ; rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0000740, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000077 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000077 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000742 obo:IAO_0000115 "Variations in the process by which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents, compared to control." ; oboInOwl:hasNarrowSynonym "DNA recombination abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000742" ; a owl:Class ; rdfs:label "DNA recombination variant" ; rdfs:subClassOf obo:WBPhenotype_0000732, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006310 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006310 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000743 obo:IAO_0000115 "Animals exhibit variations in their response to gene silencing triggered by double stranded RNA (RNAi), compared to control." ; oboInOwl:hasBroadSynonym "Rde" ; oboInOwl:hasNarrowSynonym "RNAi response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000743" ; a owl:Class ; rdfs:label "RNAi response variant" ; rdfs:subClassOf obo:WBPhenotype_0000577, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0016246 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0016246 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000744 obo:IAO_0000115 "Animals exhibit variations in the silencing of endogenous genes after introduction of repetitive exogenous cognate DNA compared to control." ; oboInOwl:hasNarrowSynonym "transgene induced cosuppression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000744" ; a owl:Class ; rdfs:label "transgene induced cosuppression variant" ; rdfs:subClassOf obo:WBPhenotype_0002063 . obo:WBPhenotype_0000745 obo:IAO_0000115 "Animals exhibit variations in the activity of endogenous transposons compared to control. In C. elegans transposon activity is often measured by the rate of reversion of mutations induced by transposon insertions." ; oboInOwl:hasNarrowSynonym "transposon silencing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000745" ; a owl:Class ; rdfs:label "transposon silencing variant" ; rdfs:subClassOf obo:WBPhenotype_0002063 . obo:WBPhenotype_0000746 obo:IAO_0000115 "Any variation that alters the physical partitioning and separation of a cell into daughter cells compared to control." ; oboInOwl:hasNarrowSynonym "cell division abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000746" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "cell division variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000747 obo:IAO_0000115 "Any defects in the muscle contractions that control feeding. Contractions are necessary for bacterial uptake from the surrounding environment." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000747" ; a owl:Class ; rdfs:label "pharyngeal contraction defective" ; rdfs:subClassOf obo:WBPhenotype_0000980 . obo:WBPhenotype_0000748 obo:IAO_0000115 "Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes)." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000748" ; a owl:Class ; rdfs:label "asymmetric cell division defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001585 . obo:WBPhenotype_0000749 obo:IAO_0000115 "Variations in the progression of an embryo over time, from zygote formation to hatching compared to control." ; oboInOwl:hasNarrowSynonym "embryonic development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "developmental defects detected in embryos" ; oboInOwl:id "WBPhenotype:0000749" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "embryonic development variant" ; rdfs:subClassOf obo:WBPhenotype_0000531, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000750 obo:IAO_0000115 "Variations in the progression of a larva over time, from its formation to the mature structure compared to control. The larva is the early, immature form of an animal between hatching and adulthood." ; oboInOwl:hasNarrowSynonym "larval development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000750" ; a owl:Class ; rdfs:label "larval development variant" ; rdfs:subClassOf obo:WBPhenotype_0000049, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000751 obo:IAO_0000115 "Variations in the progression of a newly hatched animal through the first larval molt compared to control." ; oboInOwl:hasNarrowSynonym "L1 larval development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000751" ; a owl:Class ; rdfs:label "L1 larval development variant" ; rdfs:subClassOf obo:WBPhenotype_0000750 . obo:WBPhenotype_0000752 obo:IAO_0000115 "Variations in the progression of the second larval stage compared to control." ; oboInOwl:hasNarrowSynonym "L2 larval development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000752" ; a owl:Class ; rdfs:label "L2 larval development variant" ; rdfs:subClassOf obo:WBPhenotype_0000750 . obo:WBPhenotype_0000753 obo:IAO_0000115 "Variations in the progression of the third larval stage compared to control." ; oboInOwl:hasNarrowSynonym "L3 larval development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000753" ; a owl:Class ; rdfs:label "L3 larval development variant" ; rdfs:subClassOf obo:WBPhenotype_0000750 . obo:WBPhenotype_0000754 obo:IAO_0000115 "Variations in the progression of the fourth larval stage compared to control." ; oboInOwl:hasNarrowSynonym "L4 larval development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000754" ; a owl:Class ; rdfs:label "L4 larval development variant" ; rdfs:subClassOf obo:WBPhenotype_0000750 . obo:WBPhenotype_0000755 obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L1 to L2 transition." ; oboInOwl:hasNarrowSynonym "L1 L2 molt abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "L1 molt" ; oboInOwl:id "WBPhenotype:0000755" ; a owl:Class ; rdfs:label "L1 L2 molt defect" ; rdfs:subClassOf obo:WBPhenotype_0000638 . obo:WBPhenotype_0000756 obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L2 to L3 transition." ; oboInOwl:hasNarrowSynonym "L2 L3 molt abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "L2 molt" ; oboInOwl:id "WBPhenotype:0000756" ; a owl:Class ; rdfs:label "L2 L3 molt defect" ; rdfs:subClassOf obo:WBPhenotype_0000638 . obo:WBPhenotype_0000757 obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L3 to L4 transition." ; oboInOwl:hasNarrowSynonym "L3 L4 molt abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "L3 molt" ; oboInOwl:id "WBPhenotype:0000757" ; a owl:Class ; rdfs:label "L3 L4 molt defect" ; rdfs:subClassOf obo:WBPhenotype_0000638 . obo:WBPhenotype_0000758 obo:IAO_0000115 "Animals exhibit defects in the process of shedding, part or all of its cuticle, during cuticle replacement that punctuates L4 to adult transition." ; oboInOwl:hasNarrowSynonym "L4 adult molt abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "L4 molt" ; oboInOwl:id "WBPhenotype:0000758" ; a owl:Class ; rdfs:label "L4 adult molt defect" ; rdfs:subClassOf obo:WBPhenotype_0000638 . obo:WBPhenotype_0000759 obo:IAO_0000115 "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle." ; oboInOwl:hasBroadSynonym "Emb", "Spd" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000759" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "spindle defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000764, obo:WBPhenotype_0001100, obo:WBPhenotype_0002414 . obo:WBPhenotype_0000760 obo:IAO_0000115 "The alignment of the spindle relative to other cellular structures in the cells of an embryo varies from that observed in control animals." ; oboInOwl:hasBroadSynonym "Emb", "Spn" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000760" ; a owl:Class ; rdfs:label "spindle orientation defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000761, obo:WBPhenotype_0001681 . obo:WBPhenotype_0000761 obo:IAO_0000115 "Early embryos exhibit defects in the placement or the alignment of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ; oboInOwl:hasBroadSynonym "Emb", "Spo" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Spi" ; oboInOwl:id "WBPhenotype:0000761" ; a owl:Class ; rdfs:label "spindle position orientation defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001102 . obo:WBPhenotype_0000762 obo:IAO_0000115 "Early embryos exhibit defects in the placement of the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ; oboInOwl:hasBroadSynonym "Abs", "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000762" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "spindle position defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000761, obo:WBPhenotype_0002416, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0000763 obo:IAO_0000115 "Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for an embryonic cell to carry out its normal function and activities or be able to perceive and respond to stimuli." ; oboInOwl:hasNarrowSynonym "embryonic cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000763" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "embryonic cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007028 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007028 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000764 obo:IAO_0000115 "Variations in the processes that are carried out at in the embryo which results in its formation or the arrangement of constituent parts, compared to control." ; oboInOwl:hasNarrowSynonym "embryonic cell organization biogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000764" ; a owl:Class ; rdfs:label "embryonic cell organization biogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000749, obo:WBPhenotype_0000763, obo:WBPhenotype_0010002 . obo:WBPhenotype_0000765 obo:IAO_0000115 "The embryos exhibit defects in the cell cycle process whereby the distance is lengthened between poles of the spindle." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000765" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "spindle elongation integrity defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001102 . obo:WBPhenotype_0000766 obo:IAO_0000115 "Any variation in the rotation of the centrosome-pronuclear complex after its migration toward the center of the embryo, compared to control." ; oboInOwl:hasBroadSynonym "Rot" ; oboInOwl:hasNarrowSynonym "centrosome pair and associated pronuclear rotation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000766" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "centrosome pair and associated pronuclear rotation variant" ; rdfs:subClassOf obo:WBPhenotype_0000764 . obo:WBPhenotype_0000767 obo:IAO_0000115 "Sparse or enlarged yolk granules." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000767" ; a owl:Class ; rdfs:label "integrity of membranous organelles defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000585, obo:WBPhenotype_0001100 . obo:WBPhenotype_0000768 obo:IAO_0000115 "Areas devoid of yolk granules throughout the embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "cytoplasmic structure abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Aberrant Cytoplasmic Structure", "cellular structure disorganized" ; oboInOwl:id "WBPhenotype:0000768" ; a owl:Class ; rdfs:label "cytoplasmic structure defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001081 . obo:WBPhenotype_0000769 obo:IAO_0000115 "Embryos exhibit defects in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control embryos." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000769" ; a owl:Class ; rdfs:label "cytoplasmic appearance defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001427 . obo:WBPhenotype_0000770 obo:IAO_0000115 "Animals exhibit variations in the appearance of embryonic cells compared to control." ; oboInOwl:hasNarrowSynonym "embryonic cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000770" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "embryonic cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007028 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007028 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000771 obo:IAO_0000115 "Centrosomes detach from the male pronucleus." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000771" ; a owl:Class ; rdfs:label "centrosome attachment defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000770, obo:WBPhenotype_0001100, obo:WBPhenotype_0001903 . obo:WBPhenotype_0000772 obo:IAO_0000115 "Daughter nuclei are deformed and stay close to central cortex, cytokinesis defects." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000772" ; a owl:Class ; rdfs:label "sister chromatid segregation defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000773, obo:WBPhenotype_0001078 . obo:WBPhenotype_0000773 obo:IAO_0000115 "Any variation in the processes that regulate the apportionment of chromosomes to each of two daughter cells compared to control." ; oboInOwl:hasNarrowSynonym "chromosome segregation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000773" ; a owl:Class ; rdfs:label "chromosome segregation variant" ; rdfs:subClassOf obo:WBPhenotype_0000585, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007059 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007059 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000774 obo:IAO_0000115 "Any variation in the processes that govern the generation and maintenance of gametes compared to control." ; oboInOwl:hasNarrowSynonym "gametogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000774" ; a owl:Class ; rdfs:label "gametogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000624, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007276 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007276 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000775 obo:IAO_0000115 "Variations in the specialized nuclear and cytoplasmic divisions of a single diploid cell, whose specific outcome is the formation of four haploid daughter cells compared to control. Meiosis occurs during the formation of gametes." ; oboInOwl:hasNarrowSynonym "meiosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Mei", "germ cell meiosis abnormal", "germ cell meiosis variant" ; oboInOwl:id "WBPhenotype:0000775" ; a owl:Class ; rdfs:label "meiosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000740, obo:WBPhenotype_0000746, obo:WBPhenotype_0000812, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051321 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051321 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000776 obo:IAO_0000115 "Male and female PNs not visible; embryo often fills egg shell completely." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "passage through meiosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000776" ; a owl:Class ; rdfs:label "passage through meiosis defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001041 . obo:WBPhenotype_0000777 obo:IAO_0000115 "Unextruded or resorbed polar body(ies) leading to an extra PNs in P0 and/or extra karyomeres in AB/P1." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "polar body extrusion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000777" ; a owl:Class ; rdfs:label "polar body extrusion defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000775, obo:WBPhenotype_0001147 . obo:WBPhenotype_0000778 obo:IAO_0000115 "Animals are unable to ingest nutrients at a rate similar to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000778" ; a owl:Class ; rdfs:label "feeding inefficient" ; rdfs:subClassOf obo:WBPhenotype_0000659, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001677 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007631 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001677 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007631 ] ) ] ] . obo:WBPhenotype_0000779 obo:IAO_0000115 "Cessation of development during the final stages of embryogenesis. In C. elegans, this stage normally occurs 620-800 min after the first cleavage at 20C and is the stage after elongation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000779" ; a owl:Class ; rdfs:label "late embryonic arrest" ; rdfs:subClassOf obo:WBPhenotype_0000867 . obo:WBPhenotype_0000780 obo:IAO_0000115 "Animals rotate back and forth around their longitudinal axes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000780" ; a owl:Class ; rdfs:label "shaker" ; rdfs:subClassOf obo:WBPhenotype_0001701 . obo:WBPhenotype_0000781 obo:IAO_0000115 "Any variation in the extremely thin elongated cytoplasmic filament, usually composed principally of actin protein to form a myofilament lattice, as in muscle cells compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "thin filament abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "thin filament variant" ; oboInOwl:id "WBPhenotype:0000781" ; a owl:Class ; rdfs:label "body wall muscle thin filament variant" ; rdfs:subClassOf obo:WBPhenotype_0001889 . obo:WBPhenotype_0000782 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a robust elongated cytoplasmic filament composed principally of myosin protein compared to control animals. In C. elegans, thick filaments also contain paramyosin and twitchin (Wormatlas)." ; oboInOwl:hasNarrowSynonym "thick filament abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "thick filament variant" ; oboInOwl:id "WBPhenotype:0000782" ; a owl:Class ; rdfs:label "body wall muscle thick filament variant" ; rdfs:subClassOf obo:WBPhenotype_0001889 . obo:WBPhenotype_0000783 obo:IAO_0000115 "Animals lack the planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000783" ; a owl:Class ; rdfs:label "M line absent" ; rdfs:subClassOf obo:WBPhenotype_0001891, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0031430 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005863 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0031430 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005863 ] ) ] ] . obo:WBPhenotype_0000784 obo:IAO_0000115 "Males exhibit variations in the time of onset or duration of the fertile period owing to differences in sperm competence and/or function compared to control animals." ; oboInOwl:hasNarrowSynonym "male fertility abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000784" ; a owl:Class ; rdfs:label "male fertility variant" ; rdfs:subClassOf obo:WBPhenotype_0000145, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000279 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000279 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] . obo:WBPhenotype_0000785 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular body part compared to control animals." ; oboInOwl:hasNarrowSynonym "body part pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000785" ; a owl:Class ; rdfs:label "body part pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0000278 . obo:WBPhenotype_0000786 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency along a particular body axis compared to control." ; oboInOwl:hasNarrowSynonym "body axis pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000786" ; a owl:Class ; rdfs:label "body axis pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0000278 . obo:WBPhenotype_0000787 obo:IAO_0000115 "Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the posterior body axis compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000787" ; a owl:Class ; rdfs:label "posterior pale" ; rdfs:subClassOf obo:WBPhenotype_0000984, obo:WBPhenotype_0001261 . obo:WBPhenotype_0000788 obo:IAO_0000115 "Animals have decreased accumulation or expression of biochromes or any other substances that causes increased translucency of the anterior body axis compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000788" ; a owl:Class ; rdfs:label "anterior pale" ; rdfs:subClassOf obo:WBPhenotype_0000971, obo:WBPhenotype_0001261 . obo:WBPhenotype_0000789 obo:IAO_0000115 "Animals respond to fluoxetine at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000789" ; a owl:Class ; rdfs:label "fluoxetine hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_5118 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_5118 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000790 obo:IAO_0000115 "Animals fail to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000790" ; a owl:Class ; rdfs:label "fluoxetine resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_5118 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_5118 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000791 obo:IAO_0000115 "The nose of an animal fails to respond to the concentration of fluoxetine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000791" ; a owl:Class ; rdfs:label "nose resistant to fluoxetine" ; rdfs:subClassOf obo:WBPhenotype_0000790 . obo:WBPhenotype_0000792 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the anatomy contained in the anterior region, compared to control animals." ; oboInOwl:hasExactSynonym "anterior region morphology variant" ; oboInOwl:hasNarrowSynonym "anterior body morphology abnormal", "anterior region morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000792" ; a owl:Class ; rdfs:label "anterior body morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0000581 . obo:WBPhenotype_0000793 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the anatomy contained in the posterior region, compared to control animals." ; oboInOwl:hasAlternativeId "WBPhenotype:0001490" ; oboInOwl:hasExactSynonym "posterior region morphology variant" ; oboInOwl:hasNarrowSynonym "posterior body morphology abnormal", "posterior region morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000793" ; a owl:Class ; rdfs:label "posterior body morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0000581 . obo:WBPhenotype_0000794 obo:IAO_0000115 "The posterior part of the worm exhibits a reduced girth compared to a control animal of the same developmental stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000794" ; a owl:Class ; rdfs:label "posterior body thin" ; rdfs:subClassOf obo:WBPhenotype_0000793 . obo:WBPhenotype_0000795 obo:IAO_0000115 "Variations in the specific actions or reactions of one of the longitudinal axes of the extended body of the worm in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." ; oboInOwl:hasNarrowSynonym "body axis behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000795" ; a owl:Class ; rdfs:label "body axis behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000522 . obo:WBPhenotype_0000796 obo:IAO_0000115 "The movement of the posterior part of the worm is not coordinated with the rest of the body." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000796" ; a owl:Class ; rdfs:label "posterior body uncoordinated" ; rdfs:subClassOf obo:WBPhenotype_0000797 . obo:WBPhenotype_0000797 obo:IAO_0000115 "Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the tail of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." ; oboInOwl:hasNarrowSynonym "posterior body behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000797" ; a owl:Class ; rdfs:label "posterior body behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000795 . obo:WBPhenotype_0000798 obo:IAO_0000115 "Variations in the specific actions or reactions of the longitudinal axis that spans from the midpoint to the tip of the head of an animal in response to external or internal stimuli compared to that observed in control animals (Wormatlas)." ; oboInOwl:hasNarrowSynonym "anterior body behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000798" ; a owl:Class ; rdfs:label "anterior body behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000795 . obo:WBPhenotype_0000799 obo:IAO_0000115 "Variations in the progression of an animal's anatomy contained in the anterior region over time, compared to control animals." ; oboInOwl:hasNarrowSynonym "anterior region development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000799" ; a owl:Class ; rdfs:label "anterior region development variant" ; rdfs:subClassOf obo:WBPhenotype_0000578 . obo:WBPhenotype_0000800 obo:IAO_0000115 "Variations in the progression of an animal's anatomy contained in the posterior region over time, compared to control animals." ; oboInOwl:hasNarrowSynonym "posterior region development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000800" ; a owl:Class ; rdfs:label "posterior region development variant" ; rdfs:subClassOf obo:WBPhenotype_0000578 . obo:WBPhenotype_0000801 obo:IAO_0000115 "Variations in the progression of an animal's anatomy contained in the ventral region over time, compared to control animals." ; oboInOwl:hasNarrowSynonym "ventral region development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000801" ; a owl:Class ; rdfs:label "ventral region development variant" ; rdfs:subClassOf obo:WBPhenotype_0000578 . obo:WBPhenotype_0000802 obo:IAO_0000115 "Variations in the progression of an animal's anatomy contained in the dorsal region over time, compared to control animals." ; oboInOwl:hasNarrowSynonym "dorsal region development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000802" ; a owl:Class ; rdfs:label "dorsal region development variant" ; rdfs:subClassOf obo:WBPhenotype_0000578 . obo:WBPhenotype_0000803 obo:IAO_0000115 "Variations in the progression of the anterior end of the animal over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "head development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000803" ; a owl:Class ; rdfs:label "head development variant" ; rdfs:subClassOf obo:WBPhenotype_0000579, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001227 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060322 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001227 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060322 ] ) ] ] . obo:WBPhenotype_0000804 obo:IAO_0000115 "Variations in the progression of the overall structure or appearance of the animal over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "body development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000804" ; a owl:Class ; rdfs:label "body development variant" ; rdfs:subClassOf obo:WBPhenotype_0000579 . obo:WBPhenotype_0000805 obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the tail over time, from its formation to the mature structure, compared to control. The tail includes the posterior region that spans from the rectum to the end." ; oboInOwl:hasNarrowSynonym "tail development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000805" ; a owl:Class ; rdfs:label "tail development variant" ; rdfs:subClassOf obo:WBPhenotype_0000528, obo:WBPhenotype_0000579, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005741 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005741 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000806 obo:IAO_0000115 "Hermaphrodites exhibit variations in the time of onset or duration of the fertile period, or variations in the production of viable offspring, including number and state of fertilized eggs laid, compared to controls." ; oboInOwl:hasNarrowSynonym "hermaphrodite fertility abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000806" ; a owl:Class ; rdfs:label "hermaphrodite fertility variant" ; rdfs:subClassOf obo:WBPhenotype_0000145, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000274 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007849 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000274 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007849 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000807 obo:IAO_0000115 "The descendants of the G1 or G2 exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "G lineages abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000807" ; a owl:Class ; rdfs:label "G lineages variant" ; rdfs:subClassOf obo:WBPhenotype_0000825 . obo:WBPhenotype_0000808 obo:IAO_0000115 "The descendants of the K precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "K lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000808" ; a owl:Class ; rdfs:label "K lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000825 . obo:WBPhenotype_0000809 obo:IAO_0000115 "The descendants of a male specific precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "male specific lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000809" ; a owl:Class ; rdfs:label "male specific lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000825 . obo:WBPhenotype_0000810 obo:IAO_0000115 "Any variation in the progression of a blast cell (precursor cell) over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "blast cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000810" ; a owl:Class ; rdfs:label "blast cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006783 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006783 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000811 obo:IAO_0000115 "Any variation in the progression of an epithelial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "epithelial cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000811" ; a owl:Class ; rdfs:label "epithelial cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002064 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002064 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000812 obo:IAO_0000115 "Variations in the progression of the immature germ cell over time, from its formation from precursors to the mature structure (gamete) compared to control." ; oboInOwl:hasNarrowSynonym "germ cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "germline development abnormal" ; oboInOwl:id "WBPhenotype:0000812" ; a owl:Class ; rdfs:label "germ cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000774, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007281 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007281 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000813 obo:IAO_0000115 "Any variation in the progression of a gland cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "gland cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000813" ; a owl:Class ; rdfs:label "gland cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0003670 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0003670 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000814 obo:IAO_0000115 "Any variation in the progression of a marginal cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A marginal cell is a pharyngeal cell that connects the basement membrane to the apices of the triangle-shaped pharyngeal lumen." ; oboInOwl:hasNarrowSynonym "marginal cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000814" ; a owl:Class ; rdfs:label "marginal cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000619, obo:WBPhenotype_0000707, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0003673 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0003673 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000815 obo:IAO_0000115 "Any variation in the progression of a muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "muscle cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000815" ; a owl:Class ; rdfs:label "muscle cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000622, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0055001 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0055001 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000816 obo:IAO_0000115 "Variations in the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "neuron development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000816" ; a owl:Class ; rdfs:label "neuron development variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048666 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048666 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000817 obo:IAO_0000115 "Variations in the progression of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) over time from an initial condition to a later condition compared to control animals (Wormatlas)." ; oboInOwl:hasNarrowSynonym "uterine vulval cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000817" ; a owl:Class ; rdfs:label "uterine vulval cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000529, obo:WBPhenotype_0000624, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006790 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006790 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000818 obo:IAO_0000115 "Activity characteristic of an adult worm is altered compared to control." ; oboInOwl:hasNarrowSynonym "adult behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000818" ; a owl:Class ; rdfs:label "adult behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000819, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030534 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030534 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000819 obo:IAO_0000115 "Behavior characteristic of postembryonic stage(s) is altered compared to control." ; oboInOwl:hasNarrowSynonym "postembryonic behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000819" ; a owl:Class ; rdfs:label "postembryonic behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0001000 . obo:WBPhenotype_0000820 obo:IAO_0000115 "Activity characteristic of an embryo is altered compared to control." ; oboInOwl:hasNarrowSynonym "embryonic behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000820" ; a owl:Class ; rdfs:label "embryonic behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0001000 . obo:WBPhenotype_0000821 obo:IAO_0000115 "Animals exhibit variations in sex-specific behaviors compared to control." ; oboInOwl:hasNarrowSynonym "sexually dimorphic behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000821" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "sexually dimorphic behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000525 . obo:WBPhenotype_0000822 obo:IAO_0000115 "Any variation in the processes that govern the sexually dimorphic development of germline or somatic tissue compared to control." ; oboInOwl:hasNarrowSynonym "sex determination abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "sex specific development abnormal" ; oboInOwl:id "WBPhenotype:0000822" ; a owl:Class ; rdfs:label "sex determination variant" ; rdfs:subClassOf obo:WBPhenotype_0000930, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007530 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007530 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000823 obo:IAO_0000115 "Nuclear divisions in the germ line are either expanded are reduced compared to control." ; oboInOwl:hasBroadSynonym "Glp" ; oboInOwl:hasExactSynonym "germ line proliferation abnormal" ; oboInOwl:hasNarrowSynonym "germline proliferation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "germ cell proliferation abnormal" ; oboInOwl:id "WBPhenotype:0000823" ; a owl:Class ; rdfs:label "germline proliferation variant" ; rdfs:subClassOf obo:WBPhenotype_0000812 . obo:WBPhenotype_0000824 obo:IAO_0000115 "The descendants of an embryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "embryonic cell lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000824" ; a owl:Class ; rdfs:label "embryonic cell lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000093 . obo:WBPhenotype_0000825 obo:IAO_0000115 "The descendants of a postembryonic precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "postembryonic cell lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000825" ; a owl:Class ; rdfs:label "postembryonic cell lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000093 . obo:WBPhenotype_0000826 obo:IAO_0000115 "The descendants of H1 or H2 cells exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "H lineages abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000826" ; a owl:Class ; rdfs:label "H lineages variant" ; rdfs:subClassOf obo:WBPhenotype_0000825 . obo:WBPhenotype_0000827 obo:IAO_0000115 "The descendants of any of the V precursor cells (V1-V6) exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "V lineages abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000827" ; a owl:Class ; rdfs:label "V lineages variant" ; rdfs:subClassOf obo:WBPhenotype_0000825 . obo:WBPhenotype_0000828 obo:IAO_0000115 "The descendants of TL or TR cells exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "T lineages abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000828" ; a owl:Class ; rdfs:label "T lineages variant" ; rdfs:subClassOf obo:WBPhenotype_0000825 . obo:WBPhenotype_0000829 obo:IAO_0000115 "The descendants of Q L or QR cells exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "Q lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000829" ; a owl:Class ; rdfs:label "Q lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000825, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008593 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008593 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000830 obo:IAO_0000115 "The descendants of the B cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "B lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000830" ; a owl:Class ; rdfs:label "B lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000809, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008608 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008608 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000831 obo:IAO_0000115 "The descendants of the Y cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "Y lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000831" ; a owl:Class ; rdfs:label "Y lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000809 . obo:WBPhenotype_0000832 obo:IAO_0000115 "The descendants of the C blastomere exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "C lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000832" ; a owl:Class ; rdfs:label "C lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000824, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008588 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008588 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000833 obo:IAO_0000115 "The descendants of the U cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "U lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000833" ; a owl:Class ; rdfs:label "U lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000809 . obo:WBPhenotype_0000834 obo:IAO_0000115 "The descendants of the E blastomere exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "E lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000834" ; a owl:Class ; rdfs:label "E lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000824, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005208 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005208 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000835 obo:IAO_0000115 "The descendants of the F cell (which divides only in the males) exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "F lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000835" ; a owl:Class ; rdfs:label "F lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000809 . obo:WBPhenotype_0000836 obo:IAO_0000115 "The descendants of a gonadal precursor cell exhibit altered developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "gonadal lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000836" ; a owl:Class ; rdfs:label "gonadal lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000825 . obo:WBPhenotype_0000837 obo:IAO_0000115 "The descendants of a gonadal precursor cell exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "hermaphrodite gonadal lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000837" ; a owl:Class ; rdfs:label "hermaphrodite gonadal lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000836 . obo:WBPhenotype_0000838 obo:IAO_0000115 "The descendants of a gonadal precursor cell exhibit altered developmental programs in the male compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "male gonadal lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000838" ; a owl:Class ; rdfs:label "male gonadal lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000809, obo:WBPhenotype_0000836 . obo:WBPhenotype_0000839 obo:IAO_0000115 "Z1 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "Z1 hermaphrodite lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000839" ; a owl:Class ; rdfs:label "Z1 hermaphrodite lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000837 . obo:WBPhenotype_0000840 obo:IAO_0000115 "Z4 descendants exhibit altered developmental programs in the hermaphrodite compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "Z4 hermaphrodite lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000840" ; a owl:Class ; rdfs:label "Z4 hermaphrodite lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000837 . obo:WBPhenotype_0000841 obo:IAO_0000115 "Z1 descendents exhibit altered developmental programs in the male compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "Z1 male lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000841" ; a owl:Class ; rdfs:label "Z1 male lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000838 . obo:WBPhenotype_0000842 obo:IAO_0000115 "Z4 descendants exhibit altered developmental programs in the male compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "Z4 male lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000842" ; a owl:Class ; rdfs:label "Z4 male lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000838 . obo:WBPhenotype_0000843 obo:IAO_0000115 "The number of cross progeny sired by males is reduced compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000843" ; a owl:Class ; rdfs:label "male mating efficiency reduced" ; rdfs:subClassOf obo:WBPhenotype_0000648 . obo:WBPhenotype_0000844 obo:IAO_0000115 "Pharyngeal pumping is not influenced by serotonin treatment in the same manner as control animals." ; oboInOwl:hasNarrowSynonym "serotonin induced pumping abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000844" ; a owl:Class ; rdfs:label "serotonin induced pumping variant" ; rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001232, obo:WBPhenotype_0001285 . obo:WBPhenotype_0000845 obo:IAO_0000115 "Animals exhibit variations in the response to the addition of levamisole compared to that observed in control animals. Levamisole is a cholinergic agonist." ; oboInOwl:hasNarrowSynonym "levamisole response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "tetramisole response abnormal" ; oboInOwl:id "WBPhenotype:0000845" ; a owl:Class ; rdfs:label "levamisole response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0000846 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process in the region of the vesicle-filled varicosities of the synapse compared to control." ; oboInOwl:hasNarrowSynonym "presynaptic region physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000846" ; a owl:Class ; rdfs:label "presynaptic region physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000584, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0098793 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000847 obo:IAO_0000115 "Animals display variations in the distribution of the constituents that make up the synaptic machinery such as those required for priming, docking or fusion of vesicles at the active zone, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "presynaptic component localization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "synaptic component localization abnormal", "synaptic machinery localization abnormal" ; oboInOwl:id "WBPhenotype:0000847" ; a owl:Class ; rdfs:label "presynaptic component localization variant" ; rdfs:subClassOf obo:WBPhenotype_0001321 . obo:WBPhenotype_0000848 obo:IAO_0000115 "The developmental progression of an animal over time, from its formation to its mature structure is delayed compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000848" ; a owl:Class ; rdfs:label "developmental delay" ; rdfs:subClassOf obo:WBPhenotype_0000438, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032502 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000502 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032502 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000849 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for an amphid to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "amphid physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000849" ; a owl:Class ; rdfs:label "amphid physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000652, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005391 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005391 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000850 obo:IAO_0000115 "Animal does not respond to stroking in the anterior body region with a hair or similar fiber compared to control. In C. elegans, the anterior region is defined as the body region that lies between the posterior bulb of the pharynx and the vulva." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "touch insensitive anterior body" ; oboInOwl:id "WBPhenotype:0000850" ; a owl:Class ; rdfs:label "touch resistant anterior body" ; rdfs:subClassOf obo:WBPhenotype_0000456 . obo:WBPhenotype_0000851 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the ciliated neuron to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "ciliated neuron physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000851" ; a owl:Class ; rdfs:label "ciliated neuron physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0002563, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006816 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006816 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000852 obo:IAO_0000115 "Variations in the progression of a free-floating spherical cell lying in the pseudocoelomic cavity of animals that can endocytose many compounds, possibly for immune surveillance, over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "coelomocyte development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000852" ; a owl:Class ; rdfs:label "coelomocyte development variant" ; rdfs:subClassOf obo:WBPhenotype_0000618, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005751 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005751 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000853 obo:IAO_0000115 "Variations in the bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum, compared to control." ; oboInOwl:hasNarrowSynonym "intraflagellar transport abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "IFT abnormal" ; oboInOwl:id "WBPhenotype:0000853" ; a owl:Class ; rdfs:label "intraflagellar transport variant" ; rdfs:subClassOf obo:WBPhenotype_0000851, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000854 obo:IAO_0000115 "Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is disrupted." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ift defective" ; oboInOwl:id "WBPhenotype:0000854" ; a owl:Class ; rdfs:label "intraflagellar transport defective" ; rdfs:subClassOf obo:WBPhenotype_0000853, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] ) ] ] . obo:WBPhenotype_0000855 obo:IAO_0000115 "Variations in the progression of the fluid-filled space which separates the body wall from internal organs over time from its initial formation to its mature form compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "pseudocoelom development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000855" ; a owl:Class ; rdfs:label "pseudocoelom development variant" ; rdfs:subClassOf obo:WBPhenotype_0000200, obo:WBPhenotype_0000528, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005745 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005745 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000856 obo:IAO_0000115 "Any variation in the progression of a gland cell of the secretory-excretory system over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "excretory gland cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000856" ; a owl:Class ; rdfs:label "excretory gland cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000620, obo:WBPhenotype_0000813, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005776 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005776 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000857 obo:IAO_0000115 "Variations in the progression of a protokidney cell with an internal lumen that is suggested to collect and secrete salt solutions outward via the excretory sinus, over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "excretory cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "excretory canal cell development abnormal" ; oboInOwl:id "WBPhenotype:0000857" ; a owl:Class ; rdfs:label "excretory cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000621, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005812 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005812 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000858 obo:IAO_0000115 "Variations in the progression of an interfacial epithelial cell which forms a lumen to receive the outflow of the excretory gland and excretory canal cells, over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "excretory duct cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000858" ; a owl:Class ; rdfs:label "excretory duct cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000621, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0004540 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0004540 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000859 obo:IAO_0000115 "Variations in the progression of an interfacial epithelial cell which links excretory duct to hypodermis, over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "excretory socket cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "excretory pore cell development abnormal" ; oboInOwl:id "WBPhenotype:0000859" ; a owl:Class ; rdfs:label "excretory socket cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000621, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0004534 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0004534 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000860 obo:IAO_0000115 "Variations in the progression of muscle cells that lack transverse striations in its constituent fibers and are almost always involuntary, over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "nonstriated muscle development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000860" ; a owl:Class ; rdfs:label "nonstriated muscle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000622, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005780 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005780 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000861 obo:IAO_0000115 "Any variation in the progression of the principal muscle cell type whose contractile activity generates body motion in the nematode over time compared to control. In C. elegans they consist of 95 unfused cells in the adult organized into four muscle quadrants. Their sarcomeres are obliquely striated and lie lengthwise along the body wall (Wormatlas)." ; oboInOwl:hasExactSynonym "body wall muscle development abnormal" ; oboInOwl:hasNarrowSynonym "body wall muscle cell development abnormal", "body wall muscle cell development variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "muscle belly development abnormal", "somatic muscle development abnormal", "striated muscle development abnormal" ; oboInOwl:id "WBPhenotype:0000861" ; a owl:Class ; rdfs:label "body wall muscle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000921, obo:WBPhenotype_0001292, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006804 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006804 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000862 obo:IAO_0000115 "Worms appears turgid or swollen as a result of an excess number of eggs being retained in the uterus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000862" ; a owl:Class ; rdfs:label "bloated" ; rdfs:subClassOf obo:WBPhenotype_0000545 . obo:WBPhenotype_0000863 obo:IAO_0000115 "Males exhibit a reduction in the production of new individuals owing to defects in sperm competence and/or function compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000863" ; a owl:Class ; rdfs:label "male fertility reduced" ; rdfs:subClassOf obo:WBPhenotype_0000784, obo:WBPhenotype_0001384, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001834 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001834 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] . obo:WBPhenotype_0000864 obo:IAO_0000115 "Cessation of development during the initial period of elongation. In C. elegans, this period refers to the conversion of the bean-shaped embryo into the two-fold- shaped embryo." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000864" ; a owl:Class ; rdfs:label "early elongation arrest" ; rdfs:subClassOf obo:WBPhenotype_0000867 . obo:WBPhenotype_0000865 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for a amphid sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "amphid sheath cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000865" ; a owl:Class ; rdfs:label "amphid sheath cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000849, obo:WBPhenotype_0000975, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006754 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006754 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000866 obo:IAO_0000115 "Germ cells fail to undergo meiotic differentiation to form mature gametes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000866" ; a owl:Class ; rdfs:label "germ cell arrest" ; rdfs:subClassOf obo:WBPhenotype_0000823 . obo:WBPhenotype_0000867 obo:IAO_0000115 "Cessation of development during any stage occurring after fertilization and until hatching compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000867" ; a owl:Class ; rdfs:label "embryonic arrest" ; rdfs:subClassOf obo:WBPhenotype_0000749, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000868 obo:IAO_0000115 "All parts of the animal are immobilized except for the head." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000868" ; a owl:Class ; rdfs:label "paralyzed body" ; rdfs:subClassOf obo:WBPhenotype_0000644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000763 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005738 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000763 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005738 ] ) ] ] . obo:WBPhenotype_0000869 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0001401 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000869" ; a owl:Class ; rdfs:label "obsolete mitochondria morphology variant muscle" ; owl:deprecated true . obo:WBPhenotype_0000870 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0001401 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000870" ; a owl:Class ; rdfs:label "obsolete mitochondria morphology variant epithelial" ; owl:deprecated true . obo:WBPhenotype_0000871 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0001402 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000871" ; a owl:Class ; rdfs:label "obsolete connected mitochondria epithelial" ; owl:deprecated true . obo:WBPhenotype_0000872 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0001402 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000872" ; a owl:Class ; rdfs:label "obsolete connected mitochodria muscle" ; owl:deprecated true . obo:WBPhenotype_0000873 obo:IAO_0000115 "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G1 phase of the mitotic cell cycle just before entry into S phase, compared to control cells." ; oboInOwl:hasNarrowSynonym "G1 checkpoint abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000873" ; a owl:Class ; rdfs:label "G1 checkpoint variant" ; rdfs:subClassOf obo:WBPhenotype_0000741, obo:WBPhenotype_0001743, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0044819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0044819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000874 obo:IAO_0000115 "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the G2 phase of the mitotic cell cycle just before entry into M phase, nuclear division, compared to control cells." ; oboInOwl:hasNarrowSynonym "G2 checkpoint abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000874" ; a owl:Class ; rdfs:label "G2 checkpoint variant" ; rdfs:subClassOf obo:WBPhenotype_0000741, obo:WBPhenotype_0001743, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0044818 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0044818 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000875 obo:IAO_0000115 "Mitotic cells exhibit variations during the passage through a cell cycle control point late in the S phase of the mitotic cell cycle, which ensures DNA replication is complete, compared to control cells." ; oboInOwl:hasNarrowSynonym "S phase checkpoint abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000875" ; a owl:Class ; rdfs:label "S phase checkpoint variant" ; rdfs:subClassOf obo:WBPhenotype_0000741, obo:WBPhenotype_0001743, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031573 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031573 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000876 obo:IAO_0000115 "Animals exhibit variations in their response to osmotic stress compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "organism osmotic stress response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000876" ; a owl:Class ; rdfs:label "organism osmotic stress response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006970 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006970 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000877 obo:IAO_0000115 "Any variation in the progression of a sheath cell of the amphid sensillum over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "amphid sheath cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000877" ; a owl:Class ; rdfs:label "amphid sheath cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000950, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006754 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006754 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000878 obo:IAO_0000115 "Any variation in the progression of a chemosensory neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "chemosensory neuron development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000878" ; a owl:Class ; rdfs:label "chemosensory neuron development variant" ; rdfs:subClassOf obo:WBPhenotype_0000816, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005837 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005837 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000879 obo:IAO_0000115 "Animals exhibit variations in the processes that are required to maintain the length of telomeric DNA from generation to generation compared to control." ; oboInOwl:hasNarrowSynonym "telomere length regulation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000879" ; a owl:Class ; rdfs:label "telomere length regulation variant" ; rdfs:subClassOf obo:WBPhenotype_0001673, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1904356 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1904356 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000880 obo:IAO_0000115 "Any variation in the processes that influence the generation of neuronal extensions, that carry efferent (outgoing) action potentials from the cell body towards target cells compared to control." ; oboInOwl:hasNarrowSynonym "axon development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "axonogenesis abnormal" ; oboInOwl:id "WBPhenotype:0000880" ; a owl:Class ; rdfs:label "axon development variant" ; rdfs:subClassOf obo:WBPhenotype_0000944, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0061564 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0061564 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000881 obo:IAO_0000115 "Animals exhibit variations in the placement of the microtuble-based dendritic projections in relation to the sensillum neuron, from that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000881" ; a owl:Class ; rdfs:label "cilia mislocalized" ; rdfs:subClassOf obo:WBPhenotype_0001526, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000628 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006816 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000628 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006816 ] ) ] ] . obo:WBPhenotype_0000882 obo:IAO_0000115 "Any variation in the processes that influence the generation of neuronal extensions, that carry afferent (incoming) action potentials towards the cell body compared to control." ; oboInOwl:hasNarrowSynonym "dendrite development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000882" ; a owl:Class ; rdfs:label "dendrite development variant" ; rdfs:subClassOf obo:WBPhenotype_0000944, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016358 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016358 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000883 obo:IAO_0000115 "Variations in the progression of the major zone of overlapping axons in the head, which encircles the isthmus of the pharynx to form a tightly packed ring-like structure on the outside of the pharynx, over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "nerve ring development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000883" ; a owl:Class ; rdfs:label "nerve ring development variant" ; rdfs:subClassOf obo:WBPhenotype_0000945, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006749 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006749 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000884 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of either of a set of two ciliated wing neurons, AWBL or AWBR, of the amphid sensilla, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "AWB morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000884" ; a owl:Class ; rdfs:comment "WBbt:0005671." ; rdfs:label "AWB morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000256, obo:WBPhenotype_0001526, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005671 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005671 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000885 obo:IAO_0000115 "Any variation in the removal of a cell corpse, by a neighboring cell or a phagocyte compared to control." ; oboInOwl:hasNarrowSynonym "engulfment abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "phagocytosis abnormal" ; oboInOwl:id "WBPhenotype:0000885" ; a owl:Class ; rdfs:label "engulfment variant" ; rdfs:subClassOf obo:WBPhenotype_0000730, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043652 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043652 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000886 obo:IAO_0000115 "Animals exhibit variations compared to a given control." ; oboInOwl:hasExactSynonym "Abnormal", "variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "not WT", "not wildtype" ; oboInOwl:id "WBPhenotype:0000886" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "nematode phenotype" . obo:WBPhenotype_0000887 obo:IAO_0000115 "Animals exhibit variations in hermaphrodite-specific behaviors compared to control." ; oboInOwl:hasNarrowSynonym "hermaphrodite behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000887" ; a owl:Class ; rdfs:label "hermaphrodite behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000821 . obo:WBPhenotype_0000888 obo:IAO_0000115 "Animals exhibit variations in male-specific behaviors compared to control." ; oboInOwl:hasNarrowSynonym "male behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000888" ; a owl:Class ; rdfs:label "male behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000821 . obo:WBPhenotype_0000889 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required to carry out sex-specific activities or to be able to perceive and respond to sex-specific stimuli compared to control." ; oboInOwl:hasNarrowSynonym "sexually dimorphic physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000889" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "sexually dimorphic physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000576 . obo:WBPhenotype_0000890 obo:IAO_0000115 "Larva exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals." ; oboInOwl:hasNarrowSynonym "larval pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000890" ; a owl:Class ; rdfs:label "larval pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0001009 . obo:WBPhenotype_0000891 obo:IAO_0000115 "Adult animals appear unusually transparent when compared to control." ; oboInOwl:hasBroadSynonym "Clr" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000891" ; a owl:Class ; rdfs:label "clear adult" ; rdfs:subClassOf obo:WBPhenotype_0000346, obo:WBPhenotype_0001010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000964 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000041 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000964 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000041 ] ) ] ] . obo:WBPhenotype_0000892 obo:IAO_0000115 "Nuclear divisions in the germ line of hermaphrodites are either expanded are reduced compared to control." ; oboInOwl:hasNarrowSynonym "hermaphrodite germline proliferation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "hermaphrodite germ cell proliferation abnormal", "hermaphrodite germ line proliferation abnormal" ; oboInOwl:id "WBPhenotype:0000892" ; a owl:Class ; rdfs:label "hermaphrodite germline proliferation variant" ; rdfs:subClassOf obo:WBPhenotype_0000823 . obo:WBPhenotype_0000893 obo:IAO_0000115 "Nuclear divisions in the germ line of male animals are either expanded are reduced compared to control." ; oboInOwl:hasNarrowSynonym "male germline proliferation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "male germ cell proliferation abnormal", "male germ line proliferation abnormal" ; oboInOwl:id "WBPhenotype:0000893" ; a owl:Class ; rdfs:label "male germline proliferation variant" ; rdfs:subClassOf obo:WBPhenotype_0000823 . obo:WBPhenotype_0000894 obo:IAO_0000115 "Variations in the ability of a relatively unspecialized cell to acquire the specialized features of a mature gamete compared to control." ; oboInOwl:hasNarrowSynonym "germ cell differentiation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000894" ; a owl:Class ; rdfs:label "germ cell differentiation variant" ; rdfs:subClassOf obo:WBPhenotype_0000774 . obo:WBPhenotype_0000895 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000670 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000895" ; a owl:Class ; rdfs:label "obsolete spermatocyte germ cell differentiation abnormal" ; owl:deprecated true . obo:WBPhenotype_0000896 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000186 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000896" ; a owl:Class ; rdfs:label "obsolete oocyte germ cell differentiation abnormal" ; owl:deprecated true . obo:WBPhenotype_0000897 obo:IAO_0000115 "Variations in the material made up of fibers forming a framework and support structure for body tissues and organs compared to control." ; oboInOwl:hasNarrowSynonym "connective tissue abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000897" ; a owl:Class ; rdfs:label "connective tissue development variant" ; rdfs:subClassOf obo:WBPhenotype_0000200 . obo:WBPhenotype_0000898 obo:IAO_0000115 "Any variation in the morphological appearance of blast cells compared to control animals." ; oboInOwl:hasNarrowSynonym "blast cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000898" ; a owl:Class ; rdfs:label "blast cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006783 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006783 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000899 obo:IAO_0000115 "Any variation in the morphological appearance of epithelial cells compared to control animals." ; oboInOwl:hasNarrowSynonym "epithelial cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000899" ; a owl:Class ; rdfs:label "epithelial cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003672 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003672 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000900 obo:IAO_0000115 "Any variation in the morphological appearance of germ cells compared to control animals." ; oboInOwl:hasNarrowSynonym "germ cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000900" ; a owl:Class ; rdfs:label "germ cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006796 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006796 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000901 obo:IAO_0000115 "Any variation in the morphological appearance of gland cells compared to control animals." ; oboInOwl:hasNarrowSynonym "gland cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000901" ; a owl:Class ; rdfs:label "gland cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003670 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003670 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000902 obo:IAO_0000115 "Any variation in the morphological appearance of intestinal cells compared to control animals." ; oboInOwl:hasNarrowSynonym "intestinal cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000902" ; a owl:Class ; rdfs:label "intestinal cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000710, obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005792 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005792 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000903 obo:IAO_0000115 "Any variation in the morphological appearance of marginal cells compared to control animals." ; oboInOwl:hasNarrowSynonym "marginal cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000903" ; a owl:Class ; rdfs:label "marginal cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000899, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003673 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003673 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000904 obo:IAO_0000115 "Any variation in the morphological appearance of muscle cells compared to control animals." ; oboInOwl:hasNarrowSynonym "muscle cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000904" ; a owl:Class ; rdfs:label "muscle cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000603, obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000905 obo:IAO_0000115 "Animals display variations in the structure or organization of components of the neuronal cell internal to the cell itself or in relation to the cellular environment compared to control. A neuron is a major cell type of nervous tissue specialized for transmission of information in the form of patterns of impulses." ; oboInOwl:hasNarrowSynonym "neuron morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000905" ; a owl:Class ; rdfs:comment "WBbt:0003679." ; rdfs:label "neuron morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000604, obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000906 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the epithelial cells that form the interface between the uterus and the vulva (likely via a multilayered set of flaps) compared to control animals (Wormatlas)." ; oboInOwl:hasNarrowSynonym "uterine vulval cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000906" ; a owl:Class ; rdfs:label "uterine vulval cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002108 . obo:WBPhenotype_0000907 obo:IAO_0000115 "Any variation in the structural appearance of the caudal opening of the rectum in the tail compared to control animals." ; oboInOwl:hasNarrowSynonym "anus morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000907" ; a owl:Class ; rdfs:label "anus morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000598, obo:WBPhenotype_0002558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005364 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005364 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000908 obo:IAO_0000115 "Any variation in the structural appearance of the epithelial chamber that links the genital and alimentary tracts to the exterior via the anus (cloacal opening) compared to control animals." ; oboInOwl:hasAlternativeId "WBPhenotype:0000343" ; oboInOwl:hasExactSynonym "cloaca morphology abnormal" ; oboInOwl:hasNarrowSynonym "cloacal morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000908" ; a owl:Class ; rdfs:label "cloacal morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000598, obo:WBPhenotype_0000605, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005774 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005774 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000909 obo:IAO_0000115 "Any variation in the structure or appearance of the cells that form a narrow passage connecting the posterior bulb of the pharynx to the anterior intestine compared to control. In C. elegans this valve is composed of 3 pairs of cells each forming a flattened disc-like ring and is lined by a layer of cuticle (Wormatlas)." ; oboInOwl:hasNarrowSynonym "pharyngeal intestinal valve morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000909" ; a owl:Class ; rdfs:label "pharyngeal intestinal valve morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005767 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005767 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000910 obo:IAO_0000115 "Any variation in the morphological appearance of the rectum compared to control animals." ; oboInOwl:hasNarrowSynonym "rectal morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000910" ; a owl:Class ; rdfs:label "rectal morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000598, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005773 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005773 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000911 obo:IAO_0000115 "Any variation in the morphological appearance of coelomocytes compared to control animals." ; oboInOwl:hasNarrowSynonym "coelomocyte morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000911" ; a owl:Class ; rdfs:label "coelomocyte morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000533, obo:WBPhenotype_0000599, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005751 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005751 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000912 obo:IAO_0000115 "Any variation in the morphological appearance of pericellular components compared to control animals." ; oboInOwl:hasNarrowSynonym "pericellular component morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000912" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "pericellular component morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000520 . obo:WBPhenotype_0000913 obo:IAO_0000115 "Any variation in the morphological appearance of the basal lamina compared to control animals." ; oboInOwl:hasNarrowSynonym "basal lamina morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000913" ; a owl:Class ; rdfs:label "basal lamina morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000600, obo:WBPhenotype_0001523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005604 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005604 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000914 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "excretory gland cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000914" ; a owl:Class ; rdfs:label "excretory gland cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000601, obo:WBPhenotype_0000901, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005776 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005776 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000915 obo:IAO_0000115 "Adults show deficiencies in chroma resulting in increased translucency." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000915" ; a owl:Class ; rdfs:label "pale adult" ; rdfs:subClassOf obo:WBPhenotype_0000346, obo:WBPhenotype_0001261, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000328 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000041 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000328 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000041 ] ) ] ] . obo:WBPhenotype_0000916 obo:IAO_0000115 "Any variation in the morphological appearance of the excretory cell compared to control animals." ; oboInOwl:hasNarrowSynonym "excretory cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "excretory canal cell morphology abnormal" ; oboInOwl:id "WBPhenotype:0000916" ; a owl:Class ; rdfs:label "excretory cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000533, obo:WBPhenotype_0000601, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005812 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005812 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000917 obo:IAO_0000115 "Any variation in the morphological appearance of the excretory duct cell compared to control animals." ; oboInOwl:hasNarrowSynonym "excretory duct cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000917" ; a owl:Class ; rdfs:label "excretory duct cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000601, obo:WBPhenotype_0000899, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004540 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004540 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000918 obo:IAO_0000115 "Any variation in the morphological appearance of the excretory socket cell compared to control animals." ; oboInOwl:hasNarrowSynonym "excretory socket cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000918" ; a owl:Class ; rdfs:label "excretory socket cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000601, obo:WBPhenotype_0000899, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004534 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004534 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000919 obo:IAO_0000115 "Any variation in the progression of the region of a body wall muscle cell that contains the myofilament lattice (adjacent to the hypodermis) over time, from its initial state to the fully differentiated state compared to control." ; oboInOwl:hasNarrowSynonym "spindle body wall muscle cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "filament lattice body wall muscle cell development abnormal", "spindle body wall muscle cell development variant" ; oboInOwl:id "WBPhenotype:0000919" ; a owl:Class ; rdfs:label "body wall muscle cell spindle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000087 . obo:WBPhenotype_0000920 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000861 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000920" ; a owl:Class ; rdfs:label "obsolete body wall muscle cell development variant" ; owl:deprecated true . obo:WBPhenotype_0000921 obo:IAO_0000115 "Variations in the progression of muscle cells that contain fibers that are divided by transverse bands into striations, over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "striated muscle development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000921" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "striated muscle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000622, obo:WBPhenotype_0000990, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005779 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005779 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000922 obo:IAO_0000115 "Any variation in the progression of somatic (striated) muscles that run longitudinally in males over time from its initial formation to its mature form compared to control. In C. elegans males have 3 additional sets of sex-specific longitudinal muscles (anterior and posterior outer, anterior and posterior inner, and caudal) that contribute to the body wall musculature (Wormatlas)." ; oboInOwl:hasNarrowSynonym "male longitudinal muscle development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000922" ; a owl:Class ; rdfs:label "male longitudinal muscle development variant" ; rdfs:subClassOf obo:WBPhenotype_0000860, obo:WBPhenotype_0000921, obo:WBPhenotype_0000930, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006909 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006909 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000923 obo:IAO_0000115 "Any variation in the morphological appearance of the nonstriated muscle compared to control animals." ; oboInOwl:hasNarrowSynonym "nonstriated muscle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000923" ; a owl:Class ; rdfs:label "nonstriated muscle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000904, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005780 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005780 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000924 obo:IAO_0000115 "Any variation in the morphological appearance of the striated muscle compared to control animals." ; oboInOwl:hasNarrowSynonym "striated muscle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000924" ; a owl:Class ; rdfs:label "striated muscle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000904, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005779 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005779 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000925 obo:IAO_0000115 "Any variation in the morphological appearance of the sex muscles compared to control animals." ; oboInOwl:hasNarrowSynonym "sex muscle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000925" ; a owl:Class ; rdfs:label "sex muscle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000923 . obo:WBPhenotype_0000926 obo:IAO_0000115 "Any variation in the morphological appearance of the body wall muscle compared to control animals." ; oboInOwl:hasNarrowSynonym "body wall muscle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Dim" ; oboInOwl:id "WBPhenotype:0000926" ; a owl:Class ; rdfs:label "body wall muscle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000924, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005813 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005813 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000927 obo:IAO_0000115 "Any variation in the morphological appearance of the male longitudinal muscle compared to control animals." ; oboInOwl:hasNarrowSynonym "male longitudinal muscle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000927" ; a owl:Class ; rdfs:label "male longitudinal muscle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000923, obo:WBPhenotype_0000924, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006909 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006909 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000928 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required to carry out male-specific activities or to be able to perceive and respond to male-specific stimuli compared to control." ; oboInOwl:hasNarrowSynonym "male physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000928" ; a owl:Class ; rdfs:label "male physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000889, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007850 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007850 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000929 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required to carry out hermaphrodite-specific activities or to be able to perceive and respond to hermaphrodite-specific stimuli compared to control." ; oboInOwl:hasNarrowSynonym "hermaphrodite physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000929" ; a owl:Class ; rdfs:label "hermaphrodite physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000889, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007849 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0007849 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000930 obo:IAO_0000115 "Variations in the progression of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "sexually dimorphic development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000930" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "sexually dimorphic development variant" ; rdfs:subClassOf obo:WBPhenotype_0000531, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005752 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005752 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000931 obo:IAO_0000115 "Animals exhibit variations in their response to bisphenol A compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "bisphenol A response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000931" ; a owl:Class ; rdfs:label "bisphenol A response variant" ; rdfs:subClassOf obo:WBPhenotype_0000523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_33216 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042221 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_33216 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042221 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000932 obo:IAO_0000115 "Animals respond to bisphenol A at a lower concentration or a shorter exposure time compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000932" ; a owl:Class ; rdfs:label "bisphenol A hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000931, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_33216 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_33216 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000933 obo:IAO_0000115 "The descendants of the MS blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "MS lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000933" ; a owl:Class ; rdfs:label "MS lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000824, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008627 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008627 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000934 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any of its parts during a given developmental stage compared to control animals." ; oboInOwl:hasNarrowSynonym "developmental morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000934" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "developmental morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000535 . obo:WBPhenotype_0000935 obo:IAO_0000115 "The descendants of the D blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "D lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000935" ; a owl:Class ; rdfs:label "D lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000824, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008589 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0008589 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000936 obo:IAO_0000115 "The descendants of the P4 blastomere exhibit any variation in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "P4 lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000936" ; a owl:Class ; rdfs:label "P4 lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000824 . obo:WBPhenotype_0000937 obo:IAO_0000115 "The descendants of the W precursor cell exhibit any variation in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "W lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000937" ; a owl:Class ; rdfs:label "W lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000825 . obo:WBPhenotype_0000938 obo:IAO_0000115 "The descendants of any of the V precursor cells (V1-V6) in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "male V lineages abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000938" ; a owl:Class ; rdfs:label "male V lineages variant" ; rdfs:subClassOf obo:WBPhenotype_0000809 . obo:WBPhenotype_0000939 obo:IAO_0000115 "The descendants of TL or TR cells in male animals exhibit any variation in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "male T lineages abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000939" ; a owl:Class ; rdfs:label "male T lineages variant" ; rdfs:subClassOf obo:WBPhenotype_0000809 . obo:WBPhenotype_0000940 obo:IAO_0000115 "The descendants of any of the P precursor cells (P1-P12) in male animals exhibit any variation in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "male P lineages abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000940" ; a owl:Class ; rdfs:label "male P lineages variant" ; rdfs:subClassOf obo:WBPhenotype_0000809 . obo:WBPhenotype_0000941 obo:IAO_0000115 "The descendants of the M precursor cell in male animals, exhibit any variation in developmental programs compared to their counterparts in control animals." ; oboInOwl:hasNarrowSynonym "male M lineage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000941" ; a owl:Class ; rdfs:label "male M lineage variant" ; rdfs:subClassOf obo:WBPhenotype_0000809 . obo:WBPhenotype_0000942 obo:IAO_0000115 "Any variation in the progression of an accessory cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. An accessory cell supports sensory neurons." ; oboInOwl:hasNarrowSynonym "accessory cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000942" ; a owl:Class ; rdfs:label "accessory cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005762 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005762 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000943 obo:IAO_0000115 "Any variation in the progression of a cluster of neuron cell bodies (somata) over time from its initial formation to its mature form compared to control." ; oboInOwl:hasNarrowSynonym "ganglion development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000943" ; a owl:Class ; rdfs:label "ganglion development variant" ; rdfs:subClassOf obo:WBPhenotype_0000623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005189 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005189 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000944 obo:IAO_0000115 "Variations in the progression of a neuronal extension (such as axons or dendrites) over time, from its formation to the mature structure compared to control." ; oboInOwl:hasNarrowSynonym "neurite development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000944" ; a owl:Class ; rdfs:label "neurite development variant" ; rdfs:subClassOf obo:WBPhenotype_0000816, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031175 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031175 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000945 obo:IAO_0000115 "Any variation in the progression of a dense feltwork of interwoven cytoplasmic processes of nerve cells (dendrites and axons) and support cells, over time from an initial condition to a later condition, compared to control." ; oboInOwl:hasNarrowSynonym "neuropil development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000945" ; a owl:Class ; rdfs:label "neuropil development variant" ; rdfs:subClassOf obo:WBPhenotype_0000623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:UBERON_0002606 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:UBERON_0002606 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000946 obo:IAO_0000115 "Variations in the progression of a set of interacting or interdependent entities forming the pharyngeal nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses." ; oboInOwl:hasNarrowSynonym "pharyngeal nervous system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000946" ; a owl:Class ; rdfs:label "pharyngeal nervous system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000623, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005440 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005440 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000947 obo:IAO_0000115 "Variations in the form, structure or composition of the material made up of fibers forming a framework and support structure for body tissues and organs compared to control." ; oboInOwl:hasNarrowSynonym "connective tissue morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000947" ; a owl:Class ; rdfs:label "connective tissue morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000912 . obo:WBPhenotype_0000948 obo:IAO_0000115 "Any variation in the appearance or structure of the rigid external coating which is secreted by the hypodermis, seam and some interfacial epithelial cells compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "cuticle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000948" ; a owl:Class ; rdfs:label "cuticle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000912, obo:WBPhenotype_0002558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000949 obo:IAO_0000115 "Any variation in the appearance of the body cavity compared to control. In C. elegans , an aberrancy in the psedocoelom can involve an accumulation of fluids or fluorescent reporters." ; oboInOwl:hasNarrowSynonym "pseudocoelom morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000949" ; a owl:Class ; rdfs:label "pseudocoelom morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000532, obo:WBPhenotype_0000912, obo:WBPhenotype_0002558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005745 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005745 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000950 obo:IAO_0000115 "Any variation in the progression of a neuronal sheath cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control. A neuronal sheath cell is a structural cell that forms a specialized environment surrounding the sensory endings of a neuron." ; oboInOwl:hasNarrowSynonym "neuronal sheath cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000950" ; a owl:Class ; rdfs:label "neuronal sheath cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000942, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005811 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005811 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000951 obo:IAO_0000115 "Any variation in the progression of a socket cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell compared to control." ; oboInOwl:hasNarrowSynonym "socket cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000951" ; a owl:Class ; rdfs:label "socket cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000942, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005750 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005750 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000952 obo:IAO_0000115 "Any variation in the progression of a cluster of neuron somata located close to the nerve ring over time from its initial formation to its mature form compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "anterior ganglion development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000952" ; a owl:Class ; rdfs:label "anterior ganglion development variant" ; rdfs:subClassOf obo:WBPhenotype_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005375 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005375 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000953 obo:IAO_0000115 "Any variation in the progression of the ganglion that lies dorsally beside the nerve ring in the head over time from its initial formation to its mature form compared to control. In C. elegans, It contains neuron cell bodies that send their neuronal processes into the ring and longitudinal nerves, but form no local neuropil separate from the nerve ring. The dorsal ganglion is in close contact with the dorsal hypodermal cord (Wormatlas)." ; oboInOwl:hasNarrowSynonym "dorsal ganglion development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000953" ; a owl:Class ; rdfs:label "dorsal ganglion development variant" ; rdfs:subClassOf obo:WBPhenotype_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005214 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005214 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000954 obo:IAO_0000115 "Any variation in the progression of the ganglion which lies above and behind the rectum in the tail, in close continuity with the anal hypodermal ridge over time from its initial formation to its mature form compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "dorsorectal ganglia development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000954" ; a owl:Class ; rdfs:label "dorsorectal ganglia development variant" ; rdfs:subClassOf obo:WBPhenotype_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005212 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005212 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000955 obo:IAO_0000115 "Any variation in the progression of the left and right lateral ganglia which lie beside the nerve ring in the head over time from its initial formation to its mature form compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "lateral ganglia development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000955" ; a owl:Class ; rdfs:label "lateral ganglia development variant" ; rdfs:subClassOf obo:WBPhenotype_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005105 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005105 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000956 obo:IAO_0000115 "Any variation in the progression of the left and right lumbar ganglia which lie behind the pre-anal ganglion in the tail, in lateral positions over time from its initial formation to its mature form compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "lumbar ganglia development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000956" ; a owl:Class ; rdfs:label "lumbar ganglia development variant" ; rdfs:subClassOf obo:WBPhenotype_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005830 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005830 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000957 obo:IAO_0000115 "Any variation in the progression of the neuron somata associated with the post-deirid over time from its initial formation to its mature form compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "posterior lateral ganglion development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000957" ; a owl:Class ; rdfs:label "posterior lateral ganglion development variant" ; rdfs:subClassOf obo:WBPhenotype_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005465 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005465 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000958 obo:IAO_0000115 "Any variation in the progression of the ganglion which lies at the posterior limit of the ventral nerve cord in the tail over time from its initial formation to its mature form compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "preanal ganglion development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000958" ; a owl:Class ; rdfs:label "preanal ganglion development variant" ; rdfs:subClassOf obo:WBPhenotype_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005448 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005448 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000959 obo:IAO_0000115 "Any variation in the progression of the ganglion which lies at the anterior limit of the ventral nerve cord, near the ventral ganglion and nerve ring in the head posterior to the excretory pore over time from its initial formation to its mature form compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "retrovesicular ganglion development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000959" ; a owl:Class ; rdfs:label "retrovesicular ganglion development variant" ; rdfs:subClassOf obo:WBPhenotype_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005656 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005656 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000960 obo:IAO_0000115 "Any variation in the progression of the ganglion which lies ventrally beside the nerve ring in the head, just anterior of the retrovesicular ganglion over time from its initial formation to its mature form compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "ventral ganglion development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000960" ; a owl:Class ; rdfs:label "ventral ganglion development variant" ; rdfs:subClassOf obo:WBPhenotype_0000943, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005298 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005298 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000961 obo:IAO_0000115 "Any variation in the cellular or subcellular pattern of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ; oboInOwl:hasNarrowSynonym "pattern of transgene expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000961" ; a owl:Class ; rdfs:label "pattern of transgene expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000111, obo:WBPhenotype_0000306 . obo:WBPhenotype_0000962 obo:IAO_0000115 "Any variation in the measured expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ; oboInOwl:hasNarrowSynonym "level of transgene expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000962" ; a owl:Class ; rdfs:label "level of transgene expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000306, obo:WBPhenotype_0002575 . obo:WBPhenotype_0000963 obo:IAO_0000115 "Males exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the organism compared to control animals." ; oboInOwl:hasNarrowSynonym "male pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000963" ; a owl:Class ; rdfs:label "male pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0000527, obo:WBPhenotype_0001024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002247 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000964 obo:IAO_0000115 "Animals fail to respond to the concentration of DMPP that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000964" ; a owl:Class ; rdfs:label "DMPP resistant" ; rdfs:subClassOf obo:WBPhenotype_0000681, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4290 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4290 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000965 obo:IAO_0000115 "Animals exhibit variations in the programmed cell death pathway that is triggered in cells other than germ cells and that is not subject to upstream checkpoint regulation." ; oboInOwl:hasNarrowSynonym "somatic cell death abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000965" ; a owl:Class ; rdfs:label "somatic cell death variant" ; rdfs:subClassOf obo:WBPhenotype_0001172 . obo:WBPhenotype_0000966 obo:IAO_0000115 "Progressive decrease in brood size culminating, over generations, in the loss of reproductive ability and thus becoming effectively sterile." ; oboInOwl:hasBroadSynonym "Mrt" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000966" ; a owl:Class ; rdfs:label "germline mortal" ; rdfs:subClassOf obo:WBPhenotype_0000987 . obo:WBPhenotype_0000967 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0001431 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000967" ; a owl:Class ; rdfs:comment "In the WS193 and WS200 versions of WormBase WBPhenotype:0000967 has term name \"male tail spike\"; In some older records the term ID WBPhenotype:0000967 had the term name \"male distal tip cell behavior abnormal\", which may reflect an earlier (now deprecated) usage of the term ID." ; rdfs:label "obsolete male tail spike" ; owl:deprecated true . obo:WBPhenotype_0000968 obo:IAO_0000115 "Any variation in the structure or appearance of the thin cuticle specialization found at the extreme posterior end of the tail compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000968" ; a owl:Class ; rdfs:label "tail spike variant" ; rdfs:subClassOf obo:WBPhenotype_0000073, obo:WBPhenotype_0002558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006979 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006979 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000969 obo:IAO_0000115 "Animals exhibit variations in the structure, organization or placement of the cells that support sensory neurons, compared to that observed in control animals. In C. elegans, this category collectively refers to socket cells, sheath cells, and structural cells, or their processes." ; oboInOwl:hasNarrowSynonym "accessory cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000969" ; a owl:Class ; rdfs:comment "WBbt:0005762." ; rdfs:label "accessory cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000533, obo:WBPhenotype_0000604, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005762 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005762 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000970 obo:IAO_0000115 "Embryos exhibit variations in the accumulation or expression of biochromes or any other substances that alter its transparency/translucency compared to control animals ." ; oboInOwl:hasNarrowSynonym "embryonic pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000970" ; a owl:Class ; rdfs:label "embryonic pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0001009 . obo:WBPhenotype_0000971 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of the anterior body axis compared to control." ; oboInOwl:hasNarrowSynonym "anterior pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000971" ; a owl:Class ; rdfs:label "anterior pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0000786 . obo:WBPhenotype_0000972 obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the glia-like support cell of neuronal sensilla that ensheathes the dendrite tips and or processes of neurons, from that observed in control animals. In C. elegans, sheath cells have highly invaginated and vesiculated surfaces, which provide a specialized environment for dendritic structures." ; oboInOwl:hasAlternativeId "WBPhenotype:0001529" ; oboInOwl:hasExactSynonym "sensilium sheath cell morphology variant" ; oboInOwl:hasNarrowSynonym "neuronal sheath cell morphology abnormal", "sensilium sheath cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000972" ; a owl:Class ; rdfs:label "neuronal sheath cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000899, obo:WBPhenotype_0000969, obo:WBPhenotype_0001528, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005811 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005811 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000973 obo:IAO_0000115 "Animals exhibit an increased frequency of exchange of genetic material between non-sister chromatids of a pair of homologues." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000973" ; a owl:Class ; rdfs:label "homologous recombination increased" ; rdfs:subClassOf obo:WBPhenotype_0000742, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035825 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035825 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000974 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required by a subset of interfacial cells to carry out its normal function or be able to perceive and respond to stimuli, compared to control. It can refer to socket cells, sheath cells and structural cells or their processes (Wormatlas)." ; oboInOwl:hasNarrowSynonym "accessory cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000974" ; a owl:Class ; rdfs:label "accessory cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000612, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005762 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005762 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000975 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for a neuronal sheath cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "neuronal sheath cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000975" ; a owl:Class ; rdfs:label "neuronal sheath cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000974, obo:WBPhenotype_0000986, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005811 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005811 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000976 obo:IAO_0000115 "Any variation in the developmental process that results in the creation of defined areas or spaces within the ventral cord to which cells respond and eventually are instructed to differentiate compared to control." ; oboInOwl:hasNarrowSynonym "ventral cord patterning abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000976" ; a owl:Class ; rdfs:label "ventral cord patterning variant" ; rdfs:subClassOf obo:WBPhenotype_0000515, obo:WBPhenotype_0002551, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000060 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005829 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000060 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005829 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000977 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the components of the gonad that are separate from the germline proper compared to control animals." ; oboInOwl:hasNarrowSynonym "somatic gonad morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000977" ; a owl:Class ; rdfs:label "somatic gonad morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001355, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005785 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005785 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000978 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the spermatheca to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "spermatheca physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000978" ; a owl:Class ; rdfs:label "spermatheca physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000929, obo:WBPhenotype_0001197, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005319 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005319 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000979 obo:IAO_0000115 "Animals exhibit defects in any physical or chemical process involved in the dilation of the distal spermatheca which is required for the oocyte exit from the gonad arm." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000979" ; a owl:Class ; rdfs:label "spermatheca dilation defective" ; rdfs:subClassOf obo:WBPhenotype_0000978 . obo:WBPhenotype_0000980 obo:IAO_0000115 "Any variation in the muscle contractions that control feeding compared to control. Contractions are necessary for bacterial uptake from the surrounding environment." ; oboInOwl:hasNarrowSynonym "pharyngeal contraction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000980" ; a owl:Class ; rdfs:label "pharyngeal contraction variant" ; rdfs:subClassOf obo:WBPhenotype_0000634 . obo:WBPhenotype_0000981 obo:IAO_0000115 "Animals exhibit variations in the meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids (non-motile sperm) compared to control." ; oboInOwl:hasAlternativeId "WBPhenotype:0000713" ; oboInOwl:hasExactSynonym "spermatocyte division variant" ; oboInOwl:hasNarrowSynonym "spermatocyte division abnormal", "spermatocyte meiosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000981" ; a owl:Class ; rdfs:label "spermatocyte meiosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000670, obo:WBPhenotype_0000987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_1903046 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006799 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_1903046 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006799 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000982 obo:IAO_0000115 "Animals exhibit variations in the ability of a relatively unspecialized spermatocyte to acquire the properties of a spermatid cell compared to control." ; oboInOwl:hasNarrowSynonym "spermatid maturation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000982" ; a owl:Class ; rdfs:label "spermatid maturation variant" ; rdfs:subClassOf obo:WBPhenotype_0000670 . obo:WBPhenotype_0000983 obo:IAO_0000115 "Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) during sexual reproduction." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000983" ; a owl:Class ; rdfs:label "fertilization defective" ; rdfs:subClassOf obo:WBPhenotype_0000613, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009566 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009566 ] ) ] ] . obo:WBPhenotype_0000984 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency of the posterior body axis compared to control." ; oboInOwl:hasNarrowSynonym "posterior pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000984" ; a owl:Class ; rdfs:label "posterior pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0000786 . obo:WBPhenotype_0000985 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the blast cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." ; oboInOwl:hasExactSynonym "blast cell physiology variant" ; oboInOwl:hasNarrowSynonym "blast cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000985" ; a owl:Class ; rdfs:label "blast cell physiology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006783 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006783 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000986 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the epithelial cell to carry out its normal functions or activities, compared to control animals." ; oboInOwl:hasNarrowSynonym "epithelial cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000986" ; a owl:Class ; rdfs:label "epithelial cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000608, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003672 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003672 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000987 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the germ cell to carry out its normal functions or activities or be able to perceive and respond to cues, compared to control animals." ; oboInOwl:hasNarrowSynonym "germ cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000987" ; a owl:Class ; rdfs:label "germ cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006796 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006796 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000988 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the gland cell to carry out its normal functions or activities or be able to perceive and respond to signals, compared to control animals." ; oboInOwl:hasNarrowSynonym "gland cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000988" ; a owl:Class ; rdfs:label "gland cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000536 . obo:WBPhenotype_0000989 obo:IAO_0000115 "Animals exhibit deviations at the cellular level, but not necessarily restricted to a single cell, in any physical or chemical process required for a marginal cell to carry out its normal function and activities or be able to perceive and respond to stimuli." ; oboInOwl:hasNarrowSynonym "marginal cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000989" ; a owl:Class ; rdfs:label "marginal cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000986, obo:WBPhenotype_0001190, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003673 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003673 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000990 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the muscle cell to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "muscle cell physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000990" ; a owl:Class ; rdfs:label "muscle cell physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000611, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003675 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003675 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0000991 obo:IAO_0000115 "OBSOLETE: Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes." ; obo:IAO_0100001 obo:WBPhenotype_0002563 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000991" ; a owl:Class ; rdfs:label "obsolete neuron physiology variant" ; owl:deprecated true . obo:WBPhenotype_0000992 obo:IAO_0000115 "Failure to execute the characteristic response to high concentrations of sodium chloride solution. C. elegans typically avoids high concentrations of sodium chloride solution." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000992" ; a owl:Class ; rdfs:label "high sodium chloride concentration osmotic avoidance defective" ; rdfs:subClassOf obo:WBPhenotype_0000249, obo:WBPhenotype_0001453 . obo:WBPhenotype_0000993 obo:IAO_0000115 "Animals fail to contract the anal depressor muscle." ; oboInOwl:hasBroadSynonym "Exp" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000993" ; a owl:Class ; rdfs:label "anal depressor contraction defect" ; rdfs:subClassOf obo:WBPhenotype_0001092 . obo:WBPhenotype_0000994 obo:IAO_0000115 "Any variations in the contraction of the enteric muscles that are involved in defecation motor program compared to control." ; oboInOwl:hasNarrowSynonym "intestinal contractions abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Emc", "enteric muscle contraction variant" ; oboInOwl:id "WBPhenotype:0000994" ; a owl:Class ; rdfs:label "intestinal contractions variant" ; rdfs:subClassOf obo:WBPhenotype_0000210 . obo:WBPhenotype_0000995 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000995" ; a owl:Class ; rdfs:comment "WBPhenotype:0000995 an alt_id for \"sodium chloride chemotaxis defective\" (WBPhenotype:0001084) (WS193 OBO and WS200 site) AND has term name \"pos body wall contraction defect\" (dump_phenotype_ace.pl)" ; owl:deprecated true . obo:WBPhenotype_0000996 obo:IAO_0000115 "Animals exhibit defects in the expulsion of gut contents. In C. elegans, this refers to the final step of the defecation cycle in which the intestinal muscle and anal depressor contractions further pressurize intestinal contents and open the anus to permit expulsion." ; oboInOwl:hasBroadSynonym "Emc", "Exp" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000996" ; a owl:Class ; rdfs:label "expulsion defective" ; rdfs:subClassOf obo:WBPhenotype_0000205 . obo:WBPhenotype_0000997 obo:IAO_0000115 "Animals tend to track and stay within low temperature environments." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000997" ; a owl:Class ; rdfs:label "cryophilic" ; rdfs:subClassOf obo:WBPhenotype_0000478 . obo:WBPhenotype_0000998 obo:IAO_0000115 "Animals tend to track and stay within high temperature environments." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000998" ; a owl:Class ; rdfs:label "thermophilic" ; rdfs:subClassOf obo:WBPhenotype_0000478 . obo:WBPhenotype_0000999 obo:IAO_0000115 "The responses of an animal towards temperature are not influenced by its cultivation temperature." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0000999" ; a owl:Class ; rdfs:label "athermotactic" ; rdfs:subClassOf obo:WBPhenotype_0000478 . obo:WBPhenotype_0001000 obo:IAO_0000115 "Any variation in the behavior characteristic during certain developmental stage(s) compared to control." ; oboInOwl:hasNarrowSynonym "developmental behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001000" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "developmental behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000525 . obo:WBPhenotype_0001001 obo:IAO_0000115 "Variations in the specific actions or reactions of dauer stage animals in response to external or internal stimuli compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "dauer behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001001" ; a owl:Class ; rdfs:label "dauer behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000819 . obo:WBPhenotype_0001002 obo:IAO_0000115 "Variations in the specific actions or reactions of the head muscles in response to external or internal stimuli compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "head muscle behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001002" ; a owl:Class ; rdfs:label "head muscle behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000595 . obo:WBPhenotype_0001003 obo:IAO_0000115 "Animals die at the L4 stage of the life cycle." ; oboInOwl:hasBroadSynonym "Let", "Lvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001003" ; a owl:Class ; rdfs:label "L4 lethal" ; rdfs:subClassOf obo:WBPhenotype_0000058, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000038 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000038 ] ) ] ] . obo:WBPhenotype_0001004 obo:IAO_0000115 "Any variation in the relaxation of pharyngeal muscles after contraction events compared to control." ; oboInOwl:hasNarrowSynonym "pharyngeal relaxation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001004" ; a owl:Class ; rdfs:label "pharyngeal relaxation variant" ; rdfs:subClassOf obo:WBPhenotype_0000634 . obo:WBPhenotype_0001005 obo:IAO_0000115 "Variations in the spontaneous or induced backward crawling locomotion of an animal compared to control." ; oboInOwl:hasNarrowSynonym "backward locomotion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001005" ; a owl:Class ; rdfs:label "backward locomotion variant" ; rdfs:subClassOf obo:WBPhenotype_0002320, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043057 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043057 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001006 obo:IAO_0000115 "The number of coordinated contraction-relaxation cycles (pumps) exhibited by the pharyngeal muscle deviates from that observed for control animals." ; oboInOwl:hasNarrowSynonym "pharyngeal pumping rate abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "feeding rate dynamics abnormal", "pumping rate dynamics abnormal" ; oboInOwl:id "WBPhenotype:0001006" ; a owl:Class ; rdfs:label "pharyngeal pumping rate variant" ; rdfs:subClassOf obo:WBPhenotype_0000634, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000161 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000161 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001007 obo:IAO_0000115 "Unclassified abnormality in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb", "Oth" ; oboInOwl:hasNarrowSynonym "other abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001007" ; a owl:Class ; rdfs:label "other abnormality early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100 . obo:WBPhenotype_0001008 obo:IAO_0000115 "Variations in the progression of a set of interacting or interdependent entities forming the male nervous system over time from an initial condition to a later condition compared to control animals. The nervous system is involved in the coordination and control of bodily activities and the interpretation of information from the senses." ; oboInOwl:hasNarrowSynonym "male nervous system development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001008" ; a owl:Class ; rdfs:label "male nervous system development variant" ; rdfs:subClassOf obo:WBPhenotype_0000623 . obo:WBPhenotype_0001009 obo:IAO_0000115 "Animals exhibit variations in the accumulation or expression of biochromes or any other substances that alter transparency/translucency of a particular developmental stage of the amimal compared to control animals." ; oboInOwl:hasNarrowSynonym "developmental pigmentation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001009" ; a owl:Class ; rdfs:label "developmental pigmentation variant" ; rdfs:subClassOf obo:WBPhenotype_0000519, obo:WBPhenotype_0000527, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048066 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048066 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001010 obo:IAO_0000115 "Animals appear unusually transparent when compared to control." ; oboInOwl:hasBroadSynonym "Clr" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001010" ; a owl:Class ; rdfs:label "clear" ; rdfs:subClassOf obo:WBPhenotype_0000527 . obo:WBPhenotype_0001011 obo:IAO_0000115 "Population of unhatched eggs exhibit a complex combination of defects that do not match other class definitions." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001011" ; a owl:Class ; rdfs:label "complex phenotype early emb" ; rdfs:subClassOf obo:WBPhenotype_0001007 . obo:WBPhenotype_0001012 obo:IAO_0000115 "Animals exhibit variations in their response to disease causing agents, compared to control. Pathogen response includes prevention, damage control and recovery from the infection caused by the attack." ; oboInOwl:hasNarrowSynonym "bacterial load variant", "organism pathogen response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001012" ; a owl:Class ; rdfs:label "organism pathogen response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0098542 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0098542 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001013 obo:IAO_0000115 "Animals are more prone to infection compared to control." ; oboInOwl:hasBroadSynonym "Esp" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "enhanced susceptibility to pathogens" ; oboInOwl:id "WBPhenotype:0001013" ; a owl:Class ; rdfs:label "pathogen susceptibility increased" ; rdfs:subClassOf obo:WBPhenotype_0001012 . obo:WBPhenotype_0001014 obo:IAO_0000115 "Animals are less prone to infection compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "pathogen susceptibility decreased" ; oboInOwl:id "WBPhenotype:0001014" ; a owl:Class ; rdfs:label "pathogen resistance increased" ; rdfs:subClassOf obo:WBPhenotype_0001012 . obo:WBPhenotype_0001015 obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during any development stages compared to control animals." ; oboInOwl:hasNarrowSynonym "developmental growth abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001015" ; a owl:Class ; rdfs:label "developmental growth variant" ; rdfs:subClassOf obo:WBPhenotype_0000030, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048589 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048589 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001016 obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the larval stages compared to control animals." ; oboInOwl:hasNarrowSynonym "larval growth abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001016" ; a owl:Class ; rdfs:label "larval growth variant" ; rdfs:subClassOf obo:WBPhenotype_0001015 . obo:WBPhenotype_0001017 obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the adult stage compared to control animals." ; oboInOwl:hasNarrowSynonym "adult growth abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001017" ; a owl:Class ; rdfs:label "adult growth variant" ; rdfs:subClassOf obo:WBPhenotype_0001015, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040007 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000041 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040007 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000041 ] ) ] ] . obo:WBPhenotype_0001018 obo:IAO_0000115 "Any variation that disrupts the cytoplasmic division of a cell during embryonic development compared to control." ; oboInOwl:hasBroadSynonym "Cyk" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001018" ; a owl:Class ; rdfs:label "cytokinesis variant emb" ; rdfs:subClassOf obo:WBPhenotype_0000050, obo:WBPhenotype_0002408 . obo:WBPhenotype_0001019 obo:IAO_0000115 "Animals arrest during the stage between early and late larval development. In C. elegans, mid larval arrest occurs during the L2 to L3 stages of development." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001019" ; a owl:Class ; rdfs:label "mid larval arrest" ; rdfs:subClassOf obo:WBPhenotype_0000059, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0002164 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000027 ] ) ] ] . obo:WBPhenotype_0001020 obo:IAO_0000115 "Animals die during the final stages of embryogenesis. In C. elegans, this lethality refers to death during the last (3-fold) stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation." ; oboInOwl:hasBroadSynonym "Emb", "Led" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001020" ; a owl:Class ; rdfs:label "embryonic lethal late emb" ; rdfs:subClassOf obo:WBPhenotype_0000050, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000021 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000021 ] ) ] ] . obo:WBPhenotype_0001021 obo:IAO_0000115 "Genetically male animals exhibit deviations in the sexual program specific to males. In C. elegans, this often refers to XO animals being transformed into fertile hermaphrodites." ; oboInOwl:hasBroadSynonym "Her" ; oboInOwl:hasNarrowSynonym "male sexual development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001021" ; a owl:Class ; rdfs:label "male sexual development variant" ; rdfs:subClassOf obo:WBPhenotype_0000822 . obo:WBPhenotype_0001022 obo:IAO_0000115 "Genetically hermaphrodite animals exhibit deviations in the sexual program specific to hermaphrodites. In C. elegans, this refers to XX animals that develop as males or intersexuals instead of self-fertile hermaphrodites." ; oboInOwl:hasNarrowSynonym "hermaphrodite sexual development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001022" ; a owl:Class ; rdfs:label "hermaphrodite sexual development variant" ; rdfs:subClassOf obo:WBPhenotype_0000822 . obo:WBPhenotype_0001023 obo:IAO_0000115 "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as one sex or the other in the population, from that observed for control animals." ; oboInOwl:hasNarrowSynonym "sexually dimorphic morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001023" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "sexually dimorphic morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000535 . obo:WBPhenotype_0001024 obo:IAO_0000115 "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a male in the population, from that observed for control males." ; oboInOwl:hasNarrowSynonym "male morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001024" ; a owl:Class ; rdfs:label "male morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001023, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001025 obo:IAO_0000115 "Animals exhibit variations in the outcome of morphogenic processes required for formation or proper placement of sex-specific structures that distinguish the animal as a hermaphrodite in the population, from that observed for control hermaphrodites." ; oboInOwl:hasNarrowSynonym "hermaphrodite morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001025" ; a owl:Class ; rdfs:label "hermaphrodite morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001023, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007849 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007849 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001026 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the membrane enclosed organelle which contains most of the cell's genetic material during the early embryonic stage compared to control animals (Wormatlas)." ; oboInOwl:hasBroadSynonym "Emb", "Nmo" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001026" ; a owl:Class ; rdfs:label "nuclear morphology variation early emb" ; rdfs:subClassOf obo:WBPhenotype_0001028, obo:WBPhenotype_0001035, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001027 obo:IAO_0000115 "Embryos show defects in the placement of the nucleus to a specific location within the cell." ; oboInOwl:hasBroadSynonym "Emb", "Npo" ; oboInOwl:hasNarrowSynonym "nuclear position abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001027" ; a owl:Class ; rdfs:label "nuclear position defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000511, obo:WBPhenotype_0001138 . obo:WBPhenotype_0001028 obo:IAO_0000115 "The morphological appearance of nuclei differs from control animals." ; oboInOwl:hasNarrowSynonym "nuclear appearance abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "nuclear morphology variant" ; oboInOwl:id "WBPhenotype:0001028" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "nuclear appearance variant" ; rdfs:subClassOf obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001029 obo:IAO_0000115 "Animals exhibit an uneven distribution of biochromes or any other substances that cause disparate transparency/translucency compared to control animals." ; oboInOwl:hasBroadSynonym "Pch" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001029" ; a owl:Class ; rdfs:label "patchy coloration" ; rdfs:subClassOf obo:WBPhenotype_0000527 . obo:WBPhenotype_0001030 obo:IAO_0000115 "Any deficiency in the lipid bilayer, the equivalent of the nuclear envelope, that surrounds each pronucleus within gametes and within the early zygote after pronuclear reformation (Wormatlas)." ; oboInOwl:hasBroadSynonym "Emb", "Pna" ; oboInOwl:hasNarrowSynonym "pronuclear envelope abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001030" ; a owl:Class ; rdfs:label "pronuclear envelope defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001151 . obo:WBPhenotype_0001031 obo:IAO_0000115 "Any variation in the movement/fusion of pronuclei in the fertilized oocyte compared to control. For example, lack of male pronuclear migration, female pronuclear migration variable, sometimes multiple female pronuclei, no or small spindle." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001031" ; a owl:Class ; rdfs:label "pronuclear migration reduced early emb" ; rdfs:subClassOf obo:WBPhenotype_0000511, obo:WBPhenotype_0001152, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035046 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035046 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001032 obo:IAO_0000115 "Variations in the specific actions or reactions of a larvae in response to external or internal stimuli compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "larval behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001032" ; a owl:Class ; rdfs:label "larval behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000819, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030537 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030537 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001033 obo:IAO_0000115 "Any variation in the spatial pattern of proliferation and differentiation in the germ line compared to control. In C. elegans, this refers to an ectopic mass of proliferating germ cells that occupies the proximal adult germ line, a region normally occupied by gametes." ; oboInOwl:hasBroadSynonym "Pro" ; oboInOwl:hasNarrowSynonym "proximal germ cell proliferation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001033" ; a owl:Class ; rdfs:label "proximal germ cell proliferation variant" ; rdfs:subClassOf obo:WBPhenotype_0001215 . obo:WBPhenotype_0001034 obo:IAO_0000115 "The morphology of pronuclei and nuclei are defective in the early embryo. In C. elegans, this defect is often characterized by pronuclei and nuclei that are small or missing altogether and are often accompanied by spindle defects." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pronuclear nuclear appearance abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001034" ; a owl:Class ; rdfs:label "pronuclear nuclear appearance defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001374 . obo:WBPhenotype_0001035 obo:IAO_0000115 "The size, number and organization of the components of the nuclei in the early embryo deviate from control . In C. elegans, this is characterized by nuclei that are completely missing or are significantly smaller than normal; often accompanied by spindle and cytokinesis defects." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "nuclear appearance number abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "nucleus abnormal emb" ; oboInOwl:id "WBPhenotype:0001035" ; a owl:Class ; rdfs:label "nuclear appearance number defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000770, obo:WBPhenotype_0001138 . obo:WBPhenotype_0001036 obo:IAO_0000115 "Any variation that compromises the reproductive ability of an F1 generation animal." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001036" ; a owl:Class ; rdfs:label "sterile F1" ; rdfs:subClassOf obo:WBPhenotype_0001037 . obo:WBPhenotype_0001037 obo:IAO_0000115 "Any variation that compromises the reproductive ability of the progeny of an animal." ; oboInOwl:hasBroadSynonym "Stp" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001037" ; a owl:Class ; rdfs:label "sterile progeny" ; rdfs:subClassOf obo:WBPhenotype_0000069, obo:WBPhenotype_0000688 . obo:WBPhenotype_0001038 obo:IAO_0000115 "Germ cells do not exit the mitotic cycle, resulting in a expansion of the unspecialized germ cell population compared to control." ; oboInOwl:hasBroadSynonym "Tum" ; oboInOwl:hasExactSynonym "tumorous germ line" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001038" ; a owl:Class ; rdfs:label "tumorous germline" ; rdfs:subClassOf obo:WBPhenotype_0000823, obo:WBPhenotype_0002175 . obo:WBPhenotype_0001039 obo:IAO_0000115 "Variations in the processes that regulate the change (increase) in size or mass of an integrated living unit (a cell, tissue, organ or organism) during the embryonic stage compared to control animals." ; oboInOwl:hasNarrowSynonym "embryonic growth abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001039" ; a owl:Class ; rdfs:label "embryonic growth variant" ; rdfs:subClassOf obo:WBPhenotype_0001015 . obo:WBPhenotype_0001040 obo:IAO_0000115 "Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus, compared to control." ; oboInOwl:hasNarrowSynonym "chemosensory response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001040" ; a owl:Class ; rdfs:label "chemosensory response variant" ; rdfs:subClassOf obo:WBPhenotype_0000523, obo:WBPhenotype_0001049 . obo:WBPhenotype_0001041 obo:IAO_0000115 "Animals exhibit defects in the progression of meiosis which ultimately result in embryonic lethality." ; oboInOwl:hasBroadSynonym "Emb", "Mei" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001041" ; a owl:Class ; rdfs:label "meiosis defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000775, obo:WBPhenotype_0001100 . obo:WBPhenotype_0001042 obo:IAO_0000115 "Neurons show impaired ability in the detection, transmission, coordination or their response to information about an animal's internal and external environments." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001042" ; a owl:Class ; rdfs:label "neuron function reduced" ; rdfs:subClassOf obo:WBPhenotype_0002552, obo:WBPhenotype_0002563, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001624 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001624 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001043 obo:IAO_0000115 "Embryos do not enter or take longer to enter first interphase compared to control." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001043" ; a owl:Class ; rdfs:label "interphase entry defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000740, obo:WBPhenotype_0001100 . obo:WBPhenotype_0001044 obo:IAO_0000115 "Little/no cortical ruffling or pseudocleavage furrow, or excessive cortical activity. In C. elegans, this is often characterized at the two-cell stage." ; oboInOwl:hasBroadSynonym "Cpa", "Emb" ; oboInOwl:hasNarrowSynonym "cortical dynamics abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001044" ; a owl:Class ; rdfs:label "cortical dynamics defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000764, obo:WBPhenotype_0001100 . obo:WBPhenotype_0001045 obo:IAO_0000115 "Pharyngeal pumping contractions are brief and occur arhythmically in response to stimulus compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001045" ; a owl:Class ; rdfs:label "sporadic pumping" ; rdfs:subClassOf obo:WBPhenotype_0000019 . obo:WBPhenotype_0001046 obo:IAO_0000115 "Any variations associated with the characteristic morphology of the pharyngeal muscle such as shape, birefringence etc compared to control." ; oboInOwl:hasNarrowSynonym "pharyngeal muscle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001046" ; a owl:Class ; rdfs:label "pharyngeal muscle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000923, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005451 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005451 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001047 obo:IAO_0000115 "Animals exhibit variations in the movement towards typically attractive water-soluble chemicals compared to control." ; oboInOwl:hasNarrowSynonym "aqueous positive chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "water soluble chemotaxis abnormal" ; oboInOwl:id "WBPhenotype:0001047" ; a owl:Class ; rdfs:label "aqueous positive chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000635, obo:WBPhenotype_0001443 . obo:WBPhenotype_0001048 obo:IAO_0000115 "Animals exhibit variations in the chemosensory response to volatile organic compounds compared to control." ; oboInOwl:hasBroadSynonym "Odr" ; oboInOwl:hasNarrowSynonym "odorant chemosensory response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "volatile chemosensory response abnormal" ; oboInOwl:id "WBPhenotype:0001048" ; a owl:Class ; rdfs:label "odorant chemosensory response variant" ; rdfs:subClassOf obo:WBPhenotype_0001040, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042048 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042048 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001049 obo:IAO_0000115 "Variations in behavior that is dependent upon the sensation of chemicals, compared to control." ; oboInOwl:hasNarrowSynonym "chemosensory behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001049" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "chemosensory behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007635 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007635 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001050 obo:IAO_0000115 "Animals exhibit variations in any of a series of events in which an organism receives a sensory chemical stimulus, converts it to a molecular signal, and recognizes and characterizes the signal, compared to control." ; oboInOwl:hasNarrowSynonym "chemosensation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001050" ; a owl:Class ; rdfs:label "chemosensation variant" ; rdfs:subClassOf obo:WBPhenotype_0001049 . obo:WBPhenotype_0001051 obo:IAO_0000115 "Animals exhibit variations in the characteristic movement towards typically attractive cations compared to control." ; oboInOwl:hasNarrowSynonym "cation positive chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001051" ; a owl:Class ; rdfs:label "cation positive chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001047 . obo:WBPhenotype_0001052 obo:IAO_0000115 "Animals exhibit variations in the characteristic movement towards typically attractive anions compared to control." ; oboInOwl:hasNarrowSynonym "anion positive chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001052" ; a owl:Class ; rdfs:label "anion positive chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001047 . obo:WBPhenotype_0001053 obo:IAO_0000115 "Animals exhibit variations in the characteristic movement towards cyclic nucleotides compared to control." ; oboInOwl:hasNarrowSynonym "cyclic nucleotide positive chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001053" ; a owl:Class ; rdfs:label "cyclic nucleotide positive chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001047 . obo:WBPhenotype_0001054 obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to cGMP. In C. elegans, this is characterized by the failure to move towards cGMP." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001054" ; a owl:Class ; rdfs:label "cGMP chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001464, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_27682 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_27682 ] ) ] ] . obo:WBPhenotype_0001055 obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to bromide. In C. elegans, this is characterized by the failure to move towards bromide." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001055" ; a owl:Class ; rdfs:label "bromide chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001439, obo:WBPhenotype_0001457, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_15858 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_15858 ] ) ] ] . obo:WBPhenotype_0001056 obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to iodide. In C. elegans, this is characterized by the failure to move towards iodide." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001056" ; a owl:Class ; rdfs:label "iodide chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001439, obo:WBPhenotype_0001459, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_16382 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_16382 ] ) ] ] . obo:WBPhenotype_0001057 obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to lithium. In C. elegans, this is characterized by the failure to move towards lithium." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001057" ; a owl:Class ; rdfs:label "lithium chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001440, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_30145 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_30145 ] ) ] ] . obo:WBPhenotype_0001058 obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to potassium. In C. elegans, this is characterized by the failure of the animals to move towards potassium." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001058" ; a owl:Class ; rdfs:label "potassium chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001440, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_26216 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_26216 ] ) ] ] . obo:WBPhenotype_0001059 obo:IAO_0000115 "Animals fail to exhibit the same taxis behavior as control animals in response to magnesium. In C. elegans, this is characterized by the failure to move towards magnesium." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001059" ; a owl:Class ; rdfs:label "magnesium chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001440, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_25107 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_25107 ] ) ] ] . obo:WBPhenotype_0001060 obo:IAO_0000115 "In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWC compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "AWC volatile chemotaxis defective" ; oboInOwl:id "WBPhenotype:0001060" ; a owl:Class ; rdfs:label "AWC odorant chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438 . obo:WBPhenotype_0001061 obo:IAO_0000115 "In C. elegans, this is characterized by the failure to move towards typically attractive volatile organic molecules sensed by the AWA compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "AWA volatile chemotaxis defective" ; oboInOwl:id "WBPhenotype:0001061" ; a owl:Class ; rdfs:label "AWA odorant chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438 . obo:WBPhenotype_0001062 obo:IAO_0000115 "In C. elegans, movement and elongation stop nearly simultaneously soon after the twofold stage of elongation. However, mutant embryos twitch at the one-and-a-half-fold stage of elongation, like control animals, and move as well as control animals at the two- fold stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001062" ; a owl:Class ; rdfs:label "late paralysis arrested elongation two fold" ; rdfs:subClassOf obo:WBPhenotype_0000749 . obo:WBPhenotype_0001063 obo:IAO_0000115 "Fluctuation pattern between inactive, active, and egg-laying states is atypical, based on the analysis of the distribution of the log intervals of egg-laying events compared to control." ; oboInOwl:hasNarrowSynonym "egg laying phases abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001063" ; a owl:Class ; rdfs:label "egg laying phases variant" ; rdfs:subClassOf obo:WBPhenotype_0000272 . obo:WBPhenotype_0001064 obo:IAO_0000115 "Animals display uncharacteristically long periods during which they do not lay eggs compared to control, usually based on the analysis of the distribution of the log intervals of egg-laying events. In C. elegans, long inactive phases can be observed in HSN-ablated and serotonin-deficient animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001064" ; a owl:Class ; rdfs:label "inactive phase long" ; rdfs:subClassOf obo:WBPhenotype_0000006, obo:WBPhenotype_0001066 . obo:WBPhenotype_0001065 obo:IAO_0000115 "Fewer egg-laying events occur within the active phase of egg laying, based on the analysis of the distribution of the log intervals of egg-laying events, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001065" ; a owl:Class ; rdfs:label "fewer egg laying events during active" ; rdfs:subClassOf obo:WBPhenotype_0000006, obo:WBPhenotype_0001067 . obo:WBPhenotype_0001066 obo:IAO_0000115 "The period during which the animal is less likely to lay eggs is not typical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ; oboInOwl:hasNarrowSynonym "inactive phase abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001066" ; a owl:Class ; rdfs:label "inactive phase variant" ; rdfs:subClassOf obo:WBPhenotype_0001063 . obo:WBPhenotype_0001067 obo:IAO_0000115 "The active phase of egg-laying, the period during which animals are more likely to display multiple egg-laying events, is atypical compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ; oboInOwl:hasNarrowSynonym "active phase abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001067" ; a owl:Class ; rdfs:label "active phase variant" ; rdfs:subClassOf obo:WBPhenotype_0001063 . obo:WBPhenotype_0001068 obo:IAO_0000115 "Animals are not induced to lay eggs in reponse to exogenous serotonin. Serotonin stimulates egg-laying in C. elegans." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001068" ; a owl:Class ; rdfs:label "egg laying serotonin resistant" ; rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001629, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001552 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001552 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] . obo:WBPhenotype_0001069 obo:IAO_0000115 "More eggs are laid during the active phase compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001069" ; a owl:Class ; rdfs:label "increased egg laying events during active" ; rdfs:subClassOf obo:WBPhenotype_0001067 . obo:WBPhenotype_0001070 obo:IAO_0000115 "The period during which a worm usually does not lay eggs is short compared with control animals, based on the analysis of the distribution of the log intervals of egg-laying events." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001070" ; a owl:Class ; rdfs:label "inactive phase short" ; rdfs:subClassOf obo:WBPhenotype_0001066 . obo:WBPhenotype_0001071 obo:IAO_0000115 "Activation of the active phase of egg laying is defective, leading to an abnormally long inactive phase, based on the analysis of the distribution of the log intervals of egg-laying events." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001071" ; a owl:Class ; rdfs:label "active phase switch defective" ; rdfs:subClassOf obo:WBPhenotype_0001064 . obo:WBPhenotype_0001072 obo:IAO_0000115 "Any variation in the state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to a food stimulus, compared to control." ; oboInOwl:hasNarrowSynonym "response to food abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001072" ; a owl:Class ; rdfs:label "response to food variant" ; rdfs:subClassOf obo:WBPhenotype_0000523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032094 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0032094 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001073 obo:IAO_0000115 "Animals exhibit variations in egg-laying behavior in response to food compared to control. In C. elegans, well-fed animals lay more eggs compared with starved animals." ; oboInOwl:hasNarrowSynonym "egg laying response to food abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001073" ; a owl:Class ; rdfs:label "egg laying response to food variant" ; rdfs:subClassOf obo:WBPhenotype_0000640, obo:WBPhenotype_0001072, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001457 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_33290 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001457 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_33290 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001074 obo:IAO_0000115 "The vulval muscle does not respond to serotonin in the same manner as control animals. This phenotype is often assayed by imaging of calcium transients in response to serotonin." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001074" ; a owl:Class ; rdfs:label "vulval muscle unresponsive to serotonin" ; rdfs:subClassOf obo:WBPhenotype_0001068, obo:WBPhenotype_0001076, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000488 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005821 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000488 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005821 ] ) ] ] . obo:WBPhenotype_0001075 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the vulva muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "vulval muscle physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001075" ; a owl:Class ; rdfs:label "vulval muscle physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000613, obo:WBPhenotype_0000929, obo:WBPhenotype_0000990, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005821 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005821 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001076 obo:IAO_0000115 "Variations in the chemical reactions and pathways involved in the maintenance of an internal equilibrium within the vulval muscles compared to control." ; oboInOwl:hasNarrowSynonym "vulval muscle homeostasis metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001076" ; a owl:Class ; rdfs:label "vulval muscle homeostasis metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0001075 . obo:WBPhenotype_0001077 obo:IAO_0000115 "Karyomeres in AB or P1 often accompanied by weak/thin wobbly spindle." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001077" ; a owl:Class ; rdfs:label "chromosome segregation variant karyomeres early emb" ; rdfs:subClassOf obo:WBPhenotype_0000773, obo:WBPhenotype_0001100 . obo:WBPhenotype_0001078 obo:IAO_0000115 "Cytokinesis is abnormal in the first or second stages of cell division." ; oboInOwl:hasBroadSynonym "Cyk", "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001078" ; a owl:Class ; rdfs:label "cytokinesis defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001018, obo:WBPhenotype_0001100 . obo:WBPhenotype_0001079 obo:IAO_0000115 "Cytoplasmic movements are atypical." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001079" ; a owl:Class ; rdfs:label "cytoplasmic dynamics defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000360, obo:WBPhenotype_0000769 . obo:WBPhenotype_0001080 obo:IAO_0000115 "Excessive shaking and movements are seen in the cell membrane or cytoplasm of one-cell or two-cell embryos." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001080" ; a owl:Class ; rdfs:label "excessive blebbing early emb" ; rdfs:subClassOf obo:WBPhenotype_0001079 . obo:WBPhenotype_0001081 obo:IAO_0000115 "Morphology of the cytoplasm differs from control animals." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001081" ; a owl:Class ; rdfs:label "cytoplasmic morphology defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000769 . obo:WBPhenotype_0001082 obo:IAO_0000115 "Abnormally large granules are observed in the cytoplasm of P0." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001082" ; a owl:Class ; rdfs:label "large cytoplasmic granules early emb" ; rdfs:subClassOf obo:WBPhenotype_0001081 . obo:WBPhenotype_0001083 obo:IAO_0000115 "Multiple vesicles, vacuoles, or cavities are seen during early embryogenesis." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001083" ; a owl:Class ; rdfs:label "multiple cytoplasmic cavities early emb" ; rdfs:subClassOf obo:WBPhenotype_0001081 . obo:WBPhenotype_0001084 obo:IAO_0000115 "Failure to execute characteristic response to sodium chloride compared to control. In C. elegans, animals move towards attractive concentrations of sodium chloride." ; oboInOwl:hasExactSynonym "NaCl chemotaxis defective" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001084" ; a owl:Class ; rdfs:label "sodium chloride chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001462, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_26710 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_26710 ] ) ] ] . obo:WBPhenotype_0001085 obo:IAO_0000115 "Failure to execute characteristic response to butanone compared to control. In C. elegans, animals move towards typically attractive concentrations of butanone." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001085" ; a owl:Class ; rdfs:label "butanone chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001469, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_22951 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_22951 ] ) ] ] . obo:WBPhenotype_0001086 obo:IAO_0000115 "Failure to execute characteristic response to trimethylthiazole compared to control. In C. elegans, animals move towards typically attractive concentrations of trimethylthiazole." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001086" ; a owl:Class ; rdfs:label "trimethylthiazole chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001475 . obo:WBPhenotype_0001087 obo:IAO_0000115 "Failure to execute characteristic response to acetone compared to control. In C. elegans, animals move towards typically attractive concentrations of acetone." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001087" ; a owl:Class ; rdfs:label "acetone chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001465, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_15347 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_15347 ] ) ] ] . obo:WBPhenotype_0001088 obo:IAO_0000115 "Failure to execute characteristic response to pentanol compared to control. In C. elegans, animals move towards typically attractive concentrations of pentanol." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001088" ; a owl:Class ; rdfs:label "pentanol chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001473 . obo:WBPhenotype_0001089 obo:IAO_0000115 "Failure to execute characteristic response to hexanol compared to control. In C. elegans, animals move towards typically attractive concentrations of hexanol." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001089" ; a owl:Class ; rdfs:label "hexanol chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001438, obo:WBPhenotype_0001471 . obo:WBPhenotype_0001090 obo:IAO_0000115 "Animals are not able to survive at temperatures above standard cultivation temperatures to the same extent as control animals." ; oboInOwl:hasNarrowSynonym "intrinsic thermotolerance reduced" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001090" ; a owl:Class ; rdfs:label "thermotolerance reduced" ; rdfs:subClassOf obo:WBPhenotype_0000146 . obo:WBPhenotype_0001091 obo:IAO_0000115 "Animals exhibit variations in the elimination of fecal matter during the larval stage compared to control animals." ; oboInOwl:hasNarrowSynonym "larval defecation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001091" ; a owl:Class ; rdfs:label "larval defecation variant" ; rdfs:subClassOf obo:WBPhenotype_0000650 . obo:WBPhenotype_0001092 obo:IAO_0000115 "Animals fail to expel fecal matter during the larval stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001092" ; a owl:Class ; rdfs:label "larval defecation defect" ; rdfs:subClassOf obo:WBPhenotype_0001091 . obo:WBPhenotype_0001093 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the intestine to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "intestinal physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001093" ; a owl:Class ; rdfs:label "intestinal physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000606, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005772 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005772 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001094 obo:IAO_0000115 "OBSOLETE. Organismal response to NaCl differs from control animals." ; oboInOwl:consider obo:WBPhenotype_0000523 ; oboInOwl:hasNarrowSynonym "NaCl response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001094" ; a owl:Class ; rdfs:label "obsolete NaCl response variant" ; owl:deprecated true . obo:WBPhenotype_0001095 obo:IAO_0000115 "Animals respond to sodium chloride at a lower concentration or a shorter exposure compared to control animals. In C. elegans, this is often assayed through generation time and progeny number." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001095" ; a owl:Class ; rdfs:label "organism high sodium chloride hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000876, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_26710 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_26710 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001096 obo:IAO_0000115 "Large protrusion at the normal position of the vulva, as seen in C. elegans lin-12 null animals." ; oboInOwl:hasNarrowSynonym "ventral protrusion" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001096" ; a owl:Class ; rdfs:label "protrusion at vulval region" ; rdfs:subClassOf obo:WBPhenotype_0000695 . obo:WBPhenotype_0001097 obo:IAO_0000115 "Unspecialized male germ cells (spermatocytes) prematurely acquire the specialized properties of functional sperm." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001097" ; a owl:Class ; rdfs:label "premature spermatocyte germ cell differentiation" ; rdfs:subClassOf obo:WBPhenotype_0000670 . obo:WBPhenotype_0001098 obo:IAO_0000115 "Animals lack the passage connecting the posterior intestine to the rectal valve." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001098" ; a owl:Class ; rdfs:comment "WBbt:0005773." ; rdfs:label "no rectum" ; rdfs:subClassOf obo:WBPhenotype_0000910, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005773 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005773 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001099 obo:IAO_0000115 "The extreme anterior part of the body appears distorted, usually due to uncharacteristic winding." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001099" ; a owl:Class ; rdfs:label "nose twisted" ; rdfs:subClassOf obo:WBPhenotype_0000321 . obo:WBPhenotype_0001100 obo:IAO_0000115 "Animal dies prior to the gastrulation stage of embryogenesis." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001100" ; a owl:Class ; rdfs:label "early embryonic lethal" ; rdfs:subClassOf obo:WBPhenotype_0000050, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001101 obo:IAO_0000115 "Characteristic response to drugs with respect to egg-laying behavior varies compared to control." ; oboInOwl:hasNarrowSynonym "egg laying response to drug abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001101" ; a owl:Class ; rdfs:label "egg laying response to drug variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0000640 . obo:WBPhenotype_0001102 obo:IAO_0000115 "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a mitotic cell cycle." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001102" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "mitotic spindle defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000759 . obo:WBPhenotype_0001103 obo:IAO_0000115 "Early embryos lack the array of microtubules and associated molecules that form between opposite poles of a eukaryotic cell during mitosis or meiosis." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001103" ; a owl:Class ; rdfs:label "spindle absent early emb" ; rdfs:subClassOf obo:WBPhenotype_0001102, obo:WBPhenotype_0002418, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001104 obo:IAO_0000115 "No mitotic spindle is seen in P0." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001104" ; a owl:Class ; rdfs:label "P0 spindle absent early emb" ; rdfs:subClassOf obo:WBPhenotype_0001103, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004422 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002000 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004422 ] ) ] ] . obo:WBPhenotype_0001105 obo:IAO_0000115 "Altered P0 spindle placement causes either a symmetric first division, a division in which P1 is larger than AB, or a division in which the asymmetry is exaggerated such that AB is much larger than normal." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "P0 spindle position phenotype" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001105" ; a owl:Class ; rdfs:label "P0 spindle position abnormal" ; rdfs:subClassOf obo:WBPhenotype_0000762, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0072686 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:WBbt_0004422 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0072686 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:WBbt_0004422 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001106 obo:IAO_0000115 "The orientation of the spindle is aberrant in either the AB or the P1 cell." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001106" ; a owl:Class ; rdfs:label "spindle orientation variant AB or P1 early emb" ; rdfs:subClassOf obo:WBPhenotype_0000760 . obo:WBPhenotype_0001107 obo:IAO_0000115 "Rotation of the embryonic spindle is aberrant." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001107" ; a owl:Class ; rdfs:label "spindle rotation defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001102, obo:WBPhenotype_0002417, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001599 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001599 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001108 obo:IAO_0000115 "P0 spindle fails to rotate and extends perpendicular to the long axis of the embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001108" ; a owl:Class ; rdfs:label "P0 spindle rotation failure early emb" ; rdfs:subClassOf obo:WBPhenotype_0001107 . obo:WBPhenotype_0001109 obo:IAO_0000115 "P0 spindle rotates late in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001109" ; a owl:Class ; rdfs:label "P0 spindle rotation delayed early emb" ; rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0001107 . obo:WBPhenotype_0001110 obo:IAO_0000115 "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "aster abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001110" ; a owl:Class ; rdfs:label "aster defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002419 . obo:WBPhenotype_0001111 obo:IAO_0000115 "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the AB cell." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "aster AB abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001111" ; a owl:Class ; rdfs:label "aster AB defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001110 . obo:WBPhenotype_0001112 obo:IAO_0000115 "The morphology of the AB aster resembles that of the P1 aster in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001112" ; a owl:Class ; rdfs:label "aster AB resembles P1 aster early emb" ; rdfs:subClassOf obo:WBPhenotype_0001111 . obo:WBPhenotype_0001113 obo:IAO_0000115 "Early embryos exhibit defects in the array of microtubules emanating from a spindle pole that do not connect to kinetochores in the P1 cell." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "P1 aster abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001113" ; a owl:Class ; rdfs:label "P1 aster defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001110 . obo:WBPhenotype_0001114 obo:IAO_0000115 "The progression of biochemical and morphological processes that occur during successive replication or nuclear replication events is disrupted during the early embryonic stage." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001114" ; a owl:Class ; rdfs:label "cell cycle defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000740, obo:WBPhenotype_0001100 . obo:WBPhenotype_0001115 obo:IAO_0000115 "Cell cycle timing is abnormal during the first four cell divisions." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001115" ; a owl:Class ; rdfs:label "cell cycle timing defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001114 . obo:WBPhenotype_0001116 obo:IAO_0000115 "Absolute cell cycle timing during the first four cell divisions is aberrant." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "absolute cell cycle timing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001116" ; a owl:Class ; rdfs:label "absolute cell cycle timing defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001115 . obo:WBPhenotype_0001117 obo:IAO_0000115 "Cell-cell contacts are abnormal in the early embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001117" ; a owl:Class ; rdfs:label "cell cell contacts abnormal early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002404 . obo:WBPhenotype_0001118 obo:IAO_0000115 "Cell position is abnormal in the early embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001118" ; a owl:Class ; rdfs:label "cell position defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002402, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CL_0000000 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CL_0000000 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001119 obo:IAO_0000115 "Embryos take longer to divide during the first and second cell divisions." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001119" ; a owl:Class ; rdfs:label "cell cycle slow early emb" ; rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0001116, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051726 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051726 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001120 obo:IAO_0000115 "Relative cell cycle timing during the first four cell divisions is aberrant." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "relative cell cycle timing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001120" ; a owl:Class ; rdfs:label "relative cell cycle timing defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001115 . obo:WBPhenotype_0001121 obo:IAO_0000115 "Asynchrony of the second division is exaggerated and P1 divides more slowly than normal." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001121" ; a owl:Class ; rdfs:label "exaggerated asynchrony early emb" ; rdfs:subClassOf obo:WBPhenotype_0001120 . obo:WBPhenotype_0001122 obo:IAO_0000115 "P1 divides before AB." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001122" ; a owl:Class ; rdfs:label "reversed asynchrony early emb" ; rdfs:subClassOf obo:WBPhenotype_0001120 . obo:WBPhenotype_0001123 obo:IAO_0000115 "AB and P1 divide synchronously." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001123" ; a owl:Class ; rdfs:label "synchronous second division early emb" ; rdfs:subClassOf obo:WBPhenotype_0001120 . obo:WBPhenotype_0001124 obo:IAO_0000115 "EMS divides at the same time that ABa and ABp divide." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001124" ; a owl:Class ; rdfs:label "ABa ABp EMS synchronous division early emb" ; rdfs:subClassOf obo:WBPhenotype_0001120 . obo:WBPhenotype_0001125 obo:IAO_0000115 "P2 and EMS divide synchronously." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001125" ; a owl:Class ; rdfs:label "P2 EMS synchronous division early emb" ; rdfs:subClassOf obo:WBPhenotype_0001120 . obo:WBPhenotype_0001126 obo:IAO_0000115 "Aba, ABp, EMS, or P1 contacts fewer of its sister cells than in control embryos." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "cell cell contacts abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001126" ; a owl:Class ; rdfs:label "cell cell contacts abnormal in four cell embryo" ; rdfs:subClassOf obo:WBPhenotype_0001117 . obo:WBPhenotype_0001127 obo:IAO_0000115 "The EMS blastomere fails to extend anteriorly and make extensive contact (hug) with the ABa blastomere." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001127" ; a owl:Class ; rdfs:label "EMS anterior extension fails early emb" ; rdfs:subClassOf obo:WBPhenotype_0001118 . obo:WBPhenotype_0001128 obo:IAO_0000115 "EMS extends too far anteriorly at the four cell stage." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001128" ; a owl:Class ; rdfs:label "EMS anterior extension extreme early emb" ; rdfs:subClassOf obo:WBPhenotype_0001118 . obo:WBPhenotype_0001129 obo:IAO_0000115 "Embryos exhibit defects in the formation, maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001129" ; a owl:Class ; rdfs:label "cleavage furrow defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001078, obo:WBPhenotype_0002410, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0032154 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001453 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0032154 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001130 obo:IAO_0000115 "Cells of the embryo attempt to divide but fail to form two daughter cells." ; oboInOwl:hasBroadSynonym "Cyk", "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001130" ; a owl:Class ; rdfs:label "cytokinesis fails early emb" ; rdfs:subClassOf obo:WBPhenotype_0001078, obo:WBPhenotype_0002391, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000910 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000910 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001131 obo:IAO_0000115 "Once formed, the mitotic furrow can \"slide\"laterally." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001131" ; a owl:Class ; rdfs:label "loose mitotic furrow early emb" ; rdfs:subClassOf obo:WBPhenotype_0001129 . obo:WBPhenotype_0001132 obo:IAO_0000115 "One or more extra cleavage furrows are seen in one or more cells of a one-cell to four-cell embryo" ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001132" ; a owl:Class ; rdfs:label "extra cleavage furrow early emb" ; rdfs:subClassOf obo:WBPhenotype_0001129 . obo:WBPhenotype_0001133 obo:IAO_0000115 "The cell division axis is not normal." ; oboInOwl:hasNarrowSynonym "division axis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001133" ; a owl:Class ; rdfs:label "division axis defective" ; rdfs:subClassOf obo:WBPhenotype_0000746 . obo:WBPhenotype_0001134 obo:IAO_0000115 "ABa or ABp divide in the wrong orientation." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "Aba ABp division axis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001134" ; a owl:Class ; rdfs:label "Aba ABp division axis defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001133 . obo:WBPhenotype_0001135 obo:IAO_0000115 "Animals exhibit defects in the form, structure or composition of any of its parts during the early embryonic stage." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001135" ; a owl:Class ; rdfs:label "embryonic morphology defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0001136, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001136 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any of its parts during any developmental stage ranging from zygote formation to hatching compared to control." ; oboInOwl:hasNarrowSynonym "embryonic morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001136" ; a owl:Class ; rdfs:label "embryonic morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000037, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000003 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000003 ] ) ] ] . obo:WBPhenotype_0001137 obo:IAO_0000115 "Embryos are produced that are less than fifty percent of the size of control embryos." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001137" ; a owl:Class ; rdfs:label "embryos small early emb" ; rdfs:subClassOf obo:WBPhenotype_0000229, obo:WBPhenotype_0001135, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001138 obo:IAO_0000115 "Nucleus is abnormal in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "nucleus abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001138" ; a owl:Class ; rdfs:label "nucleus defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000764 . obo:WBPhenotype_0001139 obo:IAO_0000115 "Nuclear envelope does not reassemble properly." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "nuclear reassembly defective early emb" ; oboInOwl:id "WBPhenotype:0001139" ; a owl:Class ; rdfs:label "nuclear envelope assembly variant early emb" ; rdfs:subClassOf obo:WBPhenotype_0001138, obo:WBPhenotype_0002037 . obo:WBPhenotype_0001140 obo:IAO_0000115 "Any variation in the normal orderly movement of neurons from one site to another compared to control." ; oboInOwl:hasNarrowSynonym "neuron migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001140" ; a owl:Class ; rdfs:label "neuron migration variant" ; rdfs:subClassOf obo:WBPhenotype_0000594, obo:WBPhenotype_0000816, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0001764 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0001764 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001141 obo:IAO_0000115 "After division of either one-cell or two-cell embryos, the nuclei reappear next to the cell division remnant." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001141" ; a owl:Class ; rdfs:label "nucleus reforms cell division remnant early emb" ; rdfs:subClassOf obo:WBPhenotype_0001027 . obo:WBPhenotype_0001142 obo:IAO_0000115 "Nuclear number is abnormal in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001142" ; a owl:Class ; rdfs:label "nuclear number defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001035, obo:WBPhenotype_0001894, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001143 obo:IAO_0000115 "Embryos contain more than one nucleus per cell in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb", "Mul" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "karyomeres", "multiple nuclei in early embryo emb" ; oboInOwl:id "WBPhenotype:0001143" ; a owl:Class ; rdfs:label "multiple nuclei early emb" ; rdfs:subClassOf obo:WBPhenotype_0000746, obo:WBPhenotype_0001142, obo:WBPhenotype_0002413, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001144 obo:IAO_0000115 "Defects are either seen in the number or size of the polar bodies in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001144" ; a owl:Class ; rdfs:label "polar body number size early emb" ; rdfs:subClassOf obo:WBPhenotype_0001147 . obo:WBPhenotype_0001145 obo:IAO_0000115 "Polar body number is abnormal in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "polar body number abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001145" ; a owl:Class ; rdfs:label "polar body number defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001144 . obo:WBPhenotype_0001146 obo:IAO_0000115 "Polar body size is abnormal in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "polar body size abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001146" ; a owl:Class ; rdfs:label "polar body size defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001144 . obo:WBPhenotype_0001147 obo:IAO_0000115 "Polar bodies are abnormal in the inviable one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "polar body abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001147" ; a owl:Class ; rdfs:label "polar body defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100 . obo:WBPhenotype_0001148 obo:IAO_0000115 "Polar body is reabsorbed in the one- to four-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001148" ; a owl:Class ; rdfs:label "polar body reabsorbed early emb" ; rdfs:subClassOf obo:WBPhenotype_0000777 . obo:WBPhenotype_0001149 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0001148 ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001149" ; a owl:Class ; rdfs:label "obsolete polar body reabsorbed first early emb" ; owl:deprecated true . obo:WBPhenotype_0001150 obo:IAO_0000115 "A polar body is reabsorbed in either the one cell- or the two-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001150" ; a owl:Class ; rdfs:label "polar body reabsorbed one two early emb" ; rdfs:subClassOf obo:WBPhenotype_0001148 . obo:WBPhenotype_0001151 obo:IAO_0000115 "Pronucleus is abnormal in the inviable embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pronucleus centrosomes abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001151" ; a owl:Class ; rdfs:label "pronucleus centrosomes defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001034 . obo:WBPhenotype_0001152 obo:IAO_0000115 "Pronucleus migration is abnormal in the inviable embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pronuclear migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001152" ; a owl:Class ; rdfs:label "pronuclear migration defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001151 . obo:WBPhenotype_0001153 obo:IAO_0000115 "Neither of the pronuclei migrate and they never meet." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001153" ; a owl:Class ; rdfs:label "pronuclear migration failure early emb" ; rdfs:subClassOf obo:WBPhenotype_0001152 . obo:WBPhenotype_0001154 obo:IAO_0000115 "Instead of the maternal pronucleus migrating to the posterior end of the one-cell embryo, the paternal pronucleus migrates to meet the maternal pronucleus in the anterior end." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001154" ; a owl:Class ; rdfs:label "paternal pronucleus migrates early emb" ; rdfs:subClassOf obo:WBPhenotype_0001152 . obo:WBPhenotype_0001155 obo:IAO_0000115 "The maternal and paternal pronuclei meet more centrally instead of meeting in the posterior end of the embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001155" ; a owl:Class ; rdfs:label "pronuclei meet centrally early emb" ; rdfs:subClassOf obo:WBPhenotype_0001152 . obo:WBPhenotype_0001156 obo:IAO_0000115 "Maternal or paternal pronucleus is either too small or too large." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pronuclear size abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001156" ; a owl:Class ; rdfs:label "pronuclear size defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001026, obo:WBPhenotype_0001159, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000117 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045120 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000117 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045120 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001157 obo:IAO_0000115 "Pronuclear breakdown is atypical in the inviable embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pronuclear breakdown abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001157" ; a owl:Class ; rdfs:label "pronuclear breakdown defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001151 . obo:WBPhenotype_0001158 obo:IAO_0000115 "Instead of breaking down synchronously, the two pronuclei break down asynchronously in the inviable one-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001158" ; a owl:Class ; rdfs:label "pronuclear breakdown asynchronous early emb" ; rdfs:subClassOf obo:WBPhenotype_0001157 . obo:WBPhenotype_0001159 obo:IAO_0000115 "Pronucleus morphology is atypical in the inviable embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pronuclear morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001159" ; a owl:Class ; rdfs:label "pronuclear morphology defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001151 . obo:WBPhenotype_0001160 obo:IAO_0000115 "Morphology of the pronuclear envelope is atypical in the inviable embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pronuclear envelope morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001160" ; a owl:Class ; rdfs:label "pronuclear envelope morphology defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001159 . obo:WBPhenotype_0001161 obo:IAO_0000115 "Maternal pronucleus has a blurry appearance. The nuclear envelope does not have a crisp circular shape." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001161" ; a owl:Class ; rdfs:label "maternal pronucleus indistinct early emb" ; rdfs:subClassOf obo:WBPhenotype_0001160 . obo:WBPhenotype_0001162 obo:IAO_0000115 "There are more than two pronuclei in the inviable embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pronuclear number abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001162" ; a owl:Class ; rdfs:label "pronuclear number defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001142, obo:WBPhenotype_0001151, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045120 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045120 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001163 obo:IAO_0000115 "Either the maternal or paternal pronucleus is absent." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001163" ; a owl:Class ; rdfs:label "pronucleus formation failure early emb" ; rdfs:subClassOf obo:WBPhenotype_0001162 . obo:WBPhenotype_0001164 obo:IAO_0000115 "There is either more than one maternal or paternal pronucleus in the inviable embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001164" ; a owl:Class ; rdfs:label "excess pronucleus early emb" ; rdfs:subClassOf obo:WBPhenotype_0001162, obo:WBPhenotype_0002175 . obo:WBPhenotype_0001165 obo:IAO_0000115 "One-cell embryos have two or more maternal pronuclei." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001165" ; a owl:Class ; rdfs:label "excess maternal pronucleus early emb" ; rdfs:subClassOf obo:WBPhenotype_0001164, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0001939 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0001939 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000004 ] ) ] ] . obo:WBPhenotype_0001166 obo:IAO_0000115 "More than one paternal pronucleus is present in the inviable one-cell embryo or there is a defect in centrosome structure." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "excess paternal pronucleus abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001166" ; a owl:Class ; rdfs:label "excess paternal pronucleus variant centrosome early emb" ; rdfs:subClassOf obo:WBPhenotype_0001164 . obo:WBPhenotype_0001167 obo:IAO_0000115 "Pseudocleavage is atypical in the inviable one-cell embryo." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "pseudocleavage abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001167" ; a owl:Class ; rdfs:label "pseudocleavage defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100 . obo:WBPhenotype_0001168 obo:IAO_0000115 "No pseudocleavage is observed before or during pronuclear migration." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "no pseudocleavage" ; oboInOwl:id "WBPhenotype:0001168" ; a owl:Class ; rdfs:label "pseudocleavage absent early emb" ; rdfs:subClassOf obo:WBPhenotype_0001167, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030590 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030590 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001169 obo:IAO_0000115 "Embryos have more pronounced pseudocleavage than normal." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001169" ; a owl:Class ; rdfs:label "pseudocleavage exaggerated early emb" ; rdfs:subClassOf obo:WBPhenotype_0001167, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030588 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030588 ] ) ] ] . obo:WBPhenotype_0001170 obo:IAO_0000115 "Injected worm stops producing embryos 48 hours after RNAi injection and contains no live/developing embryos at this time." ; oboInOwl:hasBroadSynonym "Ste" ; oboInOwl:hasNarrowSynonym "P0 sterile" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001170" ; a owl:Class ; rdfs:label "sterile F0 48 hours post injection" ; rdfs:subClassOf obo:WBPhenotype_0000689 . obo:WBPhenotype_0001171 obo:IAO_0000115 "The duration of viability in the adult phase of the life-cycle is less than that of control animals." ; oboInOwl:hasBroadSynonym "Age" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "life span reduced", "longevity decreased" ; oboInOwl:id "WBPhenotype:0001171" ; a owl:Class ; rdfs:label "shortened life span" ; rdfs:subClassOf obo:WBPhenotype_0000039, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001604 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001604 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] . obo:WBPhenotype_0001172 obo:IAO_0000115 "Developmentally regulated termination of a cell or cell group does not occur as in control animals." ; oboInOwl:hasNarrowSynonym "programmed cell death abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001172" ; a owl:Class ; rdfs:label "programmed cell death variant" ; rdfs:subClassOf obo:WBPhenotype_0000729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0012501 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0012501 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001173 obo:IAO_0000115 "Animals exhibit variations in the specific activation or halting of processes within a cell that occur through necrosis or programmed cell death pathways different from apoptosis, so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death, compared to control." ; oboInOwl:hasNarrowSynonym "non apoptotic cell death abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001173" ; a owl:Class ; rdfs:label "non apoptotic cell death variant" ; rdfs:subClassOf obo:WBPhenotype_0001172 . obo:WBPhenotype_0001174 obo:IAO_0000115 "Chromosomes fail to segregate away from their homolog, resulting in gametes with no or extra copies of the chromosome." ; oboInOwl:hasNarrowSynonym "chromosome disjunction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001174" ; a owl:Class ; rdfs:label "chromosome disjunction defective" ; rdfs:subClassOf obo:WBPhenotype_0001499, obo:WBPhenotype_0001882, obo:WBPhenotype_0002012 . obo:WBPhenotype_0001175 obo:IAO_0000115 "Higher numbers of male progeny occur in the population compared to control populations. In C. elegans, the high incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an increase in X chromosome nondisjunction." ; oboInOwl:hasBroadSynonym "Him" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "high frequency X chromosome nondisjunction" ; oboInOwl:id "WBPhenotype:0001175" ; a owl:Class ; rdfs:label "high incidence male progeny" ; rdfs:subClassOf obo:WBPhenotype_0001664 . obo:WBPhenotype_0001176 obo:IAO_0000115 "One-cell embryos have an altered shape." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasNarrowSynonym "one cell shape abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001176" ; a owl:Class ; rdfs:label "one cell shape defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001135, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000052 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000006 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000052 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000006 ] ) ] ] . obo:WBPhenotype_0001177 obo:IAO_0000115 "Embryos rupture when placed on a 2% agar pad and covered with a coverslip." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001177" ; a owl:Class ; rdfs:label "embryo osmotic pressure sensitive early emb" ; rdfs:subClassOf obo:WBPhenotype_0001178 . obo:WBPhenotype_0001178 obo:IAO_0000115 "The structure of the egg is impaired, flawed or no longer intact." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001178" ; a owl:Class ; rdfs:label "egg integrity defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001100, obo:WBPhenotype_0002075 . obo:WBPhenotype_0001179 obo:IAO_0000115 "OBSOLETE. Phenotypic examination of worms did not reveal an obvious abnormality compared with control animals." ; oboInOwl:hasNarrowSynonym "No abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "WT" ; oboInOwl:id "WBPhenotype:0001179" ; a owl:Class ; rdfs:comment "The phenotype ontology was restructured such that \"Abnormal\" is now the root term. The term \"Abnormal\" with a \"Not\" qualifier is a suggested replacement for this term.", "This phenotype was intended to reflect a lack of any phenotypic abnormality in the individuals in question. The C. elegans phenotype ontology no longer has terms specifically used to assert negation of a phenotype." ; rdfs:label "obsolete No variantity scored" ; owl:deprecated true . obo:WBPhenotype_0001180 obo:IAO_0000115 "Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001180" ; a owl:Class ; rdfs:label "accumulated germline cell corpses" ; rdfs:subClassOf obo:WBPhenotype_0000241 . obo:WBPhenotype_0001181 obo:IAO_0000115 "Animals exhibit an increase in the quantity of non-germ line cells that have undergone programmed cell death but have not been engulfed." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001181" ; a owl:Class ; rdfs:label "accumulated somatic cell corpses" ; rdfs:subClassOf obo:WBPhenotype_0000241 . obo:WBPhenotype_0001182 obo:IAO_0000115 "Animals exhibit variations in the amount of fat or lipids present in the organism compared to control animals." ; oboInOwl:hasNarrowSynonym "fat content abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lipid content abnormal", "lipid content variant" ; oboInOwl:id "WBPhenotype:0001182" ; a owl:Class ; rdfs:label "fat content variant" ; rdfs:subClassOf obo:WBPhenotype_0000725, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_18059 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_18059 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001183 obo:IAO_0000115 "Animals exhibit less fat or lipid than observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lipid content reduced" ; oboInOwl:id "WBPhenotype:0001183" ; a owl:Class ; rdfs:label "fat content reduced" ; rdfs:subClassOf obo:WBPhenotype_0001182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_18059 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_18059 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001184 obo:IAO_0000115 "Animals exhibit a greater amount of fat or lipids than observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lipid content increased" ; oboInOwl:id "WBPhenotype:0001184" ; a owl:Class ; rdfs:label "fat content increased" ; rdfs:subClassOf obo:WBPhenotype_0001182, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_18059 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_18059 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001185 obo:IAO_0000115 "The developmental progression of an early embryo over time, from its formation to its mature structure is delayed compared to control." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001185" ; a owl:Class ; rdfs:label "embryonic developmental delay early emb" ; rdfs:subClassOf obo:WBPhenotype_0000848, obo:WBPhenotype_0001100 . obo:WBPhenotype_0001186 obo:IAO_0000115 "Embryos are either delayed or arrested at pronuclear contact." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001186" ; a owl:Class ; rdfs:label "embryo delayed at pronuclear contact early emb" ; rdfs:subClassOf obo:WBPhenotype_0001185 . obo:WBPhenotype_0001187 obo:IAO_0000115 "EMS divides before P2." ; oboInOwl:hasBroadSynonym "Emb" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001187" ; a owl:Class ; rdfs:label "division EMS before P2 early emb" ; rdfs:subClassOf obo:WBPhenotype_0001120 . obo:WBPhenotype_0001188 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of radial arrangement of actin within the pharyngeal muscle compared to control animals." ; oboInOwl:hasNarrowSynonym "radial filament structure abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001188" ; a owl:Class ; rdfs:label "radial filament structure variant pharynx" ; rdfs:subClassOf obo:WBPhenotype_0001046 . obo:WBPhenotype_0001189 obo:IAO_0000115 "Any variation in the cell junctions of the pharyngeal muscle at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control." ; oboInOwl:hasNarrowSynonym "adherens junctions abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001189" ; a owl:Class ; rdfs:label "adherens junctions variant pharyngeal muscle" ; rdfs:subClassOf obo:WBPhenotype_0001046, obo:WBPhenotype_0001745 . obo:WBPhenotype_0001190 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the pharynx to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "pharyngeal physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001190" ; a owl:Class ; rdfs:label "pharyngeal physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000606, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001191 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for muscles in the pharynx to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "pharyngeal muscle physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001191" ; a owl:Class ; rdfs:label "pharyngeal muscle physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000990, obo:WBPhenotype_0001190, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005451 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005451 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001192 obo:IAO_0000115 "Any variation in the series of molecular signals in which a pharyngeal cell uses calcium ions to convert an extracellular signal into a response, compared to control." ; oboInOwl:hasNarrowSynonym "calcium signaling pharynx abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001192" ; a owl:Class ; rdfs:label "calcium signaling in pharynx variant" ; rdfs:subClassOf obo:WBPhenotype_0001191, obo:WBPhenotype_0002170, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0019722 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0019722 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001193 obo:IAO_0000115 "Electropharyngeograms do not show a similar pattern as control animals. C. elegans animals show a repeating regular pattern in which each pump is associated with an excitatory depolarizing wave, often punctuated by brief negative spikes, followed by a plateau phase, and ending with an inhibitory hyperpolarizing wave." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001193" ; a owl:Class ; rdfs:label "disorganized pharyngeal EPG" ; rdfs:subClassOf obo:WBPhenotype_0000980 . obo:WBPhenotype_0001194 obo:IAO_0000115 "Animals have one or more extra neurons, which are present in places they are normally not found, when compared to the number and location of these neurons in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001194" ; a owl:Class ; rdfs:label "extra and ectopic neuron" ; rdfs:subClassOf obo:WBPhenotype_0001303 . obo:WBPhenotype_0001195 obo:IAO_0000115 "Rhythmic calcium increases in the pharynx are observed less often than in control animals. In C. elegans, rhythmic increases in intracellular calcium are often observed using a transgenically expressed cameleon, a ratiometric calcium indicator." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001195" ; a owl:Class ; rdfs:label "generation calcium signal defective pharynx" ; rdfs:subClassOf obo:WBPhenotype_0001192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050848 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050848 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] . obo:WBPhenotype_0001196 obo:IAO_0000115 "Calcium spikes lack synchrony in the musculature of the corpus and the terminal bulb as seen in control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001196" ; a owl:Class ; rdfs:label "synchronization calcium signal defective pharynx" ; rdfs:subClassOf obo:WBPhenotype_0001192, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000688 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0019722 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000688 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0019722 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] . obo:WBPhenotype_0001197 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic gonad to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "somatic gonad physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001197" ; a owl:Class ; rdfs:label "somatic gonad physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000613, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005785 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005785 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001198 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the somatic sheath system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "somatic sheath physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001198" ; a owl:Class ; rdfs:label "somatic sheath physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000929, obo:WBPhenotype_0000990, obo:WBPhenotype_0001197, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005828 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005828 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001199 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the contraction of a thin continuous tube surrounding the proximal portions of the ovary and covering the maturing oocytes to the near portion of the distal gonad arm, compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "gonad sheath contractions abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001199" ; a owl:Class ; rdfs:label "gonad sheath contractions variant" ; rdfs:subClassOf obo:WBPhenotype_0001198 . obo:WBPhenotype_0001200 obo:IAO_0000115 "Basal contraction rate and or peak contraction rate of the gonadal sheath is reduced relative to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001200" ; a owl:Class ; rdfs:label "gonad sheath contraction rate reduced" ; rdfs:subClassOf obo:WBPhenotype_0001199 . obo:WBPhenotype_0001201 obo:IAO_0000115 "Animals lack the stereotyped muscle contractions that result in the opening of anus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001201" ; a owl:Class ; rdfs:label "no expulsion defecation" ; rdfs:subClassOf obo:WBPhenotype_0000391 . obo:WBPhenotype_0001202 obo:IAO_0000115 "Animals respond to nicotine at lower concentrations or shorter exposure compared to control. Nicotine is a cholinergic agonist." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001202" ; a owl:Class ; rdfs:label "nicotine hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001573, obo:WBPhenotype_0001579, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18723 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18723 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001203 obo:IAO_0000115 "Animals fail to respond to the concentration of nicotine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001203" ; a owl:Class ; rdfs:label "nicotine resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001573, obo:WBPhenotype_0001578, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18723 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18723 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001204 obo:IAO_0000115 "Animals fail to respond to the concentration of muscimol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001204" ; a owl:Class ; rdfs:label "muscimol resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, obo:WBPhenotype_0002047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_7035 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_7035 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001205 obo:IAO_0000115 "Animals respond to muscimol at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001205" ; a owl:Class ; rdfs:label "muscimol hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001918, obo:WBPhenotype_0002047, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_7035 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_7035 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001206 obo:IAO_0000115 "Variations in the process by which an organism travels from one location to another compared to control." ; oboInOwl:hasNarrowSynonym "movement abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001206" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "movement variant" ; rdfs:subClassOf obo:WBPhenotype_0000525 . obo:WBPhenotype_0001207 obo:IAO_0000115 "Any variation in a series of protein mediated signals that help relay information within the cell, and thereby affecting changes in the functioning of the cell, compared to control." ; oboInOwl:hasNarrowSynonym "protein signaling abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001207" ; a owl:Class ; rdfs:label "protein signaling variant" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0001208 obo:IAO_0000115 "Animals show reduced susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control." ; oboInOwl:hasBroadSynonym "Rde" ; oboInOwl:hasExactSynonym "RNAi deficient" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001208" ; a owl:Class ; rdfs:label "RNAi resistant" ; rdfs:subClassOf obo:WBPhenotype_0000743, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000513 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016246 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000513 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016246 ] ) ] ] . obo:WBPhenotype_0001209 obo:IAO_0000115 "Apparently normal sinusoidal movement, but appear to have poor traction on the agar surface of a culture plate." ; oboInOwl:hasBroadSynonym "Skd" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001209" ; a owl:Class ; rdfs:label "skiddy" ; rdfs:subClassOf obo:WBPhenotype_0001701 . obo:WBPhenotype_0001210 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process taking place in extracellular spaces within or associated with the organism, from that observed for control animals." ; oboInOwl:hasExactSynonym "pericellular component physiology abnormal", "pericellular component physiology variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001210" ; oboInOwl:inSubset wbphenotype:phenotype_slim_wb ; a owl:Class ; rdfs:label "pericellular component physiology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000519, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005732 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005732 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001211 obo:IAO_0000115 "The physical strength or function of the cuticle varies from that observed for control animals." ; oboInOwl:hasNarrowSynonym "cuticle integrity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001211" ; a owl:Class ; rdfs:label "cuticle integrity variant" ; rdfs:subClassOf obo:WBPhenotype_0001678 . obo:WBPhenotype_0001212 obo:IAO_0000115 "The strength of the cuticle is less robust than that observed for control animals. In C. elegans the strength of the cuticle is often assayed by it's ability to protect the animal from exposure to bleach or other compounds." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001212" ; a owl:Class ; rdfs:label "cuticle fragile" ; rdfs:subClassOf obo:WBPhenotype_0002640, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001362 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001362 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] ) ] ] . obo:WBPhenotype_0001213 obo:IAO_0000115 "Animals exhibit a decrease in any parameter used to measure locomotion compared to control animals." ; oboInOwl:hasAlternativeId "WBPhenotype:0001288" ; oboInOwl:hasExactSynonym "movement reduced" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001213" ; a owl:Class ; rdfs:label "locomotion reduced" ; rdfs:subClassOf obo:WBPhenotype_0000641, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007626 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040011 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007626 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040011 ] ) ] ] . obo:WBPhenotype_0001214 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0001496 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001214" ; a owl:Class ; rdfs:label "obsolete metaphase to anaphase transition fails" ; owl:deprecated true . obo:WBPhenotype_0001215 obo:IAO_0000115 "Variations in the mitotic expansion of germ cell populations or in the appearance of nuclei during development in the premeiotic region of the germline compared to control." ; oboInOwl:hasNarrowSynonym "germ cell mitosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001215" ; a owl:Class ; rdfs:label "germ cell mitosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000823 . obo:WBPhenotype_0001216 obo:IAO_0000115 "Oocyte chromosomes arrest in metaphase of meiosis I without transitioning to anaphase or producing polar bodies." ; oboInOwl:hasBroadSynonym "Mat" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001216" ; a owl:Class ; rdfs:label "meiosis metaphase to anaphase transition block" ; rdfs:subClassOf obo:WBPhenotype_0000775, obo:WBPhenotype_0001496 . obo:WBPhenotype_0001217 obo:IAO_0000115 "Germ line cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001217" ; a owl:Class ; rdfs:label "germ cell mitosis metaphase to anaphase transition block" ; rdfs:subClassOf obo:WBPhenotype_0001215, obo:WBPhenotype_0001497 . obo:WBPhenotype_0001218 obo:IAO_0000115 "Animals exhibit variations in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations." ; oboInOwl:hasNarrowSynonym "cell death sexually dimorphic abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001218" ; a owl:Class ; rdfs:label "cell death sexually dimorphic variant" ; rdfs:subClassOf obo:WBPhenotype_0000730 . obo:WBPhenotype_0001219 obo:IAO_0000115 "Animals exhibit a decrease in the rate or extent of programmed cell death and thus an increase in cell survival, as it pertains to a sex-specific feature, compared to control populations." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001219" ; a owl:Class ; rdfs:label "cell survival sexually dimorphic increased" ; rdfs:subClassOf obo:WBPhenotype_0001218 . obo:WBPhenotype_0001220 obo:IAO_0000115 "Animals exhibit in increase in the rate or extent of programmed cell death as it pertains to a sex-specific feature, compared to control populations." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001220" ; a owl:Class ; rdfs:label "cell death sexually dimorphic increased" ; rdfs:subClassOf obo:WBPhenotype_0001218 . obo:WBPhenotype_0001221 obo:IAO_0000115 "Animal fails to exhibit characteristic response after a nose-on collision with an object compared to control. In C. elegans, this is usually assayed with a hair or similar fiber. The nose is the anterior most tip of the animal." ; oboInOwl:hasBroadSynonym "Not" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001221" ; a owl:Class ; rdfs:label "nose touch defective" ; rdfs:subClassOf obo:WBPhenotype_0000456, obo:WBPhenotype_0004026 . obo:WBPhenotype_0001222 obo:IAO_0000115 "Animals exhibit an increase in frequency of transposition events (DNA movement to different positions within the genome of a single cell) causing an accumulation of lesions within the genome, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Mut", "mutator" ; oboInOwl:id "WBPhenotype:0001222" ; a owl:Class ; rdfs:label "transposon mutator" ; rdfs:subClassOf obo:WBPhenotype_0000228 . obo:WBPhenotype_0001223 obo:IAO_0000115 "Animals show reduced susceptibility to gene silencing in the germline triggered by double stranded RNA (RNAi), compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001223" ; a owl:Class ; rdfs:label "germline RNAi resistant" ; rdfs:subClassOf obo:WBPhenotype_0001208 . obo:WBPhenotype_0001224 obo:IAO_0000115 "Any variation in the processes that govern the extension of axons compared to control." ; oboInOwl:hasNarrowSynonym "axon outgrowth abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "axon migration variant" ; oboInOwl:id "WBPhenotype:0001224" ; a owl:Class ; rdfs:label "axon outgrowth variant" ; rdfs:subClassOf obo:WBPhenotype_0000572 . obo:WBPhenotype_0001225 obo:IAO_0000115 "Animals are missing the interfacial hypodermal cell (socket cell) of the phasmid sensillum pore." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Psa" ; oboInOwl:id "WBPhenotype:0001225" ; a owl:Class ; rdfs:label "phasmid socket absent" ; rdfs:subClassOf obo:WBPhenotype_0001527, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008410 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008410 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001226 obo:IAO_0000115 "Animals display variations in the structure, organization or path of the part of the axon that forms a bridge between body regions, compared to that in control animals." ; oboInOwl:hasNarrowSynonym "commissure abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001226" ; a owl:Class ; rdfs:label "commissure variant" ; rdfs:subClassOf obo:WBPhenotype_0000181 . obo:WBPhenotype_0001227 obo:IAO_0000115 "Animals are missing any one of its commissures, an axon tract that connects one body part to another." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001227" ; a owl:Class ; rdfs:label "commissure absent" ; rdfs:subClassOf obo:WBPhenotype_0001226 . obo:WBPhenotype_0001228 obo:IAO_0000115 "Animals lack the small linear ridges running along the lateral lines of the cuticle, lengthwise along the body (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001228" ; a owl:Class ; rdfs:label "alae absent" ; rdfs:subClassOf obo:WBPhenotype_0000202, obo:WBPhenotype_0002558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007832 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007832 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001229 obo:IAO_0000115 "The orderly movement of neurons along the anterior axis of the animal is abolished, misdirected or incomplete compared to control." ; oboInOwl:hasNarrowSynonym "abnormal anterior neuron migration" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001229" ; a owl:Class ; rdfs:label "anterior neuron migration defective" ; rdfs:subClassOf obo:WBPhenotype_0001140, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001632 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0001764 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001632 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0001764 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001230 obo:IAO_0000115 "The orderly movement of cells along the anterior axis of the animal is abolished, misdirected or incomplete compared to control." ; oboInOwl:hasNarrowSynonym "abnormal anterior cell migration" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001230" ; a owl:Class ; rdfs:label "anterior cell migration defective" ; rdfs:subClassOf obo:WBPhenotype_0000594, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001632 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016477 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001632 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016477 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001231 obo:IAO_0000115 "The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is increased compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ift accelerated" ; oboInOwl:id "WBPhenotype:0001231" ; a owl:Class ; rdfs:label "intraflagellar transport accelerated" ; rdfs:subClassOf obo:WBPhenotype_0000853, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001232 obo:IAO_0000115 "Animals exhibit variations in the response to the addition of serotonin compared to that observed in control animals. Serotonin is a monoamine neurotransmitter." ; oboInOwl:hasNarrowSynonym "serotonin response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001232" ; a owl:Class ; rdfs:label "serotonin response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001233 obo:IAO_0000115 "Animals exhibit variations in the pattern of a chemical nuclear stain which is commonly used in fixed specimens and produces a bright blue label, compared to control. DAPI (4'-6-Diamidino-2-phenylindole) forms fluorescent complexes with natural double-stranded DNA (Wormatlas)." ; oboInOwl:hasNarrowSynonym "DAPI staining abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001233" ; a owl:Class ; rdfs:label "DAPI staining variant" ; rdfs:subClassOf obo:WBPhenotype_0010002 . obo:WBPhenotype_0001234 obo:IAO_0000115 "Failure to execute the characteristic response to nonanone compared to control. In C. elegans, nonanone is a repellant." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001234" ; a owl:Class ; rdfs:label "nonanone chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001448, obo:WBPhenotype_0001456, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050919 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_25579 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050919 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_25579 ] ) ] ] . obo:WBPhenotype_0001235 obo:IAO_0000115 "Any variation in the orientation of the physical partitioning and separation of a cell into daughter cells compared to control." ; oboInOwl:hasNarrowSynonym "cell division polarity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001235" ; a owl:Class ; rdfs:label "cell division polarity variant" ; rdfs:subClassOf obo:WBPhenotype_0000746, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001769 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001769 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001236 obo:IAO_0000115 "Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001236" ; a owl:Class ; rdfs:label "transgene expression increased" ; rdfs:subClassOf obo:WBPhenotype_0000962 . obo:WBPhenotype_0001237 obo:IAO_0000115 "Any perturbation that causes an increase in the frequency of axon outgrowth compared to control. As a result, an excess number of axonal projections are generated." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001237" ; a owl:Class ; rdfs:label "excess axon outgrowth" ; rdfs:subClassOf obo:WBPhenotype_0000629, obo:WBPhenotype_0001224 . obo:WBPhenotype_0001238 obo:IAO_0000115 "Any variation in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva." ; oboInOwl:hasNarrowSynonym "male mating latency abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001238" ; a owl:Class ; rdfs:label "male mating latency variant" ; rdfs:subClassOf obo:WBPhenotype_0000648, obo:WBPhenotype_0002551, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001005 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007618 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001005 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007618 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001239 obo:IAO_0000115 "Any increase in the length of time required for a male to find a mate and initiate the search for the vulva. In C. elegans, the latency period includes the time males spend to find a hermaphrodite and pause to press its ventral side against the surface of the hermaphrodite and initiate a backing up search for the vulva." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001239" ; a owl:Class ; rdfs:label "mating latency increased" ; rdfs:subClassOf obo:WBPhenotype_0001238, obo:WBPhenotype_0001414 . obo:WBPhenotype_0001240 obo:IAO_0000115 "Variations in the processes leading to the specialization of the finger-like sensory sensilla that project from the tail and embed in the male fan compared to control." ; oboInOwl:hasNarrowSynonym "male tail sensory ray differentiation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001240" ; a owl:Class ; rdfs:label "male tail sensory ray differentiation variant" ; rdfs:subClassOf obo:WBPhenotype_0000199 . obo:WBPhenotype_0001241 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000297 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001241" ; a owl:Class ; rdfs:label "obsolete ray fusion" ; owl:deprecated true . obo:WBPhenotype_0001242 obo:IAO_0000115 "The rate, frequency or extent of bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is lower compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001242" ; a owl:Class ; rdfs:label "intraflagellar transport slow" ; rdfs:subClassOf obo:WBPhenotype_0000854, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001243 obo:IAO_0000115 "The bidirectional transport of molecules (cargo) along axonemal microtubules is reduced compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001243" ; a owl:Class ; rdfs:label "intraflagellar transport distance short" ; rdfs:subClassOf obo:WBPhenotype_0001247, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000375 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000375 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] ) ] ] . obo:WBPhenotype_0001244 obo:IAO_0000115 "Bidirectional movement of large protein complexes (mediated by motor proteins) along microtubules within a cilium or flagellum is completely abolished." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001244" ; a owl:Class ; rdfs:label "intraflagellar transport absent" ; rdfs:subClassOf obo:WBPhenotype_0000854, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042073 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001245 obo:IAO_0000115 "The bidirectional transport of molecules along the middle segment of axonemal microtubules of the cilia is absent." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001245" ; a owl:Class ; rdfs:label "no transport middle segment cilia" ; rdfs:subClassOf obo:WBPhenotype_0001243 . obo:WBPhenotype_0001246 obo:IAO_0000115 "The bidirectional transport of molecules along the distal segment of axonemal microtubules of the cilia is absent." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001246" ; a owl:Class ; rdfs:label "no transport distal segment cilia" ; rdfs:subClassOf obo:WBPhenotype_0001243 . obo:WBPhenotype_0001247 obo:IAO_0000115 "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons is disrupted." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001247" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "anterograde transport defective" ; rdfs:subClassOf obo:WBPhenotype_0000854, obo:WBPhenotype_0001477, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048490 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048490 ] ) ] ] . obo:WBPhenotype_0001248 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the microtuble-based projections that in control animals invaginate individually into the sheath cell of the neuronal sensillum rather than projecting through the socket cell to the outside. In C. elegans, the cilia of each wing cell has its own unique shape and as they are not exposed to the outside, they do not typically take up dyes." ; oboInOwl:hasNarrowSynonym "wing cilia morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "AWC cilia morphology abnormal" ; oboInOwl:id "WBPhenotype:0001248" ; a owl:Class ; rdfs:label "wing cilia morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000615 . obo:WBPhenotype_0001249 obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the dendritic projections of the amphid sensory neurons that traverse the sensillum pore to connect with the outside of the animal, compared to that observed in control animals. In C. elegans, amphid channel cilia morphology is frequently assayed by dye-filling experiments using FITC, DiI or DiO." ; oboInOwl:hasNarrowSynonym "amphid channel cilia morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001249" ; a owl:Class ; rdfs:label "amphid channel cilia morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000615 . obo:WBPhenotype_0001250 obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the microtuble-based fibrillar core, axoneme, of the cilia of the neurons that project through the sensillum pore to the outside of the animal, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "amphid channel axoneme morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001250" ; a owl:Class ; rdfs:label "amphid channel axoneme morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000262, obo:WBPhenotype_0001249 . obo:WBPhenotype_0001251 obo:IAO_0000115 "The microtuble-based fibrillar-bundles of the amphid sensory cilia are reduced in length compared to those in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001251" ; a owl:Class ; rdfs:label "amphid channel axoneme short" ; rdfs:subClassOf obo:WBPhenotype_0001250 . obo:WBPhenotype_0001252 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the microtubule-based fibrillar section, axoneme, of the cilia of the flat sheet-like cells associated with sensory function, from that observed in control animals." ; oboInOwl:hasNarrowSynonym "wing cilia axoneme morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001252" ; a owl:Class ; rdfs:label "wing cilia axoneme morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001248 . obo:WBPhenotype_0001253 obo:IAO_0000115 "The microtuble-based fibrillar-bundle, axoneme, of the wing cell cilia are reduced in length and do not extend into the sheath cell as far as they do in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001253" ; a owl:Class ; rdfs:label "wing cilia axoneme short" ; rdfs:subClassOf obo:WBPhenotype_0001252 . obo:WBPhenotype_0001254 obo:IAO_0000115 "The dendritic processes that normally extend through the amphid sensillum pore to the outside are truncated and have swollen ends as opposed to the extended and finger-like tips of channel cilia in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001254" ; a owl:Class ; rdfs:label "amphid channel cilia bulbous" ; rdfs:subClassOf obo:WBPhenotype_0001249 . obo:WBPhenotype_0001255 obo:IAO_0000115 "Animals exhibit wing cell sensory cilia that are truncated and swollen unlike that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001255" ; a owl:Class ; rdfs:label "wing cilia bulbous" ; rdfs:subClassOf obo:WBPhenotype_0001248 . obo:WBPhenotype_0001256 obo:IAO_0000115 "Variations in the aggregation of molecules at the site of DNA strand breakage or damage compared to control." ; oboInOwl:hasNarrowSynonym "DNA damage induced focus formation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "DNA repair induced focus formation" ; oboInOwl:id "WBPhenotype:0001256" ; a owl:Class ; rdfs:label "DNA damage induced focus formation variant" ; rdfs:subClassOf obo:WBPhenotype_0000739 . obo:WBPhenotype_0001257 obo:IAO_0000115 "Variations in the generation of foci that mark sites of aberrant bonding of molecules to the DNA strand, compared to control." ; oboInOwl:hasNarrowSynonym "cross link induced focus formation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001257" ; a owl:Class ; rdfs:label "cross link induced focus formation variant" ; rdfs:subClassOf obo:WBPhenotype_0001256 . obo:WBPhenotype_0001258 obo:IAO_0000115 "Animals show increased susceptibility to gene silencing triggered by double stranded RNA (RNAi), compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Eri" ; oboInOwl:id "WBPhenotype:0001258" ; a owl:Class ; rdfs:label "RNAi enhanced" ; rdfs:subClassOf obo:WBPhenotype_0000743, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002017 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016246 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002017 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016246 ] ) ] ] . obo:WBPhenotype_0001259 obo:IAO_0000115 "Hermaphrodites exhibit a reduction in the production of new individuals owing to defects in gamete competence and/or function compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001259" ; a owl:Class ; rdfs:label "hermaphrodite fertility reduced" ; rdfs:subClassOf obo:WBPhenotype_0000806 . obo:WBPhenotype_0001260 obo:IAO_0000115 "Haploid female germ cells (oocytes) exhibit variations in their overall structure, appearance or contents compared to control." ; oboInOwl:hasNarrowSynonym "oocyte morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001260" ; a owl:Class ; rdfs:label "oocyte morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000900, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006797 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006797 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001261 obo:IAO_0000115 "Animals show deficiencies in chroma resulting in increased translucency." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001261" ; a owl:Class ; rdfs:label "pale" ; rdfs:subClassOf obo:WBPhenotype_0000527 . obo:WBPhenotype_0001262 obo:IAO_0000115 "The developmental progression of the egg-laying organ of female and hermaphrodite nematodes is halted prior to the formation of the mature structure." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001262" ; a owl:Class ; rdfs:label "vulval development incomplete" ; rdfs:subClassOf obo:WBPhenotype_0000699, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040025 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0040025 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001263 obo:IAO_0000115 "The morphological appearance of peroxisomes is variant compared to control animals." ; oboInOwl:hasNarrowSynonym "peroxisome morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001263" ; a owl:Class ; rdfs:label "peroxisome morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005777 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005777 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001264 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the peroxisome to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "peroxisome physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001264" ; a owl:Class ; rdfs:label "peroxisome physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005777 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005777 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001265 obo:IAO_0000115 "The anterior portion of the animal exhibits variations in its movement compared to control." ; oboInOwl:hasNarrowSynonym "Erratic head vibration", "head movement abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001265" ; a owl:Class ; rdfs:label "head movement variant" ; rdfs:subClassOf obo:WBPhenotype_0001699 . obo:WBPhenotype_0001266 obo:IAO_0000115 "Any variation in triggering of the set of interactions occurring between a group of genes who depend on each other's individual functions in order to make the aggregate function of the network available to the cell, compared to control." ; oboInOwl:hasNarrowSynonym "genetic pathway activation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001266" ; a owl:Class ; rdfs:label "genetic pathway activation variant" ; rdfs:subClassOf obo:WBPhenotype_0000074 . obo:WBPhenotype_0001267 obo:IAO_0000115 "Any variation in the frequency of gonad sheath contractions triggered by internal or external stimuli compared to control." ; oboInOwl:hasNarrowSynonym "induced contraction rate abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001267" ; a owl:Class ; rdfs:label "induced contraction rate variant" ; rdfs:subClassOf obo:WBPhenotype_0001199 . obo:WBPhenotype_0001268 obo:IAO_0000115 "Animals exhibit variations in the extent of activation of programmed cell death, compared to control." ; oboInOwl:hasNarrowSynonym "induced cell death abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001268" ; a owl:Class ; rdfs:label "induced cell death variant" ; rdfs:subClassOf obo:WBPhenotype_0000729, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043068 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043068 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001269 obo:IAO_0000115 "Animals exhibit variations in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." ; oboInOwl:hasNarrowSynonym "pathogen induced cell death abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001269" ; a owl:Class ; rdfs:label "pathogen induced cell death variant" ; rdfs:subClassOf obo:WBPhenotype_0001268 . obo:WBPhenotype_0001270 obo:IAO_0000115 "Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to a pathogen or pathogenic cue, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001270" ; a owl:Class ; rdfs:label "pathogen induced cell death reduced" ; rdfs:subClassOf obo:WBPhenotype_0001269 . obo:WBPhenotype_0001271 obo:IAO_0000115 "Animals are more prone to lethality as a result of infection compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001271" ; a owl:Class ; rdfs:label "pathogen induced death increased" ; rdfs:subClassOf obo:WBPhenotype_0001013 . obo:WBPhenotype_0001272 obo:IAO_0000115 "Vulval precursor cells inappropriately adopt fates that are normally restricted to other vulval precursor cells compared to control." ; oboInOwl:hasExactSynonym "vulval precursor cell induction abnormal" ; oboInOwl:hasNarrowSynonym "vulval cell induction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001272" ; a owl:Class ; rdfs:label "vulval cell induction variant" ; rdfs:subClassOf obo:WBPhenotype_0000220 . obo:WBPhenotype_0001273 obo:IAO_0000115 "Any variation in the state or activity of an organism (in terms of movement, gene expression, etc.) in response to heat (high temperatures above the optimal temperature for that organism), compared to control." ; oboInOwl:hasNarrowSynonym "organism heat response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001273" ; a owl:Class ; rdfs:label "organism heat response variant" ; rdfs:subClassOf obo:WBPhenotype_0000146, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009408 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009408 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001274 obo:IAO_0000115 "Animals respond to heat at a lower temperature or a shorter exposure time compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001274" ; a owl:Class ; rdfs:label "organism heat hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001273 . obo:WBPhenotype_0001275 obo:IAO_0000115 "Any variation that increases the magnitude of a signal generated by a set of gene interactions in a given pathway, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001275" ; a owl:Class ; rdfs:label "increased genetic pathway signal" ; rdfs:subClassOf obo:WBPhenotype_0000074 . obo:WBPhenotype_0001276 obo:IAO_0000115 "Any variation in the cellular expression of a gene product produced by exogenous DNA that has been introduced into the organism such that it now expresses in cells/tissues not seen when compared to the expression of that gene product in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001276" ; a owl:Class ; rdfs:label "ectopic expression transgene" ; rdfs:subClassOf obo:WBPhenotype_0000961 . obo:WBPhenotype_0001277 obo:IAO_0000115 "XX animals are transformed into males or pseudomales ." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Tra" ; oboInOwl:id "WBPhenotype:0001277" ; a owl:Class ; rdfs:label "transformer" ; rdfs:subClassOf obo:WBPhenotype_0001572 . obo:WBPhenotype_0001278 obo:IAO_0000115 "Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001278" ; a owl:Class ; rdfs:label "transgene expression reduced" ; rdfs:subClassOf obo:WBPhenotype_0000962 . obo:WBPhenotype_0001279 obo:IAO_0000115 "Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the male, that has been introduced into the organism compared to its expression in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001279" ; a owl:Class ; rdfs:label "transgene expression reduced male" ; rdfs:subClassOf obo:WBPhenotype_0001278 . obo:WBPhenotype_0001280 obo:IAO_0000115 "Any decrease in the intensity of expression of a gene product produced by exogenous DNA, exclusively in the hermaphrodite, that has been introduced into the organism compared to its expression in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001280" ; a owl:Class ; rdfs:label "transgene expression reduced hermaphrodite" ; rdfs:subClassOf obo:WBPhenotype_0001278 . obo:WBPhenotype_0001281 obo:IAO_0000115 "Pharynx becomes clogged with food. In C. elegans, this is often a result of pharyngeal pumping defects." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001281" ; a owl:Class ; rdfs:label "stuffed pharynx" ; rdfs:subClassOf obo:WBPhenotype_0000634, obo:WBPhenotype_0000778, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001836 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001836 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] ) ] ] . obo:WBPhenotype_0001282 obo:IAO_0000115 "Variations in the chemical reactions and pathways of the mitochondria compared to control." ; oboInOwl:hasNarrowSynonym "mitochondrial metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001282" ; a owl:Class ; rdfs:label "mitochondrial metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0001283 . obo:WBPhenotype_0001283 obo:IAO_0000115 "Variations in the chemical reactions and pathways of an organelle compared to control." ; oboInOwl:hasNarrowSynonym "organelle metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001283" ; a owl:Class ; rdfs:label "organelle metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000585, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043226 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0043226 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001284 obo:IAO_0000115 "Animals contain a lower level of coenzyme Q, an oil-soluble vitamin-like substance present in most eukaryotic cells, primarily in the mitochondria, compared to control. It is a component of the electron transport chain and participates in aerobic cellular respiration." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001284" ; a owl:Class ; rdfs:label "coenzyme Q depleted" ; rdfs:subClassOf obo:WBPhenotype_0000026, obo:WBPhenotype_0001282 . obo:WBPhenotype_0001285 obo:IAO_0000115 "Pharyngeal pumping is not influenced by treatment with specific compounds (eg: serotonin) in the same manner as control animals." ; oboInOwl:hasNarrowSynonym "induced pharyngeal pumping abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001285" ; a owl:Class ; rdfs:label "induced pharyngeal pumping variant" ; rdfs:subClassOf obo:WBPhenotype_0001006 . obo:WBPhenotype_0001286 obo:IAO_0000115 "Exposure to food does not reduce pharyngeal pumping to the same extent as observed in control animals." ; oboInOwl:hasNarrowSynonym "food suppressed pumping abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001286" ; a owl:Class ; rdfs:label "food suppressed pumping variant" ; rdfs:subClassOf obo:WBPhenotype_0001072, obo:WBPhenotype_0001287 . obo:WBPhenotype_0001287 obo:IAO_0000115 "Animals do not exhibit a decrease in pumping rate when treated with specific compounds (such as pheromones) as is observed for control animals." ; oboInOwl:hasNarrowSynonym "suppressed pharyngeal pumping abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001287" ; a owl:Class ; rdfs:label "suppressed pharyngeal pumping defective" ; rdfs:subClassOf obo:WBPhenotype_0001006 . obo:WBPhenotype_0001288 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0001213 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001288" ; a owl:Class ; rdfs:comment "is alternative id for \"locomotion reduced\" (WBPhenotype:0001213); may have originally had term name \"movement reduced\"" ; owl:deprecated true . obo:WBPhenotype_0001289 obo:IAO_0000115 "Animals fail to respond to the concentration of acetylcholinesterase inhibitor that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001289" ; a owl:Class ; rdfs:label "acetylcholinesterase inhibitor resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001290, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38462 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38462 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001290 obo:IAO_0000115 "Animals exhibit variations in their response to a specific acetylcholinesterase inhibitor compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "acetylcholinesterase inhibitor response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001290" ; a owl:Class ; rdfs:label "acetylcholinesterase inhibitor response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_38462 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_38462 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001291 obo:IAO_0000115 "Animals exhibit variations in actions and responses that occurs predominantly, or only, in individuals that are part of a group, from that observed for animals in a control group." ; oboInOwl:hasNarrowSynonym "social behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001291" ; a owl:Class ; rdfs:label "social behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035176 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035176 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001292 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for cells as a collective unit of the body wall muscle system to carry out their normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "body wall muscle physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001292" ; a owl:Class ; rdfs:label "body wall muscle physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000990, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006804 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006804 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001293 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the larva to carry out its normal metabolic functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasExactSynonym "larval physiology abnormal", "larval physiology variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001293" ; a owl:Class ; rdfs:label "larval physiology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000576, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000023 ] ) ] ] . obo:WBPhenotype_0001294 obo:IAO_0000115 "The most anterior portion of the animal is not aligned with the axis of the body." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001294" ; a owl:Class ; rdfs:label "head bent" ; rdfs:subClassOf obo:WBPhenotype_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000617 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000617 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001295 obo:IAO_0000115 "Any portion of the animal, between the head and the tail, appears distorted, usually due to uncharacteristic winding." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001295" ; a owl:Class ; rdfs:label "body twisted" ; rdfs:subClassOf obo:WBPhenotype_0000072 . obo:WBPhenotype_0001296 obo:IAO_0000115 "Animals fail to respond to the concentration of lannate that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasExactSynonym "methomyl resistant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001296" ; a owl:Class ; rdfs:label "lannate resistant" ; rdfs:subClassOf obo:WBPhenotype_0001289, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6835 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6835 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001297 obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the male tail over time, from its formation to the mature structure, compared to control." ; oboInOwl:hasNarrowSynonym "male tail development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001297" ; a owl:Class ; rdfs:label "male tail development variant" ; rdfs:subClassOf obo:WBPhenotype_0000805 . obo:WBPhenotype_0001298 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of the more posterior portion of the intestine, just anterior to the sphincter valve, which is subject to squeezing by the somatal-intestinal muscles compared to control animals (Wormatlas)." ; oboInOwl:hasNarrowSynonym "hindgut morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001298" ; a owl:Class ; rdfs:label "hindgut morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000710 . obo:WBPhenotype_0001299 obo:IAO_0000115 "Any variation that alters the physical partitioning and separation of a cell into daughter cells in male animals compared to control." ; oboInOwl:hasNarrowSynonym "cell division abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001299" ; a owl:Class ; rdfs:label "cell division variant male" ; rdfs:subClassOf obo:WBPhenotype_0000746 . obo:WBPhenotype_0001300 obo:IAO_0000115 "Any variation in the composition or structure of the contents within a germ cell, excluding the plasma membrane and nucleus, compared to control. Germ cells include sperm, oocytes, and their precursors." ; oboInOwl:hasNarrowSynonym "germ cell cytoplasmic morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001300" ; a owl:Class ; rdfs:label "germ cell cytoplasmic morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000900, obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:WBbt_0006796 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0005737 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:WBbt_0006796 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001301 obo:IAO_0000115 "Localization or structural appearance of P-granules is altered compared to control. P-granules are cytoplasmic structures associated with germ nuclei in the C. elegans gonad, and are localized exclusively to germ cells, or germ cell precursors, throughout the life cycle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001301" ; a owl:Class ; rdfs:label "P granule abnormal" ; rdfs:subClassOf obo:WBPhenotype_0001300, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043186 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043186 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001302 obo:IAO_0000115 "The restricted localization of P granules to germ cells or germ cell precursors is altered compared to control." ; oboInOwl:hasNarrowSynonym "P granule localization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "germ granule localization defective" ; oboInOwl:id "WBPhenotype:0001302" ; a owl:Class ; rdfs:label "P granule localization defective" ; rdfs:subClassOf obo:WBPhenotype_0001301 . obo:WBPhenotype_0001303 obo:IAO_0000115 "Animals have one or more extra cells of a particular type, which are present in places they are normally not found, when compared to the number and location of these cells in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001303" ; a owl:Class ; rdfs:label "extra and ectopic cell" ; rdfs:subClassOf obo:WBPhenotype_0002175, obo:WBPhenotype_0002493 . obo:WBPhenotype_0001304 obo:IAO_0000115 "The terminal portion of the intestine exhibits structural defects such as scarring or blockage." ; oboInOwl:hasBroadSynonym "Scar" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001304" ; a owl:Class ; rdfs:label "hindgut damaged" ; rdfs:subClassOf obo:WBPhenotype_0001298 . obo:WBPhenotype_0001305 obo:IAO_0000115 "Any variation in the form or composition of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating." ; oboInOwl:hasNarrowSynonym "hook morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001305" ; a owl:Class ; rdfs:label "hook morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000070, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008425 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008425 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001306 obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the male reproductive system compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." ; oboInOwl:hasNarrowSynonym "male reproductive system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001306" ; a owl:Class ; rdfs:label "male reproductive system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000605, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005747 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005747 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001307 obo:IAO_0000115 "The maximum ventral and dorsal flex of the animal is reduced compared to that observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001307" ; a owl:Class ; rdfs:label "reduced body bend" ; rdfs:subClassOf obo:WBPhenotype_0001703 . obo:WBPhenotype_0001308 obo:IAO_0000115 "The contraction and relaxation movements of the pharyngeal muscle that mediate feeding is not as robust as compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001308" ; a owl:Class ; rdfs:label "weak pumping" ; rdfs:subClassOf obo:WBPhenotype_0000634 . obo:WBPhenotype_0001309 obo:IAO_0000115 "Animals exhibit a decrease in the extent of a vibratory movement (as a worm bend) measured from the mean position to an extreme position compared to control." ; oboInOwl:hasAlternativeId "WBPhenotype:0000003" ; oboInOwl:hasExactSynonym "amplitude of body bends decreased", "flat locomotion path", "flattened locomotion path" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001309" ; a owl:Class ; rdfs:label "amplitude of sinusoidal movement decreased" ; rdfs:subClassOf obo:WBPhenotype_0004022 . obo:WBPhenotype_0001310 obo:IAO_0000115 "The placement of neuronal cells, as a whole or of a specific class of neuron in the animal, deviates from that observed in control animals." ; oboInOwl:hasNarrowSynonym "neuron positioning abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001310" ; a owl:Class ; rdfs:label "neuron positioning variant" ; rdfs:subClassOf obo:WBPhenotype_0000604, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001311 obo:IAO_0000115 "Variations that result in a decrease in protein expression in hermaphrodites compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001311" ; a owl:Class ; rdfs:label "protein expression reduced hermaphrodite" ; rdfs:subClassOf obo:WBPhenotype_0000120 . obo:WBPhenotype_0001312 obo:IAO_0000115 "The quantity of neuronal cells, as a whole or of a specific class of neuron in the animal deviates from that observed in control animals." ; oboInOwl:hasNarrowSynonym "neuron number abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001312" ; a owl:Class ; rdfs:label "neuron number variant" ; rdfs:subClassOf obo:WBPhenotype_0000604, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003679 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001313 obo:IAO_0000115 "Any variation in the progression of the sex-specific muscles of the hermaphrodite, over time, whose contractions squeeze on the uterus to help move eggs towards the vulval opening compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "uterine muscle abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001313" ; a owl:Class ; rdfs:label "uterine muscle variant" ; rdfs:subClassOf obo:WBPhenotype_0000282, obo:WBPhenotype_0002551, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0005342 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0005342 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001314 obo:IAO_0000115 "Any variation in the progression of the sex-specific muscles in the hermaphrodite, over time, that are specialized for egg-laying compared to control. In C. elegans the contractions of the vulval muscles open the lips of the vulva to help in expelling an egg from the uterus (Wormatlas)." ; oboInOwl:hasNarrowSynonym "vulval muscle abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001314" ; a owl:Class ; rdfs:label "vulval muscle variant" ; rdfs:subClassOf obo:WBPhenotype_0000282, obo:WBPhenotype_0002551, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0005821 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0005821 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001315 obo:IAO_0000115 "Animals exhibit variations in the electrical properties of any of its cells or tissues compared to control." ; oboInOwl:hasExactSynonym "electrophysiology abnormal", "electrophysiology variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001315" ; a owl:Class ; rdfs:label "electrophysiology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000519 . obo:WBPhenotype_0001316 obo:IAO_0000115 "Variations in the synaptic currents that are elicited by firing an action potential in a population of axons, compared to control." ; oboInOwl:hasNarrowSynonym "evoked postsynaptic current abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001316" ; a owl:Class ; rdfs:label "evoked postsynaptic current variant" ; rdfs:subClassOf obo:WBPhenotype_0002014 . obo:WBPhenotype_0001317 obo:IAO_0000115 "The amplitudes of synaptic currents that are elicited by firing an action potential in a population of axons are decreased, compared to those observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001317" ; a owl:Class ; rdfs:label "evoked postsynaptic amplitude reduced" ; rdfs:subClassOf obo:WBPhenotype_0001316 . obo:WBPhenotype_0001318 obo:IAO_0000115 "Any variation in the currents observed in the absence of presynaptic action potentials and that are elicited by fusion of a single endogenous vesicle of transmitter compared to control." ; oboInOwl:hasNarrowSynonym "endogenous synaptic events abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001318" ; a owl:Class ; rdfs:label "endogenous synaptic events variant" ; rdfs:subClassOf obo:WBPhenotype_0002014 . obo:WBPhenotype_0001319 obo:IAO_0000115 "The rate (frequency) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is decreased compared to control. Changes in frequency are indicative of presynaptic modifications." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001319" ; a owl:Class ; rdfs:label "endogenous synaptic event frequency reduced" ; rdfs:subClassOf obo:WBPhenotype_0001318 . obo:WBPhenotype_0001320 obo:IAO_0000115 "The amplitude (magnitude) of currents elicited by fusion of a single endogenous vesicle of transmitter in the absence of presynaptic action potentials is altered compared to control. Changes in amplitude are often interpreted as alterations of postsynaptic responsiveness to the transmitter." ; oboInOwl:hasNarrowSynonym "endogenous synaptic amplitude abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001320" ; a owl:Class ; rdfs:label "endogenous synaptic amplitude variant" ; rdfs:subClassOf obo:WBPhenotype_0001318 . obo:WBPhenotype_0001321 obo:IAO_0000115 "Animals display variations in the structure, configuration, distribution or ratio of the components of the vesicle-filled varicosities of the synapse compared to control." ; oboInOwl:hasNarrowSynonym "presynaptic region morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001321" ; a owl:Class ; rdfs:label "presynaptic region morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000616 . obo:WBPhenotype_0001322 obo:IAO_0000115 "OBSOLETE. Total presynaptic vesicle number is reduced, possibly refecting a defect in the replenishment of synaptic vesicles compared to control." ; obo:IAO_0100001 obo:WBPhenotype_0001670 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001322" ; a owl:Class ; rdfs:comment "Electron microscopic analysis." ; rdfs:label "obsolete vesicle number reduced" ; owl:deprecated true . obo:WBPhenotype_0001323 obo:IAO_0000115 "Animals display variations in the shape or size of their vesicles, which are spherical, membrane-bound fluid-filled organelles, compared to vesicles observed in control animals." ; oboInOwl:hasNarrowSynonym "vesicle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001323" ; a owl:Class ; rdfs:comment "Electron microscopic analysis." ; rdfs:label "vesicle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001671, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031982 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031982 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001324 obo:IAO_0000115 "Cells exhibit variations in their response to ionizing radiation compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "cell ionizing radiation response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001324" ; a owl:Class ; rdfs:label "cell ionizing radiation response variant" ; rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0000686, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0071479 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0071479 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001325 obo:IAO_0000115 "Animals initiate but do not continue backward movement, similar to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001325" ; a owl:Class ; rdfs:label "backing not sustained" ; rdfs:subClassOf obo:WBPhenotype_0001005, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001570 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0043057 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001570 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0043057 ] ) ] ] . obo:WBPhenotype_0001326 obo:IAO_0000115 "Cells exhibit variations in their response to gamma ray radiation compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "cell gamma ray response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001326" ; a owl:Class ; rdfs:label "cell gamma ray response variant" ; rdfs:subClassOf obo:WBPhenotype_0000497, obo:WBPhenotype_0001324, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0071480 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0071480 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001327 obo:IAO_0000115 "Cells respond to a lower dosage of gamma rays or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001327" ; a owl:Class ; rdfs:label "cell gamma ray hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001326 . obo:WBPhenotype_0001328 obo:IAO_0000115 "The posterior part of the worm is shorter and stouter compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001328" ; a owl:Class ; rdfs:label "posterior body dumpy" ; rdfs:subClassOf obo:WBPhenotype_0000793 . obo:WBPhenotype_0001329 obo:IAO_0000115 "Animals exhibit a greater number of bends in their body compared to control. C. elegans posture assumes more than a single sine wave." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001329" ; a owl:Class ; rdfs:label "curly" ; rdfs:subClassOf obo:WBPhenotype_0000001 . obo:WBPhenotype_0001330 obo:IAO_0000115 "The rate of the intrinsic behavioral program that serves to move fertilized eggs down the uterus, through the vulva, and out of the worm onto the substrate is reduced compared to that observed in control animals (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "egg laying event rare" ; oboInOwl:id "WBPhenotype:0001330" ; a owl:Class ; rdfs:label "egg laying event infrequent" ; rdfs:subClassOf obo:WBPhenotype_0000006, obo:WBPhenotype_0000272, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001331 obo:IAO_0000115 "Animals display variations in the structure or organization of components of the motor neuron, internal to the cell itself or in relation to the cellular environment compared to that observed in control animals. A motor neuron is a neuronal cell that synapses to an effector (muscle, gland etc.)." ; oboInOwl:hasNarrowSynonym "motor neuron morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001331" ; a owl:Class ; rdfs:comment "WBbt:0005409." ; rdfs:label "motor neuron morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000905, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005409 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005409 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001332 obo:IAO_0000115 "Animals display variations in the number of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "vesicle number abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001332" ; a owl:Class ; rdfs:label "vesicle number variant" ; rdfs:subClassOf obo:WBPhenotype_0001671, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031982 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031982 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001333 obo:IAO_0000115 "The body of a neuron is not where it should be when compared to control animals; it is absent or misplaced." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001333" ; a owl:Class ; rdfs:label "neuron cell body absent misplaced" ; rdfs:subClassOf obo:WBPhenotype_0000816 . obo:WBPhenotype_0001334 obo:IAO_0000115 "Any variation in the form, structure or composition of the muscles of the adult hermaphrodite reproductive system compared to control. In C. elegans hermaphrodites these muscles include the vulval and uterine muscles, located near the vulva in the midbody, which all derive from the M myoblast (Wormatlas)." ; oboInOwl:hasNarrowSynonym "hermaphrodite sex muscle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001334" ; a owl:Class ; rdfs:label "hermaphrodite sex muscle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001335 . obo:WBPhenotype_0001335 obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the hermaphrodite reproductive system, compared to control. The reproductive system is involved in the generation of progeny which contain genetic material inherited from the parents." ; oboInOwl:hasNarrowSynonym "hermaphrodite reproductive system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001335" ; a owl:Class ; rdfs:label "hermaphrodite reproductive system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000605, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005747 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007849 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005747 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007849 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001336 obo:IAO_0000115 "Males sire no cross progeny." ; oboInOwl:hasExactSynonym "no male progeny" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001336" ; a owl:Class ; rdfs:label "male mating efficiency eliminated" ; rdfs:subClassOf obo:WBPhenotype_0000843 . obo:WBPhenotype_0001337 obo:IAO_0000115 "Animals exhibit variations in their response to a specific adrenergic receptor antagonist compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "adrenergic receptor antagonist response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001337" ; a owl:Class ; rdfs:label "adrenergic receptor antagonist response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0001338 obo:IAO_0000115 "Animals fail to respond to the concentration of phentolamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001338" ; a owl:Class ; rdfs:label "phentolamine resistant" ; rdfs:subClassOf obo:WBPhenotype_0001337, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_8081 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_8081 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001339 obo:IAO_0000115 "Animals are not induced to lay eggs in reponse to exogenous levamisole. In C. elegans, levamisole stimulates egg-laying." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001339" ; a owl:Class ; rdfs:label "egg laying levamisole resistant" ; rdfs:subClassOf obo:WBPhenotype_0000421, obo:WBPhenotype_0001101 . obo:WBPhenotype_0001340 obo:IAO_0000115 "Animals are not induced to lay eggs in reponse to exogenous imipramine. In C. elegans, imipramine stimulates egg-laying." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001340" ; a owl:Class ; rdfs:label "egg laying imipramine resistant" ; rdfs:subClassOf obo:WBPhenotype_0000340, obo:WBPhenotype_0001101, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001552 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_47499 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001552 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_47499 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] . obo:WBPhenotype_0001341 obo:IAO_0000115 "Animals are not induced to lay eggs in reponse to exogenous phentolamine. In C. elegans, phentolamine stimulates egg-laying." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001341" ; a owl:Class ; rdfs:label "egg laying phentolamine resistant" ; rdfs:subClassOf obo:WBPhenotype_0001101, obo:WBPhenotype_0001338 . obo:WBPhenotype_0001342 obo:IAO_0000115 "Animals respond to exogenous imipramine at a lower concentration or within a shorter time period than control animals under the same conditions." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001342" ; a owl:Class ; rdfs:label "egg laying imipramine hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001101, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001551 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_47499 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001551 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_47499 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] . obo:WBPhenotype_0001343 obo:IAO_0000115 "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle during a meiotic cell cycle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001343" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "meiotic spindle defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0000759, obo:WBPhenotype_0001868 . obo:WBPhenotype_0001344 obo:IAO_0000115 "Intracellular membrane bound compartments vary in shape or size from that observed in control animals." ; oboInOwl:hasNarrowSynonym "organelle organization biogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001344" ; a owl:Class ; rdfs:label "organelle organization biogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0010002 . obo:WBPhenotype_0001345 obo:IAO_0000115 "Animals exhibit variations in the form, structure, composition or arrangement of any of the various filamentous elements that form the internal framework of cells, compared to control. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles." ; oboInOwl:hasNarrowSynonym "cytoskeleton organization biogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001345" ; a owl:Class ; rdfs:label "cytoskeleton organization biogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000519, obo:WBPhenotype_0001344, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007010 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007010 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001346 obo:IAO_0000115 "Any variation in the dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins compared to control." ; oboInOwl:hasExactSynonym "actin cytoskeleton dynamics variant" ; oboInOwl:hasNarrowSynonym "actin cytoskeleton dynamic abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001346" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "actin cytoskeleton dynamics phenotype" ; rdfs:subClassOf obo:WBPhenotype_0001587 . obo:WBPhenotype_0001347 obo:IAO_0000115 "Any variation in the series of molecular signals in which an intestinal cell uses calcium ions to convert an extracellular signal into a response, compared to control." ; oboInOwl:hasNarrowSynonym "intestinal calcium signaling abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001347" ; a owl:Class ; rdfs:label "intestinal calcium signaling variant" ; rdfs:subClassOf obo:WBPhenotype_0001093, obo:WBPhenotype_0002170 . obo:WBPhenotype_0001348 obo:IAO_0000115 "Variations in the form or composition of a structure in the cell nucleus which contains the genetic material encoded as DNA and surrounded by histone proteins and other regulatory elements compared to control. In C. elegans the normal cell contains 5 pairs of 'autosomes' and one or two X chromosomes (Wormatlas)." ; oboInOwl:hasNarrowSynonym "chromosome morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001348" ; a owl:Class ; rdfs:label "chromosome morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005694 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005694 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001349 obo:IAO_0000115 "Variations in the processes that incorporate phosphate groups to one or more amino acids within a protein, compared to control." ; oboInOwl:hasNarrowSynonym "protein phosphorylation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001349" ; a owl:Class ; rdfs:label "protein phosphorylation variant" ; rdfs:subClassOf obo:WBPhenotype_0001382, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006468 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006468 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001350 obo:IAO_0000115 "Animals exhibit higher levels of protein phosphorylation compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001350" ; a owl:Class ; rdfs:label "protein phosphorylation increased" ; rdfs:subClassOf obo:WBPhenotype_0001349, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006468 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006468 ] ) ] ] . obo:WBPhenotype_0001351 obo:IAO_0000115 "Animals exhibit decreased levels of protein phosphorylation compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001351" ; a owl:Class ; rdfs:label "protein phosphorylation reduced" ; rdfs:subClassOf obo:WBPhenotype_0001349, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006468 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006468 ] ) ] ] . obo:WBPhenotype_0001352 obo:IAO_0000115 "Variations in the chemical reactions and pathways of the endoplasmic reticulum compared to control." ; oboInOwl:hasNarrowSynonym "endoplasmic reticulum metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "er metabolism abnormal" ; oboInOwl:id "WBPhenotype:0001352" ; a owl:Class ; rdfs:label "endoplasmic reticulum metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0001283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005783 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008152 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:GO_0005783 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001353 obo:IAO_0000115 "The coordinated movement during prophase of the two centrosomes and the two pronuclei towards the center of the one cell embryo is abolished." ; oboInOwl:hasNarrowSynonym "centration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001353" ; a owl:Class ; rdfs:label "centration defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001152 . obo:WBPhenotype_0001354 obo:IAO_0000115 "Animals exhibit variations in the form, structure, composition or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas)." ; oboInOwl:hasExactSynonym "actin cytoskeleton filament morphology abnormal", "actin cytoskeleton filament morphology variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001354" ; a owl:Class ; rdfs:label "actin cytoskeleton filament morphology phenotype" ; rdfs:subClassOf obo:WBPhenotype_0001587, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005884 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005884 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001355 obo:IAO_0000115 "Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "gonad morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001355" ; a owl:Class ; rdfs:label "gonad morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000605, obo:WBPhenotype_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005175 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005175 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001356 obo:IAO_0000115 "Any variation in the form, structure or composition of the muscles of the adult male reproductive system compared to control. In C. elegans males, the M myoblast gives rise to a much larger set of specialized muscles, compared to hermaphrodites, which differentiate within the tail region (Wormatlas)." ; oboInOwl:hasNarrowSynonym "male sex muscle morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001356" ; a owl:Class ; rdfs:label "male sex muscle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001024 . obo:WBPhenotype_0001357 obo:IAO_0000115 "Variations in the form or composition of a specialized tissue of the reproductive tract that produces the male gametes compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "male gonad morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001357" ; a owl:Class ; rdfs:label "male gonad morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001024, obo:WBPhenotype_0001355, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001358 obo:IAO_0000115 "Male animals exhibit variations in the structure or organization of any component that is part of the complement of organ tissues that serve to detect, relay and coordinate information about an animal's internal and external environments and to initiate and integrate its effector responses and activities, compared to that in control animals." ; oboInOwl:hasNarrowSynonym "male nervous system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001358" ; a owl:Class ; rdfs:label "male nervous system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000604, obo:WBPhenotype_0001024, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005735 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005735 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007850 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001359 obo:IAO_0000115 "Animals exhibit variations in the structure and organization of the chamber in the male tail that extends from the termination of four canals (vas deferens, gut, and left and right spicule channels) to just before the cloaca, from that observed in control animals." ; oboInOwl:hasNarrowSynonym "proctodeum morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001359" ; a owl:Class ; rdfs:label "proctodeum morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000070, obo:WBPhenotype_0000910, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006795 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006795 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001360 obo:IAO_0000115 "Hermaphrodites fail to produce any viable progeny via self-fertilization. However, such hermaphrodites can successfully reproduce if mated to control males." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001360" ; a owl:Class ; rdfs:label "hermaphrodite self sterile" ; rdfs:subClassOf obo:WBPhenotype_0000694 . obo:WBPhenotype_0001361 obo:IAO_0000115 "Any variation in the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells compared to control." ; oboInOwl:hasNarrowSynonym "chromosome condensation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001361" ; a owl:Class ; rdfs:label "chromosome condensation variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030261 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030261 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001362 obo:IAO_0000115 "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis in eukaryotic cells is abolished." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001362" ; a owl:Class ; rdfs:label "chromosome condensation failure" ; rdfs:subClassOf obo:WBPhenotype_0001361, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030261 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030261 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001363 obo:IAO_0000115 "The head contains cavities, possibly indicative of inappropriate cell death." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "head vacuole" ; oboInOwl:id "WBPhenotype:0001363" ; a owl:Class ; rdfs:label "head cavity" ; rdfs:subClassOf obo:WBPhenotype_0000071, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002112 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002112 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005739 ] ) ] ] . obo:WBPhenotype_0001364 obo:IAO_0000115 "Any variation in the form, structure or composition of the flattened structure extending laterally at the extreme tip of the adult male consisting of nine pairs of sensory rays that lie within a web-like cuticle compared to control." ; oboInOwl:hasNarrowSynonym "male fan morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001364" ; a owl:Class ; rdfs:label "male fan morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000070 . obo:WBPhenotype_0001365 obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the male bursa over time, from its formation to the mature structure, compared to control. The male bursa consists of the lateral fan and rays (WormAtlas)." ; oboInOwl:hasNarrowSynonym "male bursa development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001365" ; a owl:Class ; rdfs:label "male bursa development variant" ; rdfs:subClassOf obo:WBPhenotype_0001297 . obo:WBPhenotype_0001366 obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the male fan over time, from its formation to the mature structure, compared to control." ; oboInOwl:hasNarrowSynonym "male fan development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001366" ; a owl:Class ; rdfs:label "male fan development variant" ; rdfs:subClassOf obo:WBPhenotype_0001365 . obo:WBPhenotype_0001367 obo:IAO_0000115 "Any variation in the process whose specific outcome is the progression of the male proctodeum over time, from its formation to the mature structure, compared to control. The union of the vas deferens and the intestine give rise to the proctodeum which contains copulatory spicules." ; oboInOwl:hasNarrowSynonym "proctodeum development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001367" ; a owl:Class ; rdfs:label "proctodeum development variant" ; rdfs:subClassOf obo:WBPhenotype_0000347, obo:WBPhenotype_0000930, obo:WBPhenotype_0001297, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006795 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006795 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001368 obo:IAO_0000115 "Animals lack the somatic gonad structure that connects the distal gonad arm to the uterus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001368" ; a owl:Class ; rdfs:label "spermatheca absent" ; rdfs:subClassOf obo:WBPhenotype_0001662, obo:WBPhenotype_0002551, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005319 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005319 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001369 obo:IAO_0000115 "Variations in the selective and non-covalent physical association between two or more proteins, or a protein and nucleic acid/macromolecular complex, compared to control." ; oboInOwl:hasNarrowSynonym "protein interaction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001369" ; a owl:Class ; rdfs:label "protein interaction variant" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0065003 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0065003 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001370 obo:IAO_0000115 "Variations in the selective and non-covalent physical association between two or more proteins, compared to control." ; oboInOwl:hasNarrowSynonym "protein protein interaction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001370" ; a owl:Class ; rdfs:label "protein protein interaction variant" ; rdfs:subClassOf obo:WBPhenotype_0001369 . obo:WBPhenotype_0001371 obo:IAO_0000115 "Variations in the selective and non-covalent physical association between a protein and a specific RNA sequence, compared to control." ; oboInOwl:hasNarrowSynonym "protein RNA interaction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001371" ; a owl:Class ; rdfs:label "protein RNA interaction variant" ; rdfs:subClassOf obo:WBPhenotype_0001369, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0022618 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0022618 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001372 obo:IAO_0000115 "Variations in the selective and non-covalent physical association between a protein and a specific DNA sequence, compared to control." ; oboInOwl:hasNarrowSynonym "protein DNA interaction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001372" ; a owl:Class ; rdfs:label "protein DNA interaction variant" ; rdfs:subClassOf obo:WBPhenotype_0001369, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0065004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0065004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001373 obo:IAO_0000115 "Animals lack a specific protein-RNA interaction observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001373" ; a owl:Class ; rdfs:label "protein RNA interaction abolished" ; rdfs:subClassOf obo:WBPhenotype_0001371, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0022618 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0022618 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001374 obo:IAO_0000115 "The shape and size of nuclei as well as the distribution of nucleoporins are strongly affected." ; oboInOwl:hasNarrowSynonym "pronuclear nuclear appearance abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Pna" ; oboInOwl:id "WBPhenotype:0001374" ; a owl:Class ; rdfs:label "pronuclear nuclear appearance variant emb" ; rdfs:subClassOf obo:WBPhenotype_0000764 . obo:WBPhenotype_0001375 obo:IAO_0000115 "The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001375" ; a owl:Class ; rdfs:label "transgene expression undetectable" ; rdfs:subClassOf obo:WBPhenotype_0001278 . obo:WBPhenotype_0001376 obo:IAO_0000115 "The expression of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism is reduced below the threshold of detection in specific cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001376" ; a owl:Class ; rdfs:label "transgene expression undetectable cell specific" ; rdfs:subClassOf obo:WBPhenotype_0001375 . obo:WBPhenotype_0001377 obo:IAO_0000115 "Variations in the generation of foci that mark crossover recombination events, compared to control. These foci mark the boundary of asymmetric synaptonemal complex disassembly." ; oboInOwl:hasNarrowSynonym "break induced focus formation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001377" ; a owl:Class ; rdfs:label "break induced focus formation variant" ; rdfs:subClassOf obo:WBPhenotype_0001256, obo:WBPhenotype_0001324 . obo:WBPhenotype_0001378 obo:IAO_0000115 "Any variation in the cell cycle process whereby replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle compared to control animals." ; oboInOwl:hasNarrowSynonym "mitotic chromosome segregation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001378" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "mitotic chromosome segregation variant" ; rdfs:subClassOf obo:WBPhenotype_0000773, obo:WBPhenotype_0001743, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000070 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000070 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001379 obo:IAO_0000115 "Animals exhibit variations in their response to a specific toxic chemical compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "organism toxic chemical response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001379" ; a owl:Class ; rdfs:label "organism toxic chemical response variant" ; rdfs:subClassOf obo:WBPhenotype_0000523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009636 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009636 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001380 obo:IAO_0000115 "Animals respond to anoxic (trace oxygen levels) stress after a shorter exposure time compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001380" ; a owl:Class ; rdfs:label "anoxia hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0002424 . obo:WBPhenotype_0001381 obo:IAO_0000115 "Animals fail to respond to trace amounts of oxygen that elicit a response in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001381" ; a owl:Class ; rdfs:label "anoxia resistant" ; rdfs:subClassOf obo:WBPhenotype_0002424 . obo:WBPhenotype_0001382 obo:IAO_0000115 "Variations in the covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications), compared to control. This includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification)." ; oboInOwl:hasNarrowSynonym "protein modification abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001382" ; a owl:Class ; rdfs:label "protein modification variant" ; rdfs:subClassOf obo:WBPhenotype_0000112, obo:WBPhenotype_0001644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0036211 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0036211 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001383 obo:IAO_0000115 "Variations in the processes that incorporate methyl groups to one or more amino acids within a protein, compared to control." ; oboInOwl:hasNarrowSynonym "protein methylation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001383" ; a owl:Class ; rdfs:label "protein methylation variant" ; rdfs:subClassOf obo:WBPhenotype_0001382, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006479 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006479 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001384 obo:IAO_0000115 "Animals exhibit a reduction in the production of new individuals that contain some portion of their genetic material inherited from that organism as a result of defective gametes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001384" ; a owl:Class ; rdfs:label "fertility reduced" ; rdfs:subClassOf obo:WBPhenotype_0000145, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001834 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001834 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] ) ] ] . obo:WBPhenotype_0001385 obo:IAO_0000115 "Relatively unspecialized germ cells prematurely acquire the specialized properties of mature oocytes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001385" ; a owl:Class ; rdfs:label "precocious oogenesis" ; rdfs:subClassOf obo:WBPhenotype_0000186, obo:WBPhenotype_0000439, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048477 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048477 ] ) ] ] . obo:WBPhenotype_0001386 obo:IAO_0000115 "Any perturbation that disrupts the fusion of male and female gametes (sperm and oocyte) in adult hermaphrodites during sexual reproduction." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001386" ; a owl:Class ; rdfs:label "fertilization defective hermaphrodite" ; rdfs:subClassOf obo:WBPhenotype_0000983 . obo:WBPhenotype_0001387 obo:IAO_0000115 "Failure of male-derived sperm to fuse with an oocyte during sexual reproduction." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001387" ; a owl:Class ; rdfs:label "fertilization defect male" ; rdfs:subClassOf obo:WBPhenotype_0000983, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009566 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009566 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] . obo:WBPhenotype_0001388 obo:IAO_0000115 "Organisms respond to a lower dosage of gamma rays or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001388" ; a owl:Class ; rdfs:label "organism hypersensitive gamma irradiation" ; rdfs:subClassOf obo:WBPhenotype_0000497, obo:WBPhenotype_0000711 . obo:WBPhenotype_0001389 obo:IAO_0000115 "Cells fail to respond to the dosage of gamma irradiation that elicits a response in control animals. Alternatively, cells require longer exposure times to gamma irradiation to mimic the response observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001389" ; a owl:Class ; rdfs:label "cell gamma ray resistant" ; rdfs:subClassOf obo:WBPhenotype_0001326 . obo:WBPhenotype_0001390 obo:IAO_0000115 "Cells respond to a lower dosage of UV or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001390" ; a owl:Class ; rdfs:label "cell UV hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000100 . obo:WBPhenotype_0001391 obo:IAO_0000115 "Animals exhibit an increase in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001391" ; a owl:Class ; rdfs:label "gamma ray induced apoptosis increased" ; rdfs:subClassOf obo:WBPhenotype_0000183, obo:WBPhenotype_0001326 . obo:WBPhenotype_0001392 obo:IAO_0000115 "Cells of the animals cease during one of its replicative phases (G1, S, G2, M)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001392" ; a owl:Class ; rdfs:label "cell cycle arrest" ; rdfs:subClassOf obo:WBPhenotype_0001995, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007049 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000297 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007049 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001393 obo:IAO_0000115 "Variations in the processes that reduce the internal pH of a cell (measured by the concentration of the hydrogen ion), compared to control." ; oboInOwl:hasNarrowSynonym "cell acidification abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001393" ; a owl:Class ; rdfs:label "cell acidification variant" ; rdfs:subClassOf obo:WBPhenotype_0000585, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051452 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051452 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001394 obo:IAO_0000115 "Animals lack the capacity to reduce the internal pH of a cell." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "no pumping" ; oboInOwl:id "WBPhenotype:0001394" ; a owl:Class ; rdfs:label "cell acidification defective" ; rdfs:subClassOf obo:WBPhenotype_0001393, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001624 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051452 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001624 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051452 ] ) ] ] . obo:WBPhenotype_0001395 obo:IAO_0000115 "Vacuoles accumulate in the body. A vacuole is a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001395" ; a owl:Class ; rdfs:label "body vacuole" ; rdfs:subClassOf obo:WBPhenotype_0000072, obo:WBPhenotype_0002615 . obo:WBPhenotype_0001396 obo:IAO_0000115 "Animals completely lack any pharyngeal pumping motion." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001396" ; a owl:Class ; rdfs:label "pumping absent" ; rdfs:subClassOf obo:WBPhenotype_0001006, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001397 obo:IAO_0000115 "Animals exhibit an increase in the cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001397" ; a owl:Class ; rdfs:label "necrotic cell death increased" ; rdfs:subClassOf obo:WBPhenotype_0000415, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0070265 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0070265 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001398 obo:IAO_0000115 "Animals display variations in the structure, organization of components, or spatial pattern of any projection stemming from a neuronal cell, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "neurite morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001398" ; a owl:Class ; rdfs:label "neurite morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000905, obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043005 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043005 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001399 obo:IAO_0000115 "Any variation in the structure, form or composition of the semipermeable lipid bilayer that creates a boundary between the interior and exterior environment for cells, cellular organelles and tissues, within an organism compared to control." ; oboInOwl:hasNarrowSynonym "cell membrane morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001399" ; a owl:Class ; rdfs:label "cell membrane morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005886 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005886 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001400 obo:IAO_0000115 "Animals exhibit variations in the measured expression of a protein compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "level of protein expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001400" ; a owl:Class ; rdfs:label "level of protein expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000112 . obo:WBPhenotype_0001401 obo:IAO_0000115 "The morphological appearance of mitochondria is varied compared to control animals." ; oboInOwl:hasExactSynonym "mitochondria morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001401" ; a owl:Class ; rdfs:label "mitochondria morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001402 obo:IAO_0000115 "Mitochondria are interconnected by thin tubules of mitochondrial inner or outer membrane." ; oboInOwl:hasNarrowSynonym "connected mitochodria muscle", "connected mitochondria epithelial" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001402" ; a owl:Class ; rdfs:label "connected mitochondria" ; rdfs:subClassOf obo:WBPhenotype_0001401, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000642 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005739 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000642 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005739 ] ) ] ] . obo:WBPhenotype_0001403 obo:IAO_0000115 "Any variation in the placement of a protein, as detected by antibody staining, within in a cell or cellular compartment compared to control." ; oboInOwl:hasNarrowSynonym "antibody subcellular localization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001403" ; a owl:Class ; rdfs:label "antibody subcellular localization variant" ; rdfs:subClassOf obo:WBPhenotype_0000424 . obo:WBPhenotype_0001404 obo:IAO_0000115 "Any variation that results in the detection of protein expression in cells/tissues through antibody staining, that is otherwise not observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001404" ; a owl:Class ; rdfs:label "ectopic expression antibody" ; rdfs:subClassOf obo:WBPhenotype_0000424 . obo:WBPhenotype_0001405 obo:IAO_0000115 "Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding." ; oboInOwl:hasNarrowSynonym "protein aggregation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001405" ; a owl:Class ; rdfs:label "protein aggregation variant" ; rdfs:subClassOf obo:WBPhenotype_0001370 . obo:WBPhenotype_0001406 obo:IAO_0000115 "Variations that result in a decrease in protein expression in male animals compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001406" ; a owl:Class ; rdfs:label "protein expression reduced male" ; rdfs:subClassOf obo:WBPhenotype_0000120 . obo:WBPhenotype_0001407 obo:IAO_0000115 "Variations that result in a decrease in protein expression in specific cells compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001407" ; a owl:Class ; rdfs:label "protein expression reduced cell specific" ; rdfs:subClassOf obo:WBPhenotype_0000120 . obo:WBPhenotype_0001408 obo:IAO_0000115 "Any variation in the cellular or subcellular distribution of a protein compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "pattern protein expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001408" ; a owl:Class ; rdfs:label "pattern protein expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000112 . obo:WBPhenotype_0001409 obo:IAO_0000115 "Any variation that results in the cellular expression of a protein in cells/tissues, that is otherwise not observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001409" ; a owl:Class ; rdfs:label "protein expression ectopic" ; rdfs:subClassOf obo:WBPhenotype_0001408 . obo:WBPhenotype_0001410 obo:IAO_0000115 "Animals fail to express a given protein or class of proteins." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001410" ; a owl:Class ; rdfs:label "protein expression absent" ; rdfs:subClassOf obo:WBPhenotype_0000120 . obo:WBPhenotype_0001411 obo:IAO_0000115 "Animals exhibit an altered display of glycosylated proteins or lipids or altered access to glycosylated moieties along their surface from that observed in control animals of the same developmental stage. In C. elegans, variations in surface accessible glycosylated species are often revealed by altered lectin-binding from that observed in control animals." ; oboInOwl:hasNarrowSynonym "Srf", "cuticle carbohydrate surface abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ectopic lectin binding" ; oboInOwl:id "WBPhenotype:0001411" ; a owl:Class ; rdfs:label "cuticle carbohydrate surface variant" ; rdfs:subClassOf obo:WBPhenotype_0001210 . obo:WBPhenotype_0001412 obo:IAO_0000115 "Animals exhibit variations in the organization of the longitudinal ridges on the cuticle along the length of the animal, from that observed for control animals of the same developmental stage." ; oboInOwl:hasNarrowSynonym "alae morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001412" ; a owl:Class ; rdfs:label "alae morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000948, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007832 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007832 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001413 obo:IAO_0000115 "Animals do not exhibit tail-swelling in response to infection by a bacterial pathogen (such as Microbacterium nematophilum) compared to control." ; oboInOwl:hasBroadSynonym "Bus" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001413" ; a owl:Class ; rdfs:label "bacterially unswollen" ; rdfs:subClassOf obo:WBPhenotype_0000073, obo:WBPhenotype_0001014, obo:WBPhenotype_0002545 . obo:WBPhenotype_0001414 obo:IAO_0000115 "Males exhibit defects in the specific actions or reactions that are associated with reproduction." ; oboInOwl:hasBroadSynonym "Cod" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001414" ; a owl:Class ; rdfs:label "male mating defective" ; rdfs:subClassOf obo:WBPhenotype_0000648, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060179 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060179 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000056 ] ) ] ] . obo:WBPhenotype_0001415 obo:IAO_0000115 "Animals exhibit variations that result in variations in the ability of or extent to which pathogens adhere to the surface of animals, compared to control." ; oboInOwl:hasNarrowSynonym "pathogen adherence abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001415" ; a owl:Class ; rdfs:label "pathogen adherence variant" ; rdfs:subClassOf obo:WBPhenotype_0001012 . obo:WBPhenotype_0001416 obo:IAO_0000115 "Pathogens are unable to adhere/colonize the surface of host animals. This defect is often associated with changes in cuticle surface properties of the host." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001416" ; a owl:Class ; rdfs:label "pathogen adherence defect" ; rdfs:subClassOf obo:WBPhenotype_0001014, obo:WBPhenotype_0002461 . obo:WBPhenotype_0001417 obo:IAO_0000115 "Any variation in the state or activity of an organism in response to extreme dryness or drought-like conditions, compared to control ." ; oboInOwl:hasNarrowSynonym "organism desication response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001417" ; a owl:Class ; rdfs:label "organism desiccation response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, obo:WBPhenotype_0000523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009269 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009269 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001418 obo:IAO_0000115 "Animals respond to less severe drought-like conditions or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001418" ; a owl:Class ; rdfs:label "organism hypersensitive desiccation" ; rdfs:subClassOf obo:WBPhenotype_0001417 . obo:WBPhenotype_0001419 obo:IAO_0000115 "Animals respond to emetine at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001419" ; a owl:Class ; rdfs:label "emetine hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4781 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4781 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001420 obo:IAO_0000115 "Animals can move thorough a lawn of bacterially produced biofilm without accumulating an enormous amount of biofilm on its nose. When C. elegans is exposed to certain bacteria (e.g., Y. pestis), a biofilm accumulates on a worm's head. The presence of this biofilm inhibits feeding by the worm, and thereby prevents growth." ; oboInOwl:hasBroadSynonym "Bah" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001420" ; a owl:Class ; rdfs:label "biofilm absent head" ; rdfs:subClassOf obo:WBPhenotype_0001415 . obo:WBPhenotype_0001421 obo:IAO_0000115 "Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control." ; oboInOwl:hasNarrowSynonym "endocytic transport abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001421" ; a owl:Class ; rdfs:label "endocytic transport variant" ; rdfs:subClassOf obo:WBPhenotype_0001752, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006897 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006897 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001422 obo:IAO_0000115 "Animals exhibit defects in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001422" ; a owl:Class ; rdfs:label "endocytic transport defect" ; rdfs:subClassOf obo:WBPhenotype_0001421, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006897 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006897 ] ) ] ] . obo:WBPhenotype_0001423 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the coelomocyte to carry out its normal functions or activities, compared to control animals." ; oboInOwl:hasNarrowSynonym "coelomocyte physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001423" ; a owl:Class ; rdfs:label "coelomocyte physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, obo:WBPhenotype_0000607, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005751 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0005751 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001424 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the oocyte to carry out its normal functions or activities, compared to control animals." ; oboInOwl:hasNarrowSynonym "oocyte physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001424" ; a owl:Class ; rdfs:label "oocyte physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000929, obo:WBPhenotype_0000987, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006797 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0008150 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006797 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001425 obo:IAO_0000115 "Animals exhibit defects in the cell-mediated uptake of external materials via receptor activity. Receptor-mediated endocytosis ensures specificity of transport and generally occurs via clathrin-coated pits and vesicles. In C. elegans, this is often judged by the lack of yolk uptake in oocytes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Rme" ; oboInOwl:id "WBPhenotype:0001425" ; a owl:Class ; rdfs:comment "Possible XP = GO:0006898." ; rdfs:label "receptor mediated endocytosis defective" ; rdfs:subClassOf obo:WBPhenotype_0001422, obo:WBPhenotype_0001424, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006898 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006898 ] ) ] ] . obo:WBPhenotype_0001426 obo:IAO_0000115 "Fluid-phase endocytosis by coelomocytes is less frequent or efficient compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Cup" ; oboInOwl:id "WBPhenotype:0001426" ; a owl:Class ; rdfs:label "coelomocyte endocytosis defective" ; rdfs:subClassOf obo:WBPhenotype_0001422, obo:WBPhenotype_0001423 . obo:WBPhenotype_0001427 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of any cellular contents (excluding plasma membrane and nucleus), compared to control animals." ; oboInOwl:hasNarrowSynonym "cytoplasmic appearance abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001427" ; a owl:Class ; rdfs:label "cytoplasmic appearance variant" ; rdfs:subClassOf obo:WBPhenotype_0010002 . obo:WBPhenotype_0001428 obo:IAO_0000115 "Vacuoles accumulate in the intestine." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001428" ; a owl:Class ; rdfs:label "intestinal vacuole" ; rdfs:subClassOf obo:WBPhenotype_0000710, obo:WBPhenotype_0002615 . obo:WBPhenotype_0001429 obo:IAO_0000115 "Animals accumulate an excess of vesicle-like structures in cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001429" ; a owl:Class ; rdfs:label "granules cytoplasm" ; rdfs:subClassOf obo:WBPhenotype_0001427 . obo:WBPhenotype_0001430 obo:IAO_0000115 "Variations in the processes that are carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome, compared to control." ; oboInOwl:hasNarrowSynonym "lysosome organization biogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001430" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "lysosome organization biogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007040 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007040 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001431 obo:IAO_0000115 "Male tails fail to undergo tip retraction thereby forming a 'leptoderan' or 'pointed' adult tail." ; oboInOwl:hasBroadSynonym "Lep" ; oboInOwl:hasExactSynonym "male tail spike" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "leptoderan tail" ; oboInOwl:id "WBPhenotype:0001431" ; a owl:Class ; rdfs:label "pointed tail tip male" ; rdfs:subClassOf obo:WBPhenotype_0000070 . obo:WBPhenotype_0001432 obo:IAO_0000115 "Adult males exhibit a truncated tail, often without a fan or have well-developed fans but squarish, truncated back ends compared to control. In C. elegans this is due to precocious male tail tip retraction beginning in the early L3 stage (normally retraction begins in the L4 stage). Condition can be lethal if the function of the anus is affected." ; oboInOwl:hasBroadSynonym "Ore" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001432" ; a owl:Class ; rdfs:label "over retracted male tail" ; rdfs:subClassOf obo:WBPhenotype_0000070, obo:WBPhenotype_0001297, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001477 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001477 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] ) ] ] . obo:WBPhenotype_0001433 obo:IAO_0000115 "Two or more individual cells form a syncytium (a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane) via the fusion of the plasma membranes at an earlier stage of development compared to comparable cells in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001433" ; a owl:Class ; rdfs:label "precocious cell fusion" ; rdfs:subClassOf obo:WBPhenotype_0000165, obo:WBPhenotype_0000439, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000768 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000768 ] ) ] ] . obo:WBPhenotype_0001434 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific chemical concentration gradient compared to control. Directed movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)." ; oboInOwl:hasNarrowSynonym "chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Che" ; oboInOwl:id "WBPhenotype:0001434" ; a owl:Class ; rdfs:label "chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001040, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006935 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006935 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001435 obo:IAO_0000115 "Failure in directed movement in response to ammonium chloride compared to control. In C. elegans, NH4Cl is an attractant. NH4Cl has also subsequently been used to assay for Cl- attraction in C. elegans." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "chloride chemotaxis defective" ; oboInOwl:id "WBPhenotype:0001435" ; a owl:Class ; rdfs:label "ammonium chloride chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001460, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_31206 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_31206 ] ) ] ] . obo:WBPhenotype_0001436 obo:IAO_0000115 "Animals tend to initiate a response more often, compared to control, after nose-on collisions with an object. In C. elegans, animals initiate backwards movement in response to nose touch." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001436" ; a owl:Class ; rdfs:label "nose touch hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0004026 . obo:WBPhenotype_0001437 obo:IAO_0000115 "Animals execute a response, via directed movement to octanol at a lower concentration or shorter exposure time compared to control. In C. elegans, animals avoid octanol." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001437" ; a owl:Class ; rdfs:label "octanol chemotaxis hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001452 . obo:WBPhenotype_0001438 obo:IAO_0000115 "Animals fail to move towards attractive volatile organic molecules. In C. elegans, these compounds are sensed by the AWA and AWC neurons." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001438" ; a owl:Class ; rdfs:label "odorant positive chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0000015, obo:WBPhenotype_0000265 . obo:WBPhenotype_0001439 obo:IAO_0000115 "Animals fail to move towards attractive anions." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001439" ; a owl:Class ; rdfs:label "anion positive chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001052, obo:WBPhenotype_0001441 . obo:WBPhenotype_0001440 obo:IAO_0000115 "Animals fail to move towards attractive cations." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001440" ; a owl:Class ; rdfs:label "cation positive chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001051, obo:WBPhenotype_0001441 . obo:WBPhenotype_0001441 obo:IAO_0000115 "Animals fail to move towards attractive water-soluble chemicals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "water soluble positive chemotaxis abnormal" ; oboInOwl:id "WBPhenotype:0001441" ; a owl:Class ; rdfs:label "aqueous positive chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0000015, obo:WBPhenotype_0001047 . obo:WBPhenotype_0001442 obo:IAO_0000115 "Failure in directed movement in response to sodium acetate. In C. elegans, sodium acetate is an attractant. Sodium acetate has also subsequently been used to assay for Na+ attraction in C. elegans." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "sodium chemotaxis defective" ; oboInOwl:id "WBPhenotype:0001442" ; a owl:Class ; rdfs:label "sodium acetate chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001441, obo:WBPhenotype_0001461, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_32954 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_32954 ] ) ] ] . obo:WBPhenotype_0001443 obo:IAO_0000115 "Animals exhibit variations in response to water-soluble chemicals, compared to control." ; oboInOwl:hasNarrowSynonym "aqueous chemosensory response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "water soluble chemosensory response abnormal" ; oboInOwl:id "WBPhenotype:0001443" ; a owl:Class ; rdfs:label "aqueous chemosensory response variant" ; rdfs:subClassOf obo:WBPhenotype_0001040 . obo:WBPhenotype_0001444 obo:IAO_0000115 "Animals do not exhibit characteristic desensitization to a water-soluble chemo-attractive signal in a time-concentration dependent and reversible manner compared to control." ; oboInOwl:hasNarrowSynonym "aqueous adaptation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "gustatory plasticity abnormal", "water soluble adaptation abnormal" ; oboInOwl:id "WBPhenotype:0001444" ; a owl:Class ; rdfs:label "aqueous adaptation defective" ; rdfs:subClassOf obo:WBPhenotype_0001443 . obo:WBPhenotype_0001445 obo:IAO_0000115 "Animals do not exhibit characteristic chemoattractive desensitization to sodium acetate in a time-concentration dependent and reversible manner compared to control." ; oboInOwl:hasNarrowSynonym "sodium acetate adaptation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001445" ; a owl:Class ; rdfs:label "sodium acetate adaptation defective" ; rdfs:subClassOf obo:WBPhenotype_0001444 . obo:WBPhenotype_0001446 obo:IAO_0000115 "Animals do not exhibit characteristic chemoattractive desensitization to sodium chloride in a time-concentration dependent and reversible manner compared to control." ; oboInOwl:hasNarrowSynonym "sodium chloride adaptation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001446" ; a owl:Class ; rdfs:label "sodium chloride adaptation defective" ; rdfs:subClassOf obo:WBPhenotype_0001444 . obo:WBPhenotype_0001447 obo:IAO_0000115 "Animals do not exhibit characteristic chemoattractive desensitization to ammonium chloride in a time-concentration dependent and reversible manner compared to control." ; oboInOwl:hasNarrowSynonym "ammonium chloride adaptation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001447" ; a owl:Class ; rdfs:label "ammonium chloride adaptation defective" ; rdfs:subClassOf obo:WBPhenotype_0001444 . obo:WBPhenotype_0001448 obo:IAO_0000115 "Animals fail to move away from repellant volatile organic chemicals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "volatile negative chemotaxis defective" ; oboInOwl:id "WBPhenotype:0001448" ; a owl:Class ; rdfs:label "odorant negative chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001455 . obo:WBPhenotype_0001449 obo:IAO_0000115 "Animals fail to move away from repellent water soluble chemicals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "water soluble chemotaxis defective" ; oboInOwl:id "WBPhenotype:0001449" ; a owl:Class ; rdfs:label "aqueous negative chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001450 . obo:WBPhenotype_0001450 obo:IAO_0000115 "Animals exhibit variations through directed movement, in response to repellant water soluble chemicals, compared to control." ; oboInOwl:hasNarrowSynonym "aqueous negative chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "water soluble chemotaxis abnormal" ; oboInOwl:id "WBPhenotype:0001450" ; a owl:Class ; rdfs:label "aqueous negative chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000481, obo:WBPhenotype_0001443 . obo:WBPhenotype_0001451 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of garlic compared to control. In C. elegans, garlic is typically a repellant." ; oboInOwl:hasNarrowSynonym "garlic chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001451" ; a owl:Class ; rdfs:label "garlic chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001450 . obo:WBPhenotype_0001452 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of octanol. In C. elegans, octanol is typically a repellant." ; oboInOwl:hasNarrowSynonym "octanol chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001452" ; a owl:Class ; rdfs:label "octanol chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001455 . obo:WBPhenotype_0001453 obo:IAO_0000115 "Animals exhibit variations in their avoidance response to high concentrations of sodium chloride solution compared to control." ; oboInOwl:hasNarrowSynonym "high sodium chloride concentration osmotic avoidance abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001453" ; a owl:Class ; rdfs:label "high sodium chloride concentration osmotic avoidance variant" ; rdfs:subClassOf obo:WBPhenotype_0000663 . obo:WBPhenotype_0001454 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of the bitter tastant quinine, a water soluble molecule. In C. elegans, quinine is typically a repellant." ; oboInOwl:hasNarrowSynonym "quinine chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001454" ; a owl:Class ; rdfs:label "quinine chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001939 . obo:WBPhenotype_0001455 obo:IAO_0000115 "Animals exhibit variations through directed movement, in response to repellant volatile organic chemicals, compared to control." ; oboInOwl:hasNarrowSynonym "odorant negative chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "volatile negative chemotaxis abnormal" ; oboInOwl:id "WBPhenotype:0001455" ; a owl:Class ; rdfs:label "odorant negative chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000481, obo:WBPhenotype_0001048 . obo:WBPhenotype_0001456 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of nonanone. In C. elegans, nonanone is typically a repellant." ; oboInOwl:hasNarrowSynonym "nonanone chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001456" ; a owl:Class ; rdfs:label "nonanone chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001455 . obo:WBPhenotype_0001457 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of bromide. In C. elegans, bromide is typically an attractant." ; oboInOwl:hasNarrowSynonym "bromide chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001457" ; a owl:Class ; rdfs:label "bromide chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001052 . obo:WBPhenotype_0001458 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of chloride." ; oboInOwl:hasNarrowSynonym "chloride chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ammonium chloride chemotaxis abnormal" ; oboInOwl:id "WBPhenotype:0001458" ; a owl:Class ; rdfs:label "chloride chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001052 . obo:WBPhenotype_0001459 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of iodide." ; oboInOwl:hasNarrowSynonym "iodide chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001459" ; a owl:Class ; rdfs:label "iodide chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001052 . obo:WBPhenotype_0001460 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of ammonium chloride. In C. elegans, at specific concentrations, ammonium chloride is an attractant. NH4Cl has also been used to assay for Cl- attraction." ; oboInOwl:hasNarrowSynonym "ammonium chloride chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "chloride chemotaxis abnormal" ; oboInOwl:id "WBPhenotype:0001460" ; a owl:Class ; rdfs:label "ammonium chloride chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001047 . obo:WBPhenotype_0001461 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium acetate. In C. elegans, at specific concentrations, sodium acetate is an attractant. Sodium acetate has also been used to assay for Na+ attraction." ; oboInOwl:hasNarrowSynonym "sodium acetate chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "sodium chemotaxis abnormal" ; oboInOwl:id "WBPhenotype:0001461" ; a owl:Class ; rdfs:label "sodium acetate chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001047 . obo:WBPhenotype_0001462 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of sodium chloride. In C. elegans, at specific concentrations, sodium chloride is an attractant." ; oboInOwl:hasNarrowSynonym "sodium chloride chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001462" ; a owl:Class ; rdfs:label "sodium chloride chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001047 . obo:WBPhenotype_0001463 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of cAMP." ; oboInOwl:hasNarrowSynonym "cAMP chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001463" ; a owl:Class ; rdfs:label "cAMP chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001053 . obo:WBPhenotype_0001464 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of cGMP." ; oboInOwl:hasNarrowSynonym "cGMP chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001464" ; a owl:Class ; rdfs:label "cGMP chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001053 . obo:WBPhenotype_0001465 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of acetone. In C. elegans, at specific concentrations, acetone is an attractant." ; oboInOwl:hasNarrowSynonym "acetone chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001465" ; a owl:Class ; rdfs:label "acetone chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000265 . obo:WBPhenotype_0001466 obo:IAO_0000115 "Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWA sensory neuron in control animals." ; oboInOwl:hasNarrowSynonym "AWA odorant chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "AWA volatile chemotaxis abnormal" ; oboInOwl:id "WBPhenotype:0001466" ; a owl:Class ; rdfs:label "AWA odorant chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000265 . obo:WBPhenotype_0001467 obo:IAO_0000115 "Any variation in the directed movement of an animal in response to a volatile chemical stimulus that is usually received and processed by the AWC sensory neuron in control animals." ; oboInOwl:hasNarrowSynonym "AWC odorant chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "AWC volatile chemotaxis abnormal" ; oboInOwl:id "WBPhenotype:0001467" ; a owl:Class ; rdfs:label "AWC odorant chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000265 . obo:WBPhenotype_0001468 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of benzaldehyde. In C. elegans, at specific concentrations, benzaldehyde is an attractant." ; oboInOwl:hasNarrowSynonym "benzaldehyde chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001468" ; a owl:Class ; rdfs:label "benzaldehyde chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001467 . obo:WBPhenotype_0001469 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of butanone. In C. elegans, at specific concentrations, butanone is an attractant." ; oboInOwl:hasNarrowSynonym "butanone chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001469" ; a owl:Class ; rdfs:label "butanone chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001467 . obo:WBPhenotype_0001470 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of diacetyl. In C. elegans, at specific concentrations, diacetyl is an attractant." ; oboInOwl:hasNarrowSynonym "diacetyl chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001470" ; a owl:Class ; rdfs:label "diacetyl chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001466 . obo:WBPhenotype_0001471 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of hexanol. In C. elegans, at specific concentrations, hexanol is an attractant." ; oboInOwl:hasNarrowSynonym "hexanol chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001471" ; a owl:Class ; rdfs:label "hexanol chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000265 . obo:WBPhenotype_0001472 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of isoamyl alcohol. In C. elegans, at specific concentrations, isoamyl alcohol is an attractant." ; oboInOwl:hasNarrowSynonym "isoamyl alcohol chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001472" ; a owl:Class ; rdfs:label "isoamyl alcohol chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001467 . obo:WBPhenotype_0001473 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanol. In C. elegans, at specific concentrations, pentanol is an attractant." ; oboInOwl:hasNarrowSynonym "pentanol chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001473" ; a owl:Class ; rdfs:label "pentanol chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000265 . obo:WBPhenotype_0001474 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of pyrazine. In C. elegans, at specific concentrations, pyrazine is an attractant." ; oboInOwl:hasNarrowSynonym "pyrazine chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001474" ; a owl:Class ; rdfs:label "pyrazine chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001466 . obo:WBPhenotype_0001475 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of trimethylthiazole. In C. elegans, at specific concentrations, trimethylthiazole is an attractant." ; oboInOwl:hasNarrowSynonym "trimethylthiazole chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001475" ; a owl:Class ; rdfs:label "trimethylthiazole chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0000265 . obo:WBPhenotype_0001476 obo:IAO_0000115 "Any variation in the defecation motor program that involves the contraction of the anterior body wall muscles compared to control." ; oboInOwl:hasNarrowSynonym "anterior body contraction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001476" ; a owl:Class ; rdfs:label "anterior body contraction variant" ; rdfs:subClassOf obo:WBPhenotype_0000210 . obo:WBPhenotype_0001477 obo:IAO_0000115 "Any variation in the directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons, compared to control." ; oboInOwl:hasNarrowSynonym "anterograde transport abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001477" ; a owl:Class ; rdfs:label "anterograde transport variant" ; rdfs:subClassOf obo:WBPhenotype_0002563 . obo:WBPhenotype_0001478 obo:IAO_0000115 "Any variation in the elongation of embryonic epidermal cells compared to control. In C. elegans, this elongation occurs along an anterior-posterior axis, which is required to transform the bean-shaped embryo into the elongated shape of the worm." ; oboInOwl:hasNarrowSynonym "body elongation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001478" ; a owl:Class ; rdfs:label "body elongation variant" ; rdfs:subClassOf obo:WBPhenotype_0000749 . obo:WBPhenotype_0001479 obo:IAO_0000115 "Animals exhibit variations in any of a series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal that induces dauer formation in control animals." ; oboInOwl:hasNarrowSynonym "dauer pheromone sensation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001479" ; a owl:Class ; rdfs:label "dauer pheromone sensation variant" ; rdfs:subClassOf obo:WBPhenotype_0000132, obo:WBPhenotype_0000305, obo:WBPhenotype_0001847 . obo:WBPhenotype_0001480 obo:IAO_0000115 "Variations in the rhythmic relaxations of the a highly specialized cuticle region of the pharynx inside the lumen of the second bulb, compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "grinder relaxation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001480" ; a owl:Class ; rdfs:label "grinder relaxation variant" ; rdfs:subClassOf obo:WBPhenotype_0000336 . obo:WBPhenotype_0001481 obo:IAO_0000115 "The number of body thrashes within an aqueous environment in a given period of time is increased, compared with control worms." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001481" ; a owl:Class ; rdfs:label "thrashing increased" ; rdfs:subClassOf obo:WBPhenotype_0001700 . obo:WBPhenotype_0001482 obo:IAO_0000115 "Animals exhibit a reduction in the frequency of oscillations between adjacent body segments from that observed for control animals." ; oboInOwl:hasAlternativeId "WBPhenotype:0002330" ; oboInOwl:hasExactSynonym "bending frequency reduced", "frequency of sinusoidal movement reduced", "temporal frequency of sinusoidal movement decreased" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001482" ; a owl:Class ; rdfs:label "frequency body bend reduced" ; rdfs:subClassOf obo:WBPhenotype_0001213, obo:WBPhenotype_0004023 . obo:WBPhenotype_0001483 obo:IAO_0000115 "The eggs being deposited by adults are of a later developmental stage, compared to control. In C. elegans, this is likely to be a consequence of delayed active egg-laying periods." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001483" ; a owl:Class ; rdfs:label "late stage egg laid" ; rdfs:subClassOf obo:WBPhenotype_0000438, obo:WBPhenotype_0000545 . obo:WBPhenotype_0001484 obo:IAO_0000115 "Animals fail to execute directed movement in response to ammonium acetate. In C. elegans, ammonium acetate is an attractant." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001484" ; a owl:Class ; rdfs:label "ammonium acetate chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0000265, obo:WBPhenotype_0001441 . obo:WBPhenotype_0001485 obo:IAO_0000115 "Animals exhibit variations in their response to the presence of unfolded proteins in the endoplasmic reticulum (ER) or to other ER-related stressors compared to control." ; oboInOwl:hasExactSynonym "ER stress response abnormal", "endoplasmic reticulum stress response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001485" ; a owl:Class ; rdfs:label "ER stress response variant" ; rdfs:subClassOf obo:WBPhenotype_0000142, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034976 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0034976 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001486 obo:IAO_0000115 "Animals accumulate unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001486" ; a owl:Class ; rdfs:label "unfolded protein accumulation" ; rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0001644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030968 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000911 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030968 ] ) ] ] . obo:WBPhenotype_0001487 obo:IAO_0000115 "Animals exhibit variations in the development of the male elongated sclerotized structures covered by a hardened layer of cuticle in the tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) compared to control." ; oboInOwl:hasNarrowSynonym "male spicule development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001487" ; a owl:Class ; rdfs:label "male spicule development variant" ; rdfs:subClassOf obo:WBPhenotype_0000430, obo:WBPhenotype_0000930, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005312 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005312 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001488 obo:IAO_0000115 "Animals exhibit variations in the development of the sclerotic cuticle that forms the roof of the proctodeum (gubernaculum) compared to control." ; oboInOwl:hasNarrowSynonym "gubernaculum development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001488" ; a owl:Class ; rdfs:label "gubernaculum development variant" ; rdfs:subClassOf obo:WBPhenotype_0001367, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0008424 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0008424 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001489 obo:IAO_0000115 "Animals exhibit variations in the structure or composition of the sclerotic cuticle that forms the roof of the proctodeum, from that observed in control animals." ; oboInOwl:hasNarrowSynonym "gubernaculum morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001489" ; a owl:Class ; rdfs:label "gubernaculum morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001359, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008424 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0008424 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001490 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000793 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001490" ; a owl:Class ; rdfs:label "obsolete posterior region morphology abnormal" ; owl:deprecated true . obo:WBPhenotype_0001491 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0000792 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001491" ; a owl:Class ; rdfs:label "obsolete anterior region morphology abnormal" ; owl:deprecated true . obo:WBPhenotype_0001492 obo:IAO_0000115 "Animals lack a properly developed posterior region compared to control. In C. elegans, mutants exhibit a severely deformed posterior region with a variable knob-like shape; accompanied by arrest at about the time of hatching with fairly normal pharyngeal and anterior development. Most mutants arrest as L1 larvae, and 5% do not hatch." ; oboInOwl:hasBroadSynonym "Nob" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001492" ; a owl:Class ; rdfs:label "no back end" ; rdfs:subClassOf obo:WBPhenotype_0000081, obo:WBPhenotype_0000793, obo:WBPhenotype_0000800, obo:WBPhenotype_0000867, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005741 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001493 obo:IAO_0000115 "VPCs (vulval precursor cells) divide at an earlier stage of development compared to control animals; in C. elegans, VPCs divide in the mid-L3 stage to generate the 22 cells that comprise the vulva." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001493" ; a owl:Class ; rdfs:label "VPC cell division precocious" ; rdfs:subClassOf obo:WBPhenotype_0000345, obo:WBPhenotype_0001495, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007809 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:WBbt_0007809 ] ) ] ] . obo:WBPhenotype_0001494 obo:IAO_0000115 "DTCs migrate at an earlier stage of development, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001494" ; a owl:Class ; rdfs:label "distal tip cell migration precocious" ; rdfs:subClassOf obo:WBPhenotype_0000195, obo:WBPhenotype_0000439 . obo:WBPhenotype_0001495 obo:IAO_0000115 "Cells divide at an earlier stage of development compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001495" ; a owl:Class ; rdfs:label "cell division precocious" ; rdfs:subClassOf obo:WBPhenotype_0000439, obo:WBPhenotype_0000746, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000694 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051301 ] ) ] ] . obo:WBPhenotype_0001496 obo:IAO_0000115 "Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids (or homologous chromosomes) separate and migrate towards the poles of the spindle." ; oboInOwl:hasAlternativeId "WBPhenotype:0001214" ; oboInOwl:hasExactSynonym "metaphase to anaphase transition fails" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Mat" ; oboInOwl:id "WBPhenotype:0001496" ; a owl:Class ; rdfs:label "metaphase to anaphase transition defect" ; rdfs:subClassOf obo:WBPhenotype_0000740, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031577 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031577 ] ) ] ] . obo:WBPhenotype_0001497 obo:IAO_0000115 "Cells exhibit variations in the process whereby a cell progresses from metaphase to anaphase during mitosis, compared to control. Metaphase is the second stage of chromosome segregation in the cell cycle where chromosomes become aligned on the equatorial plate of the cell and anaphase is the stage where sister chromatids separate and migrate towards the poles of the spindle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001497" ; a owl:Class ; rdfs:label "mitotic metaphase to anaphase transition defect" ; rdfs:subClassOf obo:WBPhenotype_0001496, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007091 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CL_0000586 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007091 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CL_0000586 ] ) ] ] . obo:WBPhenotype_0001498 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the pseudopod of the sperm to carry out its normal functions or activities or be able to perceive and respond to stimuli, compared to control animals." ; oboInOwl:hasNarrowSynonym "sperm pseudopod physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001498" ; a owl:Class ; rdfs:label "sperm pseudopod physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000987, obo:WBPhenotype_0002551, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0031143 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:WBbt_0006798 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001912 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0031143 [ a owl:Restriction ; owl:onProperty obo:BFO_0000050 ; owl:someValuesFrom obo:WBbt_0006798 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001499 obo:IAO_0000115 "Variations in the process by which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle, compared to control." ; oboInOwl:hasNarrowSynonym "meiotic chromosome segregation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001499" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "meiotic chromosome segregation variant" ; rdfs:subClassOf obo:WBPhenotype_0000773, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045132 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045132 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001500 obo:IAO_0000115 "Any variation in the directed movement of a worm in response to a specific concentration gradient of pentanedione." ; oboInOwl:hasNarrowSynonym "pentanedione chemotaxis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001500" ; a owl:Class ; rdfs:label "pentanedione chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001467 . obo:WBPhenotype_0001501 obo:IAO_0000115 "Animals fail to discriminate between distinct odorants." ; oboInOwl:hasNarrowSynonym "odorant discrimination abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001501" ; a owl:Class ; rdfs:label "odorant discrimination defective" ; rdfs:subClassOf obo:WBPhenotype_0001048 . obo:WBPhenotype_0001502 obo:IAO_0000115 "Animals fail to respond to the concentration of a specific chemical that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001502" ; a owl:Class ; rdfs:label "chemical resistant" ; rdfs:subClassOf obo:WBPhenotype_0000523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_24431 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_24431 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001503 obo:IAO_0000115 "Any variation in the mechanisms used to ensure that axons in the ventral nerve cord maintain their correct positioning after termination of axonal outgrowth and target recognition compared to control." ; oboInOwl:hasNarrowSynonym "ventral nerve cord maintenance abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001503" ; a owl:Class ; rdfs:label "ventral nerve cord maintenance variant" ; rdfs:subClassOf obo:WBPhenotype_0000515 . obo:WBPhenotype_0001504 obo:IAO_0000115 "Sterility caused by aberrant maternal components required for normal postembryonic development and/or function of the germ line." ; oboInOwl:hasBroadSynonym "Mes" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001504" ; a owl:Class ; rdfs:label "maternal effect sterile" ; rdfs:subClassOf obo:WBPhenotype_0001037 . obo:WBPhenotype_0001505 obo:IAO_0000115 "Any variation in the processes that govern spontaneous backward locomotion compared to control." ; oboInOwl:hasNarrowSynonym "spontaneous reversal abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001505" ; a owl:Class ; rdfs:label "spontaneous reversal variant" ; rdfs:subClassOf obo:WBPhenotype_0002320 . obo:WBPhenotype_0001506 obo:IAO_0000115 "Any variation in the processes that govern the rate at which spontaneous backward locomotion is initiated compared to control." ; oboInOwl:hasNarrowSynonym "spontaneous reversal rate abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001506" ; a owl:Class ; rdfs:label "spontaneous reversal rate variant" ; rdfs:subClassOf obo:WBPhenotype_0001505 . obo:WBPhenotype_0001507 obo:IAO_0000115 "Animals fail to be affected by toxins produced by Bacillus thuringiensis (Bt toxins) in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001507" ; a owl:Class ; rdfs:label "Bacillus thuringiensis toxin resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011 . obo:WBPhenotype_0001508 obo:IAO_0000115 "Any perturbation that disrupts the fusion between the anchor cell and the surrounding utse syncytium. Such variations result in the loss of uterine-vulval connectivity and continuity." ; oboInOwl:hasNarrowSynonym "anchor cell fusion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001508" ; a owl:Class ; rdfs:label "anchor cell fusion defective" ; rdfs:subClassOf obo:WBPhenotype_0000165, obo:WBPhenotype_0000283 . obo:WBPhenotype_0001509 obo:IAO_0000115 "Any of the finger-like sensory sensilla that project from the tail and embed in the male fan are absent." ; oboInOwl:hasAlternativeId "WBPhenotype:0000407" ; oboInOwl:hasExactSynonym "ray loss" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001509" ; a owl:Class ; rdfs:label "rays missing" ; rdfs:subClassOf obo:WBPhenotype_0000199, obo:WBPhenotype_0000505, obo:WBPhenotype_0002174, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006941 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001510 obo:IAO_0000115 "Any variation in the processes that govern acquisition of neuronal cell fates compared to control." ; oboInOwl:hasNarrowSynonym "neuronal cell fate specification abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001510" ; a owl:Class ; rdfs:label "neuronal cell fate specification variant" ; rdfs:subClassOf obo:WBPhenotype_0000216, obo:WBPhenotype_0000816 . obo:WBPhenotype_0001511 obo:IAO_0000115 "Variations in the stereotypical migration pattern of the linker cell in a developing male compared to control." ; oboInOwl:hasNarrowSynonym "linker cell migration abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001511" ; a owl:Class ; rdfs:label "linker cell migration variant" ; rdfs:subClassOf obo:WBPhenotype_0000594 . obo:WBPhenotype_0001512 obo:IAO_0000115 "Bilaterally symmetric cell fail to acquire specific left-right asymmetric properties such as L/R specific cell position, cell death or gene expression." ; oboInOwl:hasBroadSynonym "Lsy" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001512" ; a owl:Class ; rdfs:label "loss of left right asymmetry" ; rdfs:subClassOf obo:WBPhenotype_0000216 . obo:WBPhenotype_0001513 obo:IAO_0000115 "Variations in the process of secretion of a class of membrane-bound vesicles found inside neurons, gland cells, and some epithelial cells in which the central core appears darkly stained when viewed in thin section by electron microscopy, compared to control. Exocytosis occurs via the fusion of the vesicle with the plasma membrane of a cell (Wormatlas)." ; oboInOwl:hasNarrowSynonym "dense core vesicle exocytosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001513" ; a owl:Class ; rdfs:label "dense core vesicle exocytosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000728 . obo:WBPhenotype_0001514 obo:IAO_0000115 "Variations in the uptake of a small membrane-bound organelle, filled with neurotransmitter(s) and/or neuropeptides, by the invagination of small region of the plasma membrane to form a new membrane-bounded vesicle compared to control(Wormatlas)." ; oboInOwl:hasNarrowSynonym "synaptic vesicle endocytosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001514" ; a owl:Class ; rdfs:label "synaptic vesicle endocytosis variant" ; rdfs:subClassOf obo:WBPhenotype_0001422, obo:WBPhenotype_0001684, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048488 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048488 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001515 obo:IAO_0000115 "Animals exhibit variations in the quantity or patterning of electron-dense columnar structures that join the basal and cortical cuticle layers, from that observed in control animals." ; oboInOwl:hasNarrowSynonym "struts abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001515" ; a owl:Class ; rdfs:label "struts variant" ; rdfs:subClassOf obo:WBPhenotype_0000948, obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060109 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060109 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001516 obo:IAO_0000115 "Animals exhibit a helically twisted cuticle. In practice the degree of twisting is measured as the number of helical twists the alae make about anterior/posterior axis of the animal." ; oboInOwl:hasNarrowSynonym "cuticle helicity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001516" ; a owl:Class ; rdfs:label "helical cuticle" ; rdfs:subClassOf obo:WBPhenotype_0000948, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000404 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000404 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001517 obo:IAO_0000115 "Animals exhibit variations in the circumferential pattern of ridges in the outer cortical layer of the cuticle, compared to that observed in control animals of the same developmental stage." ; oboInOwl:hasNarrowSynonym "annulae morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001517" ; a owl:Class ; rdfs:label "annulae morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000948, obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060107 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0060107 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001518 obo:IAO_0000115 "Any variation in the levels and/or localization of biogenic amines compared to control animals." ; oboInOwl:hasBroadSynonym "FIF" ; oboInOwl:hasNarrowSynonym "biogenic amine physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Formaldehyde induced fluorescence abnormal" ; oboInOwl:id "WBPhenotype:0001518" ; a owl:Class ; rdfs:label "biogenic amine physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000027 . obo:WBPhenotype_0001519 obo:IAO_0000115 "Any variation in the orderly movement of cells along the posterior axis of the animal (abolished, misdirected or incomplete) compared to control." ; oboInOwl:hasNarrowSynonym "abnormal posterior cell migration" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001519" ; a owl:Class ; rdfs:label "posterior cell migration variant" ; rdfs:subClassOf obo:WBPhenotype_0000594, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001633 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0016477 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001633 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0016477 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001520 obo:IAO_0000115 "Any variation in the orderly movement of neurons along the posterior axis of the animal(abolished, misdirected or incomplete) compared to control." ; oboInOwl:hasNarrowSynonym "abnormal posterior neuron migration" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001520" ; a owl:Class ; rdfs:label "posterior neuron migration variant" ; rdfs:subClassOf obo:WBPhenotype_0001140, obo:WBPhenotype_0001519, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001633 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0001764 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001633 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0001764 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001521 obo:IAO_0000115 "Embryos retract after the embryonic elongation process." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001521" ; a owl:Class ; rdfs:label "body elongation retracted" ; rdfs:subClassOf obo:WBPhenotype_0000749 . obo:WBPhenotype_0001522 obo:IAO_0000115 "The elongated sclerotized structures covered by a hardened layer of cuticle in the male tail (which are actively everted during copulation to fasten the male copulatory fan to the vulva) constitutively extend into the external environment through the cloacal opening. In C. elegans males there are two copulatory spicules." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001522" ; a owl:Class ; rdfs:label "spicules protrude" ; rdfs:subClassOf obo:WBPhenotype_0000908 . obo:WBPhenotype_0001523 obo:IAO_0000115 "Any variation in the makeup, density or area of the ECM compared to control." ; oboInOwl:hasNarrowSynonym "extracellular matrix abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001523" ; a owl:Class ; rdfs:label "extracellular matrix variant" ; rdfs:subClassOf obo:WBPhenotype_0000912, obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031012 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031012 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001524 obo:IAO_0000115 "Exhibition of quiescent behavior under inappropriate conditions and improper recovery from quiescent state. Quiescent behavior is normally coupled with lethargus." ; oboInOwl:hasNarrowSynonym "quiescence abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "narcoleptic" ; oboInOwl:id "WBPhenotype:0001524" ; a owl:Class ; rdfs:label "quiescence variant" ; rdfs:subClassOf obo:WBPhenotype_0000525 . obo:WBPhenotype_0001525 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of the posterior region of the pharynx compared to control." ; oboInOwl:hasNarrowSynonym "terminal bulb morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001525" ; a owl:Class ; rdfs:label "terminal bulb morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000709, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003732 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003732 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001526 obo:IAO_0000115 "Animals exhibit variations in the structure or organization of any one of the specialized sensory receptor cells of the nervous system that compared to control animals. In C. elegans, these specialized cells are characterized as having axoneme containing dendritic projections emanating from their cell body." ; oboInOwl:hasNarrowSynonym "ciliated neuron morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001526" ; a owl:Class ; rdfs:comment "WBbt:0006816." ; rdfs:label "ciliated neuron morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000299, obo:WBPhenotype_0000905, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006816 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006816 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001527 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head or along the tail, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "amphid phasmid sensillum morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001527" ; a owl:Class ; rdfs:comment "WBbt:0005391." ; rdfs:label "amphid phasmid sensillum morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000299 . obo:WBPhenotype_0001528 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of any component of the sensillum channel including the sheath and or socket cells, their junctions with each other, channel neurons or surrounding epithelia compared to control." ; oboInOwl:hasNarrowSynonym "sensillum accessory cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001528" ; a owl:Class ; rdfs:label "sensillum accessory cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000299 . obo:WBPhenotype_0001529 obo:IAO_0000115 "OBSOLETE: Any variation in the form, structure or composition of an interfacial epithelial cell which forms a specialized environment surrounding the ciliated sensory ending(s) of one or more neurons and is often accompanied by a more distal socket cell compared to control (Wormatlas)." ; obo:IAO_0100001 obo:WBPhenotype_0000972 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001529" ; a owl:Class ; rdfs:label "obsolete sensilium sheath cell variant" ; owl:deprecated true . obo:WBPhenotype_0001530 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake." ; oboInOwl:hasNarrowSynonym "cephalic sensillum morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001530" ; a owl:Class ; rdfs:comment "WBbt:0006920." ; rdfs:label "cephalic sensillum morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006920 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006920 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001531 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth." ; oboInOwl:hasNarrowSynonym "labial sensillum morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001531" ; a owl:Class ; rdfs:label "labial sensillum morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005107 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005107 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001532 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2." ; oboInOwl:hasNarrowSynonym "inner labial morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001532" ; a owl:Class ; rdfs:label "inner labial morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001531, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005116 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005116 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001533 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum." ; oboInOwl:hasNarrowSynonym "outer labial morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001533" ; a owl:Class ; rdfs:label "outer labial morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001531, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005501 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005501 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001534 obo:IAO_0000115 "Any variation in makeup, density or area of the ECM lending structure to neurons compared to control animals. In C. elegans, the neuronal ECM is sometimes referred to as a mantle." ; oboInOwl:hasNarrowSynonym "neuronal ECM abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001534" ; a owl:Class ; rdfs:label "neuronal ECM variant" ; rdfs:subClassOf obo:WBPhenotype_0001523 . obo:WBPhenotype_0001535 obo:IAO_0000115 "Animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC." ; oboInOwl:hasNarrowSynonym "deirid sensillum morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001535" ; a owl:Class ; rdfs:label "deirid sensillum morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000299, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006926 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006926 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001536 obo:IAO_0000115 "Embryos exhibit variations in the patterning of differentiated cell types, compared to control." ; oboInOwl:hasNarrowSynonym "embryonic cell patterning abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001536" ; a owl:Class ; rdfs:label "embryonic cell patterning variant" ; rdfs:subClassOf obo:WBPhenotype_0000050 . obo:WBPhenotype_0001537 obo:IAO_0000115 "Any variation in the ability of cells to monitor the quality of their mRNAs and degrade any transcripts that are poorly or incompletely translated compared to control." ; oboInOwl:hasNarrowSynonym "mRNA turnover abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001537" ; a owl:Class ; rdfs:label "mRNA surveillance variant" ; rdfs:subClassOf obo:WBPhenotype_0001283, obo:WBPhenotype_0001826, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0071028 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0071028 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001538 obo:IAO_0000115 "Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia." ; oboInOwl:hasNarrowSynonym "Smg" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001538" ; a owl:Class ; rdfs:label "mRNA surveillance defective" ; rdfs:subClassOf obo:WBPhenotype_0000028 . obo:WBPhenotype_0001539 obo:IAO_0000115 "Animals exhibit variations in the entry into the dauer stage when exposed to conditions that induce dauer formation in control animals." ; oboInOwl:hasNarrowSynonym "dauer induction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001539" ; a owl:Class ; rdfs:label "dauer induction variant" ; rdfs:subClassOf obo:WBPhenotype_0000308, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043053 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0043053 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001540 obo:IAO_0000115 "The life span of dauer-staged animals is either longer or shorter than that observed in control dauer animals." ; oboInOwl:hasNarrowSynonym "dauer lifespan abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001540" ; a owl:Class ; rdfs:label "dauer lifespan variant" ; rdfs:subClassOf obo:WBPhenotype_0000039, obo:WBPhenotype_0001547, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000050 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000050 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001541 obo:IAO_0000115 "Variations in the execution of the developmentally-regulated cell cycle arrest in the gonad during the dauer stage, compared to control." ; oboInOwl:hasNarrowSynonym "dauer gonad arrest abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001541" ; a owl:Class ; rdfs:label "dauer gonad arrest variant" ; rdfs:subClassOf obo:WBPhenotype_0000637 . obo:WBPhenotype_0001542 obo:IAO_0000115 "Any variation in the inhibition of feeding which is induced/occurs during the dauer stage compared to control." ; oboInOwl:hasNarrowSynonym "dauer feeding suppressed abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001542" ; a owl:Class ; rdfs:label "dauer feeding suppressed variant" ; rdfs:subClassOf obo:WBPhenotype_0001001 . obo:WBPhenotype_0001543 obo:IAO_0000115 "Dauer stage animals exhibit a decrease in self-propelled movement on a solid medium compared to control animals." ; oboInOwl:hasNarrowSynonym "dauer reduced locomotion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001543" ; a owl:Class ; rdfs:label "dauer reduced locomotion variant" ; rdfs:subClassOf obo:WBPhenotype_0001001 . obo:WBPhenotype_0001544 obo:IAO_0000115 "Variations in the state or activity of a dauer stage organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus, compared to control." ; oboInOwl:hasNarrowSynonym "dauer sensory response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001544" ; a owl:Class ; rdfs:label "dauer sensory response variant" ; rdfs:subClassOf obo:WBPhenotype_0001001 . obo:WBPhenotype_0001545 obo:IAO_0000115 "Any variation in the overall structure or appearance of an animal progressing through an alternative larval stage in response to environmental stresses compared to control animals." ; oboInOwl:hasNarrowSynonym "dauer body morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001545" ; a owl:Class ; rdfs:label "dauer body morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000934, obo:WBPhenotype_0002555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0007833 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001546 obo:IAO_0000115 "Variations which lead to the decreased ability of dauer larva to survive at extreme conditions, such as high or low temperatures, the presence of dilute acids, detergents, anesthetics, or even fixatives, compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "dauer resistance to harsh conditions abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001546" ; a owl:Class ; rdfs:label "dauer resistance to harsh conditions variant" ; rdfs:subClassOf obo:WBPhenotype_0002527 . obo:WBPhenotype_0001547 obo:IAO_0000115 "Animals exhibit variations in the chemical reactions and pathways that occur during the dauer life stage, compared to control." ; oboInOwl:hasExactSynonym "dauer metabolism abnormal", "dauer metabolism variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001547" ; a owl:Class ; rdfs:label "dauer metabolism phenotype" ; rdfs:subClassOf obo:WBPhenotype_0002527 . obo:WBPhenotype_0001548 obo:IAO_0000115 "Any variation in the ratio of the body length to body width in a dauer stage animal, compared to control. Long thin animals will have a high axial ratio." ; oboInOwl:hasNarrowSynonym "dauer axial ratio abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001548" ; a owl:Class ; rdfs:label "dauer axial ratio variant" ; rdfs:subClassOf obo:WBPhenotype_0001545 . obo:WBPhenotype_0001549 obo:IAO_0000115 "Dauer stage animals exhibit variations in the form, structure or composition of the chain of cuboidal cells which form a central lumen lined by microvilli that allow the passage of food, compared to control. Food passes from the posterior pharynx to the intestine where it is digested and then on to the rectum which processes the waste products for excretion." ; oboInOwl:hasNarrowSynonym "dauer gut abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001549" ; a owl:Class ; rdfs:label "dauer gut variant" ; rdfs:subClassOf obo:WBPhenotype_0001545 . obo:WBPhenotype_0001550 obo:IAO_0000115 "Variations in the form or composition of the cuticle-lined lumenal region which lies just behind the lips at the entrance to the pharyngeal lumen in dauer stage animals compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "dauer buccal cavity morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001550" ; a owl:Class ; rdfs:label "dauer buccal cavity morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001545, obo:WBPhenotype_0002558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005255 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005255 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001551 obo:IAO_0000115 "Any variation in the progression of the formation of the rigid external coating (which is secreted by the hypodermis, seam and some interfacial epithelial cells) during the dauer larva stage, compared to control animals (Wormatlas). The dauer larval stage is a developmentally arrested larval stage that is specialized for survival under harsh, or otherwise unfavorable environmental conditions." ; oboInOwl:hasNarrowSynonym "dauer cuticle abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001551" ; a owl:Class ; rdfs:label "dauer cuticle variant" ; rdfs:subClassOf obo:WBPhenotype_0000948, obo:WBPhenotype_0001545, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005755 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001552 obo:IAO_0000115 "Variations in the form or composition of the mouthparts at the anterior end of the digestive tract during the dauer stage, compared to control." ; oboInOwl:hasNarrowSynonym "dauer pharynx morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001552" ; a owl:Class ; rdfs:label "dauer pharynx morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000709, obo:WBPhenotype_0001545, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001553 obo:IAO_0000115 "Dauer stage animals exhibit variations in the form, structure or composition of a pair of large cells in the head that fuse to form a single gland whose contents are released into the excretory duct through a specialized secretory membrane, compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "dauer excretory gland abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001553" ; a owl:Class ; rdfs:label "dauer excretory gland variant" ; rdfs:subClassOf obo:WBPhenotype_0000914, obo:WBPhenotype_0001545, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005776 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005776 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001554 obo:IAO_0000115 "Dauer stage animals exhibit variations in the form, structure or composition of any portion of the extreme anterior part of their body compared to control." ; oboInOwl:hasNarrowSynonym "dauer nose morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001554" ; a owl:Class ; rdfs:label "dauer nose morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001545 . obo:WBPhenotype_0001555 obo:IAO_0000115 "Any variations in the form, structure or composition of a set of interacting or interdependent entities forming the dauer sensory system, compared to control. The dauer sensory system is used to perceive the physical and chemical environment during the dauer larval stage." ; oboInOwl:hasNarrowSynonym "dauer sensory system morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001555" ; a owl:Class ; rdfs:label "dauer sensory system morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001545 . obo:WBPhenotype_0001556 obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sense organs comprised of ciliated sensory nerve endings enveloped by sheath and/or socket cells, from that observed in control animals." ; oboInOwl:hasNarrowSynonym "dauer sensillum abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001556" ; a owl:Class ; rdfs:label "dauer sensillum variant" ; rdfs:subClassOf obo:WBPhenotype_0000299, obo:WBPhenotype_0001555, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006929 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001557 obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the sensilla of the mouth compared to control. In C. elegans, these sensillum are arranged in two (inner and outer) concentric rings around the mouth." ; oboInOwl:hasNarrowSynonym "dauer labial sensillum abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001557" ; a owl:Class ; rdfs:label "dauer labial sensillum variant" ; rdfs:subClassOf obo:WBPhenotype_0001531, obo:WBPhenotype_0001556, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005107 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005107 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001558 obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of any component of any specialized chemosensory organs located on the head, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "dauer amphid sensillum abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001558" ; a owl:Class ; rdfs:label "dauer amphid sensillum variant" ; rdfs:subClassOf obo:WBPhenotype_0000256, obo:WBPhenotype_0001556, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005391 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005391 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001559 obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the sensilla situated laterally in the anterior (ADE) or the posterior (PDE) of the animal compared to control. In C. elegans, each of the 4 deirid sensilla (2ADE, 2 PDE) contains a pair of neurons with ciliated dendritic processes that lie in a channel formed by a socket cell and invaginated sheath cell. The cilia of the deirids terminate in the subcuticle and are not exposed to the outside; however occasionally take up FITC." ; oboInOwl:hasNarrowSynonym "dauer deirid sensillum abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001559" ; a owl:Class ; rdfs:label "dauer deirid sensillum variant" ; rdfs:subClassOf obo:WBPhenotype_0001535, obo:WBPhenotype_0001556, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006926 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006926 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001560 obo:IAO_0000115 "OBSOLETE." ; oboInOwl:consider obo:WBPhenotype_0001550 ; oboInOwl:hasNarrowSynonym "dauer sensory system plug abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001560" ; a owl:Class ; rdfs:label "obsolete dauer sensory system plug variant" ; owl:deprecated true . obo:WBPhenotype_0001561 obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the inner labial ring compared to control. In C. elegans, the ring is composed of six sensilla, which include associated neurons IL1 & IL2." ; oboInOwl:hasNarrowSynonym "dauer inner labial sensillum abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001561" ; a owl:Class ; rdfs:label "dauer inner labial sensillum variant" ; rdfs:subClassOf obo:WBPhenotype_0001532, obo:WBPhenotype_0001557, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005116 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005116 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001562 obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of the components of the outer labial ring compared to control. In C. elegans, this ring consists of four sensilla (OLQ) or the two additional lateral sensilla (OLL), which are part of the labial sensillum." ; oboInOwl:hasNarrowSynonym "dauer outer labial sensillum abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001562" ; a owl:Class ; rdfs:label "dauer outer labial sensillum variant" ; rdfs:subClassOf obo:WBPhenotype_0001533, obo:WBPhenotype_0001557, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005501 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005501 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001563 obo:IAO_0000115 "Dauer stage animals exhibit variations in the quantity, structure or organization of any component of a specialized sensory organ in the head that contains a CEP receptor neuron, compared to control. In C. elegans, cells in these organs are refractory to FITC dye uptake." ; oboInOwl:hasNarrowSynonym "dauer cephalic sensillum abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001563" ; a owl:Class ; rdfs:label "dauer cephalic sensillum variant" ; rdfs:subClassOf obo:WBPhenotype_0001530, obo:WBPhenotype_0001556, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006920 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006920 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:WBls_0000032 ] ) ] ] . obo:WBPhenotype_0001564 obo:IAO_0000115 "The window of production of self-fertilized eggs exceeds or does not extend to the same length as control." ; oboInOwl:hasNarrowSynonym "duration of self fertility abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001564" ; a owl:Class ; rdfs:label "duration of self fertility variant" ; rdfs:subClassOf obo:WBPhenotype_0000806 . obo:WBPhenotype_0001565 obo:IAO_0000115 "Failure to execute characteristic response to lysine as defined by control animals. In C. elegans, lysine is an attractant." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001565" ; a owl:Class ; rdfs:label "lysine chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001441, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_25094 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050918 ] [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:CHEBI_25094 ] ) ] ] . obo:WBPhenotype_0001566 obo:IAO_0000115 "Any variation in the process that regulates the migration of ventral epidermal cells toward the ventral midline (to encase underlying cells in an epithelial monolayer) in developing embryos compared to control." ; oboInOwl:hasNarrowSynonym "ventral enclosure abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001566" ; a owl:Class ; rdfs:label "ventral enclosure variant" ; rdfs:subClassOf obo:WBPhenotype_0000749 . obo:WBPhenotype_0001567 obo:IAO_0000115 "Nuclei of specific cells are larger compared to control animals." ; oboInOwl:hasExactSynonym "nuclear size increased" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001567" ; a owl:Class ; rdfs:label "nuclei enlarged" ; rdfs:subClassOf obo:WBPhenotype_0002607, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000586 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001568 obo:IAO_0000115 "Any variation in the export of mRNA from the cell nucleus compared to control." ; oboInOwl:hasNarrowSynonym "mRNA export abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001568" ; a owl:Class ; rdfs:label "mRNA export variant" ; rdfs:subClassOf obo:WBPhenotype_0000114, obo:WBPhenotype_0001706, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006406 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006406 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001569 obo:IAO_0000115 "The characteristic organization of myosin filaments into discrete A-bands within the muscle cells is disrupted. In C. elegans, myosin filaments no longer appear as continuous longitudinally oriented fibers across the muscle quadrants." ; oboInOwl:hasNarrowSynonym "body wall muscle myosin organization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Dim", "body wall muscle thick myofilament organization abnormal" ; oboInOwl:id "WBPhenotype:0001569" ; a owl:Class ; rdfs:label "body wall muscle myosin organization defective" ; rdfs:subClassOf obo:WBPhenotype_0000782 . obo:WBPhenotype_0001570 obo:IAO_0000115 "The characteristic organization of actin filaments into I-bands is disrupted. In C. elegans, actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants." ; oboInOwl:hasNarrowSynonym "body wall muscle actin organization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "body wall muscle thin myofilament organization abnormal" ; oboInOwl:id "WBPhenotype:0001570" ; a owl:Class ; rdfs:label "body wall muscle actin organization defective" ; rdfs:subClassOf obo:WBPhenotype_0000781 . obo:WBPhenotype_0001571 obo:IAO_0000115 "Variations in the accumulation of muscle proteins at membranes where adjacent muscle cells contact each other and the hypodermis compared to control. In C. elegans, during early embryonic body wall muscle development, muscle, basement membrane, and hypodermal components are all colocalized in a continuous linear structure at the site of muscle-hypodermal contact." ; oboInOwl:hasNarrowSynonym "body wall muscle cell polarization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001571" ; a owl:Class ; rdfs:label "body wall muscle cell polarization variant" ; rdfs:subClassOf obo:WBPhenotype_0000926 . obo:WBPhenotype_0001572 obo:IAO_0000115 "Animals that are not ordinarily male, exhibit male-specific attributes. In C. elegans, XX animals exhibit male-specific attributes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001572" ; a owl:Class ; rdfs:label "masculinized" ; rdfs:subClassOf obo:WBPhenotype_0001022 . obo:WBPhenotype_0001573 obo:IAO_0000115 "Animals exhibit variations in the response to the addition of nicotine compared to that observed in control animals. Nicotine is a cholinergic agonist." ; oboInOwl:hasNarrowSynonym "nicotine response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001573" ; a owl:Class ; rdfs:label "nicotine response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0001574 obo:IAO_0000115 "Animals exhibit variations in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." ; oboInOwl:hasNarrowSynonym "ATP levels abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001574" ; a owl:Class ; rdfs:label "ATP levels variant" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_15422 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_15422 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001575 obo:IAO_0000115 "Animals exhibit a decrease in the cellular levels of Adenosine-5'-triphosphate (ATP), compared to control. ATP is a nucleotide that plays a versatile role in cell biology." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001575" ; a owl:Class ; rdfs:label "ATP levels reduced" ; rdfs:subClassOf obo:WBPhenotype_0001574, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_15422 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_15422 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001576 obo:IAO_0000115 "Variations in the spatial distribution of the mitochondria within the cell compared to control." ; oboInOwl:hasNarrowSynonym "mitochondria spacing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001576" ; a owl:Class ; rdfs:label "mitochondria spacing variant" ; rdfs:subClassOf obo:WBPhenotype_0001401, obo:WBPhenotype_0002098, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000140 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001577 obo:IAO_0000115 "Animals exhibit variations in the parallel arrangement of mitochondria within a cell compared to control." ; oboInOwl:hasNarrowSynonym "mitochondria alignment abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001577" ; a owl:Class ; rdfs:label "mitochondria alignment variant" ; rdfs:subClassOf obo:WBPhenotype_0001576, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001652 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001652 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005739 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001578 obo:IAO_0000115 "Animals fail to respond to the concentration of cholinergic agonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001578" ; a owl:Class ; rdfs:label "cholinergic agonist resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38324 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38324 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001579 obo:IAO_0000115 "Animals respond to a cholinergic agonist at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001579" ; a owl:Class ; rdfs:label "cholinergic agonist hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38324 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_38324 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001580 obo:IAO_0000115 "Any variation in the progression of the controlled breakdown of the nuclear envelope, compared to control." ; oboInOwl:hasNarrowSynonym "nuclear envelope breakdown abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001580" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "nuclear envelope breakdown variant" ; rdfs:subClassOf obo:WBPhenotype_0000519, obo:WBPhenotype_0002037, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051081 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051081 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001581 obo:IAO_0000115 "Levels of transcripts associated with genes on the X chromosome are increased compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001581" ; a owl:Class ; rdfs:label "X linked gene expression enhanced" ; rdfs:subClassOf obo:WBPhenotype_0000718 . obo:WBPhenotype_0001582 obo:IAO_0000115 "Levels of transcripts associated with genes on the X chromosome are decreased compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001582" ; a owl:Class ; rdfs:label "X linked gene expression reduced" ; rdfs:subClassOf obo:WBPhenotype_0000718 . obo:WBPhenotype_0001583 obo:IAO_0000115 "Animals segregate progeny with 3 X chromosomes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001583" ; a owl:Class ; rdfs:label "XXX progeny" ; rdfs:subClassOf obo:WBPhenotype_0001664 . obo:WBPhenotype_0001584 obo:IAO_0000115 "Any variation in the movement of chromosomes to the spindle equator during mitosis compared to control animals." ; oboInOwl:hasNarrowSynonym "chromosome alignment at metaphase plate abnormal", "chromosome alignment at metaphase plate variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "chromosome congression" ; oboInOwl:id "WBPhenotype:0001584" ; a owl:Class ; rdfs:label "chromosome alignment variant" ; rdfs:subClassOf obo:WBPhenotype_0000773, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051310 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051310 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001585 obo:IAO_0000115 "Any variation in a cell's ability to divide asymmetrically to produce two daughter cells with different developmental potentials compared to control." ; oboInOwl:hasNarrowSynonym "asymmetric cell division abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001585" ; a owl:Class ; rdfs:label "asymmetric cell division variant" ; rdfs:subClassOf obo:WBPhenotype_0001235, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008356 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008356 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001586 obo:IAO_0000115 "Animals contain more than one anchor cell. In C. elegans, presumptive ventral uterine cells undergo fate transformation and instead acquire the properties of an anchor cell (often due to defects in lateral signaling)." ; oboInOwl:hasNarrowSynonym "double anchor cell" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001586" ; a owl:Class ; rdfs:label "multiple anchor cells" ; rdfs:subClassOf obo:WBPhenotype_0002175, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004522 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004522 ] ) ] ] . obo:WBPhenotype_0001587 obo:IAO_0000115 "Animals exhibit variations in the formation and/or arrangement of actin, an abundant cytoskeletal protein in most cells, often linked to the plasma membrane and concentrated at cell junctions compared to control (Wormatlas)." ; oboInOwl:hasExactSynonym "actin organization biogenesis variant" ; oboInOwl:hasNarrowSynonym "actin organization biogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001587" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "actin organization biogenesis phenotype" ; rdfs:subClassOf obo:WBPhenotype_0001345, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030036 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030036 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001588 obo:IAO_0000115 "Animals exhibit variations in the form, structure, composition or arrangement of a robust macromolecular array, composed primarily of tubulin, which forms long extended cytoskeletal elements compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "microtubule organization biogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001588" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "microtubule organization biogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001345, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000226 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000226 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001589 obo:IAO_0000115 "Any variation that alters the characteristic de novo formation of a microtubule compared to control." ; oboInOwl:hasNarrowSynonym "microtubule nucleation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001589" ; a owl:Class ; rdfs:label "microtubule nucleation variant" ; rdfs:subClassOf obo:WBPhenotype_0001588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007020 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001590 obo:IAO_0000115 "Any variation that alters the characteristic removal of tubulin heterodimers from one or both ends of a microtubule compared to control." ; oboInOwl:hasNarrowSynonym "microtubule depolymerization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001590" ; a owl:Class ; rdfs:label "microtubule depolymerization variant" ; rdfs:subClassOf obo:WBPhenotype_0001588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007019 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007019 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001591 obo:IAO_0000115 "Any variation that alters the characteristic addition of tubulin heterodimers to one or both ends of a microtubule compared to control." ; oboInOwl:hasNarrowSynonym "microtubule polymerization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001591" ; a owl:Class ; rdfs:label "microtubule polymerization variant" ; rdfs:subClassOf obo:WBPhenotype_0001369, obo:WBPhenotype_0001588, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0046785 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0046785 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001592 obo:IAO_0000115 "Alternating periods of stopping and moving; Motion is interrupted by periods of inactivity lasting several seconds." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001592" ; a owl:Class ; rdfs:label "fainter" ; rdfs:subClassOf obo:WBPhenotype_0002308 . obo:WBPhenotype_0001593 obo:IAO_0000115 "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, compared to control. In C. elegans this silencing occurs only in the germline." ; oboInOwl:hasNarrowSynonym "transgene silencing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001593" ; a owl:Class ; rdfs:label "transgene silencing variant" ; rdfs:subClassOf obo:WBPhenotype_0002063 . obo:WBPhenotype_0001594 obo:IAO_0000115 "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the germline, compared to control." ; oboInOwl:hasNarrowSynonym "germline transgene silencing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001594" ; a owl:Class ; rdfs:label "germline transgene silencing variant" ; rdfs:subClassOf obo:WBPhenotype_0001593 . obo:WBPhenotype_0001595 obo:IAO_0000115 "Animals exhibit variations in the homology-dependent transcriptional level silencing of the expression of exogenous DNA that has been introduced into the organism, in the soma, compared to control." ; oboInOwl:hasNarrowSynonym "somatic transgene silencing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001595" ; a owl:Class ; rdfs:label "somatic transgene silencing variant" ; rdfs:subClassOf obo:WBPhenotype_0001593 . obo:WBPhenotype_0001596 obo:IAO_0000115 "Swelling of the tail hypodermis resulting in a prematurely-truncated and thickened appearance of the tail. In C. elegans, this is usually applies to hermaphrodites." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001596" ; a owl:Class ; rdfs:label "tail bobbed" ; rdfs:subClassOf obo:WBPhenotype_0000073 . obo:WBPhenotype_0001597 obo:IAO_0000115 "Any variation that results in a fewer than control number of muscle cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001597" ; a owl:Class ; rdfs:label "muscle missing" ; rdfs:subClassOf obo:WBPhenotype_0000622, obo:WBPhenotype_0002174, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001997 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003675 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001598 obo:IAO_0000115 "Treatment with inhibitors of serotonin reuptake does not elicit the same response as observed for control animals." ; oboInOwl:hasNarrowSynonym "inhibitor of serotonin uptake abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001598" ; a owl:Class ; rdfs:label "inhibitor of serotonin uptake variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0001599 obo:IAO_0000115 "Animals fail to respond to the concentration of ouabain that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, resistance to ouabain is often assayed via body contraction response." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001599" ; a owl:Class ; rdfs:label "ouabain resistant" ; rdfs:subClassOf obo:WBPhenotype_0000331, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_472805 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_472805 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001600 obo:IAO_0000115 "Animals require increased concentration or longer exposure to ouabain to elicit the rapid muscular contractions seen in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001600" ; a owl:Class ; rdfs:label "contraction response to ouabain resistant" ; rdfs:subClassOf obo:WBPhenotype_0001599 . obo:WBPhenotype_0001601 obo:IAO_0000115 "Animals fail to respond to the concentration of biogenic amine receptor antagonist that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasNarrowSynonym "serotonin receptor antagonist" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001601" ; a owl:Class ; rdfs:label "biogenic amine receptor antagonist resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011 . obo:WBPhenotype_0001602 obo:IAO_0000115 "Animals fail to respond to the concentration of methiothepin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001602" ; a owl:Class ; rdfs:label "methiothepin resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001601, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_64203 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_64203 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001603 obo:IAO_0000115 "Animals fail to respond to the concentration of cyproheptadine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001603" ; a owl:Class ; rdfs:label "cyproheptadine resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001601, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4046 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4046 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001604 obo:IAO_0000115 "Animals fail to respond to the concentration of mianserin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "dibenzazepine resistant" ; oboInOwl:id "WBPhenotype:0001604" ; a owl:Class ; rdfs:label "mianserin resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001601, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_51137 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_51137 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001605 obo:IAO_0000115 "Animals do not live longer in response to mianserin compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001605" ; a owl:Class ; rdfs:label "extended life span response to mianserin resistant" ; rdfs:subClassOf obo:WBPhenotype_0001604 . obo:WBPhenotype_0001606 obo:IAO_0000115 "Animals respond to ethanol at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasBroadSynonym "alcohol sensitive" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001606" ; a owl:Class ; rdfs:label "ethanol hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000008, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_16236 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_16236 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001607 obo:IAO_0000115 "Animals become paralyzed in response to ethanol at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001607" ; a owl:Class ; rdfs:label "paralysis response to ethanol hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001606 . obo:WBPhenotype_0001608 obo:IAO_0000115 "Animals respond to the anesthetic enflurane at lower concentrations or shorter exposure times than control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ether hypersensitive" ; oboInOwl:id "WBPhenotype:0001608" ; a owl:Class ; rdfs:label "enflurane hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000008, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4792 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4792 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001609 obo:IAO_0000115 "Animals respond to the anesthetic isoflurane at lower concentrations or shorter response times than control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ether hypersensitive" ; oboInOwl:id "WBPhenotype:0001609" ; a owl:Class ; rdfs:label "isoflurane hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000008, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6015 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6015 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001610 obo:IAO_0000115 "Animals respond to the anesthetic ether at lower concentrations or shorter response times than control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ether hypersensitive" ; oboInOwl:id "WBPhenotype:0001610" ; a owl:Class ; rdfs:label "diethyl ether hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000008, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_35702 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_35702 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001611 obo:IAO_0000115 "Animals respond to the lipid-soluble anesthetic halothane at lower concentrations or shorter response times compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001611" ; a owl:Class ; rdfs:label "halothane hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000008, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_5615 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_5615 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001612 obo:IAO_0000115 "Animals fail to respond to the concentration of ethanol that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to ethanol to elicit the response compared to control animals. In C.elegans the phenotype designation Jud is short for JUDang, which is Korean for resistant to alcohol." ; oboInOwl:hasBroadSynonym "Jud", "alcohol resistant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001612" ; a owl:Class ; rdfs:label "ethanol resistant" ; rdfs:subClassOf obo:WBPhenotype_0000009, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_16236 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_16236 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001613 obo:IAO_0000115 "Animals in the presence of ethanol continue to respond to touch under conditions when control worms have stopped responding to stimuli." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001613" ; a owl:Class ; rdfs:label "paralysis response to ethanol resistant" ; rdfs:subClassOf obo:WBPhenotype_0001612 . obo:WBPhenotype_0001614 obo:IAO_0000115 "Animals exhibit variations in their response to a specific anticonvulsant compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "anticonvulsant response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001614" ; a owl:Class ; rdfs:label "anticonvulsant response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0001615 obo:IAO_0000115 "Animals fail to respond to the concentration of compounds that act as anticonvulsants that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001615" ; a owl:Class ; rdfs:label "anticonvulsant resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001614, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_35623 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_35623 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001616 obo:IAO_0000115 "Animals fail to respond to the concentration of trimethadione, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001616" ; a owl:Class ; rdfs:label "trimethadione resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001615, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_9727 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_9727 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001617 obo:IAO_0000115 "Animals fail to respond to the concentration of ethosuximide, which acts as an anticonvulsant, that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001617" ; a owl:Class ; rdfs:label "ethosuximide resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001615, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4887 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_4887 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001618 obo:IAO_0000115 "Animals fail to respond to the concentration of the anesthetic halothane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001618" ; a owl:Class ; rdfs:label "halothane resistant" ; rdfs:subClassOf obo:WBPhenotype_0000009, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_5615 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_5615 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001619 obo:IAO_0000115 "Animals fail to respond to the concentration of the volatile anesthetic isoflurane that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001619" ; a owl:Class ; rdfs:label "isoflurane resistant" ; rdfs:subClassOf obo:WBPhenotype_0000009, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6015 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6015 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001620 obo:IAO_0000115 "Animals exhibit variations in their response to oxidative stress compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "organism oxidative stress response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001620" ; a owl:Class ; rdfs:label "organism oxidative stress response variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006979 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006979 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001621 obo:IAO_0000115 "Animals respond to a lower concentration of reactive oxygen species or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001621" ; a owl:Class ; rdfs:label "organism oxidative stress response hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001620 . obo:WBPhenotype_0001622 obo:IAO_0000115 "Animals lay eggs at a greater rate in response to exogenous serotonin compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001622" ; a owl:Class ; rdfs:label "egg laying serotonin hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000023, obo:WBPhenotype_0001629, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001551 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001551 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] ) ] ] . obo:WBPhenotype_0001623 obo:IAO_0000115 "Any variation in the posture of the male tail after application of exogenous serotonin compared to control. In C. elegans, males respond with a tight ventral curling of the male tail in response to serotonin." ; oboInOwl:hasNarrowSynonym "male tail curling serotonin abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001623" ; a owl:Class ; rdfs:label "male tail curling serotonin variant" ; rdfs:subClassOf obo:WBPhenotype_0001232 . obo:WBPhenotype_0001624 obo:IAO_0000115 "Animals fail to respond to the concentration of serotonin that elicits a male tail curling response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001624" ; a owl:Class ; rdfs:label "male tail curling serotonin resistant" ; rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001623 . obo:WBPhenotype_0001625 obo:IAO_0000115 "Males respond to serotonin by curling their tails at a lower concentration or a shorter exposure compared to control animals. In C. elegans males respond to serotonin with a tight ventral curling of the male tail and posterior body." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001625" ; a owl:Class ; rdfs:label "male tail curling serotonin hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000023, obo:WBPhenotype_0001623 . obo:WBPhenotype_0001626 obo:IAO_0000115 "Any variation in the locomotion rate after application of exogenous serotonin compared to control." ; oboInOwl:hasNarrowSynonym "locomotion rate serotonin abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001626" ; a owl:Class ; rdfs:label "locomotion rate serotonin variant" ; rdfs:subClassOf obo:WBPhenotype_0001232 . obo:WBPhenotype_0001627 obo:IAO_0000115 "The decrease in locomotion rate in the presence of serotonin is greater than control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "locomotion rate serotonin reduced" ; oboInOwl:id "WBPhenotype:0001627" ; a owl:Class ; rdfs:label "locomotion rate serotonin hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000023, obo:WBPhenotype_0001626 . obo:WBPhenotype_0001628 obo:IAO_0000115 "Animals fail to decrease their locomotion rate in response the concentration of serotonin that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "locomotion rate serotonin increased" ; oboInOwl:id "WBPhenotype:0001628" ; a owl:Class ; rdfs:label "locomotion rate serotonin resistant" ; rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001626, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001551 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007626 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001551 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007626 ] ) ] ] . obo:WBPhenotype_0001629 obo:IAO_0000115 "Any variation in egg laying behavior after application of exogenous serotonin compared to control. In C. elegans, serotonin induces egg laying." ; oboInOwl:hasNarrowSynonym "egg laying serotonin abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001629" ; a owl:Class ; rdfs:label "egg laying serotonin variant" ; rdfs:subClassOf obo:WBPhenotype_0001101, obo:WBPhenotype_0001232, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001457 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001457 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_28790 ] [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0018991 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001630 obo:IAO_0000115 "Any variation in the developmental progression of the intestine that leads to a blockage in the alimentary canal." ; oboInOwl:hasBroadSynonym "Gob" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001630" ; a owl:Class ; rdfs:label "gut obstructed" ; rdfs:subClassOf obo:WBPhenotype_0000708, obo:WBPhenotype_0000710, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001819 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001819 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001631 obo:IAO_0000115 "Animals produce ova/sperm that contain no X chromosome in a nonmendelian segregation pattern." ; oboInOwl:hasNarrowSynonym "nullo X gamete abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001631" ; a owl:Class ; rdfs:label "nullo X gamete" ; rdfs:subClassOf obo:WBPhenotype_0001664 . obo:WBPhenotype_0001632 obo:IAO_0000115 "Animals produce ova/sperm that contain 2 X chromosomes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001632" ; a owl:Class ; rdfs:label "diplo X gamete" ; rdfs:subClassOf obo:WBPhenotype_0001664 . obo:WBPhenotype_0001633 obo:IAO_0000115 "Animals produce ova/sperm that contain lethal factors as a result of chromosomal disjunction defects." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001633" ; a owl:Class ; rdfs:label "lethal gamete" ; rdfs:subClassOf obo:WBPhenotype_0001174, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CL_0000300 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000718 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CL_0000300 ] ) ] ] . obo:WBPhenotype_0001634 obo:IAO_0000115 "Animals respond to compounds that elicit electrophilic stress at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001634" ; a owl:Class ; rdfs:label "organism electrophilic stress hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000067 . obo:WBPhenotype_0001635 obo:IAO_0000115 "Animals contain an excess number of pharyngeal cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001635" ; a owl:Class ; rdfs:label "excess pharyngeal cells" ; rdfs:subClassOf obo:WBPhenotype_0000707, obo:WBPhenotype_0002175, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005460 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005460 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001636 obo:IAO_0000115 "Animals contain an excess number of intestinal cells compared to control. In C. elegans, intestinal cells are derived from E-blastomere. The overproduction of intestinal tissues is a result of other blastomeres adopting an E-like fate or excess cell proliferation in the E lineage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001636" ; a owl:Class ; rdfs:label "excess intestinal cells" ; rdfs:subClassOf obo:WBPhenotype_0000708, obo:WBPhenotype_0002175, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005792 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000470 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005792 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001637 obo:IAO_0000115 "Embryos fail to generate cells that exhibit intestinal specification. In C. elegans, the E blastomere is the precursor of all the intestinal cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001637" ; a owl:Class ; rdfs:label "no Intestine" ; rdfs:subClassOf obo:WBPhenotype_0000708, obo:WBPhenotype_0002174, obo:WBPhenotype_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005772 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001638 obo:IAO_0000115 "OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes." ; obo:IAO_0100001 obo:WBPhenotype_0002561 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001638" ; a owl:Class ; rdfs:label "obsolete endosome fusion defective" ; owl:deprecated true . obo:WBPhenotype_0001639 obo:IAO_0000115 "Animals exhibit a decrease in their high-speed movement in the forward direction with brief backward movement compared to control. In C. elegans, Animals do not move more than a few body lengths from their starting position and searches occur locally with pivoting behavior." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lurcher", "path range decreased" ; oboInOwl:id "WBPhenotype:0001639" ; a owl:Class ; rdfs:label "roaming reduced" ; rdfs:subClassOf obo:WBPhenotype_0000238, obo:WBPhenotype_0001213, obo:WBPhenotype_0002315 . obo:WBPhenotype_0001640 obo:IAO_0000115 "Animals are unable to acidify compartments to the same level as that observed in control animals given the same stimulus." ; oboInOwl:hasNarrowSynonym "acidification level abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001640" ; a owl:Class ; rdfs:label "acidification level defective" ; rdfs:subClassOf obo:WBPhenotype_0000607 . obo:WBPhenotype_0001641 obo:IAO_0000115 "Animals lack or exhibit defects in the posterior body muscle contractions during the defecation cycle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "pBoc" ; oboInOwl:id "WBPhenotype:0001641" ; a owl:Class ; rdfs:label "posterior body wall contraction defective" ; rdfs:subClassOf obo:WBPhenotype_0000157 . obo:WBPhenotype_0001642 obo:IAO_0000115 "Variations that disrupt stereotypical embryonic cleavage patterns (such as cleavage rate, division axes or asymmetric division)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001642" ; a owl:Class ; rdfs:label "cell cleavage variant emb" ; rdfs:subClassOf obo:WBPhenotype_0000266 . obo:WBPhenotype_0001643 obo:IAO_0000115 "Embryos generate an excess number of hypodermal cells compared to control." ; oboInOwl:hasBroadSynonym "Skn" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001643" ; a owl:Class ; rdfs:label "excess hypodermal cells" ; rdfs:subClassOf obo:WBPhenotype_0002175, obo:WBPhenotype_0002569 . obo:WBPhenotype_0001644 obo:IAO_0000115 "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of proteins in the organism compared to control." ; oboInOwl:hasNarrowSynonym "protein metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001644" ; a owl:Class ; rdfs:label "protein metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000463, obo:WBPhenotype_0000585, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0019538 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0019538 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001645 obo:IAO_0000115 "Variations in the chemical reactions and pathways resulting in the directed breakdown of a protein (via the destruction of its native, active configuration) compared to control." ; oboInOwl:hasNarrowSynonym "protein degradation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001645" ; a owl:Class ; rdfs:label "protein degradation variant" ; rdfs:subClassOf obo:WBPhenotype_0001644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030163 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030163 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001646 obo:IAO_0000115 "Embryos fail to generate cells that exhibit pharyngeal specification." ; oboInOwl:hasBroadSynonym "Pha" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001646" ; a owl:Class ; rdfs:label "no pharynx" ; rdfs:subClassOf obo:WBPhenotype_0000707, obo:WBPhenotype_0002553, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0003681 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001647 obo:IAO_0000115 "Any variation in the progression of the posterior portion of the pharynx over time compared to control. In C. elegans the posterior region includes the isthmus and terminal bulb (second bulb)." ; oboInOwl:hasNarrowSynonym "posterior pharynx abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001647" ; a owl:Class ; rdfs:label "posterior pharynx variant" ; rdfs:subClassOf obo:WBPhenotype_0000707 . obo:WBPhenotype_0001648 obo:IAO_0000115 "Embryos fail to generate cells that give rise to the posterior portion of the pharynx. In C. elegans, the MS blastomere- derived pharyngeal cells constitute the posterior portion of the pharynx." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001648" ; a owl:Class ; rdfs:label "no posterior pharynx" ; rdfs:subClassOf obo:WBPhenotype_0001646, obo:WBPhenotype_0001647 . obo:WBPhenotype_0001649 obo:IAO_0000115 "Animals fail to respond to the concentration of Fluorouracil (5-FU) that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. Elegans Fluorouracil induces germ cell death, inhibits embryogenesis and inhibits larval growth (depending on dose) in control animals." ; oboInOwl:hasExactSynonym "5 FU resistant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001649" ; a owl:Class ; rdfs:label "Fluorouracil resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_46345 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_46345 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001650 obo:IAO_0000115 "Germ cell death fails in response to the concentration of 5-FU that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans, in addition to cell death, 5-FU exposed animals exhibit condensed germ cell nuclei or unhealthy nuclei." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001650" ; a owl:Class ; rdfs:label "germ cell death response to 5 FU resistant" ; rdfs:subClassOf obo:WBPhenotype_0001649 . obo:WBPhenotype_0001651 obo:IAO_0000115 "Animals grow well during or after exposure to 5-FU under conditions where control animals are growth inhibited." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001651" ; a owl:Class ; rdfs:label "growth arrest response to 5 FU resistant" ; rdfs:subClassOf obo:WBPhenotype_0001649 . obo:WBPhenotype_0001652 obo:IAO_0000115 "Any variation in the process by which the gonad anchor cell makes contact with vulval cells in order to create a uterine-vulval connection. In C. elegans, this includes the loss of the basement membranes between these cells and the crossing of the basolateral portion of the anchor cell through this gap." ; oboInOwl:hasNarrowSynonym "anchor cell invasion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001652" ; a owl:Class ; rdfs:label "anchor cell invasion variant" ; rdfs:subClassOf obo:WBPhenotype_0000283 . obo:WBPhenotype_0001653 obo:IAO_0000115 "Animals exhibit variations in their response to cadmium compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "cadmium response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001653" ; a owl:Class ; rdfs:label "cadmium response variant" ; rdfs:subClassOf obo:WBPhenotype_0000591, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_22977 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_22977 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001654 obo:IAO_0000115 "Animals fail to respond to the concentration of cadmium that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to cadmium to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001654" ; a owl:Class ; rdfs:label "cadmium resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001653, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_22977 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_22977 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001655 obo:IAO_0000115 "Animals respond to cadmium at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001655" ; a owl:Class ; rdfs:label "cadmium hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001653, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_22977 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_22977 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001656 obo:IAO_0000115 "Any variation in the progression of the leader cell that guides and shapes the outgrowth of the gonad while crawling along the body wall to force the germline to extend into a long tubular shape over time from its formation to its mature structure compared to control." ; oboInOwl:hasNarrowSynonym "distal tip cell development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001656" ; a owl:Class ; rdfs:label "distal tip cell development variant" ; rdfs:subClassOf obo:WBPhenotype_0000399, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006865 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0006865 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001657 obo:IAO_0000115 "Animals exhibit variations in the specialized region of connection between two cells or between a cell and the extracellular matrix compared to control." ; oboInOwl:hasNarrowSynonym "cell junction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001657" ; a owl:Class ; rdfs:label "cell junction variant" ; rdfs:subClassOf obo:WBPhenotype_0001399, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030054 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0030054 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001658 obo:IAO_0000115 "Animals exhibit variations in the specialized region of connection between two cells compared to control." ; oboInOwl:hasNarrowSynonym "intercellular junction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "cell cell junction abnormal" ; oboInOwl:id "WBPhenotype:0001658" ; a owl:Class ; rdfs:label "intercellular junction variant" ; rdfs:subClassOf obo:WBPhenotype_0001657, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005911 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005911 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001659 obo:IAO_0000115 "Any variation in the form, structure or composition of the somatic gonad structure that connects the distal gonad arm to the uterus compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "spermatheca morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001659" ; a owl:Class ; rdfs:label "spermatheca morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000977, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005319 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005319 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001660 obo:IAO_0000115 "The two morphologically bilaterally symmetric gustatory neurons ASE left (ASEL) and ASE right (ASER) fail to undergo a left/right asymmetric diversification in cell fate." ; oboInOwl:hasNarrowSynonym "2ASEL", "2ASER" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001660" ; a owl:Class ; rdfs:label "loss of asymmetry ASE" ; rdfs:subClassOf obo:WBPhenotype_0001510, obo:WBPhenotype_0001512 . obo:WBPhenotype_0001661 obo:IAO_0000115 "The two morphologically bilaterally symmetric olfactory neurons AWC left (AWCL) and AWC right (AWCR) fail to undergo a left/right asymmetric diversification in cell fate." ; oboInOwl:hasNarrowSynonym "2 AWC off", "2 AWC on" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001661" ; a owl:Class ; rdfs:label "loss of asymmetry AWC" ; rdfs:subClassOf obo:WBPhenotype_0001510, obo:WBPhenotype_0001512 . obo:WBPhenotype_0001662 obo:IAO_0000115 "Any variation in the progression of the somatic gonad structure that connects the distal gonad arm to the uterus over time from an initial condition to a later condition compared to control animals." ; oboInOwl:hasNarrowSynonym "spermatheca development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001662" ; a owl:Class ; rdfs:label "spermatheca development variant" ; rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0000930, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005319 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0005319 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001663 obo:IAO_0000115 "Animals fail to respond to the levels of reactive oxygen species that elicit a response in control animals." ; oboInOwl:hasBroadSynonym "Oxr" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001663" ; a owl:Class ; rdfs:label "organism oxidative stress resistant" ; rdfs:subClassOf obo:WBPhenotype_0001620 . obo:WBPhenotype_0001664 obo:IAO_0000115 "The frequency of sex chromosome segregation is perturbed, resulting in the production of exceptional gametes (e.g. ova or sperm) and populations with a sex ratio altered from the rate of 1:500 as observed for control populations." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001664" ; a owl:Class ; rdfs:label "X chromosome nondisjunction" ; rdfs:subClassOf obo:WBPhenotype_0001174 . obo:WBPhenotype_0001665 obo:IAO_0000115 "Lower numbers of male progeny occur in the population compared to control populations. In C. elegans, the low incidence of males phenotype in a self-fertilizing hermaphrodite population is a result of an decrease in X chromosome nondisjunction." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001665" ; a owl:Class ; rdfs:label "low incidence male progeny" ; rdfs:subClassOf obo:WBPhenotype_0001664 . obo:WBPhenotype_0001666 obo:IAO_0000115 "Animals respond to iononizing radiation at a lower dose or a shorter exposure compared to control animals. Iononizing radiation has a wavelength in the 10 to 0.01 nanometer range. In C. elegans, increased sensitivity to X-ray irradiation is often observed as a decrease in survival upon exposure compared to control animals given the same treatment." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001666" ; a owl:Class ; rdfs:label "organism hypersensitive X ray irradiation" ; rdfs:subClassOf obo:WBPhenotype_0000276, obo:WBPhenotype_0000711 . obo:WBPhenotype_0001667 obo:IAO_0000115 "Animals respond to the chemical mutagen methyl methanesulfonate (MMS) a methanesulfonate ester and alkylating agent at a lower concentration or a shorter exposure compared to control animals. In C. elegans, increased sensitivity to MMS can be observed as a decrease in egg hatch upon acute exposure or inhibition of growth after chronic exposure compared to control animals given the same treatment." ; oboInOwl:hasExactSynonym "MMS hypersensitive" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001667" ; a owl:Class ; rdfs:label "methyl methanesulfonate hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000498, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25255 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25255 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001668 obo:IAO_0000115 "An increased number of oocytes are retained in the gonad without becoming endomitotic, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "oocyte number increased" ; oboInOwl:id "WBPhenotype:0001668" ; a owl:Class ; rdfs:label "oocyte accumulation" ; rdfs:subClassOf obo:WBPhenotype_0001260 . obo:WBPhenotype_0001669 obo:IAO_0000115 "Animals exhibit a variation in the ratio of synaptic vesicles per synapse of a neuron, compared to control animals." ; oboInOwl:hasNarrowSynonym "presynaptic vesicle number abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "synaptic vesicle number abnormal" ; oboInOwl:id "WBPhenotype:0001669" ; a owl:Class ; rdfs:label "presynaptic vesicle number variant" ; rdfs:subClassOf obo:WBPhenotype_0001321, obo:WBPhenotype_0001332, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008021 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008021 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001670 obo:IAO_0000115 "Animals exhibit an overall decrease in the quantity of synaptic vesicles at the synapse compared to control animals." ; oboInOwl:hasAlternativeId "WBPhenotype:0001322" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "synaptic vesicle number reduced" ; oboInOwl:id "WBPhenotype:0001670" ; a owl:Class ; rdfs:label "presynaptic vesicle number reduced" ; rdfs:subClassOf obo:WBPhenotype_0001669 . obo:WBPhenotype_0001671 obo:IAO_0000115 "Animals display variations in the distribution of spherical membrane-bound fluid-filled organelles, compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "vesicle organization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001671" ; a owl:Class ; rdfs:label "vesicle organization variant" ; rdfs:subClassOf obo:WBPhenotype_0000519, obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016050 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001672 obo:IAO_0000115 "Animals exhibit variations in the extension of the part of the axon that forms a bridge between body regions, compared to control animals." ; oboInOwl:hasNarrowSynonym "commisure growth abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001672" ; a owl:Class ; rdfs:label "commisure growth variant" ; rdfs:subClassOf obo:WBPhenotype_0001224 . obo:WBPhenotype_0001673 obo:IAO_0000115 "Animals exhibit variations in the processes that affect and monitor the activity of telomeric proteins and the length of telomeric DNA, which allow the chromosome to persist from generation to generation, compared to control." ; oboInOwl:hasNarrowSynonym "telomere homeostasis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001673" ; a owl:Class ; rdfs:label "telomere homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0000585 . obo:WBPhenotype_0001674 obo:IAO_0000115 "Animals exhibit variations in the sequence or organization of the components of the terminal region of its chromosome, (i.e. telomere, which serves to stabilize the chromosome) compared to control." ; oboInOwl:hasNarrowSynonym "telomere morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001674" ; a owl:Class ; rdfs:label "telomere morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001348, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000781 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000781 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001675 obo:IAO_0000115 "Males exhibit variations in the reproductive system, from its formation to the mature structure compared to control." ; oboInOwl:hasNarrowSynonym "male gonad development abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001675" ; a owl:Class ; rdfs:label "male gonad development variant" ; rdfs:subClassOf obo:WBPhenotype_0000613, obo:WBPhenotype_0000691, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006794 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:BFO_0000066 ; owl:someValuesFrom obo:WBbt_0006794 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001676 obo:IAO_0000115 "Animals exhibit variations in the structure or composition of any neuron within the class of sensory neurons responsible for relaying mechanical stimuli to the animal compared to control." ; oboInOwl:hasNarrowSynonym "touch receptor cell morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "mechanosensory neuron abnormal", "microtubule cell morphology abnormal" ; oboInOwl:id "WBPhenotype:0001676" ; a owl:Class ; rdfs:label "touch receptor cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000905, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005237 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005237 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001677 obo:IAO_0000115 "Animals display cuticle components displayed by animals of a different developmental stage, compared to control." ; oboInOwl:hasNarrowSynonym "Srf", "stage specific cuticle antigenicity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001677" ; a owl:Class ; rdfs:label "stage specific cuticle antigenicity variant" ; rdfs:subClassOf obo:WBPhenotype_0001687 . obo:WBPhenotype_0001678 obo:IAO_0000115 "Animals produce cuticles that vary in components such as proteins or carbohydrates, observed in control animals of the same developmental stage and raised under the same conditions." ; oboInOwl:hasNarrowSynonym "cuticle physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001678" ; a owl:Class ; rdfs:label "cuticle physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0001210 . obo:WBPhenotype_0001679 obo:IAO_0000115 "Neurons have more than one process extending from the cell body." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001679" ; a owl:Class ; rdfs:label "multipolar neuron" ; rdfs:subClassOf obo:WBPhenotype_0000905 . obo:WBPhenotype_0001680 obo:IAO_0000115 "Vulval precursor cells forgo further cell division and fuse to the hypodermis instead of adopting their intended fate (becoming primary, secondary or tertiary vulval cells)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "F fate abnormal", "VPC fused fate abnormal" ; oboInOwl:id "WBPhenotype:0001680" ; a owl:Class ; rdfs:label "adoption of fused vulval cell fate" ; rdfs:subClassOf obo:WBPhenotype_0001272 . obo:WBPhenotype_0001681 obo:IAO_0000115 "The alignment of the spindle relative to other cellular structures varies from that observed in control animals." ; oboInOwl:hasNarrowSynonym "spindle orientation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001681" ; a owl:Class ; rdfs:label "spindle orientation variant" ; rdfs:subClassOf obo:WBPhenotype_0002414, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000133 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000133 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005819 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001682 obo:IAO_0000115 "Organisms respond to UV at a higer dose or a longer exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001682" ; a owl:Class ; rdfs:label "organism UV resistant" ; rdfs:subClassOf obo:WBPhenotype_0000143 . obo:WBPhenotype_0001683 obo:IAO_0000115 "Variations that specifically disrupt sperm production in XX hermaphrodites. By contrast, spermatogenesis in XO males remains unaffected." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001683" ; a owl:Class ; rdfs:label "spermatogenesis defective hermaphrodite" ; rdfs:subClassOf obo:WBPhenotype_0000670 . obo:WBPhenotype_0001684 obo:IAO_0000115 "The rates of synaptic vesicle exocytosis and endocytosis vary from that observed in control animals." ; oboInOwl:hasNarrowSynonym "synaptic vesicle homeostasis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001684" ; a owl:Class ; rdfs:label "synaptic vesicle homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0000846 . obo:WBPhenotype_0001685 obo:IAO_0000115 "The region opposite to the presynaptic region deviates in the structure, configuration or ratio of its components specific for receiving signals from the other side of the synapse compared to control." ; oboInOwl:hasNarrowSynonym "postsynaptic region morphology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001685" ; a owl:Class ; rdfs:label "postsynaptic region morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000616 . obo:WBPhenotype_0001686 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process in the region, opposite to the presynaptic region, which is required for receiving signals from the other side of the synapse compared to control." ; oboInOwl:hasNarrowSynonym "postsynaptic region physiology abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001686" ; a owl:Class ; rdfs:label "postsynaptic region physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000584 . obo:WBPhenotype_0001687 obo:IAO_0000115 "Cuticles of animals or cuticular extracts exhibit an altered pattern of antibody binding compared to Bristol N2 animals of the same developmental stage." ; oboInOwl:hasBroadSynonym "Srf" ; oboInOwl:hasNarrowSynonym "surface antigenicity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001687" ; a owl:Class ; rdfs:label "surface antigenicity variant" ; rdfs:subClassOf obo:WBPhenotype_0001688 . obo:WBPhenotype_0001688 obo:IAO_0000115 "The electron dense, amorphous envelope that comprises the outermost layer of the cuticle varies in composition from that observed in control animals of the same developmental stage. The integrity of the surface coat is often revealed by an altered antigenicity or biochemical make up." ; oboInOwl:hasBroadSynonym "Srf" ; oboInOwl:hasNarrowSynonym "surface coat abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001688" ; a owl:Class ; rdfs:label "surface coat variant" ; rdfs:subClassOf obo:WBPhenotype_0000201, obo:WBPhenotype_0001678 . obo:WBPhenotype_0001689 obo:IAO_0000115 "Cuticles or cuticular extracts do not bind antibodies that are observed to bind the surfaces or cuticular extracts of Bristol N2 animals of the same developmental stage." ; oboInOwl:hasNarrowSynonym "Srf" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001689" ; a owl:Class ; rdfs:label "surface antigen negative" ; rdfs:subClassOf obo:WBPhenotype_0001687 . obo:WBPhenotype_0001690 obo:IAO_0000115 "Animals display surface antigens throughout all larval stages, unlike Bristol N2 worms, which display the antigens only during one larval stage." ; oboInOwl:hasBroadSynonym "Cld" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001690" ; a owl:Class ; rdfs:label "constitutive larval display" ; rdfs:subClassOf obo:WBPhenotype_0001677 . obo:WBPhenotype_0001691 obo:IAO_0000115 "Germ nuclei are misplaced in the gonad and are observed in the rachis. Sheath cells are observed protruding between these nuclei. Meiotic or mitotic specification of germ nuclei is not affected." ; oboInOwl:hasNarrowSynonym "germ line morphogenesis(Glm)" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001691" ; a owl:Class ; rdfs:label "germ nuclei rachis" ; rdfs:subClassOf obo:WBPhenotype_0001940 . obo:WBPhenotype_0001692 obo:IAO_0000115 "Animals are not induced to display surface antigens by exposure to pheromone as observed for Bristol N2 animals." ; oboInOwl:hasExactSynonym "ILD abnormal" ; oboInOwl:hasNarrowSynonym "pheromone induced larval display abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "induced larval display abnormal" ; oboInOwl:id "WBPhenotype:0001692" ; a owl:Class ; rdfs:label "pheromone induced larval display defective" ; rdfs:subClassOf obo:WBPhenotype_0001687 . obo:WBPhenotype_0001693 obo:IAO_0000115 "Males have alae that extend into the tail region. Alae are small linear ridges running along the lateral lines of the cuticle. In C. elegans alae do not extend into the tail region (Wormatlas)." ; oboInOwl:hasBroadSynonym "Pal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001693" ; a owl:Class ; rdfs:label "male posterior alae" ; rdfs:subClassOf obo:WBPhenotype_0000202, obo:WBPhenotype_0001240 . obo:WBPhenotype_0001694 obo:IAO_0000115 "Hermaphrodites continue to produce sperm past the time at which the transition to oogenesis normally occurs. Thus, germ cells that would normally become oocytes are transformed into sperm instead." ; oboInOwl:hasNarrowSynonym "spermatogenesis to oogenesis switch abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001694" ; a owl:Class ; rdfs:label "spermatogenesis to oogenesis switch defective" ; rdfs:subClassOf obo:WBPhenotype_0001572 . obo:WBPhenotype_0001695 obo:IAO_0000115 "Animals exhibit variations in their catalytic ability the transfer glycolsyl groups from one compound (donor) to another (acceptor) often measured by a reduction in the amount of glycosylated products compared to that observed in control animals of the same developmental stage." ; oboInOwl:hasNarrowSynonym "glycosyltransferase activity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001695" ; a owl:Class ; rdfs:label "glycosyltransferase activity variant" ; rdfs:subClassOf obo:WBPhenotype_0000733, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016757 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016757 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001696 obo:IAO_0000115 "Animals exhibit variations in the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones compared to control." ; oboInOwl:hasNarrowSynonym "biosynthesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001696" ; a owl:Class ; rdfs:label "biosynthesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000463, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009058 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009058 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001697 obo:IAO_0000115 "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of chondroitin sulfate compared to control." ; oboInOwl:hasNarrowSynonym "chondroitin biosynthesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001697" ; a owl:Class ; rdfs:label "chondroitin biosynthesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001696 . obo:WBPhenotype_0001698 obo:IAO_0000115 "Animals exhibit variations in the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan compared to control." ; oboInOwl:hasNarrowSynonym "heparan sulfate biosynthesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001698" ; a owl:Class ; rdfs:label "heparan sulfate biosynthesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001696 . obo:WBPhenotype_0001699 obo:IAO_0000115 "Specific body regions of an animal display variations in movement compared to that observed in control animals." ; oboInOwl:hasNarrowSynonym "localized movement abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001699" ; a owl:Class ; rdfs:label "localized movement variant" ; rdfs:subClassOf obo:WBPhenotype_0001206 . obo:WBPhenotype_0001700 obo:IAO_0000115 "Animals exhibit variations in movement in liquid from that observed for control animals." ; oboInOwl:hasNarrowSynonym "swimming abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "movement in liquid abnormal", "thrashing abnormal" ; oboInOwl:id "WBPhenotype:0001700" ; a owl:Class ; rdfs:label "swimming variant" ; rdfs:subClassOf obo:WBPhenotype_0001206 . obo:WBPhenotype_0001701 obo:IAO_0000115 "Animals exhibit uncharacteristic muscle contractions during the process by which they travel from one location to another." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "convulsive" ; oboInOwl:id "WBPhenotype:0001701" ; a owl:Class ; rdfs:label "spastic locomotion" ; rdfs:subClassOf obo:WBPhenotype_0004017 . obo:WBPhenotype_0001702 obo:IAO_0000115 "Animals exhibit variations in the directional changes that separate consecutive runs, from that observed for control animals. In C. elegans, these aberrations include variations in the form or extent of omega turns or reversals (shifts from forward to backward movements)." ; oboInOwl:hasNarrowSynonym "directionality abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "reversal abnormal", "turning abnormal" ; oboInOwl:id "WBPhenotype:0001702" ; a owl:Class ; rdfs:label "directionality variant" ; rdfs:subClassOf obo:WBPhenotype_0004017 . obo:WBPhenotype_0001703 obo:IAO_0000115 "Any variation in the maximum ventral and dorsal flex of the animal compared to control animals." ; oboInOwl:hasNarrowSynonym "body bend abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001703" ; a owl:Class ; rdfs:label "body bend variant" ; rdfs:subClassOf obo:WBPhenotype_0004018 . obo:WBPhenotype_0001704 obo:IAO_0000115 "Alae contain more cuticular ridges than control animals. In C. elegans alae are composed of three cuticular ridges." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001704" ; a owl:Class ; rdfs:label "multiple alae" ; rdfs:subClassOf obo:WBPhenotype_0001412 . obo:WBPhenotype_0001705 obo:IAO_0000115 "The directed movement of molecules between the nucleus and the cytoplasm is impaired." ; oboInOwl:hasNarrowSynonym "nucleocytoplasmic transport abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001705" ; a owl:Class ; rdfs:label "nucleocytoplasmic transport defective" ; rdfs:subClassOf obo:WBPhenotype_0001283, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0006913 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0006913 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001706 obo:IAO_0000115 "The directed movement of substances out of the nucleus is impaired." ; oboInOwl:hasNarrowSynonym "nuclear export abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001706" ; a owl:Class ; rdfs:label "nuclear export defective" ; rdfs:subClassOf obo:WBPhenotype_0001705 . obo:WBPhenotype_0001707 obo:IAO_0000115 "The directed movement of substances into the nucleus is impaired." ; oboInOwl:hasNarrowSynonym "nuclear import abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001707" ; a owl:Class ; rdfs:label "nuclear import defective" ; rdfs:subClassOf obo:WBPhenotype_0001705, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0051170 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0051170 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001708 obo:IAO_0000115 "The directed movement of a protein from the nucleus into the cytoplasm is impaired." ; oboInOwl:hasNarrowSynonym "protein export from nucleus abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001708" ; a owl:Class ; rdfs:label "protein export from nucleus defective" ; rdfs:subClassOf obo:WBPhenotype_0001706 . obo:WBPhenotype_0001709 obo:IAO_0000115 "Animals exhibit variations in light/dark cycle recurrence of reactions to stress conditions compared to that observed for control animals." ; oboInOwl:hasNarrowSynonym "rhythmic tolerance to stress abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "circadian variation in stress tolerance abnormal" ; oboInOwl:id "WBPhenotype:0001709" ; a owl:Class ; rdfs:label "rhythmic tolerance to stress variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, obo:WBPhenotype_0001711 . obo:WBPhenotype_0001710 obo:IAO_0000115 "Animals exhibit variations in light/dark cycle recurrence of reactions to osmotic stress compared to that observed for control animals." ; oboInOwl:hasNarrowSynonym "rhythmic tolerance to osmotic stress abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001710" ; a owl:Class ; rdfs:label "rhythmic tolerance to osmotic stress variant" ; rdfs:subClassOf obo:WBPhenotype_0001709 . obo:WBPhenotype_0001711 obo:IAO_0000115 "Animals exhibit variations in actions or responses that occur with measurable periodicity, from that observed for control animals." ; oboInOwl:hasNarrowSynonym "rhythmic behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001711" ; a owl:Class ; rdfs:label "rhythmic behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007622 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001712 obo:IAO_0000115 "Animals exhibit variations in the actions or reactions that recur with a periodicity associated with light/dark cycles, compared to control." ; oboInOwl:hasNarrowSynonym "circadian rhythm behavior abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001712" ; a owl:Class ; rdfs:label "circadian rhythm behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0001711, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048512 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048512 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001713 obo:IAO_0000115 "Animals exhibit variations in locomotor activity during its light/dark cycle from that observed in control animals." ; oboInOwl:hasNarrowSynonym "locomotory rhythm abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001713" ; a owl:Class ; rdfs:label "locomotory rhythm variant" ; rdfs:subClassOf obo:WBPhenotype_0001711 . obo:WBPhenotype_0001714 obo:IAO_0000115 "Animals exhibit variations in turning bouts, consisting of one or more sharp turning events separating consecutive runs, which serve to orient the animal within a gradient, compared to control." ; oboInOwl:hasNarrowSynonym "pirouette abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001714" ; a owl:Class ; rdfs:label "pirouette variant" ; rdfs:subClassOf obo:WBPhenotype_0002311 . obo:WBPhenotype_0001715 obo:IAO_0000115 "Animals exhibit variations in the number of directional changes over time from that observed for control animals." ; oboInOwl:hasNarrowSynonym "frequency of directionality abnormal", "pirouette frequency abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001715" ; a owl:Class ; rdfs:label "pirouette frequency variant" ; rdfs:subClassOf obo:WBPhenotype_0001714 . obo:WBPhenotype_0001716 obo:IAO_0000115 "Animals exhibit variations in the velocity of forward translocation of any point along the animal's track from that observed for control animals." ; oboInOwl:hasNarrowSynonym "forward point velocity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001716" ; a owl:Class ; rdfs:label "forward point velocity variant" ; rdfs:subClassOf obo:WBPhenotype_0004025 . obo:WBPhenotype_0001717 obo:IAO_0000115 "Animals exhibit variations in the translocation of the mean position of the rear two-thirds (centroid position) of the animal over time, from that observed for control animals." ; oboInOwl:hasNarrowSynonym "centroid velocity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001717" ; a owl:Class ; rdfs:label "centroid velocity variant" ; rdfs:subClassOf obo:WBPhenotype_0004025 . obo:WBPhenotype_0001718 obo:IAO_0000115 "Animals exhibit variations in the mean translocation of the points along the animal's track compared to control." ; oboInOwl:hasNarrowSynonym "instantaneous velocity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001718" ; a owl:Class ; rdfs:label "instantaneous velocity variant" ; rdfs:subClassOf obo:WBPhenotype_0004025 . obo:WBPhenotype_0001719 obo:IAO_0000115 "Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones." ; oboInOwl:hasNarrowSynonym "unfolded protein response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ER unfolded protein response abnormal", "UPR", "unfolded protein response" ; oboInOwl:id "WBPhenotype:0001719" ; a owl:Class ; rdfs:label "unfolded protein response variant" ; rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0000523, obo:WBPhenotype_0001644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006986 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006986 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001720 obo:IAO_0000115 "Spermatozoa do not crawl back into the spermatheca after being swept into the uterus by passing oocytes." ; oboInOwl:hasNarrowSynonym "spermatozoa retro location abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "spermatheca homing abnormal" ; oboInOwl:id "WBPhenotype:0001720" ; a owl:Class ; rdfs:label "spermatozoa retro location defective" ; rdfs:subClassOf obo:WBPhenotype_0000389, obo:WBPhenotype_0001386 . obo:WBPhenotype_0001721 obo:IAO_0000115 "Animals exhibit variations in the extent of pathogen invasion into the pharynx compared to control. This is often measured as the percentage of animals exhibiting a pathogen-invaded pharynx within a given population." ; oboInOwl:hasNarrowSynonym "pathogen infected pharynx abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001721" ; a owl:Class ; rdfs:label "pathogen infected pharynx variant" ; rdfs:subClassOf obo:WBPhenotype_0001012 . obo:WBPhenotype_0001722 obo:IAO_0000115 "Animals exhibit a greater extent of pathogen invasion into the pharynx compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001722" ; a owl:Class ; rdfs:label "pathogen infected pharynx increase" ; rdfs:subClassOf obo:WBPhenotype_0001721 . obo:WBPhenotype_0001723 obo:IAO_0000115 "Animals exhibit a lesser extent of pathogen invasion into the pharynx compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001723" ; a owl:Class ; rdfs:label "pathogen infected pharynx decrease" ; rdfs:subClassOf obo:WBPhenotype_0001721 . obo:WBPhenotype_0001724 obo:IAO_0000115 "Animals respond to tunicamycin at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001724" ; a owl:Class ; rdfs:label "tunicamycin hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000359, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_29699 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_29699 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001725 obo:IAO_0000115 "Cells exhibit variations in the response to osmotic stress compared to control. In C. elegans, exposure to stress-inducing osmotic conditions invokes cellular changes, including transcriptional up or down-regulation of genes." ; oboInOwl:hasNarrowSynonym "osmotic stress response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001725" ; a owl:Class ; rdfs:label "cellular osmotic stress response variant" ; rdfs:subClassOf obo:WBPhenotype_0000142, obo:WBPhenotype_0000523, obo:WBPhenotype_0000876, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0071470 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0071470 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001726 obo:IAO_0000115 "Animals vary in the distance between anterior and posterior ends of the animal from that observed in control animals." ; oboInOwl:hasNarrowSynonym "body length abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001726" ; a owl:Class ; rdfs:label "body length variant" ; rdfs:subClassOf obo:WBPhenotype_0000231 . obo:WBPhenotype_0001727 obo:IAO_0000115 "Animals vary in the distance between dorsal and ventral sides when measured across the body at right angles to the length, from that observed in control animals." ; oboInOwl:hasNarrowSynonym "body width abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001727" ; a owl:Class ; rdfs:label "body width variant" ; rdfs:subClassOf obo:WBPhenotype_0000231 . obo:WBPhenotype_0001728 obo:IAO_0000115 "Males differ from control animals in their ability to form copulatory plugs or their placement of these plugs. In C. elegans, males of the Hawaiian strain (CB4856) typically form mating plugs." ; oboInOwl:hasNarrowSynonym "mating plug production abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001728" ; a owl:Class ; rdfs:label "mating plug production variant" ; rdfs:subClassOf obo:WBPhenotype_0000928 . obo:WBPhenotype_0001729 obo:IAO_0000115 "Males form copulatory mating plugs." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "mating plug plus", "plug plus" ; oboInOwl:id "WBPhenotype:0001729" ; a owl:Class ; rdfs:label "mating plug produced" ; rdfs:subClassOf obo:WBPhenotype_0001728 . obo:WBPhenotype_0001730 obo:IAO_0000115 "Males do not form copulatory mating plug." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "mating plug minus", "plug minus" ; oboInOwl:id "WBPhenotype:0001730" ; a owl:Class ; rdfs:label "mating plug deficient" ; rdfs:subClassOf obo:WBPhenotype_0001728 . obo:WBPhenotype_0001731 obo:IAO_0000115 "Animals exhibit variations in the duration of the trajectory of the forward track in a thermal gradient compared to control." ; oboInOwl:hasNarrowSynonym "thermal bias in tracking abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "cryophilic bias" ; oboInOwl:id "WBPhenotype:0001731" ; a owl:Class ; rdfs:label "thermal bias in tracking variant" ; rdfs:subClassOf obo:WBPhenotype_0000478 . obo:WBPhenotype_0001732 obo:IAO_0000115 "Animals exhibit variations in their response and ability to survive over a range of pH conditions compared to control." ; oboInOwl:hasNarrowSynonym "organism response to pH abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001732" ; a owl:Class ; rdfs:label "organism response to pH variant" ; rdfs:subClassOf obo:WBPhenotype_0000067, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009268 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009268 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001733 obo:IAO_0000115 "Animals treated with pheromone do not exhibit a decrease in pumping rate similar to that observed for control animals." ; oboInOwl:hasNarrowSynonym "pheromone suppressed pumping abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001733" ; a owl:Class ; rdfs:label "pheromone suppressed pumping defective" ; rdfs:subClassOf obo:WBPhenotype_0001287 . obo:WBPhenotype_0001734 obo:IAO_0000115 "Animals deprived of food do not exhibit a decrease in pumping rate similar to that observed for control animals." ; oboInOwl:hasNarrowSynonym "starvation suppressed pumping abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "food deprived suppression of pumping abnormal" ; oboInOwl:id "WBPhenotype:0001734" ; a owl:Class ; rdfs:label "starvation suppressed pumping defective" ; rdfs:subClassOf obo:WBPhenotype_0001287 . obo:WBPhenotype_0001735 obo:IAO_0000115 "Animals exhibit variations in the frequency, rate or extent of muscle contraction compared to control animals." ; oboInOwl:hasNarrowSynonym "muscle cell activity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001735" ; a owl:Class ; rdfs:label "muscle cell activity variant" ; rdfs:subClassOf obo:WBPhenotype_0000990 . obo:WBPhenotype_0001736 obo:IAO_0000115 "Failure to execute the characteristic response to acetate compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001736" ; a owl:Class ; rdfs:label "acetate chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0000015 . obo:WBPhenotype_0001737 obo:IAO_0000115 "Animals are unable to locate the gradient peak of a water soluble compound, which was generated on a uniform concentration of another compound." ; oboInOwl:hasNarrowSynonym "aqueous compound discrimination abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001737" ; a owl:Class ; rdfs:label "aqueous compound discrimination defective" ; rdfs:subClassOf obo:WBPhenotype_0001443 . obo:WBPhenotype_0001738 obo:IAO_0000115 "Failure to execute the characteristic response to ammonium compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001738" ; a owl:Class ; rdfs:label "ammonium chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0000015 . obo:WBPhenotype_0001739 obo:IAO_0000115 "Any variation in an organism's decline over time from its optimal fertility and viability compared to control animals." ; oboInOwl:hasNarrowSynonym "aging abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001739" ; a owl:Class ; rdfs:label "aging variant" ; rdfs:subClassOf obo:WBPhenotype_0000576, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007568 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007568 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001740 obo:IAO_0000115 "Any variation in the preprogrammed process that occurs in an organism that is associated with the dismantling of an organ and an overall decline in metabolic function compared to control animals. This may include variations in the rate or extent of morphological disarray and of the breakdown or organelles, membranes and other cellular components." ; oboInOwl:hasNarrowSynonym "organ senescence abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001740" ; a owl:Class ; rdfs:label "organ senescence variant" ; rdfs:subClassOf obo:WBPhenotype_0000530, obo:WBPhenotype_0000534, obo:WBPhenotype_0000575, obo:WBPhenotype_0001739, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010260 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010260 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001741 obo:IAO_0000115 "Males exhibit spicule-muscle seizures leading to inappropriately timed protraction compared to control." ; oboInOwl:hasBroadSynonym "Prc" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "precocious spicule protraction", "protraction constitutive" ; oboInOwl:id "WBPhenotype:0001741" ; a owl:Class ; rdfs:label "spontaneous spicule protraction" ; rdfs:subClassOf obo:WBPhenotype_0002443 . obo:WBPhenotype_0001742 obo:IAO_0000115 "The endogenous anabolism of any lipid species has been increased compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001742" ; a owl:Class ; rdfs:label "lipid synthesis increased" ; rdfs:subClassOf obo:WBPhenotype_0000725, obo:WBPhenotype_0001696, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008610 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008610 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001743 obo:IAO_0000115 "Any variation in the division of the eukaryotic cell nucleus to produce two daughter nuclei that contain the identical chromosome complement of their mother compared to control." ; oboInOwl:hasNarrowSynonym "mitosis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001743" ; a owl:Class ; rdfs:label "mitosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000746, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1903047 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1903047 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001744 obo:IAO_0000115 "Any variation in the attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix compared to control." ; oboInOwl:hasNarrowSynonym "cell adhesion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001744" ; a owl:Class ; rdfs:label "cell adhesion variant" ; rdfs:subClassOf obo:WBPhenotype_0000519, obo:WBPhenotype_0001657, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007155 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007155 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001745 obo:IAO_0000115 "Any variation in a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments compared to control." ; oboInOwl:hasNarrowSynonym "adherens junction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001745" ; a owl:Class ; rdfs:label "adherens junction variant" ; rdfs:subClassOf obo:WBPhenotype_0001658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0005912 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0005912 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001746 obo:IAO_0000115 "Any perturbation in the belt-like region of very close contact between the plasma membranes of adjacent cells that results in the complete occlusion of the intercellular space." ; oboInOwl:hasExactSynonym "zonula occludens abnormal" ; oboInOwl:hasNarrowSynonym "tight junction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001746" ; a owl:Class ; rdfs:label "tight junction defective" ; rdfs:subClassOf obo:WBPhenotype_0001658, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0070160 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0070160 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001747 obo:IAO_0000115 "Animals exhibit variations in the change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus compared to control." ; oboInOwl:hasNarrowSynonym "zinc response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001747" ; a owl:Class ; rdfs:label "zinc response variant" ; rdfs:subClassOf obo:WBPhenotype_0000591, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_30185 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000077 [ a owl:Restriction ; owl:onProperty obo:BFO_0000070 ; owl:someValuesFrom obo:CHEBI_30185 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001748 obo:IAO_0000115 "The pharynx or pharyngeal muscle does not form a functional connection to the mouth or buccal cavity." ; oboInOwl:hasExactSynonym "Pun" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001748" ; a owl:Class ; rdfs:label "pharynx unattached" ; rdfs:subClassOf obo:WBPhenotype_0000707 . obo:WBPhenotype_0001749 obo:IAO_0000115 "The toxic response to zinc occurs at a lower concentration or a shorter exposure compared to control animals. In C. elegans hypersensitive animals exhibit delayed development or lethality at concentrations of zinc (e.g. ZnSO4), which has little or no effect on control worms." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001749" ; a owl:Class ; rdfs:label "zinc toxicity hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001747, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27363 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27363 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001750 obo:IAO_0000115 "Animals fail to exhibit toxicity to the concentration of zinc that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to zinc include delayed development or lethality." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001750" ; a owl:Class ; rdfs:label "zinc toxicity resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001747, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27363 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27363 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001751 obo:IAO_0000115 "Animals exhibit increased lethality as a result of exposure to environments with a higher solute concentration than their own internal environment, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Hos", "hypertonic sensitive" ; oboInOwl:id "WBPhenotype:0001751" ; a owl:Class ; rdfs:label "organism hypertonic lethality increased" ; rdfs:subClassOf obo:WBPhenotype_0000141, obo:WBPhenotype_0000876 . obo:WBPhenotype_0001752 obo:IAO_0000115 "Animals exhibit variations in vesicle-based directed movement of substances into, out of, or within a cell compared to control." ; oboInOwl:hasNarrowSynonym "vesicle trafficking abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001752" ; a owl:Class ; rdfs:label "vesicle trafficking variant" ; rdfs:subClassOf obo:WBPhenotype_0000536, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016192 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016192 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001753 obo:IAO_0000115 "Animals exhibit intensified accumulation of fluids or fluorescent markers etc. within their coelomocytes compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001753" ; a owl:Class ; rdfs:label "coelomocyte uptake increased" ; rdfs:subClassOf obo:WBPhenotype_0001423 . obo:WBPhenotype_0001754 obo:IAO_0000115 "Contents of endosomes fail to be transported to lysosomal compartments." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001754" ; a owl:Class ; rdfs:label "endosome to lysosome trafficking defective" ; rdfs:subClassOf obo:WBPhenotype_0001421 . obo:WBPhenotype_0001755 obo:IAO_0000115 "Animals do not arrest mitotic germ cell division, as control animals, when treated with UV radiation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001755" ; a owl:Class ; rdfs:label "UV induced mitotic germ cell arrest defective" ; rdfs:subClassOf obo:WBPhenotype_0000100 . obo:WBPhenotype_0001756 obo:IAO_0000115 "Programmed cell death caused by UV radiation is reduced compared to control animals. In C. elegans, this is often measured in the pachytene region of the gonad." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001756" ; a owl:Class ; rdfs:label "UV induced apoptosis decreased" ; rdfs:subClassOf obo:WBPhenotype_0000100 . obo:WBPhenotype_0001757 obo:IAO_0000115 "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of signalling peptides in the organism compared to control." ; oboInOwl:hasNarrowSynonym "neuropeptide metabolism abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001757" ; a owl:Class ; rdfs:label "neuropeptide metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000027 . obo:WBPhenotype_0001758 obo:IAO_0000115 "Variations in the chemical reactions and pathways involved in the formation and maturation of specialized peptidergic neurotransmitters encoded as preproproteins that are posttranslationally processed to yield bioactive neuropeptides compared to control (Wormatlas)." ; oboInOwl:hasNarrowSynonym "neuropeptide processing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001758" ; a owl:Class ; rdfs:label "neuropeptide processing variant" ; rdfs:subClassOf obo:WBPhenotype_0000122, obo:WBPhenotype_0001757 . obo:WBPhenotype_0001759 obo:IAO_0000115 "Variations in the biogenesis or stability of the 21U-RNA class of molecules compared to control. Molecules are classified as 21U-RNA based on the presence of a 5'U and a conserved upstream motif, which may specify the production of these molecules, in addition these molecules are typically 21nt in length." ; oboInOwl:hasNarrowSynonym "21U RNA expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "piRNA expression abnormal" ; oboInOwl:id "WBPhenotype:0001759" ; a owl:Class ; rdfs:label "21U RNA expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000113 . obo:WBPhenotype_0001760 obo:IAO_0000115 "Animals exhibit an increase in the rate of deletion events in mono-G or G-rich tracts within the genome compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001760" ; a owl:Class ; rdfs:label "G tract instability" ; rdfs:subClassOf obo:WBPhenotype_0000000 . obo:WBPhenotype_0001761 obo:IAO_0000115 "Regulated ventral midline crossing by axons vary either in the frequency of crossing events or the maintenance through development of process positions compared to control." ; oboInOwl:hasNarrowSynonym "axon midline crossing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001761" ; a owl:Class ; rdfs:label "axon midline crossing variant" ; rdfs:subClassOf obo:WBPhenotype_0000384 . obo:WBPhenotype_0001762 obo:IAO_0000115 "Yolk is not taken up by oocytes in the same manner or to the same degree as observed for control animals. This often leads to an accumulation of yolk in the pseudocoelom." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001762" ; a owl:Class ; rdfs:label "uptake of yolk defective" ; rdfs:subClassOf obo:WBPhenotype_0001422, obo:WBPhenotype_0001424 . obo:WBPhenotype_0001763 obo:IAO_0000115 "Uptake of subtances from the intestine is altered from that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001763" ; a owl:Class ; rdfs:label "uptake by intestinal cell defective" ; rdfs:subClassOf obo:WBPhenotype_0000986 . obo:WBPhenotype_0001764 obo:IAO_0000115 "Animals exhibit variations in their response to carbon dioxide compared to control." ; oboInOwl:hasNarrowSynonym "carbon dioxide response abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001764" ; a owl:Class ; rdfs:label "carbon dioxide response variant" ; rdfs:subClassOf obo:WBPhenotype_0000523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010037 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010037 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001765 obo:IAO_0000115 "Variations in the characteristic movement away from specific CO2 levels compared to control. C. elegans avoids high levels of CO2." ; oboInOwl:hasNarrowSynonym "carbon dioxide avoidance abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "CO2 avoidance abnormal", "Cdad" ; oboInOwl:id "WBPhenotype:0001765" ; a owl:Class ; rdfs:label "carbon dioxide avoidance variant" ; rdfs:subClassOf obo:WBPhenotype_0001764 . obo:WBPhenotype_0001766 obo:IAO_0000115 "Animals are more sensitive to the reduction of cholesterol in the environment compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001766" ; a owl:Class ; rdfs:label "cholesterol depletion hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000725, obo:WBPhenotype_0002525 . obo:WBPhenotype_0001767 obo:IAO_0000115 "Outgrowth of the commissure occurs on the side of the body different from that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001767" ; a owl:Class ; rdfs:label "commissure handedness defective" ; rdfs:subClassOf obo:WBPhenotype_0000181, obo:WBPhenotype_0000384 . obo:WBPhenotype_0001768 obo:IAO_0000115 "Variations in the quantity of circumferential axonal tracts from the number observed in control animals." ; oboInOwl:hasNarrowSynonym "commissure number abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001768" ; a owl:Class ; rdfs:label "commissure number variant" ; rdfs:subClassOf obo:WBPhenotype_0001226 . obo:WBPhenotype_0001769 obo:IAO_0000115 "Animals fail to silence cytoplasmic-localized RNAs. Nuclear-localized RNAs may still be sensitive to RNAi." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001769" ; a owl:Class ; rdfs:label "cytoplasmic RNAi defective" ; rdfs:subClassOf obo:WBPhenotype_0000743 . obo:WBPhenotype_0001770 obo:IAO_0000115 "Animals exhibit variations in their selective interactions with small interfering RNA molecules compared to control." ; oboInOwl:hasNarrowSynonym "endo siRNA binding abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001770" ; a owl:Class ; rdfs:label "endo siRNA binding variant" ; rdfs:subClassOf obo:WBPhenotype_0000743 . obo:WBPhenotype_0001771 obo:IAO_0000115 "Animals exhibit variations in the length or amount of any endogenous small interfering RNA molecule populations compared to control." ; oboInOwl:hasNarrowSynonym "endo siRNA production abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001771" ; a owl:Class ; rdfs:label "endo siRNA production variant" ; rdfs:subClassOf obo:WBPhenotype_0000743 . obo:WBPhenotype_0001772 obo:IAO_0000115 "Animals exhibit an increase in the levels of transposase mRNA, from endogenous transposons, over that measured in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001772" ; a owl:Class ; rdfs:label "endogenous transposase levels increased" ; rdfs:subClassOf obo:WBPhenotype_0000745 . obo:WBPhenotype_0001773 obo:IAO_0000115 "Animals do not exhibit an increase in speed when placed in an environment that relies on a combination of swimming and crawling behaviors compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001773" ; a owl:Class ; rdfs:label "enhanced locomotion defective" ; rdfs:subClassOf obo:WBPhenotype_0001206 . obo:WBPhenotype_0001774 obo:IAO_0000115 "An epidermal enclosure defect that results in internal organs lying on the outside of the embryo." ; oboInOwl:hasExactSynonym "Gex" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001774" ; a owl:Class ; rdfs:label "gut on the exterior" ; rdfs:subClassOf obo:WBPhenotype_0000047 . obo:WBPhenotype_0001775 obo:IAO_0000115 "Pre-treatment with stress-inducing temperatures does not result in a life-span extension as it does in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001775" ; a owl:Class ; rdfs:label "hormetic temperature induced life span extension defective" ; rdfs:subClassOf obo:WBPhenotype_0000039, obo:WBPhenotype_0000146 . obo:WBPhenotype_0001776 obo:IAO_0000115 "Variations in the biogenesis and stability of the small interfering class of RNA molecules compared to control. In C. elegans these molecules are antisense to mRNA's and may be processed from long double-stranded RNA." ; oboInOwl:hasNarrowSynonym "siRNA expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001776" ; a owl:Class ; rdfs:label "siRNA expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000113 . obo:WBPhenotype_0001777 obo:IAO_0000115 "Animals exhibit an increase in the levels of nuclear mRNA species compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001777" ; a owl:Class ; rdfs:label "pre mRNA levels increased" ; rdfs:subClassOf obo:WBPhenotype_0000113 . obo:WBPhenotype_0001778 obo:IAO_0000115 "Animals fail to silence nuclear-localized RNAs. Animals still retain sensitivity to RNAi for those RNAs located outside of the nucleus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001778" ; a owl:Class ; rdfs:label "nuclear RNAi defective" ; rdfs:subClassOf obo:WBPhenotype_0000743 . obo:WBPhenotype_0001779 obo:IAO_0000115 "Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts." ; oboInOwl:hasNarrowSynonym "miRNA expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001779" ; a owl:Class ; rdfs:label "miRNA expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000113 . obo:WBPhenotype_0001780 obo:IAO_0000115 "Variations in the behavioral plasticity induced by the integration of two sensory signals compared to control. In C. elegans animals exhibit enhancement of butanone chemotaxis by preexposure to butanone and food." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001780" ; a owl:Class ; rdfs:label "associative learning variant" ; rdfs:subClassOf obo:WBPhenotype_0000517, obo:WBPhenotype_0000738, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008306 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0008306 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001781 obo:IAO_0000115 "Animals are more susceptible than control animals to the effects of a nucleic acid damaging agent. This increased susceptibility is often measured by an increase in the rate of spontaneous mutations or an increased lethality." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001781" ; a owl:Class ; rdfs:label "hypersensitivity to mutagen" ; rdfs:subClassOf obo:WBPhenotype_0000577, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25435 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25435 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001782 obo:IAO_0000115 "Response to trace levels of oxygen is reduced or weakened compared to the response of control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001782" ; a owl:Class ; rdfs:label "anoxia response attenuated" ; rdfs:subClassOf obo:WBPhenotype_0002424 . obo:WBPhenotype_0001783 obo:IAO_0000115 "Animals exhibit variations in the actions of a channel that catalyses the transmembrane transfer of a cation when acetylcholine has been bound by the channel complex or one of its constituent parts compared to control animals." ; oboInOwl:hasNarrowSynonym "ligand gated channel activity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001783" ; a owl:Class ; rdfs:label "ligand gated channel activity variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0000656, obo:WBPhenotype_0001833 . obo:WBPhenotype_0001784 obo:IAO_0000115 "OBSOLETE: Animals are deficient in the formation or disassembly of lysosomes." ; obo:IAO_0100001 obo:WBPhenotype_0002562 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001784" ; a owl:Class ; rdfs:label "obsolete lysosome homeostasis deficient" ; owl:deprecated true . obo:WBPhenotype_0001785 obo:IAO_0000115 "Animals are deficient in their recalled and repeated responses to stimuli they are exposed to during learning and memory paradigms." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001785" ; a owl:Class ; rdfs:label "associative memory defective" ; rdfs:subClassOf obo:WBPhenotype_0002564 . obo:WBPhenotype_0001786 obo:IAO_0000115 "Animals exhibit variations in the targeting, clustering and or maintenance of ion channels in distinct subcellular domains of the neuron compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001786" ; a owl:Class ; rdfs:label "neuronal ion channel clustering defective" ; rdfs:subClassOf obo:WBPhenotype_0002563, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045161 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045161 ] ) ] ] . obo:WBPhenotype_0001787 obo:IAO_0000115 "Animals do not respond via directed movement to light stimuli in the same manner as control animals. In C. elegans, animals move away from light." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001787" ; a owl:Class ; rdfs:label "phototaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001897, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042331 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0042331 ] ) ] ] . obo:WBPhenotype_0001788 obo:IAO_0000115 "Animals survive longer than control animals after or during exposure to DNA damaging agents." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001788" ; a owl:Class ; rdfs:label "resistant to mutagens" ; rdfs:subClassOf obo:WBPhenotype_0000739, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25435 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25435 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001789 obo:IAO_0000115 "Life span of the animal is not influenced by changes in temperature in the same manner as control animals." ; oboInOwl:hasNarrowSynonym "temperature independent life span", "temperature influenced life span abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001789" ; a owl:Class ; rdfs:label "temperature influenced life span variant" ; rdfs:subClassOf obo:WBPhenotype_0000039, obo:WBPhenotype_0000146 . obo:WBPhenotype_0001790 obo:IAO_0000115 "Cooling or warming evoked changes in membrane currents are not observed." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ThRC absent" ; oboInOwl:id "WBPhenotype:0001790" ; a owl:Class ; rdfs:label "thermoreceptor currents absent" ; rdfs:subClassOf obo:WBPhenotype_0002563 . obo:WBPhenotype_0001791 obo:IAO_0000115 "Animals exhibit variations in temperature dependent differences in the length of their defecation cycle. In C. elegans the length of the cycle is the same at different temperatures, showing temperature compensation." ; oboInOwl:hasNarrowSynonym "defecation cycle temperature compensation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001791" ; a owl:Class ; rdfs:label "defecation cycle temperature compensation variant" ; rdfs:subClassOf obo:WBPhenotype_0000207 . obo:WBPhenotype_0001792 obo:IAO_0000115 "Nuclei of specific cells are smaller compared to control animals." ; oboInOwl:hasExactSynonym "nuclear size decreased" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001792" ; a owl:Class ; rdfs:label "nuclei small" ; rdfs:subClassOf obo:WBPhenotype_0002607, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005634 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001793 obo:IAO_0000115 "The anterior body contraction and expulsion steps of the defecation cycle are absent; posterior body contractions are still present." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Aex" ; oboInOwl:id "WBPhenotype:0001793" ; a owl:Class ; rdfs:label "aboc expulsion missing" ; rdfs:subClassOf obo:WBPhenotype_0000391 . obo:WBPhenotype_0001794 obo:IAO_0000115 "Discrete foci within the cytoplasm containing congregations of mRNA translational suppression and degradation mechanisms vary in their arrangement, clustering or are otherwise not well-defined compared to control." ; oboInOwl:hasNarrowSynonym "cytoplasmic processing body abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "P body abnormal" ; oboInOwl:id "WBPhenotype:0001794" ; a owl:Class ; rdfs:label "cytoplasmic processing body variant" ; rdfs:subClassOf obo:WBPhenotype_0001300, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000932 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000932 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001795 obo:IAO_0000115 "Animals exhibit variations in repeat lengths of microsatellite genomic sequences compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001795" ; a owl:Class ; rdfs:label "microsatellite instability" ; rdfs:subClassOf obo:WBPhenotype_0000000 . obo:WBPhenotype_0001796 obo:IAO_0000115 "Animals exhibit increased sensitivity to interstrand cross-linking agents, such as HN2 (nitrogen mustard) and CDDP (cisplatin) compared to control. In C. elegans, increased sensitivity to these agents is often observed as a decrease in survival compared to control animals after exposure to the agent." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "interstrand cross link agent hypersensitive" ; oboInOwl:id "WBPhenotype:0001796" ; a owl:Class ; rdfs:label "organism hypersensitive interstrand cross link agents" ; rdfs:subClassOf obo:WBPhenotype_0000067 . obo:WBPhenotype_0001797 obo:IAO_0000115 "Germline nuclei do not progress through pachytene to diplotene." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001797" ; a owl:Class ; rdfs:label "pachytene arrested germline nuclei" ; rdfs:subClassOf obo:WBPhenotype_0001946 . obo:WBPhenotype_0001798 obo:IAO_0000115 "The processes that inhibit the location or frequency of formation of synapses are downregulated resulting in the formation of synapses or synapse-like structures in areas of the neuron that are typically devoid of synapses in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001798" ; a owl:Class ; rdfs:label "inhibition of synaptogenesis defective" ; rdfs:subClassOf obo:WBPhenotype_0000625, obo:WBPhenotype_0000944, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051964 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051964 ] ) ] ] . obo:WBPhenotype_0001799 obo:IAO_0000115 "The processes that inhibit the location or frequency of formation of synapses are upregulated compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001799" ; a owl:Class ; rdfs:label "inhibition of synaptogenesis hyperactive" ; rdfs:subClassOf obo:WBPhenotype_0000944, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051964 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0002051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0051964 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001800 obo:IAO_0000115 "Changes in the levels of innate immune gene products in response to pathogen exposure are significantly different from that observed in control animals." ; oboInOwl:hasNarrowSynonym "antimicrobial gene expression abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001800" ; a owl:Class ; rdfs:label "pathogen induced antimicrobial gene expression variant" ; rdfs:subClassOf obo:WBPhenotype_0001857, obo:WBPhenotype_0002164, obo:WBPhenotype_0002534 . obo:WBPhenotype_0001801 obo:IAO_0000115 "Animals fail to establish or maintain characteristics that delineate the dendrite from the axon. The exclusion of presynaptic components from the dendrite is one indication of axodendritic polarity." ; oboInOwl:hasNarrowSynonym "axodendritic polarity abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001801" ; a owl:Class ; rdfs:label "axodendritic polarity variant" ; rdfs:subClassOf obo:WBPhenotype_0000944 . obo:WBPhenotype_0001802 obo:IAO_0000115 "Animals fail to relax their body wall muscles to the same extent as muscles in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001802" ; a owl:Class ; rdfs:label "body wall muscle relaxation defective" ; rdfs:subClassOf obo:WBPhenotype_0000596 . obo:WBPhenotype_0001803 obo:IAO_0000115 "Animals exhibit variations in the formation or disassembly of membrane bound organelles that traffic material between the plasma membrane and internal compartments of the cell, compared to control." ; oboInOwl:hasNarrowSynonym "endosome biogenesis abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001803" ; a owl:Class ; rdfs:label "endosome biogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001344 . obo:WBPhenotype_0001804 obo:IAO_0000115 "Animals exhibit a decrease in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by decreases in the number of Nile Red or BODIPY 493/503 staining bodies." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lipid body number reduced" ; oboInOwl:id "WBPhenotype:0001804" ; a owl:Class ; rdfs:label "fat associated bodies reduced" ; rdfs:subClassOf obo:WBPhenotype_0001901 . obo:WBPhenotype_0001805 obo:IAO_0000115 "Inner membrane of mitochondria are disconnected and form vesicular bodies." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001805" ; a owl:Class ; rdfs:label "mitochondria vesiculated" ; rdfs:subClassOf obo:WBPhenotype_0001401 . obo:WBPhenotype_0001806 obo:IAO_0000115 "Any variation in the ability of a protein to resist disintegration via chemical or physical modifications compared to control." ; oboInOwl:hasNarrowSynonym "protein stabilization abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001806" ; a owl:Class ; rdfs:label "protein stabilization variant" ; rdfs:subClassOf obo:WBPhenotype_0001644, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050821 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0050821 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001807 obo:IAO_0000115 "Any variation in the process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition compared to control." ; oboInOwl:hasNarrowSynonym "alternative splicing abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001807" ; a owl:Class ; rdfs:label "alternative splicing variant" ; rdfs:subClassOf obo:WBPhenotype_0000028 . obo:WBPhenotype_0001808 obo:IAO_0000115 "The degradation of genomic and or cellular material of the corpse does not occur at the same rate or under the same conditions as observed in control animals undergoing cell death." ; oboInOwl:hasNarrowSynonym "cell corpse digestion abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001808" ; a owl:Class ; rdfs:label "cell corpse digestion variant" ; rdfs:subClassOf obo:WBPhenotype_0000885 . obo:WBPhenotype_0001809 obo:IAO_0000115 "The formation of mature intracellular compartments via membrane fusion is disrupted." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001809" ; a owl:Class ; rdfs:label "organelle fusion defective" ; rdfs:subClassOf obo:WBPhenotype_0001344, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048284 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0048284 ] ) ] ] . obo:WBPhenotype_0001810 obo:IAO_0000115 "Animals exhibit variations in the partitioning of oocytes from each other compared to control animals." ; oboInOwl:hasNarrowSynonym "oocyte septum formation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "oocyte cellularization defective", "oocyte partition variant" ; oboInOwl:id "WBPhenotype:0001810" ; a owl:Class ; rdfs:label "oocyte septum formation variant" ; rdfs:subClassOf obo:WBPhenotype_0000399 . obo:WBPhenotype_0001811 obo:IAO_0000115 "Animals retain a significantly greater proportion of their fat upon serotonin treatment, compared to control." ; oboInOwl:hasNarrowSynonym "serotonin induced fat reduction abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "serotonin induced fat regulation" ; oboInOwl:id "WBPhenotype:0001811" ; a owl:Class ; rdfs:label "serotonin induced fat reduction variant" ; rdfs:subClassOf obo:WBPhenotype_0000024, obo:WBPhenotype_0001232 . obo:WBPhenotype_0001812 obo:IAO_0000115 "During development of the embryo, the epidermis loses integrity and the contents of the embryo are expelled." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001812" ; a owl:Class ; rdfs:label "embryonic rupture" ; rdfs:subClassOf obo:WBPhenotype_0000749 . obo:WBPhenotype_0001813 obo:IAO_0000115 "Animals exhibit defects in the stabilization of homologue pairing, which occurs through the initiation and formation of the synaptonemal complex, during meiosis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001813" ; a owl:Class ; rdfs:label "synapsis defective" ; rdfs:subClassOf obo:WBPhenotype_0002012, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007129 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0007129 ] ) ] ] . obo:WBPhenotype_0001814 obo:IAO_0000115 "Animals exhibit defects in the number or extent of connections between chromatids that occur during the process of genetic material exchange between homologous segments of non-sister chromatids." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "chiasma defective", "homologous recombination foci variant" ; oboInOwl:id "WBPhenotype:0001814" ; a owl:Class ; rdfs:label "crossover defective" ; rdfs:subClassOf obo:WBPhenotype_0002012, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005712 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001511 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005712 ] ) ] ] . obo:WBPhenotype_0001815 obo:IAO_0000115 "Animals exhibit defects in the asymmetric diassembly of the synaptonemal complex during progression through meiosis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001815" ; a owl:Class ; rdfs:label "desynapsis defective" ; rdfs:subClassOf obo:WBPhenotype_0002012 . obo:WBPhenotype_0001816 obo:IAO_0000115 "Neuromuscular signaling between neurons and egg laying musculature varies from that observed for control animals." ; oboInOwl:hasNarrowSynonym "egg laying circuit abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001816" ; a owl:Class ; rdfs:label "egg laying circuit variant" ; rdfs:subClassOf obo:WBPhenotype_0000929 . obo:WBPhenotype_0001817 obo:IAO_0000115 "The conditioned aversion to a specific chemical compound as a result of that compound being coupled with an unfavorable condition, such as starvation, does not increase to the same extent as observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "enhanced gustatory plasticity defective", "enhanced taste aversion defective", "starvation enhanced taste aversion defective" ; oboInOwl:id "WBPhenotype:0001817" ; a owl:Class ; rdfs:label "enhanced taste aversion defective" ; rdfs:subClassOf obo:WBPhenotype_0000147, obo:WBPhenotype_0001444 . obo:WBPhenotype_0001818 obo:IAO_0000115 "Activity of the neuron varies from that observed for control animals or neurons. In C. elegans neuron activity is often assayed by observing calcium spikes." ; oboInOwl:hasNarrowSynonym "neuron activation abnormal" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "neuron activity abnormal" ; oboInOwl:id "WBPhenotype:0001818" ; a owl:Class ; rdfs:label "neuron activation variant" ; rdfs:subClassOf obo:WBPhenotype_0002563 . obo:WBPhenotype_0001819 obo:IAO_0000115 "The number of pathogens associated with the animal vary from that associated with control animals." ; oboInOwl:hasNarrowSynonym "bacterial load variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001819" ; a owl:Class ; rdfs:label "pathogen load variant" ; rdfs:subClassOf obo:WBPhenotype_0001012 . obo:WBPhenotype_0001820 obo:IAO_0000115 "Animals tend to accumulate at the thickest part of the bacterial lawn." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "bordering increased" ; oboInOwl:id "WBPhenotype:0001820" ; a owl:Class ; rdfs:label "bordering" ; rdfs:subClassOf obo:WBPhenotype_0000662, obo:WBPhenotype_0001291 . obo:WBPhenotype_0001821 obo:IAO_0000115 "Animals do not accumulate at the thickest part of the bacterial lawn. Animals do not preferentially deplete bacterial food at the thicker parts of the lawn." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001821" ; a owl:Class ; rdfs:label "non bordering" ; rdfs:subClassOf obo:WBPhenotype_0000662, obo:WBPhenotype_0001291 . obo:WBPhenotype_0001822 obo:IAO_0000115 "Animals produce pheromone but it does not undergo controlled release into the environment." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001822" ; a owl:Class ; rdfs:label "dauer pheromone secretion variant" ; rdfs:subClassOf obo:WBPhenotype_0000258, obo:WBPhenotype_0000609 . obo:WBPhenotype_0001823 obo:IAO_0000115 "Any variation in the mechanism by which sperm find their correct target destinations (spermatheca)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001823" ; a owl:Class ; rdfs:label "sperm recruitment variant" ; rdfs:subClassOf obo:WBPhenotype_0001424 . obo:WBPhenotype_0001824 obo:IAO_0000115 "Animals exhibit variations in any process necessary for the progression through prophase during meiosis compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001824" ; a owl:Class ; rdfs:label "meiotic progression prophase variant" ; rdfs:subClassOf obo:WBPhenotype_0000313, obo:WBPhenotype_0000775 . obo:WBPhenotype_0001825 obo:IAO_0000115 "Animals have very few or no germline nuclei and gonad arms that are very small or missing." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001825" ; a owl:Class ; rdfs:label "rudimentary gonad" ; rdfs:subClassOf obo:WBPhenotype_0001355 . obo:WBPhenotype_0001826 obo:IAO_0000115 "Variations in the regulated breakdown of RNA species via the action of cellular enzymes (RNases) compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001826" ; a owl:Class ; rdfs:label "RNA degradation variant" ; rdfs:subClassOf obo:WBPhenotype_0000028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006401 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0006401 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001827 obo:IAO_0000115 "Variations in any process that involves the maintenance, biosynthesis or accumulation of RNA in the organism compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001827" ; a owl:Class ; rdfs:label "RNA metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000463, obo:WBPhenotype_0000585, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016070 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016070 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001828 obo:IAO_0000115 "Variations in the persistence of an RNAi induced phenotype compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001828" ; a owl:Class ; rdfs:label "RNAi persistence variant" ; rdfs:subClassOf obo:WBPhenotype_0000743, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000082 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016246 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000082 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0016246 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001829 obo:IAO_0000115 "Any variation that results in the premature differentiation of spermatids into motile spermatozoa compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001829" ; a owl:Class ; rdfs:label "premature spermatid activation" ; rdfs:subClassOf obo:WBPhenotype_0000670 . obo:WBPhenotype_0001830 obo:IAO_0000115 "Any variation in an animal's response to exposure to multiple stressors occuring simultaneously or during an overlapping temporal window compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001830" ; a owl:Class ; rdfs:label "response to multiple stressors variant" ; rdfs:subClassOf obo:WBPhenotype_0000738 . obo:WBPhenotype_0001831 obo:IAO_0000115 "Any variation in the formation of intestinal microvilli. Microvilli are actin-based cellular structures that form plasma membrane projections into the extracellular space and whose specialized shape provides increased cellular surface area. Microvilli are a crucial component of the terminal differentiation process for many epithelial cell types, usually ones that play an absorptive or filtering role." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001831" ; a owl:Class ; rdfs:label "intestinal microvilli variant" ; rdfs:subClassOf obo:WBPhenotype_0000705 . obo:WBPhenotype_0001832 obo:IAO_0000115 "Any variation that disrupts the assembly, distribution, localization or organization of any of the numerous similar discrete openings in the nuclear envelope, where the inner and outer nuclear membranes are joined." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001832" ; a owl:Class ; rdfs:label "nuclear pore variant" ; rdfs:subClassOf obo:WBPhenotype_0002037, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0005643 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000001 [ a owl:Restriction ; owl:onProperty obo:RO_0002314 ; owl:someValuesFrom obo:GO_0005643 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001833 obo:IAO_0000115 "Any variation in the directed movement of substances in a cell, from one side of a membrane to another, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "membrane transport variant", "transporter activity variant" ; oboInOwl:id "WBPhenotype:0001833" ; a owl:Class ; rdfs:label "membrane trafficking variant" ; rdfs:subClassOf obo:WBPhenotype_0000536 . obo:WBPhenotype_0001834 obo:IAO_0000115 "Variations in the processes regulating the excision of intervening introns from the primary mRNA transcript, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001834" ; a owl:Class ; rdfs:label "mRNA splicing variant" ; rdfs:subClassOf obo:WBPhenotype_0000028, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000398 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0000398 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001835 obo:IAO_0000115 "Variations in the amount of energy consumed by an organism compared to control. Energy expenditure is often determined by assaying oxygen consumption." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001835" ; a owl:Class ; rdfs:label "energy expenditure variant" ; rdfs:subClassOf obo:WBPhenotype_0000027 . obo:WBPhenotype_0001836 obo:IAO_0000115 "Any variation in the overall structure or appearance of the protective barrier which isolates the embryo from the external environment, compared to control ." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001836" ; a owl:Class ; rdfs:label "eggshell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000037, obo:WBPhenotype_0002558, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005843 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005843 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001837 obo:IAO_0000115 "Life span of the animal is not influenced by changes in diet in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001837" ; a owl:Class ; rdfs:label "diet induced life span variant" ; rdfs:subClassOf obo:WBPhenotype_0000039, obo:WBPhenotype_0002525 . obo:WBPhenotype_0001838 obo:IAO_0000115 "Gene expression of an animal is not influenced by drug treatment in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001838" ; a owl:Class ; rdfs:label "drug induced gene expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000717 . obo:WBPhenotype_0001839 obo:IAO_0000115 "Animals fail to respond to the concentration of phorbol esters that elicit a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. Phorbol esters such as PMA act as DAG mimetics." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001839" ; a owl:Class ; rdfs:label "phorbol ester resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_37532 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_37532 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001840 obo:IAO_0000115 "Variations in the processes that restore integrity to a damaged tissue following an injury, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "wound healing variant" ; oboInOwl:id "WBPhenotype:0001840" ; a owl:Class ; rdfs:label "response to injury variant" ; rdfs:subClassOf obo:WBPhenotype_0000142, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009611 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009611 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001841 obo:IAO_0000115 "Any variation in a series of molecular signals that help relay a receptor mediated signal within the cell, compared to control. Second messengers often comprise of ions (eg: Ca2+) or small molecules (cGMP, cAMP etc) that are formed or released into the cytosol." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001841" ; a owl:Class ; rdfs:label "second messenger mediated signaling variant" ; rdfs:subClassOf obo:WBPhenotype_0000463 . obo:WBPhenotype_0001842 obo:IAO_0000115 "Any variation in the state or activity of an organism as a result of abrupt discontinuation or decreased dosage of a drug, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "rebound response defective" ; oboInOwl:id "WBPhenotype:0001842" ; a owl:Class ; rdfs:label "drug withdrawal response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0001843 obo:IAO_0000115 "Animals exhibit variations in any process that involves the degradation, biosynthesis or accumulation of hormones within the organism compared to control. Hormones are naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001843" ; a owl:Class ; rdfs:label "hormone metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000027 . obo:WBPhenotype_0001844 obo:IAO_0000115 "Variations in the process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "fat granule regulated breakdown variant", "fat granule regulated hydrolysis variant", "lipid lysis regulation variant", "regulation of lipid catabolic process variant" ; oboInOwl:id "WBPhenotype:0001844" ; a owl:Class ; rdfs:label "lipid hydrolysis regulation variant" ; rdfs:subClassOf obo:WBPhenotype_0000725 . obo:WBPhenotype_0001845 obo:IAO_0000115 "Variations in the covalent alteration of one or more components (eg: fatty acids, sterols etc.) in a lipid, resulting in a change in the properties of the lipid, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001845" ; a owl:Class ; rdfs:label "lipid modification variant" ; rdfs:subClassOf obo:WBPhenotype_0000725 . obo:WBPhenotype_0001846 obo:IAO_0000115 "Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001846" ; a owl:Class ; rdfs:label "phagosome maturation defective" ; rdfs:subClassOf obo:WBPhenotype_0000885 . obo:WBPhenotype_0001847 obo:IAO_0000115 "Variations in the processes that facilitate/permit dauer entry when exposed to specific sterol molecules, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001847" ; a owl:Class ; rdfs:label "sterol induced dauer formation variant" ; rdfs:subClassOf obo:WBPhenotype_0001539 . obo:WBPhenotype_0001848 obo:IAO_0000115 "Variations in the process by which the anatomical structures of a tube are generated and organized, compared to control. Morphogenesis pertains to the creation of form or shape." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "tubulogenesis variant" ; oboInOwl:id "WBPhenotype:0001848" ; a owl:Class ; rdfs:label "tube morphogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000530 . obo:WBPhenotype_0001849 obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of zinc ions within an organism compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001849" ; a owl:Class ; rdfs:label "zinc homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0002029 . obo:WBPhenotype_0001850 obo:IAO_0000115 "Programmed cell death of germ cells caused by exposure to ionizing energy does not occur to the same extent as it does in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001850" ; a owl:Class ; rdfs:label "radiation induced germ cell apoptosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000737, obo:WBPhenotype_0002152 . obo:WBPhenotype_0001851 obo:IAO_0000115 "Animals exhibit variations in radiation induced non-apoptotic death of multipotential precursor cells or tissues (clonogens) compared to control. Elimination of clonogens results in normal tissue damage as well as solid-tumor eradication." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001851" ; a owl:Class ; rdfs:label "radiation induced reproductive cell death variant" ; rdfs:subClassOf obo:WBPhenotype_0001173, obo:WBPhenotype_0001268 . obo:WBPhenotype_0001852 obo:IAO_0000115 "Animals exhibit variations in their response to an agent that destroys or causes the expulsion of parasitic intestinal worms compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001852" ; a owl:Class ; rdfs:label "antihelmintic response variant" ; rdfs:subClassOf obo:WBPhenotype_0000459 . obo:WBPhenotype_0001853 obo:IAO_0000115 "Animals exhibit variations in their response to the amino-acetonitrile derivatives (AADs) class of synthetic anthelmintics, compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001853" ; a owl:Class ; rdfs:label "AAD response variant" ; rdfs:subClassOf obo:WBPhenotype_0001852 . obo:WBPhenotype_0001854 obo:IAO_0000115 "Animals exhibit variations in their response to the microtubule-depolymerizing drug benomyl, compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001854" ; a owl:Class ; rdfs:label "benomyl response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1901561 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1901561 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001855 obo:IAO_0000115 "Animals fail to respond to the concentration of fluoride ions that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to fluoride ions to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001855" ; a owl:Class ; rdfs:label "fluoride resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_17051 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_17051 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001856 obo:IAO_0000115 "Animals exhibit variations in their response to ivermectin, an agonist of glutamate-gated chloride channels, compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001856" ; a owl:Class ; rdfs:label "ivermectin response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0001852 . obo:WBPhenotype_0001857 obo:IAO_0000115 "Gene expression of an animal is not influenced by the exposure to disease causing agents in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001857" ; a owl:Class ; rdfs:label "pathogen induced gene expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000717, obo:WBPhenotype_0001012 . obo:WBPhenotype_0001858 obo:IAO_0000115 "Animals fail to suppress head oscillations in response to anterior touch. In C. elegans, this behavior is a result of tyraminergic signaling." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Sho" ; oboInOwl:id "WBPhenotype:0001858" ; a owl:Class ; rdfs:label "suppression of head oscillations defective" ; rdfs:subClassOf obo:WBPhenotype_0000595 . obo:WBPhenotype_0001859 obo:IAO_0000115 "Any variation in the aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "DCC localization variant" ; oboInOwl:id "WBPhenotype:0001859" ; a owl:Class ; rdfs:comment "Possible xp." ; rdfs:label "Dosage compensation complex assembly variant" ; rdfs:subClassOf obo:WBPhenotype_0000718 . obo:WBPhenotype_0001860 obo:IAO_0000115 "Variations in the directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001860" ; a owl:Class ; rdfs:label "endocytic recycling defective" ; rdfs:subClassOf obo:WBPhenotype_0001422 . obo:WBPhenotype_0001861 obo:IAO_0000115 "Gene expression of an animal is not influenced by environmental changes in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001861" ; a owl:Class ; rdfs:label "environmental stimuli induced gene expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000717 . obo:WBPhenotype_0001862 obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of manganese ions within an organism compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001862" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "manganese homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0002029 . obo:WBPhenotype_0001863 obo:IAO_0000115 "Animals exhibit variations in their response to manganese compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001863" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "manganese response variant" ; rdfs:subClassOf obo:WBPhenotype_0000523, obo:WBPhenotype_0000591, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010042 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010042 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001864 obo:IAO_0000115 "Any variation in the processes that modulate the frequency, rate or extent of the directed movement of a protein into, out of, within or between cells by means of some external agent such as a transporter or pore compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001864" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "protein transport variant" ; rdfs:subClassOf obo:WBPhenotype_0001644, obo:WBPhenotype_0001833 . obo:WBPhenotype_0001865 obo:IAO_0000115 "Variations in the process by which one or more ubiquitin moieties are added to a protein, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "protein ubiquitylation variant" ; oboInOwl:id "WBPhenotype:0001865" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "protein ubiquitination variant" ; rdfs:subClassOf obo:WBPhenotype_0001382 . obo:WBPhenotype_0001866 obo:IAO_0000115 "Animals exhibit a reduction in pathogen accumulation, persistent colonization, and luminal distension of the intestine." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Rpa" ; oboInOwl:id "WBPhenotype:0001866" ; a owl:Class ; rdfs:label "reduced pathogen accumulation" ; rdfs:subClassOf obo:WBPhenotype_0001819 . obo:WBPhenotype_0001867 obo:IAO_0000115 "Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubule spindle asters during a mitotic cell cycle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001867" ; a owl:Class ; rdfs:label "mitotic spindle asters defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001102, obo:WBPhenotype_0001110 . obo:WBPhenotype_0001868 obo:IAO_0000115 "Cells undergoing meiosis exhibit defects in the overall function or activity of the meiotic spindle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001868" ; a owl:Class ; rdfs:label "meiotic spindle defective" ; rdfs:subClassOf obo:WBPhenotype_0000775, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001624 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0072687 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001624 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0072687 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001869 obo:IAO_0000115 "Cells undergoing meiosis exhibit defects in the positioning of the meiotic spindle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001869" ; a owl:Class ; rdfs:label "meiotic spindle positioning defective" ; rdfs:subClassOf obo:WBPhenotype_0001868 . obo:WBPhenotype_0001870 obo:IAO_0000115 "Cells undergoing meiosis exhibit defects in the rotation of the meiotic spindle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001870" ; a owl:Class ; rdfs:label "meiotic spindle rotation defective" ; rdfs:subClassOf obo:WBPhenotype_0001868 . obo:WBPhenotype_0001871 obo:IAO_0000115 "Life span of the animal is not influenced by drug exposure in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001871" ; a owl:Class ; rdfs:label "drug induced life span variant" ; rdfs:subClassOf obo:WBPhenotype_0000039, obo:WBPhenotype_0000631 . obo:WBPhenotype_0001872 obo:IAO_0000115 "Locomotion of the animal is not influenced by drug exposure in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001872" ; a owl:Class ; rdfs:label "drug induced locomotion variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0001873 obo:IAO_0000115 "Early embryos exhibit defects in the aggregation, arrangement and bonding together of a set of components to form the meiotic spindle, the array of microtubules and associated molecules that serves to move duplicated and/or homologous chromosomes apart." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001873" ; a owl:Class ; rdfs:label "meiotic spindle assembly defective" ; rdfs:subClassOf obo:WBPhenotype_0001868 . obo:WBPhenotype_0001874 obo:IAO_0000115 "Any variation in the conjugation of the ubiquitin-like protein Nedd8 to another protein compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001874" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "protein neddylation variant" ; rdfs:subClassOf obo:WBPhenotype_0001382 . obo:WBPhenotype_0001875 obo:IAO_0000115 "Chromosomal masses fail to fully separate and remained linked during anaphase." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "chromosome bridging", "lagging chromatin" ; oboInOwl:id "WBPhenotype:0001875" ; a owl:Class ; rdfs:label "anaphase bridging" ; rdfs:subClassOf obo:WBPhenotype_0001378 . obo:WBPhenotype_0001876 obo:IAO_0000115 "Any variation in the formation or disassembly of the cylindrical structures that are composed of groupings of microtubules found close to the nucleus (centrioles) compared to control. Centrioles are arranged perpendicularly and are surrounded by an amorphous mass of dense material (the pericentriolar material). The centrioles and the pericentriolar material constitute the compound structure known as the centrosome." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001876" ; a owl:Class ; rdfs:label "centriole biogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001903 . obo:WBPhenotype_0001877 obo:IAO_0000115 "Any variation in the structure, form or composition of the membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001877" ; a owl:Class ; rdfs:label "nuclear membrane morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002037, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031965 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0031965 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001878 obo:IAO_0000115 "Animals exhibit variations in the response to the addition of hydroxyurea compared to that observed in control animals. Hydroxyurea stops DNA from being replicated." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "HU response variant", "hydroxycarbamide response variant" ; oboInOwl:id "WBPhenotype:0001878" ; a owl:Class ; rdfs:label "hydroxyurea response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0072710 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0072710 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001879 obo:IAO_0000115 "Animals respond to hydroxyurea at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001879" ; a owl:Class ; rdfs:label "hydroxyurea hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001878, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_44423 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_44423 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001880 obo:IAO_0000115 "Any variation in the form, structure or composition of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001880" ; a owl:Class ; rdfs:label "endoplasmic reticulum morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005783 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005783 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001881 obo:IAO_0000115 "Any variation in the normally asymmetric distribution of the endoplasmic reticulum during cell divisions of the early embryo. The endoplasmic reticulum (ER) is an irregular network of membranes, that occurs in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001881" ; a owl:Class ; rdfs:label "endoplasmic reticulum symmetry variant early emb" ; rdfs:subClassOf obo:WBPhenotype_0001880 . obo:WBPhenotype_0001882 obo:IAO_0000115 "Any variation in the number of chromosomes in a cell compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001882" ; a owl:Class ; rdfs:label "aneuploidy" ; rdfs:subClassOf obo:WBPhenotype_0000773 . obo:WBPhenotype_0001885 obo:IAO_0000115 "Embryos exhibit defects in the formation of the groove in the cell surface near the old metaphase plate at the onset of cytokinesis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001885" ; a owl:Class ; rdfs:label "cleavage furrow initiation defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001129 . obo:WBPhenotype_0001886 obo:IAO_0000115 "Embryos exhibit defects in the maintenance or termination of the groove in the cell surface near the old metaphase plate during cytokinesis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001886" ; a owl:Class ; rdfs:label "cleavage furrow termination defective early emb" ; rdfs:subClassOf obo:WBPhenotype_0001129 . obo:WBPhenotype_0001887 obo:IAO_0000115 "Animals execute supernumerary cell divisions during the development of the lateral, alae-producing epithelial cells, resulting in a larger number of these cells than control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001887" ; a owl:Class ; rdfs:label "excess seam cells" ; rdfs:subClassOf obo:WBPhenotype_0002175, obo:WBPhenotype_0002569 . obo:WBPhenotype_0001888 obo:IAO_0000115 "Animals exhibit an increase in the number of fat containing organelles compared to control. In C. elegans this number can be assayed by increases in the number of BODIPY 493/503 staining." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lipid body number increased", "lipid droplet expansion" ; oboInOwl:id "WBPhenotype:0001888" ; a owl:Class ; rdfs:label "fat associated bodies increased" ; rdfs:subClassOf obo:WBPhenotype_0001901 . obo:WBPhenotype_0001889 obo:IAO_0000115 "Any variation in the form, structure or composition of the repeating units of a myofibrils in a muscle cell that are composed of an array of overlapping thick and thin filaments, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001889" ; a owl:Class ; rdfs:label "body wall muscle sarcomere morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000926 . obo:WBPhenotype_0001890 obo:IAO_0000115 "Any variation in the attachment plaque for thin filaments onto the cell membrane. The dense body in body wall muscles is especially large, indenting far into the cytoplasm to border each sarcomere, thus providing a long row of coherent attachment sites at regular intervals (WormAtlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001890" ; a owl:Class ; rdfs:label "body wall muscle dense body variant" ; rdfs:subClassOf obo:WBPhenotype_0001889 . obo:WBPhenotype_0001891 obo:IAO_0000115 "Animals exhibit variations in the form, structure or composition of a planar structure within the muscle sarcomere which lies midway within the thick filament (A) band, attaching to the plasma membrane at its base and running up towards the inward surface of the myofilament lattice, compared to control animals (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001891" ; a owl:Class ; rdfs:label "M line variant" ; rdfs:subClassOf obo:WBPhenotype_0001889 . obo:WBPhenotype_0001892 obo:IAO_0000115 "Any variation in the levels of the polymerized form of glucose throughout the body of the animal as compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001892" ; a owl:Class ; rdfs:label "glycogen levels variant" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_28087 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_28087 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001893 obo:IAO_0000115 "Any reduction in the membrane potential (voltage gradient) across the inner mitochondrial membrane compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001893" ; a owl:Class ; rdfs:label "mitochondrial membrane potential reduced" ; rdfs:subClassOf obo:WBPhenotype_0001282 . obo:WBPhenotype_0001894 obo:IAO_0000115 "Animals exhibit variations in the number of nuclei contained in a particular cell type compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001894" ; a owl:Class ; rdfs:label "nuclear number variant" ; rdfs:subClassOf obo:WBPhenotype_0000504 . obo:WBPhenotype_0001895 obo:IAO_0000115 "Parental chromosomes fail to undergo appropriate mixing upon pronuclear fusion resulting in a zygotic nucleus in which parental genomes remain segregated." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "pronuclear fusion defective" ; oboInOwl:id "WBPhenotype:0001895" ; a owl:Class ; rdfs:label "parental chromosome mixing defective" ; rdfs:subClassOf obo:WBPhenotype_0001138 . obo:WBPhenotype_0001896 obo:IAO_0000115 "Animals exhibit a decrease in the extent of activation of programmed cell death by exposure to the nucleic acid damaging agent, gamma irradiation, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001896" ; a owl:Class ; rdfs:label "gamma ray induced apoptosis decreased" ; rdfs:subClassOf obo:WBPhenotype_0000182, obo:WBPhenotype_0001326 . obo:WBPhenotype_0001897 obo:IAO_0000115 "Variations in the state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus (electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light) compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Lite" ; oboInOwl:id "WBPhenotype:0001897" ; a owl:Class ; rdfs:label "light response variant" ; rdfs:subClassOf obo:WBPhenotype_0000525, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009416 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0009416 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001898 obo:IAO_0000115 "Variations in the process by which sister chromatids, identical chromosomes resulting from DNA replication, are physically separated during the meiotic cell cycle, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001898" ; a owl:Class ; rdfs:label "meiotic sister chromatid segregation variant" ; rdfs:subClassOf obo:WBPhenotype_0001499 . obo:WBPhenotype_0001899 obo:IAO_0000115 "Animals exhibit variations in the amount of glutathione compared to control animals at a defined stage. Glutathione, the tripeptide glutamylcysteinylglycine, acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001899" ; a owl:Class ; rdfs:label "glutathione levels variant" ; rdfs:subClassOf obo:WBPhenotype_0000027, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_16856 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000070 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CHEBI_16856 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001900 obo:IAO_0000115 "Animals exhibit a decrease in the cellular levels of reduced glutathione (GSH), compared to control. Reduced levels of GSH may be an indication of susceptibility to oxidative stress." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "reduced levels of GSH" ; oboInOwl:id "WBPhenotype:0001900" ; a owl:Class ; rdfs:label "reduced levels of reduced glutathione" ; rdfs:subClassOf obo:WBPhenotype_0001899 . obo:WBPhenotype_0001901 obo:IAO_0000115 "Animals exhibit variations in the formation or disassembly of fat containing organelles compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lipid body variant" ; oboInOwl:id "WBPhenotype:0001901" ; a owl:Class ; rdfs:label "fat associated bodies variant" ; rdfs:subClassOf obo:WBPhenotype_0001344 . obo:WBPhenotype_0001902 obo:IAO_0000115 "Animals exhibit an increase in the size of fat containing organelles compared to control. In C. elegans this can be assayed by BODIPY 493/503 staining." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "lipid body size increased" ; oboInOwl:id "WBPhenotype:0001902" ; a owl:Class ; rdfs:label "fat associated body size increased" ; rdfs:subClassOf obo:WBPhenotype_0001901 . obo:WBPhenotype_0001903 obo:IAO_0000115 "Animals exhibit variations in the formation, maturation or disassembly of the centrosome (a subcellular body consisting of two centrioles embedded in a protein matrix). The centrosome serves as a microtubule organizing center as well as a regulator of cell-cycle progression." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001903" ; a owl:Class ; rdfs:label "centrosome biogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001344 . obo:WBPhenotype_0001904 obo:IAO_0000115 "Animals fail to exhibit toxicity to the concentration of manganese that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals. In C. elegans toxic responses to manganese include dopamine (DA) neuron neurodegeneration." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001904" ; a owl:Class ; rdfs:label "manganese toxicity resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0001863, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18291 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18291 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001905 obo:IAO_0000115 "Animals lay fewer total number of eggs over the lifetime of the animal." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001905" ; a owl:Class ; rdfs:label "fewer eggs laid" ; rdfs:subClassOf obo:WBPhenotype_0000640 . obo:WBPhenotype_0001906 obo:IAO_0000115 "During epidermal morphogenesis, hypodermal cells do not properly undergo the characteristic cell shape changes necessary for the embryo to elongate." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001906" ; a owl:Class ; rdfs:label "hypodermal cell elongation defective" ; rdfs:subClassOf obo:WBPhenotype_0002569 . obo:WBPhenotype_0001907 obo:IAO_0000115 "Animals exhibit defects in the generation of the dorsal epithelial sheet, which entails distinct cell shape changes and movements to affect the interdigitation of two rows of dorsal cells resulting in a single row of cells across the dorsal midline." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001907" ; a owl:Class ; rdfs:label "dorsal intercalation defective" ; rdfs:subClassOf obo:WBPhenotype_0002569 . obo:WBPhenotype_0001908 obo:IAO_0000115 "The animal displays defects in any step of the ventral enclosure process resulting an embryo that is not enclosed and or with interior cells protruding out of the embryo." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001908" ; a owl:Class ; rdfs:label "ventral closure defective" ; rdfs:subClassOf obo:WBPhenotype_0001566 . obo:WBPhenotype_0001909 obo:IAO_0000115 "OBSOLETE. Any variation in the prevention of mRNA translation that normally occurs in certain cells, compared to control." ; obo:IAO_0100001 obo:WBPhenotype_0002157 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001909" ; a owl:Class ; rdfs:label "obsolete translational repression variant" ; owl:deprecated true . obo:WBPhenotype_0001910 obo:IAO_0000115 "Animals exhibit variations in the assembly, arrangement, orientation, or disassembly of the kinetochore, a multisubunit protein complex on chromosomes where the spindle fibers attach during cell division to pull the chromosomes apart." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001910" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "kinetochore organization variant" ; rdfs:subClassOf obo:WBPhenotype_0001348 . obo:WBPhenotype_0001911 obo:IAO_0000115 "Animals do not regrow axons following axon loss or damage, to the same extent, or in the same manner as observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001911" ; a owl:Class ; rdfs:label "axon regeneration defective" ; rdfs:subClassOf obo:WBPhenotype_0000880 . obo:WBPhenotype_0001912 obo:IAO_0000115 "The number of coelomocytes are reduced compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001912" ; a owl:Class ; rdfs:label "fewer coelomocytes" ; rdfs:subClassOf obo:WBPhenotype_0000618, obo:WBPhenotype_0002174 . obo:WBPhenotype_0001913 obo:IAO_0000115 "The number of coelomocytes are increased compared to control animals. Coelomocytes are free-floating spherical cells lying in the pseudocoelomic cavity of animals that can endocytose many compounds." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001913" ; a owl:Class ; rdfs:label "excess coelomocytes" ; rdfs:subClassOf obo:WBPhenotype_0000618, obo:WBPhenotype_0002175 . obo:WBPhenotype_0001914 obo:IAO_0000115 "Animals contain fewer pharyngeal cells compared to control animals. In C. elegans, pharyngeal cells are derived from MS-blastomere." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001914" ; a owl:Class ; rdfs:label "fewer pharyngeal cells" ; rdfs:subClassOf obo:WBPhenotype_0000707, obo:WBPhenotype_0002174 . obo:WBPhenotype_0001915 obo:IAO_0000115 "Any variation that results in the cellular expression of an mRNA in cells/tissues, that is otherwise not observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001915" ; a owl:Class ; rdfs:label "mRNA expression ectopic" ; rdfs:subClassOf obo:WBPhenotype_0000114 . obo:WBPhenotype_0001916 obo:IAO_0000115 "Pathogens internally associated with the animal exhibit an increase in survival compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001916" ; a owl:Class ; rdfs:label "increased pathogen survival" ; rdfs:subClassOf obo:WBPhenotype_0001819 . obo:WBPhenotype_0001917 obo:IAO_0000115 "Variations in the processes that incorporate acetyl groups to one or more amino acids within a protein, compared to control. An acetyl group is CH3CO-." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001917" ; a owl:Class ; rdfs:label "protein acetylation variant" ; rdfs:subClassOf obo:WBPhenotype_0001382 . obo:WBPhenotype_0001918 obo:IAO_0000115 "Animals respond to a specific chemical at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001918" ; a owl:Class ; rdfs:label "chemical hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000523, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_24431 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_24431 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001919 obo:IAO_0000115 "Animals exhibit larger inclusions within the intestinal cytoplasm, including birefringent crystalline objects and other dark-staining endosomes. In C. elegans these contents typically include glycogen granules (polysaccharide storage), rhabditin (carbohydrate storage), yolk granules (lipid and protein), and concentrated waste products (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001919" ; a owl:Class ; rdfs:label "gut granules enlarged" ; rdfs:subClassOf obo:WBPhenotype_0002240 . obo:WBPhenotype_0001920 obo:IAO_0000115 "The growth of pharyngeal components occurs in a radial fashion around the longitudinal axis of the worm as demonstrated by bent radial contractile arrays within the pharyngeal muscle cells. The defect is more pronounced as development progresses resulting in a more obvious twisting phenotype. Depending on the allele, the twist can be right-handed or left-handed" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Twp", "pharynx twisted" ; oboInOwl:id "WBPhenotype:0001920" ; a owl:Class ; rdfs:label "twisted pharynx" ; rdfs:subClassOf obo:WBPhenotype_0000707 . obo:WBPhenotype_0001921 obo:IAO_0000115 "Any variation in the creation of double-strand breaks that occur during meiosis that may result in the initiation of meiotic recombination." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001921" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "meiotic DNA double strand break formation variant" ; rdfs:subClassOf obo:WBPhenotype_0000775 . obo:WBPhenotype_0001922 obo:IAO_0000115 "Any variation in the directed movement of organelles or molecules along microtubules in nerve cell axons." ; oboInOwl:hasExactSynonym "axon transport variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "axon cargo transport variant" ; oboInOwl:id "WBPhenotype:0001922" ; a owl:Class ; rdfs:comment "Possible XP." ; rdfs:label "axonal transport variant" ; rdfs:subClassOf obo:WBPhenotype_0002563 . obo:WBPhenotype_0001923 obo:IAO_0000115 "The population of the lateral, alae-producing epithelial cells (seam cells) is reduced compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001923" ; a owl:Class ; rdfs:label "fewer seam cells" ; rdfs:subClassOf obo:WBPhenotype_0002174, obo:WBPhenotype_0002569 . obo:WBPhenotype_0001924 obo:IAO_0000115 "Oocytes are found one on top of the other in the dorsal to ventral orientation in the gonad." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001924" ; a owl:Class ; rdfs:label "oocytes stacked" ; rdfs:subClassOf obo:WBPhenotype_0001260 . obo:WBPhenotype_0001925 obo:IAO_0000115 "Oocytes are no longer arranged in the gonad in the same manner as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001925" ; a owl:Class ; rdfs:label "oocytes disorganized" ; rdfs:subClassOf obo:WBPhenotype_0001260 . obo:WBPhenotype_0001926 obo:IAO_0000115 "Basal contraction rate and or peak contraction rate of the gonadal sheath is increased relative to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001926" ; a owl:Class ; rdfs:label "gonad sheath contraction rate increased" ; rdfs:subClassOf obo:WBPhenotype_0001199 . obo:WBPhenotype_0001927 obo:IAO_0000115 "Animals produce an excess number of distal tip cells compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001927" ; a owl:Class ; rdfs:label "extra distal tip cells" ; rdfs:subClassOf obo:WBPhenotype_0001656, obo:WBPhenotype_0002175 . obo:WBPhenotype_0001928 obo:IAO_0000115 "Animals produce an excess number of gonad arms compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001928" ; a owl:Class ; rdfs:label "extra gonad arms" ; rdfs:subClassOf obo:WBPhenotype_0000399 . obo:WBPhenotype_0001929 obo:IAO_0000115 "The gonads of male animals do not produce the linker cell involved in guiding the developing male gonad to the sex organs in the male tail." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001929" ; a owl:Class ; rdfs:label "linker cell absent" ; rdfs:subClassOf obo:WBPhenotype_0001675, obo:WBPhenotype_0002174, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005062 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005062 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001930 obo:IAO_0000115 "Animals extend altered or fewer numbers of dorsal and or ventral muscle arms compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Madd", "muscle arm extension defective" ; oboInOwl:id "WBPhenotype:0001930" ; a owl:Class ; rdfs:label "muscle arm development defective" ; rdfs:subClassOf obo:WBPhenotype_0000540 . obo:WBPhenotype_0001931 obo:IAO_0000115 "The morphology or number of connections between muscle arms and commissural motor axons varies from control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001931" ; a owl:Class ; rdfs:label "muscle arm axon connection variant" ; rdfs:subClassOf obo:WBPhenotype_0000540 . obo:WBPhenotype_0001932 obo:IAO_0000115 "Animals exhibit ectopic plasma membrane extensions from muscle, these extensions are random projections that are thinner than the typical muscle arm." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001932" ; a owl:Class ; rdfs:label "myopodia present" ; rdfs:subClassOf obo:WBPhenotype_0000904 . obo:WBPhenotype_0001933 obo:IAO_0000115 "The pattern of localization of presynaptic markers is disrupted compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Sam" ; oboInOwl:id "WBPhenotype:0001933" ; a owl:Class ; rdfs:label "synaptic vesicle tag abnormal in mechanosensory neurons" ; rdfs:subClassOf obo:WBPhenotype_0000847 . obo:WBPhenotype_0001934 obo:IAO_0000115 "Any variation in the extension of vulval muscles compared to control. In C. elegans contralateral vulval muscles fail to meet at the midline." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Vme" ; oboInOwl:id "WBPhenotype:0001934" ; a owl:Class ; rdfs:label "vulval muscle extension variant" ; rdfs:subClassOf obo:WBPhenotype_0001314 . obo:WBPhenotype_0001935 obo:IAO_0000115 "Animals become paralyzed in response to aggregation of proteins like poly-glutamine or beta-amyloid." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001935" ; a owl:Class ; rdfs:label "protein aggregation induced paralysis" ; rdfs:subClassOf obo:WBPhenotype_0002425 . obo:WBPhenotype_0001936 obo:IAO_0000115 "Animals fail to respond to the aggregation of proteins that elicits a paralysis response in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001936" ; a owl:Class ; rdfs:label "resistant to protein aggregation induced paralysis" ; rdfs:subClassOf obo:WBPhenotype_0001935 . obo:WBPhenotype_0001937 obo:IAO_0000115 "Animals respond to protein aggregation at a lower concentration of aggregates or in less time compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001937" ; a owl:Class ; rdfs:label "hypersensitive to protein aggregation induced paralysis" ; rdfs:subClassOf obo:WBPhenotype_0001935 . obo:WBPhenotype_0001938 obo:IAO_0000115 "Any variation in the process of restoring DNA after damage. DNA damage can be caused by a many chemical or physical agents, and this damage is repaired by a variety of different DNA repair pathways." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001938" ; a owl:Class ; rdfs:label "DNA repair variant" ; rdfs:subClassOf obo:WBPhenotype_0000732 . obo:WBPhenotype_0001939 obo:IAO_0000115 "Animals are not repelled by bitter tastants such as quinine, primaquine quinacrine etc., to the same extent as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001939" ; a owl:Class ; rdfs:label "bitter tastant response variant" ; rdfs:subClassOf obo:WBPhenotype_0001450 . obo:WBPhenotype_0001940 obo:IAO_0000115 "Any variation in the form, structure or composition of the nucleus-free core of germ line cytoplasm in the gonad compared to control animals. In the C. elegans germline, nuclei exiting mitosis and entering meiosis are arranged along the cortex of the germline, partially enclosed by cellular membrane, forming a nucleus-free core of germline cytoplasm, called the rachis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "rachis morphology abnormal" ; oboInOwl:id "WBPhenotype:0001940" ; a owl:Class ; rdfs:label "rachis morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001355 . obo:WBPhenotype_0001941 obo:IAO_0000115 "The nucleus-free core of germline cytoplasm in the gonad is not as wide as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001941" ; a owl:Class ; rdfs:label "rachis narrow" ; rdfs:subClassOf obo:WBPhenotype_0001940 . obo:WBPhenotype_0001942 obo:IAO_0000115 "The nucleus-free core of germline cytoplasm in the gonad is missing." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001942" ; a owl:Class ; rdfs:label "rachis absent" ; rdfs:subClassOf obo:WBPhenotype_0001940 . obo:WBPhenotype_0001943 obo:IAO_0000115 "The width of the nucleus-free core of germline cytoplasm in the gonad is larger compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001943" ; a owl:Class ; rdfs:label "rachis wide" ; rdfs:subClassOf obo:WBPhenotype_0001940 . obo:WBPhenotype_0001944 obo:IAO_0000115 "A decreased number of celullarized haploid female germ cells (oocytes) are present in the gonad compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "fewer oocytes" ; oboInOwl:id "WBPhenotype:0001944" ; a owl:Class ; rdfs:label "oocyte number decreased" ; rdfs:subClassOf obo:WBPhenotype_0000186, obo:WBPhenotype_0001260 . obo:WBPhenotype_0001945 obo:IAO_0000115 "The size of haploid female germ cells (oocytes) are significantly smaller compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001945" ; a owl:Class ; rdfs:label "oocytes small" ; rdfs:subClassOf obo:WBPhenotype_0001260, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006797 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0006797 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001946 obo:IAO_0000115 "Developing oocytes show defects in their entry, progression through or exit from the pachytene stage compared to control animals. Pachytene is a cell cycle process comprising the steps by which a cell progresses through the third stage of prophase I in meiosis, in which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001946" ; a owl:Class ; rdfs:label "pachytene progression during oogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001824 . obo:WBPhenotype_0001947 obo:IAO_0000115 "Developing oocytes show defects in their entry, progression through or exit from the diplotene stage compared to control animals. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001947" ; a owl:Class ; rdfs:label "diplotene progression during oogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001824 . obo:WBPhenotype_0001948 obo:IAO_0000115 "Developing oocytes show defects in their entry, progression through or exit from the diakinesis stage compared to control animals. Diakinesis is a cell cycle process comprising the steps by which a cell progresses through the final stage of prophase I in meiosis; the transition to meiotic metaphase I." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001948" ; a owl:Class ; rdfs:label "diakinesis progression during oogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0001824 . obo:WBPhenotype_0001949 obo:IAO_0000115 "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diakinesis stage. In C. elegans the diakinesis region occurs in the proximal gonad arm and is preceded by the diplotene region. In the diakinesis region oocytes arrest until oocyte maturation occurs." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001949" ; a owl:Class ; rdfs:label "diakinesis region organization variant" ; rdfs:subClassOf obo:WBPhenotype_0001355, obo:WBPhenotype_0001948 . obo:WBPhenotype_0001950 obo:IAO_0000115 "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the gonad that are in the diplotene stage. In C. elegans the diplotene region follows the pachytene region and occurs just distal to, and coincident with, the loop in the gonad arm. In the diplotene region germ cell compartments become organized into a single file." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001950" ; a owl:Class ; rdfs:label "diplotene region organization variant" ; rdfs:subClassOf obo:WBPhenotype_0001355, obo:WBPhenotype_0001947 . obo:WBPhenotype_0001951 obo:IAO_0000115 "Animals exhibit variations from control animals in the organization of the germ cell nuclei in the pachytene stage region of the gonad. In C. elegans the pachytene region begins just proximal to the germline's transition zone, where germ cells coordinately switch into the leptotene/zygotene stage from the premeiosis stage (WormAtlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001951" ; a owl:Class ; rdfs:label "pachytene region organization variant" ; rdfs:subClassOf obo:WBPhenotype_0001355, obo:WBPhenotype_0001946 . obo:WBPhenotype_0001952 obo:IAO_0000115 "Variations in the directed movement/or positioning of a nucleus to a specific location within the germline compartment compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "germline nuclear migration variant" ; oboInOwl:id "WBPhenotype:0001952" ; a owl:Class ; rdfs:label "germline nuclear positioning variant" ; rdfs:subClassOf obo:WBPhenotype_0000511 . obo:WBPhenotype_0001953 obo:IAO_0000115 "Nuclei have fallen out of developing germ cell compartments into the rachis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001953" ; a owl:Class ; rdfs:label "nuclear fallout" ; rdfs:subClassOf obo:WBPhenotype_0001952 . obo:WBPhenotype_0001954 obo:IAO_0000115 "The diplotene stage is not observed in developing oocytes. Diplotene is a cell cycle process comprising the steps by which a cell progresses through the fourth stage of prophase I in meiosis, in which the homologous chromosomes begin to separate and the synaptonemal complex dissolves." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001954" ; a owl:Class ; rdfs:label "diplotene absent during oogenesis" ; rdfs:subClassOf obo:WBPhenotype_0001947 . obo:WBPhenotype_0001955 obo:IAO_0000115 "Haploid female germ cells (oocytes) contain more than one nucleus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "multinucleate oocyte" ; oboInOwl:id "WBPhenotype:0001955" ; a owl:Class ; rdfs:label "multiple nuclei oocyte" ; rdfs:subClassOf obo:WBPhenotype_0000186, obo:WBPhenotype_0001260, obo:WBPhenotype_0002413 . obo:WBPhenotype_0001956 obo:IAO_0000115 "Haploid female germ cells (oocytes) lack a nucleus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "anucleate oocytes" ; oboInOwl:id "WBPhenotype:0001956" ; a owl:Class ; rdfs:label "oocytes lack nucleus" ; rdfs:subClassOf obo:WBPhenotype_0000186, obo:WBPhenotype_0001260 . obo:WBPhenotype_0001957 obo:IAO_0000115 "A decrease in size of the specialized tissue of the reproductive tract that produces the male or female gametes compared to control (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001957" ; a owl:Class ; rdfs:label "gonad small" ; rdfs:subClassOf obo:WBPhenotype_0001355, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005175 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000587 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005175 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001958 obo:IAO_0000115 "Animals contain a gonad that initially functioned, but subsequently stopped. In hermaphrodites or females there is often the presence old embryos and/or hatched larva, but no young embryos, in the uterus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "degenerate gonad" ; oboInOwl:id "WBPhenotype:0001958" ; a owl:Class ; rdfs:label "gonad degenerate" ; rdfs:subClassOf obo:WBPhenotype_0001355 . obo:WBPhenotype_0001959 obo:IAO_0000115 "Pulling forces on the astral microtubules at the spindle poles vary from that observed for control spindles." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001959" ; a owl:Class ; rdfs:label "spindle pole pulling force variant" ; rdfs:subClassOf obo:WBPhenotype_0002414 . obo:WBPhenotype_0001960 obo:IAO_0000115 "The spindle in the early embryo is aberrant in the characteristic posterior aster oscillations that occur along the transverse longitudinal axis of the spindle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001960" ; a owl:Class ; rdfs:label "spindle oscillation variant" ; rdfs:subClassOf obo:WBPhenotype_0002414 . obo:WBPhenotype_0001961 obo:IAO_0000115 "Animals continue to produce progeny significantly past the time reproduction stops in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001961" ; a owl:Class ; rdfs:label "reproductive longevity extended" ; rdfs:subClassOf obo:WBPhenotype_0001739 . obo:WBPhenotype_0001962 obo:IAO_0000115 "Animals produce less distal tip cells compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001962" ; a owl:Class ; rdfs:label "missing distal tip cells" ; rdfs:subClassOf obo:WBPhenotype_0001656, obo:WBPhenotype_0002174 . obo:WBPhenotype_0001963 obo:IAO_0000115 "The association of homologs during diakinesis and the maintenance of their association through meiosis I as well as the preservation of centromeric cohesin between sister chromatids does not proceed as it does in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001963" ; a owl:Class ; rdfs:label "homolog association variant" ; rdfs:subClassOf obo:WBPhenotype_0001824 . obo:WBPhenotype_0001964 obo:IAO_0000115 "Animals exhibit differential regulation of the dopaminergic fate among the various classes of dopaminergic neurons." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "Dopy" ; oboInOwl:id "WBPhenotype:0001964" ; a owl:Class ; rdfs:label "dopaminergic fate atypical" ; rdfs:subClassOf obo:WBPhenotype_0001510 . obo:WBPhenotype_0001965 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of the cell, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001965" ; a owl:Class ; rdfs:label "cell membrane physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0000536 . obo:WBPhenotype_0001966 obo:IAO_0000115 "Animals exhibit variations in any physical or chemical process required for the composition, component distribution, or other aspect of membranes of within the cell, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001966" ; a owl:Class ; rdfs:label "cell endomembrane physiology variant" ; rdfs:subClassOf obo:WBPhenotype_0001965 . obo:WBPhenotype_0001967 obo:IAO_0000115 "Animals differ from control animals in the length of or mechanics of the steps that culminate in the preservation and subsequent disassembly of the synaptonemal complex, the specification of bivalent arms, and proper cohesion of sister chromatids." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001967" ; a owl:Class ; rdfs:label "meiotic chromatin reorganization variant" ; rdfs:subClassOf obo:WBPhenotype_0002012 . obo:WBPhenotype_0001968 obo:IAO_0000115 "All somatic gonad precursor (SGP) daughters adopt a proximal fate resulting in an increase in the number of AC precursor cells at the expense of distal tip cells (DTC), which are thereby absent." ; oboInOwl:hasBroadSynonym "Sys" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "symmetrical sisters" ; oboInOwl:id "WBPhenotype:0001968" ; a owl:Class ; rdfs:label "somatic gonad precursor symmetrical sisters" ; rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0001235 . obo:WBPhenotype_0001969 obo:IAO_0000115 "Any variation in the form or composition of the compartments in the germline of females/hermaphrodites compared to control animals. In C. elegans these compartments contain a nucleus and are connected to a common cytoplasm (rachis). These compartments eventually undergo cellularization and become oocytes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001969" ; a owl:Class ; rdfs:label "germ cell compartment morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000900 . obo:WBPhenotype_0001970 obo:IAO_0000115 "Germ cell compartments contain an an atypical number on nuclei compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001970" ; a owl:Class ; rdfs:label "germ cell compartment nuclei number variant" ; rdfs:subClassOf obo:WBPhenotype_0001969 . obo:WBPhenotype_0001971 obo:IAO_0000115 "Germ cell compartments do not contain a nucleus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001971" ; a owl:Class ; rdfs:label "germ cell compartment anucleate" ; rdfs:subClassOf obo:WBPhenotype_0001970 . obo:WBPhenotype_0001972 obo:IAO_0000115 "Germ cell compartments contain multiple nuclei." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001972" ; a owl:Class ; rdfs:label "germ cell compartment multinucleate" ; rdfs:subClassOf obo:WBPhenotype_0001970 . obo:WBPhenotype_0001973 obo:IAO_0000115 "Any variation in germ cell compartment size compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001973" ; a owl:Class ; rdfs:label "germ cell compartment size variant" ; rdfs:subClassOf obo:WBPhenotype_0001969 . obo:WBPhenotype_0001974 obo:IAO_0000115 "Germ cell compartments are smaller than that of control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001974" ; a owl:Class ; rdfs:label "germ cell compartment small" ; rdfs:subClassOf obo:WBPhenotype_0001973 . obo:WBPhenotype_0001975 obo:IAO_0000115 "Germ cell compartments are larger than that of control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001975" ; a owl:Class ; rdfs:label "germ cell compartment large" ; rdfs:subClassOf obo:WBPhenotype_0001973 . obo:WBPhenotype_0001976 obo:IAO_0000115 "OBSOLETE." ; obo:IAO_0100001 obo:WBPhenotype_0001978 ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001976" ; a owl:Class ; owl:deprecated true . obo:WBPhenotype_0001977 obo:IAO_0000115 "Any variation in the form or composition of the compartment partitions in the germline of females/hermaphrodites that exist when nuclei are still connected to a common cytoplasm (rachis), compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001977" ; a owl:Class ; rdfs:label "germ cell partition morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001969 . obo:WBPhenotype_0001978 obo:IAO_0000115 "Animals lack germ cell partitions (germ cell compartments)." ; oboInOwl:hasAlternativeId "WBPhenotype:0001976" ; oboInOwl:hasExactSynonym "germ cell compartment absent" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001978" ; a owl:Class ; rdfs:label "germ cell partition absent" ; rdfs:subClassOf obo:WBPhenotype_0001977 . obo:WBPhenotype_0001979 obo:IAO_0000115 "Animals contain small, fluid-filled, anucleate, spherical membrane-bound structures within the gonad." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001979" ; a owl:Class ; rdfs:label "gonad vesiculated" ; rdfs:subClassOf obo:WBPhenotype_0001355 . obo:WBPhenotype_0001980 obo:IAO_0000115 "Animals exhibit variations in the increase in size of compartments of the germline. In the C. elegans germline, syncytial compartments enlarge just prior to and coincident with the loop region, eventually abscising, to become fully enclosed germ cells (oocytes)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001980" ; a owl:Class ; rdfs:label "germ cell compartment expansion variant" ; rdfs:subClassOf obo:WBPhenotype_0001969 . obo:WBPhenotype_0001981 obo:IAO_0000115 "The compartments of the germline do not increase in size." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001981" ; a owl:Class ; rdfs:label "germ cell compartment expansion absent" ; rdfs:subClassOf obo:WBPhenotype_0001980 . obo:WBPhenotype_0001982 obo:IAO_0000115 "Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001982" ; a owl:Class ; rdfs:label "cell membrane organization biogenesis variant" ; rdfs:subClassOf obo:WBPhenotype_0010002 . obo:WBPhenotype_0001983 obo:IAO_0000115 "Variation of the time an individual spent on a patch of food (bacterial lawn) before leaving, compared to control animals." ; oboInOwl:hasExactSynonym "food leaving behavior variant", "patch leaving behavior variant" ; oboInOwl:hasNarrowSynonym "exploratory behavior variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "exploration behavior variant" ; oboInOwl:id "WBPhenotype:0001983" ; a owl:Class ; rdfs:label "lawn leaving behavior variant" ; rdfs:subClassOf obo:WBPhenotype_0000662 . obo:WBPhenotype_0001984 obo:IAO_0000115 "Animals exhibit axons with migration behaviors that differ from those observed in control animals after the axons cross a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001984" ; a owl:Class ; rdfs:label "long range axon migration variant" ; rdfs:subClassOf obo:WBPhenotype_0001224 . obo:WBPhenotype_0001985 obo:IAO_0000115 "Animals exhibit axons with migration behaviors that differ from those observed in control animals before the axons reach a half-way point between opposing neural cords. In C. elegans this point is marked by the lateral seam cells between the ventral and dorsal cords." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001985" ; a owl:Class ; rdfs:label "short range axon migration variant" ; rdfs:subClassOf obo:WBPhenotype_0001224 . obo:WBPhenotype_0001986 obo:IAO_0000115 "Animals undergo an irreversible high temperature-induced developmental arrest during the first larval stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001986" ; a owl:Class ; rdfs:label "high temperature induced L1 arrest" ; rdfs:subClassOf obo:WBPhenotype_0000081, obo:WBPhenotype_0001273 . obo:WBPhenotype_0001987 obo:IAO_0000115 "Any variation in the measured levels of acetylcholinesterase (AChE) activity compared to control animals." ; oboInOwl:hasExactSynonym "acetylcholinesterase class activity variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001987" ; a owl:Class ; rdfs:label "acetylcholinesterase activity variant" ; rdfs:subClassOf obo:WBPhenotype_0000124 . obo:WBPhenotype_0001988 obo:IAO_0000115 "Animals respond to a detergent at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001988" ; a owl:Class ; rdfs:label "detergent hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27780 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27780 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0001989 obo:IAO_0000115 "Animals respond to hypoxic (low oxygen levels) stress after a shorter exposure time compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001989" ; a owl:Class ; rdfs:label "hypoxia hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0002423 . obo:WBPhenotype_0001990 obo:IAO_0000115 "Animals fail to respond to low amounts of oxygen that elicit a response in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001990" ; a owl:Class ; rdfs:label "hypoxia resistant" ; rdfs:subClassOf obo:WBPhenotype_0002423 . obo:WBPhenotype_0001991 obo:IAO_0000115 "Response to low levels of oxygen is reduced or weakened compared to the response of control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001991" ; a owl:Class ; rdfs:label "hypoxia response attenuated" ; rdfs:subClassOf obo:WBPhenotype_0002423 . obo:WBPhenotype_0001992 obo:IAO_0000115 "Animals exhibit an increase in the number of somatic sheath cells surrounding each gonad arm compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001992" ; a owl:Class ; rdfs:label "extra gonadal sheath cells" ; rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0002175 . obo:WBPhenotype_0001993 obo:IAO_0000115 "Animals exhibit fewer somatic sheath cells surrounding each gonad arm, compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001993" ; a owl:Class ; rdfs:label "fewer gonadal sheath cells" ; rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0002174 . obo:WBPhenotype_0001994 obo:IAO_0000115 "Any variation in the establishment of left-right asymmetry of the body axis compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "left right asymmetry variant" ; oboInOwl:id "WBPhenotype:0001994" ; a owl:Class ; rdfs:label "left right handedness variant" ; rdfs:subClassOf obo:WBPhenotype_0000578 . obo:WBPhenotype_0001995 obo:IAO_0000115 "Cells of the animals exhibit variations in the progression or exit from the biochemical and morphological processes that occur during successive replication or nuclear replication events from that observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001995" ; a owl:Class ; rdfs:label "cell cycle progression variant" ; rdfs:subClassOf obo:WBPhenotype_0000740 . obo:WBPhenotype_0001996 obo:IAO_0000115 "Any variation in the cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence before entering the S phase, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001996" ; a owl:Class ; rdfs:label "cell cycle quiescence variant" ; rdfs:subClassOf obo:WBPhenotype_0001995 . obo:WBPhenotype_0001997 obo:IAO_0000115 "The nucleus or nuclei are not positioned in a similar manner or pattern in the cell or syncytium to that observed in controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001997" ; a owl:Class ; rdfs:label "nuclear anchoring variant" ; rdfs:subClassOf obo:WBPhenotype_0000511 . obo:WBPhenotype_0001998 obo:IAO_0000115 "Animals respond more severely to laser ablation than control animals subjected to the same laser ablation conditions." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001998" ; a owl:Class ; rdfs:label "hypersensitive to laser ablation" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0001999 obo:IAO_0000115 "Animals behave differently from control animals in assays testing for the ability to resolve or respond to conflicting sensory inputs." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0001999" ; a owl:Class ; rdfs:label "conflicting sensory integration variant" ; rdfs:subClassOf obo:WBPhenotype_0000738 . obo:WBPhenotype_0002000 obo:IAO_0000115 "Animals that exhibit an increase in locomotion activity do not return to basal level locomotion activity at the same rate as that of control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002000" ; a owl:Class ; rdfs:label "recovery from enhanced locomotion variant" ; rdfs:subClassOf obo:WBPhenotype_0000641 . obo:WBPhenotype_0002001 obo:IAO_0000115 "The number of synapses per unit area of a neuron differs in the animal compared to that observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002001" ; a owl:Class ; rdfs:label "synapse density variant" ; rdfs:subClassOf obo:WBPhenotype_0000604 . obo:WBPhenotype_0002002 obo:IAO_0000115 "A cell or cell of the animal exhibits extra centrosomes (a subcellular body consisting of two centrioles embedded in a protein matrix) compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002002" ; a owl:Class ; rdfs:label "supernumerary centrosomes" ; rdfs:subClassOf obo:WBPhenotype_0001903 . obo:WBPhenotype_0002003 obo:IAO_0000115 "Animals exhibit variations in steady-state levels of hydrogen peroxide (H2O2) compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002003" ; a owl:Class ; rdfs:label "hydrogen peroxide homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0002004 obo:IAO_0000115 "Animals exhibit defects in the flow rate or targeting of the cortical actomyosin network, which occurs during polarization as well as contraction of the contractile ring, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002004" ; a owl:Class ; rdfs:label "actomyosin contractility defective" ; rdfs:subClassOf obo:WBPhenotype_0000034, obo:WBPhenotype_0001587, obo:WBPhenotype_0002408 . obo:WBPhenotype_0002005 obo:IAO_0000115 "The tension of the cytoskeleton comprised of the actomyosin network differs from controls. This tension can be measured by laser-cutting of the actomyosin cytoskeleton and observing any differences the recoil velocity of cortex adjacent to the cut site." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002005" ; a owl:Class ; rdfs:label "actomyosin cytoskeletal tension variant" ; rdfs:subClassOf obo:WBPhenotype_0001346 . obo:WBPhenotype_0002006 obo:IAO_0000115 "Compared to controls, embryos exhibit variations in the part meiosis I in which homologous chromosomes separate and migrate away from each other." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002006" ; a owl:Class ; rdfs:label "anaphase I progression variant early embryo" ; rdfs:subClassOf obo:WBPhenotype_0000775, obo:WBPhenotype_0002389 . obo:WBPhenotype_0002007 obo:IAO_0000115 "Embryos display cortical protusions during cytokinesis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002007" ; a owl:Class ; rdfs:label "cortical blebs present" ; rdfs:subClassOf obo:WBPhenotype_0000764, obo:WBPhenotype_0002408 . obo:WBPhenotype_0002008 obo:IAO_0000115 "Animals exhibit variations in the non-enzymatic glycosylation process of attaching a protein or lipid to a sugar molecule, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002008" ; a owl:Class ; rdfs:label "glycation variant" ; rdfs:subClassOf obo:WBPhenotype_0000027 . obo:WBPhenotype_0002009 obo:IAO_0000115 "Animals exhibit variations from controls in their protein degradation machinery, which functions through the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002009" ; a owl:Class ; rdfs:label "proteasome core activity variant" ; rdfs:subClassOf obo:WBPhenotype_0001644 . obo:WBPhenotype_0002010 obo:IAO_0000115 "The dynamics of the replacement of old proteins by newly synthesized or modified proteins varies from that of control animals. This phenotype is often measured by fluorescence recovery after photobleaching (FRAP)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002010" ; a owl:Class ; rdfs:label "protein turnover variant" ; rdfs:subClassOf obo:WBPhenotype_0001644 . obo:WBPhenotype_0002011 obo:IAO_0000115 "Animals exhibit a secondary vulval invagination that is anterior or posterior to the primary opening depending on the the inappropriate placement of daughter cells along the anterior/posterior axis during vulval development." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002011" ; a owl:Class ; rdfs:label "bivulva" ; rdfs:subClassOf obo:WBPhenotype_0000695 . obo:WBPhenotype_0002012 obo:IAO_0000115 "Any variation in the process of chromosome organization that is involved in meiosis, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002012" ; a owl:Class ; rdfs:label "meiotic chromosome organization variant" ; rdfs:subClassOf obo:WBPhenotype_0000775 . obo:WBPhenotype_0002013 obo:IAO_0000115 "Chromosomes fails to pair with homologous chromosomes during the prophase stage of meiosis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002013" ; a owl:Class ; rdfs:label "univalent meiotic chromosomes" ; rdfs:subClassOf obo:WBPhenotype_0002012 . obo:WBPhenotype_0002014 obo:IAO_0000115 "Any observed variation in the measurement of current across the cell membrane compared to measurements in control animals. Current is a flow of electric charge through a medium." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002014" ; a owl:Class ; rdfs:label "current measurement variant" ; rdfs:subClassOf obo:WBPhenotype_0001315 . obo:WBPhenotype_0002015 obo:IAO_0000115 "Any observed variation in the measurement of voltage across the cell membrane compared to measurements in control animals. Voltage is the difference in electric potential energy per unit charge between two points." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002015" ; a owl:Class ; rdfs:label "voltage measurement variant" ; rdfs:subClassOf obo:WBPhenotype_0001315 . obo:WBPhenotype_0002016 obo:IAO_0000115 "Failure to execute the characteristic response to biotin as defined by control animals. In C. elegans, biotin is typically an attractant." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002016" ; a owl:Class ; rdfs:label "biotin chemotaxis defective" ; rdfs:subClassOf obo:WBPhenotype_0001441 . obo:WBPhenotype_0002017 obo:IAO_0000115 "Any variation in the ability of multipotent vulval precursor cells to respond to signals compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "vulval precursor cell competence abnormal", "vulval precursor cell competence variant" ; oboInOwl:id "WBPhenotype:0002017" ; a owl:Class ; rdfs:label "VPC competence variant" ; rdfs:subClassOf obo:WBPhenotype_0000216 . obo:WBPhenotype_0002018 obo:IAO_0000115 "Seam cells fuse to form a continuous syncytium along the body wall at a later stage of development compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002018" ; a owl:Class ; rdfs:label "retarded seam cell fusion" ; rdfs:subClassOf obo:WBPhenotype_0000166 . obo:WBPhenotype_0002019 obo:IAO_0000115 "Adult animals display a smaller number of eggs inside the uterus compared to controls" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002019" ; a owl:Class ; rdfs:label "fewer eggs in utero" ; rdfs:subClassOf obo:WBPhenotype_0000624 . obo:WBPhenotype_0002020 obo:IAO_0000115 "Transmission of the signal along the neuron varies from control. This process includes the flow of information from the neuron cell body to the synapse and across to the postsynaptic cell." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002020" ; a owl:Class ; rdfs:label "transmission of nerve impulse variant" ; rdfs:subClassOf obo:WBPhenotype_0000612 . obo:WBPhenotype_0002021 obo:IAO_0000115 "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed at the synapse, which are independent of presynaptic inputs." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002021" ; a owl:Class ; rdfs:label "synaptic spike frequency variant" ; rdfs:subClassOf obo:WBPhenotype_0000584, obo:WBPhenotype_0002023 . obo:WBPhenotype_0002022 obo:IAO_0000115 "Calcium transients at presynaptic regions do not occur." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002022" ; a owl:Class ; rdfs:label "no synaptic spike frequency" ; rdfs:subClassOf obo:WBPhenotype_0002021 . obo:WBPhenotype_0002023 obo:IAO_0000115 "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed either at the cell body or the synaptic region, which are independent of presynaptic inputs." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002023" ; a owl:Class ; rdfs:label "spike frequency variant" ; rdfs:subClassOf obo:WBPhenotype_0002020 . obo:WBPhenotype_0002024 obo:IAO_0000115 "Animals exhibit variations in the autonomously initiated periodic trains of calcium transients observed in cell bodies, which are independent of presynaptic inputs." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002024" ; a owl:Class ; rdfs:label "cell body spike frequency variant" ; rdfs:subClassOf obo:WBPhenotype_0002023 . obo:WBPhenotype_0002025 obo:IAO_0000115 "The diameter, volume, or area taken up by a cell differs from that measured in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002025" ; a owl:Class ; rdfs:label "cell size decreased" ; rdfs:subClassOf obo:WBPhenotype_0000533 . obo:WBPhenotype_0002026 obo:IAO_0000115 "Animals differ from control animals in response to mechanical stimulation targeting different parts of the same cell. In N2 wild-type animals, response to touch near the ALM cell body is reduced compared with touch of the cell area near the second pharyngeal bulb." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002026" ; a owl:Class ; rdfs:label "differential touch sensitivity variant" ; rdfs:subClassOf obo:WBPhenotype_0000315 . obo:WBPhenotype_0002027 obo:IAO_0000115 "VPCs differentiate in the absence of inductive signals coming from the gonad." ; oboInOwl:hasExactSynonym "Gid" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002027" ; a owl:Class ; rdfs:label "gonad independent vulva differentiation" ; rdfs:subClassOf obo:WBPhenotype_0000354, obo:WBPhenotype_0001272 . obo:WBPhenotype_0002028 obo:IAO_0000115 "Animals differ from controls in their electrical response to mechanical stimulus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "MRC variant" ; oboInOwl:id "WBPhenotype:0002028" ; a owl:Class ; rdfs:label "mechanoreceptor current variant" ; rdfs:subClassOf obo:WBPhenotype_0000315 . obo:WBPhenotype_0002029 obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of metal ions within an organism compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002029" ; a owl:Class ; rdfs:label "metal homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0002030 obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of magnesium ions within an organism compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002030" ; a owl:Class ; rdfs:label "magnesium homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0002029 . obo:WBPhenotype_0002031 obo:IAO_0000115 "Exposure to carbohydrate binding gene products result in an altered action in comparison to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002031" ; a owl:Class ; rdfs:label "lectin response variant" ; rdfs:subClassOf obo:WBPhenotype_0000459, obo:WBPhenotype_0001210, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1990840 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_1990840 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002032 obo:IAO_0000115 "Animals differ from controls in the range, specificity, or presence of targets for exogenously applied lectins." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002032" ; a owl:Class ; rdfs:label "lectin binding variant" ; rdfs:subClassOf obo:WBPhenotype_0002031 . obo:WBPhenotype_0002033 obo:IAO_0000115 "Animals contain targets for exogenously applied lectins." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "ectopic lectin binding" ; oboInOwl:id "WBPhenotype:0002033" ; a owl:Class ; rdfs:label "lectin binding occurs" ; rdfs:subClassOf obo:WBPhenotype_0002031 . obo:WBPhenotype_0002034 obo:IAO_0000115 "Animals are not observed to contain targets for exogenously applied lectins." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002034" ; a owl:Class ; rdfs:label "lectin binding does not occur" ; rdfs:subClassOf obo:WBPhenotype_0002031 . obo:WBPhenotype_0002035 obo:IAO_0000115 "Exposure to lectin has no affect on the behavior, growth, or development of the animal compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002035" ; a owl:Class ; rdfs:label "resistant to lectin" ; rdfs:subClassOf obo:WBPhenotype_0002031 . obo:WBPhenotype_0002036 obo:IAO_0000115 "Exposure to lectin results in altered behavior, growth, or development of the animal compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002036" ; a owl:Class ; rdfs:label "susceptible to lectin" ; rdfs:subClassOf obo:WBPhenotype_0002031 . obo:WBPhenotype_0002037 obo:IAO_0000115 "The appearance and association of components along the double lipid bilayer enclosing the nucleus differs from controls. The NE separates nuclear contents from the rest of the cytoplasm and includes the intermembrane space, perinuclear space." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002037" ; a owl:Class ; rdfs:label "nuclear envelope organization variant" ; rdfs:subClassOf obo:WBPhenotype_0001028 . obo:WBPhenotype_0002038 obo:IAO_0000115 "Proteins show defects in their localization in the cilia compared to control animals." ; oboInOwl:hasBroadSynonym "cil" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002038" ; a owl:Class ; rdfs:label "ciliary localization defective" ; rdfs:subClassOf obo:WBPhenotype_0000851 . obo:WBPhenotype_0002039 obo:IAO_0000115 "Animals exhibit variation in the directed movement of organelles or molecules along microtubules from the cell periphery in nerve cell axons to the cell body, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002039" ; a owl:Class ; rdfs:label "retrograde transport variant" ; rdfs:subClassOf obo:WBPhenotype_0002563 . obo:WBPhenotype_0002040 obo:IAO_0000115 "Chromosomes are not segregated symmetrically during mitosis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "chaotic mitosis" ; oboInOwl:id "WBPhenotype:0002040" ; a owl:Class ; rdfs:label "asymmetric chromosome segregation" ; rdfs:subClassOf obo:WBPhenotype_0001378 . obo:WBPhenotype_0002041 obo:IAO_0000115 "Animals exhibit variation in timing or ability to molt." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002041" ; a owl:Class ; rdfs:label "molt variant" ; rdfs:subClassOf obo:WBPhenotype_0000750 . obo:WBPhenotype_0002042 obo:IAO_0000115 "Molting cycles do not occur in a temporally controlled manner and cannot be synchronized across a population." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002042" ; a owl:Class ; rdfs:label "molting arrhythmic" ; rdfs:subClassOf obo:WBPhenotype_0002041 . obo:WBPhenotype_0002043 obo:IAO_0000115 "The number of cross progeny produced by hermaphrodites is reduced compared to control hermaphrodites." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002043" ; a owl:Class ; rdfs:label "hermaphrodite mating efficiency reduced" ; rdfs:subClassOf obo:WBPhenotype_0004001 . obo:WBPhenotype_0002044 obo:IAO_0000115 "Hermaphrodites do not produce cross progeny." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002044" ; a owl:Class ; rdfs:label "hermaphrodite mating efficiency eliminated" ; rdfs:subClassOf obo:WBPhenotype_0002043 . obo:WBPhenotype_0002045 obo:IAO_0000115 "Animals exhibit fewer cell corpses compared to controls at the same developmental life stage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002045" ; a owl:Class ; rdfs:label "cell corpse number decreased" ; rdfs:subClassOf obo:WBPhenotype_0000590 . obo:WBPhenotype_0002046 obo:IAO_0000115 "Variations in the regulation of levels, transport, and metabolism of iron within an organism compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002046" ; a owl:Class ; rdfs:label "iron homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0002029 . obo:WBPhenotype_0002047 obo:IAO_0000115 "Animals exhibit variations in their response to muscimol compared to that observed in control animals. Muscimol is a GABA-A receptor agonist." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002047" ; a owl:Class ; rdfs:label "muscimol response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0002048 obo:IAO_0000115 "Animals survive longer, or do not respond to the same degree as control animals under similar conditions of abamectin exposure." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002048" ; a owl:Class ; rdfs:label "abamectin resistant" ; rdfs:subClassOf obo:WBPhenotype_0001502, obo:WBPhenotype_0002049, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_39214 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_39214 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002049 obo:IAO_0000115 "Animals are not affected to the same degree as control animals under similar conditions of abamectin exposure." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002049" ; a owl:Class ; rdfs:label "abamectin repsonse variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, obo:WBPhenotype_0001852 . obo:WBPhenotype_0002050 obo:IAO_0000115 "Animals are do not survive, or become paralyzed in the presence of abamectin." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002050" ; a owl:Class ; rdfs:label "abamectin sensitive" ; rdfs:subClassOf obo:WBPhenotype_0001918, obo:WBPhenotype_0002049, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_39214 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_39214 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002051 obo:IAO_0000115 "The production or regulation of ascaroside molecule populations differs from that of control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002051" ; a owl:Class ; rdfs:label "ascaroside biosynthesis variant" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0002052 obo:IAO_0000115 "Animals lack the ability to produce ascarosides that are capable of being produced in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002052" ; a owl:Class ; rdfs:label "ascaroside biosynthesis defective" ; rdfs:subClassOf obo:WBPhenotype_0002051 . obo:WBPhenotype_0002053 obo:IAO_0000115 "Animals fail to respond to or exhibit an attenuated response to ivermectin under conditions that elicits a response in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002053" ; a owl:Class ; rdfs:label "ivermectin resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, obo:WBPhenotype_0001856, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6078 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_6078 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002054 obo:IAO_0000115 "Animals exhibit an exaggerated response to magnesium compared to control animals exposed to similar concentrations." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002054" ; a owl:Class ; rdfs:label "magnesium hypersensitivity" ; rdfs:subClassOf obo:WBPhenotype_0000591, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25107 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25107 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002055 obo:IAO_0000115 "Animals do not exhibit light-induced currrents to the same extent or with the same quality as control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002055" ; a owl:Class ; rdfs:label "photocurrent defective" ; rdfs:subClassOf obo:WBPhenotype_0002014 . obo:WBPhenotype_0002056 obo:IAO_0000115 "Any variation in the specific actions or reactions of an organism causing an alteration in the ingestion of food compared to control animals. In C. elegans the main food source is bacteria and alterations in eating behavior usually lead to malnutrition." ; oboInOwl:hasExactSynonym "Eat" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002056" ; a owl:Class ; rdfs:label "eating variant" ; rdfs:subClassOf obo:WBPhenotype_0000659 . obo:WBPhenotype_0002057 obo:IAO_0000115 "Animals respond to Bacillus thuringiensis toxins (Bt toxins) at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002057" ; a owl:Class ; rdfs:label "Bacillus thuringiensis toxin hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010 . obo:WBPhenotype_0002058 obo:IAO_0000115 "Animals are not affected to the same degree as control animals under similar conditions of pore forming toxin exposure." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002058" ; a owl:Class ; rdfs:label "pore forming toxin response variant" ; rdfs:subClassOf obo:WBPhenotype_0000631, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0035915 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002059 obo:IAO_0000115 "Animals respond to pore forming toxins at a lower concentration or a shorter exposure compared to control animals. Increased susceptibility to pore forming toxins (e.g. Cry5B from Bacillus thuringiensis) is often measured by a decrease in the rate of survival in the presence of pore forming toxins compared to controls." ; oboInOwl:hasBroadSynonym "Hpo" ; oboInOwl:hasExactSynonym "hypersensitive to pore forming toxin" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002059" ; a owl:Class ; rdfs:label "pore forming toxin hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0002058 . obo:WBPhenotype_0002060 obo:IAO_0000115 "Animals fail to respond to the concentration of pore forming toxins that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002060" ; a owl:Class ; rdfs:label "pore forming toxin resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0002058 . obo:WBPhenotype_0002061 obo:IAO_0000115 "Any variation in the progressive decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002061" ; a owl:Class ; rdfs:label "chromosome decondensation variant" ; rdfs:subClassOf obo:WBPhenotype_0000536 . obo:WBPhenotype_0002062 obo:IAO_0000115 "The process of decompaction of chromatin that changes chromosome structure from the condensed form to a relaxed disperse form is abolished." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002062" ; a owl:Class ; rdfs:label "chromosome decondensation failure" ; rdfs:subClassOf obo:WBPhenotype_0002061 . obo:WBPhenotype_0002063 obo:IAO_0000115 "Animals differ from controls in the expression of genes targeted for silencing (gene inactivation) in subsequent generations via transcriptional or post-transcriptional processes." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002063" ; a owl:Class ; rdfs:label "maintenance of gene silencing variant" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0002064 obo:IAO_0000115 "Animals express genes that had been targeted for heritable silencing in previous generations." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002064" ; a owl:Class ; rdfs:label "maintenance of gene silencing defective" ; rdfs:subClassOf obo:WBPhenotype_0002063 . obo:WBPhenotype_0002065 obo:IAO_0000115 "Animals display variations in the manner in which the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) is remodeled, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002065" ; a owl:Class ; rdfs:label "basement membrane remodeling variant" ; rdfs:subClassOf obo:WBPhenotype_0000200, obo:WBPhenotype_0002588 . obo:WBPhenotype_0002066 obo:IAO_0000115 "Animals display variations in the manner in which an opening in the basement membrane (a thin, dense, sheet-like structure built on a network of polymeric laminin and type IV collagen) expands to make way for intertissue connections, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002066" ; a owl:Class ; rdfs:label "basement membrane gap expansion variant" ; rdfs:subClassOf obo:WBPhenotype_0002065 . obo:WBPhenotype_0002067 obo:IAO_0000115 "Animals differ from control animals in cortical actomyocin dynamics leading to internalization of endodermal precursor cells during gastrulation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002067" ; a owl:Class ; rdfs:label "apical constriction variant" ; rdfs:subClassOf obo:WBPhenotype_0000047 . obo:WBPhenotype_0002068 obo:IAO_0000115 "There is significantly less difference between the number of astral microtubles or other component(s) of the spindle microtuble organizing center at the anterior versus posterior poles of the spindle, than observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002068" ; a owl:Class ; rdfs:label "astral microtubule asymmetry defective" ; rdfs:subClassOf obo:WBPhenotype_0002419 . obo:WBPhenotype_0002069 obo:IAO_0000115 "Axons in animals do not end in the same manner as they do in control animals. Some defects described include an overextension of the axon or termination of the axon in the shape of a hook, either large or small." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002069" ; a owl:Class ; rdfs:label "axon termination defective" ; rdfs:subClassOf obo:WBPhenotype_0000180 . obo:WBPhenotype_0002070 obo:IAO_0000115 "Animals do not mimic control animals in their egg-laying response to muscimol exposure. In C. elegans, muscimol inhibits egg-laying." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002070" ; a owl:Class ; rdfs:label "egg laying response to muscimol variant" ; rdfs:subClassOf obo:WBPhenotype_0001101, obo:WBPhenotype_0002047 . obo:WBPhenotype_0002071 obo:IAO_0000115 "The length of the animal does not increase to the same extent as observed for control animals, in response to exposure to muscimol." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002071" ; a owl:Class ; rdfs:label "body lengthening response to muscimol variant" ; rdfs:subClassOf obo:WBPhenotype_0002047 . obo:WBPhenotype_0002072 obo:IAO_0000115 "Animals exhibit variations in any process that involves the maintenance, biosynthesis or accumulation of an internal store of carbohydrates within the organism or cell compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002072" ; a owl:Class ; rdfs:label "carbohydrate metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000027 . obo:WBPhenotype_0002073 obo:IAO_0000115 "Animals exhibit variations in the regulation of levels, transport, and metabolism of cations within a cell or between a cell and its external environment, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002073" ; a owl:Class ; rdfs:label "cation homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0002074 obo:IAO_0000115 "Animals vary in the directed or coordinated movement of their centrosomes during cell division, compared to the pattern of movement observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002074" ; a owl:Class ; rdfs:label "centrosome dynamics variant" ; rdfs:subClassOf obo:WBPhenotype_0000536 . obo:WBPhenotype_0002075 obo:IAO_0000115 "Embryos exhibit variations in the processes that lead to the construction of the eggshell, a protective structure that minimizes water loss whilst allowing gas exchanges essential for embryonic respiration, compared to controls" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002075" ; a owl:Class ; rdfs:label "eggshell formation variant" ; rdfs:subClassOf obo:WBPhenotype_0000041, obo:WBPhenotype_0000258 . obo:WBPhenotype_0002076 obo:IAO_0000115 "The process of secretion by a cell that results in the release of intracellular molecules contained within a specialized secretory vesicle that fuses with the plasma membrane during egg activation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002076" ; a owl:Class ; rdfs:label "cortical granule exocytosis variant" ; rdfs:subClassOf obo:WBPhenotype_0002075 . obo:WBPhenotype_0002077 obo:IAO_0000115 "Animals fail to respond to the concentration of a dopamine that elicits a response in control animals. Alternatively, animals require increased concentration or longer exposure to this compound to elicit the response compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002077" ; a owl:Class ; rdfs:label "dopamine resistant" ; rdfs:subClassOf obo:WBPhenotype_0000011, obo:WBPhenotype_0001502, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18243 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001650 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18243 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002078 obo:IAO_0000115 "The pattern or state of methyl modifications of histone varies from that of controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "methylation mark variant" ; oboInOwl:id "WBPhenotype:0002078" ; a owl:Class ; rdfs:label "histone methylation variant" ; rdfs:subClassOf obo:WBPhenotype_0001383 . obo:WBPhenotype_0002079 obo:IAO_0000115 "The animal's ability to reproduce, or start of reproduction occurs later than that observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002079" ; a owl:Class ; rdfs:label "delayed reproductive maturity" ; rdfs:subClassOf obo:WBPhenotype_0000045 . obo:WBPhenotype_0002080 obo:IAO_0000115 "Animals exhibit variations in the degree to which or manner in which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002080" ; a owl:Class ; rdfs:label "peptide uptake by intestinal cell variant" ; rdfs:subClassOf obo:WBPhenotype_0001763 . obo:WBPhenotype_0002081 obo:IAO_0000115 "Animals exhibit an increase in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002081" ; a owl:Class ; rdfs:label "peptide uptake by intestinal cell increased" ; rdfs:subClassOf obo:WBPhenotype_0002080 . obo:WBPhenotype_0002082 obo:IAO_0000115 "Animals exhibit a decrease in the degree to which an intestinal cell is able to uptake peptides (for example, di- or tripeptides) from the intestinal lumen, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002082" ; a owl:Class ; rdfs:label "peptide uptake by intestinal cell decreased" ; rdfs:subClassOf obo:WBPhenotype_0002080 . obo:WBPhenotype_0002083 obo:IAO_0000115 "The frequency and distribution of crossover events differs from that observed for controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002083" ; a owl:Class ; rdfs:label "crossover variant" ; rdfs:subClassOf obo:WBPhenotype_0002012 . obo:WBPhenotype_0002084 obo:IAO_0000115 "Animals differ from controls in respect to the frequency of expected double crossover events observed." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002084" ; a owl:Class ; rdfs:label "crossover interference variant" ; rdfs:subClassOf obo:WBPhenotype_0002083 . obo:WBPhenotype_0002085 obo:IAO_0000115 "The number of crossover events differs from that of observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002085" ; a owl:Class ; rdfs:label "crossover formation variant" ; rdfs:subClassOf obo:WBPhenotype_0002083 . obo:WBPhenotype_0002086 obo:IAO_0000115 "The location-specific frequency of crossover events differs from that of observed in control animals, while the total number of crossover events does not significantly differ." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002086" ; a owl:Class ; rdfs:label "crossover distribution variant" ; rdfs:subClassOf obo:WBPhenotype_0002083 . obo:WBPhenotype_0002087 obo:IAO_0000115 "Animals respond to hydrogen sulfide at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002087" ; a owl:Class ; rdfs:label "hydrogen sulfide hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000010, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_16136 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_16136 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002088 obo:IAO_0000115 "Animals respond to dauer pheromone at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002088" ; a owl:Class ; rdfs:label "hypersensitive to dauer pheromone" ; rdfs:subClassOf obo:WBPhenotype_0001479 . obo:WBPhenotype_0002089 obo:IAO_0000115 "Any variation in the form or composition of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002089" ; a owl:Class ; rdfs:label "cell component morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000533, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005575 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005575 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002090 obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as endosomes, that traffic material between the plasma membrane and internal compartments of the cell, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002090" ; a owl:Class ; rdfs:label "endosome morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0001323, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005768 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005768 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002091 obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as late endosomes, that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002091" ; a owl:Class ; rdfs:label "late endosome morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002090, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005770 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005770 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002092 obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002092" ; a owl:Class ; rdfs:label "early endosome morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002090, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005769 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005769 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002093 obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002093" ; a owl:Class ; rdfs:label "recycling endosome morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002090, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0055037 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0055037 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002094 obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002094" ; a owl:Class ; rdfs:label "RAB-11 recycling endosome morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002093 . obo:WBPhenotype_0002095 obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002095" ; a owl:Class ; rdfs:label "lysosome-related organelle morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002089 . obo:WBPhenotype_0002096 obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002096" ; a owl:Class ; rdfs:label "golgi apparatus morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005794 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002097 obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002097" ; a owl:Class ; rdfs:label "lysosome morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002089, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005764 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0005764 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002098 obo:IAO_0000115 "Any variation in the subcellular localization of the basic structural and functional components of cells compared to control. Includes the nucleus, endoplasmic reticulum, Golgi apparatus, mitochondria, endosomes, lysosomes, and peroxisomes as well as other vesicles and organelles." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002098" ; a owl:Class ; rdfs:label "cell component localization variant" ; rdfs:subClassOf obo:WBPhenotype_0000533 . obo:WBPhenotype_0002099 obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002099" ; a owl:Class ; rdfs:label "lysosome-related organelle localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002098 . obo:WBPhenotype_0002100 obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as endosomes, that traffic material between the plasma membrane and internal compartments of the cell, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002100" ; a owl:Class ; rdfs:label "endosome localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002098 . obo:WBPhenotype_0002101 obo:IAO_0000115 "Any variation in the subcellular localization of the endoplasmic reticulum compared to control. The endoplasmic reticulum (ER) is an irregular network of membranes, that exists in the cytoplasm, and forms a complex meshwork of tubular channels. The ER has two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002101" ; a owl:Class ; rdfs:label "endoplasmic reticulum localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002098 . obo:WBPhenotype_0002102 obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as the Golgi apparatus, that traffic material from the endoplasmic reticulum or various endosomes, and process proteins for secretion, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002102" ; a owl:Class ; rdfs:label "golgi apparatus localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002098 . obo:WBPhenotype_0002103 obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as lysosomes, that have an acidic interior and generally act to digest components of the cell, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002103" ; a owl:Class ; rdfs:label "lysosome localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002098 . obo:WBPhenotype_0002104 obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002104" ; a owl:Class ; rdfs:label "recycling endosome localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002100 . obo:WBPhenotype_0002105 obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as late endosomes, that traffic material from early endosomes to internal compartments of the cell, such as lysosomes or the Golgi apparatus, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002105" ; a owl:Class ; rdfs:label "late endosome localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002100 . obo:WBPhenotype_0002106 obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as early endosomes, that traffic material from endocytic vesicles (having recently internalized portions of the cell's plasma membrane) to internal compartments of the cell, such as recycling endosomes, late endosomes, or the Golgi apparatus, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002106" ; a owl:Class ; rdfs:label "early endosome localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002100 . obo:WBPhenotype_0002107 obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002107" ; a owl:Class ; rdfs:label "RAB-11 recycling endosome localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002104 . obo:WBPhenotype_0002108 obo:IAO_0000115 "Any variation in the form or composition of specialized cell types, compared to control. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002108" ; a owl:Class ; rdfs:label "cell type morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000533 . obo:WBPhenotype_0002109 obo:IAO_0000115 "Animals are affected by exposure to the drug." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002109" ; a owl:Class ; rdfs:label "drug susceptible" ; rdfs:subClassOf obo:WBPhenotype_0000631 . obo:WBPhenotype_0002110 obo:IAO_0000115 "Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002110" ; a owl:Class ; rdfs:label "RME-1 recycling endosome morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002093 . obo:WBPhenotype_0002111 obo:IAO_0000115 "Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the endocytosis protein RME-1, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002111" ; a owl:Class ; rdfs:label "RME-1 recycling endosome localization variant" ; rdfs:subClassOf obo:WBPhenotype_0002104 . obo:WBPhenotype_0002112 obo:IAO_0000115 "Animals are unable to maintain paired chromosome throughout pachytene." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002112" ; a owl:Class ; rdfs:label "synapsis maintenance defective" ; rdfs:subClassOf obo:WBPhenotype_0002012 . obo:WBPhenotype_0002113 obo:IAO_0000115 "Animals differ from controls in respect to the formation of paired chromosome loci." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002113" ; a owl:Class ; rdfs:label "synapsis formation variant" ; rdfs:subClassOf obo:WBPhenotype_0002012 . obo:WBPhenotype_0002114 obo:IAO_0000115 "Animals become paralyzed after a measured amount of time swimming. In C. elegans, more then 80 percent of wild-type animals continue swimming vigorously in liquid even after 30 minutes." ; oboInOwl:hasBroadSynonym "SWIP" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002114" ; a owl:Class ; rdfs:label "swimming induced paralysis" ; rdfs:subClassOf obo:WBPhenotype_0001700 . obo:WBPhenotype_0002115 obo:IAO_0000115 "Animals do not avoid, and perhaps seek, environments that result in their death. In the case of C. elegans, this behavior is exemplified by animals that tend to crawl off the plate." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002115" ; a owl:Class ; rdfs:label "suicidal" ; rdfs:subClassOf obo:WBPhenotype_0000888 . obo:WBPhenotype_0002116 obo:IAO_0000115 "Animals are barely alive, but not entirely dead." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002116" ; a owl:Class ; rdfs:label "subviable" ; rdfs:subClassOf obo:WBPhenotype_0000531, obo:WBPhenotype_0000576 . obo:WBPhenotype_0002117 obo:IAO_0000115 "Animals exhibit constrictions in the anterior portion of the head that result in decapitation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002117" ; a owl:Class ; rdfs:label "occurences of decapitation" ; rdfs:subClassOf obo:WBPhenotype_0000212 . obo:WBPhenotype_0002118 obo:IAO_0000115 "Populations exhibit variations in the ability to survive, grow and reproduce, thus affecting the contribution to the gene pool over generations compared to control populations. In C. elegans the fitness of a population can by assessed by measuring the rate at which E. coli is consumed." ; oboInOwl:hasExactSynonym "population fitness variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002118" ; a owl:Class ; rdfs:label "population fitness phenotype" ; rdfs:subClassOf obo:WBPhenotype_0000519 . obo:WBPhenotype_0002119 obo:IAO_0000115 "The process of generating multiple mRNA molecules from differential use of exons in a primary transcript(s) does not occur or occurs with outcomes not observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002119" ; a owl:Class ; rdfs:label "alternative splicing defective" ; rdfs:subClassOf obo:WBPhenotype_0001807 . obo:WBPhenotype_0002120 obo:IAO_0000115 "Any variation in the process of restoring mitochondrial DNA after damage." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002120" ; a owl:Class ; rdfs:label "mitochondrial DNA repair variant" ; rdfs:subClassOf obo:WBPhenotype_0001938 . obo:WBPhenotype_0002121 obo:IAO_0000115 "The presence of a mixture of more than one type of an organellar genome (mitochondrial DNA (mtDNA) or plastid DNA) within a cell or individual." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002121" ; a owl:Class ; rdfs:label "heteroplasmy" ; rdfs:subClassOf obo:WBPhenotype_0000576 . obo:WBPhenotype_0002122 obo:IAO_0000115 "Mitochondria from spermatazoa persist in the developing embryo and animal as a result of bypassing the degradation mechanism that normally destroys paternal mitochondria immediately after fertilization. This can often lead to a form of heteroplasmy." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002122" ; a owl:Class ; rdfs:label "persistence of paternal mitochondria" ; rdfs:subClassOf obo:WBPhenotype_0002121 . obo:WBPhenotype_0002123 obo:IAO_0000115 "The pattern or state of acetylation modifications of histones varies from that of controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002123" ; a owl:Class ; rdfs:label "histone acetylation variant" ; rdfs:subClassOf obo:WBPhenotype_0001917 . obo:WBPhenotype_0002124 obo:IAO_0000115 "The distribution or presence of actin in circumferential actin bundles (CFB) differs from that observed in control animals. Contraction of CFBs provide the driving force for epidermal elongation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002124" ; a owl:Class ; rdfs:label "circumferential actin bundles disorganized" ; rdfs:subClassOf obo:WBPhenotype_0001587 . obo:WBPhenotype_0002125 obo:IAO_0000115 "Animals do not grow fast or the quality of growth is decreased when exposed to a specific chemical compound when compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002125" ; a owl:Class ; rdfs:label "growth inhibition response to chemical" ; rdfs:subClassOf obo:WBPhenotype_0000523 . obo:WBPhenotype_0002126 obo:IAO_0000115 "Animals exhibit a decrease in the accumulation or expression of biochromes or any other substances that fluoresce in the intestine." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002126" ; a owl:Class ; rdfs:label "intestinal fluorescence decreased" ; rdfs:subClassOf obo:WBPhenotype_0000293 . obo:WBPhenotype_0002127 obo:IAO_0000115 "Animals exhibit variation rate of directed movement of organelles or molecules along microtubules in nerve cell axons, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002127" ; a owl:Class ; rdfs:label "intraflagellar transport velocity variant" ; rdfs:subClassOf obo:WBPhenotype_0000853 . obo:WBPhenotype_0002128 obo:IAO_0000115 "Males remain on food in the absence of mates, a defect in male mate-searching behavior observed in control males." ; oboInOwl:hasBroadSynonym "Las" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002128" ; a owl:Class ; rdfs:label "leaving assay defective" ; rdfs:subClassOf obo:WBPhenotype_0001983, obo:WBPhenotype_0004031 . obo:WBPhenotype_0002129 obo:IAO_0000115 "Relative levels of mtDNA differ from that observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002129" ; a owl:Class ; rdfs:label "mitochondrial DNA copy number variant" ; rdfs:subClassOf obo:WBPhenotype_0000732, obo:WBPhenotype_0001282 . obo:WBPhenotype_0002130 obo:IAO_0000115 "Males exhibit variations of the behaviors observed in control animals that follow the completion of mating." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "mate experience variant" ; oboInOwl:id "WBPhenotype:0002130" ; a owl:Class ; rdfs:label "post mating variant" ; rdfs:subClassOf obo:WBPhenotype_0000648 . obo:WBPhenotype_0002131 obo:IAO_0000115 "Animals display variations in the structure or organization of the components of the muscle, compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002131" ; a owl:Class ; rdfs:label "muscle cell ultrastructure variant" ; rdfs:subClassOf obo:WBPhenotype_0000904 . obo:WBPhenotype_0002132 obo:IAO_0000115 "The formation, organization, or stability of a protein complex is altered in comparison to corresponding complexes in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "protein clustering variant" ; oboInOwl:id "WBPhenotype:0002132" ; a owl:Class ; rdfs:label "protein complex organization variant" ; rdfs:subClassOf obo:WBPhenotype_0001370 . obo:WBPhenotype_0002133 obo:IAO_0000115 "The bulk flow of cytoplasm in the egg, that facilitates mixing of ooplasm, occurs at a reduced rate compared to that measured for controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002133" ; a owl:Class ; rdfs:label "ooplasmic streaming slow" ; rdfs:subClassOf obo:WBPhenotype_0000360 . obo:WBPhenotype_0002134 obo:IAO_0000115 "Animals are less successful than controls in evading predators during predator-prey interactions." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002134" ; a owl:Class ; rdfs:label "predator escape defective" ; rdfs:subClassOf obo:WBPhenotype_0002135 . obo:WBPhenotype_0002135 obo:IAO_0000115 "Predator-prey interactions differ from that observed in control interactions." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002135" ; a owl:Class ; rdfs:label "organism predator response variant" ; rdfs:subClassOf obo:WBPhenotype_0000738 . obo:WBPhenotype_0002136 obo:IAO_0000115 "Animals are missing the anchor cell. In C. elegans the anchor cell is a key organizer of vulval patterning and morphogenesis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002136" ; a owl:Class ; rdfs:label "no anchor cell" ; rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0002174, obo:WBPhenotype_0002552, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004522 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000462 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0004522 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002137 obo:IAO_0000115 "The rate of the process preceding formation of the peptide bond between the first two amino acids of a protein is reduced. This process includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. Increase in free ribosomes (monosomes) are indicative of reduced translation initiation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002137" ; a owl:Class ; rdfs:label "reduced translation initiation" ; rdfs:subClassOf obo:WBPhenotype_0000121 . obo:WBPhenotype_0002138 obo:IAO_0000115 "Animals are altered in their capacity to survive a normally lethal temperature treatment as a consequence of pretreatment at an elevated but sublethal temperature." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002138" ; a owl:Class ; rdfs:label "acquired thermotolerance variant" ; rdfs:subClassOf obo:WBPhenotype_0000146 . obo:WBPhenotype_0002139 obo:IAO_0000115 "Any variation in the morphological appearance of the linker cell compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002139" ; a owl:Class ; rdfs:label "linker cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0002108, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005062 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005062 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002140 obo:IAO_0000115 "Males do not respond to small molecules or compounds that have been shown to attract control males. This phenotype is often measured by an increase in reversal frequency or time spent in a specified scoring region" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002140" ; a owl:Class ; rdfs:label "male attraction response variant" ; rdfs:subClassOf obo:WBPhenotype_0000738 . obo:WBPhenotype_0002141 obo:IAO_0000115 "Variations in the process of gaseous oxygen intake between an organism and its environment compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002141" ; a owl:Class ; rdfs:label "oxygen consumption variant" ; rdfs:subClassOf obo:WBPhenotype_0001835 . obo:WBPhenotype_0002142 obo:IAO_0000115 "The activity, composition, or organization of the complexes of the electron transport chain, embedded in the inner mitochondrial membrane, differ from controls." ; oboInOwl:hasExactSynonym "MRC variant", "mitochondrial electron transport chain variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002142" ; a owl:Class ; rdfs:label "mitochondrial respiratory chain variant" ; rdfs:subClassOf obo:WBPhenotype_0001282 . obo:WBPhenotype_0002143 obo:IAO_0000115 "The part of the respiratory chain that catalyzes the oxidation of succinate and connects the TCA cycle with the respiratory chain, differs in activity, composition, or organization, from that of controls." ; oboInOwl:hasExactSynonym "CO II variant", "Complex II variant", "Succinate dehydrogenase complex variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002143" ; a owl:Class ; rdfs:label "mitochondrial respiratory complex II variant" ; rdfs:subClassOf obo:WBPhenotype_0002142 . obo:WBPhenotype_0002144 obo:IAO_0000115 "The protein complex located in the mitochondrial inner membrane that is the first entry point for electrons into the electron transport chain and catalyzes proton translocation coupled to the oxidation of NADH by ubiquinone, differs in activity, composition, or organization from that of controls." ; oboInOwl:hasExactSynonym "CO I variant", "Complex I variant", "NADH dehydrogenase complex variant", "Ubiquinone complex variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002144" ; a owl:Class ; rdfs:label "mitochondrial respiratory complex I variant" ; rdfs:subClassOf obo:WBPhenotype_0002142 . obo:WBPhenotype_0002145 obo:IAO_0000115 "Animals are unable to produce or maintain short interfering RNA (siRNA) from double stranded RNA (dsRNA). siRNAs are required to initiate interference of gene expression." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002145" ; a owl:Class ; rdfs:label "siRNA processing defective" ; rdfs:subClassOf obo:WBPhenotype_0000743, obo:WBPhenotype_0001776 . obo:WBPhenotype_0002146 obo:IAO_0000115 "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in the germline. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002146" ; a owl:Class ; rdfs:label "small RNA germline expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000113 . obo:WBPhenotype_0002147 obo:IAO_0000115 "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of any class of small RNA species in somatic cells. Small RNAs include microRNAs (miRNAs), tiny noncoding RNAs (tncRNAs), cluster of small X-chromosome derived RNAs (X cluster), and endogenous short interfering RNA (endo-siRNAs)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002147" ; a owl:Class ; rdfs:label "small RNA somatic expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000113 . obo:WBPhenotype_0002148 obo:IAO_0000115 "Animals show reduced susceptibility to gene silencing in somatic cells triggered by double stranded RNA (dsRNA), compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002148" ; a owl:Class ; rdfs:label "somatic RNAi resistant" ; rdfs:subClassOf obo:WBPhenotype_0001208 . obo:WBPhenotype_0002149 obo:IAO_0000115 "Animals exhibit variations from controls in the expression, biogenesis, processing, or stability of the small X-chromosome derived RNAs (X cluster) species of small RNA." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002149" ; a owl:Class ; rdfs:label "X cluster small RNA expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000113 . obo:WBPhenotype_0002150 obo:IAO_0000115 "RNAi silencing mechanisms triggered by exogenously introduced (foreign) dsRNA, do not work to the same degree as in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002150" ; a owl:Class ; rdfs:label "exo-RNAi response variant" ; rdfs:subClassOf obo:WBPhenotype_0000743 . obo:WBPhenotype_0002151 obo:IAO_0000115 "Animals exhibit variations in the extent to which polyadenylated mRNA transcripts become deadenylated" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002151" ; a owl:Class ; rdfs:label "mRNA deadenylation variant" ; rdfs:subClassOf obo:WBPhenotype_0001827 . obo:WBPhenotype_0002152 obo:IAO_0000115 "Programmed cell death of germ cells caused by exposure to physical or chemical DNA-damaging agents does not occur to the same extent as it does in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002152" ; a owl:Class ; rdfs:label "mutagen induced apoptosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000730 . obo:WBPhenotype_0002153 obo:IAO_0000115 "The production of silencing RNA from dsRNA is significantly deficient compared to controls. Deficiencies in this process can result in a defective RNAi response compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002153" ; a owl:Class ; rdfs:label "dsRNA processing defective" ; rdfs:subClassOf obo:WBPhenotype_0000028 . obo:WBPhenotype_0002154 obo:IAO_0000115 "The extent of mRNA ribosome associations varies from controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002154" ; a owl:Class ; rdfs:label "polysome mRNA association variant" ; rdfs:subClassOf obo:WBPhenotype_0000121, obo:WBPhenotype_0001371 . obo:WBPhenotype_0002155 obo:IAO_0000115 "The production of mature miRNA from pre-miRNA is significantly deficient compared to controls. Deficiencies in this process can result in the accumulation of pre-miRNA species and or the absence or smaller amount of mature miRNA compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002155" ; a owl:Class ; rdfs:label "pre miRNA processing defective" ; rdfs:subClassOf obo:WBPhenotype_0000028, obo:WBPhenotype_0002528 . obo:WBPhenotype_0002156 obo:IAO_0000115 "Wild-type animals will exhibit an altered temperature preference based on food/temperature conditioning. Temperature learning variants do not exhibit altered responses to temperature after conditioning compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002156" ; a owl:Class ; rdfs:label "temperature learning variant" ; rdfs:subClassOf obo:WBPhenotype_0001780 . obo:WBPhenotype_0002157 obo:IAO_0000115 "The extent of translational repression varies from controls." ; oboInOwl:hasAlternativeId "WBPhenotype:0001909" ; oboInOwl:hasExactSynonym "translational repression variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002157" ; a owl:Class ; rdfs:label "translation repression variant" ; rdfs:subClassOf obo:WBPhenotype_0000121 . obo:WBPhenotype_0002158 obo:IAO_0000115 "The selective elimination of P granule components and subsequent aggregation of degraded components into PGL granules is disrupted." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002158" ; a owl:Class ; rdfs:label "P granule degradation defective" ; rdfs:subClassOf obo:WBPhenotype_0001301 . obo:WBPhenotype_0002159 obo:IAO_0000115 "Animals exhibit an increase in pathogen accumulation, persistent colonization, and luminal distension of the intestine." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002159" ; a owl:Class ; rdfs:label "increased pathogen accumulation" ; rdfs:subClassOf obo:WBPhenotype_0001819 . obo:WBPhenotype_0002160 obo:IAO_0000115 "The intracellular complex of proteins that participates in bidirectional transport of molecules (cargo) along axonemal microtubules is not made up of or does not maintain the proper number or ratio of components as found in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002160" ; a owl:Class ; rdfs:label "intraflagellar transport complex destabilized" ; rdfs:subClassOf obo:WBPhenotype_0002132 . obo:WBPhenotype_0002161 obo:IAO_0000115 "Animals exhibit variations from controls in the organization of chromatin, including in relation to associated complexes, that occur during the mitotic cell division cycle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002161" ; a owl:Class ; rdfs:label "mitotic chromatin remodeling variant" ; rdfs:subClassOf obo:WBPhenotype_0001348, obo:WBPhenotype_0001743 . obo:WBPhenotype_0002162 obo:IAO_0000115 "Cells exhibit mitotic spindles with more than two poles." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "multipolar mitosis" ; oboInOwl:id "WBPhenotype:0002162" ; a owl:Class ; rdfs:label "multipolar mitotic spindle" ; rdfs:subClassOf obo:WBPhenotype_0001215, obo:WBPhenotype_0001743 . obo:WBPhenotype_0002163 obo:IAO_0000115 "Animals exhibit a decreased rate of oxygen utilization compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002163" ; a owl:Class ; rdfs:label "oxygen consumption decreased" ; rdfs:subClassOf obo:WBPhenotype_0002141 . obo:WBPhenotype_0002164 obo:IAO_0000115 "Animals exhibit variations in their defense responses that are mediated by germline encoded components that directly recognize components of potential pathogens." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002164" ; a owl:Class ; rdfs:label "innate immune response variant" ; rdfs:subClassOf obo:WBPhenotype_0001012, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045087 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0045087 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002165 obo:IAO_0000115 "The extent or other quality of the excitatory postsynaptic potential (EPSP) induced by in vitro stimuli differs from that of controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002165" ; a owl:Class ; rdfs:label "muscle excitability variant" ; rdfs:subClassOf obo:WBPhenotype_0001735, obo:WBPhenotype_0002014 . obo:WBPhenotype_0002166 obo:IAO_0000115 "The difference in electrical potential between the interior and the exterior of the muscle cell either in the resting state or during evoked stimulation differs from controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002166" ; a owl:Class ; rdfs:label "muscle membrane potential variant" ; rdfs:subClassOf obo:WBPhenotype_0000990, obo:WBPhenotype_0001965 . obo:WBPhenotype_0002167 obo:IAO_0000115 "The amount of histone methylation, for example as measured by the amount of H3K4me2, increases over successive generations" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "generational accumulation of histone methylation", "progressive accumulation of histone methylation", "transgenerational epigenetic accumulation of histone methylation" ; oboInOwl:id "WBPhenotype:0002167" ; a owl:Class ; rdfs:label "transgenerational accumulation of histone methylation" ; rdfs:subClassOf obo:WBPhenotype_0002078 . obo:WBPhenotype_0002168 obo:IAO_0000115 "Animals exhibit a decline in fertility over generations. This is often assessed by counting laid eggs over successive generations." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "generational loss of fertility", "progressive loss of fertility", "transgenerational epigenetic loss of fertility" ; oboInOwl:id "WBPhenotype:0002168" ; a owl:Class ; rdfs:label "transgenerational loss of fertility" ; rdfs:subClassOf obo:WBPhenotype_0000145 . obo:WBPhenotype_0002169 obo:IAO_0000115 "Animals stop producing progeny significantly before the time reproduction stops in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002169" ; a owl:Class ; rdfs:label "reproductive longevity shortened" ; rdfs:subClassOf obo:WBPhenotype_0001739 . obo:WBPhenotype_0002170 obo:IAO_0000115 "Any variation in the series of molecular signals in which a cell or tissue uses calcium ions to convert a signal into a response, compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002170" ; a owl:Class ; rdfs:label "calcium mediated signaling variant" ; rdfs:subClassOf obo:WBPhenotype_0000536 . obo:WBPhenotype_0002171 obo:IAO_0000115 "Animals exhibit variations in the characteristic movement towards typically attractive alkaline pH (pH higher than 7) compared to control. However animals tend to avoid very high pH levels (pH11). pH is a measure of the acidity or basicity of an aqueous solution. In C. elegans animals chemotax toward higher alkaline pH." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:hasRelatedSynonym "alkaline pH sensing variant", "alkalinity sensing variant" ; oboInOwl:id "WBPhenotype:0002171" ; a owl:Class ; rdfs:label "alkaline pH chemotaxis variant" ; rdfs:subClassOf obo:WBPhenotype_0001047 . obo:WBPhenotype_0002172 obo:IAO_0000115 "Infected animals exhibit variations in the process of releasing pathogens back into the environment, compared to control." ; oboInOwl:hasNarrowSynonym "spore shedding variant" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002172" ; a owl:Class ; rdfs:label "pathogen release variant" ; rdfs:subClassOf obo:WBPhenotype_0001012 . obo:WBPhenotype_0002173 obo:IAO_0000115 "Animals exhibit variations in the number of cells that make up the organism compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002173" ; a owl:Class ; rdfs:label "cell number variant" ; rdfs:subClassOf obo:WBPhenotype_0000531 . obo:WBPhenotype_0002174 obo:IAO_0000115 "The number of cells in the organism is reduced compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002174" ; a owl:Class ; rdfs:label "cell number decreased" ; rdfs:subClassOf obo:WBPhenotype_0002173 . obo:WBPhenotype_0002175 obo:IAO_0000115 "The number of cells in the organism is increased compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002175" ; a owl:Class ; rdfs:label "cell number increased" ; rdfs:subClassOf obo:WBPhenotype_0002173 . obo:WBPhenotype_0002176 obo:IAO_0000115 "Animals exhibit variations in the structure, organization or placement of the population of the lateral, alae-producing epithelial cells (seam cells), compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002176" ; a owl:Class ; rdfs:label "seam cell morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000899, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005753 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0000051 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:WBbt_0005753 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002177 obo:IAO_0000115 "Any variation in the components that make up the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002177" ; a owl:Class ; rdfs:label "plasma membrane composition variant" ; rdfs:subClassOf obo:WBPhenotype_0000536 . obo:WBPhenotype_0002178 obo:IAO_0000115 "Any variation in the components that make up either of the two leaflets of the semipermeable bilayer surrounding a cell that separates the cell from its external environment compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002178" ; a owl:Class ; rdfs:label "plasma membrane leaflet composition variant" ; rdfs:subClassOf obo:WBPhenotype_0002177 . obo:WBPhenotype_0002179 obo:IAO_0000115 "Animals do not arrest mitotic germ cell division, as control animals, when treated with X-ray radiation." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002179" ; a owl:Class ; rdfs:label "X ray induced mitotic germ cell arrest defective" ; rdfs:subClassOf obo:WBPhenotype_0001324 . obo:WBPhenotype_0002180 obo:IAO_0000115 "Animals exhibit variations in the process by which cells having undergone programmed cell death are shed or extruded into the extracellular environment." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002180" ; a owl:Class ; rdfs:label "apoptotic cell shedding variant" ; rdfs:subClassOf obo:WBPhenotype_0000730 . obo:WBPhenotype_0002181 obo:IAO_0000115 "Animals produce an excess number of excretory cells compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002181" ; a owl:Class ; rdfs:label "extra excretory cells" ; rdfs:subClassOf obo:WBPhenotype_0000621, obo:WBPhenotype_0002175 . obo:WBPhenotype_0002182 obo:IAO_0000115 "Animals exhibit variations in endogenous levels of reactive oxygen species (chemically reactive molecules containing oxygen) compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002182" ; a owl:Class ; rdfs:label "reactive oxygen species homeostasis variant" ; rdfs:subClassOf obo:WBPhenotype_0000577 . obo:WBPhenotype_0002183 obo:IAO_0000115 "Animals exhibit variations in levels of DNA damage caused by oxidative stress." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002183" ; a owl:Class ; rdfs:label "oxidative DNA damage variant" ; rdfs:subClassOf obo:WBPhenotype_0000732 . obo:WBPhenotype_0002184 obo:IAO_0000115 "Any variation in the amount of cells undergoing apoptosis in organism as a result of deprivation of nourishment, compared to control. In C. elegans, starvation normally causes increased apoptosis." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002184" ; a owl:Class ; rdfs:label "starvation induced apoptosis variant" ; rdfs:subClassOf obo:WBPhenotype_0000147, obo:WBPhenotype_0000730 . obo:WBPhenotype_0002185 obo:IAO_0000115 "Animals develop endodermal cells/tissue from precursor cells that do not normally produce endodermal cells/tissue." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002185" ; a owl:Class ; rdfs:label "cell fate transformation to endoderm" ; rdfs:subClassOf obo:WBPhenotype_0000414 . obo:WBPhenotype_0002186 obo:IAO_0000115 "Animals develop pharyngeal muscles from precursor cells that do not normally produce pharyngeal muscles." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002186" ; a owl:Class ; rdfs:label "cell fate transformation to pharyngeal muscle" ; rdfs:subClassOf obo:WBPhenotype_0000414 . obo:WBPhenotype_0002187 obo:IAO_0000115 "Animals develop body wall muscle from precursor cells that do not normally produce body wall muscle." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002187" ; a owl:Class ; rdfs:label "cell fate transformation to body wall muscle" ; rdfs:subClassOf obo:WBPhenotype_0000414 . obo:WBPhenotype_0002188 obo:IAO_0000115 "Any variation in the progression of the components of the male gonad that are separate from the germline proper over time, from its formation to its mature structure compared to control. In C. elegans, the male somatic gonad consists of three tissues: distal tip cells (DTCs), the seminal vesicle, and the vas deferens (Wormatlas)." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002188" ; a owl:Class ; rdfs:label "male somatic gonad development variant" ; rdfs:subClassOf obo:WBPhenotype_0000399, obo:WBPhenotype_0001675 . obo:WBPhenotype_0002189 obo:IAO_0000115 "Animals produce an excess number of linker cells compared to controls." ; oboInOwl:hasExactSynonym "excess linker cells" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002189" ; a owl:Class ; rdfs:label "extra linker cells" ; rdfs:subClassOf obo:WBPhenotype_0001675, obo:WBPhenotype_0002175 . obo:WBPhenotype_0002190 obo:IAO_0000115 "The population of hypodermal cells is reduced compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002190" ; a owl:Class ; rdfs:label "fewer hypodermal cells" ; rdfs:subClassOf obo:WBPhenotype_0002174 . obo:WBPhenotype_0002191 obo:IAO_0000115 "Animals produce a reduced number of sex myoblasts compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002191" ; a owl:Class ; rdfs:label "fewer sex myoblasts" ; rdfs:subClassOf obo:WBPhenotype_0002174 . obo:WBPhenotype_0002192 obo:IAO_0000115 "Animals produce an excess number of sex myoblasts compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002192" ; a owl:Class ; rdfs:label "extra sex myoblasts" ; rdfs:subClassOf obo:WBPhenotype_0002175 . obo:WBPhenotype_0002193 obo:IAO_0000115 "The orientation of the progeny of P7.p mimic those of P5.p and face towards the posterior of the worm, a phenotype referred to as posterior-reversed vulval lineage (P-Rvl)." ; oboInOwl:hasBroadSynonym "P-Rvl" ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002193" ; a owl:Class ; rdfs:label "posterior reversed vulval lineage" ; rdfs:subClassOf obo:WBPhenotype_0000220, obo:WBPhenotype_0000239 . obo:WBPhenotype_0002194 obo:IAO_0000115 "Animals do not differ in size when grown on different food sources to the same extent as that measured for control animals. For example, in C. elegans, wild type worms are 1.65 times larger when grown on HB101 compared to those grown on OP50." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002194" ; a owl:Class ; rdfs:label "food dependent body size variant" ; rdfs:subClassOf obo:WBPhenotype_0002195 . obo:WBPhenotype_0002195 obo:IAO_0000115 "Animals exhibit variations in growth rate or the outcome of growth in response to food compared to control. In C. elegans, animals exhibit an increase or decrease in growth rate depending on the type of bacteria they are fed." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002195" ; a owl:Class ; rdfs:label "food dependent growth variant" ; rdfs:subClassOf obo:WBPhenotype_0001072 . obo:WBPhenotype_0002196 obo:IAO_0000115 "The driving force of the outward flow of ions does not exceed the inward flow for the opposite driving force or is otherwise altered when compared to that measured for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002196" ; a owl:Class ; rdfs:label "outward rectifying current variant" ; rdfs:subClassOf obo:WBPhenotype_0002197 . obo:WBPhenotype_0002197 obo:IAO_0000115 "Catalysis of the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded is altered from that observed for controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002197" ; a owl:Class ; rdfs:label "voltage gated channel activity variant" ; rdfs:subClassOf obo:WBPhenotype_0001315 . obo:WBPhenotype_0002198 obo:IAO_0000115 "The proper localization and assembly of components at the junction of a neuron with a muscle cell varies from that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002198" ; a owl:Class ; rdfs:label "neuromuscular junction organization variant" ; rdfs:subClassOf obo:WBPhenotype_0000625 . obo:WBPhenotype_0002199 obo:IAO_0000115 "The degree of stimulus-evoked calcium concentration changes differs from that of controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002199" ; a owl:Class ; rdfs:label "neuron calcium transient levels variant" ; rdfs:subClassOf obo:WBPhenotype_0002563 . obo:WBPhenotype_0002200 obo:IAO_0000115 "Variations in the progression of the muscles of the adult hermaphrodite oviduct over time from their initial formation to their mature structure compared to control." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002200" ; a owl:Class ; rdfs:label "oviduct muscle defective" ; rdfs:subClassOf obo:WBPhenotype_0000282 . obo:WBPhenotype_0002201 obo:IAO_0000115 "Dying animals cells exhibit defects in the fragmentation of chromosomal DNA into oligonucleosomal-length fragments compared to control animals. This process can be monitored by the quantity and quality of TUNEL (TdT-mediated dUTP nick end labeling)-positive nuclei." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002201" ; a owl:Class ; rdfs:label "apoptotic DNA degradation defective" ; rdfs:subClassOf obo:WBPhenotype_0000730 . obo:WBPhenotype_0002202 obo:IAO_0000115 "Embryos exhibit defects in the extension of pharyngeal cells toward the buccal opening during embryogenesis compared to controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002202" ; a owl:Class ; rdfs:label "pharynx extension defective" ; rdfs:subClassOf obo:WBPhenotype_0001748 . obo:WBPhenotype_0002203 obo:IAO_0000115 "Corpses resulting from programmed cell death appear different in size or shape from those of corpses in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002203" ; a owl:Class ; rdfs:label "corpse morphology variant" ; rdfs:subClassOf obo:WBPhenotype_0000730 . obo:WBPhenotype_0002204 obo:IAO_0000115 "Animals exhibit defects in the muscle contractions of the anterior region of corpus, the area responsible for allowing food to enter the corpus." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002204" ; a owl:Class ; rdfs:label "procorpus contraction defective" ; rdfs:subClassOf obo:WBPhenotype_0000327 . obo:WBPhenotype_0002205 obo:IAO_0000115 "Animals exhibit negative effects on growth, development, or metabolism when exposed to a galactose-rich diet, compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002205" ; a owl:Class ; rdfs:label "hypersensitive to galactose" ; rdfs:subClassOf obo:WBPhenotype_0000027, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28260 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_28260 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002206 obo:IAO_0000115 "Animals process dietary galactose differently than control animals, these differences can result in increased and or decreased levels of intermediary galactose metabolites." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002206" ; a owl:Class ; rdfs:label "galactose metabolism variant" ; rdfs:subClassOf obo:WBPhenotype_0000027 . obo:WBPhenotype_0002207 obo:IAO_0000115 "Animals are missing one or both gonad arms, the normally U-shaped projections of the gonad that extend into the anterior or posterior of the animal and bends back towards the center of the animal." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002207" ; a owl:Class ; rdfs:label "missing gonad arms" ; rdfs:subClassOf obo:WBPhenotype_0000399 . obo:WBPhenotype_0002208 obo:IAO_0000115 "The expression of a protein, as determined by antibody staining, varied from controls with respect to timing such that the protein was observed to be expressed at earlier timepoints or later timepoints than controls." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002208" ; a owl:Class ; rdfs:label "antibody temporal expression variant" ; rdfs:subClassOf obo:WBPhenotype_0000424 . obo:WBPhenotype_0002209 obo:IAO_0000115 "Any variation in the development of the structure that lies on the ventral surface just anterior and central to the base of the spicule openings (small lump on the gubernaculum of the male tail) and contains a sensory structure called the hook sensillum, compared to control. In C. elegans the hook is necessary for proper male mating." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002209" ; a owl:Class ; rdfs:label "hook development variant" ; rdfs:subClassOf obo:WBPhenotype_0000624, obo:WBPhenotype_0001297, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0008425 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:GO_0032502 [ a owl:Restriction ; owl:onProperty obo:RO_0002295 ; owl:someValuesFrom obo:WBbt_0008425 ] ) ] ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002210 obo:IAO_0000115 "Animals exhibit an extra number of the finger-like sensory sensilla that project from the tail and embed in the male fan." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002210" ; a owl:Class ; rdfs:label "extra rays" ; rdfs:subClassOf obo:WBPhenotype_0000199 . obo:WBPhenotype_0002211 obo:IAO_0000115 "Animals exhibit defects in dye-filling of the neuronal cells of the phasmid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002211" ; a owl:Class ; rdfs:label "phasmid neuron dye filling defect" ; rdfs:subClassOf obo:WBPhenotype_0000257, obo:WBPhenotype_0002535 . obo:WBPhenotype_0002212 obo:IAO_0000115 "Animals exhibit defects in dye-filling of the neuronal cells of the amphid sensilla. In C. elegans, these neurons are commonly assayed by dye-filling with FITC, DiI or DiO." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002212" ; a owl:Class ; rdfs:label "amphid neuron dye filling defect" ; rdfs:subClassOf obo:WBPhenotype_0000256, obo:WBPhenotype_0002535 . obo:WBPhenotype_0002213 obo:IAO_0000115 "Any variation that results in a decrease in the catalytic phosphorylation activity of a kinase enzyme compared to control. Catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein (can include an RNA component). Kinases are enzymes capable of phosphorylating their respective substrates." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002213" ; a owl:Class ; rdfs:label "kinase activity reduced" ; rdfs:subClassOf obo:WBPhenotype_0000124 . obo:WBPhenotype_0002214 obo:IAO_0000115 "Animals contain an excess number of pharyngeal muscle cells compared to control. In C. elegans, pharyngeal cells are derived from MS-blastomere. The overproduction of pharyngeal tissues is a result of other blastomeres adopting an MS-like fate." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002214" ; a owl:Class ; rdfs:label "extra pharyngeal muscle cells" ; rdfs:subClassOf obo:WBPhenotype_0001635 . obo:WBPhenotype_0002215 obo:IAO_0000115 "Any variation that results in a fewer than control number of body wall muscle cells." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002215" ; a owl:Class ; rdfs:label "fewer body wall muscles" ; rdfs:subClassOf obo:WBPhenotype_0001597 . obo:WBPhenotype_0002216 obo:IAO_0000115 "Any variation in the cellular or subcellular distribution of a gene product, as detected by antibody staining, compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002216" ; a owl:Class ; rdfs:label "pattern antibody staining variant" ; rdfs:subClassOf obo:WBPhenotype_0000424 . obo:WBPhenotype_0002217 obo:IAO_0000115 "Animals respond to antimony at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002217" ; a owl:Class ; rdfs:label "antimony hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_30513 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_30513 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002218 obo:IAO_0000115 "Animals respond to arsenite at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002218" ; a owl:Class ; rdfs:label "arsenite hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_22633 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_22633 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002219 obo:IAO_0000115 "Animals respond to fluoranthene at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002219" ; a owl:Class ; rdfs:label "fluoranthene hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_33083 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_33083 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002220 obo:IAO_0000115 "Animals respond to antimonite at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002220" ; a owl:Class ; rdfs:label "antimonite hypersensitivity" ; rdfs:subClassOf obo:WBPhenotype_0002217, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_30297 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_30297 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002221 obo:IAO_0000115 "The pharynx contains cavities, possibly indicative of inappropriate cell death." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002221" ; a owl:Class ; rdfs:label "pharyngeal vacuole" ; rdfs:subClassOf obo:WBPhenotype_0001363, obo:WBPhenotype_0002615 . obo:WBPhenotype_0002222 obo:IAO_0000115 "The uterus contains cavities, possibly indicative of inappropriate cell death." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002222" ; a owl:Class ; rdfs:label "uterus vacuole" ; rdfs:subClassOf obo:WBPhenotype_0001395 . obo:WBPhenotype_0002223 obo:IAO_0000115 "Animals respond at a faster rate or to lower concentrations of manganese that that observed for control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002223" ; a owl:Class ; rdfs:label "manganese hypersensitivity" ; rdfs:subClassOf obo:WBPhenotype_0001863, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18291 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_18291 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002224 obo:IAO_0000115 "Animals respond to mercury at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002224" ; a owl:Class ; rdfs:label "mercury hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000591, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25195 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25195 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002225 obo:IAO_0000115 "Animals respond to lead at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002225" ; a owl:Class ; rdfs:label "lead hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0001918, obo:WBPhenotype_0002227, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25016 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_25016 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002226 obo:IAO_0000115 "Animals respond to cobalt at a lower concentration or a shorter exposure compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002226" ; a owl:Class ; rdfs:label "cobalt hypersensitive" ; rdfs:subClassOf obo:WBPhenotype_0000591, obo:WBPhenotype_0001918, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27638 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001651 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:CARO_0010004 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002503 ; owl:someValuesFrom obo:CHEBI_27638 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002227 obo:IAO_0000115 "Animals exhibit variations in their response to lead compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002227" ; a owl:Class ; rdfs:label "lead response variant" ; rdfs:subClassOf obo:WBPhenotype_0000523, obo:WBPhenotype_0000591, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010288 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010288 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002228 obo:IAO_0000115 "Animals exhibit variations in their response to aluminum compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002228" ; a owl:Class ; rdfs:label "aluminum response variant" ; rdfs:subClassOf obo:WBPhenotype_0000523, obo:WBPhenotype_0000591, [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010044 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] ; owl:equivalentClass [ a owl:Restriction ; owl:onProperty obo:BFO_0000051 ; owl:someValuesFrom [ a owl:Class ; owl:intersectionOf (obo:PATO_0001236 [ a owl:Restriction ; owl:onProperty obo:RO_0000052 ; owl:someValuesFrom obo:GO_0010044 ] [ a owl:Restriction ; owl:onProperty obo:RO_0002573 ; owl:someValuesFrom obo:PATO_0000460 ] ) ] ] . obo:WBPhenotype_0002229 obo:IAO_0000115 "Animals exhibit variations in their response to chromium compared to that observed in control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002229" ; a owl:Class ; rdfs:label "chromium response variant" ; rdfs:subClassOf obo:WBPhenotype_0000591 . obo:WBPhenotype_0002230 obo:IAO_0000115 "Animals exhibited higher amounts of internal metal concentrations compared to control animals." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002230" ; a owl:Class ; rdfs:label "metal accumulation increased" ; rdfs:subClassOf obo:WBPhenotype_0002029 . obo:WBPhenotype_0002231 obo:IAO_0000115 "Oxidative stress induced by manganese differs from that of control worms." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002231" ; a owl:Class ; rdfs:label "manganese induced oxidative stress response" ; rdfs:subClassOf obo:WBPhenotype_0001620 . obo:WBPhenotype_0002232 obo:IAO_0000115 "The polarity reversal process by which synaptic components are removed from one side of the synapse and then reformed on the opposite cell does not occur or occurs in a different manner than in controls. In C. elegans, at the end of the L1 stage, the DD neurons undergo a complete polarity reversal such that the ventral synapses disappear and new synapses are formed on opposing dorsal body muscles." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002232" ; a owl:Class ; rdfs:label "synaptic remodeling variant" ; rdfs:subClassOf obo:WBPhenotype_0000625 . obo:WBPhenotype_0002233 obo:IAO_0000115 "The swimming behavior of animals are influenced or modulate by the osmolarity of the swimming buffer. The swimming of wild-type C. elegans animals are not affected by the osmolarity of the swimming liquid." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002233" ; a owl:Class ; rdfs:label "osmolarity modulated swimming variant" ; rdfs:subClassOf obo:WBPhenotype_0000876 . obo:WBPhenotype_0002234 obo:IAO_0000115 "Animals contain excess acidified intracellular compartments. These compartments are positive for indicators such as Acridine Orange as well as LysoTracker Red, in a lysosome-like manner." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:0002234" ; a owl:Class ; rdfs:label "increased acidified compartments" ; rdfs:subClassOf obo:WBPhenotype_0001393 . obo:WBPhenotype_0002235 obo:IAO_0000115 "Animals are unable to grow on media depleted of phosphate." ; oboInOwl:hasOBONamespace "C_elegans_phenotype_ontology" ; oboInOwl:id "WBPhenotype:00